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MN234216.1__QFG13322.1__SEA_GILGAMESH_130__00130

Bact-Vir

MN234216.1__QFG13322.1__SEA_GILGAMESH_130__00130

Identity

Accession:
MN234216 ↗
Kingdom:
phage

Quality

91.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-102
PDB
Domain cluster: representative
CATH (62)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.81 72.0 6.33e-01 96.1% 74.1%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.81 72.0 6.26e-01 96.1% 72.2%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.77 58.0 5.31e-01 78.4% 69.5%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.77 60.0 5.71e-01 81.4% 79.0%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.76 67.0 6.33e-01 96.1% 95.1%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.76 59.0 4.75e-01 82.4% 55.0%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.75 62.0 6.08e-01 88.2% 91.8%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 60.0 4.33e-01 84.3% 81.5%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 63.0 5.98e-01 91.2% 95.0%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 57.0 5.02e-01 82.4% 96.7%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.74 64.0 5.69e-01 96.1% 75.0%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 58.0 4.85e-01 84.3% 85.1%
5tj5E00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.74 57.0 5.17e-01 82.4% 78.3%
2fzfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.73 56.0 4.94e-01 81.4% 94.7%
4omfA00 1.10.645.10 Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B 0.73 64.0 4.29e-01 96.1% 54.5%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.72 59.0 4.43e-01 87.3% 84.5%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.72 54.0 4.56e-01 78.4% 58.4%
6o7uc01 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.72 55.0 4.51e-01 81.4% 61.1%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 57.0 4.16e-01 84.3% 83.6%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 59.0 4.66e-01 89.2% 90.5%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.71 59.0 5.67e-01 90.2% 94.8%
1i5nB00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.71 50.0 4.68e-01 77.5% 59.7%
3ay5A02 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.71 60.0 5.19e-01 95.1% 66.1%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 56.0 4.26e-01 86.3% 81.8%
3pt1A02 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.70 56.0 5.27e-01 84.3% 100.0%
4mudC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 62.0 4.80e-01 96.1% 77.3%
3d19B00 1.20.1260.120 Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 0.70 60.0 4.52e-01 97.1% 95.0%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 54.0 4.76e-01 83.3% 99.3%
6k6iA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.69 60.0 4.69e-01 95.1% 62.1%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.69 57.0 5.87e-01 87.3% 97.9%
1at9A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.69 61.0 4.69e-01 97.1% 52.2%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.69 55.0 5.09e-01 85.3% 72.1%
2okuA00 1.20.120.470 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain 0.69 53.0 5.00e-01 82.4% 76.2%
1dkxA02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.68 49.0 5.36e-01 86.3% 96.2%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 51.0 4.73e-01 80.4% 65.4%
2lmgA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.68 47.0 5.32e-01 78.4% 98.6%
2uxwA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.66 57.0 4.75e-01 97.1% 68.8%
1eb6A00 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.65 57.0 4.73e-01 94.1% 93.2%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.65 55.0 3.87e-01 93.1% 79.8%
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.65 46.0 5.14e-01 80.4% 100.0%
2g2dA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.65 55.0 4.66e-01 90.2% 71.2%
3ez0C00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 55.0 4.39e-01 96.1% 81.2%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 55.0 4.98e-01 99.0% 92.3%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 53.0 4.29e-01 97.1% 81.4%
6fjxA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.61 51.0 3.71e-01 88.2% 51.7%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.61 48.0 4.41e-01 91.2% 65.4%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.60 54.0 4.18e-01 98.0% 88.7%
3i1aA03 1.20.58.840 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 46.0 4.48e-01 83.3% 81.9%
5cy5B00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.59 49.0 4.35e-01 91.2% 71.1%
3pqaB01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.59 49.0 3.61e-01 90.2% 51.1%
3c1yA02 1.20.1260.110 Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region 0.59 46.0 4.06e-01 83.3% 94.6%
2hg2A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.58 49.0 3.51e-01 90.2% 49.3%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.58 50.0 4.06e-01 97.1% 65.8%
3op0A01 1.20.930.20 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain 0.58 48.0 4.34e-01 88.2% 87.5%
2y51A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.57 47.0 3.41e-01 92.2% 48.1%
4gdxA02 1.10.246.130 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain 0.55 39.0 3.79e-01 71.6% 75.7%
5mi7A03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.55 46.0 3.38e-01 90.2% 43.6%
4pt1B00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.54 35.0 3.29e-01 86.3% 50.8%
1k74D00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.54 45.0 3.36e-01 93.1% 97.1%
8e9gJ01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.52 39.0 3.37e-01 84.3% 47.9%
2k3nA00 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.51 41.0 3.62e-01 93.1% 58.1%
2h5gB01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.51 42.0 3.17e-01 94.1% 51.6%
ECOD (86)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5024573 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.88 71.0 6.05e-01 84.3% 96.1%
3644752 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.83 75.0 6.36e-01 96.1% 90.6%
3802170 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.83 75.0 6.47e-01 96.1% 73.3%
3835373 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.83 73.0 6.36e-01 95.1% 72.0%
3427223 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.82 74.0 6.29e-01 95.1% 70.3%
4467968 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.81 62.0 5.80e-01 78.4% 72.5%
4383079 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.81 72.0 6.20e-01 96.1% 70.3%
3301502 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.80 73.0 6.31e-01 97.1% 91.3%
3445971 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.80 72.0 5.77e-01 97.1% 72.1%
3312398 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.79 70.0 5.90e-01 96.1% 67.9%
3728988 3567.1.1.82 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Frag1 0.78 67.0 5.12e-01 92.2% 70.7%
3548233 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.78 69.0 5.86e-01 97.1% 89.1%
3466334 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.77 68.0 6.24e-01 95.1% 86.2%
3826910 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.77 68.0 5.83e-01 96.1% 72.5%
3171132 5001.1.1.115 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Frag1 0.77 67.0 4.84e-01 94.1% 71.9%
3236503 5059.1.1.3 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT 0.76 53.0 3.55e-01 70.6% 63.1%
3991803 5059.1.1.34 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA, Nuc_sug_transp 0.76 53.0 3.63e-01 70.6% 70.0%
3408518 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.76 66.0 6.14e-01 93.1% 86.4%
3296913 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.76 67.0 5.73e-01 96.1% 68.1%
3393338 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.75 69.0 5.93e-01 99.0% 83.0%
3542652 633.23.1.34 alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 0.75 66.0 5.51e-01 95.1% 81.8%
3784936 5069.1.1.38 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Frag1 0.75 65.0 4.80e-01 94.1% 66.9%
3513593 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.75 65.0 5.55e-01 92.2% 81.3%
4935725 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.75 58.0 5.25e-01 81.4% 67.4%
3485403 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.75 61.0 4.95e-01 86.3% 87.4%
3826788 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.75 65.0 5.48e-01 96.1% 69.9%
3498332 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.74 63.0 5.52e-01 91.2% 93.3%
3812846 633.15.1.1 alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N › BCDHK_Adom3 0.74 65.0 5.56e-01 96.1% 76.9%
3360270 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.74 58.0 4.76e-01 83.3% 52.8%
3865873 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.74 65.0 5.57e-01 96.1% 80.6%
3911582 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.74 64.0 5.62e-01 95.1% 93.3%
3536246 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.74 64.0 5.64e-01 94.1% 89.0%
3873872 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.73 66.0 5.54e-01 98.0% 84.7%
3905854 633.15.1.1 alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N › BCDHK_Adom3 0.73 64.0 5.47e-01 96.1% 73.3%
3909550 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.73 63.0 5.61e-01 94.1% 89.0%
3973500 601.1.2.144 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HBM 0.73 59.0 5.67e-01 86.3% 93.9%
3233225 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.72 64.0 4.54e-01 96.1% 89.5%
3373991 5001.1.1.10 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Ceramidase 0.70 61.0 4.71e-01 96.1% 86.1%
3631036 5069.1.1.38 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Frag1 0.70 61.0 5.10e-01 97.1% 90.6%
3685068 5059.1.1.16 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › SLC35F 0.70 48.0 3.39e-01 71.6% 64.1%
3899721 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.70 61.0 5.21e-01 96.1% 89.1%
5070606 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.69 62.0 5.60e-01 97.1% 94.8%
3824444 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.69 60.0 4.65e-01 96.1% 84.8%
3701078 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.69 60.0 5.50e-01 96.1% 83.7%
3692081 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.69 62.0 5.45e-01 100.0% 92.7%
3247271 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.68 59.0 4.32e-01 96.1% 89.1%
5082452 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.68 60.0 4.47e-01 97.1% 89.8%
3207001 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.68 58.0 5.27e-01 95.1% 88.6%
3285823 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.67 57.0 5.11e-01 96.1% 88.3%
3216428 5001.1.1.28 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Per1 0.66 58.0 4.22e-01 97.1% 79.3%
4940075 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.66 49.0 5.34e-01 78.4% 98.8%
5084053 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.66 59.0 4.47e-01 97.1% 93.5%
3750717 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.65 55.0 4.04e-01 92.2% 84.7%
3800846 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.65 52.0 3.54e-01 83.3% 74.2%
3183536 5001.1.1.10 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Ceramidase 0.65 56.0 4.08e-01 94.1% 76.8%
3381284 5059.1.1.33 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA, SLC35F 0.65 53.0 3.71e-01 87.3% 75.7%
4062149 632.7.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.65 52.0 5.12e-01 88.2% 80.9%
3170645 5001.1.1.28 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Per1 0.65 56.0 4.25e-01 95.1% 91.0%
3535849 5059.1.1.4 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Nuc_sug_transp 0.65 49.0 3.43e-01 79.4% 89.5%
4479748 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.64 48.0 5.10e-01 83.3% 90.0%
3250373 5059.1.1.5 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA 0.64 49.0 3.43e-01 81.4% 91.2%
3825995 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.64 53.0 3.76e-01 89.2% 76.7%
3867833 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.64 57.0 4.05e-01 97.1% 92.9%
5046568 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.64 56.0 4.71e-01 96.1% 68.8%
3912736 5001.1.1.18 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF3522 0.64 56.0 4.43e-01 98.0% 88.8%
3665854 5059.1.1.16 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › SLC35F 0.63 53.0 3.67e-01 90.2% 75.5%
56635 150.2.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Cobalamin adenosyltransferase › Cobalamin adenosyltransferase 0.63 56.0 4.84e-01 97.1% 68.6%
3276380 5059.1.1.5 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA 0.62 52.0 3.55e-01 90.2% 67.0%
3393571 5059.1.1.4 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Nuc_sug_transp 0.62 51.0 3.56e-01 87.3% 76.5%
3964803 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.62 52.0 3.74e-01 90.2% 77.2%
3228505 5059.1.1.34 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA, Nuc_sug_transp 0.62 52.0 3.62e-01 89.2% 76.6%
4022479 5059.1.1.6 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › CSG2 0.62 51.0 3.48e-01 90.2% 78.9%
3598200 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.61 51.0 3.59e-01 89.2% 80.3%
4085781 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.61 50.0 3.62e-01 90.2% 80.7%
4014870 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.59 52.0 4.63e-01 95.1% 90.0%
3679794 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.58 48.0 3.52e-01 91.2% 81.4%
4945209 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.58 49.0 3.49e-01 93.1% 81.3%
3554703 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.58 49.0 3.55e-01 96.1% 55.2%
3419649 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.56 47.0 4.58e-01 94.1% 93.0%
3194380 5059.1.1.4 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Nuc_sug_transp 0.56 48.0 3.27e-01 94.1% 57.7%
3217897 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.55 42.0 4.04e-01 82.4% 97.5%
54358 4266.1.1.0 alpha bundles › Hyaluronidase domain-like › Hyaluronidase post-catalytic domain-like › Hyaluronidase post-catalytic domain-like 0.54 46.0 4.01e-01 91.2% 74.7%
2705299 4266.1.1.4 alpha bundles › Hyaluronidase domain-like › Hyaluronidase post-catalytic domain-like › Hyaluronidase post-catalytic domain-like › Glyco_hydro_84_hel 0.54 46.0 3.98e-01 91.2% 73.2%
4948074 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.54 45.0 3.26e-01 94.1% 69.2%
3250479 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.51 37.0 2.92e-01 75.5% 61.4%
3819669 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.50 42.0 3.08e-01 97.1% 68.4%
D2 medium residues 103-179
PDB
Domain cluster: representative
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.88 69.0 6.96e-01 81.8% 89.6%
3fd9A03 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.87 68.0 7.00e-01 81.8% 84.9%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.84 65.0 6.46e-01 81.8% 92.6%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.83 59.0 6.16e-01 74.0% 90.1%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.83 63.0 5.82e-01 81.8% 64.9%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 63.0 6.62e-01 81.8% 87.3%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.82 60.0 6.00e-01 76.6% 76.9%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.81 74.0 6.07e-01 100.0% 74.6%
2kw6A00 6.10.140.1300 Special › Helix non-globular › Helix Hairpins › 0.80 55.0 6.00e-01 75.3% 84.6%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.80 67.0 5.92e-01 89.6% 84.5%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.78 59.0 6.33e-01 80.5% 92.5%
7ymiZ01 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.78 54.0 6.04e-01 71.4% 94.8%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.77 68.0 5.50e-01 97.4% 67.1%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.77 68.0 5.50e-01 97.4% 67.1%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.76 58.0 5.51e-01 80.5% 75.6%
1lqsL01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.75 51.0 4.63e-01 70.1% 55.0%
3tulB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.74 65.0 5.43e-01 98.7% 97.7%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.74 58.0 5.09e-01 83.1% 83.5%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.73 64.0 5.21e-01 96.1% 70.4%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.73 53.0 5.73e-01 80.5% 93.8%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.72 54.0 5.26e-01 80.5% 74.1%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.72 50.0 4.99e-01 74.0% 72.8%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 57.0 5.81e-01 88.3% 92.1%
2uuiA00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.71 62.0 4.97e-01 100.0% 60.0%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.71 50.0 4.93e-01 77.9% 69.5%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 60.0 4.82e-01 96.1% 66.4%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.69 57.0 4.82e-01 92.2% 71.3%
1bhaA00 1.10.287.170 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 49.0 5.18e-01 75.3% 95.5%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.67 43.0 4.36e-01 81.8% 65.4%
1jm6B02 1.20.140.20 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain 0.65 54.0 4.42e-01 96.1% 59.9%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.65 48.0 4.93e-01 83.1% 83.8%
2mpnA00 6.10.140.1340 Special › Helix non-globular › Helix Hairpins › 0.65 47.0 4.89e-01 77.9% 89.7%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 54.0 4.73e-01 96.1% 83.1%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.65 56.0 4.55e-01 100.0% 78.2%
1n5uA02 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.64 52.0 4.94e-01 88.3% 87.8%
1zbtA01 6.10.140.1950 Special › Helix non-globular › Helix Hairpins › 0.64 51.0 5.00e-01 88.3% 94.0%
1kxpD04 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.61 48.0 4.85e-01 87.0% 98.7%
1vibA00 1.10.287.120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like 0.59 39.0 4.50e-01 70.1% 96.4%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.57 41.0 3.53e-01 79.2% 48.2%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4882209 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.89 66.0 6.35e-01 77.9% 69.4%
3780651 3602.1.1.0 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.85 63.0 6.91e-01 77.9% 95.4%
4214525 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.83 74.0 6.67e-01 94.8% 99.0%
4012236 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.83 74.0 5.72e-01 96.1% 71.2%
4561291 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.83 76.0 6.71e-01 97.4% 97.1%
3355246 192.1.1.0 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.82 63.0 6.29e-01 80.5% 77.5%
4033482 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.82 61.0 5.76e-01 77.9% 67.8%
3597345 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.82 64.0 5.53e-01 83.1% 68.7%
2663455 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.80 63.0 6.68e-01 83.1% 95.6%
3380124 109.4.1.1266 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm, ARM_PUB 0.80 60.0 3.78e-01 80.5% 16.7%
4011664 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.79 72.0 5.17e-01 100.0% 73.3%
3479389 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.79 65.0 4.81e-01 88.3% 64.3%
3973458 611.4.1.2 alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like › Acyl-CoA_dh_C 0.78 65.0 5.45e-01 92.2% 66.2%
3929573 192.8.1.395 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › CHDCT2 0.78 64.0 6.17e-01 87.0% 98.8%
5048328 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.77 58.0 5.80e-01 80.5% 80.0%
4968618 611.6.1.0 alpha bundles › N-cbl like › PT26-6P helical domain › PT26-6P helical domain 0.77 69.0 6.36e-01 98.7% 94.9%
4957093 3456.1.1.1 extended segments › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › Oxidored_q4 0.75 57.0 4.85e-01 80.5% 54.6%
3543090 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.74 57.0 5.18e-01 83.1% 63.8%
4214655 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.74 56.0 5.59e-01 81.8% 80.0%
3559937 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 55.0 4.99e-01 81.8% 62.9%
4227021 5045.1.1.1 alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A 0.69 59.0 4.30e-01 100.0% 53.6%
5008017 601.30.1.1 alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.68 59.0 4.95e-01 100.0% 82.9%
4648665 632.7.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.66 57.0 5.60e-01 98.7% 95.3%
3809254 509.1.1.1 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH 0.66 43.0 4.67e-01 74.0% 80.0%
3809006 5050.1.1.15 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like 0.61 52.0 3.59e-01 98.7% 89.3%
3674630 5050.1.1.15 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like 0.54 49.0 3.30e-01 100.0% 61.4%
3921200 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.54 39.0 3.44e-01 81.8% 51.5%