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MW302330.1__QTJ63025.1__X__00047

Bact-Vir

MW302330.1__QTJ63025.1__X__00047

Identity

Accession:
MW302330 ↗
Kingdom:
phage

Quality

82.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-75
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3vm9A02 6.10.140.2110 Special › Helix non-globular › Helix Hairpins › 0.85 58.0 6.56e-01 97.3% 93.0%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.79 58.0 5.63e-01 78.7% 75.3%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.78 58.0 3.97e-01 80.0% 25.2%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.76 53.0 5.17e-01 73.3% 67.1%
2zy9A03 1.10.357.20 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain 0.74 54.0 4.12e-01 77.3% 36.8%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.73 55.0 4.31e-01 80.0% 68.8%
2db7A01 6.10.250.980 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.71 48.0 5.47e-01 72.0% 100.0%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 45.0 4.07e-01 70.7% 47.6%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.69 52.0 4.17e-01 81.3% 43.5%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.68 49.0 4.92e-01 77.3% 77.0%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.67 50.0 4.84e-01 81.3% 70.6%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 45.0 3.75e-01 73.3% 74.5%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.65 44.0 4.08e-01 70.7% 86.5%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.64 44.0 4.20e-01 72.0% 80.5%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.63 49.0 5.17e-01 88.0% 98.5%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.62 45.0 3.72e-01 76.0% 51.1%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.62 49.0 3.19e-01 85.3% 50.6%
4q5qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 44.0 3.92e-01 84.0% 52.4%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 42.0 4.21e-01 70.7% 97.4%
2efjA01 1.10.1200.270 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Methyltransferase, alpha-helical capping domain 0.61 42.0 3.49e-01 94.7% 40.3%
1zhhB01 3.30.450.220 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › LuxQ periplasmic domain, N-terminal subdomain 0.60 45.0 3.59e-01 81.3% 94.3%
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 42.0 4.58e-01 76.0% 91.9%
7t7kA01 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.56 46.0 4.00e-01 92.0% 76.3%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.53 45.0 4.46e-01 93.3% 93.8%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.53 40.0 4.30e-01 89.3% 92.4%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3991853 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.86 69.0 6.03e-01 84.0% 61.9%
3970666 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.80 60.0 6.03e-01 80.0% 84.0%
3574632 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.78 57.0 6.08e-01 88.0% 89.2%
4610596 5043.1.1.0 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like 0.78 57.0 6.10e-01 77.3% 89.2%
3800210 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.78 55.0 5.87e-01 80.0% 86.2%
4933188 5069.1.3.1 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt 0.77 68.0 6.33e-01 98.7% 88.4%
5010020 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.75 65.0 5.61e-01 94.7% 70.4%
3317016 150.5.1.102 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PF28483 0.74 55.0 5.79e-01 80.0% 94.1%
5054424 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.74 54.0 5.32e-01 80.0% 72.5%
3278617 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.72 47.0 5.41e-01 76.0% 100.0%
4295625 5043.1.1.0 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like 0.72 53.0 5.83e-01 85.3% 100.0%
4588350 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.70 57.0 4.50e-01 88.0% 48.7%
4029754 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 52.0 5.05e-01 81.3% 72.9%
4507542 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.69 47.0 4.49e-01 72.0% 67.8%
5029642 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.67 52.0 4.83e-01 84.0% 71.6%
3435812 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.66 47.0 3.93e-01 73.3% 47.2%
4958384 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.65 50.0 4.75e-01 84.0% 73.3%
3709169 1008.1.1.29 alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › DGF-1_C 0.63 53.0 5.09e-01 100.0% 81.1%
3740547 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.62 43.0 3.76e-01 72.0% 57.3%
4077176 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.62 48.0 4.57e-01 85.3% 75.6%
4960850 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.61 42.0 4.55e-01 72.0% 88.3%
5031927 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.61 54.0 5.21e-01 98.7% 91.8%
4080125 616.1.1.45 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › MIS13 0.59 48.0 4.75e-01 100.0% 85.0%
4955309 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.59 41.0 4.05e-01 97.3% 67.5%
3534511 11.2.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.58 43.0 3.38e-01 80.0% 62.5%
5035107 3922.1.1.358 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF26119 0.57 45.0 3.91e-01 84.0% 85.1%
4029043 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.56 44.0 4.21e-01 97.3% 72.2%
3288637 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.56 45.0 4.52e-01 88.0% 89.3%
D2 high residues 470-583
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13559.12 best DUF4129 37.4 3.00e-09 58.8% 100.0%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wtyA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.73 58.0 5.79e-01 84.2% 98.3%
2q00B00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.70 56.0 5.48e-01 85.1% 95.1%
3pvuA02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.67 44.0 5.05e-01 86.0% 93.8%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.67 55.0 4.51e-01 89.5% 82.7%
3nynA03 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.66 43.0 5.01e-01 90.4% 93.8%
8jpdG01 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.65 47.0 4.34e-01 92.1% 59.3%
6lw5A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 53.0 3.96e-01 92.1% 82.8%
2uxwA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 42.0 4.07e-01 70.2% 70.0%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.61 42.0 3.23e-01 70.2% 77.6%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.61 51.0 5.03e-01 89.5% 94.1%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 42.0 3.88e-01 71.1% 58.0%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 41.0 4.27e-01 70.2% 76.6%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.60 49.0 4.72e-01 89.5% 78.2%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 47.0 4.69e-01 86.0% 96.6%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.59 49.0 4.61e-01 90.4% 85.4%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.57 40.0 3.49e-01 71.1% 81.1%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 40.0 3.70e-01 71.1% 59.2%
3d1uA03 1.20.1270.240 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.56 37.0 3.96e-01 84.2% 75.2%
1w9cA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.56 43.0 3.16e-01 81.6% 67.9%
2o8sA01 1.10.3700.10 Mainly Alpha › Orthogonal Bundle › AGR_C_984p-like › AGR C 984p-like 0.55 44.0 3.58e-01 86.8% 46.6%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.54 37.0 3.34e-01 70.2% 62.2%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.53 45.0 3.88e-01 93.0% 65.2%
2hgkA01 1.20.1440.40 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › YqcC-like 0.53 37.0 3.85e-01 71.1% 90.5%
3zh9B03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.53 39.0 3.82e-01 77.2% 97.6%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 41.0 3.57e-01 81.6% 97.1%
1dowA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 45.0 3.76e-01 95.6% 82.4%
3q23A08 1.20.140.110 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.52 36.0 3.29e-01 71.9% 59.1%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 41.0 4.07e-01 86.8% 90.1%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.52 34.0 3.57e-01 77.2% 72.6%
2w0gA00 1.20.58.610 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain 0.51 36.0 3.53e-01 78.9% 65.9%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4649219 601.7.1.34 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129 0.91 85.0 8.65e-01 97.4% 100.0%
4943902 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.83 69.0 6.80e-01 87.7% 90.8%
4203087 601.7.1.48 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PF29375 0.80 57.0 5.78e-01 73.7% 81.7%
4955523 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.71 57.0 5.70e-01 85.1% 92.2%
5054534 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.69 55.0 5.68e-01 84.2% 97.1%
3552346 196.1.1.1 alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS 0.68 48.0 4.01e-01 92.1% 43.7%
3618116 196.1.1.1 alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS 0.65 44.0 3.81e-01 92.1% 44.4%
3932077 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.64 53.0 4.56e-01 88.6% 73.7%
3274841 196.1.1.1 alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS 0.62 46.0 4.29e-01 92.1% 62.9%
3884704 196.1.1.1 alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS 0.61 43.0 3.82e-01 91.2% 49.4%
165282 601.29.1.1 alpha bundles › Four-helical up-and-down bundle › TM1646-like › TM1646-like › DUF327 0.61 51.0 5.03e-01 89.5% 94.1%
3239069 5001.1.1.25 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sru 0.60 50.0 3.69e-01 92.1% 79.0%
3923090 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.58 40.0 3.58e-01 71.1% 59.5%
3460193 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 46.0 4.67e-01 89.5% 86.1%
3841891 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.56 47.0 2.93e-01 93.0% 18.1%
3584217 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.56 39.0 3.93e-01 71.1% 74.8%
3766742 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.56 39.0 3.98e-01 71.9% 87.8%
4019714 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.56 38.0 3.77e-01 70.2% 65.8%
3208120 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.55 40.0 3.57e-01 73.7% 81.3%
1503824 604.24.1.1 alpha bundles › Spectrin repeat-like › Helical bundle domain in putative transcriptional regulator Jann_0659-related proteins › Helical bundle domain in putative transcriptional regulator Jann_0659-related proteins › PaaX_C 0.55 37.0 4.16e-01 71.9% 89.5%
5083298 4016.1.1.0 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.55 33.0 3.07e-01 100.0% 44.7%
3236489 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 45.0 4.26e-01 89.5% 85.9%
4563315 140.1.1.14 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e 0.54 33.0 3.06e-01 71.9% 46.7%
2545638 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.54 45.0 4.15e-01 91.2% 90.1%
3321745 601.1.1.105 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › RPW8 0.53 44.0 4.29e-01 90.4% 84.8%
3406984 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 38.0 3.18e-01 73.7% 74.9%
3974221 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.53 44.0 4.27e-01 93.9% 86.2%
4950911 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.52 36.0 3.32e-01 70.2% 54.5%
3490487 101.1.1.64 alpha arrays › HTH › HTH › Three-helical HTH › tRNA_bind_2 0.52 41.0 4.22e-01 87.7% 92.4%
4014114 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 42.0 3.17e-01 88.6% 58.9%
3981622 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 41.0 3.57e-01 87.7% 60.5%
4873484 150.2.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Cobalamin adenosyltransferase › Cobalamin adenosyltransferase › Cob_adeno_trans 0.51 41.0 3.95e-01 84.2% 89.0%
3470435 196.1.1.1 alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS 0.50 44.0 4.00e-01 98.2% 70.3%
3919852 5000.3.1.1 alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 0.50 38.0 3.26e-01 78.9% 82.2%
D3 medium residues 117-140_153-239_355-380
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7nitA06 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.53 41.0 3.81e-01 81.8% 90.7%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4608790 7072.1.1.0 beta sandwiches › N-terminal half of TgpA periplasmic domain › N-terminal half of TgpA periplasmic domain › N-terminal half of TgpA periplasmic domain 0.94 75.0 7.43e-01 81.0% 90.7%
4963198 7072.1.1.1 beta sandwiches › N-terminal half of TgpA periplasmic domain › N-terminal half of TgpA periplasmic domain › N-terminal half of TgpA periplasmic domain › TgpA_N 0.78 61.0 6.10e-01 81.0% 81.4%
5068538 7072.1.1.0 beta sandwiches › N-terminal half of TgpA periplasmic domain › N-terminal half of TgpA periplasmic domain › N-terminal half of TgpA periplasmic domain 0.77 60.0 6.08e-01 81.0% 89.6%
4001102 4111.1.1.3 a+b two layers › AF0104/ALDC/Ptd012-like › AF0104/ALDC/Ptd012-like › AF0104/ALDC/Ptd012-like › DUF1907 0.52 39.0 3.06e-01 78.1% 92.9%
3781272 10.32.1.204 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Rax2_2 0.51 39.0 3.48e-01 81.0% 94.5%
3282461 11.1.5.28 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › DUF1775 0.50 39.0 3.69e-01 81.0% 81.9%
D4 medium residues 141-152_240-354_381-412
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01841.26 best Transglut_core 72.5 4.70e-20 62.9% 99.1%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ex0B02 3.90.260.10 Alpha Beta › Alpha-Beta Complex › Coagulation Factor XIII; Chain A, domain 2 › Transglutaminase-like 0.79 66.0 5.11e-01 86.2% 73.6%
3isrA01 3.10.620.30 Alpha Beta › Roll › C8orf32 fold › 0.79 70.0 6.61e-01 92.5% 93.5%
3kd4A02 3.10.620.30 Alpha Beta › Roll › C8orf32 fold › 0.61 55.0 5.58e-01 96.2% 95.0%
1nklA00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.53 27.0 3.69e-01 90.6% 100.0%
1rl2A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 17.0 2.65e-01 86.8% 73.2%
ECOD (76)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4284097 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.95 83.0 8.22e-01 89.3% 100.0%
4963199 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.93 69.0 6.82e-01 75.5% 81.8%
2504478 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.88 68.0 7.04e-01 79.2% 95.4%
5068539 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.86 75.0 7.20e-01 89.3% 100.0%
5077838 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.85 75.0 7.29e-01 90.6% 98.8%
4975231 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.85 75.0 6.99e-01 91.8% 97.4%
5073453 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.84 71.0 7.02e-01 86.8% 99.4%
4983620 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.84 74.0 7.46e-01 91.8% 100.0%
4944381 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.84 62.0 6.30e-01 75.5% 100.0%
4978195 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.83 72.0 6.83e-01 89.9% 100.0%
4970894 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.83 77.0 7.15e-01 95.6% 97.9%
5052982 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.83 64.0 6.31e-01 79.9% 100.0%
4948578 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.83 71.0 7.41e-01 88.1% 99.3%
5069346 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.83 64.0 5.75e-01 78.6% 79.0%
4950254 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.82 69.0 6.32e-01 86.8% 84.0%
5026689 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.82 72.0 6.74e-01 91.2% 94.2%
5062591 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.82 73.0 5.60e-01 93.1% 77.6%
5001455 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.82 72.0 6.56e-01 91.2% 82.5%
5081248 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.81 68.0 7.02e-01 91.2% 91.3%
4954944 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.81 62.0 6.34e-01 78.6% 91.6%
5055945 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.80 61.0 6.39e-01 77.4% 88.3%
3952751 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.80 70.0 6.57e-01 91.2% 84.7%
4948573 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.80 72.0 5.65e-01 93.7% 65.2%
5059308 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.80 71.0 6.00e-01 92.5% 92.2%
5049075 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.80 67.0 6.40e-01 86.8% 94.4%
4974842 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.80 71.0 6.15e-01 92.5% 87.4%
4941017 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.79 66.0 6.86e-01 86.2% 94.0%
4953249 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.79 64.0 6.49e-01 82.4% 91.0%
5064712 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.79 65.0 6.26e-01 84.3% 86.3%
5029143 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.79 67.0 6.70e-01 86.8% 91.9%
3165617 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.79 67.0 6.15e-01 88.7% 94.0%
4945365 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.78 69.0 6.83e-01 91.2% 89.7%
4978783 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.78 65.0 6.69e-01 84.9% 93.3%
4980439 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.78 69.0 6.40e-01 91.2% 92.1%
4992782 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.78 65.0 6.33e-01 85.5% 95.3%
4977424 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.78 68.0 6.86e-01 91.2% 91.3%
5064595 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.78 68.0 5.96e-01 91.2% 65.5%
5066225 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.77 68.0 6.72e-01 91.2% 89.7%
5055414 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.77 68.0 6.18e-01 91.8% 87.8%
4969783 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.77 69.0 5.38e-01 92.5% 70.4%
5082717 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.77 68.0 6.17e-01 92.5% 98.5%
3250689 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.77 66.0 6.34e-01 89.9% 90.0%
4959664 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.77 68.0 5.99e-01 92.5% 93.2%
5069875 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.74 68.0 5.62e-01 94.3% 80.4%
4942072 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.74 59.0 5.74e-01 98.7% 76.5%
5012873 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.74 62.0 5.65e-01 88.1% 79.5%
3816635 219.1.1.79 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core2 0.72 52.0 5.37e-01 73.6% 92.0%
5060170 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.71 67.0 5.22e-01 98.7% 71.1%
5077834 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.71 64.0 5.17e-01 93.7% 61.8%
5062328 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.70 65.0 5.28e-01 98.7% 77.0%
5029334 219.1.1.76 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF553 0.70 56.0 5.51e-01 98.1% 79.2%
146744 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.69 55.0 5.59e-01 95.6% 83.5%
5078205 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.68 60.0 5.83e-01 98.7% 85.3%
5022074 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.67 60.0 5.47e-01 92.5% 86.5%
3513887 219.1.1.97 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › CEPT76_peptidase 0.66 53.0 4.90e-01 96.9% 66.0%
5033329 219.1.1.76 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF553 0.66 59.0 5.70e-01 96.2% 84.6%
4217957 219.1.1.79 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core2 0.66 55.0 5.50e-01 98.7% 84.8%
4952203 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.65 60.0 5.17e-01 96.2% 80.0%
4192402 219.1.1.79 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core2 0.65 55.0 5.46e-01 98.7% 85.5%
3170800 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.65 57.0 4.92e-01 91.8% 74.5%
5066083 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.65 60.0 5.37e-01 96.2% 73.2%
4955468 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.65 59.0 5.56e-01 96.2% 92.6%
3721511 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.65 57.0 5.02e-01 92.5% 93.8%
3639695 219.1.1.79 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core2 0.64 54.0 4.63e-01 98.7% 57.6%
4928444 219.1.1.79 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core2 0.64 59.0 5.70e-01 96.9% 89.1%
4955823 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.64 59.0 4.93e-01 96.2% 76.8%
4003142 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.64 53.0 4.47e-01 86.2% 94.4%
3403157 219.1.1.97 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › CEPT76_peptidase 0.63 51.0 4.45e-01 98.1% 57.8%
3347055 219.1.1.111 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core, Rad4 0.63 55.0 4.55e-01 98.1% 54.3%
5064007 219.1.1.76 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF553 0.63 56.0 5.39e-01 96.9% 82.8%
4951884 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.62 59.0 5.53e-01 98.1% 89.2%
4941446 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.62 57.0 5.26e-01 98.1% 85.0%
3685551 219.1.1.79 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core2 0.61 53.0 4.91e-01 96.9% 73.0%
3491413 219.1.1.97 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › CEPT76_peptidase 0.56 49.0 4.13e-01 98.7% 57.6%
4946417 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 36.0 3.20e-01 84.3% 48.6%
4967165 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.50 24.0 3.29e-01 89.9% 95.7%