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MN270279.1__QGJ86725.1__X__00104
Bact-VirMN270279.1__QGJ86725.1__X__00104
Identity
- Accession:
- MN270279 ↗
- Kingdom:
- phage
Quality
93.4
mean pLDDT
Taxonomy
TaxID: 2664409
Cluster
View cluster (12 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-36_153-219
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01872.23 best | RibD_C | 32.0 | 1.50e-07 | 63.1% | 27.4% |
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2b3zA02 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.88 | 82.0 | 6.13e-01 | 97.1% | 96.0% |
| 2aznA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.88 | 82.0 | 6.19e-01 | 98.1% | 99.5% |
| 1cz3B00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.87 | 81.0 | 6.74e-01 | 98.1% | 99.4% |
| 2p4gA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.87 | 81.0 | 5.93e-01 | 98.1% | 93.1% |
| 4xt6A00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.87 | 80.0 | 5.94e-01 | 97.1% | 90.3% |
| 3zpgA02 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.86 | 79.0 | 6.01e-01 | 97.1% | 95.8% |
| 3ky8A01 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.85 | 76.0 | 6.21e-01 | 93.2% | 100.0% |
| 2g6vA02 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.85 | 79.0 | 5.92e-01 | 97.1% | 95.9% |
| 3kgyA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.85 | 78.0 | 5.92e-01 | 97.1% | 98.6% |
| 3jtwA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.83 | 76.0 | 6.19e-01 | 96.1% | 100.0% |
| 2hxvA02 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.83 | 75.0 | 5.85e-01 | 95.1% | 100.0% |
| 2gd9A01 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.82 | 72.0 | 6.00e-01 | 92.2% | 100.0% |
| 6pf8A01 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.79 | 72.0 | 5.93e-01 | 97.1% | 100.0% |
| 1j3jB00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.79 | 73.0 | 5.63e-01 | 99.0% | 99.5% |
| 2xw7A00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.79 | 72.0 | 5.93e-01 | 97.1% | 98.9% |
| 3k2hA01 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.78 | 72.0 | 5.82e-01 | 99.0% | 97.9% |
| 2w9hA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.78 | 69.0 | 5.92e-01 | 94.2% | 100.0% |
| 3nzbX00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.78 | 71.0 | 5.56e-01 | 98.1% | 99.0% |
| 1dhiA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.78 | 69.0 | 5.87e-01 | 94.2% | 100.0% |
| 5eccA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.78 | 70.0 | 5.95e-01 | 95.1% | 100.0% |
| 4ha7B00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.78 | 72.0 | 5.60e-01 | 99.0% | 90.7% |
| 4eckA01 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.77 | 70.0 | 5.69e-01 | 96.1% | 100.0% |
| 1ao8A00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.77 | 68.0 | 5.74e-01 | 94.2% | 100.0% |
| 1bozA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.77 | 70.0 | 5.66e-01 | 98.1% | 100.0% |
| 1aoeA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.76 | 68.0 | 5.47e-01 | 97.1% | 99.5% |
| 1juvA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.75 | 65.0 | 5.21e-01 | 92.2% | 100.0% |
| 3ix9A00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.75 | 68.0 | 5.76e-01 | 99.0% | 100.0% |
| 3vcoA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.75 | 67.0 | 5.49e-01 | 97.1% | 100.0% |
| 2h2qB01 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.70 | 65.0 | 5.06e-01 | 100.0% | 92.0% |
| 2ip2A02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.63 | 48.0 | 3.63e-01 | 80.6% | 76.4% |
| 6em3x01 | 3.40.50.10480 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Brix domain | 0.60 | 44.0 | 3.61e-01 | 99.0% | 42.7% |
| 6nifA01 | 3.30.900.10 | Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain | 0.58 | 44.0 | 3.61e-01 | 81.6% | 92.6% |
| 3g7uA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.55 | 43.0 | 3.62e-01 | 100.0% | 48.6% |
| 3c3pA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.54 | 41.0 | 3.31e-01 | 80.6% | 82.3% |
| 4qdjA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.53 | 41.0 | 3.32e-01 | 83.5% | 95.2% |
| 4atnA03 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.53 | 42.0 | 3.54e-01 | 99.0% | 48.9% |
| 4lubB01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.53 | 45.0 | 4.60e-01 | 95.1% | 96.0% |
| 4j2gA00 | 3.30.900.10 | Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain | 0.53 | 40.0 | 3.26e-01 | 80.6% | 95.0% |
| 5ewqC00 | 3.90.1300.10 | Alpha Beta › Alpha-Beta Complex › Amidase signature (AS) enzymes › Amidase signature (AS) domain | 0.53 | 47.0 | 3.03e-01 | 100.0% | 35.5% |
| 5tvfD00 | 3.60.90.10 | Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase | 0.53 | 42.0 | 3.12e-01 | 100.0% | 33.0% |
| 3fpfA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.51 | 41.0 | 3.12e-01 | 88.3% | 84.5% |
| 2fiaB00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.51 | 40.0 | 3.51e-01 | 85.4% | 84.9% |
| 3g88A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.51 | 38.0 | 2.94e-01 | 79.6% | 71.5% |
| 3ed4C01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.50 | 45.0 | 3.08e-01 | 100.0% | 84.1% |
ECOD (72)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4949256 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.92 | 85.0 | 6.39e-01 | 97.1% | 100.0% |
| 5030442 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.88 | 80.0 | 6.53e-01 | 94.2% | 100.0% |
| 4123104 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.88 | 81.0 | 6.70e-01 | 96.1% | 100.0% |
| 5015705 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.88 | 80.0 | 5.99e-01 | 96.1% | 94.8% |
| 5082494 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.88 | 82.0 | 6.22e-01 | 99.0% | 100.0% |
| 4262258 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.88 | 82.0 | 6.13e-01 | 98.1% | 96.4% |
| 5056796 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.88 | 74.0 | 5.73e-01 | 87.4% | 100.0% |
| 163852 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.87 | 81.0 | 5.93e-01 | 98.1% | 93.1% |
| 4968801 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.87 | 80.0 | 6.00e-01 | 97.1% | 91.7% |
| 5001085 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.87 | 83.0 | 6.12e-01 | 100.0% | 94.5% |
| 5048917 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.87 | 79.0 | 5.99e-01 | 96.1% | 98.2% |
| 3953555 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.87 | 80.0 | 6.35e-01 | 97.1% | 99.5% |
| 1764169 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.86 | 80.0 | 5.84e-01 | 97.1% | 89.0% |
| 5057520 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.86 | 79.0 | 5.96e-01 | 96.1% | 94.1% |
| 4238819 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.86 | 81.0 | 6.11e-01 | 99.0% | 99.5% |
| 4663296 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.86 | 81.0 | 6.11e-01 | 99.0% | 100.0% |
| 5050939 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.86 | 81.0 | 6.02e-01 | 100.0% | 98.3% |
| 2389059 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.86 | 80.0 | 5.93e-01 | 99.0% | 94.6% |
| 5029141 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.86 | 81.0 | 6.63e-01 | 100.0% | 98.9% |
| 235716 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.86 | 78.0 | 6.01e-01 | 96.1% | 100.0% |
| 137569 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.85 | 78.0 | 6.35e-01 | 96.1% | 100.0% |
| 163314 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.85 | 79.0 | 5.95e-01 | 97.1% | 97.3% |
| 4577003 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.85 | 79.0 | 6.07e-01 | 99.0% | 100.0% |
| 5058063 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.85 | 79.0 | 6.42e-01 | 97.1% | 100.0% |
| 3282327 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.85 | 78.0 | 6.11e-01 | 96.1% | 100.0% |
| 4033392 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.85 | 78.0 | 6.00e-01 | 97.1% | 99.5% |
| 4959428 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.85 | 79.0 | 6.00e-01 | 100.0% | 98.2% |
| 4946280 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.85 | 77.0 | 5.88e-01 | 97.1% | 100.0% |
| 3974710 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.85 | 79.0 | 6.41e-01 | 98.1% | 100.0% |
| 3590464 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.84 | 77.0 | 6.30e-01 | 96.1% | 100.0% |
| 3282759 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.84 | 76.0 | 6.15e-01 | 96.1% | 100.0% |
| 5073892 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.84 | 78.0 | 6.22e-01 | 99.0% | 100.0% |
| 3284365 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.83 | 76.0 | 6.04e-01 | 97.1% | 100.0% |
| 10273 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.83 | 75.0 | 5.85e-01 | 95.1% | 100.0% |
| 3182252 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.82 | 75.0 | 5.43e-01 | 98.1% | 90.0% |
| 3277763 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.82 | 75.0 | 6.00e-01 | 96.1% | 100.0% |
| 160146 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.82 | 74.0 | 6.07e-01 | 96.1% | 97.2% |
| 4392834 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.81 | 76.0 | 5.74e-01 | 100.0% | 99.6% |
| 5063695 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.81 | 74.0 | 5.89e-01 | 96.1% | 98.9% |
| 3593841 | 7501.1.1.0 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases | 0.81 | 74.0 | 5.64e-01 | 97.1% | 95.0% |
| 3289265 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.81 | 72.0 | 5.83e-01 | 94.2% | 100.0% |
| 3371194 | 7501.1.1.0 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases | 0.80 | 73.0 | 5.67e-01 | 98.1% | 99.1% |
| 3010946 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.80 | 72.0 | 5.87e-01 | 95.1% | 100.0% |
| 3279668 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.80 | 72.0 | 5.80e-01 | 96.1% | 100.0% |
| 3278543 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.80 | 72.0 | 5.75e-01 | 96.1% | 100.0% |
| 169540 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.79 | 73.0 | 6.13e-01 | 98.1% | 98.8% |
| 3289701 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.79 | 73.0 | 5.60e-01 | 98.1% | 100.0% |
| 4652224 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.79 | 72.0 | 6.03e-01 | 96.1% | 100.0% |
| 4115051 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.79 | 74.0 | 5.50e-01 | 100.0% | 98.8% |
| 4624802 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.79 | 71.0 | 5.96e-01 | 95.1% | 100.0% |
| 3430689 | 7501.1.1.0 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases | 0.79 | 71.0 | 5.56e-01 | 96.1% | 100.0% |
| 2503171 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.79 | 73.0 | 6.00e-01 | 100.0% | 100.0% |
| 185430 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.79 | 72.0 | 5.81e-01 | 98.1% | 97.8% |
| 4279950 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.78 | 72.0 | 5.99e-01 | 97.1% | 100.0% |
| 10268 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.78 | 71.0 | 5.54e-01 | 98.1% | 99.0% |
| 3286316 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.77 | 71.0 | 5.76e-01 | 99.0% | 100.0% |
| 3665992 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.77 | 67.0 | 5.31e-01 | 93.2% | 100.0% |
| 4021830 | 7501.1.1.0 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases | 0.77 | 70.0 | 5.34e-01 | 98.1% | 100.0% |
| 2831687 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.76 | 69.0 | 5.74e-01 | 98.1% | 93.6% |
| 137968 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.75 | 68.0 | 5.76e-01 | 99.0% | 100.0% |
| 3056343 | 7501.1.1.1 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 | 0.75 | 67.0 | 5.22e-01 | 97.1% | 94.8% |
| 162261 | 2003.1.5.3 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 | 0.63 | 48.0 | 3.62e-01 | 80.6% | 77.5% |
| 3401014 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.61 | 44.0 | 3.49e-01 | 97.1% | 36.7% |
| 4028342 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.60 | 46.0 | 3.26e-01 | 99.0% | 27.9% |
| 4530628 | 859.1.1.4 ↗ | a+b two layers › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › ATG13 | 0.55 | 41.0 | 3.11e-01 | 79.6% | 95.6% |
| 4967537 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.55 | 43.0 | 3.81e-01 | 98.1% | 57.3% |
| 1503818 | 2003.1.5.27 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NAS | 0.54 | 43.0 | 3.24e-01 | 88.3% | 74.3% |
| 4954717 | 2003.1.5.27 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NAS | 0.53 | 38.0 | 3.64e-01 | 97.1% | 63.3% |
| 4334524 | 4143.1.1.5 ↗ | a+b two layers › THUMP domain-like › THUMP domain-like › THUMP domain-like › RLMM_N | 0.53 | 34.0 | 3.52e-01 | 97.1% | 68.4% |
| 4157476 | 2003.1.5.25 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GidB | 0.52 | 41.0 | 3.15e-01 | 84.5% | 75.4% |
| 4448813 | 2003.1.5.25 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GidB | 0.51 | 40.0 | 3.12e-01 | 84.5% | 77.4% |
| 3201008 | 2003.1.5.368 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT, WBS_methylT, Methyltransf_25 | 0.51 | 41.0 | 3.03e-01 | 87.4% | 72.5% |
D2
medium
residues 37-152
Domain cluster:
representative
CATH (53)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2b3zA02 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.78 | 68.0 | 5.29e-01 | 100.0% | 46.7% |
| 2aznA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.78 | 69.0 | 5.43e-01 | 100.0% | 48.9% |
| 4cvhA01 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.72 | 50.0 | 3.99e-01 | 72.4% | 69.1% |
| 1ll0B00 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.71 | 52.0 | 3.97e-01 | 76.7% | 80.1% |
| 4kt7A00 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.70 | 49.0 | 3.95e-01 | 73.3% | 68.3% |
| 2p4gA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.70 | 66.0 | 4.99e-01 | 100.0% | 49.2% |
| 2d13A01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.66 | 48.0 | 4.85e-01 | 75.9% | 98.2% |
| 4jd0A00 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.66 | 45.0 | 3.59e-01 | 71.6% | 69.4% |
| 5ybwA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.64 | 51.0 | 5.48e-01 | 93.1% | 100.0% |
| 5cvcA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.64 | 50.0 | 5.46e-01 | 93.1% | 100.0% |
| 1wkvA03 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.63 | 51.0 | 5.47e-01 | 95.7% | 100.0% |
| 2wj6A01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.63 | 54.0 | 4.48e-01 | 94.8% | 52.9% |
| 1tdjA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.62 | 47.0 | 5.19e-01 | 94.0% | 100.0% |
| 5b1hA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.62 | 51.0 | 5.44e-01 | 94.8% | 100.0% |
| 5c3uA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.62 | 48.0 | 5.23e-01 | 93.1% | 100.0% |
| 2iojA00 | 3.40.1390.20 | Alpha Beta › 3-Layer(aba) Sandwich › Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 › HprK N-terminal domain-like | 0.62 | 48.0 | 4.78e-01 | 100.0% | 79.2% |
| 1p5jA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.61 | 48.0 | 5.22e-01 | 93.1% | 100.0% |
| 5z5cA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.60 | 50.0 | 5.22e-01 | 94.8% | 96.3% |
| 5d84A02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.60 | 51.0 | 5.23e-01 | 94.0% | 95.5% |
| 1mjhB00 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.59 | 41.0 | 3.91e-01 | 72.4% | 96.5% |
| 3m1lA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.59 | 50.0 | 4.13e-01 | 92.2% | 88.3% |
| 3okpA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.59 | 50.0 | 4.26e-01 | 93.1% | 97.4% |
| 4igiA00 | 3.40.50.410 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain | 0.58 | 50.0 | 4.19e-01 | 93.1% | 90.4% |
| 3r0xA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.58 | 52.0 | 5.13e-01 | 96.6% | 98.4% |
| 4d9gA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.57 | 50.0 | 4.99e-01 | 94.8% | 96.6% |
| 1kjnA00 | 3.40.50.10160 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › MTH777-like | 0.57 | 50.0 | 4.56e-01 | 94.8% | 98.0% |
| 5i7wA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.57 | 50.0 | 5.05e-01 | 94.8% | 96.5% |
| 6xo2A01 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.57 | 47.0 | 4.98e-01 | 89.7% | 100.0% |
| 4lwoE01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.56 | 49.0 | 4.40e-01 | 94.8% | 93.1% |
| 4wfqA00 | 3.40.50.410 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain | 0.56 | 46.0 | 3.98e-01 | 92.2% | 95.8% |
| 1j6uA03 | 3.90.190.20 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain | 0.55 | 43.0 | 4.20e-01 | 100.0% | 74.2% |
| 1pjqA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.55 | 40.0 | 4.14e-01 | 76.7% | 85.7% |
| 3cfyA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 46.0 | 4.49e-01 | 93.1% | 90.0% |
| 1knxA01 | 3.40.1390.20 | Alpha Beta › 3-Layer(aba) Sandwich › Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 › HprK N-terminal domain-like | 0.55 | 44.0 | 4.28e-01 | 95.7% | 76.7% |
| 3n75A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 46.0 | 4.46e-01 | 93.1% | 94.6% |
| 1peqA02 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.54 | 48.0 | 3.16e-01 | 96.6% | 37.9% |
| 3lk7A03 | 3.90.190.20 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain | 0.53 | 46.0 | 4.43e-01 | 100.0% | 82.8% |
| 4ggjA00 | 3.30.870.10 | Alpha Beta › 2-Layer Sandwich › Endonuclease; Chain A › Endonuclease Chain A | 0.53 | 43.0 | 3.83e-01 | 86.2% | 95.2% |
| 4rhiA00 | 3.40.800.10 | Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain | 0.53 | 47.0 | 3.50e-01 | 99.1% | 47.8% |
| 5temA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 45.0 | 4.07e-01 | 92.2% | 89.9% |
| 4nnaA01 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.53 | 44.0 | 3.25e-01 | 93.1% | 74.4% |
| 5gvrA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 40.0 | 3.23e-01 | 81.0% | 70.1% |
| 1u1jA01 | 3.20.20.210 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › | 0.53 | 47.0 | 3.28e-01 | 100.0% | 97.3% |
| 4gx0B04 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 41.0 | 3.92e-01 | 81.0% | 88.5% |
| 6n2nC03 | 3.40.50.920 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 42.0 | 4.35e-01 | 87.1% | 100.0% |
| 2oczA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.52 | 45.0 | 3.71e-01 | 95.7% | 78.9% |
| 1xmxA02 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.52 | 44.0 | 4.11e-01 | 94.0% | 75.8% |
| 2fp4A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.51 | 37.0 | 3.68e-01 | 75.9% | 92.7% |
| 2egzC00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.51 | 45.0 | 3.68e-01 | 97.4% | 78.0% |
| 2l3fA00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.51 | 42.0 | 3.80e-01 | 90.5% | 97.5% |
| 1u0tB01 | 3.40.50.10330 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Probable inorganic polyphosphate/atp-NAD kinase; domain 1 | 0.50 | 41.0 | 3.86e-01 | 93.1% | 72.7% |
| 4tjvA00 | 3.50.30.30 | Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › | 0.50 | 44.0 | 3.90e-01 | 95.7% | 66.7% |
| 3ngxA02 | 3.40.50.10860 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 | 0.50 | 33.0 | 3.72e-01 | 73.3% | 91.7% |
ECOD (82)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4949256 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.97 | 94.0 | 7.29e-01 | 100.0% | 55.0% |
| 4980571 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.95 | 92.0 | 7.15e-01 | 100.0% | 53.2% |
| 5082494 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.93 | 90.0 | 6.98e-01 | 100.0% | 52.7% |
| 4959428 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.83 | 71.0 | 5.52e-01 | 100.0% | 45.8% |
| 4992215 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.82 | 70.0 | 5.49e-01 | 100.0% | 47.9% |
| 5056796 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.81 | 71.0 | 5.77e-01 | 100.0% | 53.0% |
| 5001085 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.80 | 72.0 | 5.54e-01 | 100.0% | 46.4% |
| 4262258 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.80 | 69.0 | 5.38e-01 | 100.0% | 46.7% |
| 5048917 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.80 | 70.0 | 5.51e-01 | 100.0% | 48.6% |
| 2389059 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.78 | 73.0 | 5.54e-01 | 100.0% | 47.3% |
| 4816241 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.77 | 67.0 | 5.73e-01 | 100.0% | 60.3% |
| 4663296 | 7501.1.1.2 ↗ | a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C | 0.77 | 69.0 | 5.41e-01 | 100.0% | 49.5% |
| 3723513 | 7516.1.1.0 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases | 0.71 | 52.0 | 3.95e-01 | 75.9% | 89.4% |
| 5030628 | 7516.1.1.0 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases | 0.71 | 50.0 | 4.31e-01 | 73.3% | 99.5% |
| 3187646 | 7516.1.1.0 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases | 0.71 | 51.0 | 3.62e-01 | 74.1% | 83.4% |
| 3637314 | 7516.1.1.6 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_8 | 0.70 | 51.0 | 3.69e-01 | 75.9% | 76.1% |
| 5058184 | 7516.1.1.10 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › CofC | 0.68 | 48.0 | 3.73e-01 | 73.3% | 58.8% |
| 4979988 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.66 | 46.0 | 4.58e-01 | 71.6% | 90.0% |
| 4639154 | 7516.1.1.5 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › IspD | 0.64 | 45.0 | 3.76e-01 | 72.4% | 93.5% |
| 2482863 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.63 | 50.0 | 4.47e-01 | 93.1% | 59.4% |
| 4184010 | 2003.1.1.22 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GFO_IDH_MocA | 0.63 | 44.0 | 4.07e-01 | 73.3% | 82.0% |
| 3652829 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.63 | 44.0 | 4.15e-01 | 72.4% | 97.1% |
| 3510085 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.62 | 50.0 | 4.51e-01 | 93.1% | 61.9% |
| None | — | 0.62 | 43.0 | 2.67e-01 | 70.7% | 17.3% | |
| 5077475 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.62 | 49.0 | 4.35e-01 | 93.1% | 58.8% |
| 3438965 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.62 | 43.0 | 4.62e-01 | 72.4% | 100.0% |
| 3886006 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.62 | 49.0 | 4.54e-01 | 92.2% | 65.3% |
| 4436110 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.62 | 52.0 | 4.75e-01 | 94.8% | 69.3% |
| 3654551 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.62 | 54.0 | 4.56e-01 | 94.8% | 58.4% |
| 4181298 | 601.23.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III | 0.62 | 45.0 | 3.04e-01 | 75.9% | 30.2% |
| 5054417 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.62 | 52.0 | 5.10e-01 | 90.5% | 92.8% |
| 5010456 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.62 | 50.0 | 4.66e-01 | 94.8% | 69.0% |
| 3450582 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.62 | 44.0 | 4.30e-01 | 75.0% | 93.1% |
| 2483672 | 2003.4.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0.61 | 52.0 | 4.94e-01 | 94.8% | 79.1% |
| 2483890 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.61 | 49.0 | 4.62e-01 | 94.8% | 71.7% |
| 4034607 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.61 | 51.0 | 4.57e-01 | 90.5% | 89.4% |
| 2484608 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.61 | 51.0 | 4.53e-01 | 90.5% | 87.8% |
| 4966826 | 2008.1.1.16 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat | 0.60 | 44.0 | 4.49e-01 | 92.2% | 76.5% |
| 3588585 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.60 | 51.0 | 4.64e-01 | 93.1% | 68.4% |
| 3467957 | 2007.1.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like | 0.60 | 52.0 | 4.69e-01 | 93.1% | 85.2% |
| 4947473 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.60 | 51.0 | 4.66e-01 | 90.5% | 91.3% |
| 4943076 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.60 | 50.0 | 4.69e-01 | 90.5% | 89.7% |
| 4853121 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.60 | 52.0 | 4.97e-01 | 94.8% | 81.8% |
| 3229670 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.60 | 50.0 | 4.64e-01 | 91.4% | 91.3% |
| 3591096 | 2003.4.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0.60 | 50.0 | 4.55e-01 | 90.5% | 87.1% |
| 3781671 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.59 | 50.0 | 4.66e-01 | 92.2% | 73.1% |
| 3287704 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.59 | 50.0 | 4.56e-01 | 90.5% | 88.0% |
| 2483388 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.59 | 50.0 | 4.66e-01 | 90.5% | 95.1% |
| 5075326 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.59 | 50.0 | 4.56e-01 | 90.5% | 86.0% |
| 4545598 | 2484.1.1.48 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II | 0.59 | 42.0 | 3.80e-01 | 75.9% | 82.9% |
| 3284891 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.59 | 49.0 | 4.53e-01 | 90.5% | 90.0% |
| 3887384 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.59 | 49.0 | 4.34e-01 | 90.5% | 78.8% |
| 3289549 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.59 | 51.0 | 4.55e-01 | 94.0% | 67.5% |
| 4979139 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.59 | 49.0 | 4.51e-01 | 90.5% | 86.7% |
| 3254521 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.59 | 49.0 | 4.76e-01 | 90.5% | 92.3% |
| 4957244 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.59 | 40.0 | 4.23e-01 | 89.7% | 78.1% |
| 3341460 | 2004.1.1.56 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC | 0.59 | 41.0 | 3.36e-01 | 77.6% | 40.5% |
| 4962596 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.58 | 48.0 | 4.33e-01 | 90.5% | 77.6% |
| 4971798 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.58 | 48.0 | 4.51e-01 | 89.7% | 89.7% |
| 4977399 | 2006.1.6.12 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 | 0.58 | 49.0 | 4.00e-01 | 92.2% | 74.5% |
| 3946439 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.58 | 48.0 | 4.47e-01 | 90.5% | 92.0% |
| 4943406 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.58 | 48.0 | 4.45e-01 | 89.7% | 86.7% |
| None | — | 0.58 | 45.0 | 4.19e-01 | 81.9% | 91.6% | |
| 3717817 | 2003.1.5.11 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PARP_regulatory | 0.58 | 50.0 | 3.69e-01 | 94.0% | 63.3% |
| 3623081 | 7585.1.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Sec1 | 0.58 | 44.0 | 4.24e-01 | 81.0% | 79.3% |
| 4888036 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.58 | 50.0 | 4.58e-01 | 94.8% | 71.4% |
| 3180238 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.58 | 49.0 | 4.78e-01 | 91.4% | 100.0% |
| 5059579 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.57 | 49.0 | 4.45e-01 | 94.0% | 69.4% |
| 3995249 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.57 | 51.0 | 4.44e-01 | 99.1% | 94.4% |
| 4975081 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.57 | 40.0 | 3.64e-01 | 72.4% | 74.2% |
| 5060873 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.57 | 48.0 | 4.08e-01 | 90.5% | 76.2% |
| 5023877 | 2487.1.1.0 ↗ | a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" | 0.56 | 43.0 | 4.25e-01 | 92.2% | 76.0% |
| 5018056 | 2487.1.1.0 ↗ | a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" | 0.56 | 44.0 | 4.11e-01 | 92.2% | 68.6% |
| 4032212 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.56 | 49.0 | 3.60e-01 | 100.0% | 79.1% |
| 4939934 | 2487.1.1.0 ↗ | a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" | 0.55 | 43.0 | 4.13e-01 | 92.2% | 71.9% |
| 5032144 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.55 | 50.0 | 4.15e-01 | 99.1% | 91.0% |
| 4946561 | 2002.1.1.56 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Dus | 0.55 | 48.0 | 3.53e-01 | 95.7% | 62.5% |
| 4342582 | 7570.1.1.1 ↗ | a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C | 0.55 | 49.0 | 4.44e-01 | 100.0% | 75.0% |
| 4602260 | 7570.1.1.1 ↗ | a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C | 0.55 | 49.0 | 4.44e-01 | 100.0% | 75.5% |
| 3603194 | 7595.1.1.1 ↗ | a/b three-layered sandwiches › B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit › B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit › B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit › CdhD | 0.55 | 45.0 | 4.28e-01 | 87.9% | 94.8% |
| 2462401 | 7522.1.1.4 ↗ | a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PFOR_II | 0.54 | 43.0 | 4.33e-01 | 85.3% | 96.6% |
| 4345482 | 7595.1.1.1 ↗ | a/b three-layered sandwiches › B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit › B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit › B12 binding domain in carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit › CdhD | 0.53 | 42.0 | 4.07e-01 | 86.2% | 96.3% |