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MT764845.1__QNN99842.1__P67b_00083__00083
Bact-VirMT764845.1__QNN99842.1__P67b_00083__00083
Identity
- Accession:
- MT764845 ↗
- Kingdom:
- phage
Quality
70.8
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 303-362
Domain cluster:
representative
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4g6dB02 | 6.10.140.1800 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 54.0 | 4.91e-01 | 78.3% | 59.3% |
| 2hh6A00 | 1.10.1900.10 | Mainly Alpha › Orthogonal Bundle › c-terminal domain of poly(a) binding protein › c-terminal domain of poly(a) binding protein | 0.70 | 60.0 | 4.99e-01 | 100.0% | 69.4% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.68 | 53.0 | 4.58e-01 | 85.0% | 92.6% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.67 | 53.0 | 4.82e-01 | 86.7% | 100.0% |
| 3deeA01 | 1.10.150.690 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 | 0.63 | 50.0 | 4.45e-01 | 88.3% | 81.4% |
| 3dcfA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 51.0 | 3.93e-01 | 98.3% | 57.0% |
| 6h7bA01 | 1.10.1900.10 | Mainly Alpha › Orthogonal Bundle › c-terminal domain of poly(a) binding protein › c-terminal domain of poly(a) binding protein | 0.58 | 44.0 | 4.15e-01 | 85.0% | 95.9% |
| 1zs3A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 48.0 | 3.48e-01 | 91.7% | 50.3% |
| 4ceiA03 | 6.10.250.2380 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.58 | 47.0 | 3.87e-01 | 91.7% | 67.9% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 46.0 | 3.71e-01 | 93.3% | 96.7% |
| 3d8bB02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.56 | 40.0 | 3.69e-01 | 78.3% | 81.7% |
| 5oklA01 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.55 | 41.0 | 3.58e-01 | 85.0% | 66.3% |
| 3kbbA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.54 | 38.0 | 3.70e-01 | 76.7% | 68.6% |
| 3p01A01 | 6.10.140.590 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 45.0 | 4.05e-01 | 91.7% | 85.5% |
| 2hdoA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.54 | 36.0 | 3.62e-01 | 73.3% | 67.2% |
| 5nohA00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.53 | 37.0 | 3.22e-01 | 76.7% | 83.5% |
| 3py8A04 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.53 | 38.0 | 3.04e-01 | 81.7% | 77.1% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.52 | 42.0 | 3.71e-01 | 86.7% | 67.1% |
| 7qovB01 | 1.10.472.20 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Nitrile hydratase, beta subunit | 0.52 | 40.0 | 3.41e-01 | 88.3% | 61.1% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4013656 | 170.1.1.0 ↗ | alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C | 0.73 | 61.0 | 6.33e-01 | 96.7% | 100.0% |
| 3353338 | 170.1.1.0 ↗ | alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C | 0.70 | 49.0 | 5.48e-01 | 85.0% | 100.0% |
| 5084048 | 3831.1.1.15 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › HAAS | 0.69 | 48.0 | 4.24e-01 | 75.0% | 51.8% |
| 4279016 | 101.1.1.31 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 | 0.68 | 53.0 | 4.78e-01 | 81.7% | 85.0% |
| 4120848 | 101.1.1.310 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › UPF0137 | 0.67 | 56.0 | 4.19e-01 | 96.7% | 39.4% |
| 3973360 | 101.1.1.42 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 | 0.66 | 48.0 | 4.59e-01 | 76.7% | 91.4% |
| 3958254 | 3317.1.1.0 ↗ | alpha arrays › KorB C-terminal domain-like › KorB C-terminal domain › KorB C-terminal domain | 0.63 | 45.0 | 4.29e-01 | 75.0% | 80.0% |
| 3519643 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 45.0 | 3.54e-01 | 76.7% | 43.2% |
| 4001307 | 632.2.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains | 0.62 | 51.0 | 4.68e-01 | 93.3% | 78.8% |
| 3478089 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.62 | 52.0 | 4.54e-01 | 100.0% | 91.9% |
| 4032129 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.61 | 46.0 | 4.57e-01 | 85.0% | 100.0% |
| 5045752 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.56 | 43.0 | 3.13e-01 | 90.0% | 51.3% |
| 4997121 | 101.1.2.136 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_20 | 0.55 | 43.0 | 3.15e-01 | 90.0% | 53.7% |
| 3840064 | 192.24.1.0 ↗ | alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain | 0.53 | 42.0 | 3.59e-01 | 90.0% | 53.7% |
| 5039812 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.52 | 40.0 | 3.08e-01 | 88.3% | 67.1% |
D2
medium
residues 121-222
D3
medium
residues 237-296
Domain cluster:
representative
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.75 | 55.0 | 4.62e-01 | 78.3% | 77.5% |
| 2ptfB02 | 1.20.58.290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. | 0.73 | 53.0 | 5.45e-01 | 78.3% | 94.7% |
| 2nr4A02 | 1.20.58.290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. | 0.72 | 50.0 | 5.08e-01 | 73.3% | 89.7% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.72 | 56.0 | 4.01e-01 | 85.0% | 76.6% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.70 | 54.0 | 4.61e-01 | 83.3% | 86.6% |
| 1iurA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.70 | 49.0 | 4.90e-01 | 75.0% | 93.7% |
| 2bvlA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 54.0 | 4.80e-01 | 85.0% | 72.1% |
| 2d9jA02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.69 | 55.0 | 5.03e-01 | 86.7% | 72.2% |
| 7wf8B01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.67 | 55.0 | 4.37e-01 | 90.0% | 45.5% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.67 | 54.0 | 4.51e-01 | 91.7% | 60.6% |
| 2b1eA01 | 1.20.58.1150 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 48.0 | 4.37e-01 | 80.0% | 74.4% |
| 2gnoA03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.66 | 48.0 | 4.08e-01 | 78.3% | 59.0% |
| 3nkyA03 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.66 | 52.0 | 4.91e-01 | 93.3% | 72.6% |
| 2ggfA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.65 | 53.0 | 4.09e-01 | 95.0% | 40.1% |
| 2acxA01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.65 | 53.0 | 3.60e-01 | 88.3% | 27.8% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 51.0 | 3.84e-01 | 86.7% | 86.6% |
| 3urzA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.64 | 56.0 | 3.91e-01 | 100.0% | 45.0% |
| 3pvuA02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.64 | 53.0 | 4.83e-01 | 91.7% | 73.8% |
| 2ds2D01 | 1.10.110.10 | Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins | 0.64 | 43.0 | 4.45e-01 | 70.0% | 93.0% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.64 | 48.0 | 4.30e-01 | 85.0% | 75.8% |
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.64 | 49.0 | 4.61e-01 | 86.7% | 74.7% |
| 2rpaA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 46.0 | 4.32e-01 | 80.0% | 81.8% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 45.0 | 3.92e-01 | 80.0% | 82.5% |
| 3nynA03 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.63 | 51.0 | 4.58e-01 | 88.3% | 70.4% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 49.0 | 3.69e-01 | 85.0% | 89.9% |
| 1sqgA01 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.63 | 44.0 | 3.43e-01 | 75.0% | 84.4% |
| 2kxpA01 | 3.30.1140.60 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › F-actin capping protein, alpha subunit | 0.62 | 47.0 | 3.98e-01 | 85.0% | 87.9% |
| 1vt0M05 | 6.10.280.90 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 42.0 | 3.95e-01 | 90.0% | 56.8% |
| 1aj3A00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 43.0 | 3.78e-01 | 78.3% | 86.7% |
| 1rw9A01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.60 | 53.0 | 3.25e-01 | 100.0% | 32.2% |
| 3qnfA04 | 1.10.3480.20 | Mainly Alpha › Orthogonal Bundle › TorD-like › | 0.59 | 51.0 | 3.71e-01 | 100.0% | 66.7% |
| 2r5sA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 50.0 | 4.47e-01 | 96.7% | 96.6% |
| 7qihA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 48.0 | 4.19e-01 | 96.7% | 84.2% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.58 | 47.0 | 4.30e-01 | 90.0% | 69.1% |
| 4jgiB02 | 3.40.50.280 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain | 0.58 | 46.0 | 3.66e-01 | 88.3% | 49.2% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 43.0 | 3.94e-01 | 85.0% | 75.3% |
| 2p58C00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 49.0 | 4.02e-01 | 96.7% | 74.1% |
| 6oibA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.56 | 47.0 | 3.53e-01 | 93.3% | 48.3% |
| 3c4wB01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.55 | 39.0 | 2.78e-01 | 76.7% | 35.0% |
| 2gxaE01 | 1.10.10.510 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain | 0.54 | 36.0 | 3.46e-01 | 71.7% | 63.0% |
| 3hjlA03 | 1.20.5.2020 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.51 | 34.0 | 3.65e-01 | 75.0% | 100.0% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3959009 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.80 | 53.0 | 5.20e-01 | 81.7% | 63.1% |
| 3277420 | 109.26.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains | 0.75 | 64.0 | 4.41e-01 | 95.0% | 33.2% |
| 4975245 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.73 | 57.0 | 4.98e-01 | 83.3% | 80.7% |
| 2573754 | 189.1.1.1 ↗ | alpha bundles › GTPase activation domain, GAP › GTPase activation domain, GAP › GTPase activation domain, GAP › RasGAP | 0.73 | 64.0 | 5.70e-01 | 100.0% | 93.2% |
| 3390932 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.71 | 52.0 | 4.61e-01 | 80.0% | 74.4% |
| 3809170 | 3826.1.1.92 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › WAV3_C | 0.70 | 54.0 | 5.09e-01 | 85.0% | 82.7% |
| 4250142 | 4030.1.1.2 ↗ | alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › F-actin_cap_A | 0.69 | 49.0 | 5.08e-01 | 75.0% | 87.3% |
| 5029931 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.68 | 47.0 | 4.50e-01 | 71.7% | 94.3% |
| 3288130 | 604.17.1.0 ↗ | alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like | 0.68 | 48.0 | 5.04e-01 | 76.7% | 83.6% |
| 4350523 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.67 | 46.0 | 3.93e-01 | 71.7% | 55.0% |
| 3939027 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.66 | 46.0 | 2.74e-01 | 71.7% | 11.9% |
| 351198 | 109.1.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C | 0.66 | 57.0 | 4.37e-01 | 100.0% | 52.4% |
| 4887646 | 4030.1.1.2 ↗ | alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › F-actin_cap_A | 0.66 | 47.0 | 4.84e-01 | 75.0% | 82.1% |
| 3599766 | 109.26.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains | 0.66 | 56.0 | 3.19e-01 | 100.0% | 14.1% |
| 3668286 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.65 | 50.0 | 4.81e-01 | 86.7% | 92.9% |
| 4997940 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.64 | 50.0 | 4.24e-01 | 85.0% | 68.0% |
| 3600071 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.64 | 46.0 | 4.57e-01 | 80.0% | 81.5% |
| 5047565 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 56.0 | 4.60e-01 | 100.0% | 56.4% |
| 3188614 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.63 | 50.0 | 4.71e-01 | 88.3% | 77.3% |
| 3794795 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.63 | 47.0 | 4.05e-01 | 83.3% | 84.0% |
| None | — | 0.62 | 53.0 | 3.68e-01 | 100.0% | 32.7% | |
| 3727500 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.62 | 51.0 | 4.86e-01 | 91.7% | 85.7% |
| 5061038 | 109.4.1.202 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 | 0.61 | 48.0 | 3.33e-01 | 93.3% | 30.4% |
| 4944677 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.61 | 46.0 | 3.98e-01 | 85.0% | 87.0% |
| 3952621 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.59 | 43.0 | 4.13e-01 | 76.7% | 73.9% |
| 3510785 | 3345.1.1.1 ↗ | alpha arrays › MRG domain › MRG domain › MRG domain › MRG | 0.57 | 41.0 | 3.12e-01 | 78.3% | 53.5% |
| 3508547 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.57 | 41.0 | 3.48e-01 | 78.3% | 90.5% |
| 3725274 | 182.1.1.1 ↗ | alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain › FAD_binding_7 | 0.55 | 45.0 | 2.90e-01 | 100.0% | 19.8% |
D4
medium
residues 396-459
Domain cluster:
representative
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5ha6B00 | 1.10.287.210 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.81 | 40.0 | 3.66e-01 | 100.0% | 39.2% |
| 2f8lA01 | 1.10.150.470 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.72 | 52.0 | 4.86e-01 | 90.6% | 61.7% |
| 1wmgA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.67 | 48.0 | 4.29e-01 | 76.6% | 81.1% |
| 3ousA00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 50.0 | 4.64e-01 | 93.8% | 67.1% |
| 8ctsB01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 48.0 | 4.35e-01 | 90.6% | 59.8% |
| 6wshA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.64 | 46.0 | 4.90e-01 | 76.6% | 90.9% |
| 1mswD04 | 1.10.287.280 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 49.0 | 4.64e-01 | 87.5% | 71.8% |
| 6lumD01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.62 | 50.0 | 4.02e-01 | 87.5% | 80.8% |
| 3dddA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.60 | 46.0 | 3.69e-01 | 82.8% | 80.0% |
| 2kw3C00 | 6.10.290.30 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulatory factor X-associated C-terminal binding domain | 0.60 | 38.0 | 3.89e-01 | 73.4% | 66.1% |
| 6sy1A02 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.59 | 43.0 | 2.69e-01 | 78.1% | 85.6% |
| 3iq1B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 46.0 | 3.48e-01 | 85.9% | 81.1% |
| 1s8nA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 46.0 | 4.79e-01 | 85.9% | 96.6% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 43.0 | 3.70e-01 | 81.2% | 84.5% |
| 2g80A02 | 1.10.720.60 | Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › | 0.54 | 42.0 | 3.97e-01 | 82.8% | 73.1% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 46.0 | 3.61e-01 | 100.0% | 78.8% |
| 3bvxA02 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.53 | 46.0 | 3.83e-01 | 96.9% | 82.0% |
| 2c42A03 | 3.40.920.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | 0.52 | 46.0 | 3.21e-01 | 100.0% | 36.8% |
| 2qguA02 | 1.10.10.640 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › phospholipid-binding protein | 0.51 | 39.0 | 3.73e-01 | 85.9% | 97.4% |
| 3nbiA01 | 1.10.8.1020 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain | 0.51 | 39.0 | 4.01e-01 | 84.4% | 96.6% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4009368 | 2007.1.14.7 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › HGD-D | 0.71 | 53.0 | 3.64e-01 | 79.7% | 23.9% |
| 3597591 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.69 | 50.0 | 4.94e-01 | 78.1% | 81.4% |
| 3657184 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.68 | 51.0 | 4.26e-01 | 79.7% | 55.5% |
| 3231388 | 103.4.1.3 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Med15_N | 0.68 | 55.0 | 5.34e-01 | 87.5% | 91.4% |
| 3475373 | 1128.1.1.2 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 | 0.67 | 49.0 | 4.69e-01 | 79.7% | 76.0% |
| 3740646 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.67 | 49.0 | 4.59e-01 | 79.7% | 75.0% |
| 4959289 | 606.1.1.0 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain | 0.66 | 51.0 | 4.45e-01 | 100.0% | 55.8% |
| 3706847 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.66 | 52.0 | 3.40e-01 | 93.8% | 20.4% |
| 3738479 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.65 | 47.0 | 4.38e-01 | 79.7% | 69.4% |
| 5013034 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.65 | 50.0 | 4.52e-01 | 92.2% | 60.0% |
| 3591103 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.64 | 50.0 | 3.37e-01 | 93.8% | 22.0% |
| 3219902 | 1128.1.1.2 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 | 0.63 | 46.0 | 4.36e-01 | 79.7% | 71.2% |
| 4861051 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.63 | 47.0 | 4.38e-01 | 81.2% | 74.1% |
| 4945443 | 2004.5.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain | 0.62 | 52.0 | 3.74e-01 | 93.8% | 72.6% |
| 3261908 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.62 | 47.0 | 4.58e-01 | 85.9% | 73.3% |
| 3431353 | 1128.1.1.10 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › VIN3_C | 0.61 | 42.0 | 4.18e-01 | 75.0% | 70.0% |
| 3931089 | 4336.2.1.1 ↗ | alpha duplicates or obligate multimers › YheA/YmcA-like › Protein SUS1 › Protein SUS1 › EnY2 | 0.61 | 42.0 | 3.76e-01 | 71.9% | 93.3% |
| 3709588 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.60 | 46.0 | 4.26e-01 | 81.2% | 80.0% |
| 3688768 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.60 | 48.0 | 3.96e-01 | 93.8% | 47.5% |
| 5051347 | 101.1.9.0 ↗ | alpha arrays › HTH › HTH › Putative DNA-binding domain | 0.60 | 41.0 | 4.01e-01 | 75.0% | 90.7% |
| 3930859 | 190.1.1.1 ↗ | alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box | 0.60 | 38.0 | 3.65e-01 | 70.3% | 54.7% |
| 5042372 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.59 | 46.0 | 3.98e-01 | 93.8% | 52.9% |
| 4239905 | 103.1.1.6 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › RuvA_C | 0.59 | 40.0 | 4.34e-01 | 73.4% | 85.2% |
| 4177433 | 190.1.1.0 ↗ | alpha arrays › HMG-box-like › HMG-box › HMG-box | 0.58 | 37.0 | 3.69e-01 | 70.3% | 60.0% |
| 4453675 | 190.1.1.1 ↗ | alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box | 0.58 | 38.0 | 3.79e-01 | 70.3% | 64.6% |
| 4952111 | 101.1.2.21 ↗ | alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repress | 0.58 | 50.0 | 3.91e-01 | 100.0% | 48.3% |
| 3502686 | 2484.1.1.88 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › ParM_N | 0.58 | 45.0 | 3.45e-01 | 89.1% | 47.9% |
| 3925923 | 130.1.1.0 ↗ | alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif | 0.57 | 40.0 | 3.93e-01 | 73.4% | 71.4% |
| 3269193 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.56 | 40.0 | 3.22e-01 | 76.6% | 66.7% |
| 3944747 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.55 | 42.0 | 3.13e-01 | 87.5% | 30.3% |
| 3945891 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.54 | 42.0 | 3.38e-01 | 92.2% | 88.0% |
| 4420108 | 103.1.1.6 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › RuvA_C | 0.54 | 40.0 | 4.22e-01 | 78.1% | 90.9% |
| 3395749 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.53 | 41.0 | 3.33e-01 | 87.5% | 41.5% |
| 3937791 | 633.10.1.18 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › THU_Piezo1 | 0.52 | 38.0 | 3.44e-01 | 82.8% | 53.0% |
| 3293474 | 143.1.1.1 ↗ | alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain › PABP | 0.51 | 39.0 | 3.76e-01 | 85.9% | 73.3% |