←Back to structures
MN234216.1__QFG13316.1__SEA_GILGAMESH_124__00124
Bact-VirMN234216.1__QFG13316.1__SEA_GILGAMESH_124__00124
Identity
- Accession:
- MN234216 ↗
- Kingdom:
- phage
Quality
82.3
mean pLDDT
Taxonomy
TaxID: 2599890
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 196-261
Domain cluster:
rep: MH001457.1__AVO22306.1__PBI_NESBITT_49__00049__D2-62
CATH (54)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5jh8A02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.70 | 54.0 | 5.41e-01 | 90.9% | 82.1% |
| 4wiwA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.67 | 56.0 | 5.52e-01 | 90.9% | 100.0% |
| 3buuB00 | 2.50.20.10 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX | 0.66 | 55.0 | 3.88e-01 | 93.9% | 82.3% |
| 4v0bA00 | 3.30.720.210 | Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › | 0.66 | 41.0 | 4.20e-01 | 87.9% | 65.1% |
| 3cz8A02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.66 | 53.0 | 5.63e-01 | 87.9% | 100.0% |
| 4emoC00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.63 | 52.0 | 4.38e-01 | 92.4% | 65.5% |
| 2rk0A01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.63 | 48.0 | 4.00e-01 | 86.4% | 46.3% |
| 3rheA00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.62 | 48.0 | 4.06e-01 | 90.9% | 49.1% |
| 4jpdA00 | 3.30.920.10 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY | 0.62 | 47.0 | 4.06e-01 | 100.0% | 50.5% |
| 1aqcB00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.60 | 50.0 | 4.09e-01 | 92.4% | 73.8% |
| 4huzA01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.60 | 49.0 | 3.77e-01 | 95.5% | 76.5% |
| 1zswA01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.59 | 48.0 | 3.65e-01 | 95.5% | 69.1% |
| 1kafA00 | 3.90.1150.20 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription regulator MotA, C-terminal domain | 0.59 | 41.0 | 3.50e-01 | 72.7% | 63.9% |
| 2yf0A01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.59 | 49.0 | 4.51e-01 | 92.4% | 78.2% |
| 1q67A01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.58 | 49.0 | 3.85e-01 | 93.9% | 74.3% |
| 4zgfA00 | 2.40.128.270 | Mainly Beta › Beta Barrel › Lipocalin › | 0.58 | 50.0 | 3.99e-01 | 100.0% | 93.6% |
| 3oreA01 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.57 | 40.0 | 4.03e-01 | 74.2% | 87.9% |
| 1h4rA03 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.57 | 47.0 | 4.28e-01 | 92.4% | 71.4% |
| 3oajA02 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.56 | 46.0 | 3.69e-01 | 95.5% | 91.0% |
| 3qijB03 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.56 | 47.0 | 4.25e-01 | 92.4% | 69.7% |
| 3e0rB01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.56 | 45.0 | 3.78e-01 | 92.4% | 98.3% |
| 3n5mB01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.55 | 46.0 | 3.42e-01 | 93.9% | 66.5% |
| 3dxvA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.55 | 46.0 | 3.55e-01 | 93.9% | 73.0% |
| 1zodA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.55 | 46.0 | 3.61e-01 | 93.9% | 80.1% |
| 3i4jB01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 45.0 | 3.62e-01 | 93.9% | 70.8% |
| 2pb2B01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 45.0 | 3.58e-01 | 93.9% | 72.5% |
| 4uoyA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 45.0 | 3.26e-01 | 93.9% | 52.0% |
| 6torA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 45.0 | 3.55e-01 | 93.9% | 75.7% |
| 4huzA02 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.54 | 42.0 | 3.37e-01 | 90.9% | 78.8% |
| 3oksA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 46.0 | 3.39e-01 | 95.5% | 63.1% |
| 3fcrA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 45.0 | 3.33e-01 | 93.9% | 64.2% |
| 4nogA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 45.0 | 3.37e-01 | 93.9% | 59.6% |
| 6g4bA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.54 | 45.0 | 3.38e-01 | 93.9% | 64.3% |
| 2xdoD00 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.53 | 45.0 | 2.76e-01 | 100.0% | 16.5% |
| 1ohvA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.53 | 44.0 | 3.38e-01 | 95.5% | 61.4% |
| 5g0aA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.53 | 44.0 | 3.25e-01 | 93.9% | 66.3% |
| 3nx3A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.53 | 44.0 | 3.52e-01 | 95.5% | 71.6% |
| 1ou8A00 | 2.30.30.220 | Mainly Beta › Roll › SH3 type barrels. › SspB-like | 0.53 | 45.0 | 3.85e-01 | 95.5% | 74.5% |
| 2acaA00 | 2.40.320.10 | Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 | 0.53 | 47.0 | 3.45e-01 | 100.0% | 80.5% |
| 2cjgA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.53 | 44.0 | 3.41e-01 | 95.5% | 66.9% |
| 3nuiA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.53 | 44.0 | 3.43e-01 | 93.9% | 75.3% |
| 1vefA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.52 | 43.0 | 3.41e-01 | 93.9% | 67.6% |
| 4harA00 | 3.10.50.50 | Alpha Beta › Roll › Chitinase A; domain 3 › Rubella virus capsid protein | 0.52 | 43.0 | 3.80e-01 | 92.4% | 91.8% |
| 1tr0A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 36.0 | 3.16e-01 | 72.7% | 67.9% |
| 2ehbD00 | 3.30.310.80 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 | 0.52 | 44.0 | 3.64e-01 | 98.5% | 74.6% |
| 3dodB01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.52 | 43.0 | 3.25e-01 | 93.9% | 65.5% |
| 3ruyA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.52 | 43.0 | 3.43e-01 | 95.5% | 68.5% |
| 1azpA00 | 2.40.50.40 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.51 | 34.0 | 3.43e-01 | 89.4% | 68.2% |
| 4hs5A00 | 3.30.920.10 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY | 0.51 | 38.0 | 3.33e-01 | 100.0% | 51.4% |
| 3r7wC02 | 3.30.450.190 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.51 | 43.0 | 3.65e-01 | 92.4% | 67.3% |
| 1ibaA00 | 3.30.1360.60 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Glucose permease domain IIB | 0.51 | 38.0 | 3.61e-01 | 80.3% | 71.8% |
| 3hmuB01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.51 | 42.0 | 3.09e-01 | 93.9% | 59.9% |
| 2epjA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.51 | 40.0 | 3.11e-01 | 93.9% | 64.2% |
| 2ea9A01 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.50 | 41.0 | 3.68e-01 | 92.4% | 94.7% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3288866 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.61 | 51.0 | 4.18e-01 | 92.4% | 56.7% |
| 3390648 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.61 | 50.0 | 4.16e-01 | 92.4% | 59.2% |
| 2617501 | 3016.1.1.2 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 | 0.60 | 41.0 | 3.60e-01 | 71.2% | 68.3% |
| 3479756 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.58 | 48.0 | 4.18e-01 | 93.9% | 62.9% |
| 4948951 | 9.1.1.0 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins | 0.57 | 46.0 | 3.88e-01 | 92.4% | 92.5% |
| 865437 | 241.1.1.2 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › Autophagy_act_C | 0.57 | 43.0 | 3.37e-01 | 100.0% | 36.4% |
| 4949985 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.57 | 46.0 | 4.36e-01 | 90.9% | 78.8% |
| 3587556 | 284.2.1.0 ↗ | a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain | 0.56 | 45.0 | 4.48e-01 | 90.9% | 87.1% |
| 4948949 | 9.1.1.4 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META | 0.56 | 44.0 | 3.84e-01 | 87.9% | 99.0% |
| 3501913 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.56 | 46.0 | 3.64e-01 | 92.4% | 46.4% |
| 4384965 | 331.4.1.0 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 | 0.55 | 42.0 | 4.00e-01 | 83.3% | 93.8% |
| 4626774 | 4263.2.1.0 ↗ | a+b two layers › TTHA1528-like › FtsH Periplasmic Domain › FtsH Periplasmic Domain | 0.55 | 44.0 | 4.50e-01 | 90.9% | 100.0% |
| 4950145 | 9.1.1.4 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META | 0.55 | 45.0 | 3.74e-01 | 93.9% | 91.1% |
| 3422937 | 708.1.1.0 ↗ | beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain | 0.54 | 38.0 | 3.93e-01 | 74.2% | 81.7% |
| 4950140 | 9.1.1.4 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META | 0.52 | 41.0 | 3.54e-01 | 90.9% | 93.0% |
| 3594372 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.52 | 38.0 | 2.27e-01 | 80.3% | 19.8% |
| 4532472 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.52 | 37.0 | 3.36e-01 | 78.8% | 100.0% |
| 3691605 | 244.1.1.0 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C | 0.52 | 45.0 | 3.59e-01 | 100.0% | 48.5% |
| 4975323 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.52 | 47.0 | 4.21e-01 | 98.5% | 98.9% |
| 1147819 | 216.1.1.0 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like | 0.51 | 37.0 | 3.29e-01 | 75.8% | 54.5% |
| 3386462 | 274.1.1.0 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits | 0.51 | 40.0 | 3.44e-01 | 84.8% | 95.2% |
D2
high
residues 269-377
Domain cluster:
representative
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4nkbB02 | 3.30.1120.130 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.73 | 29.0 | 3.19e-01 | 80.7% | 44.4% |
| 5exvC00 | 3.40.1570.10 | Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains | 0.62 | 53.0 | 4.68e-01 | 95.4% | 81.2% |
| 2hqvA00 | 3.40.1570.10 | Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains | 0.62 | 53.0 | 4.58e-01 | 94.5% | 75.6% |
| 1tj6A00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.60 | 42.0 | 4.21e-01 | 73.4% | 82.6% |
| 3fm2A00 | 3.40.1570.10 | Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains | 0.59 | 44.0 | 4.12e-01 | 78.0% | 78.9% |
| 4zgfA00 | 2.40.128.270 | Mainly Beta › Beta Barrel › Lipocalin › | 0.59 | 45.0 | 4.10e-01 | 79.8% | 99.3% |
| 5j3uA01 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.58 | 35.0 | 3.40e-01 | 97.2% | 51.6% |
| 2vugA02 | 3.30.1490.70 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › | 0.58 | 35.0 | 4.04e-01 | 81.7% | 88.9% |
| 2oqbA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.58 | 40.0 | 4.11e-01 | 72.5% | 80.6% |
| 8t5tA01 | 2.50.20.10 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX | 0.57 | 41.0 | 3.53e-01 | 77.1% | 90.8% |
| 4e6xB00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.54 | 40.0 | 2.96e-01 | 78.0% | 86.0% |
| 4gdnC00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.54 | 40.0 | 2.89e-01 | 78.9% | 86.0% |
| 2qmiA01 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.53 | 39.0 | 2.82e-01 | 78.0% | 87.9% |
| 4okcA01 | 2.90.10.10 | Mainly Beta › Orthogonal Prism › Agglutinin, subunit A › Bulb-type lectin domain | 0.53 | 27.0 | 3.24e-01 | 78.0% | 73.9% |
| 5tgfD00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.52 | 39.0 | 2.82e-01 | 78.0% | 84.3% |
| 3h20A01 | 3.30.1490.240 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RepB DNA-primase, N-terminal domain | 0.52 | 32.0 | 3.83e-01 | 74.3% | 100.0% |
| 4ztkA00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.52 | 39.0 | 2.99e-01 | 79.8% | 76.9% |
| 4jxuA01 | 3.30.470.10 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain | 0.51 | 36.0 | 3.42e-01 | 72.5% | 96.9% |
| 6j5yA00 | 3.90.850.10 | Alpha Beta › Alpha-Beta Complex › Fumarylacetoacetate hydrolase; domain 2 › Fumarylacetoacetase-like, C-terminal domain | 0.51 | 42.0 | 3.34e-01 | 91.7% | 85.4% |
| 3rjuA00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.50 | 38.0 | 2.73e-01 | 80.7% | 89.2% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3718648 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.61 | 36.0 | 3.67e-01 | 100.0% | 59.3% |
| 1758949 | 4216.1.1.1 ↗ | a+b duplicates or obligate multimers › Heme iron utilization protein-like › Heme iron utilization protein-like › Heme iron utilization protein-like › HemS | 0.60 | 46.0 | 4.33e-01 | 81.7% | 75.7% |
| 1552185 | 9.1.1.26 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › DUF4847 | 0.59 | 45.0 | 4.10e-01 | 79.8% | 99.3% |
| 3601552 | 9.1.1.4 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META | 0.58 | 42.0 | 4.19e-01 | 74.3% | 99.1% |
| 4929392 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.56 | 33.0 | 3.56e-01 | 93.6% | 68.9% |
| 3077250 | 234.3.1.0 ↗ | a+b two layers › Microbial ribonucleases-like › Colicin D nuclease domain › Colicin D nuclease domain | 0.54 | 34.0 | 3.67e-01 | 100.0% | 76.1% |
| 3956344 | 4019.1.1.1 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.54 | 40.0 | 2.77e-01 | 78.0% | 86.0% |
| 5033269 | 4019.1.1.1 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.54 | 40.0 | 2.86e-01 | 78.0% | 85.3% |
| 3953538 | 4019.1.1.1 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.54 | 40.0 | 2.78e-01 | 78.0% | 79.7% |
| 3286484 | 4019.1.1.1 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.53 | 39.0 | 2.77e-01 | 78.0% | 83.0% |
| 3453009 | 4357.1.1.6 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE_5 | 0.53 | 37.0 | 4.15e-01 | 78.9% | 94.1% |
| 4323403 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.52 | 40.0 | 2.96e-01 | 82.6% | 77.6% |
| 3289478 | 4019.1.1.1 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.52 | 38.0 | 2.69e-01 | 77.1% | 84.9% |
| 3954895 | 4019.1.1.1 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.51 | 37.0 | 2.66e-01 | 78.0% | 83.2% |
| 3237024 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.50 | 36.0 | 3.56e-01 | 97.2% | 69.2% |
D3
high
residues 422-539
Domain cluster:
representative
CATH (54)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.86 | 61.0 | 5.82e-01 | 72.9% | 85.0% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.84 | 65.0 | 6.25e-01 | 79.7% | 86.3% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.81 | 61.0 | 5.92e-01 | 78.0% | 96.2% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.79 | 61.0 | 5.80e-01 | 80.5% | 92.0% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.78 | 64.0 | 5.48e-01 | 86.4% | 80.0% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.77 | 59.0 | 5.70e-01 | 80.5% | 95.5% |
| 2kbbA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.75 | 58.0 | 5.04e-01 | 80.5% | 66.7% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 63.0 | 6.07e-01 | 89.8% | 99.2% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.73 | 55.0 | 5.48e-01 | 78.8% | 91.7% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.73 | 55.0 | 4.59e-01 | 79.7% | 58.0% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.72 | 49.0 | 5.34e-01 | 84.7% | 82.0% |
| 1st6A03 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.72 | 61.0 | 4.82e-01 | 89.8% | 69.0% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.71 | 53.0 | 5.03e-01 | 83.9% | 65.5% |
| 2d4uB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.70 | 54.0 | 4.95e-01 | 81.4% | 88.4% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.69 | 50.0 | 5.22e-01 | 84.7% | 80.7% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 51.0 | 5.10e-01 | 83.9% | 77.5% |
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.67 | 52.0 | 5.10e-01 | 82.2% | 99.2% |
| 2vpzC00 | 1.20.1630.10 | Mainly Alpha › Up-down Bundle › Formate dehydrogenase/DMSO reductase fold › Formate dehydrogenase/DMSO reductase domain | 0.67 | 57.0 | 4.45e-01 | 92.4% | 92.4% |
| 3a7kB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 57.0 | 4.41e-01 | 92.4% | 82.2% |
| 1dk8A02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.66 | 46.0 | 5.21e-01 | 80.5% | 97.6% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 51.0 | 4.75e-01 | 85.6% | 67.1% |
| 1uddA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.65 | 46.0 | 3.72e-01 | 72.0% | 70.2% |
| 7eptR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.65 | 51.0 | 3.98e-01 | 83.1% | 84.6% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 50.0 | 4.73e-01 | 85.6% | 67.1% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.65 | 53.0 | 4.91e-01 | 89.0% | 94.8% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.64 | 48.0 | 4.10e-01 | 79.7% | 61.0% |
| 4od4A01 | 1.10.357.140 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase | 0.64 | 47.0 | 4.28e-01 | 76.3% | 77.6% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 51.0 | 5.17e-01 | 84.7% | 98.3% |
| 8gr7A01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.64 | 49.0 | 3.63e-01 | 82.2% | 72.6% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 45.0 | 3.46e-01 | 72.0% | 68.6% |
| 3b5oA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.64 | 45.0 | 3.62e-01 | 73.7% | 82.2% |
| 1sxjE03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.63 | 43.0 | 4.75e-01 | 70.3% | 93.8% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 49.0 | 4.64e-01 | 84.7% | 72.5% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.61 | 45.0 | 4.76e-01 | 76.3% | 100.0% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.61 | 49.0 | 4.14e-01 | 84.7% | 59.1% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 51.0 | 4.67e-01 | 92.4% | 96.2% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.61 | 46.0 | 4.24e-01 | 78.8% | 100.0% |
| 7sf8A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 48.0 | 3.79e-01 | 83.9% | 93.8% |
| 7eq1R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 48.0 | 3.70e-01 | 86.4% | 92.5% |
| 3fajA00 | 1.20.120.950 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 | 0.60 | 47.0 | 4.97e-01 | 87.3% | 98.0% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 47.0 | 4.45e-01 | 86.4% | 99.3% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.59 | 41.0 | 3.69e-01 | 70.3% | 62.8% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 38.0 | 4.08e-01 | 100.0% | 75.5% |
| 2zopA00 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.58 | 43.0 | 4.48e-01 | 79.7% | 83.9% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.58 | 43.0 | 4.53e-01 | 78.0% | 91.7% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.58 | 47.0 | 4.65e-01 | 89.0% | 98.4% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.57 | 44.0 | 4.00e-01 | 80.5% | 89.1% |
| 1g7dA00 | 1.20.1150.12 | Mainly Alpha › Up-down Bundle › Endoplasmic reticulum protein erp29 › Endoplasmic reticulum resident protein 29, C-terminal domain | 0.56 | 38.0 | 4.08e-01 | 70.3% | 79.2% |
| 8b70A01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.54 | 41.0 | 2.83e-01 | 80.5% | 75.1% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 37.0 | 3.74e-01 | 100.0% | 71.3% |
| 3o7qA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 48.0 | 4.04e-01 | 98.3% | 93.2% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 47.0 | 3.84e-01 | 98.3% | 90.8% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.53 | 37.0 | 3.83e-01 | 100.0% | 79.1% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.52 | 45.0 | 4.70e-01 | 97.5% | 97.3% |
ECOD (49)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3490690 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.83 | 65.0 | 6.38e-01 | 80.5% | 100.0% |
| 54386 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.83 | 63.0 | 5.39e-01 | 78.0% | 80.1% |
| 4020563 | 601.16.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › GIT1_C | 0.79 | 60.0 | 5.80e-01 | 78.8% | 85.4% |
| 3491587 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.79 | 60.0 | 3.43e-01 | 79.7% | 11.5% |
| 4093008 | 192.29.1.157 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › MG280 | 0.78 | 60.0 | 4.79e-01 | 79.7% | 97.3% |
| 4527343 | 141.1.1.3 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA | 0.78 | 57.0 | 4.17e-01 | 76.3% | 86.6% |
| 3205948 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.74 | 58.0 | 5.10e-01 | 83.1% | 78.3% |
| 5038395 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.74 | 56.0 | 5.16e-01 | 80.5% | 77.4% |
| 4383443 | 192.29.1.165 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29336 | 0.74 | 56.0 | 5.34e-01 | 80.5% | 99.3% |
| 4023032 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.74 | 56.0 | 4.36e-01 | 79.7% | 83.2% |
| 3192657 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.73 | 60.0 | 5.10e-01 | 86.4% | 73.5% |
| 4016004 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.73 | 57.0 | 4.97e-01 | 83.1% | 77.2% |
| 4013947 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.72 | 57.0 | 4.51e-01 | 84.7% | 62.9% |
| 3875142 | 601.11.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Perilipin | 0.72 | 64.0 | 5.04e-01 | 94.9% | 70.4% |
| 3931278 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.72 | 54.0 | 5.66e-01 | 79.7% | 90.7% |
| 3373206 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.72 | 55.0 | 4.04e-01 | 80.5% | 68.8% |
| 3463576 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.71 | 54.0 | 4.43e-01 | 80.5% | 72.7% |
| 3565707 | 601.11.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Perilipin | 0.71 | 63.0 | 5.30e-01 | 94.9% | 73.2% |
| 5054165 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.70 | 57.0 | 4.64e-01 | 88.1% | 55.5% |
| 3646445 | 3615.1.1.38 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › ROH1-like | 0.68 | 53.0 | 3.87e-01 | 82.2% | 65.5% |
| 3905731 | 601.11.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Perilipin | 0.66 | 60.0 | 4.85e-01 | 98.3% | 78.2% |
| 3685798 | 632.25.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › GBS CAMP factor N-terminal domain › GBS CAMP factor N-terminal domain | 0.66 | 49.0 | 4.30e-01 | 77.1% | 57.6% |
| 3616490 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 53.0 | 4.85e-01 | 84.7% | 74.7% |
| 5005799 | 5069.1.1.15 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm | 0.65 | 59.0 | 4.88e-01 | 100.0% | 74.3% |
| 3640223 | 109.3.1.179 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF7708 | 0.65 | 50.0 | 4.16e-01 | 80.5% | 71.7% |
| None | — | 0.65 | 50.0 | 3.37e-01 | 85.6% | 21.6% | |
| 3990409 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.64 | 48.0 | 4.38e-01 | 78.8% | 90.0% |
| 3617743 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.64 | 51.0 | 4.74e-01 | 83.9% | 77.2% |
| 3601571 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.63 | 50.0 | 4.70e-01 | 83.9% | 85.5% |
| 3368549 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.62 | 50.0 | 4.10e-01 | 87.3% | 69.5% |
| 3764098 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 42.0 | 3.65e-01 | 70.3% | 85.0% |
| 3577620 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 42.0 | 4.26e-01 | 100.0% | 73.9% |
| 5083937 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.59 | 53.0 | 4.30e-01 | 100.0% | 62.2% |
| 3214235 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.59 | 45.0 | 3.47e-01 | 82.2% | 75.9% |
| 4024396 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.59 | 47.0 | 4.48e-01 | 83.9% | 81.5% |
| 3407685 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.59 | 47.0 | 4.50e-01 | 84.7% | 96.3% |
| 5037027 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.58 | 44.0 | 4.12e-01 | 80.5% | 92.7% |
| 4960584 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.58 | 44.0 | 3.73e-01 | 80.5% | 62.4% |
| 5026989 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.58 | 46.0 | 3.70e-01 | 83.9% | 55.1% |
| 3576275 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.58 | 38.0 | 3.71e-01 | 86.4% | 61.5% |
| 4013285 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.58 | 40.0 | 3.12e-01 | 70.3% | 45.4% |
| 3463054 | 5050.1.1.108 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PUCC, Nodulin-like, NFD4_C | 0.56 | 47.0 | 3.10e-01 | 92.4% | 44.0% |
| 3516160 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 39.0 | 3.85e-01 | 100.0% | 66.9% |
| 3788506 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.54 | 39.0 | 3.68e-01 | 100.0% | 60.7% |
| 3969542 | 5051.1.1.0 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like | 0.53 | 46.0 | 3.24e-01 | 98.3% | 62.0% |
| 4076590 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.51 | 33.0 | 3.76e-01 | 84.7% | 86.7% |
| 5048128 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.51 | 42.0 | 3.10e-01 | 86.4% | 75.6% |
| 3334764 | 5059.1.1.24 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › PUNUT | 0.51 | 45.0 | 3.26e-01 | 100.0% | 64.9% |
| 5016147 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.51 | 42.0 | 4.03e-01 | 91.5% | 96.3% |
D4
high
residues 546-628
Domain cluster:
representative
CATH (38)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4r03A00 | 2.40.128.720 | Mainly Beta › Beta Barrel › Lipocalin › | 0.70 | 42.0 | 3.82e-01 | 73.5% | 45.9% |
| 6oziB00 | 3.30.2170.10 | Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily | 0.68 | 57.0 | 4.08e-01 | 91.6% | 83.0% |
| 4nspA00 | 3.30.2170.10 | Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily | 0.66 | 55.0 | 4.00e-01 | 92.8% | 34.9% |
| 8b0qA01 | 3.30.420.340 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › UvrC, RNAse H endonuclease domain | 0.63 | 53.0 | 4.25e-01 | 95.2% | 51.7% |
| 2w35A00 | 3.30.2170.10 | Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily | 0.61 | 49.0 | 3.70e-01 | 91.6% | 34.5% |
| 1yvuA04 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.60 | 51.0 | 3.83e-01 | 95.2% | 36.9% |
| 3r87A00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.59 | 41.0 | 3.48e-01 | 88.0% | 44.7% |
| 4obmA00 | 3.40.630.190 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein | 0.59 | 50.0 | 3.62e-01 | 97.6% | 32.9% |
| 3ndzE00 | 2.60.40.290 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.59 | 47.0 | 4.34e-01 | 86.7% | 100.0% |
| 4b60A02 | 2.60.40.1290 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.58 | 48.0 | 3.92e-01 | 90.4% | 93.6% |
| 1mu5A01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.58 | 39.0 | 2.96e-01 | 86.7% | 27.6% |
| 3cerC01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.58 | 50.0 | 4.36e-01 | 96.4% | 65.6% |
| 1fyhB02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.57 | 47.0 | 4.37e-01 | 89.2% | 95.1% |
| 3bf2A00 | 3.30.160.150 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain | 0.57 | 43.0 | 3.82e-01 | 81.9% | 70.4% |
| 5c0pA00 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.57 | 44.0 | 3.05e-01 | 83.1% | 54.6% |
| 2hzmB00 | 2.40.320.10 | Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 | 0.57 | 39.0 | 2.87e-01 | 72.3% | 84.1% |
| 8alzB04 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.57 | 48.0 | 4.38e-01 | 92.8% | 99.1% |
| 1gyvA00 | 2.60.40.1230 | Mainly Beta › Sandwich › Immunoglobulin-like › Gamma-adaptin ear (GAE) domain | 0.56 | 46.0 | 4.05e-01 | 89.2% | 89.2% |
| 2vzsA05 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 45.0 | 4.23e-01 | 89.2% | 97.0% |
| 1iz6A01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.56 | 32.0 | 3.46e-01 | 77.1% | 66.7% |
| 5m59A06 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.55 | 45.0 | 4.08e-01 | 89.2% | 94.6% |
| 6dnzA02 | 2.70.160.11 | Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 | 0.55 | 40.0 | 3.23e-01 | 79.5% | 82.0% |
| 2gtlN02 | 2.40.128.620 | Mainly Beta › Beta Barrel › Lipocalin › | 0.54 | 44.0 | 3.49e-01 | 89.2% | 60.0% |
| 2gtlO02 | 2.40.128.620 | Mainly Beta › Beta Barrel › Lipocalin › | 0.54 | 43.0 | 3.51e-01 | 88.0% | 61.3% |
| 5n1tA03 | 3.90.760.10 | Alpha Beta › Alpha-Beta Complex › Flavocytochrome C Sulfide Dehydrogenase; Chain A Domain 3 › Flavocytochrome c sulphide dehydrogenase, flavin-binding domain | 0.53 | 38.0 | 4.12e-01 | 75.9% | 88.7% |
| 3zx7A01 | 2.60.120.980 | Mainly Beta › Sandwich › Jelly Rolls › | 0.53 | 42.0 | 3.43e-01 | 85.5% | 86.2% |
| 3n54B01 | 6.20.190.10 | Special › Other non-globular › Nuclear Transport Factor 2; Chain: A, › Nutrient germinant receptor protein C, domain 1 | 0.53 | 36.0 | 4.01e-01 | 85.5% | 95.1% |
| 7kx7A03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.52 | 41.0 | 3.17e-01 | 89.2% | 95.3% |
| 3o6uC00 | 3.90.1010.20 | Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › | 0.52 | 42.0 | 3.80e-01 | 91.6% | 75.6% |
| 1vqqA01 | 3.10.450.100 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › NTF2-like; domain 1 | 0.51 | 34.0 | 3.21e-01 | 79.5% | 53.2% |
| 1b78A00 | 3.90.950.10 | Alpha Beta › Alpha-Beta Complex › Maf protein › | 0.51 | 41.0 | 3.26e-01 | 90.4% | 67.4% |
| 3fssA01 | 2.30.29.120 | Mainly Beta › Roll › PH-domain like › | 0.51 | 41.0 | 3.55e-01 | 89.2% | 60.3% |
| 3uh8A00 | 2.60.40.3350 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.51 | 40.0 | 3.64e-01 | 88.0% | 89.0% |
| 4gn2A00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.51 | 41.0 | 3.00e-01 | 90.4% | 32.9% |
| 5dstA02 | 2.70.160.11 | Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 | 0.51 | 36.0 | 2.93e-01 | 77.1% | 81.9% |
| 2q2eB01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.51 | 40.0 | 3.01e-01 | 88.0% | 68.3% |
| 4e3eA00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.50 | 37.0 | 2.47e-01 | 79.5% | 35.0% |
| 2uvaG09 | 2.40.128.700 | Mainly Beta › Beta Barrel › Lipocalin › | 0.50 | 36.0 | 3.31e-01 | 85.5% | 56.0% |
ECOD (78)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3240591 | 2484.1.1.43 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 | 0.71 | 59.0 | 4.17e-01 | 90.4% | 82.8% |
| 5070693 | 2484.1.1.22 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF99 | 0.70 | 53.0 | 4.15e-01 | 92.8% | 38.7% |
| 3604480 | 2484.1.1.22 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF99 | 0.69 | 54.0 | 4.25e-01 | 91.6% | 40.6% |
| 3672774 | 2484.1.1.43 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 | 0.69 | 58.0 | 4.58e-01 | 92.8% | 57.6% |
| 5043731 | 2484.1.1.122 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF2209 | 0.68 | 56.0 | 4.83e-01 | 90.4% | 60.0% |
| 2526821 | 2484.1.1.43 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 | 0.68 | 56.0 | 4.00e-01 | 90.4% | 81.6% |
| 3429580 | 2484.1.1.43 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 | 0.67 | 57.0 | 4.57e-01 | 92.8% | 63.1% |
| 3643562 | 2484.1.1.43 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 | 0.66 | 57.0 | 4.05e-01 | 95.2% | 38.8% |
| 3837099 | 2484.1.1.43 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 | 0.66 | 57.0 | 4.03e-01 | 95.2% | 37.3% |
| 3259935 | 2484.1.1.43 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 | 0.66 | 54.0 | 3.89e-01 | 91.6% | 80.2% |
| 5026406 | 2484.1.1.22 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF99 | 0.66 | 52.0 | 4.05e-01 | 92.8% | 39.4% |
| 5028451 | 2484.1.1.16 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_HII | 0.66 | 56.0 | 4.58e-01 | 95.2% | 68.4% |
| 2771373 | 2484.1.1.4 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H | 0.65 | 53.0 | 4.17e-01 | 90.4% | 44.4% |
| 3374455 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.64 | 50.0 | 3.45e-01 | 88.0% | 23.7% |
| 3609098 | 7575.1.1.0 ↗ | a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like | 0.64 | 57.0 | 3.28e-01 | 98.8% | 18.1% |
| 3255559 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.64 | 56.0 | 3.95e-01 | 98.8% | 34.0% |
| 3661619 | 192.18.1.0 ↗ | alpha bundles › Long alpha-hairpin › MxiH-like › MxiH-like | 0.63 | 52.0 | 3.79e-01 | 89.2% | 33.8% |
| 3457030 | 2484.1.1.106 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF659 | 0.63 | 49.0 | 3.70e-01 | 89.2% | 34.5% |
| 3505861 | 2484.1.1.204 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27046, PF27073 | 0.63 | 50.0 | 3.53e-01 | 88.0% | 27.1% |
| 3360123 | 192.18.1.0 ↗ | alpha bundles › Long alpha-hairpin › MxiH-like › MxiH-like | 0.63 | 50.0 | 3.14e-01 | 89.2% | 14.9% |
| 3232269 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.63 | 53.0 | 4.54e-01 | 92.8% | 81.5% |
| 3417357 | 2484.1.1.67 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 | 0.62 | 52.0 | 4.19e-01 | 94.0% | 46.7% |
| 5019749 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.62 | 51.0 | 4.30e-01 | 94.0% | 59.3% |
| 3226077 | 2484.1.1.50 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Dimer_Tnp_hAT | 0.61 | 50.0 | 3.12e-01 | 89.2% | 16.8% |
| 3517882 | 2484.1.1.215 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27041 | 0.61 | 49.0 | 3.13e-01 | 88.0% | 17.0% |
| 3846578 | 225.1.1.16 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › DUF4554 | 0.61 | 51.0 | 4.09e-01 | 90.4% | 72.5% |
| 3913349 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.61 | 49.0 | 3.12e-01 | 89.2% | 16.9% |
| 3664107 | 192.18.1.0 ↗ | alpha bundles › Long alpha-hairpin › MxiH-like › MxiH-like | 0.61 | 49.0 | 2.83e-01 | 89.2% | 8.9% |
| 3927366 | 2484.1.1.4 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H | 0.61 | 50.0 | 4.16e-01 | 91.6% | 52.7% |
| 3771977 | 2484.1.1.48 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II | 0.61 | 49.0 | 3.57e-01 | 98.8% | 31.7% |
| 2526820 | 2484.1.1.43 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 | 0.61 | 49.0 | 3.67e-01 | 91.6% | 34.2% |
| 3335943 | 2484.1.1.165 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.60 | 50.0 | 3.08e-01 | 94.0% | 15.0% |
| 3366390 | 2484.1.1.106 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF659 | 0.60 | 46.0 | 4.15e-01 | 89.2% | 58.3% |
| 3830643 | 2484.1.1.67 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 | 0.60 | 48.0 | 4.75e-01 | 92.8% | 82.2% |
| None | — | 0.60 | 50.0 | 4.15e-01 | 90.4% | 51.7% | |
| 3221272 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.60 | 53.0 | 3.84e-01 | 100.0% | 53.1% |
| 3427901 | 2484.1.1.215 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27041 | 0.60 | 48.0 | 3.56e-01 | 89.2% | 32.9% |
| 3481174 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.60 | 47.0 | 3.33e-01 | 88.0% | 31.1% |
| 4949601 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.60 | 50.0 | 4.86e-01 | 92.8% | 96.8% |
| 3783573 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.60 | 48.0 | 4.50e-01 | 88.0% | 99.0% |
| 3743256 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.59 | 50.0 | 4.52e-01 | 90.4% | 100.0% |
| 3427803 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.59 | 47.0 | 3.19e-01 | 89.2% | 21.8% |
| 3671250 | 2484.1.1.215 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27041 | 0.59 | 47.0 | 4.00e-01 | 89.2% | 51.0% |
| None | — | 0.59 | 47.0 | 3.07e-01 | 89.2% | 18.3% | |
| 3437776 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.59 | 47.0 | 2.96e-01 | 89.2% | 14.9% |
| 3787765 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.59 | 47.0 | 4.15e-01 | 88.0% | 99.2% |
| 3925547 | 2484.1.1.157 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF4371 | 0.59 | 47.0 | 3.65e-01 | 89.2% | 37.9% |
| 4223331 | 306.3.1.0 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like | 0.59 | 49.0 | 4.58e-01 | 92.8% | 98.1% |
| 3516180 | 2484.1.1.230 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27073 | 0.59 | 47.0 | 4.45e-01 | 89.2% | 72.1% |
| 3341563 | 2484.1.1.106 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF659 | 0.58 | 44.0 | 2.94e-01 | 89.2% | 18.2% |
| 3672945 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.58 | 46.0 | 3.43e-01 | 89.2% | 33.6% |
| 3527214 | 2484.1.1.204 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27046, PF27073 | 0.58 | 46.0 | 2.91e-01 | 89.2% | 15.4% |
| 3679012 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.58 | 46.0 | 3.26e-01 | 89.2% | 26.5% |
| 3508989 | 2484.1.1.230 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27073 | 0.58 | 45.0 | 3.79e-01 | 88.0% | 47.1% |
| 3457175 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.58 | 49.0 | 3.43e-01 | 92.8% | 30.0% |
| 3384667 | 2484.1.1.157 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF4371 | 0.58 | 45.0 | 2.92e-01 | 89.2% | 17.6% |
| 3923261 | 2484.1.1.230 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27073 | 0.57 | 46.0 | 4.12e-01 | 89.2% | 62.5% |
| 3531937 | 2484.1.1.317 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF28925 | 0.57 | 46.0 | 2.85e-01 | 89.2% | 15.5% |
| 3271756 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.57 | 47.0 | 3.81e-01 | 95.2% | 47.4% |
| 3421242 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.57 | 48.0 | 2.94e-01 | 94.0% | 17.2% |
| 3411385 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.57 | 47.0 | 3.68e-01 | 92.8% | 43.8% |
| 3169999 | 2484.1.1.48 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II | 0.56 | 46.0 | 3.70e-01 | 100.0% | 45.5% |
| 4024308 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.56 | 48.0 | 3.55e-01 | 96.4% | 70.0% |
| 1586 | 11.1.1.264 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_GlcNase | 0.56 | 45.0 | 4.00e-01 | 89.2% | 81.0% |
| 3940677 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.56 | 42.0 | 3.20e-01 | 86.7% | 34.4% |
| 3720242 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.55 | 45.0 | 4.00e-01 | 90.4% | 96.0% |
| 3541262 | 11.1.1.640 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ZP-N | 0.55 | 42.0 | 3.99e-01 | 83.1% | 89.0% |
| 4945556 | 11.1.5.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f | 0.55 | 45.0 | 3.49e-01 | 90.4% | 68.1% |
| 4928703 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.55 | 44.0 | 3.29e-01 | 89.2% | 72.3% |
| 5050811 | 2484.1.1.59 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA | 0.54 | 44.0 | 2.94e-01 | 92.8% | 88.7% |
| 3712567 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.53 | 42.0 | 3.32e-01 | 92.8% | 39.5% |
| 3415184 | 5090.1.1.0 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains | 0.53 | 43.0 | 3.09e-01 | 92.8% | 85.1% |
| 3444325 | 2484.1.1.106 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF659 | 0.53 | 45.0 | 3.58e-01 | 98.8% | 57.3% |
| 3589233 | 11.1.1.1182 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF29778 | 0.52 | 42.0 | 3.65e-01 | 90.4% | 81.5% |
| 4989872 | 2484.1.1.59 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA | 0.52 | 42.0 | 2.80e-01 | 92.8% | 90.9% |
| 3203065 | 719.1.1.0 ↗ | beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain | 0.51 | 41.0 | 3.45e-01 | 84.3% | 71.9% |
| 3727223 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.51 | 42.0 | 3.16e-01 | 90.4% | 82.3% |
| 3397042 | 3698.1.1.2 ↗ | beta sandwiches › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain › PRMT_C | 0.50 | 36.0 | 2.91e-01 | 77.1% | 81.1% |
D5
medium
residues 12-120
Domain cluster:
representative
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4akrA02 | 3.90.1150.210 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit | 0.68 | 56.0 | 5.06e-01 | 88.1% | 84.4% |
| 3aa0B02 | 3.90.1150.210 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit | 0.68 | 55.0 | 4.89e-01 | 87.2% | 83.2% |
| 1tkjA00 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.67 | 49.0 | 3.63e-01 | 96.3% | 30.0% |
| 2rs7A01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.61 | 40.0 | 4.74e-01 | 86.2% | 100.0% |
| 3gkeA02 | 3.90.380.10 | Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 | 0.59 | 47.0 | 3.77e-01 | 85.3% | 65.7% |
| 3ecrB03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.58 | 47.0 | 4.88e-01 | 94.5% | 92.2% |
| 1f49A05 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.58 | 47.0 | 3.40e-01 | 85.3% | 81.0% |
| 1ln1A00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.57 | 46.0 | 3.75e-01 | 85.3% | 67.5% |
| 3esiA00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.57 | 41.0 | 3.94e-01 | 74.3% | 92.7% |
| 3ke6B01 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.56 | 51.0 | 4.03e-01 | 100.0% | 93.7% |
| 3zt9A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.56 | 51.0 | 4.21e-01 | 100.0% | 96.4% |
| 4afkA00 | 2.40.160.100 | Mainly Beta › Beta Barrel › Porin › | 0.55 | 45.0 | 3.09e-01 | 90.8% | 60.2% |
| 3ehcB00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.55 | 39.0 | 3.78e-01 | 75.2% | 75.0% |
| 5do8B03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.54 | 30.0 | 3.49e-01 | 81.7% | 76.6% |
| 2pfcA00 | 3.10.129.30 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Rv0098, thioesterase-like hot dog domain | 0.54 | 39.0 | 3.43e-01 | 75.2% | 90.0% |
| 4jgwA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.53 | 33.0 | 2.94e-01 | 72.5% | 42.9% |
| 4h61A00 | 3.10.450.580 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Mediator complex, subunit Med6 | 0.53 | 37.0 | 3.48e-01 | 73.4% | 83.2% |
| 2rfrA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 38.0 | 3.46e-01 | 77.1% | 81.8% |
| 4id2A00 | 2.40.128.510 | Mainly Beta › Beta Barrel › Lipocalin › Protein of unknown function DUF4738 | 0.52 | 37.0 | 3.49e-01 | 74.3% | 90.4% |
| 3w42A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.51 | 44.0 | 3.71e-01 | 97.2% | 93.0% |
| 3t1oA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 42.0 | 3.53e-01 | 90.8% | 84.4% |
| 3g9kF01 | 3.60.20.40 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Gamma-glutamyltranspeptidase, small (S) subunit | 0.51 | 38.0 | 3.39e-01 | 79.8% | 98.2% |
| 1nnvA01 | 3.10.450.140 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › dsDNA mimic, putative | 0.50 | 36.0 | 3.78e-01 | 75.2% | 96.0% |
| 2ykfA02 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.50 | 36.0 | 3.28e-01 | 74.3% | 67.1% |
ECOD (51)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4929322 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.71 | 49.0 | 5.09e-01 | 85.3% | 76.0% |
| 3670595 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.70 | 45.0 | 4.85e-01 | 89.0% | 74.7% |
| 4975692 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.70 | 50.0 | 5.44e-01 | 97.2% | 90.0% |
| 3894031 | 330.1.1.6 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Staufen_C | 0.69 | 43.0 | 4.77e-01 | 89.0% | 80.0% |
| 3420092 | 330.1.1.1 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm | 0.68 | 43.0 | 4.92e-01 | 89.0% | 86.3% |
| 3809302 | 330.1.1.1 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm | 0.67 | 43.0 | 4.82e-01 | 89.0% | 83.5% |
| 3963053 | 2011.1.1.8 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 | 0.67 | 49.0 | 3.70e-01 | 96.3% | 33.7% |
| 3435911 | 330.1.1.1 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm | 0.67 | 42.0 | 4.22e-01 | 89.0% | 61.8% |
| 3243588 | 2484.1.1.200 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FTH | 0.65 | 43.0 | 3.08e-01 | 80.7% | 22.8% |
| 4026006 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.64 | 44.0 | 5.03e-01 | 83.5% | 95.0% |
| 3333293 | 330.1.1.1 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm | 0.63 | 39.0 | 4.48e-01 | 89.0% | 89.3% |
| 4008993 | 12.3.1.13 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C | 0.62 | 48.0 | 3.49e-01 | 80.7% | 85.2% |
| 3658256 | 708.1.1.1 ↗ | beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › NAM | 0.62 | 44.0 | 3.73e-01 | 74.3% | 77.2% |
| 4673646 | 331.3.1.19 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › VanA_C | 0.61 | 48.0 | 3.83e-01 | 84.4% | 65.9% |
| 3251350 | 867.1.1.1 ↗ | a+b three layers › Coproporphyrinogen III oxidase › Coproporphyrinogen III oxidase › Coproporphyrinogen III oxidase › Coprogen_oxidas | 0.61 | 53.0 | 3.81e-01 | 96.3% | 71.6% |
| 3276086 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.60 | 50.0 | 4.27e-01 | 88.1% | 79.4% |
| 3229636 | 331.3.1.6 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PRELI | 0.60 | 49.0 | 4.15e-01 | 88.1% | 72.4% |
| 4947567 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.60 | 49.0 | 3.23e-01 | 88.1% | 93.8% |
| 5069317 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.60 | 50.0 | 3.32e-01 | 89.0% | 92.0% |
| 4028363 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.60 | 45.0 | 4.97e-01 | 80.7% | 95.6% |
| 4320633 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.60 | 49.0 | 3.24e-01 | 88.1% | 93.0% |
| 2858695 | 331.3.1.19 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › VanA_C | 0.60 | 47.0 | 3.63e-01 | 84.4% | 55.9% |
| 3802643 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.60 | 46.0 | 4.87e-01 | 95.4% | 91.6% |
| 5029795 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.59 | 49.0 | 3.35e-01 | 88.1% | 91.7% |
| 5073876 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.59 | 48.0 | 3.17e-01 | 88.1% | 92.8% |
| 3592741 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.59 | 38.0 | 4.16e-01 | 85.3% | 82.4% |
| 4083442 | 2011.1.1.6 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 | 0.59 | 54.0 | 3.97e-01 | 99.1% | 40.0% |
| 4000635 | 331.3.1.6 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PRELI | 0.59 | 49.0 | 4.17e-01 | 90.8% | 76.7% |
| 5052250 | 12.3.1.15 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › AmyA-gluTrfs_C | 0.59 | 45.0 | 3.30e-01 | 80.7% | 91.3% |
| 3428134 | 243.3.1.19 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › DUF3615 | 0.59 | 42.0 | 4.38e-01 | 73.4% | 93.0% |
| 3554870 | 331.3.1.3 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START | 0.58 | 47.0 | 3.78e-01 | 85.3% | 66.8% |
| 3812918 | 331.3.1.43 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PDF2_C | 0.58 | 46.0 | 3.66e-01 | 84.4% | 66.8% |
| 4023996 | 331.3.1.6 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PRELI | 0.58 | 48.0 | 4.10e-01 | 90.8% | 77.8% |
| 5045683 | 2011.1.1.8 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 | 0.56 | 46.0 | 3.38e-01 | 100.0% | 33.7% |
| 3742761 | 243.1.1.41 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › Coa1 | 0.56 | 43.0 | 4.24e-01 | 79.8% | 79.1% |
| 3843014 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.56 | 40.0 | 4.08e-01 | 73.4% | 83.8% |
| 3171491 | 883.1.1.20 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › SMP_MUG190-like | 0.56 | 42.0 | 3.39e-01 | 77.1% | 83.4% |
| 3633144 | 3435.1.1.2 ↗ | a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC › CENP-N | 0.55 | 45.0 | 3.75e-01 | 87.2% | 69.7% |
| 5048348 | 3080.1.1.0 ↗ | a+b complex topology › Necrosis and ethylene-inducing peptide 1-like proteins › Necrosis and ethylene-inducing peptide 1-like proteins › Necrosis and ethylene-inducing peptide 1-like proteins | 0.55 | 46.0 | 3.77e-01 | 90.8% | 75.5% |
| 3428522 | 331.3.1.43 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PDF2_C | 0.55 | 44.0 | 3.46e-01 | 88.1% | 68.3% |
| 4932706 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.54 | 48.0 | 3.02e-01 | 97.2% | 89.9% |
| 3326226 | 331.10.2.0 ↗ | a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase | 0.54 | 44.0 | 3.91e-01 | 88.1% | 65.8% |
| 4963648 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.53 | 47.0 | 3.08e-01 | 99.1% | 83.1% |
| 4139499 | 2004.1.1.293 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 | 0.53 | 47.0 | 3.02e-01 | 99.1% | 82.2% |
| 3743703 | 883.1.1.20 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › SMP_MUG190-like | 0.53 | 40.0 | 3.28e-01 | 81.7% | 76.2% |
| 224067 | 6098.1.1.1 ↗ | a+b two layers › BACOVA_05496-like › BACOVA_05496-like › BACOVA_05496-like › DUF4738 | 0.52 | 37.0 | 3.49e-01 | 74.3% | 90.4% |
| 3729993 | 243.1.1.28 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF4440 | 0.52 | 37.0 | 3.48e-01 | 72.5% | 95.4% |
| 3350254 | 7579.1.1.42 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4 | 0.52 | 41.0 | 3.09e-01 | 86.2% | 89.5% |
| 3690324 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.51 | 37.0 | 3.39e-01 | 73.4% | 89.3% |
| 3016538 | 7579.1.1.0 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases | 0.51 | 43.0 | 3.28e-01 | 93.6% | 80.7% |
| 3291183 | 2011.1.1.6 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 | 0.50 | 44.0 | 3.27e-01 | 100.0% | 36.7% |
D6
medium
residues 124-181
Domain cluster:
representative
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3cz8A02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.66 | 50.0 | 5.09e-01 | 84.5% | 100.0% |
| 3vb0A01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.66 | 50.0 | 3.93e-01 | 84.5% | 88.4% |
| 4ha8A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.65 | 43.0 | 4.26e-01 | 77.6% | 63.5% |
| 4esnA00 | 2.60.320.10 | Mainly Beta › Sandwich › mini-chromosome maintenance (MCM) complex, domain 2 › N-utilization substance G protein NusG, insert domain | 0.64 | 52.0 | 4.73e-01 | 89.7% | 94.9% |
| 1wi9A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 42.0 | 4.23e-01 | 77.6% | 70.7% |
| 1xhcA03 | 3.30.390.30 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain | 0.62 | 34.0 | 3.67e-01 | 89.7% | 62.5% |
| 2qyvA01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.59 | 46.0 | 3.03e-01 | 87.9% | 43.4% |
| 4haoA02 | 2.60.200.30 | Mainly Beta › Sandwich › Tumour Suppressor Smad4 › Probable inorganic polyphosphate/atp-NAD kinase; domain 2 | 0.58 | 47.0 | 3.66e-01 | 91.4% | 97.0% |
| 2e5aA01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.55 | 42.0 | 2.84e-01 | 84.5% | 39.4% |
| 2l4mA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 37.0 | 3.55e-01 | 77.6% | 59.4% |
| 4pxcA01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.55 | 44.0 | 2.80e-01 | 91.4% | 31.0% |
| 3p1aA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.54 | 42.0 | 3.52e-01 | 89.7% | 92.0% |
| 3e99A00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 45.0 | 3.45e-01 | 96.6% | 83.1% |
| 2cw8A01 | 2.170.16.10 | Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain | 0.53 | 44.0 | 3.24e-01 | 96.6% | 94.7% |
| 2wshA00 | 3.40.1440.40 | Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › | 0.53 | 47.0 | 3.58e-01 | 100.0% | 50.7% |
| 1hx6A02 | 2.60.120.20 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 44.0 | 3.34e-01 | 96.6% | 51.8% |
| 1sb7A02 | 3.30.2340.10 | Alpha Beta › 2-Layer Sandwich › Pseudouridine synthase › TruD, insertion domain | 0.52 | 38.0 | 3.01e-01 | 82.8% | 85.3% |
| 1ne6A01 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.51 | 43.0 | 3.50e-01 | 100.0% | 53.3% |
| 2vugA02 | 3.30.1490.70 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › | 0.51 | 44.0 | 4.16e-01 | 96.6% | 87.5% |
| 3tx8A02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 37.0 | 3.03e-01 | 79.3% | 90.4% |
| 1hx6B01 | 2.70.9.30 | Mainly Beta › Distorted Sandwich › Adenovirus Type 2 Hexon; domain 4 › Viral coat protein p3 | 0.51 | 43.0 | 2.93e-01 | 98.3% | 44.2% |
| 2vvfA02 | 2.60.120.730 | Mainly Beta › Sandwich › Jelly Rolls › | 0.50 | 42.0 | 3.35e-01 | 96.6% | 55.5% |
| 2dmwA01 | 3.30.450.50 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Longin domain | 0.50 | 41.0 | 3.29e-01 | 91.4% | 53.4% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4427421 | 3529.1.1.6 ↗ | beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Band_7 | 0.69 | 44.0 | 4.86e-01 | 100.0% | 84.4% |
| 4115593 | 2002.1.1.30 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_18 | 0.69 | 56.0 | 3.48e-01 | 91.4% | 18.8% |
| 3273832 | 3529.1.1.6 ↗ | beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Band_7 | 0.68 | 44.0 | 5.04e-01 | 100.0% | 95.0% |
| 3624164 | 331.23.1.8 ↗ | a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain › Gemin6_C | 0.68 | 46.0 | 4.34e-01 | 89.7% | 58.6% |
| 3300493 | 2004.1.1.26 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin | 0.67 | 52.0 | 3.79e-01 | 89.7% | 75.6% |
| 3343541 | 3529.1.1.0 ↗ | beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain | 0.66 | 43.0 | 4.80e-01 | 100.0% | 88.9% |
| 4958377 | 822.1.1.2 ↗ | a+b two layers › GYF/BRK domain-like › GYF domain › GYF domain › GYF_2 | 0.65 | 42.0 | 4.53e-01 | 91.4% | 79.2% |
| 3642725 | 3529.1.1.0 ↗ | beta sandwiches › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain › Major vault protein (MVP) structural repeat domain | 0.65 | 43.0 | 4.07e-01 | 100.0% | 57.1% |
| 5078972 | 331.10.2.0 ↗ | a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase | 0.65 | 47.0 | 4.17e-01 | 77.6% | 58.8% |
| 4976589 | 331.10.2.0 ↗ | a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase | 0.65 | 47.0 | 3.99e-01 | 77.6% | 53.7% |
| 3429762 | 230.5.1.0 ↗ | a+b two layers › T-fold › Band 7/SPFH domain › Band 7/SPFH domain | 0.63 | 41.0 | 4.62e-01 | 100.0% | 97.5% |
| 3481499 | 223.1.1.119 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › Intu_longin_2 | 0.59 | 54.0 | 3.86e-01 | 100.0% | 68.4% |
| 3623367 | 376.1.1.22 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4_3 | 0.57 | 50.0 | 4.27e-01 | 100.0% | 81.1% |
| 3289183 | 3837.1.1.3 ↗ | alpha bundles › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › DUF7873 | 0.57 | 46.0 | 3.33e-01 | 93.1% | 87.8% |
| 3531612 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.56 | 37.0 | 3.33e-01 | 100.0% | 50.0% |
| 3392216 | 223.2.1.31 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_2 | 0.55 | 47.0 | 3.23e-01 | 93.1% | 41.6% |
| 3988217 | 241.12.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › YktB/PF0168-like › YktB/PF0168-like | 0.55 | 40.0 | 2.83e-01 | 100.0% | 23.0% |
| 3634309 | 304.11.1.1 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Acyl_transf_1 | 0.54 | 41.0 | 3.15e-01 | 84.5% | 75.9% |
| 3267216 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.54 | 40.0 | 3.37e-01 | 82.8% | 87.6% |
| 3890078 | 4357.1.1.2 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE_1 | 0.53 | 42.0 | 3.80e-01 | 91.4% | 75.3% |
| 3775421 | 223.2.1.31 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_2 | 0.53 | 48.0 | 3.29e-01 | 100.0% | 55.8% |
| 5051542 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.53 | 43.0 | 3.02e-01 | 91.4% | 33.7% |
| 3213272 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.52 | 36.0 | 2.00e-01 | 74.1% | 15.8% |
| 4943244 | 69.1.1.0 ↗ | beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint | 0.51 | 42.0 | 3.10e-01 | 96.6% | 95.9% |
| 4928633 | 101.1.2.18 ↗ | alpha arrays › HTH › HTH › winged helix domain › Ribosomal_S19e | 0.51 | 39.0 | 3.25e-01 | 84.5% | 50.5% |
| 3336122 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.50 | 36.0 | 3.00e-01 | 82.8% | 86.4% |
| 4251107 | 321.1.1.6 ↗ | a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › Pup_ligase | 0.50 | 43.0 | 2.59e-01 | 96.6% | 51.4% |