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MN270278.1__QGJ86613.1__X__00048
Bact-VirMN270278.1__QGJ86613.1__X__00048
Identity
- Accession:
- MN270278 ↗
- Kingdom:
- phage
Quality
87.6
mean pLDDT
Taxonomy
TaxID: 2664408
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 28-148
Domain cluster:
representative
CATH (68)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.77 | 47.0 | 4.43e-01 | 89.3% | 51.8% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.76 | 62.0 | 6.28e-01 | 95.9% | 88.2% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 62.0 | 5.15e-01 | 93.4% | 79.0% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.72 | 59.0 | 5.63e-01 | 99.2% | 74.1% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.71 | 47.0 | 5.45e-01 | 91.7% | 96.4% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.71 | 56.0 | 5.32e-01 | 94.2% | 71.1% |
| 6zhiB02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.71 | 46.0 | 5.41e-01 | 87.6% | 96.4% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.71 | 65.0 | 5.66e-01 | 100.0% | 84.4% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.71 | 52.0 | 5.38e-01 | 99.2% | 81.7% |
| 3ripA02 | 1.20.120.1900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain | 0.70 | 61.0 | 4.57e-01 | 91.7% | 47.0% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.70 | 47.0 | 4.64e-01 | 95.0% | 64.8% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.69 | 55.0 | 5.60e-01 | 96.7% | 85.6% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.69 | 51.0 | 5.28e-01 | 87.6% | 81.0% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.69 | 51.0 | 5.52e-01 | 76.0% | 97.1% |
| 1sxjE03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.69 | 39.0 | 4.35e-01 | 85.1% | 69.1% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.69 | 60.0 | 4.75e-01 | 94.2% | 84.5% |
| 4rm7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 54.0 | 5.17e-01 | 91.7% | 72.7% |
| 1st6A01 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.68 | 61.0 | 4.74e-01 | 99.2% | 45.9% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.68 | 49.0 | 5.13e-01 | 81.8% | 82.7% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.67 | 58.0 | 5.24e-01 | 93.4% | 88.8% |
| 4wjg400 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.67 | 58.0 | 4.52e-01 | 95.0% | 82.8% |
| 8cdaB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 58.0 | 5.28e-01 | 95.0% | 79.2% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.66 | 44.0 | 5.15e-01 | 87.6% | 100.0% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.66 | 57.0 | 4.98e-01 | 100.0% | 61.3% |
| 1xioA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 61.0 | 4.95e-01 | 100.0% | 97.7% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.66 | 54.0 | 4.96e-01 | 91.7% | 68.6% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.66 | 47.0 | 4.92e-01 | 89.3% | 82.4% |
| 2yn7A00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.66 | 58.0 | 4.79e-01 | 96.7% | 80.8% |
| 6ygiB01 | 1.10.4090.10 | Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus | 0.65 | 50.0 | 4.71e-01 | 80.2% | 67.8% |
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.65 | 56.0 | 5.12e-01 | 99.2% | 72.0% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 54.0 | 4.98e-01 | 100.0% | 71.1% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 57.0 | 5.22e-01 | 100.0% | 74.5% |
| 4bemJ00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.64 | 54.0 | 4.75e-01 | 92.6% | 64.6% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 55.0 | 4.27e-01 | 94.2% | 79.0% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 57.0 | 5.24e-01 | 99.2% | 84.4% |
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.64 | 41.0 | 4.32e-01 | 95.9% | 73.3% |
| 5iduC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 52.0 | 4.75e-01 | 97.5% | 66.7% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.63 | 56.0 | 5.29e-01 | 99.2% | 91.8% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 52.0 | 4.47e-01 | 88.4% | 73.3% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.63 | 46.0 | 4.91e-01 | 76.0% | 98.1% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 49.0 | 4.65e-01 | 84.3% | 78.2% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.62 | 43.0 | 4.24e-01 | 71.9% | 78.2% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.62 | 51.0 | 4.96e-01 | 89.3% | 94.7% |
| 4bg5B00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.61 | 53.0 | 4.55e-01 | 95.9% | 62.3% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 43.0 | 4.29e-01 | 71.1% | 73.0% |
| 1o3uA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.60 | 48.0 | 4.84e-01 | 99.2% | 85.8% |
| 1s05A00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.60 | 50.0 | 4.88e-01 | 93.4% | 83.7% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.60 | 45.0 | 4.04e-01 | 79.3% | 90.5% |
| 6i9kA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 50.0 | 3.79e-01 | 94.2% | 92.6% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.59 | 51.0 | 4.47e-01 | 98.3% | 67.7% |
| 4fz4A00 | 1.20.140.130 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.59 | 51.0 | 4.72e-01 | 95.0% | 91.6% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.58 | 48.0 | 4.48e-01 | 91.7% | 89.2% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.58 | 48.0 | 4.19e-01 | 90.1% | 81.7% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.58 | 47.0 | 4.41e-01 | 98.3% | 69.9% |
| 2q00B00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.58 | 49.0 | 4.93e-01 | 95.0% | 90.2% |
| 1jalA03 | 1.10.150.300 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain | 0.58 | 36.0 | 4.18e-01 | 87.6% | 91.4% |
| 6fakA02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.58 | 38.0 | 4.49e-01 | 87.6% | 100.0% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 40.0 | 3.95e-01 | 70.2% | 70.6% |
| 1gzmA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 51.0 | 3.79e-01 | 100.0% | 86.6% |
| 5j1gA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 45.0 | 3.65e-01 | 85.1% | 70.2% |
| 4cbeA00 | 1.20.120.1640 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.56 | 50.0 | 4.17e-01 | 99.2% | 81.8% |
| 2fsfB04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.55 | 45.0 | 3.80e-01 | 90.9% | 88.2% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.54 | 47.0 | 3.97e-01 | 98.3% | 66.7% |
| 4cgkA01 | 6.10.250.3150 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.54 | 45.0 | 3.75e-01 | 90.9% | 93.9% |
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.53 | 40.0 | 3.63e-01 | 80.2% | 90.2% |
| 2ks9A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 46.0 | 3.40e-01 | 100.0% | 38.6% |
| 4zqeA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.51 | 34.0 | 3.85e-01 | 86.8% | 86.5% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 42.0 | 4.10e-01 | 94.2% | 80.1% |
ECOD (57)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5045176 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.79 | 60.0 | 6.43e-01 | 92.6% | 92.2% |
| 3612331 | 1189.1.1.1 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › Trypan_glycop | 0.78 | 69.0 | 4.83e-01 | 94.2% | 87.0% |
| 3862608 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.73 | 59.0 | 6.18e-01 | 95.9% | 94.5% |
| 3617266 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.73 | 62.0 | 6.26e-01 | 94.2% | 91.7% |
| 3839810 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.72 | 63.0 | 6.03e-01 | 94.2% | 82.1% |
| 3503176 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.72 | 61.0 | 5.62e-01 | 90.1% | 76.7% |
| 3616490 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.72 | 50.0 | 4.64e-01 | 71.1% | 64.0% |
| 3467833 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.71 | 64.0 | 5.26e-01 | 99.2% | 78.6% |
| 3838012 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.71 | 62.0 | 6.19e-01 | 94.2% | 91.2% |
| 1389270 | 3711.1.1.3 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › Metal_resist | 0.71 | 60.0 | 5.75e-01 | 92.6% | 83.1% |
| 3615123 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.70 | 61.0 | 5.30e-01 | 93.4% | 86.1% |
| 5051636 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.70 | 50.0 | 4.81e-01 | 96.7% | 65.2% |
| 3273178 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.70 | 50.0 | 4.19e-01 | 73.6% | 79.5% |
| 3658062 | 3755.4.1.17 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N | 0.69 | 53.0 | 5.11e-01 | 97.5% | 71.9% |
| 3831865 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.69 | 54.0 | 5.35e-01 | 97.5% | 77.7% |
| 3213527 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.69 | 56.0 | 4.26e-01 | 87.6% | 79.6% |
| 3306934 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.68 | 57.0 | 6.00e-01 | 95.9% | 98.2% |
| 3303028 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.68 | 56.0 | 5.19e-01 | 96.7% | 69.0% |
| 3239921 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.68 | 61.0 | 5.53e-01 | 99.2% | 75.2% |
| 3720652 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.68 | 58.0 | 4.60e-01 | 94.2% | 80.0% |
| 3453826 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.67 | 57.0 | 5.85e-01 | 96.7% | 95.7% |
| 3969922 | 633.6.1.4 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_2 | 0.67 | 55.0 | 5.11e-01 | 91.7% | 70.7% |
| 3621079 | 4177.2.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain | 0.67 | 60.0 | 4.71e-01 | 99.2% | 77.3% |
| 3819361 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.66 | 56.0 | 5.26e-01 | 92.6% | 78.0% |
| 3472905 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.66 | 57.0 | 4.90e-01 | 99.2% | 59.5% |
| 3403588 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.66 | 56.0 | 4.43e-01 | 94.2% | 66.5% |
| 3297061 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.65 | 54.0 | 5.55e-01 | 100.0% | 94.8% |
| 3175356 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 57.0 | 5.11e-01 | 99.2% | 89.1% |
| 3398787 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.65 | 56.0 | 5.17e-01 | 96.7% | 76.9% |
| 1481961 | 633.6.1.1 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 | 0.65 | 52.0 | 4.74e-01 | 92.6% | 65.4% |
| 5033597 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.65 | 57.0 | 5.30e-01 | 98.3% | 85.2% |
| 3599199 | 601.30.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 | 0.64 | 57.0 | 5.26e-01 | 98.3% | 85.2% |
| 3228799 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.64 | 56.0 | 4.74e-01 | 95.0% | 89.7% |
| 4797518 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.64 | 56.0 | 5.11e-01 | 98.3% | 80.5% |
| 5074143 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.64 | 56.0 | 5.16e-01 | 98.3% | 82.5% |
| 3450792 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.63 | 54.0 | 5.34e-01 | 96.7% | 88.0% |
| 5047828 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.63 | 56.0 | 5.10e-01 | 99.2% | 81.8% |
| 3409850 | 192.29.1.24 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM237 | 0.63 | 56.0 | 5.00e-01 | 98.3% | 73.7% |
| 4956617 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.63 | 56.0 | 5.14e-01 | 99.2% | 84.4% |
| 3428029 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.63 | 49.0 | 5.36e-01 | 86.0% | 100.0% |
| 3295653 | 4268.2.1.0 ↗ | alpha duplicates or obligate multimers › EspA/CesA-like › EspA chaperone CesA › EspA chaperone CesA | 0.63 | 54.0 | 5.42e-01 | 99.2% | 92.5% |
| 3516779 | 601.15.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) | 0.63 | 56.0 | 4.71e-01 | 100.0% | 79.5% |
| 4947163 | 601.30.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › MMR_HSR1 | 0.63 | 56.0 | 5.15e-01 | 99.2% | 84.4% |
| 3465325 | 3017.1.1.0 ↗ | alpha bundles › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain | 0.63 | 53.0 | 4.92e-01 | 90.9% | 88.7% |
| 3437020 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.62 | 55.0 | 5.08e-01 | 97.5% | 83.9% |
| 3655645 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 55.0 | 5.11e-01 | 97.5% | 91.0% |
| 3251434 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.62 | 49.0 | 4.29e-01 | 83.5% | 96.7% |
| 5042223 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.62 | 53.0 | 5.06e-01 | 97.5% | 80.7% |
| 4360987 | 601.4.1.34 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › SHR3_chaperone | 0.62 | 56.0 | 4.93e-01 | 100.0% | 72.0% |
| 3220378 | 5001.1.1.16 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srt | 0.61 | 48.0 | 3.55e-01 | 85.1% | 32.8% |
| 4991538 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.60 | 53.0 | 4.64e-01 | 95.9% | 67.6% |
| 5009551 | 601.7.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PaREP1 | 0.56 | 47.0 | 4.74e-01 | 99.2% | 88.8% |
| 3306059 | 3755.4.1.46 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › NET2A | 0.55 | 51.0 | 4.00e-01 | 98.3% | 67.7% |
| 3218999 | 5001.1.1.16 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srt | 0.54 | 48.0 | 3.62e-01 | 100.0% | 61.0% |
| 4936312 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.53 | 43.0 | 4.48e-01 | 93.4% | 94.5% |
| 3245048 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 44.0 | 4.26e-01 | 94.2% | 78.6% |
| 3760601 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.52 | 45.0 | 3.46e-01 | 100.0% | 64.5% |
D2
medium
residues 149-292
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3u4qA02 | 1.10.274.50 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › | 0.59 | 27.0 | 2.69e-01 | 70.8% | 40.0% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 39.0 | 4.55e-01 | 75.0% | 94.2% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.57 | 38.0 | 4.30e-01 | 73.6% | 90.7% |
| 3aqbA00 | 1.20.120.1450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.57 | 33.0 | 3.38e-01 | 76.4% | 57.8% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 31.0 | 3.09e-01 | 72.2% | 48.1% |
| 4wk5A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.56 | 38.0 | 3.17e-01 | 81.2% | 39.5% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 35.0 | 3.60e-01 | 75.0% | 63.6% |
| 6tejB01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.55 | 46.0 | 3.69e-01 | 91.0% | 84.8% |
| 1hciA04 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 38.0 | 4.17e-01 | 71.5% | 87.7% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.54 | 37.0 | 3.85e-01 | 70.8% | 74.1% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 38.0 | 3.97e-01 | 70.8% | 78.5% |
| 3cwzB01 | 1.20.58.900 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain | 0.54 | 39.0 | 3.91e-01 | 73.6% | 89.0% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.54 | 34.0 | 3.71e-01 | 79.9% | 74.4% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.51 | 35.0 | 3.90e-01 | 72.2% | 90.9% |
| 5z7qA00 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.51 | 37.0 | 3.50e-01 | 75.7% | 68.8% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5050120 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.68 | 49.0 | 4.57e-01 | 77.8% | 60.3% |
| 4939434 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.65 | 49.0 | 4.60e-01 | 77.8% | 64.7% |
| 3613359 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.65 | 51.0 | 4.33e-01 | 82.6% | 77.0% |
| 4843090 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.65 | 48.0 | 5.27e-01 | 75.7% | 100.0% |
| 3331616 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.65 | 50.0 | 4.24e-01 | 81.2% | 75.8% |
| 3656485 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.65 | 48.0 | 4.12e-01 | 76.4% | 51.1% |
| 3883435 | 5073.1.3.2 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Potassium-transporting ATPase subunit KdpB transmembrane domain › Cation_ATPase_C | 0.64 | 47.0 | 3.92e-01 | 81.9% | 43.1% |
| 5014274 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.64 | 45.0 | 4.01e-01 | 72.9% | 51.5% |
| 4961980 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.64 | 47.0 | 3.90e-01 | 76.4% | 46.9% |
| 4001786 | 1203.1.2.1 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 | 0.63 | 50.0 | 4.40e-01 | 84.0% | 64.1% |
| 3365228 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.61 | 46.0 | 3.64e-01 | 77.8% | 61.3% |
| 4941727 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.61 | 46.0 | 4.26e-01 | 80.6% | 62.0% |
| 3225203 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.60 | 45.0 | 3.94e-01 | 77.8% | 80.0% |
| 3740106 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 38.0 | 4.20e-01 | 71.5% | 82.6% |
| 3969942 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.56 | 37.0 | 4.11e-01 | 73.6% | 83.5% |
| 5003846 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.56 | 41.0 | 3.18e-01 | 75.7% | 55.7% |
| 3741903 | 1025.1.1.6 ↗ | alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain › MARCHF6_C | 0.55 | 39.0 | 3.74e-01 | 73.6% | 62.9% |
| 3650596 | 603.1.1.61 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Mito_carr | 0.55 | 38.0 | 4.30e-01 | 70.8% | 94.5% |
| 162404 | 603.1.1.6 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 | 0.54 | 38.0 | 3.97e-01 | 70.8% | 78.5% |
| 5052059 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 42.0 | 3.74e-01 | 82.6% | 81.4% |
| 3650037 | 604.1.1.127 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › EMC4 | 0.53 | 41.0 | 4.34e-01 | 86.8% | 91.2% |
| 1760269 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.52 | 36.0 | 3.94e-01 | 72.2% | 88.8% |
| 3396744 | 603.1.1.6 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 | 0.52 | 35.0 | 3.21e-01 | 72.9% | 49.7% |
| 3883670 | 604.1.1.7 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 | 0.52 | 36.0 | 3.96e-01 | 73.6% | 86.7% |
| 4027949 | 604.3.1.11 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF155 | 0.52 | 37.0 | 3.89e-01 | 73.6% | 84.6% |
| 4647118 | 5086.1.1.119 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › RRG1_C | 0.52 | 36.0 | 3.15e-01 | 70.8% | 61.8% |
| 3594516 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 37.0 | 3.42e-01 | 73.6% | 89.2% |
| 3591388 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.51 | 36.0 | 3.68e-01 | 70.8% | 86.7% |
| 3596737 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.50 | 35.0 | 3.70e-01 | 73.6% | 79.2% |