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MT664721.1__QMP81460.1__X__00003
Bact-VirMT664721.1__QMP81460.1__X__00003
Identity
- Accession:
- MT664721 ↗
- Kingdom:
- phage
Quality
84.8
mean pLDDT
Cluster
View cluster (3 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 59-157
Domain cluster:
representative
CATH (70)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.79 | 69.0 | 7.11e-01 | 92.9% | 100.0% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.77 | 64.0 | 6.34e-01 | 89.9% | 100.0% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.76 | 63.0 | 6.16e-01 | 89.9% | 100.0% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.75 | 62.0 | 6.02e-01 | 88.9% | 100.0% |
| 4mrsA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.75 | 59.0 | 4.06e-01 | 84.8% | 43.3% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.75 | 62.0 | 6.03e-01 | 88.9% | 100.0% |
| 2o5iN07 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.74 | 56.0 | 5.26e-01 | 78.8% | 93.1% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.72 | 61.0 | 5.39e-01 | 90.9% | 68.1% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.69 | 58.0 | 4.64e-01 | 89.9% | 98.4% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 52.0 | 4.51e-01 | 78.8% | 91.9% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.68 | 57.0 | 4.61e-01 | 89.9% | 100.0% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.67 | 50.0 | 5.51e-01 | 86.9% | 100.0% |
| 7e84A03 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 47.0 | 4.41e-01 | 99.0% | 59.3% |
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.66 | 52.0 | 3.50e-01 | 93.9% | 21.0% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.65 | 46.0 | 4.47e-01 | 71.7% | 83.6% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 43.0 | 3.86e-01 | 75.8% | 49.6% |
| 1u00A02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.65 | 42.0 | 4.33e-01 | 73.7% | 67.7% |
| 1urvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.64 | 53.0 | 4.57e-01 | 88.9% | 95.5% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 55.0 | 4.53e-01 | 93.9% | 59.8% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 40.0 | 4.45e-01 | 73.7% | 78.8% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.64 | 57.0 | 4.87e-01 | 97.0% | 65.8% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 46.0 | 3.29e-01 | 73.7% | 80.9% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.64 | 50.0 | 4.42e-01 | 86.9% | 57.6% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.64 | 48.0 | 3.79e-01 | 80.8% | 89.2% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 45.0 | 3.86e-01 | 73.7% | 88.6% |
| 4gc0A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.63 | 54.0 | 4.19e-01 | 96.0% | 79.2% |
| 8ex5A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.63 | 50.0 | 4.07e-01 | 86.9% | 85.9% |
| 3iq1B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 46.0 | 3.98e-01 | 78.8% | 89.9% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 47.0 | 4.56e-01 | 77.8% | 77.6% |
| 1jvmB00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 43.0 | 4.38e-01 | 99.0% | 72.0% |
| 2qqyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 46.0 | 4.17e-01 | 78.8% | 93.5% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.61 | 53.0 | 5.24e-01 | 97.0% | 100.0% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 55.0 | 4.59e-01 | 100.0% | 82.7% |
| 1aj3A00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 46.0 | 4.70e-01 | 81.8% | 98.0% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 45.0 | 4.30e-01 | 80.8% | 78.7% |
| 4dxwA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 43.0 | 4.14e-01 | 94.9% | 65.2% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.60 | 55.0 | 5.22e-01 | 100.0% | 98.3% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.60 | 47.0 | 3.81e-01 | 84.8% | 79.1% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.60 | 48.0 | 5.02e-01 | 87.9% | 96.7% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.60 | 44.0 | 4.63e-01 | 77.8% | 93.1% |
| 1umnG00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 44.0 | 3.67e-01 | 75.8% | 73.3% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.60 | 46.0 | 4.71e-01 | 85.9% | 97.9% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.59 | 48.0 | 4.58e-01 | 92.9% | 75.0% |
| 2ibdA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 51.0 | 4.50e-01 | 97.0% | 64.6% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.58 | 41.0 | 3.50e-01 | 73.7% | 46.0% |
| 4ivfA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 45.0 | 4.32e-01 | 83.8% | 82.8% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.58 | 49.0 | 4.39e-01 | 90.9% | 82.5% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 47.0 | 4.14e-01 | 86.9% | 82.5% |
| 1kn1B00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.57 | 44.0 | 3.74e-01 | 80.8% | 79.5% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.57 | 45.0 | 4.76e-01 | 85.9% | 97.7% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.57 | 51.0 | 4.48e-01 | 98.0% | 69.9% |
| 3qc1A01 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.56 | 44.0 | 3.88e-01 | 84.8% | 94.7% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.56 | 41.0 | 4.03e-01 | 79.8% | 70.5% |
| 1udyA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.56 | 41.0 | 3.89e-01 | 77.8% | 65.0% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.56 | 45.0 | 4.69e-01 | 85.9% | 95.5% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.56 | 45.0 | 3.70e-01 | 89.9% | 66.7% |
| 3vkgA15 | 1.10.8.1220 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.55 | 41.0 | 4.18e-01 | 81.8% | 80.9% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.55 | 48.0 | 3.82e-01 | 97.0% | 51.7% |
| 4hz4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 42.0 | 4.11e-01 | 82.8% | 76.8% |
| 7lb8B01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.55 | 44.0 | 3.09e-01 | 86.9% | 85.8% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 46.0 | 3.82e-01 | 90.9% | 53.5% |
| 5xtck00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 39.0 | 3.96e-01 | 80.8% | 77.3% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.54 | 45.0 | 4.27e-01 | 90.9% | 79.7% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 44.0 | 4.38e-01 | 88.9% | 100.0% |
| 3a7mA01 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.54 | 45.0 | 4.39e-01 | 91.9% | 82.7% |
| 3cbuA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 44.0 | 4.02e-01 | 89.9% | 70.9% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.54 | 40.0 | 4.08e-01 | 86.9% | 80.0% |
| 1jgcA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 46.0 | 3.98e-01 | 98.0% | 98.8% |
| 3lxzB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.53 | 42.0 | 3.84e-01 | 87.9% | 66.7% |
| 6a3kA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.53 | 42.0 | 3.90e-01 | 85.9% | 88.4% |
ECOD (72)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3539016 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.90 | 83.0 | 8.15e-01 | 97.0% | 96.2% |
| 4653062 | 604.4.1.0 ↗ | alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP | 0.90 | 85.0 | 8.21e-01 | 100.0% | 94.5% |
| 3722363 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.81 | 70.0 | 5.91e-01 | 92.9% | 78.1% |
| 5023246 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.81 | 70.0 | 5.70e-01 | 91.9% | 59.5% |
| 4381446 | 3896.1.1.0 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase | 0.80 | 68.0 | 5.02e-01 | 90.9% | 42.1% |
| 4323122 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.78 | 71.0 | 4.57e-01 | 99.0% | 23.2% |
| 5047547 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.77 | 68.0 | 6.46e-01 | 96.0% | 91.3% |
| 4945061 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.76 | 63.0 | 4.97e-01 | 88.9% | 52.5% |
| 4267909 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.74 | 56.0 | 4.43e-01 | 97.0% | 40.5% |
| 4036645 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.73 | 54.0 | 4.31e-01 | 100.0% | 39.5% |
| 5083369 | 604.4.1.0 ↗ | alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP | 0.73 | 59.0 | 6.12e-01 | 86.9% | 97.8% |
| 3472115 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.72 | 60.0 | 5.59e-01 | 90.9% | 100.0% |
| 3391570 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.72 | 65.0 | 5.11e-01 | 100.0% | 50.7% |
| 4018207 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.72 | 65.0 | 5.47e-01 | 100.0% | 89.1% |
| 3276887 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.71 | 51.0 | 4.88e-01 | 84.8% | 64.3% |
| 3481326 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.70 | 57.0 | 4.71e-01 | 88.9% | 98.3% |
| 3515847 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.69 | 57.0 | 5.85e-01 | 87.9% | 92.6% |
| 4016236 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.69 | 59.0 | 5.81e-01 | 92.9% | 100.0% |
| 4010684 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.69 | 60.0 | 3.94e-01 | 92.9% | 40.8% |
| 4528425 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.69 | 56.0 | 5.60e-01 | 87.9% | 91.0% |
| 3262258 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.69 | 59.0 | 4.92e-01 | 93.9% | 99.4% |
| 3718013 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.68 | 58.0 | 5.94e-01 | 91.9% | 100.0% |
| 3459347 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.67 | 56.0 | 4.62e-01 | 91.9% | 99.4% |
| 3393689 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.66 | 55.0 | 4.51e-01 | 89.9% | 97.2% |
| 5067554 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.66 | 54.0 | 4.39e-01 | 87.9% | 84.3% |
| 3385581 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.66 | 54.0 | 4.39e-01 | 87.9% | 88.6% |
| 4985507 | 604.10.1.0 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac | 0.65 | 49.0 | 5.13e-01 | 80.8% | 92.2% |
| 4956683 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 56.0 | 5.63e-01 | 96.0% | 100.0% |
| 3284641 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.65 | 53.0 | 4.32e-01 | 88.9% | 82.1% |
| 3743731 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.65 | 61.0 | 4.62e-01 | 100.0% | 63.3% |
| 4192694 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.64 | 56.0 | 4.30e-01 | 97.0% | 74.3% |
| 3583102 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 46.0 | 5.10e-01 | 80.8% | 93.8% |
| 3914646 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 54.0 | 4.20e-01 | 93.9% | 72.3% |
| 4015069 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.63 | 54.0 | 4.17e-01 | 94.9% | 79.6% |
| 4018363 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.63 | 52.0 | 4.19e-01 | 89.9% | 85.1% |
| 3202274 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.63 | 54.0 | 4.21e-01 | 93.9% | 81.4% |
| 5076502 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 53.0 | 4.19e-01 | 93.9% | 78.1% |
| 3628101 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.63 | 53.0 | 4.90e-01 | 96.0% | 72.0% |
| 4948140 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 50.0 | 4.05e-01 | 85.9% | 81.1% |
| 3506950 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.63 | 51.0 | 5.37e-01 | 87.9% | 100.0% |
| 4600613 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.63 | 50.0 | 4.57e-01 | 85.9% | 89.2% |
| 3977407 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 53.0 | 4.16e-01 | 91.9% | 77.6% |
| 3971653 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 50.0 | 4.13e-01 | 88.9% | 88.4% |
| 3204078 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 52.0 | 3.98e-01 | 93.9% | 80.0% |
| 3998127 | 5050.1.1.5 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Folate_carrier | 0.61 | 50.0 | 3.82e-01 | 87.9% | 70.0% |
| 3539317 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 54.0 | 4.11e-01 | 98.0% | 70.2% |
| 3183504 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.61 | 52.0 | 3.98e-01 | 92.9% | 77.3% |
| 3597956 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 47.0 | 5.03e-01 | 81.8% | 96.5% |
| 3744639 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 52.0 | 4.04e-01 | 97.0% | 82.1% |
| 4289864 | 601.25.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain | 0.60 | 46.0 | 4.04e-01 | 81.8% | 71.3% |
| 4995297 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.60 | 48.0 | 4.63e-01 | 87.9% | 82.6% |
| 4881515 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.59 | 48.0 | 4.46e-01 | 88.9% | 86.5% |
| 5027021 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.58 | 52.0 | 4.94e-01 | 99.0% | 94.8% |
| 3786750 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.58 | 48.0 | 4.80e-01 | 92.9% | 92.3% |
| 3341807 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.58 | 48.0 | 4.69e-01 | 91.9% | 83.6% |
| 4095048 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.58 | 43.0 | 4.05e-01 | 77.8% | 67.5% |
| 4933622 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.58 | 46.0 | 4.66e-01 | 89.9% | 99.0% |
| 3974221 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.58 | 51.0 | 4.64e-01 | 97.0% | 77.7% |
| 3874768 | 192.29.1.127 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › ApoL | 0.58 | 45.0 | 4.26e-01 | 81.8% | 73.9% |
| 3409714 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.57 | 49.0 | 4.93e-01 | 98.0% | 97.0% |
| 3948656 | 601.4.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › NIT | 0.57 | 49.0 | 4.26e-01 | 93.9% | 69.7% |
| 3828970 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.57 | 49.0 | 4.99e-01 | 93.9% | 100.0% |
| 3619724 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.57 | 44.0 | 4.47e-01 | 82.8% | 88.0% |
| 3579241 | 192.29.1.50 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PTPLA | 0.57 | 42.0 | 4.02e-01 | 77.8% | 93.0% |
| 3262020 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 44.0 | 3.50e-01 | 84.8% | 54.6% |
| 3605285 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.55 | 47.0 | 4.26e-01 | 99.0% | 68.3% |
| 157647 | 133.2.1.1 ↗ | alpha bundles › DH domain-like › Methenyltetrahydrofolate cyclohydrolase-like › Methenyltetrahydrofolate cyclohydrolase-like › FTCD_C | 0.54 | 47.0 | 3.72e-01 | 97.0% | 49.3% |
| 4934784 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.53 | 39.0 | 4.22e-01 | 82.8% | 91.8% |
| 3407718 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.52 | 36.0 | 3.41e-01 | 72.7% | 56.8% |
| 3863308 | 109.4.1.869 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INT1_R3 | 0.52 | 36.0 | 2.88e-01 | 71.7% | 52.7% |
| 3681372 | 109.4.1.1555 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_19 | 0.51 | 45.0 | 3.23e-01 | 93.9% | 36.7% |
| 3880276 | 174.1.1.34 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › FAM70 | 0.51 | 42.0 | 3.58e-01 | 97.0% | 69.7% |
D2
high
residues 604-672
Domain cluster:
representative
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ffkA02 | 3.55.40.20 | Alpha Beta › 3-Layer(bab) Sandwich › minor pseudopilin epsh fold › Iron/manganese superoxide dismutase, C-terminal domain | 0.63 | 44.0 | 3.69e-01 | 73.9% | 90.2% |
| 1vehA01 | 3.30.300.130 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Fe-S cluster assembly (FSCA) | 0.62 | 35.0 | 3.42e-01 | 87.0% | 48.0% |
| 3icaB00 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.62 | 43.0 | 3.15e-01 | 82.6% | 24.8% |
| 2hjjA00 | 3.30.160.130 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › ykff protein like domains | 0.61 | 36.0 | 3.71e-01 | 94.2% | 62.1% |
| 1nw1A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.61 | 51.0 | 4.59e-01 | 94.2% | 76.0% |
| 6j9eJ00 | 3.30.160.560 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.60 | 32.0 | 3.26e-01 | 98.6% | 51.5% |
| 2iafA00 | 3.30.1330.90 | Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › D-3-phosphoglycerate dehydrogenase; domain 3 | 0.59 | 46.0 | 3.77e-01 | 88.4% | 86.4% |
| 2oluA01 | 3.90.1310.20 | Alpha Beta › Alpha-Beta Complex › Penicillin-binding protein 2a (Domain 2) › | 0.58 | 49.0 | 4.47e-01 | 100.0% | 86.9% |
| 3i9v700 | 3.30.920.80 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › NADH-quinone oxidoreductase, subunit 15 | 0.58 | 45.0 | 3.72e-01 | 85.5% | 93.7% |
| 1khiA01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.57 | 38.0 | 3.75e-01 | 94.2% | 64.0% |
| 1w94A00 | 3.40.50.10480 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Brix domain | 0.57 | 43.0 | 3.34e-01 | 100.0% | 36.8% |
| 1maiA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.55 | 41.0 | 3.60e-01 | 85.5% | 81.5% |
| 6zepA01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.55 | 44.0 | 2.88e-01 | 89.9% | 77.8% |
| 3dcxA00 | 2.30.29.50 | Mainly Beta › Roll › PH-domain like › Bacterial Pleckstrin homology domain | 0.54 | 40.0 | 3.41e-01 | 78.3% | 62.4% |
| 3tdgA01 | 3.10.450.520 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 36.0 | 3.72e-01 | 81.2% | 72.7% |
| 2p25A01 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.54 | 34.0 | 2.94e-01 | 76.8% | 37.0% |
| 2ob9A00 | 3.30.2220.20 | Alpha Beta › 2-Layer Sandwich › rbstp2171 › Phage tail assembly chaperone gp13-like | 0.54 | 35.0 | 3.06e-01 | 91.3% | 43.0% |
| 3ghjA00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.54 | 33.0 | 2.82e-01 | 78.3% | 35.3% |
| 2k49A00 | 2.30.29.80 | Mainly Beta › Roll › PH-domain like › | 0.53 | 38.0 | 3.33e-01 | 79.7% | 54.2% |
| 1qypA00 | 2.20.25.10 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.53 | 34.0 | 3.70e-01 | 100.0% | 78.9% |
| 4r60A01 | 3.40.350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain | 0.53 | 43.0 | 3.31e-01 | 91.3% | 87.0% |
| 1b63A01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.52 | 42.0 | 3.07e-01 | 91.3% | 61.1% |
| 3x29A00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.52 | 43.0 | 3.21e-01 | 88.4% | 92.2% |
| 3brcA02 | 3.40.50.10150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › B12-dependent dehydatase associated subunit | 0.52 | 45.0 | 3.83e-01 | 100.0% | 87.5% |
| 1n0uA03 | 3.90.1430.10 | Alpha Beta › Alpha-Beta Complex › Yeast translation eEF2 (G' domain) › Yeast translation eEF2 (G' domain) | 0.52 | 37.0 | 3.22e-01 | 75.4% | 55.1% |
| 3ebrA00 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.52 | 36.0 | 2.74e-01 | 72.5% | 72.4% |
| 8adlB01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.52 | 43.0 | 2.89e-01 | 98.6% | 25.8% |
| 4hvtA01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 41.0 | 2.67e-01 | 87.0% | 67.3% |
| 3dbaA00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.52 | 41.0 | 3.10e-01 | 87.0% | 86.5% |
| 1t4lB00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.51 | 35.0 | 3.25e-01 | 71.0% | 65.6% |
| 1ewqA04 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.51 | 41.0 | 3.36e-01 | 89.9% | 51.5% |
| 2kgtA00 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.51 | 40.0 | 4.03e-01 | 100.0% | 84.7% |
| 8hmcA01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.51 | 44.0 | 2.88e-01 | 100.0% | 21.8% |
| 2fgzA01 | 2.60.40.1130 | Mainly Beta › Sandwich › Immunoglobulin-like › Rab geranylgeranyltransferase alpha-subunit, insert domain | 0.50 | 42.0 | 3.56e-01 | 92.8% | 84.3% |
| 5c71A02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.50 | 43.0 | 3.84e-01 | 94.2% | 85.4% |
| 2xepB01 | 3.10.450.280 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.50 | 41.0 | 3.66e-01 | 100.0% | 76.3% |
| 3a9gA00 | 2.120.10.30 | Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain | 0.50 | 42.0 | 2.79e-01 | 100.0% | 45.9% |
ECOD (48)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3993357 | 11.2.1.57 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PF28126 | 0.70 | 59.0 | 4.50e-01 | 91.3% | 71.0% |
| 3224716 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.70 | 48.0 | 4.13e-01 | 71.0% | 70.0% |
| 3242250 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.69 | 47.0 | 4.01e-01 | 71.0% | 69.3% |
| 3732571 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.67 | 40.0 | 4.24e-01 | 98.6% | 68.3% |
| 3743614 | 4.1.1.28 ↗ | beta barrels › SH3 › SH3 › SH3 › BPL_C | 0.65 | 37.0 | 3.97e-01 | 98.6% | 65.0% |
| 4008588 | 101.1.9.63 ↗ | alpha arrays › HTH › HTH › Putative DNA-binding domain › Bro-N | 0.64 | 45.0 | 3.86e-01 | 73.9% | 80.0% |
| 4945086 | 239.5.1.0 ↗ | beta barrels › Ribosomal protein L25-like › 40S ribosomal protein S3A N-terminal domain › 40S ribosomal protein S3A N-terminal domain | 0.63 | 37.0 | 3.70e-01 | 100.0% | 57.1% |
| 3242022 | 220.1.1.68 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_Tiam1 | 0.62 | 46.0 | 3.64e-01 | 79.7% | 41.4% |
| 3999277 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.62 | 44.0 | 3.86e-01 | 81.2% | 48.2% |
| 3997189 | 305.1.1.0 ↗ | a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase | 0.60 | 42.0 | 3.99e-01 | 79.7% | 61.2% |
| 4028739 | 316.1.1.30 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PAP_NTPase | 0.59 | 43.0 | 3.26e-01 | 81.2% | 64.2% |
| 3608673 | 109.4.1.194 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10 | 0.58 | 45.0 | 2.94e-01 | 92.8% | 17.4% |
| None | — | 0.56 | 42.0 | 3.16e-01 | 82.6% | 70.5% | |
| 3315951 | 220.1.1.86 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › ZGRF1-like_N | 0.56 | 39.0 | 3.75e-01 | 97.1% | 63.3% |
| 3833207 | 5.1.4.319 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR11_1st | 0.56 | 47.0 | 2.90e-01 | 100.0% | 29.1% |
| 1126976 | 223.3.1.3 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.56 | 39.0 | 3.88e-01 | 72.5% | 100.0% |
| 5008209 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.56 | 35.0 | 3.34e-01 | 98.6% | 55.0% |
| 3511988 | 243.6.1.4 ↗ | a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain › Pre-PUA | 0.55 | 46.0 | 4.30e-01 | 97.1% | 73.3% |
| 3286426 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.55 | 40.0 | 3.97e-01 | 92.8% | 73.3% |
| None | — | 0.55 | 43.0 | 2.83e-01 | 94.2% | 18.5% | |
| 3681726 | 5.1.3.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed | 0.55 | 47.0 | 3.07e-01 | 100.0% | 31.5% |
| 3798149 | 601.23.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III | 0.55 | 45.0 | 2.97e-01 | 91.3% | 26.4% |
| 3187098 | 7579.1.1.36 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_3 | 0.54 | 45.0 | 2.94e-01 | 97.1% | 70.8% |
| 3789210 | 601.23.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_III | 0.54 | 44.0 | 2.89e-01 | 91.3% | 24.7% |
| 4031851 | 246.2.1.9 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos_2 | 0.54 | 47.0 | 3.56e-01 | 97.1% | 97.6% |
| 3968506 | 3859.1.1.0 ↗ | alpha arrays › uncharacterized protein BT_1490 C-terminal domain › uncharacterized protein BT_1490 C-terminal domain › uncharacterized protein BT_1490 C-terminal domain | 0.54 | 45.0 | 3.97e-01 | 92.8% | 76.2% |
| 5007759 | 213.1.1.0 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) | 0.54 | 39.0 | 3.40e-01 | 97.1% | 48.2% |
| 3472236 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.53 | 42.0 | 3.00e-01 | 88.4% | 56.9% |
| 4013714 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.53 | 34.0 | 3.92e-01 | 100.0% | 95.8% |
| 3817060 | 109.4.1.1794 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Beta-prop_ELP1_1st, Beta-prop_ELP1_2nd | 0.53 | 45.0 | 2.76e-01 | 100.0% | 68.4% |
| 1513169 | 6043.1.1.2 ↗ | a+b two layers › yfeY-like › yfeY-like › yfeY-like › DUF4309 | 0.53 | 30.0 | 2.89e-01 | 97.1% | 46.9% |
| 3973606 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.53 | 35.0 | 3.72e-01 | 81.2% | 85.5% |
| 3549359 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.53 | 42.0 | 3.00e-01 | 91.3% | 57.0% |
| 4239277 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.52 | 39.0 | 3.42e-01 | 78.3% | 64.0% |
| 4647466 | 601.23.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III | 0.52 | 43.0 | 2.82e-01 | 91.3% | 23.8% |
| 3841889 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.52 | 41.0 | 3.01e-01 | 88.4% | 61.0% |
| 5069695 | 330.2.1.5 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › PF29181 | 0.52 | 43.0 | 3.84e-01 | 100.0% | 72.5% |
| 3177460 | 3270.1.1.0 ↗ | a+b two layers › a+b domain in heme oxygenase › a+b domain in heme oxygenase › a+b domain in heme oxygenase | 0.52 | 40.0 | 3.69e-01 | 92.8% | 64.0% |
| 3799509 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.52 | 39.0 | 2.87e-01 | 84.1% | 58.6% |
| 5080980 | 330.2.1.1 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › Ribosomal_S30AE | 0.51 | 42.0 | 3.78e-01 | 100.0% | 71.8% |
| 3167935 | 4045.1.1.1 ↗ | a+b two layers › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › barrel domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › Aminotran_4 | 0.51 | 43.0 | 3.40e-01 | 94.2% | 85.2% |
| 3180372 | 7579.1.1.36 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_3 | 0.51 | 43.0 | 2.81e-01 | 94.2% | 85.1% |
| 3285626 | 4090.1.1.0 ↗ | a+b two layers › BH3703-like › BH3703-like › BH3703-like | 0.51 | 39.0 | 3.04e-01 | 82.6% | 71.0% |
| 3596467 | 243.6.1.0 ↗ | a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain | 0.50 | 43.0 | 3.29e-01 | 98.6% | 41.7% |
| 4273009 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.50 | 40.0 | 2.98e-01 | 88.4% | 64.7% |
| 1203219 | 228.1.1.1 ↗ | a+b three layers › Fe,Mn superoxide dismutase (SOD)-C › Fe,Mn superoxide dismutase (SOD)-C › Fe,Mn superoxide dismutase (SOD)-C › Sod_Fe_C | 0.50 | 39.0 | 3.33e-01 | 97.1% | 50.0% |
| 3682622 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 42.0 | 2.56e-01 | 95.7% | 16.7% |
| 3426091 | 207.1.1.77 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FBD | 0.50 | 39.0 | 2.71e-01 | 85.5% | 60.0% |
D3
medium
residues 158-220
Domain cluster:
representative
CATH (40)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2wdqD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.88 | 66.0 | 5.46e-01 | 79.4% | 49.5% |
| 3u66A00 | 1.25.40.590 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU | 0.78 | 61.0 | 4.45e-01 | 85.7% | 40.5% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.77 | 69.0 | 5.76e-01 | 100.0% | 95.4% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.77 | 61.0 | 5.21e-01 | 85.7% | 64.6% |
| 3ztaA00 | 1.10.490.130 | Mainly Alpha › Orthogonal Bundle › Globin-like › | 0.75 | 68.0 | 5.21e-01 | 100.0% | 89.9% |
| 1a52A00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.74 | 65.0 | 4.40e-01 | 100.0% | 38.5% |
| 1vkeB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.73 | 60.0 | 5.11e-01 | 90.5% | 63.4% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.72 | 55.0 | 3.34e-01 | 82.5% | 24.3% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.71 | 60.0 | 5.17e-01 | 100.0% | 94.5% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.71 | 49.0 | 5.03e-01 | 81.0% | 76.3% |
| 4nbqB02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.70 | 61.0 | 5.64e-01 | 100.0% | 91.5% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.69 | 54.0 | 4.13e-01 | 87.3% | 36.7% |
| 1r1dA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.69 | 54.0 | 3.57e-01 | 84.1% | 45.5% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 49.0 | 5.08e-01 | 84.1% | 80.0% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 52.0 | 4.96e-01 | 82.5% | 88.0% |
| 3rauA00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.68 | 61.0 | 3.77e-01 | 100.0% | 26.3% |
| 6n2nA01 | 3.40.920.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | 0.68 | 49.0 | 3.63e-01 | 79.4% | 93.8% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.67 | 52.0 | 5.22e-01 | 84.1% | 81.2% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 56.0 | 5.27e-01 | 90.5% | 76.6% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 60.0 | 4.83e-01 | 100.0% | 85.2% |
| 2yw6B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 52.0 | 3.99e-01 | 87.3% | 73.3% |
| 2clbA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 52.0 | 3.90e-01 | 87.3% | 71.1% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.65 | 52.0 | 5.01e-01 | 85.7% | 77.5% |
| 2yjkC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 52.0 | 3.84e-01 | 85.7% | 35.0% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.64 | 50.0 | 4.62e-01 | 87.3% | 67.1% |
| 2nn4A00 | 1.10.287.760 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like | 0.64 | 47.0 | 4.76e-01 | 77.8% | 90.3% |
| 2e9xB02 | 1.20.58.1020 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 59.0 | 4.82e-01 | 100.0% | 66.1% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 50.0 | 4.99e-01 | 92.1% | 81.5% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.64 | 53.0 | 4.74e-01 | 90.5% | 93.0% |
| 1ykhA00 | 6.10.140.200 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 53.0 | 4.57e-01 | 90.5% | 61.1% |
| 2ynqB00 | 1.25.40.680 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain | 0.63 | 56.0 | 4.23e-01 | 100.0% | 43.7% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 55.0 | 4.12e-01 | 98.4% | 55.2% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 53.0 | 4.98e-01 | 96.8% | 77.6% |
| 3wozB00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.61 | 46.0 | 3.10e-01 | 81.0% | 22.7% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 55.0 | 5.00e-01 | 100.0% | 90.5% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.60 | 48.0 | 4.51e-01 | 90.5% | 87.3% |
| 3fghA00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.57 | 44.0 | 4.33e-01 | 84.1% | 92.5% |
| 1np7A02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 43.0 | 3.58e-01 | 87.3% | 64.7% |
| 2jgdB02 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.52 | 44.0 | 2.83e-01 | 100.0% | 57.6% |
| 2zfuA01 | 1.10.10.2150 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal RNA-processing protein 8, N-terminal domain | 0.51 | 35.0 | 3.86e-01 | 87.3% | 88.2% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4646569 | 4994.1.1.1 ↗ | alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 | 0.88 | 81.0 | 6.97e-01 | 100.0% | 88.4% |
| 3428374 | 109.7.1.25 ↗ | alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E › PPR | 0.84 | 78.0 | 6.24e-01 | 100.0% | 54.8% |
| 4346136 | 605.1.1.108 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › GrpE | 0.81 | 59.0 | 5.90e-01 | 84.1% | 75.4% |
| 3648733 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.80 | 71.0 | 4.90e-01 | 100.0% | 93.3% |
| 4362035 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.77 | 69.0 | 4.90e-01 | 100.0% | 95.7% |
| 5044421 | 592.2.1.0 ↗ | alpha arrays › PWI domain-like › YugE-like › YugE-like | 0.77 | 57.0 | 5.29e-01 | 79.4% | 85.0% |
| 3200626 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.76 | 67.0 | 4.69e-01 | 98.4% | 93.5% |
| 4287075 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.74 | 61.0 | 5.41e-01 | 90.5% | 77.8% |
| 4457135 | 1197.1.1.1 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf | 0.74 | 57.0 | 3.82e-01 | 82.5% | 34.3% |
| 4120236 | 192.29.1.236 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › AKAP95 | 0.74 | 60.0 | 5.79e-01 | 88.9% | 90.0% |
| 3486312 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.73 | 59.0 | 4.72e-01 | 90.5% | 46.2% |
| 4463205 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.71 | 56.0 | 3.33e-01 | 85.7% | 11.7% |
| 4258322 | 5086.1.1.189 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CzcB | 0.70 | 54.0 | 5.22e-01 | 90.5% | 72.9% |
| 2055367 | 650.1.1.3 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › HsbA | 0.70 | 53.0 | 5.13e-01 | 87.3% | 71.4% |
| None | — | 0.70 | 60.0 | 3.83e-01 | 98.4% | 94.1% | |
| 3476064 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.69 | 56.0 | 4.50e-01 | 88.9% | 45.8% |
| 3564106 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.69 | 61.0 | 5.13e-01 | 98.4% | 93.3% |
| 2391543 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.69 | 60.0 | 4.27e-01 | 100.0% | 89.8% |
| 3387986 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.69 | 57.0 | 3.87e-01 | 95.2% | 40.0% |
| 3229748 | 1134.1.1.9 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › RSLD_CPSF6 | 0.68 | 58.0 | 5.32e-01 | 96.8% | 80.0% |
| 3909017 | 192.5.1.1 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 | 0.68 | 58.0 | 5.04e-01 | 90.5% | 68.9% |
| 4106151 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.68 | 57.0 | 5.25e-01 | 96.8% | 82.4% |
| 4278607 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.67 | 58.0 | 3.24e-01 | 100.0% | 8.1% |
| 3974231 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.67 | 53.0 | 5.18e-01 | 85.7% | 81.4% |
| 3464751 | 109.4.1.1274 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, PPR_long | 0.67 | 50.0 | 3.39e-01 | 81.0% | 22.2% |
| 4056285 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.67 | 58.0 | 5.11e-01 | 100.0% | 70.5% |
| 5011187 | 4163.1.1.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 | 0.66 | 58.0 | 4.74e-01 | 96.8% | 67.0% |
| 3793885 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.66 | 60.0 | 4.48e-01 | 98.4% | 90.3% |
| 3400732 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.65 | 55.0 | 4.57e-01 | 100.0% | 80.8% |
| 3618760 | 109.4.1.155 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med23 | 0.63 | 47.0 | 3.15e-01 | 81.0% | 32.2% |
| 3582455 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.63 | 50.0 | 4.78e-01 | 87.3% | 94.7% |
| 3661216 | 109.4.1.1261 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long | 0.63 | 50.0 | 3.40e-01 | 88.9% | 23.9% |
| 3386014 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.63 | 49.0 | 3.17e-01 | 87.3% | 21.7% |
| 3993403 | 616.1.1.26 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › NPP-6_helical | 0.63 | 55.0 | 4.11e-01 | 98.4% | 77.5% |
| 3425354 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.62 | 55.0 | 3.77e-01 | 98.4% | 89.3% |
| 3636543 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.59 | 49.0 | 3.83e-01 | 92.1% | 67.4% |
| 3356206 | 109.4.1.1274 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, PPR_long | 0.56 | 41.0 | 2.48e-01 | 82.5% | 15.1% |
| 3709913 | 611.3.1.0 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.56 | 41.0 | 3.22e-01 | 81.0% | 39.3% |
D4
medium
residues 221-316
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3nyjA00 | 1.20.120.770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain | 0.74 | 58.0 | 4.67e-01 | 83.3% | 76.8% |
| 6o0aA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.72 | 40.0 | 3.39e-01 | 86.5% | 34.2% |
| 4hkaA01 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 48.0 | 3.37e-01 | 88.5% | 22.8% |
ECOD (2)
D5
medium
residues 317-376
Domain cluster:
representative
CATH (63)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.87 | 68.0 | 6.51e-01 | 81.7% | 79.1% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.87 | 67.0 | 4.34e-01 | 81.7% | 21.2% |
| 3b2eF00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.87 | 67.0 | 6.65e-01 | 81.7% | 85.5% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.86 | 65.0 | 5.33e-01 | 80.0% | 72.8% |
| 3fxdC00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.86 | 57.0 | 6.21e-01 | 80.0% | 82.0% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.85 | 65.0 | 4.59e-01 | 81.7% | 30.8% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.85 | 65.0 | 4.57e-01 | 81.7% | 30.3% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 64.0 | 5.85e-01 | 81.7% | 62.8% |
| 4a17U01 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.83 | 75.0 | 6.87e-01 | 100.0% | 90.9% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.83 | 63.0 | 5.43e-01 | 81.7% | 54.9% |
| 1vq8V00 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.82 | 70.0 | 6.82e-01 | 91.7% | 100.0% |
| 2xqyA01 | 3.30.500.50 | Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › | 0.82 | 72.0 | 5.08e-01 | 100.0% | 33.1% |
| 4cybD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.82 | 58.0 | 4.10e-01 | 75.0% | 36.3% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.82 | 62.0 | 6.14e-01 | 81.7% | 82.5% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.81 | 62.0 | 5.78e-01 | 81.7% | 78.7% |
| 4gczA03 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.81 | 61.0 | 5.99e-01 | 81.7% | 75.4% |
| 1ucuA01 | 6.10.280.190 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 61.0 | 5.84e-01 | 85.0% | 70.6% |
| 2fupA00 | 1.20.58.300 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like | 0.80 | 61.0 | 4.73e-01 | 81.7% | 41.7% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.80 | 68.0 | 5.65e-01 | 93.3% | 80.4% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 61.0 | 6.01e-01 | 83.3% | 82.5% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.79 | 58.0 | 5.88e-01 | 81.7% | 79.7% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 58.0 | 5.17e-01 | 78.3% | 62.7% |
| 3nkzA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.78 | 60.0 | 5.06e-01 | 81.7% | 53.6% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.78 | 58.0 | 4.47e-01 | 80.0% | 39.8% |
| 4x5mA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.78 | 70.0 | 6.21e-01 | 100.0% | 82.6% |
| 4hyjA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.77 | 60.0 | 3.94e-01 | 83.3% | 21.2% |
| 2yxyA01 | 1.10.287.880 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Hypothetical protein YfhH domain | 0.77 | 57.0 | 6.10e-01 | 78.3% | 98.0% |
| 1k8kG00 | 1.25.40.190 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Actin-related protein 2/3 complex subunit 5 | 0.77 | 63.0 | 4.76e-01 | 90.0% | 38.8% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.76 | 63.0 | 5.52e-01 | 90.0% | 66.7% |
| 4rflA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.76 | 55.0 | 3.84e-01 | 85.0% | 23.6% |
| 2c0gA02 | 1.20.1150.12 | Mainly Alpha › Up-down Bundle › Endoplasmic reticulum protein erp29 › Endoplasmic reticulum resident protein 29, C-terminal domain | 0.76 | 66.0 | 5.50e-01 | 98.3% | 57.5% |
| 4q20A01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.76 | 57.0 | 5.16e-01 | 81.7% | 59.8% |
| 3kr9A02 | 1.10.287.1890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 57.0 | 5.76e-01 | 81.7% | 96.7% |
| 3c4wB01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.75 | 51.0 | 3.52e-01 | 71.7% | 23.4% |
| 2yxhA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.74 | 65.0 | 5.23e-01 | 96.7% | 59.3% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.74 | 54.0 | 4.78e-01 | 80.0% | 54.0% |
| 7odyC01 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.74 | 61.0 | 5.26e-01 | 90.0% | 60.9% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.74 | 64.0 | 4.48e-01 | 98.3% | 67.0% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.73 | 62.0 | 5.48e-01 | 95.0% | 93.1% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.73 | 53.0 | 5.62e-01 | 80.0% | 92.2% |
| 4fxdA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.72 | 64.0 | 4.80e-01 | 100.0% | 88.9% |
| 2acxA01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.72 | 50.0 | 3.45e-01 | 73.3% | 22.9% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 60.0 | 5.09e-01 | 93.3% | 90.1% |
| 3uo2B02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.71 | 61.0 | 5.53e-01 | 98.3% | 88.1% |
| 2qgmA03 | 1.20.1440.30 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain | 0.71 | 59.0 | 4.81e-01 | 93.3% | 77.6% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.71 | 53.0 | 4.63e-01 | 81.7% | 80.9% |
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.70 | 61.0 | 3.70e-01 | 100.0% | 22.2% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.70 | 59.0 | 5.01e-01 | 98.3% | 66.0% |
| 3h6pC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.69 | 52.0 | 5.33e-01 | 80.0% | 87.5% |
| 3hpcX00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.69 | 51.0 | 3.76e-01 | 80.0% | 36.1% |
| 2i7uA00 | 6.10.250.1010 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.69 | 50.0 | 5.00e-01 | 80.0% | 88.7% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.68 | 59.0 | 5.35e-01 | 100.0% | 89.2% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.68 | 55.0 | 4.60e-01 | 90.0% | 59.2% |
| 1v4aA01 | 1.10.4050.10 | Mainly Alpha › Orthogonal Bundle › Nucleotidyltransferase substrate binding subunit/domain fold › Glutamine synthase adenylyltransferase GlnE | 0.66 | 58.0 | 4.74e-01 | 96.7% | 57.8% |
| 2lpeA01 | 6.10.140.1120 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 48.0 | 4.49e-01 | 85.0% | 61.5% |
| 3if8B02 | 1.20.58.730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 43.0 | 3.68e-01 | 70.0% | 43.0% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 55.0 | 4.64e-01 | 98.3% | 89.2% |
| 2x6hA03 | 1.10.1070.11 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain | 0.61 | 49.0 | 3.48e-01 | 91.7% | 52.5% |
| 3mlgA00 | 1.20.120.1980 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Knotted protein, ribbon-helix-helix DNA-binding domain | 0.61 | 49.0 | 3.56e-01 | 86.7% | 58.4% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.61 | 50.0 | 4.68e-01 | 98.3% | 89.9% |
| 3cwzB01 | 1.20.58.900 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain | 0.58 | 47.0 | 3.72e-01 | 96.7% | 82.2% |
| 2qkdA02 | 2.60.120.1040 | Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain | 0.57 | 44.0 | 3.48e-01 | 88.3% | 45.0% |
| 2c2uA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 45.0 | 3.43e-01 | 98.3% | 77.0% |
ECOD (62)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3239756 | 192.4.1.13 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Cactin_mid | 0.91 | 82.0 | 5.37e-01 | 100.0% | 25.7% |
| 4966215 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.89 | 69.0 | 4.87e-01 | 81.7% | 29.7% |
| 4672442 | 3004.1.1.2 ↗ | alpha bundles › Hypothetical protein YfhH, N-terminal domain › Hypothetical protein YfhH, N-terminal domain › Hypothetical protein YfhH, N-terminal domain › UVR | 0.89 | 72.0 | 6.63e-01 | 86.7% | 76.0% |
| 3815026 | 604.1.1.148 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N | 0.89 | 69.0 | 6.01e-01 | 81.7% | 62.4% |
| 3791628 | 1203.1.2.0 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 | 0.88 | 68.0 | 4.97e-01 | 81.7% | 33.8% |
| 3295251 | 605.1.1.185 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF7615 | 0.88 | 68.0 | 5.44e-01 | 81.7% | 44.5% |
| 4984327 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.87 | 68.0 | 5.49e-01 | 81.7% | 46.7% |
| 3931267 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.87 | 67.0 | 4.94e-01 | 81.7% | 42.1% |
| 4220356 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.87 | 67.0 | 4.06e-01 | 81.7% | 14.6% |
| 3349325 | 5086.1.1.135 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF7615 | 0.87 | 67.0 | 6.01e-01 | 81.7% | 61.3% |
| 4266268 | 192.8.1.376 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › RRP36 | 0.86 | 67.0 | 4.84e-01 | 81.7% | 32.7% |
| 3927560 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.86 | 66.0 | 6.69e-01 | 81.7% | 81.7% |
| 4056724 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.86 | 60.0 | 6.92e-01 | 73.3% | 97.8% |
| 3286299 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.86 | 66.0 | 5.30e-01 | 81.7% | 44.5% |
| 4039014 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.85 | 66.0 | 5.27e-01 | 81.7% | 44.5% |
| 4026159 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.85 | 62.0 | 6.74e-01 | 76.7% | 92.0% |
| 4572664 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.85 | 64.0 | 6.05e-01 | 80.0% | 68.6% |
| 3681259 | 5058.1.1.57 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › V-SNARE | 0.85 | 65.0 | 5.75e-01 | 81.7% | 57.6% |
| 3339348 | 606.1.1.12 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Rx_N | 0.84 | 66.0 | 5.02e-01 | 83.3% | 39.2% |
| 3180581 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.84 | 61.0 | 5.38e-01 | 81.7% | 54.1% |
| 1005577 | 3682.1.1.1 ↗ | alpha duplicates or obligate multimers › IcmQ dimerization domain › IcmQ dimerization domain › IcmQ dimerization domain › Dot_icm_IcmQ | 0.84 | 58.0 | 6.14e-01 | 71.7% | 96.2% |
| 3962893 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.83 | 64.0 | 5.44e-01 | 81.7% | 51.6% |
| 4473674 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.83 | 64.0 | 5.14e-01 | 81.7% | 44.5% |
| 3519492 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.83 | 62.0 | 4.90e-01 | 80.0% | 44.5% |
| 3336158 | 70.3.1.0 ↗ | beta barrels › beta-clip › SET domain-like › SET domain-like | 0.83 | 64.0 | 4.67e-01 | 81.7% | 33.1% |
| 3715996 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.82 | 64.0 | 6.89e-01 | 81.7% | 98.0% |
| 5042887 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.82 | 69.0 | 4.41e-01 | 91.7% | 67.9% |
| 4943086 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.80 | 67.0 | 6.38e-01 | 90.0% | 90.0% |
| 3194783 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.80 | 60.0 | 4.71e-01 | 80.0% | 40.9% |
| 4671 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.80 | 63.0 | 5.11e-01 | 85.0% | 46.4% |
| 3242683 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.80 | 62.0 | 5.32e-01 | 81.7% | 54.4% |
| 3700672 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.80 | 69.0 | 5.53e-01 | 95.0% | 83.5% |
| 4054043 | 192.1.1.2 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › GreA_GreB_N | 0.79 | 63.0 | 5.96e-01 | 85.0% | 84.3% |
| 3735658 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.79 | 61.0 | 4.87e-01 | 81.7% | 42.6% |
| 3614667 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.79 | 70.0 | 4.26e-01 | 96.7% | 54.8% |
| 3838686 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.78 | 59.0 | 5.91e-01 | 81.7% | 81.7% |
| 3774436 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.78 | 61.0 | 4.72e-01 | 91.7% | 38.5% |
| 3431415 | 6155.1.1.6 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921 | 0.78 | 71.0 | 6.25e-01 | 100.0% | 83.5% |
| 4539383 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.77 | 54.0 | 6.10e-01 | 73.3% | 100.0% |
| 4943532 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.77 | 58.0 | 5.58e-01 | 81.7% | 70.0% |
| 3744474 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.77 | 59.0 | 4.96e-01 | 90.0% | 50.0% |
| 4949374 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.77 | 58.0 | 5.68e-01 | 81.7% | 78.5% |
| 5057021 | 532.2.1.0 ↗ | alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains | 0.76 | 64.0 | 5.94e-01 | 91.7% | 73.3% |
| 3898383 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.76 | 67.0 | 5.27e-01 | 98.3% | 72.0% |
| 3641813 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.76 | 67.0 | 5.73e-01 | 98.3% | 84.2% |
| 4973156 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.76 | 61.0 | 3.63e-01 | 88.3% | 20.7% |
| 2055366 | 622.1.1.2 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HsbA | 0.75 | 65.0 | 5.84e-01 | 96.7% | 100.0% |
| 1000511 | 159.1.1.1 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG | 0.74 | 65.0 | 5.21e-01 | 96.7% | 58.8% |
| 3712097 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.74 | 55.0 | 4.87e-01 | 81.7% | 66.7% |
| 4928617 | 159.1.2.0 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related | 0.74 | 62.0 | 5.73e-01 | 91.7% | 78.7% |
| 3968401 | 109.4.1.86 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF924 | 0.73 | 65.0 | 4.55e-01 | 100.0% | 84.2% |
| 3740818 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.73 | 56.0 | 4.33e-01 | 91.7% | 35.9% |
| 4189213 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.73 | 54.0 | 4.96e-01 | 78.3% | 64.0% |
| 4017831 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.72 | 53.0 | 3.93e-01 | 81.7% | 31.0% |
| 3940791 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.71 | 60.0 | 5.12e-01 | 95.0% | 93.0% |
| 3686779 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.70 | 53.0 | 3.56e-01 | 81.7% | 27.4% |
| 3812952 | 633.26.1.0 ↗ | alpha bundles › Bromodomain-like › SidC lipid-binding domain › SidC lipid-binding domain | 0.70 | 63.0 | 4.34e-01 | 100.0% | 41.5% |
| 3932432 | 604.5.1.31 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TRAM_LAG1_CLN8 | 0.68 | 54.0 | 3.61e-01 | 90.0% | 31.6% |
| 3581778 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.68 | 58.0 | 3.91e-01 | 98.3% | 35.8% |
| 3964247 | 5065.1.1.2 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD | 0.65 | 48.0 | 3.10e-01 | 81.7% | 60.3% |
| 3805896 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.65 | 54.0 | 4.64e-01 | 91.7% | 87.4% |
| 3732730 | 243.9.1.2 ↗ | a+b two layers › Cystatin-like › Nuclease A inhibitor (NuiA)-related › Nuclease A inhibitor (NuiA)-related › Maf1 | 0.63 | 47.0 | 3.24e-01 | 81.7% | 77.3% |
D6
medium
residues 377-492
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vdyA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.68 | 48.0 | 4.56e-01 | 81.9% | 60.7% |
| 1sgmA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 47.0 | 4.09e-01 | 76.7% | 81.5% |
| 3lsjA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 45.0 | 4.11e-01 | 72.4% | 73.2% |
| 4c0eA02 | 1.25.40.800 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.63 | 51.0 | 4.18e-01 | 89.7% | 61.8% |
| 3dwlG00 | 1.25.40.190 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Actin-related protein 2/3 complex subunit 5 | 0.61 | 50.0 | 5.09e-01 | 94.8% | 91.2% |
| 1k8kG00 | 1.25.40.190 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Actin-related protein 2/3 complex subunit 5 | 0.60 | 50.0 | 4.72e-01 | 93.1% | 74.8% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.60 | 48.0 | 4.92e-01 | 84.5% | 90.9% |
| 4by6D02 | 1.25.40.800 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 51.0 | 4.20e-01 | 99.1% | 62.2% |
| 3jsjC00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 40.0 | 3.52e-01 | 74.1% | 80.3% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.56 | 42.0 | 3.58e-01 | 81.0% | 77.5% |
| 1dgfA03 | 1.20.1370.60 | Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › | 0.55 | 49.0 | 4.94e-01 | 99.1% | 97.4% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 45.0 | 4.14e-01 | 89.7% | 94.2% |
| 4jxtA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 46.0 | 4.52e-01 | 94.0% | 86.9% |
| 2a9uA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 37.0 | 3.64e-01 | 77.6% | 63.5% |
| 4hzuS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.54 | 41.0 | 3.68e-01 | 80.2% | 71.3% |
| 4wr4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 42.0 | 4.36e-01 | 84.5% | 92.4% |
| 1sz9C00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 44.0 | 4.20e-01 | 93.1% | 84.3% |
| 4flbA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 46.0 | 4.48e-01 | 97.4% | 86.3% |
| 3t8vA05 | 1.25.50.10 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain | 0.52 | 45.0 | 3.31e-01 | 97.4% | 56.6% |
| 3feyA02 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 46.0 | 3.95e-01 | 100.0% | 70.3% |
| 2a2fX02 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.52 | 43.0 | 4.25e-01 | 94.8% | 91.5% |
| 1l5jA01 | 1.25.40.310 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Aconitate B, HEAT-like domain | 0.52 | 40.0 | 3.66e-01 | 93.1% | 60.9% |
| 6tblB01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.51 | 40.0 | 4.16e-01 | 88.8% | 90.1% |
| 4yi7A02 | 3.40.1030.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 › Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0.51 | 40.0 | 3.15e-01 | 86.2% | 98.5% |
| 4d8mA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.50 | 41.0 | 3.45e-01 | 91.4% | 89.4% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3278097 | 601.1.1.61 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF8320 | 0.64 | 53.0 | 4.74e-01 | 89.7% | 79.4% |
| 3259396 | 109.4.1.58 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Not1 | 0.64 | 53.0 | 3.96e-01 | 90.5% | 44.8% |
| 4966134 | 109.4.1.3620 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26458 | 0.60 | 52.0 | 3.99e-01 | 96.6% | 46.8% |
| 3898465 | 109.4.1.517 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med24_N | 0.60 | 52.0 | 4.57e-01 | 99.1% | 76.8% |
| 3787899 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.58 | 40.0 | 3.80e-01 | 71.6% | 68.6% |
| 3461190 | 185.1.1.1 ↗ | alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › Tryp_alpha_amyl | 0.57 | 43.0 | 4.55e-01 | 81.0% | 92.0% |
| 4848241 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.57 | 48.0 | 4.13e-01 | 96.6% | 70.6% |
| 3168029 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.56 | 43.0 | 3.83e-01 | 87.9% | 56.4% |
| 3712542 | 109.4.1.1201 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RESC6 | 0.56 | 43.0 | 3.68e-01 | 93.1% | 48.7% |
| 3279074 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.56 | 40.0 | 3.84e-01 | 74.1% | 72.9% |
| 3507662 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.55 | 46.0 | 4.33e-01 | 92.2% | 75.0% |
| 3173970 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 46.0 | 4.15e-01 | 94.0% | 67.6% |
| 3601985 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 47.0 | 3.89e-01 | 98.3% | 50.5% |
| 4937823 | 3558.1.1.0 ↗ | alpha arrays › HSDR subunit helical domain › HSDR subunit helical domain › HSDR subunit helical domain | 0.55 | 38.0 | 4.08e-01 | 73.3% | 93.0% |
| 3728390 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.54 | 44.0 | 4.22e-01 | 98.3% | 76.3% |
| 3778248 | 109.54.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 | 0.54 | 43.0 | 2.80e-01 | 87.9% | 18.2% |
| 5056116 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 45.0 | 3.81e-01 | 94.0% | 53.0% |
| 3786775 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.54 | 43.0 | 2.83e-01 | 99.1% | 18.9% |
| 3447221 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.54 | 39.0 | 3.99e-01 | 93.1% | 77.4% |
| 3460252 | 109.54.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 | 0.54 | 44.0 | 2.97e-01 | 95.7% | 21.6% |
| 3632466 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.53 | 48.0 | 4.12e-01 | 100.0% | 71.4% |
| 3298666 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.53 | 44.0 | 2.90e-01 | 94.8% | 20.2% |
| 4029367 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 45.0 | 2.93e-01 | 98.3% | 20.2% |
| 3565999 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 45.0 | 2.77e-01 | 96.6% | 21.2% |
| 4435347 | 6035.1.1.2 ↗ | alpha bundles › Primase helical domain › Primase helical domain › Primase helical domain › RepB_primase_C | 0.51 | 35.0 | 3.71e-01 | 100.0% | 81.0% |
| 3748523 | 109.4.1.22 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N | 0.50 | 43.0 | 3.31e-01 | 94.8% | 49.8% |
D7
medium
residues 493-584
Domain cluster:
representative
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3jvoA00 | 1.10.3230.30 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein yqbg › Phage gp6-like head-tail connector protein | 0.68 | 48.0 | 4.74e-01 | 72.8% | 69.8% |
| 3t38A01 | 1.10.8.1060 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Corynebacterium glutamicum thioredoxin-dependent arsenate reductase, N-terminal domain | 0.67 | 43.0 | 4.76e-01 | 71.7% | 84.5% |
| 5xe7A01 | 1.20.140.160 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain | 0.66 | 39.0 | 3.39e-01 | 70.7% | 37.3% |
| 3te6A02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.66 | 50.0 | 4.73e-01 | 81.5% | 70.5% |
| 2gfhA02 | 1.20.120.710 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Haloacid dehalogenase hydrolase-like domain | 0.64 | 40.0 | 4.16e-01 | 72.8% | 66.3% |
| 2z15A00 | 3.90.640.90 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › Anti-proliferative protein, N-terminal domain | 0.64 | 46.0 | 4.27e-01 | 76.1% | 62.2% |
| 7krzA02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.63 | 45.0 | 4.73e-01 | 80.4% | 82.1% |
| 3h4cA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.63 | 41.0 | 4.09e-01 | 73.9% | 63.5% |
| 1qzmA00 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.63 | 48.0 | 4.84e-01 | 84.8% | 79.8% |
| 1px5A02 | 1.10.1410.20 | Mainly Alpha › Orthogonal Bundle › Poly(a)-polymerase, middle domain › 2'-5'-oligoadenylate synthetase 1, domain 2 | 0.60 | 46.0 | 3.70e-01 | 82.6% | 67.2% |
| 1fx8A00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.59 | 43.0 | 3.16e-01 | 77.2% | 81.9% |
| 3vkgA15 | 1.10.8.1220 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.58 | 40.0 | 4.05e-01 | 72.8% | 74.5% |
| 5xs2B02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.57 | 42.0 | 3.75e-01 | 78.3% | 54.5% |
| 2c61A00 | 3.40.50.12240 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.57 | 45.0 | 2.95e-01 | 87.0% | 39.0% |
| 3s6jE02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.55 | 34.0 | 3.98e-01 | 71.7% | 85.5% |
| 1xfiA02 | 1.20.1700.10 | Mainly Alpha › Up-down Bundle › AF1104-like › AF1104-like | 0.55 | 39.0 | 3.98e-01 | 76.1% | 87.8% |
| 4u04A02 | 1.10.3290.10 | Mainly Alpha › Orthogonal Bundle › Fic-like fold › Fido-like domain | 0.54 | 37.0 | 2.77e-01 | 71.7% | 34.1% |
| 1l7vA00 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.54 | 44.0 | 3.07e-01 | 90.2% | 93.8% |
| 1ztdA00 | 1.10.1520.20 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III | 0.54 | 41.0 | 3.82e-01 | 84.8% | 83.2% |
| 1winA01 | 3.30.479.30 | Alpha Beta › 2-Layer Sandwich › Tetrahydropterin Synthase; Chain A › Band 7 domain | 0.53 | 40.0 | 3.78e-01 | 82.6% | 80.3% |
| 2xqyA01 | 3.30.500.50 | Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › | 0.53 | 37.0 | 3.02e-01 | 73.9% | 83.7% |
| 7yq0B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 40.0 | 3.40e-01 | 84.8% | 100.0% |
| 3fbxA00 | 3.60.60.30 | Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › | 0.50 | 41.0 | 2.63e-01 | 92.4% | 40.2% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4434200 | 142.1.1.5 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › SRI | 0.70 | 51.0 | 4.88e-01 | 78.3% | 71.8% |
| 377920 | 4275.1.1.1 ↗ | alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Phage_connect_1 | 0.68 | 48.0 | 4.72e-01 | 72.8% | 69.1% |
| 3676159 | 148.1.3.46 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Cdc6-ORC-like_ATPase_lid | 0.65 | 49.0 | 4.93e-01 | 80.4% | 90.5% |
| 4624390 | 142.1.1.1 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r1_2,Sigma70_r2 | 0.64 | 47.0 | 4.38e-01 | 77.2% | 61.7% |
| 3972284 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.64 | 47.0 | 4.37e-01 | 77.2% | 61.7% |
| 4978508 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.63 | 46.0 | 4.70e-01 | 82.6% | 78.9% |
| 4232234 | 101.1.2.309 ↗ | alpha arrays › HTH › HTH › winged helix domain › GPAT_C | 0.63 | 44.0 | 3.45e-01 | 71.7% | 93.7% |
| 3410545 | 108.2.1.0 ↗ | alpha arrays › EF-hand › Insect pheromone/odorant-binding proteins › Insect pheromone/odorant-binding proteins | 0.62 | 43.0 | 4.00e-01 | 70.7% | 59.1% |
| 3387918 | 207.9.1.3 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pentapeptide repeats › Pentapeptide repeats › Pentapeptide_3 | 0.62 | 45.0 | 3.14e-01 | 77.2% | 22.8% |
| 3993316 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.61 | 50.0 | 3.46e-01 | 90.2% | 83.7% |
| 3885862 | 524.1.1.0 ↗ | alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p | 0.61 | 54.0 | 4.55e-01 | 98.9% | 61.9% |
| 3623336 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.60 | 53.0 | 4.06e-01 | 100.0% | 78.7% |
| 5073287 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.60 | 46.0 | 3.71e-01 | 81.5% | 60.6% |
| 3164754 | 1078.1.1.7 ↗ | extended segments › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit › PHO4 | 0.59 | 46.0 | 3.20e-01 | 83.7% | 93.2% |
| 4634670 | 5067.1.1.1 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ACR_tran | 0.59 | 53.0 | 4.03e-01 | 100.0% | 88.4% |
| 4010442 | 5067.1.1.1 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ACR_tran | 0.59 | 53.0 | 4.03e-01 | 100.0% | 88.4% |
| 3503299 | 148.1.3.19 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 | 0.58 | 44.0 | 4.41e-01 | 82.6% | 77.9% |
| 5045625 | 2004.1.1.76 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 | 0.58 | 41.0 | 2.66e-01 | 75.0% | 19.8% |
| 3366549 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.58 | 41.0 | 3.81e-01 | 73.9% | 60.9% |
| 3620740 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.57 | 43.0 | 4.27e-01 | 79.3% | 81.1% |
| 4565834 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.56 | 40.0 | 3.40e-01 | 73.9% | 86.0% |
| 5020092 | 5067.1.1.4 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL | 0.56 | 49.0 | 3.74e-01 | 100.0% | 71.1% |
| 3287220 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.55 | 39.0 | 2.80e-01 | 73.9% | 72.1% |
| 3890757 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.55 | 35.0 | 3.63e-01 | 97.8% | 66.7% |
| 3575986 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.55 | 48.0 | 3.88e-01 | 98.9% | 58.5% |
| 4950905 | 3896.1.2.6 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase › DUF92 | 0.55 | 42.0 | 3.61e-01 | 82.6% | 58.0% |
| 3224983 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.53 | 39.0 | 3.12e-01 | 77.2% | 84.9% |
| 3488421 | 210.1.2.6 ↗ | a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › Phospholip_B | 0.53 | 44.0 | 3.17e-01 | 96.7% | 78.9% |
| 4576714 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.52 | 37.0 | 3.27e-01 | 76.1% | 53.8% |
| 5003451 | 186.1.1.4 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_4 | 0.52 | 39.0 | 3.61e-01 | 82.6% | 72.0% |
| 3458610 | 101.1.10.13 ↗ | alpha arrays › HTH › HTH › Cyclin-like › DUF3452 | 0.50 | 39.0 | 3.50e-01 | 83.7% | 84.6% |