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MN857473.1__QOC54135.1__X__00020
Bact-VirMN857473.1__QOC54135.1__X__00020
Identity
- Accession:
- MN857473 ↗
- Kingdom:
- phage
Quality
79.8
mean pLDDT
Taxonomy
TaxID: 2759120
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 209-318
Domain cluster:
representative
CATH (36)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.68 | 50.0 | 4.92e-01 | 76.4% | 100.0% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.66 | 48.0 | 5.06e-01 | 74.5% | 95.9% |
| 3rkvA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 44.0 | 3.99e-01 | 83.6% | 51.0% |
| 1gxmB00 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.62 | 53.0 | 3.76e-01 | 91.8% | 71.1% |
| 4lp8A01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 36.0 | 3.74e-01 | 86.4% | 60.6% |
| 1a17A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 52.0 | 4.59e-01 | 100.0% | 62.9% |
| 3na8A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.61 | 41.0 | 2.99e-01 | 71.8% | 25.8% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 48.0 | 4.72e-01 | 84.5% | 100.0% |
| 2e2eA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 41.0 | 3.68e-01 | 84.5% | 49.7% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.61 | 45.0 | 4.82e-01 | 98.2% | 90.3% |
| 4me2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 44.0 | 3.64e-01 | 76.4% | 49.0% |
| 3mk7A00 | 1.20.210.10 | Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain | 0.60 | 48.0 | 3.13e-01 | 85.5% | 86.7% |
| 3beeA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 36.0 | 3.86e-01 | 75.5% | 70.3% |
| 2z0qA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.58 | 50.0 | 4.20e-01 | 95.5% | 91.2% |
| 5gj7A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.58 | 43.0 | 4.16e-01 | 77.3% | 77.6% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.58 | 42.0 | 4.31e-01 | 76.4% | 85.2% |
| 2nnwA02 | 1.10.287.4070 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 46.0 | 4.36e-01 | 93.6% | 72.4% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 40.0 | 4.36e-01 | 73.6% | 96.8% |
| 3cf6E03 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.56 | 44.0 | 4.23e-01 | 85.5% | 96.2% |
| 2ozbB01 | 1.10.287.4070 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 45.0 | 4.23e-01 | 93.6% | 71.0% |
| 3gw4A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 38.0 | 3.22e-01 | 76.4% | 40.6% |
| 1ki1B01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.56 | 44.0 | 3.62e-01 | 83.6% | 92.0% |
| 2dfkC01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.55 | 50.0 | 4.01e-01 | 100.0% | 92.9% |
| 1d5rA01 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.54 | 41.0 | 3.52e-01 | 80.0% | 92.5% |
| 2l6jA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 37.0 | 3.79e-01 | 75.5% | 73.0% |
| 2jexA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.53 | 39.0 | 4.22e-01 | 88.2% | 88.5% |
| 2j9wB00 | 1.20.120.1130 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain | 0.53 | 33.0 | 3.48e-01 | 70.0% | 68.7% |
| 1dtoA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.53 | 39.0 | 4.08e-01 | 87.3% | 83.3% |
| 6orcB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 36.0 | 3.36e-01 | 75.5% | 57.5% |
| 7wj9A01 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.52 | 42.0 | 3.07e-01 | 87.3% | 32.4% |
| 3nf2A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.52 | 44.0 | 3.16e-01 | 93.6% | 76.9% |
| 3aqbA00 | 1.20.120.1450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.51 | 40.0 | 3.80e-01 | 84.5% | 78.5% |
| 1ouvA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 37.0 | 2.79e-01 | 75.5% | 31.3% |
| 6ok0B01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 35.0 | 3.50e-01 | 75.5% | 67.2% |
| 6orkA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.50 | 36.0 | 2.82e-01 | 79.1% | 33.1% |
| 2g7gA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 40.0 | 3.39e-01 | 88.2% | 82.2% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3693314 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.67 | 60.0 | 4.25e-01 | 99.1% | 82.4% |
| 3573846 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.66 | 51.0 | 3.83e-01 | 88.2% | 34.0% |
| 3883327 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 46.0 | 3.92e-01 | 76.4% | 46.9% |
| 5072449 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.63 | 49.0 | 5.40e-01 | 80.9% | 98.9% |
| 4549 | 109.4.1.1802 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, PPP5, TPR_16 | 0.62 | 52.0 | 4.59e-01 | 100.0% | 62.9% |
| 4192699 | 603.5.1.1 ↗ | alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN | 0.61 | 49.0 | 4.69e-01 | 87.3% | 93.8% |
| 3486342 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 46.0 | 3.66e-01 | 84.5% | 40.5% |
| 3648149 | 109.4.1.1292 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3 | 0.60 | 45.0 | 3.28e-01 | 80.0% | 34.8% |
| 4607020 | 192.2.1.3 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Rad50_zn_hook | 0.60 | 41.0 | 3.82e-01 | 97.3% | 57.0% |
| 3804359 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.59 | 42.0 | 3.83e-01 | 80.0% | 55.9% |
| 4197128 | 109.4.1.109 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 | 0.59 | 42.0 | 3.95e-01 | 74.5% | 84.4% |
| 3556139 | 109.4.1.109 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 | 0.58 | 47.0 | 3.64e-01 | 90.9% | 40.4% |
| 4988993 | 5086.1.1.231 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Rad50_zn_hook | 0.58 | 43.0 | 3.86e-01 | 97.3% | 56.7% |
| 3737926 | 133.1.1.0 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) | 0.58 | 51.0 | 4.28e-01 | 94.5% | 93.3% |
| 3804939 | 192.2.1.3 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Rad50_zn_hook | 0.57 | 40.0 | 3.74e-01 | 97.3% | 56.4% |
| None | — | 0.57 | 44.0 | 3.44e-01 | 85.5% | 39.1% | |
| 3438458 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 44.0 | 3.30e-01 | 85.5% | 53.3% |
| 3446135 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.56 | 38.0 | 3.18e-01 | 76.4% | 38.0% |
| 3520908 | 109.4.1.2116 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30807 | 0.55 | 48.0 | 3.18e-01 | 99.1% | 32.0% |
| 3670055 | 109.4.1.109 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 | 0.55 | 37.0 | 3.28e-01 | 83.6% | 45.3% |
| 3934155 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 41.0 | 4.28e-01 | 80.0% | 95.0% |
| 3930124 | 109.25.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN | 0.55 | 47.0 | 4.44e-01 | 92.7% | 96.9% |
| 3459453 | 109.4.1.1257 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 | 0.54 | 40.0 | 4.02e-01 | 78.2% | 89.1% |
| 3967188 | 5051.1.1.2 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease | 0.53 | 47.0 | 3.04e-01 | 93.6% | 87.9% |
| 4018322 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.53 | 44.0 | 4.03e-01 | 89.1% | 97.9% |
| 3722842 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.53 | 46.0 | 3.08e-01 | 100.0% | 79.4% |
| 3839494 | 109.4.1.109 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 | 0.52 | 37.0 | 3.69e-01 | 76.4% | 70.4% |
| 3702813 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 45.0 | 3.19e-01 | 98.2% | 52.1% |
| 3973909 | 109.4.1.109 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 | 0.51 | 43.0 | 3.72e-01 | 92.7% | 73.1% |
| 3597412 | 5076.1.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier | 0.51 | 39.0 | 2.98e-01 | 80.9% | 75.1% |
| 5059126 | 5051.1.1.2 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease | 0.51 | 42.0 | 2.80e-01 | 89.1% | 83.8% |
| 4588403 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.50 | 40.0 | 3.70e-01 | 88.2% | 75.3% |
| None | — | 0.50 | 44.0 | 3.26e-01 | 98.2% | 55.3% | |
| 3440540 | 192.15.1.180 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Sec10_HB, Sec10_N | 0.50 | 43.0 | 4.00e-01 | 91.8% | 74.8% |
D2
high
residues 454-531
Domain cluster:
representative
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2aplA01 | 1.10.8.330 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like | 0.71 | 55.0 | 5.88e-01 | 82.1% | 98.5% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.71 | 54.0 | 4.31e-01 | 82.1% | 54.8% |
| 7s0rB01 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.69 | 51.0 | 5.20e-01 | 82.1% | 81.6% |
| 2rn7A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.67 | 39.0 | 4.18e-01 | 71.8% | 68.2% |
| 3a11B01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.66 | 48.0 | 4.13e-01 | 82.1% | 48.0% |
| 3djbA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.64 | 55.0 | 5.17e-01 | 98.7% | 87.5% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.63 | 48.0 | 4.80e-01 | 83.3% | 89.0% |
| 1t6jA03 | 1.10.274.20 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 | 0.63 | 53.0 | 4.94e-01 | 96.2% | 90.3% |
| 4rocA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.63 | 50.0 | 4.65e-01 | 89.7% | 77.7% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.63 | 49.0 | 4.55e-01 | 85.9% | 77.2% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 54.0 | 4.42e-01 | 98.7% | 77.3% |
| 4z7xB00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.62 | 50.0 | 3.78e-01 | 100.0% | 34.1% |
| 1kq4A00 | 3.30.1360.170 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.62 | 48.0 | 3.54e-01 | 94.9% | 32.0% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.61 | 53.0 | 5.29e-01 | 100.0% | 98.8% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 51.0 | 4.18e-01 | 97.4% | 68.8% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 47.0 | 4.25e-01 | 85.9% | 69.2% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 49.0 | 4.10e-01 | 96.2% | 69.1% |
| 3i2fA02 | 1.10.3020.10 | Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) | 0.60 | 50.0 | 4.74e-01 | 100.0% | 77.9% |
| 2g7sA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 45.0 | 3.41e-01 | 82.1% | 56.8% |
| 3nqxA02 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.59 | 48.0 | 4.00e-01 | 92.3% | 96.6% |
| 3ibyD02 | 1.10.287.1770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 41.0 | 4.01e-01 | 98.7% | 69.0% |
| 4o1gA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.58 | 48.0 | 3.14e-01 | 89.7% | 29.1% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 50.0 | 4.24e-01 | 98.7% | 81.2% |
| 1x42A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.57 | 49.0 | 4.81e-01 | 96.2% | 94.0% |
| 2d4uB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.57 | 43.0 | 3.48e-01 | 82.1% | 47.1% |
| 2py6A01 | 1.20.1270.160 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 46.0 | 4.71e-01 | 97.4% | 95.9% |
| 2f02B00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.56 | 50.0 | 3.34e-01 | 100.0% | 29.6% |
| 4gmqA00 | 1.10.8.840 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ribosome-associated complex head domain | 0.56 | 42.0 | 4.06e-01 | 88.5% | 70.7% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.55 | 43.0 | 3.87e-01 | 85.9% | 65.2% |
| 2nwhA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.55 | 50.0 | 3.30e-01 | 100.0% | 40.7% |
| 3bf5A01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.55 | 46.0 | 3.27e-01 | 92.3% | 47.1% |
| 3ckcA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 41.0 | 3.20e-01 | 82.1% | 61.0% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.54 | 47.0 | 3.76e-01 | 98.7% | 60.9% |
| 2fp1B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.53 | 46.0 | 3.70e-01 | 100.0% | 56.7% |
| 2kilA00 | 3.90.1520.10 | Alpha Beta › Alpha-Beta Complex › H-NOX domain › H-NOX domain | 0.53 | 46.0 | 3.55e-01 | 98.7% | 79.0% |
| 4k7cA01 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.53 | 42.0 | 2.78e-01 | 92.3% | 94.9% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 44.0 | 4.14e-01 | 100.0% | 87.3% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.52 | 40.0 | 3.76e-01 | 79.5% | 81.3% |
| 5gl7A01 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.52 | 43.0 | 3.41e-01 | 91.0% | 87.3% |
| 4jbeB01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.51 | 43.0 | 3.03e-01 | 97.4% | 43.4% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.50 | 41.0 | 2.84e-01 | 97.4% | 82.8% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3283999 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.77 | 58.0 | 5.24e-01 | 80.8% | 78.1% |
| 3943210 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.71 | 52.0 | 3.92e-01 | 78.2% | 50.0% |
| 3115 | 4199.1.1.1 ↗ | alpha arrays › PG0816-like › PG0816-like › PG0816-like › DUF1896 | 0.70 | 55.0 | 4.42e-01 | 83.3% | 46.3% |
| 3287733 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.69 | 59.0 | 6.04e-01 | 97.4% | 100.0% |
| 3958634 | 5067.1.1.4 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL | 0.69 | 52.0 | 3.89e-01 | 82.1% | 39.5% |
| 4026473 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.67 | 53.0 | 4.21e-01 | 85.9% | 65.0% |
| 3686609 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.67 | 58.0 | 5.59e-01 | 97.4% | 100.0% |
| 5001331 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.66 | 56.0 | 5.03e-01 | 97.4% | 82.6% |
| 4029182 | 3871.1.1.0 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST | 0.65 | 51.0 | 4.17e-01 | 85.9% | 65.3% |
| 3954012 | 5073.1.2.0 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain | 0.65 | 52.0 | 3.59e-01 | 84.6% | 79.2% |
| 3608773 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.64 | 54.0 | 4.30e-01 | 93.6% | 78.8% |
| 5070523 | 4044.1.1.0 ↗ | alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins | 0.64 | 50.0 | 4.72e-01 | 85.9% | 69.5% |
| 5023436 | 210.1.1.0 ↗ | a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits | 0.63 | 56.0 | 3.97e-01 | 98.7% | 86.4% |
| 3595205 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.63 | 49.0 | 3.59e-01 | 85.9% | 33.2% |
| 5076381 | 101.1.10.3 ↗ | alpha arrays › HTH › HTH › Cyclin-like › TFIIB | 0.61 | 49.0 | 4.57e-01 | 89.7% | 77.0% |
| 3943353 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.61 | 46.0 | 4.45e-01 | 83.3% | 87.8% |
| 3973240 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.60 | 52.0 | 3.96e-01 | 100.0% | 80.5% |
| 5052614 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.60 | 44.0 | 4.08e-01 | 83.3% | 93.6% |
| 3974204 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.60 | 46.0 | 4.07e-01 | 85.9% | 62.5% |
| 5025931 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 50.0 | 3.90e-01 | 100.0% | 81.0% |
| 4258320 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.59 | 44.0 | 4.40e-01 | 80.8% | 77.5% |
| 5022668 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.59 | 51.0 | 4.28e-01 | 100.0% | 85.0% |
| 3286912 | 632.18.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 | 0.59 | 46.0 | 4.39e-01 | 85.9% | 70.5% |
| 3957876 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.58 | 37.0 | 3.76e-01 | 79.5% | 62.5% |
| 4027595 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.58 | 49.0 | 3.74e-01 | 100.0% | 82.9% |
| 4937236 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.58 | 45.0 | 4.18e-01 | 84.6% | 93.0% |
| 3654456 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.58 | 42.0 | 2.83e-01 | 76.9% | 63.0% |
| 3699443 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.56 | 42.0 | 3.75e-01 | 80.8% | 98.3% |
| 4945441 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.55 | 41.0 | 3.31e-01 | 80.8% | 92.1% |
| 4971237 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.55 | 39.0 | 3.56e-01 | 76.9% | 62.7% |
| 5071140 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.54 | 46.0 | 3.86e-01 | 100.0% | 89.3% |
| 3324694 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.54 | 43.0 | 3.13e-01 | 89.7% | 43.7% |
| 4197862 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.52 | 42.0 | 3.47e-01 | 91.0% | 78.0% |
| 4603998 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.51 | 44.0 | 3.59e-01 | 93.6% | 66.4% |
| 4281647 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.51 | 39.0 | 3.18e-01 | 84.6% | 72.5% |
| 4275140 | 4198.1.1.2 ↗ | alpha arrays › TerB-like › TerB-like › TerB-like › ThylakoidFormat | 0.51 | 42.0 | 3.17e-01 | 93.6% | 65.9% |
D3
medium
residues 80-194
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.75 | 55.0 | 6.12e-01 | 78.3% | 95.7% |
| 6qumQ00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.70 | 42.0 | 5.09e-01 | 79.1% | 93.2% |
| 5lbmA00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.69 | 42.0 | 4.87e-01 | 80.9% | 84.3% |
| 3f0cA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.67 | 46.0 | 4.26e-01 | 72.2% | 55.6% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.67 | 56.0 | 5.70e-01 | 88.7% | 100.0% |
| 3swhA01 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.65 | 58.0 | 5.11e-01 | 97.4% | 99.4% |
| 8b70A01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.64 | 47.0 | 3.22e-01 | 77.4% | 57.4% |
| 2jifA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.63 | 43.0 | 4.29e-01 | 90.4% | 67.8% |
| 5ojcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.63 | 44.0 | 4.03e-01 | 73.0% | 92.2% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 53.0 | 4.53e-01 | 91.3% | 67.6% |
| 2fsfB04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.62 | 44.0 | 3.56e-01 | 73.9% | 74.1% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 40.0 | 3.83e-01 | 80.9% | 57.7% |
| 1rx0C01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.61 | 42.0 | 4.18e-01 | 87.8% | 66.7% |
| 3ce2A03 | 1.10.1370.20 | Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › Oligoendopeptidase f, C-terminal domain | 0.60 | 53.0 | 3.71e-01 | 95.7% | 55.3% |
| 1a00B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 41.0 | 3.83e-01 | 70.4% | 93.2% |
| 16vpA00 | 1.10.1290.10 | Mainly Alpha › Orthogonal Bundle › Conserved core of transcriptional regulatory protein vp16 › Alpha trans-inducing (Alpha-TIF) | 0.60 | 48.0 | 3.53e-01 | 86.1% | 70.1% |
| 1gcvB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 41.0 | 3.92e-01 | 71.3% | 94.9% |
| 1nktA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.59 | 43.0 | 3.69e-01 | 74.8% | 83.6% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.59 | 42.0 | 3.17e-01 | 73.0% | 67.9% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 47.0 | 3.78e-01 | 84.3% | 54.5% |
| 3edvA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 51.0 | 4.39e-01 | 93.9% | 96.7% |
| 3m9vA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.58 | 39.0 | 3.81e-01 | 71.3% | 62.2% |
| 1udyA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.58 | 41.0 | 4.07e-01 | 96.5% | 70.0% |
| 3fhnA01 | 6.10.280.210 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A | 0.58 | 52.0 | 4.44e-01 | 99.1% | 70.7% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.58 | 40.0 | 3.61e-01 | 87.0% | 52.3% |
| 1hbgA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 40.0 | 3.70e-01 | 73.0% | 95.9% |
| 5xdcB01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.57 | 39.0 | 4.01e-01 | 85.2% | 73.0% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.56 | 39.0 | 4.29e-01 | 75.7% | 91.0% |
| 3a7mA01 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.56 | 38.0 | 3.94e-01 | 86.1% | 73.6% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 44.0 | 4.55e-01 | 84.3% | 93.5% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 41.0 | 3.25e-01 | 76.5% | 74.0% |
| 7wf6A01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.55 | 45.0 | 4.25e-01 | 86.1% | 77.0% |
| 1tu9A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 39.0 | 3.78e-01 | 73.0% | 97.7% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 40.0 | 3.14e-01 | 76.5% | 59.8% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.54 | 38.0 | 3.38e-01 | 84.3% | 50.3% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 46.0 | 4.58e-01 | 98.3% | 88.9% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.54 | 40.0 | 3.67e-01 | 90.4% | 58.8% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 42.0 | 4.24e-01 | 83.5% | 99.1% |
| 3urzA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 45.0 | 3.78e-01 | 92.2% | 56.9% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.53 | 42.0 | 3.85e-01 | 93.9% | 63.6% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 41.0 | 4.06e-01 | 83.5% | 96.7% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.52 | 37.0 | 4.17e-01 | 85.2% | 98.8% |
| 4nqfA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.52 | 38.0 | 3.59e-01 | 77.4% | 88.3% |
| 6zhiB02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.52 | 33.0 | 3.80e-01 | 70.4% | 89.2% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.51 | 40.0 | 3.80e-01 | 80.9% | 75.2% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3896892 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.76 | 55.0 | 5.12e-01 | 100.0% | 60.0% |
| 4032308 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.71 | 49.0 | 4.23e-01 | 70.4% | 57.1% |
| 3192900 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.68 | 63.0 | 4.17e-01 | 100.0% | 63.9% |
| 4550741 | 106.1.1.7 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Protoglobin | 0.66 | 46.0 | 4.00e-01 | 70.4% | 82.9% |
| 3916954 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.66 | 48.0 | 4.43e-01 | 74.8% | 95.2% |
| 3697996 | 7013.1.1.1 ↗ | alpha bundles › Ribosome assembly factor Efg1-like › Ribosome assembly factor Efg1-like › Ribosome assembly factor Efg1-like › Efg1 | 0.66 | 46.0 | 3.85e-01 | 71.3% | 95.8% |
| 3924049 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.65 | 43.0 | 3.63e-01 | 77.4% | 41.1% |
| 3258661 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.64 | 53.0 | 4.36e-01 | 87.8% | 77.1% |
| 3957336 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.64 | 45.0 | 4.83e-01 | 73.9% | 92.0% |
| 3942460 | 5067.1.1.1 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ACR_tran | 0.62 | 56.0 | 4.56e-01 | 100.0% | 81.8% |
| 5021445 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.62 | 47.0 | 4.73e-01 | 92.2% | 79.1% |
| 3740238 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.62 | 47.0 | 4.19e-01 | 78.3% | 77.4% |
| 4944595 | 1197.1.1.1 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf | 0.61 | 49.0 | 3.94e-01 | 87.8% | 68.1% |
| 50988 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.60 | 41.0 | 3.83e-01 | 70.4% | 93.2% |
| 53474 | 4033.1.1.0 ↗ | alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like | 0.60 | 42.0 | 4.20e-01 | 85.2% | 68.6% |
| 3737956 | 601.19.1.18 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Mmc1_C | 0.60 | 46.0 | 3.83e-01 | 80.0% | 80.5% |
| 5076993 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.60 | 46.0 | 4.28e-01 | 81.7% | 94.5% |
| 3964012 | 3831.1.1.1 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI | 0.60 | 41.0 | 4.23e-01 | 87.8% | 73.6% |
| 5059560 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.58 | 48.0 | 3.48e-01 | 92.2% | 32.7% |
| 3585743 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.57 | 43.0 | 3.84e-01 | 79.1% | 92.1% |
| 3164389 | 1079.1.1.11 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › NicO | 0.57 | 47.0 | 3.79e-01 | 91.3% | 80.8% |
| 3629933 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.57 | 43.0 | 3.74e-01 | 79.1% | 86.9% |
| 3718430 | 1065.1.1.0 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain | 0.57 | 51.0 | 4.49e-01 | 97.4% | 81.2% |
| 3492033 | 5001.1.1.142 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF716 | 0.57 | 42.0 | 3.39e-01 | 77.4% | 71.5% |
| 3273377 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.57 | 40.0 | 3.21e-01 | 72.2% | 67.0% |
| 3941457 | 1203.1.2.3 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › YiaAB | 0.57 | 44.0 | 4.41e-01 | 90.4% | 80.0% |
| 4967067 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.56 | 42.0 | 4.22e-01 | 90.4% | 78.3% |
| 169450 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.56 | 42.0 | 4.14e-01 | 87.8% | 71.9% |
| 3527324 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.56 | 41.0 | 4.02e-01 | 75.7% | 92.8% |
| 5076610 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 44.0 | 3.56e-01 | 83.5% | 75.5% |
| 3629471 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.55 | 39.0 | 3.24e-01 | 73.9% | 57.1% |
| 4660205 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.55 | 41.0 | 3.91e-01 | 76.5% | 79.3% |
| 3577232 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 43.0 | 4.24e-01 | 84.3% | 91.2% |
| 3225077 | 371.1.1.0 ↗ | few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 | 0.55 | 46.0 | 4.82e-01 | 96.5% | 100.0% |
| 3576825 | 109.4.1.1635 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26779 | 0.55 | 36.0 | 2.99e-01 | 73.0% | 34.2% |
| 3973646 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.55 | 39.0 | 3.51e-01 | 88.7% | 53.1% |
| 3492279 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.53 | 40.0 | 4.09e-01 | 80.0% | 83.5% |
| 3629105 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.53 | 45.0 | 4.04e-01 | 93.0% | 66.9% |
| 4054050 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.53 | 37.0 | 3.98e-01 | 82.6% | 84.0% |
| 3488061 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 43.0 | 3.46e-01 | 89.6% | 74.3% |
| 3419686 | 3755.4.1.46 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › NET2A | 0.52 | 40.0 | 3.49e-01 | 81.7% | 82.2% |
| 5041130 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.52 | 45.0 | 4.40e-01 | 94.8% | 89.6% |
| 3615123 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 41.0 | 3.48e-01 | 81.7% | 66.1% |
| 3518412 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.52 | 40.0 | 3.23e-01 | 81.7% | 69.8% |
| 3621149 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.52 | 39.0 | 3.13e-01 | 79.1% | 62.7% |
| 4377277 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.51 | 42.0 | 3.80e-01 | 92.2% | 81.2% |
D4
medium
residues 344-440
Domain cluster:
representative
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4984022 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.83 | 63.0 | 5.88e-01 | 85.6% | 65.8% |
| 4475763 | 3755.1.1.11 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › She9_MDM33 | 0.79 | 62.0 | 4.71e-01 | 92.8% | 38.5% |
| 3997665 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.77 | 59.0 | 5.54e-01 | 88.7% | 67.3% |
| 4027031 | 109.4.1.95 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2 | 0.77 | 51.0 | 3.83e-01 | 75.3% | 29.3% |
| 3447356 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.76 | 65.0 | 5.89e-01 | 92.8% | 70.4% |
| 4008053 | 4168.1.1.7 ↗ | alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain › PF26769 | 0.74 | 60.0 | 4.97e-01 | 86.6% | 81.2% |
| 5030599 | 192.15.1.226 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › CdvA | 0.70 | 55.0 | 4.91e-01 | 81.4% | 60.8% |
| 5064159 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.69 | 48.0 | 3.72e-01 | 73.2% | 52.7% |
| 3649758 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.65 | 52.0 | 4.02e-01 | 91.8% | 37.8% |
| 3533245 | 192.15.1.2 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r | 0.59 | 54.0 | 4.55e-01 | 99.0% | 70.6% |