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MT833387.1__QOI58120.1__HF4s_0016__00016

Bact-Vir

MT833387.1__QOI58120.1__HF4s_0016__00016

Identity

Accession:
MT833387 ↗
Kingdom:
phage

Quality

94.2 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Lederbergvirus› Escherichia_phage_HF4s

TaxID: 2775262

Cluster

View cluster (3 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 330-409
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3e11A00 3.30.2010.20 Alpha Beta › 2-Layer Sandwich › Zincin-like › 0.73 32.0 2.80e-01 80.0% 29.8%
1j31A00 3.60.110.10 Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase 0.69 53.0 3.63e-01 81.2% 28.0%
1emsA01 3.60.110.10 Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase 0.67 52.0 3.52e-01 81.2% 26.2%
3hpaA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.61 42.0 2.84e-01 80.0% 18.1%
6imeA01 3.40.1180.10 Alpha Beta › 3-Layer(aba) Sandwich › Undecaprenyl pyrophosphate synthetase › Decaprenyl diphosphate synthase-like 0.60 46.0 3.22e-01 82.5% 39.8%
2pg3A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.58 43.0 3.22e-01 86.3% 29.5%
1j0aA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 36.0 3.29e-01 73.8% 47.1%
2c5sA02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.58 41.0 3.03e-01 82.5% 29.1%
4d8tA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 35.0 3.20e-01 73.8% 44.0%
4kfuA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 39.0 2.96e-01 77.5% 28.3%
3hbaA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.55 44.0 3.39e-01 88.7% 89.0%
2xn1A02 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 40.0 2.76e-01 80.0% 24.1%
3a0rA03 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.54 44.0 3.64e-01 90.0% 92.5%
3obwA02 3.30.420.60 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2 0.54 37.0 3.27e-01 86.3% 47.5%
1id0A00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.54 42.0 3.54e-01 87.5% 95.2%
3n05A01 3.60.110.10 Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase 0.53 42.0 2.85e-01 85.0% 43.9%
3etnB00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.53 42.0 3.27e-01 90.0% 89.4%
3cvjC00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.53 43.0 3.17e-01 93.8% 99.2%
5mmjb01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.52 42.0 3.57e-01 90.0% 95.0%
4rrfA01 3.50.80.10 Alpha Beta › 3-Layer(bba) Sandwich › D-tyrosyl-trna(Tyr) Deacylase; Chain: A; › D-tyrosyl-tRNA(Tyr) deacylase 0.51 38.0 3.33e-01 82.5% 50.7%
1erzA00 3.60.110.10 Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase 0.51 40.0 2.73e-01 86.3% 31.4%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4455196 246.1.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase 0.67 56.0 3.69e-01 90.0% 30.0%
3483668 246.1.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase 0.66 50.0 3.34e-01 81.2% 57.1%
4014653 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.65 50.0 3.18e-01 83.7% 20.7%
4029325 2004.1.1.94 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATP_bind_1 0.58 40.0 2.73e-01 72.5% 25.3%
3684539 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.58 47.0 3.46e-01 91.3% 38.7%
3495618 2002.1.1.30 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_18 0.56 42.0 2.80e-01 81.2% 18.9%
3593835 246.2.1.0 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases 0.55 40.0 2.70e-01 82.5% 19.4%
3680025 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.55 39.0 3.12e-01 76.2% 39.4%
3402694 2004.1.1.98 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad17 0.54 44.0 3.33e-01 88.7% 72.3%
3979054 246.1.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase 0.53 41.0 2.89e-01 83.7% 32.7%
3729027 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.53 44.0 2.97e-01 93.8% 32.6%
4536593 7523.1.1.4 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_3 0.51 43.0 3.04e-01 93.8% 96.5%
4938435 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.50 44.0 3.14e-01 97.5% 79.2%
D2 medium residues 1-127
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF19528.5 best DUF6056 52.5 5.00e-14 100.0% 31.4%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gfhA02 1.20.120.710 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Haloacid dehalogenase hydrolase-like domain 0.63 33.0 3.92e-01 99.2% 74.4%
3jsbA01 1.20.1440.300 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain 0.60 30.0 3.61e-01 89.0% 71.6%
1fadA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.57 36.0 4.06e-01 85.0% 84.2%
2of5H00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.55 36.0 4.03e-01 85.8% 85.0%
2di3B02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.53 36.0 3.43e-01 97.6% 55.5%
3lcvB01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.53 25.0 3.31e-01 86.6% 91.2%
2icwG02 1.10.10.530 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › mam-mhc complex, Chain D, Domain 2 0.51 30.0 3.54e-01 74.0% 83.1%
4a2qA01 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.51 33.0 3.68e-01 88.2% 86.0%
2yufA00 1.20.120.2010 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NAB conserved domain 2 0.51 41.0 4.05e-01 96.9% 79.6%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3977366 3352.1.1.10 ↗ alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › DUF6056 0.95 93.0 6.29e-01 100.0% 35.5%
3979915 3352.1.1.10 ↗ alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › DUF6056 0.95 92.0 6.31e-01 100.0% 36.4%
3212544 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 37.0 3.37e-01 94.5% 49.4%
3943534 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 38.0 3.39e-01 94.5% 46.7%
3290227 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 39.0 3.49e-01 94.5% 49.5%
3400281 5050.1.1.1 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.54 39.0 3.27e-01 100.0% 41.7%
5003187 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 38.0 3.11e-01 96.9% 37.3%
3941569 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 37.0 3.34e-01 95.3% 48.9%
4931586 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 39.0 3.46e-01 100.0% 51.3%
3985920 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 39.0 3.34e-01 100.0% 46.5%
3290460 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 38.0 3.43e-01 100.0% 52.1%
3385580 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 39.0 3.41e-01 100.0% 49.3%
3287705 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 40.0 3.36e-01 96.9% 45.7%
3968913 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 39.0 3.33e-01 100.0% 48.1%
4032748 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 38.0 3.31e-01 100.0% 48.3%
5009628 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 40.0 3.54e-01 100.0% 54.9%
4460786 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 37.0 3.38e-01 100.0% 53.5%
4255458 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 38.0 3.31e-01 100.0% 48.8%
5001242 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.51 38.0 3.65e-01 78.0% 82.1%
5025965 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 37.0 3.30e-01 100.0% 50.3%
3603443 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 38.0 3.38e-01 100.0% 53.2%
3398827 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 38.0 3.33e-01 100.0% 50.2%
5013443 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.50 33.0 2.95e-01 90.6% 44.9%
D3 medium residues 128-209
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF19528.5 best DUF6056 34.8 1.20e-08 97.6% 15.7%
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1elkA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.73 60.0 4.92e-01 92.7% 49.0%
1he8A03 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.71 58.0 5.24e-01 89.0% 65.8%
4hwdD00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.70 53.0 5.13e-01 79.3% 87.8%
5mdtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.69 61.0 5.04e-01 100.0% 57.2%
3pqaB01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.69 48.0 3.35e-01 86.6% 22.1%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 51.0 4.82e-01 81.7% 89.1%
2lsgA00 1.20.58.1280 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DNA repair protein Rev1, C-terminal domain 0.68 59.0 5.66e-01 100.0% 87.6%
5c8aA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.67 54.0 5.49e-01 90.2% 100.0%
1nfvA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 58.0 4.47e-01 92.7% 78.1%
2np5D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.66 49.0 4.04e-01 81.7% 69.0%
2r6tB01 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.65 56.0 4.55e-01 100.0% 81.3%
4ezbA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.65 54.0 4.78e-01 90.2% 84.6%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 51.0 4.57e-01 86.6% 83.8%
4dlqA02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 56.0 5.35e-01 98.8% 97.9%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.64 51.0 4.50e-01 89.0% 88.2%
2i2oA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 55.0 4.19e-01 100.0% 64.5%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 50.0 4.63e-01 86.6% 91.6%
1gcvB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.64 48.0 4.15e-01 82.9% 61.0%
1a00B00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.64 49.0 4.09e-01 84.1% 55.5%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 49.0 3.71e-01 85.4% 46.2%
1s2xA00 1.20.190.30 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ 0.63 54.0 4.29e-01 97.6% 95.0%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.63 54.0 5.40e-01 98.8% 98.8%
2vxgA02 1.10.220.100 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › conserved c-terminal region of ge- 1 0.63 51.0 5.04e-01 87.8% 95.3%
3m6jA01 1.20.1260.40 Mainly Alpha › Up-down Bundle › Ferritin › 0.63 54.0 4.75e-01 92.7% 88.0%
5dllA05 1.25.50.10 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain 0.63 55.0 3.73e-01 98.8% 34.9%
2khqA01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.63 51.0 4.78e-01 90.2% 74.5%
2zcmA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 46.0 3.69e-01 81.7% 56.2%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 53.0 4.65e-01 93.9% 90.0%
5u56A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 47.0 4.23e-01 81.7% 78.6%
3qkyA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 53.0 3.81e-01 98.8% 36.7%
2kjgA00 1.20.120.970 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.60 44.0 4.15e-01 76.8% 98.0%
7qocA01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.60 51.0 3.94e-01 93.9% 45.5%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 48.0 4.98e-01 90.2% 94.7%
2dg8D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 44.0 3.57e-01 81.7% 57.8%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 51.0 4.63e-01 95.1% 85.8%
4houB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 42.0 2.97e-01 92.7% 24.8%
3ckyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.59 47.0 3.99e-01 85.4% 76.1%
4dllB02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.59 47.0 4.04e-01 85.4% 78.5%
2uyyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.59 47.0 4.10e-01 85.4% 82.9%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 46.0 4.33e-01 86.6% 98.0%
1vpdA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.59 46.0 4.00e-01 85.4% 77.9%
3sjrA00 1.10.132.90 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.59 48.0 4.21e-01 91.5% 92.1%
2gf2A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.58 46.0 3.93e-01 85.4% 82.8%
3w6zA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.58 46.0 4.06e-01 85.4% 84.3%
3g0oA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.58 46.0 4.07e-01 86.6% 85.1%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.57 44.0 4.01e-01 85.4% 90.5%
2dlaA01 1.20.930.50 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.57 45.0 3.67e-01 91.5% 45.0%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.57 48.0 4.01e-01 95.1% 77.6%
2ckwA04 1.20.960.20 Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › 0.57 46.0 4.24e-01 90.2% 73.8%
3pasA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 45.0 3.52e-01 92.7% 56.8%
2ew2A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.55 44.0 3.78e-01 89.0% 93.3%
5lb3B02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 48.0 3.53e-01 100.0% 77.2%
3sqiA01 1.10.150.540 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.55 45.0 4.33e-01 95.1% 78.8%
3kd4A02 3.10.620.30 Alpha Beta › Roll › C8orf32 fold › 0.54 38.0 3.12e-01 74.4% 69.4%
4hzuS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.54 45.0 3.71e-01 97.6% 54.9%
1f2eA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 44.0 4.09e-01 93.9% 89.6%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3748995 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.78 64.0 4.67e-01 89.0% 39.1%
3841683 109.3.1.163 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_4, Ank_5 0.75 66.0 4.10e-01 95.1% 21.4%
3671230 109.4.1.578 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3730 0.74 62.0 4.11e-01 93.9% 23.1%
3593444 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 61.0 4.47e-01 92.7% 44.1%
5008560 4995.1.1.1 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.71 59.0 5.50e-01 93.9% 77.1%
None — 0.70 57.0 5.04e-01 89.0% 65.0%
3678146 604.3.1.1 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.70 56.0 4.71e-01 86.6% 62.9%
3877040 1134.1.1.0 ↗ alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.69 50.0 5.26e-01 75.6% 86.7%
5076243 4995.1.1.1 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.68 57.0 5.63e-01 95.1% 91.1%
3714155 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 54.0 5.18e-01 86.6% 86.3%
3414736 109.4.1.393 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS1_RP2B-bd 0.67 56.0 3.67e-01 92.7% 22.2%
3510805 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 54.0 4.58e-01 95.1% 51.7%
3342220 109.4.1.1495 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26522 0.67 58.0 3.93e-01 100.0% 26.5%
3511386 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 58.0 3.30e-01 100.0% 13.2%
3273401 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 57.0 4.34e-01 100.0% 85.4%
3370265 604.3.1.1 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.66 48.0 4.17e-01 78.0% 58.5%
1019380 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.65 51.0 4.71e-01 85.4% 92.6%
3197170 109.4.1.70 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.65 53.0 4.10e-01 90.2% 47.9%
3240466 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 51.0 4.88e-01 85.4% 97.9%
5041952 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.65 57.0 4.87e-01 100.0% 93.3%
3225080 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.64 57.0 4.98e-01 100.0% 96.8%
3787731 109.4.1.273 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PI4KB-PIK1_PIK 0.64 57.0 4.92e-01 100.0% 64.6%
4467337 304.41.1.1 ↗ a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N 0.64 53.0 4.53e-01 93.9% 95.0%
5038736 621.1.1.0 ↗ alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.64 48.0 4.59e-01 79.3% 93.7%
3918080 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 50.0 4.76e-01 86.6% 95.0%
3512514 109.4.1.1286 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 0.63 51.0 3.49e-01 87.8% 26.2%
3398024 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.63 50.0 4.80e-01 86.6% 90.5%
3405975 633.21.1.42 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF4781 0.63 56.0 4.27e-01 96.3% 65.4%
4111537 633.23.1.32 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › CASP_dom 0.63 52.0 4.19e-01 91.5% 78.1%
4990303 304.41.1.1 ↗ a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N 0.63 51.0 4.26e-01 90.2% 93.1%
3314029 633.23.1.32 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › CASP_dom 0.62 52.0 4.16e-01 91.5% 76.7%
3212831 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.62 49.0 3.78e-01 85.4% 55.7%
3393821 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.61 51.0 4.11e-01 90.2% 85.8%
3755128 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.61 48.0 4.58e-01 86.6% 97.9%
5011123 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 48.0 4.45e-01 86.6% 81.0%
3913809 150.1.1.101 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › MARVEL 0.60 53.0 4.32e-01 96.3% 84.0%
3801688 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 49.0 4.56e-01 90.2% 91.4%
3708192 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 51.0 4.60e-01 98.8% 80.8%
3516305 109.4.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm 0.59 51.0 3.80e-01 100.0% 36.0%
3686783 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 45.0 4.24e-01 84.1% 89.5%
3728304 604.12.1.24 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6604 0.59 53.0 4.94e-01 97.6% 92.0%
3602354 1030.1.1.1 ↗ alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Csm2_III-A 0.59 44.0 3.94e-01 80.5% 100.0%
3518983 7015.1.1.0 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.59 52.0 4.32e-01 97.6% 90.7%
4520500 601.1.2.47 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › MARVEL 0.59 51.0 4.26e-01 96.3% 87.9%
3410900 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 45.0 3.88e-01 87.8% 66.2%
3715165 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 50.0 3.37e-01 100.0% 26.1%
None — 0.58 50.0 3.36e-01 100.0% 33.6%
3622530 109.4.1.59 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF383,DUF384 0.57 49.0 3.35e-01 100.0% 42.4%
4997741 1075.5.1.8 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.56 41.0 3.25e-01 80.5% 80.5%
3820263 7016.1.1.0 ↗ extended segments › Palmitoyltransferase DHHC C-terminal domain › Palmitoyltransferase DHHC C-terminal domain › Palmitoyltransferase DHHC C-terminal domain 0.55 47.0 3.95e-01 96.3% 92.4%
4683236 3455.1.1.0 ↗ alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors 0.54 44.0 4.28e-01 93.9% 87.4%
3642615 109.4.1.297 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_EMC2 0.54 43.0 3.72e-01 92.7% 54.8%
D4 medium residues 222-328
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF19528.5 best DUF6056 35.7 6.30e-09 98.1% 17.8%
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.71 54.0 5.51e-01 79.4% 100.0%
1sk7A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.70 54.0 4.43e-01 80.4% 100.0%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 55.0 5.04e-01 84.1% 69.0%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.68 54.0 4.91e-01 84.1% 65.7%
2oznB01 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.68 49.0 5.51e-01 78.5% 100.0%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.67 48.0 4.65e-01 73.8% 68.1%
7s0rB01 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.67 46.0 5.20e-01 78.5% 98.7%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 54.0 5.19e-01 91.6% 88.5%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 50.0 4.50e-01 84.1% 72.9%
1o3uA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.64 46.0 4.45e-01 74.8% 82.5%
1rp3G02 1.20.140.160 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain 0.64 46.0 4.24e-01 75.7% 69.7%
3bvxA02 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.64 51.0 5.06e-01 86.0% 85.6%
3a7kB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 52.0 3.98e-01 90.7% 68.6%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 50.0 4.88e-01 86.9% 90.7%
3mvuA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.62 46.0 3.65e-01 77.6% 98.7%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.62 51.0 4.53e-01 90.7% 93.6%
4fz4A00 1.20.140.130 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.60 48.0 4.26e-01 86.0% 89.0%
1dowA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 50.0 4.07e-01 91.6% 69.3%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.59 42.0 4.20e-01 85.0% 71.4%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 46.0 4.54e-01 88.8% 77.8%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.59 44.0 3.84e-01 82.2% 60.1%
3b5oA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.59 46.0 3.66e-01 85.0% 97.4%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 44.0 4.28e-01 82.2% 79.0%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.58 43.0 4.09e-01 78.5% 71.8%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.58 44.0 4.12e-01 82.2% 63.5%
3o3mB01 1.20.1270.370 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 38.0 3.88e-01 84.1% 68.9%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 46.0 4.42e-01 87.9% 77.4%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.57 44.0 3.09e-01 81.3% 60.8%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 44.0 4.34e-01 87.9% 84.2%
3i1aA03 1.20.58.840 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 42.0 4.17e-01 79.4% 80.2%
7cj3A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 49.0 3.71e-01 95.3% 71.3%
3ieeA02 1.20.58.820 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 0.56 38.0 3.90e-01 70.1% 71.8%
4r78A02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.56 41.0 3.42e-01 76.6% 76.4%
3rzeA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 43.0 3.29e-01 83.2% 97.0%
4djhA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 41.0 3.08e-01 77.6% 70.0%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.56 42.0 3.55e-01 82.2% 53.1%
2j9wB00 1.20.120.1130 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain 0.55 37.0 3.82e-01 80.4% 72.7%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 40.0 3.60e-01 81.3% 53.9%
3mvpA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 39.0 3.56e-01 75.7% 74.5%
2l6xA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 44.0 3.50e-01 90.7% 43.4%
8sbeA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.54 41.0 3.44e-01 82.2% 78.6%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.54 41.0 3.78e-01 82.2% 66.4%
1txuA01 1.10.246.120 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.52 33.0 3.47e-01 72.0% 70.2%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.51 39.0 3.74e-01 91.6% 72.4%
3geeA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.50 38.0 3.25e-01 78.5% 57.7%
ECOD (61)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3977366 3352.1.1.10 ↗ alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › DUF6056 0.94 91.0 5.95e-01 100.0% 30.1%
3979915 3352.1.1.10 ↗ alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › DUF6056 0.89 85.0 5.61e-01 100.0% 30.1%
3700727 601.29.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › TM1646-like › TM1646-like 0.75 56.0 5.20e-01 78.5% 74.1%
3591756 601.29.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › TM1646-like › TM1646-like 0.71 52.0 4.85e-01 77.6% 71.9%
3766796 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.68 54.0 4.93e-01 84.1% 80.0%
3732253 5001.1.1.85 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.67 54.0 4.08e-01 88.8% 47.0%
4034270 632.19.1.3 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 0.66 48.0 5.30e-01 86.0% 100.0%
5041273 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.66 50.0 5.06e-01 79.4% 87.6%
4648665 632.7.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.66 46.0 5.04e-01 79.4% 90.6%
5079638 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.66 53.0 5.52e-01 86.9% 96.0%
3616117 601.1.1.25 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C 0.66 46.0 4.49e-01 80.4% 65.0%
3573590 632.22.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.66 50.0 5.16e-01 81.3% 91.0%
3595261 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.65 46.0 4.97e-01 78.5% 87.8%
3299195 141.1.1.3 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.65 47.0 3.42e-01 75.7% 97.7%
2507424 6091.1.1.1 ↗ alpha bundles › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase › FIVAR 0.65 49.0 5.38e-01 79.4% 100.0%
4173817 632.22.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.64 51.0 4.51e-01 86.9% 94.5%
5047795 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.64 51.0 3.94e-01 84.1% 96.7%
1180303 632.19.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › RICH 0.64 47.0 5.14e-01 88.8% 100.0%
4367113 632.22.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.64 51.0 5.21e-01 86.9% 96.2%
4038171 4044.1.1.1 ↗ alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane 0.64 49.0 5.25e-01 86.0% 96.7%
4000012 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.64 47.0 3.43e-01 76.6% 38.0%
5054937 140.1.1.14 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e 0.64 45.0 4.02e-01 73.8% 65.8%
3513656 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.63 51.0 4.28e-01 89.7% 53.8%
3492730 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.63 53.0 3.73e-01 95.3% 86.3%
3171735 632.7.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.62 45.0 4.76e-01 80.4% 86.3%
3505840 1025.1.1.0 ↗ alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain 0.62 44.0 4.70e-01 72.9% 87.8%
3599480 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.60 47.0 3.69e-01 83.2% 51.6%
3222708 3343.1.1.2 ↗ alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal 0.59 52.0 3.29e-01 100.0% 56.8%
3227678 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.59 47.0 4.83e-01 86.9% 96.0%
3182665 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.59 44.0 4.60e-01 80.4% 93.7%
3948632 5050.1.1.10 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 0.58 44.0 3.43e-01 82.2% 38.4%
3770378 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.58 43.0 3.15e-01 79.4% 61.9%
3663121 5069.1.1.62 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Chloroplast_duf 0.57 44.0 4.50e-01 81.3% 82.9%
4027586 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 45.0 3.47e-01 83.2% 60.9%
5009775 601.33.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.56 40.0 4.23e-01 75.7% 84.2%
3865934 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.56 48.0 3.42e-01 95.3% 93.2%
5059791 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.56 42.0 4.29e-01 80.4% 83.8%
3304870 5059.1.1.24 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › PUNUT 0.56 45.0 3.27e-01 90.7% 53.3%
3271750 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.56 44.0 3.22e-01 86.9% 31.2%
3922833 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.55 43.0 3.20e-01 84.1% 95.3%
3309852 5050.1.1.57 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like, NFD4_C 0.55 44.0 3.11e-01 85.0% 87.5%
3623558 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.55 41.0 2.83e-01 79.4% 91.9%
5024782 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 43.0 3.66e-01 83.2% 71.4%
3950977 5058.1.1.9 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Colicin_V 0.55 43.0 3.80e-01 84.1% 78.7%
3448339 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.55 43.0 3.90e-01 84.1% 77.2%
3863240 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 41.0 3.31e-01 80.4% 44.1%
4027595 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 43.0 3.50e-01 86.9% 85.2%
3881033 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.54 42.0 3.25e-01 86.0% 43.8%
3743186 601.4.1.34 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › SHR3_chaperone 0.54 43.0 3.76e-01 85.0% 66.3%
4672624 601.25.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.53 41.0 3.44e-01 79.4% 59.0%
3786229 5050.1.1.15 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like 0.53 44.0 3.45e-01 86.9% 54.4%
3970466 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 41.0 3.37e-01 84.1% 72.9%
5045877 141.1.1.3 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.53 43.0 3.10e-01 89.7% 61.2%
4377286 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 41.0 3.34e-01 86.0% 44.1%
4467968 605.4.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.52 39.0 3.82e-01 86.9% 72.5%
3329547 604.6.1.22 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 0.52 36.0 3.65e-01 72.9% 75.5%
4977057 3960.1.1.0 ↗ alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain 0.52 39.0 3.83e-01 79.4% 74.8%
4995712 142.1.1.0 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.52 37.0 3.90e-01 82.2% 82.1%
3668973 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.52 38.0 3.86e-01 85.0% 77.3%
3225918 5001.1.1.106 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Str 0.51 44.0 3.22e-01 99.1% 44.9%
3932453 6155.1.1.1 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.50 39.0 3.88e-01 87.9% 76.5%