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MN988538.1__QIG74522.1__EVC10_014__00014

Bact-Vir

MN988538.1__QIG74522.1__EVC10_014__00014

Identity

Accession:
MN988538 ↗
Kingdom:
phage

Quality

74.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 42-178
PDB
D2 medium residues 201-219_584-622
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2psmA00 1.20.1250.70 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 0.79 51.0 4.04e-01 98.3% 33.3%
4fvmA06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.79 48.0 5.23e-01 91.4% 75.0%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.72 50.0 4.10e-01 96.6% 41.2%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.71 53.0 4.86e-01 100.0% 61.0%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 48.0 4.48e-01 100.0% 57.5%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.69 45.0 3.50e-01 94.8% 29.3%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 51.0 3.54e-01 100.0% 24.2%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.66 50.0 4.11e-01 96.6% 44.0%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.66 46.0 4.48e-01 93.1% 66.2%
3no6A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.66 53.0 3.52e-01 89.7% 91.1%
4hfkB00 1.20.120.1620 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 41.0 3.44e-01 86.2% 37.8%
1uaaA02 1.10.10.160 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.64 42.0 3.94e-01 98.3% 54.1%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.63 53.0 3.98e-01 96.6% 90.7%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 45.0 4.44e-01 100.0% 75.8%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.61 51.0 4.67e-01 98.3% 70.5%
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.61 48.0 4.41e-01 100.0% 65.0%
3ecqA07 6.10.140.660 Special › Helix non-globular › Helix Hairpins › 0.59 33.0 3.68e-01 84.5% 68.9%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.59 53.0 4.56e-01 100.0% 77.8%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 43.0 3.18e-01 82.8% 30.2%
1eupA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.59 48.0 3.02e-01 100.0% 36.2%
3besR03 6.10.140.1480 Special › Helix non-globular › Helix Hairpins › 0.58 46.0 4.73e-01 100.0% 89.3%
7miqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 40.0 3.33e-01 100.0% 40.0%
2v4jA01 6.10.140.1420 Special › Helix non-globular › Helix Hairpins › 0.57 37.0 3.67e-01 100.0% 61.9%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.57 50.0 4.78e-01 98.3% 85.1%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.56 49.0 4.57e-01 100.0% 95.9%
2mpnA00 6.10.140.1340 Special › Helix non-globular › Helix Hairpins › 0.56 44.0 4.26e-01 93.1% 75.0%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 45.0 4.36e-01 86.2% 81.0%
1gvfB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.56 40.0 2.65e-01 82.8% 16.7%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.55 47.0 4.39e-01 100.0% 75.3%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.55 47.0 4.53e-01 96.6% 85.3%
2oxlA00 1.20.5.5260 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.54 43.0 4.27e-01 89.7% 100.0%
2i39B00 1.10.437.20 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus 0.53 41.0 3.31e-01 86.2% 82.4%
4xi0F00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 44.0 3.14e-01 93.1% 39.9%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.53 43.0 4.07e-01 96.6% 73.0%
4l6v600 1.10.8.110 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Photosystem I, reaction centre, subunit PsaF 0.52 41.0 3.29e-01 89.7% 45.6%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4576287 3755.3.1.471 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Paralemmin 0.75 52.0 3.81e-01 100.0% 27.1%
57654 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.75 51.0 5.27e-01 100.0% 75.9%
2617307 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.75 51.0 3.15e-01 100.0% 12.5%
4041347 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.73 50.0 4.08e-01 100.0% 38.2%
3418094 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.72 50.0 4.51e-01 100.0% 52.5%
5053661 2011.1.1.8 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 0.72 54.0 3.28e-01 100.0% 12.8%
4936497 150.1.1.14 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › EncFtn-like 0.71 49.0 4.33e-01 100.0% 47.7%
5048590 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.71 49.0 4.02e-01 100.0% 38.2%
4221982 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.71 49.0 4.13e-01 100.0% 42.0%
3497934 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.71 49.0 3.23e-01 100.0% 16.8%
3692897 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.70 48.0 4.50e-01 100.0% 56.0%
3884649 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.70 48.0 4.16e-01 100.0% 44.2%
3550436 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.67 46.0 3.89e-01 100.0% 40.4%
3170882 603.1.1.210 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Tmemb_170 0.66 49.0 3.84e-01 98.3% 38.3%
2524661 3932.1.1.2 alpha bundles › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain › Cas_Csm6_6H 0.63 42.0 4.09e-01 94.8% 61.5%
3756948 601.19.1.17 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Niban2 0.62 54.0 3.87e-01 98.3% 59.4%
3414767 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.60 53.0 4.78e-01 100.0% 83.7%
3973453 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.58 51.0 4.63e-01 100.0% 78.8%
3996264 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.58 49.0 3.57e-01 100.0% 32.9%
4950585 632.8.1.34 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › HisKA 0.57 50.0 4.67e-01 98.3% 95.9%
3894567 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.57 49.0 3.45e-01 100.0% 67.9%
4441096 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.57 40.0 4.00e-01 98.3% 70.0%
3530101 601.19.1.17 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Niban2 0.57 45.0 2.89e-01 86.2% 90.6%
3409567 3755.3.1.324 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 0.56 49.0 3.54e-01 100.0% 37.0%
3378723 650.1.1.0 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain 0.56 47.0 4.28e-01 94.8% 90.0%
4979981 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.56 49.0 3.97e-01 100.0% 62.7%
3961229 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.55 48.0 3.36e-01 100.0% 44.7%
3288075 2004.1.1.600 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn, AAA_21 0.54 47.0 2.75e-01 100.0% 16.5%
3343253 109.26.1.6 alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › TPR_NUP160_120_M 0.53 46.0 3.09e-01 98.3% 36.1%
3206303 3722.1.1.1 alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › MAP65_ASE1 0.52 45.0 3.14e-01 100.0% 31.0%
D3 medium residues 220-291_481-540
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.67 38.0 4.89e-01 74.2% 100.0%
2nnwA02 1.10.287.4070 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 46.0 4.67e-01 71.2% 98.4%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 45.0 4.93e-01 89.4% 88.6%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 44.0 5.01e-01 93.2% 94.8%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 47.0 4.99e-01 93.2% 86.3%
7miqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 39.0 4.22e-01 87.9% 76.4%
1a7mA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.60 44.0 3.98e-01 75.8% 69.4%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.60 42.0 3.52e-01 71.2% 88.3%
2a3qA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.60 37.0 4.00e-01 76.5% 71.7%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.59 37.0 3.70e-01 84.1% 59.9%
3d85C00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.59 47.0 4.69e-01 89.4% 82.0%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 46.0 4.23e-01 82.6% 86.9%
1mabG00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.58 40.0 4.15e-01 71.2% 75.0%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.57 49.0 4.62e-01 93.2% 75.6%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.57 42.0 4.58e-01 93.2% 91.8%
4qgpB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.57 35.0 3.84e-01 76.5% 74.8%
3ibhA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 37.0 3.90e-01 84.1% 74.6%
4jioA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.56 36.0 3.56e-01 70.5% 60.1%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.55 49.0 4.15e-01 98.5% 87.4%
1t02A02 3.90.770.10 Alpha Beta › Alpha-Beta Complex › 3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2 › 3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2 0.55 45.0 3.68e-01 90.9% 96.9%
4mhlA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 46.0 4.31e-01 95.5% 77.6%
3smtA02 3.90.1420.10 Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain 0.52 47.0 4.36e-01 98.5% 97.6%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.52 47.0 3.49e-01 98.5% 90.2%
4d8mA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.52 43.0 3.68e-01 92.4% 55.6%
3x29A00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.50 42.0 3.95e-01 91.7% 92.8%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3857618 633.23.1.4 alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_2 0.68 47.0 4.01e-01 70.5% 100.0%
4969098 3926.1.1.0 alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D 0.66 40.0 3.65e-01 72.0% 45.1%
4019589 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.66 46.0 3.68e-01 70.5% 77.2%
3464273 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.66 50.0 5.21e-01 93.9% 87.5%
4018949 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.65 40.0 3.45e-01 83.3% 39.0%
3746634 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.64 48.0 4.92e-01 93.2% 81.6%
3953372 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.64 37.0 4.19e-01 70.5% 74.5%
3253207 1065.1.1.1 alpha bundles › SPX domain › SPX domain › SPX domain › SPX 0.61 46.0 4.10e-01 93.2% 53.8%
3539926 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.61 53.0 4.48e-01 94.7% 71.6%
3332592 5069.1.1.62 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Chloroplast_duf 0.60 39.0 4.17e-01 86.4% 76.4%
3518412 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.59 41.0 3.45e-01 71.2% 71.1%
4946897 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.59 50.0 4.57e-01 90.9% 87.6%
4012748 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.59 51.0 3.84e-01 93.2% 40.6%
3396167 633.12.1.13 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › Piezo_TM1-24 0.58 43.0 4.05e-01 76.5% 85.0%
4500653 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.56 42.0 4.09e-01 78.8% 70.0%
4015520 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.56 50.0 4.70e-01 98.5% 87.3%
4019360 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 39.0 3.63e-01 70.5% 76.9%
4013484 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.56 51.0 4.38e-01 99.2% 70.7%
4009605 601.41.1.3 alpha bundles › Four-helical up-and-down bundle › C-terminal domain in uncharacterized DUF3829-like protein › C-terminal domain in uncharacterized DUF3829-like protein › DUF3829 0.56 40.0 3.97e-01 100.0% 71.9%
4520789 1204.1.1.0 alpha bundles › Bacteriocin pyocin-S2 N-terminal domain › Bacteriocin pyocin-S2 N-terminal domain › Bacteriocin pyocin-S2 N-terminal domain 0.55 50.0 4.28e-01 100.0% 75.2%
4164723 101.1.2.598 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, POLR3C_WHD 0.55 41.0 2.80e-01 75.8% 63.1%
4013791 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.54 47.0 4.13e-01 100.0% 64.0%
3285241 192.29.1.52 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy 0.54 42.0 3.97e-01 91.7% 67.3%
3190578 1065.1.1.1 alpha bundles › SPX domain › SPX domain › SPX domain › SPX 0.54 45.0 4.68e-01 92.4% 99.2%
3869365 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.53 47.0 4.58e-01 97.7% 89.3%
3476613 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.53 42.0 4.39e-01 93.2% 93.3%
3412001 633.23.1.4 alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_2 0.52 46.0 3.91e-01 97.7% 85.1%
3165978 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.52 42.0 3.89e-01 89.4% 69.1%
D4 medium residues 292-320_415-480
PDB
Domain cluster: representative
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kplA00 1.10.3080.10 Mainly Alpha › Orthogonal Bundle › Clc chloride channel › Clc chloride channel 0.77 50.0 3.17e-01 71.6% 14.7%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 49.0 3.63e-01 100.0% 26.5%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.73 55.0 4.63e-01 80.0% 90.5%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.72 46.0 4.47e-01 95.8% 57.4%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.72 52.0 5.25e-01 83.2% 75.8%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.71 43.0 5.32e-01 91.6% 100.0%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 46.0 4.65e-01 95.8% 64.9%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.71 46.0 4.48e-01 95.8% 60.2%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.71 47.0 4.57e-01 96.8% 61.3%
5lbmA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.70 52.0 5.49e-01 76.8% 100.0%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.69 46.0 3.95e-01 98.9% 42.0%
6p6jB01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.68 47.0 3.28e-01 100.0% 21.7%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 51.0 4.59e-01 78.9% 57.7%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.67 47.0 4.95e-01 82.1% 80.5%
1rqgA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.66 44.0 3.74e-01 94.7% 42.4%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 44.0 4.31e-01 96.8% 63.6%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 48.0 4.61e-01 97.9% 69.7%
1u00A02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 42.0 4.26e-01 92.6% 67.7%
4nkwA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.63 55.0 3.58e-01 100.0% 67.2%
3nkuA00 1.10.357.170 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.63 40.0 3.33e-01 72.6% 34.7%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 49.0 4.75e-01 98.9% 77.6%
8amqA02 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.60 52.0 3.54e-01 100.0% 68.3%
1cmjA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.60 52.0 3.48e-01 98.9% 70.4%
4al0A00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.59 51.0 4.38e-01 92.6% 91.1%
3ezuA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 46.0 3.74e-01 85.3% 96.2%
3teqB00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 48.0 4.74e-01 100.0% 84.2%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 45.0 4.19e-01 83.2% 67.8%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 41.0 3.57e-01 76.8% 81.9%
2p1aB01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.57 46.0 3.98e-01 87.4% 83.6%
4hhrA01 1.10.640.10 Mainly Alpha › Orthogonal Bundle › Myeloperoxidase, subunit C › Haem peroxidase domain superfamily, animal type 0.56 48.0 2.97e-01 95.8% 77.0%
5bn3A04 1.10.1140.10 Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 0.55 40.0 3.59e-01 76.8% 92.1%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 41.0 3.58e-01 78.9% 83.8%
1ulyA02 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.54 38.0 3.80e-01 87.4% 69.3%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.54 49.0 3.75e-01 100.0% 60.6%
1a9xA04 1.10.1030.10 Mainly Alpha › Orthogonal Bundle › Carbamoyl Phosphate Synthetase; Chain A, domain 4 › Carbamoyl-phosphate synthetase, large subunit oligomerisation domain 0.54 45.0 3.92e-01 93.7% 70.0%
3ccyA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 35.0 3.02e-01 70.5% 53.7%
1t10A01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.51 39.0 2.65e-01 96.8% 21.4%
4im0A04 1.20.1270.420 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.50 44.0 3.30e-01 97.9% 74.8%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3324827 5076.2.1.0 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ 0.78 50.0 3.49e-01 94.7% 22.5%
4980771 1174.1.1.2 alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA 0.75 54.0 4.31e-01 75.8% 71.4%
3930918 5001.1.1.69 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srd 0.75 54.0 3.77e-01 76.8% 51.7%
3722843 1174.1.1.2 alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA 0.74 54.0 4.05e-01 75.8% 62.7%
4078984 1174.1.1.2 alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA 0.72 53.0 4.31e-01 76.8% 76.6%
3869130 604.12.1.72 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › OSTMP1 0.72 45.0 4.55e-01 90.5% 63.2%
3622690 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.71 51.0 5.22e-01 83.2% 77.8%
4883852 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.68 51.0 4.66e-01 80.0% 70.3%
3200574 601.1.2.81 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Serinc 0.68 44.0 4.08e-01 95.8% 51.7%
3702125 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.68 46.0 4.04e-01 100.0% 47.1%
4318541 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.67 46.0 4.49e-01 70.5% 84.8%
4848262 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.66 48.0 4.60e-01 98.9% 66.4%
2105845 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.65 49.0 4.51e-01 80.0% 70.2%
5061845 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.64 46.0 4.57e-01 87.4% 71.0%
3626569 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.64 53.0 4.50e-01 89.5% 83.2%
3785439 5069.1.1.4 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct 0.64 48.0 4.66e-01 82.1% 89.1%
3612403 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.64 50.0 4.36e-01 84.2% 74.5%
3582431 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.64 52.0 4.50e-01 89.5% 86.0%
5048512 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.63 41.0 4.19e-01 97.9% 66.3%
5074033 2004.1.3.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.63 45.0 3.53e-01 94.7% 35.7%
3647788 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.63 44.0 4.50e-01 80.0% 73.7%
3678972 604.6.1.38 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › CASP_dom 0.61 44.0 4.28e-01 100.0% 67.0%
3228316 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.60 48.0 4.13e-01 90.5% 85.5%
3805389 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.59 45.0 4.10e-01 80.0% 76.8%
3483038 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.59 49.0 4.50e-01 91.6% 95.2%
4927596 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.58 50.0 4.54e-01 95.8% 98.5%
4032834 604.5.1.69 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PF28025 0.56 49.0 4.16e-01 100.0% 78.2%
3500243 1008.1.1.74 alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › CC_Cfap43 0.55 47.0 4.12e-01 100.0% 62.9%
3263150 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.54 47.0 3.46e-01 97.9% 57.0%
3171352 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.54 37.0 3.16e-01 100.0% 42.5%
4097040 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.53 40.0 3.95e-01 80.0% 98.0%
3688803 105.1.1.0 alpha duplicates or obligate multimers › HLH-like › HLH, helix-loop-helix DNA-binding domain › HLH, helix-loop-helix DNA-binding domain 0.53 33.0 3.43e-01 88.4% 66.7%
3930751 509.1.1.1 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH 0.53 39.0 3.91e-01 92.6% 78.9%
3408650 1075.5.1.5 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Rft-1 0.52 44.0 3.24e-01 92.6% 65.8%
3936021 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.51 46.0 3.55e-01 100.0% 55.7%
3254418 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.51 41.0 2.62e-01 88.4% 27.3%
D5 medium residues 321-339_352-414
PDB
Domain cluster: representative
CATH (60)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1chuA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.75 55.0 5.38e-01 76.8% 85.2%
4q20A01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.74 43.0 4.39e-01 100.0% 58.5%
4lixA03 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.74 64.0 4.52e-01 93.9% 36.0%
7odyC01 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.72 48.0 4.67e-01 95.1% 62.0%
4flbA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.70 51.0 4.34e-01 76.8% 48.9%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.70 50.0 4.66e-01 76.8% 68.9%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 50.0 5.63e-01 76.8% 100.0%
3cqcB01 1.20.58.1380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 49.0 4.80e-01 76.8% 68.9%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.68 49.0 3.84e-01 76.8% 89.5%
6tblB01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.68 47.0 4.31e-01 76.8% 54.1%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.68 49.0 4.53e-01 76.8% 84.9%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.68 49.0 3.65e-01 76.8% 52.2%
3ajfA00 1.20.1440.190 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tenuivirus movement protein 0.68 56.0 5.39e-01 89.0% 92.4%
3zheA02 1.25.40.760 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 49.0 3.63e-01 76.8% 31.9%
2lseA00 1.20.120.1360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.67 58.0 5.48e-01 97.6% 80.2%
4gpkB01 1.25.40.1000 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 50.0 4.75e-01 80.5% 91.9%
2juaA00 1.20.1480.30 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein 0.66 56.0 5.24e-01 95.1% 95.1%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.66 53.0 5.01e-01 86.6% 88.9%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.66 49.0 4.88e-01 76.8% 90.4%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 47.0 4.14e-01 76.8% 77.0%
4akgA04 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.65 52.0 4.13e-01 84.1% 60.9%
4gmnA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.65 47.0 2.85e-01 76.8% 11.4%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 47.0 4.41e-01 76.8% 95.0%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 58.0 4.65e-01 98.8% 66.7%
2uvaG01 1.20.1050.120 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 58.0 4.81e-01 96.3% 61.0%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 45.0 3.57e-01 73.2% 44.4%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 45.0 3.46e-01 75.6% 84.5%
4jgwA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.64 45.0 3.68e-01 74.4% 42.3%
2oc5A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 55.0 4.03e-01 96.3% 53.5%
3qbrX00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.63 52.0 4.17e-01 90.2% 91.3%
1bgcA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.63 57.0 4.52e-01 98.8% 69.6%
3p9dE01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.62 55.0 3.83e-01 98.8% 58.1%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 45.0 4.01e-01 76.8% 59.0%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.62 46.0 4.57e-01 79.3% 96.6%
3f7cA00 1.20.1590.10 Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like 0.61 52.0 4.05e-01 100.0% 78.9%
1ho8A02 1.25.40.150 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › V-type ATPase, subunit H, C-terminal domain 0.61 45.0 4.09e-01 79.3% 94.6%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 44.0 3.81e-01 76.8% 66.2%
1su0B00 3.90.1010.10 Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › 0.60 52.0 4.44e-01 97.6% 66.2%
5hyhA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.60 51.0 3.57e-01 97.6% 45.3%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.59 50.0 5.00e-01 95.1% 95.3%
1iygA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 51.0 4.29e-01 92.7% 90.2%
2hroA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.59 52.0 4.54e-01 100.0% 89.8%
1eteA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.59 54.0 4.54e-01 100.0% 90.3%
2yw6B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 52.0 4.26e-01 98.8% 65.3%
1lwbA00 1.20.90.10 Mainly Alpha › Up-down Bundle › Phospholipase A2 › Phospholipase A2 domain 0.57 47.0 4.21e-01 93.9% 63.9%
6ks6Z01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.56 49.0 3.47e-01 98.8% 56.9%
1gcvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 44.0 3.80e-01 87.8% 99.3%
1k8kG00 1.25.40.190 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Actin-related protein 2/3 complex subunit 5 0.56 46.0 3.87e-01 89.0% 64.0%
2oqhA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.56 49.0 4.41e-01 98.8% 86.0%
4fxdA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.55 49.0 3.85e-01 92.7% 78.4%
3gyuA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.55 49.0 3.48e-01 97.6% 76.9%
3on3B00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.54 43.0 3.45e-01 98.8% 41.7%
8jx6A02 2.30.30.780 Mainly Beta › Roll › SH3 type barrels. › 0.54 46.0 4.26e-01 91.5% 89.3%
7xcnM01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.54 37.0 3.79e-01 70.7% 87.2%
1rvkA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.53 46.0 4.13e-01 97.6% 95.7%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 36.0 3.66e-01 100.0% 73.5%
4nufA02 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.51 41.0 3.29e-01 89.0% 58.1%
1f5oA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 42.0 3.59e-01 96.3% 90.6%
3bulA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.50 39.0 3.83e-01 84.1% 94.3%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.50 40.0 2.87e-01 100.0% 30.1%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3731974 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.85 49.0 4.37e-01 100.0% 43.6%
4630964 610.1.1.1 alpha arrays › ERP29 C domain-like › ERP29 C domain-like › ERP29 C domain-like › ERp29 0.82 57.0 5.96e-01 81.7% 78.7%
3262256 610.1.1.1 alpha arrays › ERP29 C domain-like › ERP29 C domain-like › ERP29 C domain-like › ERp29 0.81 56.0 5.30e-01 81.7% 61.1%
4236831 604.6.1.50 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF2524 0.80 57.0 5.77e-01 73.2% 97.5%
3228159 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.79 55.0 4.46e-01 73.2% 63.3%
3528346 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.78 56.0 4.37e-01 74.4% 58.2%
3919843 604.1.1.124 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 0.78 57.0 4.83e-01 76.8% 84.6%
3938720 4156.1.1.0 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like 0.78 57.0 4.46e-01 76.8% 88.5%
5039404 604.2.1.0 alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 0.77 54.0 5.69e-01 73.2% 94.7%
5048041 610.2.1.0 alpha arrays › ERP29 C domain-like › Helical domain of Sec23/24 › Helical domain of Sec23/24 0.75 52.0 4.98e-01 72.0% 70.5%
3600701 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.75 57.0 3.95e-01 80.5% 75.2%
1676534 633.26.1.1 alpha bundles › Bromodomain-like › SidC lipid-binding domain › SidC lipid-binding domain › SidC_lipid-bd 0.73 64.0 5.51e-01 97.6% 85.6%
3974692 1026.1.1.0 alpha bundles › Rev protein › Rev protein › Rev protein 0.73 65.0 5.22e-01 98.8% 89.4%
3973500 601.1.2.144 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HBM 0.73 65.0 5.77e-01 97.6% 94.8%
3940791 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 51.0 4.76e-01 72.0% 94.0%
4850960 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.73 56.0 4.51e-01 81.7% 48.1%
3968401 109.4.1.86 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF924 0.73 58.0 4.38e-01 85.4% 77.4%
3184336 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.73 63.0 5.10e-01 95.1% 85.8%
3991109 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.72 63.0 5.34e-01 98.8% 93.6%
3908662 109.4.1.1 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 0.72 55.0 3.88e-01 80.5% 78.3%
3707921 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.72 62.0 5.62e-01 95.1% 90.9%
5079853 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.71 63.0 5.40e-01 98.8% 98.5%
3499296 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.71 62.0 4.91e-01 97.6% 87.6%
3252898 109.4.1.1 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 0.70 56.0 3.94e-01 84.1% 71.1%
3602825 633.12.1.0 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like 0.70 63.0 5.42e-01 100.0% 69.2%
5019543 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.70 52.0 4.82e-01 76.8% 74.0%
3257347 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 51.0 2.93e-01 76.8% 8.1%
3744228 109.4.1.322 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nse5 0.68 51.0 3.39e-01 80.5% 37.6%
5033625 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.68 62.0 4.34e-01 100.0% 36.0%
3431415 6155.1.1.6 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921 0.68 50.0 4.95e-01 76.8% 87.1%
3405478 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.67 59.0 5.03e-01 98.8% 94.8%
3798925 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.67 49.0 4.93e-01 76.8% 90.6%
4352755 109.4.1.630 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CNOT1_TTP_bind,CNOT1_HEAT 0.67 49.0 2.92e-01 76.8% 13.0%
3489166 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 52.0 3.38e-01 80.5% 43.4%
1713334 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.67 49.0 4.35e-01 76.8% 65.8%
3365571 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.67 49.0 4.51e-01 76.8% 73.3%
4929003 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.67 49.0 4.76e-01 76.8% 83.3%
3348578 109.4.1.1 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 0.67 49.0 3.54e-01 80.5% 74.9%
5074861 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.66 59.0 3.87e-01 98.8% 28.1%
3844702 109.4.1.630 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CNOT1_TTP_bind,CNOT1_HEAT 0.66 48.0 3.19e-01 76.8% 23.0%
3549956 109.4.1.1655 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N, HEAT, HEAT_2 0.66 49.0 3.35e-01 80.5% 29.5%
1411677 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.66 49.0 4.88e-01 76.8% 90.4%
3276327 593.1.1.0 alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like 0.65 59.0 4.35e-01 98.8% 58.3%
3602354 1030.1.1.1 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Csm2_III-A 0.65 56.0 4.93e-01 95.1% 74.2%
3394451 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.65 47.0 4.09e-01 76.8% 59.2%
4043634 109.4.1.441 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TFCD_C 0.65 51.0 3.12e-01 84.1% 33.8%
3256198 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.64 47.0 3.99e-01 76.8% 57.7%
3794786 630.1.1.0 a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain 0.63 53.0 4.56e-01 87.8% 100.0%
3426697 371.1.1.7 few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › zf-RVT 0.63 51.0 4.07e-01 87.8% 60.6%
4959463 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.63 45.0 4.56e-01 75.6% 91.3%
4934465 593.1.1.1 alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 0.62 55.0 3.87e-01 98.8% 57.7%
5029393 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.62 49.0 4.74e-01 82.9% 82.0%
3616226 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.61 49.0 4.26e-01 84.1% 61.7%
3677410 371.1.1.7 few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › zf-RVT 0.61 51.0 4.10e-01 91.5% 60.0%
3216480 5001.1.1.84 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz 0.61 49.0 3.30e-01 86.6% 63.9%
5058589 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 42.0 3.56e-01 76.8% 61.3%
3771177 532.2.1.0 alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains 0.59 40.0 4.11e-01 72.0% 78.8%
3230343 109.54.1.1 alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 0.57 49.0 4.19e-01 92.7% 64.0%
3593881 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 48.0 3.34e-01 93.9% 36.2%
4985462 192.2.1.89 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › DUF7121 0.54 47.0 3.44e-01 100.0% 42.5%
3552989 604.8.1.1 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Smac_DIABLO 0.53 38.0 2.98e-01 75.6% 66.8%
5013043 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 43.0 3.17e-01 89.0% 39.6%
2966548 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.52 38.0 3.00e-01 79.3% 40.4%
3884160 196.1.1.2 alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS-like 0.52 45.0 3.37e-01 98.8% 88.1%