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MN234170.1__QFG08859.1__PBI_MALAGASYROSE_9__00007

Bact-Vir

MN234170.1__QFG08859.1__PBI_MALAGASYROSE_9__00007

Identity

Accession:
MN234170 ↗
Kingdom:
phage

Quality

83.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 275-391
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF18451.8 best CdiA_C 57.0 2.60e-15 65.8% 95.1%
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4g6vA00 3.40.1350.120 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.83 78.0 7.49e-01 100.0% 97.0%
3s2cA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.66 52.0 3.75e-01 84.6% 96.8%
5kzkA02 3.40.1280.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain 0.66 40.0 3.61e-01 74.4% 44.9%
3gyqA02 3.40.1280.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain 0.63 40.0 3.58e-01 79.5% 45.1%
3if5A02 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.62 42.0 4.69e-01 88.9% 91.0%
3lklA00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.61 41.0 4.48e-01 87.2% 84.9%
7tbvB02 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.61 56.0 4.38e-01 100.0% 68.8%
2o3jB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 52.0 4.37e-01 99.1% 88.1%
4qtpD00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.59 45.0 4.55e-01 90.6% 81.7%
3ro6A02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.59 47.0 3.76e-01 87.2% 87.1%
1vc1A00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.58 46.0 4.73e-01 90.6% 88.2%
5lddC00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 48.0 4.33e-01 92.3% 88.1%
4dghA00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.58 46.0 4.47e-01 100.0% 77.3%
4wfsA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.57 52.0 4.22e-01 100.0% 82.9%
4xs5B00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.57 43.0 4.44e-01 91.5% 82.5%
3ny7A00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.57 45.0 4.54e-01 91.5% 83.1%
5dj1A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.57 51.0 4.09e-01 100.0% 59.1%
3bofA02 3.20.20.20 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like 0.56 51.0 3.94e-01 100.0% 70.4%
1losA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.56 51.0 4.16e-01 100.0% 63.9%
4rkcA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 48.0 3.86e-01 95.7% 57.0%
4dg8A01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.56 49.0 3.46e-01 100.0% 72.2%
6m37B01 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.55 42.0 4.58e-01 90.6% 96.9%
3kbqB00 3.40.980.10 Alpha Beta › 3-Layer(aba) Sandwich › Molybdenum Cofactor Biosythetic Enzyme; Chain A › MoaB/Mog-like domain 0.55 46.0 4.12e-01 90.6% 85.2%
6fgcA01 3.40.980.10 Alpha Beta › 3-Layer(aba) Sandwich › Molybdenum Cofactor Biosythetic Enzyme; Chain A › MoaB/Mog-like domain 0.55 47.0 4.08e-01 92.3% 70.7%
1u8xX01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 46.0 4.10e-01 89.7% 99.4%
3qz6A00 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.55 49.0 3.81e-01 99.1% 88.0%
3sjnA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.55 50.0 3.87e-01 100.0% 61.8%
3d0cB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 49.0 3.67e-01 100.0% 57.3%
3gfoA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 49.0 3.84e-01 100.0% 79.3%
4cgyA01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 45.0 3.99e-01 92.3% 87.5%
2qhpA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.54 48.0 3.59e-01 96.6% 73.3%
4dgfA00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.54 44.0 4.36e-01 91.5% 83.6%
2yfkA01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.54 44.0 3.78e-01 90.6% 54.5%
1jz7A03 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.54 49.0 3.66e-01 100.0% 49.8%
3ck2A00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.54 43.0 3.80e-01 85.5% 87.9%
2nvwB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 48.0 4.08e-01 100.0% 90.3%
1v77A00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.54 43.0 3.65e-01 87.2% 74.3%
5jd6A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 46.0 3.81e-01 99.1% 97.3%
1xngA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.52 41.0 3.28e-01 84.6% 89.9%
1h4xA00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.52 40.0 4.12e-01 91.5% 86.5%
3op2A02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.52 47.0 3.71e-01 100.0% 54.3%
4qjiB00 3.40.50.10300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CoaB-like 0.52 46.0 3.81e-01 100.0% 93.5%
7w6bA01 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.51 43.0 3.33e-01 92.3% 97.8%
2ocgA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 44.0 3.54e-01 99.1% 99.6%
2yz2B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 45.0 3.54e-01 100.0% 75.7%
1pzxB01 3.40.50.10440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1 0.51 44.0 4.35e-01 93.2% 96.7%
7zdgC02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 44.0 3.61e-01 100.0% 85.8%
2g40A00 3.40.50.10420 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NagB/RpiA/CoA transferase-like 0.50 44.0 3.95e-01 95.7% 79.3%
1sgwA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 44.0 3.77e-01 100.0% 91.0%
1vplA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 44.0 3.57e-01 100.0% 82.8%
4eogA01 3.40.50.10640 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SSO1389-like 0.50 45.0 3.36e-01 100.0% 67.8%
4opmA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.50 44.0 3.35e-01 100.0% 93.6%
ECOD (71)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
221595 2008.1.1.69 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › CdiA_C 0.83 78.0 7.49e-01 100.0% 97.0%
4956317 7542.1.2.3 a/b three-layered sandwiches › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain II › AcnX_2nd 0.70 42.0 4.81e-01 78.6% 81.2%
3404650 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.68 56.0 5.02e-01 88.0% 82.5%
4966826 2008.1.1.16 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat 0.68 53.0 5.41e-01 88.9% 85.2%
4008063 2008.1.1.197 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27347 0.68 52.0 5.45e-01 81.2% 94.3%
3412401 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.67 56.0 4.93e-01 88.9% 82.4%
3404837 7585.1.1.0 a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins 0.67 56.0 5.04e-01 88.9% 85.2%
5030819 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.66 57.0 5.47e-01 92.3% 96.2%
3407355 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.66 56.0 4.93e-01 91.5% 84.1%
4939438 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.64 54.0 5.07e-01 91.5% 92.1%
4947458 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.64 54.0 5.08e-01 91.5% 91.4%
4667958 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.63 57.0 4.53e-01 100.0% 73.6%
138474 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.61 41.0 4.48e-01 87.2% 84.9%
3988704 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.61 42.0 4.29e-01 89.7% 72.2%
2834000 2002.1.1.66 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DHquinase_I 0.61 56.0 4.28e-01 100.0% 64.2%
3251448 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.60 55.0 3.67e-01 100.0% 93.4%
4488209 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.60 51.0 5.16e-01 98.3% 92.4%
5025937 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.60 47.0 4.70e-01 93.2% 82.5%
3838643 2496.1.1.0 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like 0.60 42.0 4.53e-01 90.6% 86.0%
4935861 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.59 52.0 5.18e-01 98.3% 94.2%
5080532 2008.4.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › TBP-interacting protein N-terminal domain-like › TBP-interacting protein N-terminal domain-like 0.59 48.0 4.97e-01 92.3% 95.4%
4334568 2002.1.1.9 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › OMPdecase 0.58 53.0 4.01e-01 100.0% 54.0%
4000167 2008.6.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Acetyl-CoA carboxylase AC4 and AC5 domains › Acetyl-CoA carboxylase AC4 and AC5 domains 0.58 54.0 4.87e-01 100.0% 81.3%
3638250 2002.1.1.9 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › OMPdecase 0.58 52.0 3.94e-01 100.0% 54.0%
3974592 2496.1.1.5 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS_2 0.58 44.0 4.68e-01 89.7% 94.0%
3462793 207.1.1.79 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › F-box 0.57 49.0 3.24e-01 94.0% 43.0%
5022883 2002.1.1.112 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_114 0.57 51.0 3.85e-01 100.0% 73.2%
4113427 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.57 48.0 4.16e-01 90.6% 81.7%
3980038 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.57 45.0 4.52e-01 91.5% 81.7%
3599009 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.57 45.0 3.68e-01 87.2% 81.2%
4992739 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.57 48.0 4.47e-01 92.3% 81.3%
3288712 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.57 46.0 4.55e-01 100.0% 82.4%
5017349 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.57 47.0 4.33e-01 90.6% 71.6%
4933165 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.56 48.0 4.28e-01 92.3% 72.7%
4950135 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.56 48.0 4.24e-01 91.5% 73.3%
4150182 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.56 47.0 4.09e-01 90.6% 83.9%
5038840 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.56 43.0 4.63e-01 100.0% 97.0%
4255393 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.56 46.0 4.11e-01 88.0% 84.8%
4040793 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.56 47.0 4.16e-01 90.6% 85.9%
5015343 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.56 47.0 4.21e-01 91.5% 79.4%
4954122 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.56 47.0 4.12e-01 91.5% 69.7%
4217210 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.56 47.0 4.08e-01 91.5% 81.7%
4392313 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.56 46.0 4.28e-01 92.3% 92.9%
3997288 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.56 47.0 4.01e-01 91.5% 69.7%
4983295 2003.6.1.1 a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › PfkB 0.56 49.0 3.68e-01 99.1% 72.5%
3972343 2484.6.1.0 mixed a+b and a/b › Ribonuclease H-like › Periplasmic domain of ExbD/TolR › Periplasmic domain of ExbD/TolR 0.55 39.0 4.32e-01 92.3% 94.4%
3386525 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.55 38.0 4.30e-01 89.7% 96.5%
3431930 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.55 47.0 4.21e-01 92.3% 78.2%
4523185 7570.1.1.1 a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C 0.55 46.0 4.21e-01 97.4% 66.9%
4206570 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.55 46.0 4.51e-01 93.2% 84.0%
1242007 2002.1.1.174 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › MR_MLE_C 0.55 50.0 3.89e-01 100.0% 62.2%
3282382 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.55 47.0 4.34e-01 95.7% 72.7%
4982595 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.55 46.0 4.25e-01 91.5% 79.4%
4032583 7541.1.1.1 a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.55 47.0 4.14e-01 92.3% 72.4%
4393621 246.1.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase 0.55 50.0 3.78e-01 100.0% 59.0%
3956491 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.55 43.0 4.26e-01 90.6% 78.4%
138986 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.55 45.0 4.41e-01 91.5% 82.0%
5009930 7592.1.1.6 a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › Csa3_N 0.54 45.0 4.32e-01 90.6% 95.6%
4674560 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.54 45.0 4.35e-01 95.7% 79.3%
3995931 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.54 49.0 3.32e-01 100.0% 90.0%
3287956 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.54 48.0 4.41e-01 98.3% 78.0%
3531324 207.1.1.22 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_6 0.53 46.0 2.71e-01 96.6% 11.3%
3667361 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.53 48.0 4.28e-01 100.0% 73.8%
164102 2003.6.1.1 a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › PfkB 0.53 44.0 3.26e-01 92.3% 54.7%
3826072 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.53 48.0 4.41e-01 100.0% 78.5%
4958578 2007.1.14.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like 0.52 43.0 4.12e-01 91.5% 87.4%
5079620 2005.1.1.20 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ThiI 0.51 45.0 3.70e-01 96.6% 67.4%
5053615 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.51 45.0 3.85e-01 99.1% 78.4%
3970720 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.51 44.0 4.28e-01 99.1% 97.0%
3629417 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.50 42.0 3.63e-01 91.5% 71.4%
3263466 2003.1.1.58 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_4 0.50 43.0 3.09e-01 100.0% 65.2%
D2 medium residues 1-131
PDB
Domain cluster: representative
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ljbA00 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.68 61.0 5.19e-01 100.0% 83.1%
5tgzA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.66 46.0 3.54e-01 71.8% 36.0%
8h8jC01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 46.0 3.67e-01 80.2% 41.3%
3frrA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.60 44.0 3.99e-01 77.1% 89.2%
3rzeA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.59 41.0 3.30e-01 71.8% 37.3%
3wvoC02 1.10.132.100 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.59 40.0 4.08e-01 80.9% 70.8%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.58 46.0 4.80e-01 98.5% 92.4%
2l6xA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 50.0 4.19e-01 96.2% 78.3%
8itfR01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.57 40.0 3.13e-01 71.8% 36.1%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 42.0 3.49e-01 77.9% 85.5%
6w08A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.55 46.0 3.41e-01 90.1% 90.5%
1qoyA00 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.55 47.0 3.60e-01 92.4% 73.3%
7sf8A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 42.0 3.44e-01 80.2% 46.1%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.55 41.0 4.52e-01 77.1% 100.0%
7wujE01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 44.0 3.53e-01 86.3% 67.9%
3l39A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.54 45.0 3.91e-01 90.1% 92.5%
1c17M00 1.20.120.220 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A 0.53 47.0 4.58e-01 98.5% 90.1%
1ymgA00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.53 45.0 3.69e-01 90.8% 86.3%
5u1aL00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 44.0 4.06e-01 87.8% 100.0%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.53 39.0 4.07e-01 97.7% 85.6%
3p1uA00 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 44.0 2.98e-01 91.6% 83.3%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 42.0 4.10e-01 91.6% 78.6%
3u9jA00 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.52 43.0 4.12e-01 92.4% 75.2%
3hq2B00 1.10.1370.30 Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › 0.52 43.0 2.97e-01 90.8% 82.5%
1xioA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 44.0 3.75e-01 93.9% 82.9%
2w53B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 42.0 3.85e-01 88.5% 66.5%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.51 37.0 4.15e-01 75.6% 98.0%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.51 40.0 4.08e-01 99.2% 84.0%
2d4xA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.51 43.0 3.70e-01 93.1% 79.9%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.51 41.0 4.31e-01 91.6% 96.6%
3k66A01 1.20.120.770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain 0.51 37.0 3.23e-01 76.3% 49.3%
3hl1B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 37.0 3.16e-01 75.6% 98.6%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.50 44.0 4.40e-01 97.7% 94.0%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 35.0 3.17e-01 72.5% 57.3%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3205696 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.62 48.0 4.74e-01 79.4% 98.5%
4933576 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.61 53.0 4.84e-01 99.2% 77.2%
4337352 3227.1.1.1 alpha complex topology › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › PTS_EIIC 0.60 45.0 3.20e-01 77.1% 27.1%
4944200 5059.1.1.67 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › AsnC_trans_reg 0.59 43.0 3.23e-01 76.3% 66.6%
3929690 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.57 49.0 4.28e-01 100.0% 63.2%
5003920 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.56 49.0 4.48e-01 100.0% 76.1%
3695840 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.56 49.0 3.89e-01 98.5% 76.4%
3554277 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.55 48.0 3.64e-01 94.7% 83.1%
3861849 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.55 48.0 3.60e-01 94.7% 81.5%
3493454 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.55 42.0 3.56e-01 79.4% 83.3%
3700262 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.54 49.0 4.76e-01 100.0% 97.9%
4356766 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.54 39.0 3.62e-01 75.6% 90.9%
4647650 3755.4.1.24 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › DUF2463 0.54 46.0 3.68e-01 93.9% 80.0%
3411201 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.54 45.0 4.07e-01 98.5% 66.1%
3721451 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.54 40.0 3.70e-01 77.9% 97.1%
4974774 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.54 46.0 3.91e-01 96.2% 77.2%
3225005 192.29.1.31 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CRIC_ras_sig 0.53 43.0 4.36e-01 95.4% 86.2%
3265039 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.53 43.0 3.52e-01 90.1% 75.9%
3990409 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.53 44.0 4.14e-01 89.3% 96.9%
3798573 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.53 45.0 4.29e-01 98.5% 78.7%
4974154 150.1.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin 0.53 45.0 4.11e-01 90.8% 97.6%
3619083 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.53 46.0 4.59e-01 93.9% 94.1%
3797268 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.53 42.0 4.08e-01 99.2% 76.7%
3737954 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 44.0 4.22e-01 98.5% 79.3%
3392851 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 47.0 4.14e-01 100.0% 74.0%
3716232 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.52 47.0 4.55e-01 100.0% 92.7%
5060740 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.52 47.0 3.60e-01 99.2% 91.5%
3646014 604.1.1.61 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF6857 0.52 39.0 3.26e-01 77.1% 62.2%
3867721 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.52 44.0 3.66e-01 95.4% 76.4%
3709603 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.52 46.0 4.52e-01 100.0% 89.0%
3562194 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.52 43.0 4.12e-01 95.4% 75.3%
3779698 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.52 43.0 3.58e-01 93.9% 73.7%
5068349 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.52 42.0 4.34e-01 90.1% 94.2%
3633924 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.51 42.0 3.58e-01 87.8% 84.2%
3253932 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.51 43.0 4.38e-01 94.7% 96.0%
3634360 601.1.1.123 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF7784 0.51 45.0 4.06e-01 98.5% 74.6%
3908397 5001.1.1.3 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.51 41.0 3.23e-01 85.5% 45.7%
3474225 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.51 41.0 4.33e-01 91.6% 95.8%
3215638 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.50 43.0 3.41e-01 95.4% 69.7%
3304304 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.50 36.0 3.99e-01 74.8% 100.0%
3640096 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.50 45.0 3.66e-01 100.0% 65.1%
3337403 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.50 42.0 3.77e-01 90.8% 93.5%
3697212 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 36.0 2.33e-01 100.0% 16.8%
3709598 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.50 45.0 4.30e-01 100.0% 87.7%
D3 medium residues 132-270
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF25310.2 best VG15 60.2 4.80e-16 67.6% 28.8%