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MN871446.1__UKS72115.1__KpLz245_2490__00249

Bact-Vir

MN871446.1__UKS72115.1__KpLz245_2490__00249

Identity

Accession:
MN871446 ↗
Kingdom:
phage

Quality

73.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-18_100-136
PDB
Domain cluster: representative
CATH (71)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2fpoC00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.71 52.0 3.65e-01 92.7% 24.3%
2rhqB06 3.30.70.380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ferrodoxin-fold anticodon-binding domain 0.67 56.0 4.93e-01 94.5% 66.3%
1xrsB01 3.30.30.60 Alpha Beta › 2-Layer Sandwich › Defensin A-like › D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain 0.66 52.0 5.30e-01 85.5% 100.0%
1j5uA01 3.55.10.10 Alpha Beta › 3-Layer(bab) Sandwich › Archease, Possible Chaperone; Chain: A; domain 1 › Archease domain 0.64 50.0 4.06e-01 90.9% 46.2%
2p4gA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.63 52.0 3.42e-01 92.7% 23.0%
2wnyA00 3.30.1440.10 Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 0.62 51.0 3.99e-01 100.0% 46.7%
3ibwA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.61 51.0 4.65e-01 98.2% 68.4%
2jnaA01 3.30.1660.10 Alpha Beta › 2-Layer Sandwich › Dodecin subunit-like › Flavin-binding protein dodecin 0.61 49.0 4.65e-01 94.5% 87.0%
4kzsA01 3.10.28.20 Alpha Beta › Roll › Endonuclease I-creI › Acetamidase/Formamidase-like domains 0.60 48.0 4.38e-01 90.9% 100.0%
2bj3D02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.60 50.0 4.48e-01 98.2% 69.1%
1darA05 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 49.0 4.33e-01 94.5% 97.7%
2zfuA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 48.0 3.59e-01 94.5% 32.3%
3qwuA03 3.30.70.2160 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 48.0 3.75e-01 98.2% 77.0%
3ky8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.59 46.0 3.28e-01 87.3% 28.7%
4clfA02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.58 46.0 3.36e-01 94.5% 35.9%
1j6wA00 3.30.1360.80 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › S-ribosylhomocysteinase (LuxS) 0.58 47.0 3.30e-01 87.3% 40.4%
6lxgA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.58 44.0 4.11e-01 87.3% 68.5%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.58 49.0 3.81e-01 98.2% 49.2%
4xt6A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.58 46.0 3.08e-01 89.1% 22.4%
4evuB00 3.30.1660.10 Alpha Beta › 2-Layer Sandwich › Dodecin subunit-like › Flavin-binding protein dodecin 0.58 46.0 4.39e-01 92.7% 82.4%
3fncB00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.58 43.0 3.27e-01 89.1% 29.8%
3juwA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.58 44.0 3.23e-01 92.7% 28.7%
3rrkA03 3.30.70.2750 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 46.0 4.27e-01 94.5% 70.3%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.57 47.0 3.84e-01 100.0% 58.5%
5tvfD00 3.60.90.10 Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase 0.57 46.0 3.05e-01 96.4% 58.9%
3mtjA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.57 44.0 4.07e-01 92.7% 65.8%
2dt9A01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.57 44.0 4.03e-01 85.5% 68.9%
3n79A01 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.56 43.0 3.96e-01 90.9% 62.8%
4pg4B03 3.30.70.3100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 45.0 4.19e-01 98.2% 68.0%
3v8hC00 3.30.572.10 Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain 0.56 46.0 3.03e-01 100.0% 34.0%
2ewhA01 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.56 44.0 3.95e-01 92.7% 60.0%
4kvxA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.56 43.0 3.25e-01 90.9% 32.2%
2go8A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 44.0 4.11e-01 98.2% 68.9%
4ushA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 47.0 3.94e-01 100.0% 52.4%
3gnlA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 42.0 3.15e-01 90.9% 29.7%
2qmlA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.56 42.0 3.03e-01 92.7% 25.4%
4u9rA02 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 42.0 4.04e-01 83.6% 75.4%
2lxrA00 3.30.110.40 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › TusA-like domain 0.55 42.0 3.91e-01 89.1% 65.8%
4d9uA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.55 41.0 3.56e-01 81.8% 55.7%
1u6mA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.55 42.0 3.04e-01 90.9% 25.9%
2re1A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.55 42.0 3.94e-01 94.5% 67.6%
4feuF01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.55 42.0 3.85e-01 83.6% 69.9%
1vdhA01 3.30.70.1030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1 0.55 45.0 3.66e-01 100.0% 55.4%
4ctaA02 3.30.70.2860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 44.0 4.09e-01 100.0% 70.7%
1vx4407 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 39.0 3.78e-01 87.3% 66.7%
1xdxA01 3.30.1140.40 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 0.54 42.0 3.61e-01 90.9% 51.0%
4pcqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.54 47.0 4.08e-01 96.4% 66.7%
2cg4A02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.54 47.0 4.06e-01 96.4% 64.3%
3im9A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.54 42.0 3.90e-01 94.5% 67.6%
6bg2A02 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.54 42.0 3.28e-01 87.3% 46.4%
2j0wA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.53 42.0 3.84e-01 94.5% 64.2%
3dlsB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.53 41.0 3.47e-01 87.3% 58.2%
1m0sA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.53 40.0 3.82e-01 90.9% 68.1%
5suhB01 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.53 41.0 3.55e-01 92.7% 51.5%
2dbbA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.52 39.0 3.51e-01 100.0% 53.8%
2zzeA04 3.30.980.10 Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Threonyl-trna Synthetase; Chain A, domain 2 0.52 43.0 3.69e-01 94.5% 97.9%
4js8A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 40.0 3.51e-01 87.3% 66.3%
6fucA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 38.0 3.34e-01 80.0% 59.3%
2b4vA03 3.30.70.1970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 38.0 3.35e-01 87.3% 50.5%
4wnoA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 40.0 3.46e-01 83.6% 62.1%
4fg9A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 39.0 3.48e-01 81.8% 57.0%
2yweA03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.52 39.0 3.62e-01 92.7% 68.3%
1yk3B00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.52 39.0 2.88e-01 98.2% 26.4%
5cemA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 39.0 3.55e-01 81.8% 61.6%
6n3oA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 43.0 3.69e-01 96.4% 61.1%
4h05B01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 38.0 3.30e-01 83.6% 57.1%
1zysA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 39.0 3.35e-01 87.3% 60.0%
1dn0D02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 39.0 3.45e-01 94.5% 58.5%
2rioA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.50 37.0 3.29e-01 80.0% 61.0%
4crsA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.50 39.0 3.01e-01 87.3% 46.3%
2rkuA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.50 42.0 3.67e-01 98.2% 62.9%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5000808 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.70 58.0 6.05e-01 98.2% 100.0%
5004176 256.1.1.0 a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like 0.69 58.0 5.81e-01 96.4% 100.0%
5054210 304.24.1.6 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › SBDS_C 0.69 58.0 5.09e-01 98.2% 62.5%
3174687 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.68 55.0 5.01e-01 94.5% 66.7%
3964190 310.3.1.3 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related › PilN 0.68 59.0 4.16e-01 96.4% 33.3%
3679423 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.67 55.0 5.06e-01 94.5% 70.7%
4569098 304.18.1.0 a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS 0.67 57.0 5.42e-01 100.0% 86.8%
3328050 304.8.1.57 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_ACR_D1 0.67 53.0 4.90e-01 92.7% 69.3%
4507345 304.18.1.0 a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS 0.66 56.0 5.04e-01 100.0% 71.2%
4438073 304.18.1.0 a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS 0.66 56.0 5.00e-01 100.0% 71.1%
3330441 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.66 54.0 4.95e-01 94.5% 72.0%
3660837 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.66 55.0 4.84e-01 96.4% 65.9%
5049188 872.5.1.1 a+b two layers › Dodecin subunit-like › D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain › D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain › OAM_dimer 0.66 57.0 5.07e-01 98.2% 73.8%
4995076 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.66 57.0 3.78e-01 98.2% 63.1%
4943523 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.66 56.0 4.39e-01 100.0% 80.8%
4067169 304.52.1.1 a+b two layers › Alpha-beta plaits › YbeD/HP0495-like › YbeD/HP0495-like › DUF493 0.66 54.0 4.82e-01 98.2% 67.1%
3678575 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.65 53.0 5.37e-01 94.5% 98.2%
3890461 2003.1.5.46 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.65 55.0 3.50e-01 96.4% 19.0%
3367471 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.65 54.0 5.05e-01 96.4% 75.7%
3666529 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 55.0 4.86e-01 100.0% 67.1%
4941246 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 54.0 4.99e-01 92.7% 74.3%
5057437 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.65 53.0 3.57e-01 94.5% 25.2%
3164985 310.3.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.65 53.0 3.86e-01 92.7% 31.9%
3810458 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 53.0 4.51e-01 94.5% 56.8%
4930625 2.1.1.95 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Lig_C 0.65 54.0 4.16e-01 98.2% 79.3%
3837690 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.65 51.0 4.76e-01 92.7% 72.0%
3382243 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 53.0 5.34e-01 92.7% 98.1%
4288222 328.6.1.1 a+b two layers › IF3-like › EPT/RTPC-like › EPT/RTPC-like › EPSP_synthase 0.65 54.0 3.64e-01 98.2% 34.8%
3425342 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 51.0 4.77e-01 94.5% 73.3%
4966477 304.18.1.0 a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS 0.64 56.0 4.72e-01 100.0% 61.1%
3642698 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.63 51.0 5.18e-01 96.4% 100.0%
3267514 328.3.1.0 a+b two layers › IF3-like › Translation initiation factor IF3, C-terminal domain › Translation initiation factor IF3, C-terminal domain 0.63 51.0 4.25e-01 98.2% 100.0%
3433964 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.63 51.0 5.17e-01 100.0% 94.5%
3383879 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.62 49.0 4.58e-01 92.7% 72.0%
4955435 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.62 51.0 4.65e-01 92.7% 69.3%
3970104 310.3.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.62 51.0 4.50e-01 90.9% 96.2%
3305323 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 49.0 4.57e-01 94.5% 70.7%
4341311 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.61 48.0 4.26e-01 92.7% 58.9%
3655963 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 50.0 4.77e-01 100.0% 77.1%
3241748 256.1.1.0 a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like 0.60 47.0 4.73e-01 96.4% 90.9%
3518762 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.60 46.0 4.67e-01 90.9% 96.4%
136544 304.8.1.8 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_4 0.60 49.0 4.48e-01 98.2% 68.8%
2165976 310.3.1.4 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related › GspL_C 0.60 51.0 4.53e-01 96.4% 100.0%
3553500 2003.1.5.79 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.60 48.0 3.13e-01 96.4% 19.0%
3375878 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.59 49.0 4.54e-01 100.0% 72.0%
4256963 387.1.5.0 few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like 0.59 44.0 4.65e-01 81.8% 100.0%
3780610 2003.1.5.320 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PrmA, Methyltransf_16 0.59 47.0 3.08e-01 96.4% 19.7%
5043269 304.130.1.1 a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.59 47.0 4.27e-01 98.2% 67.1%
3430598 387.1.5.31 few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like › PF29352 0.58 43.0 4.45e-01 83.6% 100.0%
3420578 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.58 46.0 3.16e-01 92.7% 22.7%
3641084 387.1.5.31 few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like › PF29352 0.58 43.0 4.40e-01 85.5% 100.0%
4028723 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.57 47.0 4.48e-01 92.7% 80.0%
4940258 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.57 45.0 4.26e-01 85.5% 75.4%
3811780 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.57 45.0 3.70e-01 94.5% 47.8%
3195848 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.56 43.0 3.89e-01 85.5% 61.3%
3659690 387.1.5.31 few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like › PF29352 0.56 41.0 4.32e-01 80.0% 100.0%
4059207 2003.1.5.25 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GidB 0.56 43.0 3.04e-01 92.7% 24.0%
3260875 206.1.1.73 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, APH 0.56 44.0 2.88e-01 89.1% 39.6%
152843 328.5.1.2 a+b two layers › IF3-like › SirA-like › SirA-like › NADH-UOR_E 0.55 42.0 3.91e-01 89.1% 65.8%
4075546 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.55 43.0 3.82e-01 96.4% 57.8%
3003835 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.54 44.0 3.72e-01 100.0% 73.4%
4953585 3501.1.1.0 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 0.54 44.0 3.98e-01 90.9% 68.0%
4937853 3501.1.1.0 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 0.54 41.0 3.82e-01 98.2% 65.7%
3808909 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.54 44.0 4.47e-01 100.0% 96.4%
5262 304.8.1.21 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.54 41.0 4.02e-01 90.9% 78.1%
3974171 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.54 43.0 3.80e-01 100.0% 58.9%
4069329 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.54 41.0 3.77e-01 100.0% 62.5%
4438356 304.162.1.0 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.53 43.0 4.03e-01 100.0% 70.7%
3164749 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.53 42.0 3.75e-01 100.0% 58.9%
4019036 304.3.1.15 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › PF31052 0.53 42.0 3.91e-01 96.4% 68.6%
4589697 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.53 41.0 3.78e-01 94.5% 67.5%
4682556 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.53 43.0 3.90e-01 100.0% 66.3%
3466526 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.53 42.0 4.13e-01 94.5% 81.2%
4081991 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.53 39.0 3.86e-01 89.1% 78.3%
5021160 327.11.2.82 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF27275 0.53 41.0 3.66e-01 92.7% 63.3%
4398464 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.52 39.0 3.64e-01 100.0% 62.5%
3824796 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.52 41.0 3.87e-01 96.4% 73.9%
3427796 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.51 39.0 3.48e-01 92.7% 56.7%
3812850 387.1.5.15 few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like › SLR1-BP 0.51 38.0 4.02e-01 94.5% 100.0%
3195250 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.50 37.0 2.67e-01 87.3% 23.3%
3249237 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.50 41.0 3.25e-01 94.5% 41.6%
D2 medium residues 19-99
PDB
Domain cluster: representative
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1t3qA02 1.10.150.120 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › [2Fe-2S]-binding domain 0.71 52.0 5.28e-01 97.5% 77.8%
7wivA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 61.0 4.16e-01 98.8% 50.2%
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.66 52.0 4.71e-01 87.7% 63.5%
8b70A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.66 53.0 3.41e-01 90.1% 54.3%
3s0xA01 1.20.120.1220 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 49.0 4.10e-01 82.7% 87.8%
1gvfB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.65 45.0 3.13e-01 72.8% 89.5%
2yksA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.63 48.0 4.35e-01 84.0% 88.0%
7xpzA01 1.20.1720.10 Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D 0.62 45.0 2.93e-01 77.8% 67.0%
7d5qA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.62 43.0 3.38e-01 72.8% 78.0%
2qptA01 1.10.268.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › 0.62 52.0 4.37e-01 96.3% 63.0%
1a3qA01 2.60.40.340 Mainly Beta › Sandwich › Immunoglobulin-like › Rel homology domain (RHD), DNA-binding domain 0.60 43.0 3.31e-01 74.1% 47.5%
4b4yA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 52.0 4.35e-01 100.0% 98.7%
4a64C03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.60 45.0 4.26e-01 85.2% 66.0%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.59 42.0 3.51e-01 74.1% 81.4%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.59 47.0 3.93e-01 90.1% 62.7%
1yhuB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 51.0 4.28e-01 100.0% 98.6%
3ckdA02 1.20.58.360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines 0.58 44.0 3.86e-01 81.5% 91.9%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.58 48.0 4.35e-01 96.3% 88.8%
4bouA00 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.57 39.0 3.32e-01 71.6% 76.6%
4akgA08 1.10.472.130 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain 0.56 44.0 3.59e-01 85.2% 44.2%
7zh0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 49.0 3.16e-01 100.0% 22.5%
3acxA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.55 45.0 3.18e-01 92.6% 82.4%
6ldkA01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.55 45.0 3.63e-01 93.8% 68.6%
1hciA04 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 40.0 3.68e-01 81.5% 78.1%
2fu2A00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.54 41.0 4.21e-01 91.4% 85.9%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.54 40.0 3.53e-01 82.7% 81.2%
3d85C00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 45.0 3.95e-01 98.8% 91.0%
3l09A01 1.20.58.1460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 40.0 3.81e-01 81.5% 69.4%
1wvuA01 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.52 39.0 3.21e-01 79.0% 70.3%
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.52 41.0 3.42e-01 87.7% 79.5%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.52 39.0 3.83e-01 81.5% 87.5%
4ibnA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.52 44.0 3.35e-01 93.8% 76.1%
2wl8C00 1.20.120.900 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pex19, mPTS binding domain 0.51 38.0 3.57e-01 84.0% 84.4%
3rguB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.51 36.0 3.61e-01 76.5% 85.1%
4akgA06 1.10.8.710 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Dynein motor, AAA1 domain, small subdomain 0.51 40.0 3.75e-01 90.1% 71.0%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.50 35.0 3.66e-01 75.3% 86.7%
1chuA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.50 37.0 3.69e-01 81.5% 78.4%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3607719 633.24.1.0 alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain 0.74 64.0 6.31e-01 96.3% 95.3%
3925681 633.24.1.2 alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › DUF5601 0.73 62.0 5.99e-01 92.6% 87.8%
3888089 633.24.1.2 alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › DUF5601 0.72 60.0 5.45e-01 91.4% 72.7%
4488191 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.72 57.0 5.12e-01 86.4% 68.7%
3622208 633.24.1.2 alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › DUF5601 0.71 59.0 5.47e-01 91.4% 76.2%
3348585 1075.4.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 0.70 61.0 4.10e-01 100.0% 82.2%
4611743 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.69 55.0 5.40e-01 95.1% 80.0%
3190830 706.1.1.0 beta complex topology › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE 0.69 60.0 4.18e-01 97.5% 59.2%
3993765 627.1.1.0 alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain 0.66 56.0 5.53e-01 98.8% 91.8%
3255340 223.2.1.21 a+b three layers › Profilin-like › profilin-like › profilin-like › AP-5_subunit_s1 0.63 45.0 3.41e-01 74.1% 64.3%
4017306 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.63 44.0 4.43e-01 71.6% 82.5%
4027010 509.1.1.0 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain 0.62 53.0 4.49e-01 97.5% 73.6%
4983425 2004.1.1.42 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.60 51.0 3.24e-01 98.8% 30.2%
3924866 170.1.1.0 alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C 0.59 42.0 4.01e-01 77.8% 64.2%
3429164 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 42.0 3.99e-01 76.5% 77.9%
5031845 4275.1.1.0 alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like 0.57 37.0 3.86e-01 87.7% 72.0%
3195747 3788.1.1.0 alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) 0.56 40.0 4.26e-01 100.0% 88.6%
5056219 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.55 42.0 2.83e-01 85.2% 24.3%
5009804 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.55 42.0 4.01e-01 82.7% 75.8%
5001838 140.1.1.14 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e 0.54 41.0 3.46e-01 84.0% 45.3%
5026462 5060.1.1.1 alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C › vATP-synt_AC39 0.54 41.0 3.60e-01 81.5% 79.2%
3813129 3787.3.1.1 alpha bundles › HAD superfamily helical bundle insertion domain › Insertion domain in cytosolic IMP-GMP specific 5'-nucleotidase › Insertion domain in cytosolic IMP-GMP specific 5'-nucleotidase › 5_nucleotid 0.54 47.0 3.83e-01 97.5% 85.2%
4118017 4336.2.1.1 alpha duplicates or obligate multimers › YheA/YmcA-like › Protein SUS1 › Protein SUS1 › EnY2 0.54 37.0 3.51e-01 70.4% 81.0%
3427035 622.1.1.30 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › PF26575 0.54 40.0 4.33e-01 80.2% 98.5%
3807085 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.52 39.0 3.92e-01 82.7% 85.9%
3505438 604.1.1.67 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_5 0.51 38.0 3.57e-01 81.5% 85.0%
3717093 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.51 36.0 3.88e-01 96.3% 88.6%