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MW349128.1__QQO92475.1__CPT_Machias_085__00081

Bact-Vir

MW349128.1__QQO92475.1__CPT_Machias_085__00081

Identity

Accession:
MW349128 ↗
Kingdom:
phage

Quality

83.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 30-90_753-895_927-963
PDB
CATH (42)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3foaB01 3.40.50.11780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.78 68.0 7.19e-01 90.0% 98.2%
4q6bA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.71 36.0 4.75e-01 97.9% 86.6%
4rkrD02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.71 38.0 4.86e-01 97.5% 86.8%
2i2cA01 3.40.50.10330 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Probable inorganic polyphosphate/atp-NAD kinase; domain 1 0.70 33.0 4.56e-01 97.9% 86.4%
1efaA03 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 37.0 4.72e-01 97.5% 86.0%
3h5lA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 41.0 4.91e-01 100.0% 86.1%
3kjxA03 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 37.0 4.68e-01 97.9% 87.2%
5yszA03 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 36.0 4.62e-01 97.5% 86.3%
5ufhA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.68 40.0 4.84e-01 97.9% 87.7%
4rxmA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.68 37.0 4.83e-01 87.1% 96.1%
1jr2A01 3.40.50.10090 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.67 35.0 4.75e-01 81.7% 99.2%
3eafA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.66 39.0 4.49e-01 97.5% 78.0%
1abeA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.66 38.0 4.80e-01 87.6% 96.4%
2qv7A01 3.40.50.10330 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Probable inorganic polyphosphate/atp-NAD kinase; domain 1 0.65 38.0 4.78e-01 95.0% 95.2%
2yvaA00 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.63 39.0 4.38e-01 83.8% 76.7%
3c3jA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.62 37.0 4.13e-01 90.5% 72.7%
2q9uA02 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.61 38.0 4.73e-01 82.2% 100.0%
5irnA02 3.80.10.10 Alpha Beta › Alpha-Beta Horseshoe › Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) › Ribonuclease Inhibitor 0.60 25.0 3.99e-01 91.7% 100.0%
3oy2A01 3.40.50.11930 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 39.0 4.76e-01 87.6% 98.8%
3fmgA01 3.40.50.11130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoprotein VP7, domain 1 0.60 37.0 4.56e-01 100.0% 98.0%
2dplA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.60 29.0 3.49e-01 92.1% 66.5%
3g5jA00 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.59 31.0 3.99e-01 90.0% 89.2%
2hoqA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.58 37.0 4.47e-01 100.0% 96.2%
2b7nA02 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.57 28.0 3.53e-01 75.9% 74.0%
1f8uA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 48.0 3.71e-01 88.4% 90.8%
3r7wA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 42.0 4.70e-01 82.6% 98.4%
4cooB01 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 40.0 4.27e-01 78.0% 82.0%
2veoA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 47.0 4.25e-01 88.4% 80.8%
1fuyB01 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 34.0 4.06e-01 80.9% 87.2%
6eudA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 29.0 3.44e-01 77.6% 70.0%
2waaA02 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.54 44.0 4.69e-01 99.6% 97.6%
2f48A01 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 42.0 4.03e-01 94.2% 69.8%
1bwpA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.53 43.0 4.58e-01 97.5% 96.2%
4s1hA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.53 46.0 4.31e-01 91.3% 95.8%
2w9xA02 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.52 45.0 4.65e-01 100.0% 96.9%
4rxuA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 37.0 4.09e-01 95.0% 89.6%
1orrC00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 47.0 4.21e-01 97.5% 93.1%
3up8A00 3.20.20.100 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain 0.51 33.0 3.16e-01 84.2% 54.4%
5hc2B00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 45.0 4.01e-01 94.6% 84.2%
2v82A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 32.0 3.41e-01 92.5% 70.2%
1a5aA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 36.0 3.61e-01 92.5% 68.6%
2ckrA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.51 41.0 3.77e-01 92.5% 65.9%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4995822 2499.2.1.1 a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1 0.85 79.0 7.72e-01 95.0% 95.3%
3978226 2499.2.1.1 a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1 0.83 76.0 7.13e-01 94.2% 92.1%
5004680 2499.2.1.1 a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1 0.80 73.0 6.97e-01 94.2% 92.0%
3944167 2499.2.1.2 a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1,Gp18_domIII_N 0.78 71.0 6.82e-01 93.8% 91.9%
4888782 2499.2.1.2 a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1,Gp18_domIII_N 0.78 71.0 6.73e-01 94.2% 95.7%
1518917 2499.2.1.2 a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › Phage_sheath_1,Gp18_domIII_N 0.78 71.0 6.73e-01 94.2% 91.2%
2468538 2499.2.1.0 a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 0.77 70.0 6.89e-01 95.0% 98.4%
4889792 2499.2.1.0 a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 0.73 64.0 6.72e-01 95.4% 99.1%
4928374 2005.1.1.4 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Asn_synthase 0.66 31.0 3.86e-01 91.3% 68.8%
3948874 2499.2.1.6 a/b three-layered sandwiches › Subtilisin-like › Domain III of tail sheath protein Gp18 › Domain III of tail sheath protein Gp18 › DUF3383 0.65 57.0 5.75e-01 92.9% 91.7%
2601560 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.60 39.0 4.67e-01 87.6% 94.6%
3964279 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.60 39.0 4.76e-01 90.0% 98.8%
5079738 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.56 46.0 4.85e-01 100.0% 95.8%
4479997 7579.1.1.2 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Lipase 0.56 50.0 4.50e-01 95.4% 86.5%
4033280 2002.1.1.38 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TAL_FSA 0.55 35.0 3.76e-01 91.3% 70.5%
3408206 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.55 37.0 4.33e-01 82.6% 100.0%
3449559 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 39.0 4.40e-01 99.6% 96.2%
3398275 2007.5.1.8 a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › Lipase_GDSL_2 0.53 44.0 4.57e-01 97.9% 92.4%
3813073 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.53 40.0 4.43e-01 100.0% 96.8%
3896215 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.53 38.0 4.24e-01 100.0% 92.1%
4969646 2484.1.1.338 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › baeRF_family10 0.53 30.0 3.80e-01 100.0% 94.8%
3298888 2005.1.1.23 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA_Me_trans 0.53 33.0 3.57e-01 81.3% 70.5%
4128176 6108.1.1.0 alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins 0.53 42.0 3.14e-01 84.2% 41.1%
3612556 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.51 46.0 3.89e-01 97.1% 79.0%
3190105 7564.1.1.1 a/b three-layered sandwiches › Homo-oligomeric flavin-containing Cys decarboxylases, HFCD › Homo-oligomeric flavin-containing Cys decarboxylases, HFCD › Homo-oligomeric flavin-containing Cys decarboxylases, HFCD › Flavoprotein 0.51 42.0 4.36e-01 84.2% 97.7%
3598702 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.51 33.0 3.77e-01 99.2% 86.9%
3590685 7579.1.1.96 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9, Abhydrolase_1 0.51 45.0 4.52e-01 95.9% 97.6%
3711703 7579.1.1.44 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_6 0.51 46.0 3.84e-01 97.1% 79.0%
4318702 7512.1.1.38 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › EryCIII-like_N 0.50 41.0 4.39e-01 100.0% 99.5%
D2 high residues 973-1034
PDB
CATH (48)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6fgjA01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.73 57.0 4.37e-01 87.1% 53.3%
2mq8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.71 54.0 4.49e-01 93.5% 46.4%
1ylxA00 3.30.70.1480 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GK1464-like 0.71 51.0 4.41e-01 93.5% 48.5%
1xdxA01 3.30.1140.40 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 0.71 63.0 5.37e-01 100.0% 90.0%
3og5A01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.69 60.0 5.41e-01 100.0% 70.6%
2x3gA00 3.30.70.1910 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 50.0 4.06e-01 93.5% 40.5%
2oplA01 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.68 52.0 3.84e-01 85.5% 38.4%
2qdfA02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.68 59.0 5.38e-01 100.0% 73.5%
5uayA02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.67 55.0 5.01e-01 96.8% 67.5%
6s2vC02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.67 52.0 4.01e-01 85.5% 44.1%
3w9iA06 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.67 55.0 4.68e-01 98.4% 55.9%
1gpmA03 3.30.300.10 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.67 51.0 4.22e-01 82.3% 66.7%
4k3bA04 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.65 52.0 4.90e-01 98.4% 73.1%
1q2lA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.65 52.0 3.58e-01 91.9% 27.3%
2pn2A00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.64 49.0 3.88e-01 85.5% 43.1%
4oycB00 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.62 45.0 4.12e-01 83.9% 56.2%
3anoA00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.61 52.0 3.96e-01 100.0% 57.0%
6jp6D01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 51.0 3.56e-01 100.0% 37.1%
4k3cA01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.60 47.0 4.46e-01 100.0% 72.0%
1cx8A01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.59 49.0 3.27e-01 100.0% 91.9%
1emsA02 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.59 49.0 4.04e-01 100.0% 66.9%
6x6aA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 45.0 2.99e-01 85.5% 32.0%
1bdfA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.58 50.0 4.24e-01 98.4% 69.8%
2nvmA00 3.30.310.110 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › XisI-like 0.58 41.0 3.51e-01 87.1% 44.2%
3l7xA00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.58 49.0 3.77e-01 100.0% 51.6%
4ushA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 44.0 3.79e-01 83.9% 64.1%
2od6C00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 45.0 3.87e-01 91.9% 51.4%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.58 48.0 3.96e-01 98.4% 50.0%
4qglA00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.56 46.0 3.47e-01 96.8% 73.0%
5suvC00 3.90.470.20 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain 0.56 47.0 3.86e-01 98.4% 94.4%
8c46A01 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 46.0 3.89e-01 98.4% 63.2%
2ltsA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.55 39.0 3.61e-01 98.4% 57.0%
2xefA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.54 44.0 2.92e-01 100.0% 19.1%
1rjjA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 44.0 3.79e-01 98.4% 54.1%
1av5A00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.54 44.0 3.82e-01 100.0% 72.6%
1whnA01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.54 40.0 3.49e-01 100.0% 50.5%
1a3wA01 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.54 45.0 3.43e-01 95.2% 49.0%
1sqhA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.54 39.0 2.88e-01 74.2% 75.3%
2ab5B01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.54 36.0 2.98e-01 72.6% 35.2%
1a49A01 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.52 44.0 3.24e-01 95.2% 43.2%
2cz4A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 42.0 3.61e-01 88.7% 73.7%
1o51A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 38.0 3.45e-01 98.4% 56.2%
3bb5A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 39.0 3.51e-01 98.4% 55.3%
3b8pA00 3.30.1890.10 Alpha Beta › 2-Layer Sandwich › Bacterial polysaccharide co-polymerase-like › FepE-like 0.51 42.0 3.00e-01 93.5% 35.7%
7o4xA01 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 39.0 3.40e-01 85.5% 82.8%
3syyA00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.51 40.0 3.00e-01 96.8% 30.4%
4bhqA00 3.30.70.2830 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 43.0 3.68e-01 100.0% 82.6%
3fvyA03 3.30.70.2600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 34.0 3.25e-01 82.3% 58.7%
ECOD (57)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4957559 283.2.1.2 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › Phage_sheath_1C 0.93 87.0 7.25e-01 100.0% 70.0%
3980756 283.2.1.2 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › Phage_sheath_1C 0.88 81.0 6.66e-01 100.0% 61.9%
3949098 283.2.1.2 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › Phage_sheath_1C 0.86 78.0 6.36e-01 100.0% 59.1%
4433785 283.2.1.4 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › GP46 0.84 73.0 5.67e-01 100.0% 45.4%
1518918 283.2.1.2 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › Phage_sheath_1C 0.79 69.0 5.73e-01 100.0% 58.0%
3859320 864.1.1.2 a+b two layers › DLC › DLC › DLC › Tctex-1 0.73 64.0 5.21e-01 100.0% 77.1%
3530260 864.1.1.2 a+b two layers › DLC › DLC › DLC › Tctex-1 0.72 63.0 5.31e-01 100.0% 83.3%
4972328 512.1.1.1 a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st 0.72 47.0 4.49e-01 82.3% 56.0%
5027827 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.71 54.0 4.90e-01 98.4% 61.2%
3385833 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.68 58.0 3.66e-01 100.0% 34.0%
3484890 3121.1.1.0 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.68 53.0 4.70e-01 100.0% 57.9%
4898995 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.66 47.0 4.24e-01 93.5% 53.3%
5073695 512.1.1.1 a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st 0.66 49.0 4.26e-01 82.3% 87.0%
4443601 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.65 47.0 4.39e-01 98.4% 58.8%
3963889 3121.1.1.4 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA_TamA_1 0.65 55.0 5.08e-01 100.0% 75.0%
3488653 273.1.1.1 a+b three layers › PR-1-like › PR-1-like › PR-1-like › CAP 0.64 49.0 3.74e-01 85.5% 96.8%
4016124 192.29.1.148 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF3433 0.64 53.0 3.84e-01 93.5% 91.1%
4594258 3281.1.1.2 alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M,Proton_antipo_N 0.63 55.0 3.17e-01 100.0% 77.4%
3472642 3937.1.1.2 alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin 0.62 44.0 2.70e-01 74.2% 72.6%
3839149 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.62 51.0 4.70e-01 100.0% 70.6%
3422343 325.1.2.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Molybdopterin synthase subunit MoaE › MoaE 0.61 46.0 4.33e-01 85.5% 65.0%
4459698 302.1.1.1 a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C 0.61 46.0 4.42e-01 95.2% 70.7%
3952115 312.1.1.2 a+b three layers › HIT-like › HIT-related › HIT-related › HIT 0.61 53.0 3.88e-01 100.0% 51.4%
3950071 312.1.1.2 a+b three layers › HIT-like › HIT-related › HIT-related › HIT 0.61 52.0 3.83e-01 100.0% 50.0%
4881206 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.60 52.0 4.74e-01 100.0% 72.9%
5045778 312.1.1.1 a+b three layers › HIT-like › HIT-related › HIT-related › GalP_UDP_transf 0.60 52.0 3.99e-01 100.0% 68.7%
4183861 7573.1.1.4 a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › UPRTase 0.60 43.0 2.81e-01 74.2% 75.9%
4145584 3016.1.1.11 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › SelA 0.59 47.0 3.99e-01 91.9% 52.4%
4971261 312.1.1.2 a+b three layers › HIT-like › HIT-related › HIT-related › HIT 0.59 52.0 3.96e-01 100.0% 60.0%
4336680 3016.1.1.11 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › SelA 0.59 47.0 3.90e-01 91.9% 50.8%
4429890 3016.1.1.11 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › SelA 0.59 47.0 3.99e-01 93.5% 53.9%
4009799 274.1.1.4 a+b two layers › Pili subunits › Pili subunits › Pili subunits › T2SSI 0.59 41.0 3.56e-01 100.0% 44.8%
None 0.59 48.0 3.61e-01 98.4% 72.0%
4252594 10.12.1.15 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › ARD 0.58 48.0 3.61e-01 96.8% 72.6%
3597539 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 48.0 3.12e-01 100.0% 45.0%
None 0.58 47.0 3.58e-01 98.4% 73.1%
4029177 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.58 44.0 3.46e-01 87.1% 37.7%
4679984 10.12.1.15 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › ARD 0.58 47.0 3.60e-01 98.4% 74.1%
4525796 3351.1.1.1 a/b three-layered sandwiches › Atg7 N-terminal domain-like › N-terminal domain in E1 enzyme Atg7 › N-terminal domain in E1 enzyme Atg7 › ATG7_N 0.57 39.0 2.99e-01 83.9% 30.6%
4949163 312.1.1.2 a+b three layers › HIT-like › HIT-related › HIT-related › HIT 0.57 46.0 4.35e-01 98.4% 100.0%
5080980 330.2.1.1 a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › Ribosomal_S30AE 0.57 43.0 3.66e-01 85.5% 52.7%
4991693 312.1.1.2 a+b three layers › HIT-like › HIT-related › HIT-related › HIT 0.56 47.0 3.66e-01 100.0% 58.1%
3395555 2008.1.1.50 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YqaJ 0.56 44.0 2.92e-01 85.5% 22.1%
3707374 109.4.1.1341 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG3_N, COG3_C 0.56 47.0 2.80e-01 98.4% 29.2%
4507117 7581.1.1.10 a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › SpoVAD 0.56 47.0 3.66e-01 100.0% 93.3%
4978850 304.134.1.0 a+b two layers › Alpha-beta plaits › MJ1480-like › MJ1480-like 0.55 40.0 3.67e-01 98.4% 56.7%
4336686 314.1.1.11 a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA_synthFbeta 0.54 46.0 3.27e-01 100.0% 90.7%
3604508 304.8.1.4 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.54 37.0 3.41e-01 98.4% 52.2%
5001925 2008.1.1.108 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF234 0.54 41.0 3.20e-01 87.1% 84.0%
4933736 2008.1.1.223 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF3782 0.53 40.0 2.87e-01 83.9% 35.4%
3937002 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.52 42.0 2.79e-01 100.0% 36.2%
3684903 10.12.1.6 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › AIM24 0.52 38.0 2.65e-01 79.0% 36.8%
5078518 2008.1.1.220 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_10 0.51 39.0 3.33e-01 85.5% 62.7%
3200673 616.1.1.0 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.51 42.0 3.81e-01 100.0% 98.9%
4015832 230.1.1.0 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like 0.50 41.0 3.63e-01 100.0% 94.3%
1281164 868.1.1.5 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › Med18 0.50 37.0 3.34e-01 80.6% 85.6%
None 0.50 41.0 2.74e-01 100.0% 78.8%
D3 medium residues 91-184_244-279_738-752
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2yjlA00 2.60.40.2990 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 31.0 3.57e-01 77.9% 67.6%
1se8A02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.57 29.0 3.21e-01 93.8% 59.5%
3hvnA02 3.30.1040.20 Alpha Beta › 2-Layer Sandwich › Carboxypeptidase Inhibitor; Chain A › 0.56 18.0 2.76e-01 91.7% 66.0%
1g0dA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 28.0 3.26e-01 80.0% 70.1%
2q7nA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 31.0 3.52e-01 79.3% 72.7%
1fm2B03 2.30.120.10 Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region 0.53 21.0 2.95e-01 89.7% 74.2%
1mkfA02 2.60.40.1340 Mainly Beta › Sandwich › Immunoglobulin-like › Chemokine-binding protein M3-like 0.52 34.0 3.25e-01 86.2% 56.4%
2zaiA04 2.60.40.3030 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 33.0 3.46e-01 99.3% 70.5%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3212628 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.54 34.0 3.62e-01 76.6% 71.2%
4926859 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 29.0 3.19e-01 78.6% 64.2%
4024291 11.1.1.105 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Coatamer_beta_C 0.52 28.0 3.01e-01 79.3% 56.9%
3444078 221.1.1.82 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PADRE 0.51 26.0 2.98e-01 90.3% 63.6%
5001137 821.1.1.4 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › DUF123 0.51 38.0 3.89e-01 77.2% 100.0%
3631162 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.50 35.0 3.45e-01 77.2% 64.4%
5040537 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.50 27.0 3.04e-01 76.6% 66.4%
4979774 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.50 27.0 3.10e-01 78.6% 69.5%
D4 medium residues 334-386_458-528_670-737
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2x0cA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.62 48.0 4.95e-01 78.6% 95.5%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 40.0 4.62e-01 85.9% 89.4%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.58 47.0 4.54e-01 85.4% 83.8%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 42.0 4.80e-01 94.3% 100.0%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.57 41.0 4.24e-01 100.0% 76.6%
1jmwA00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.55 40.0 4.61e-01 99.0% 99.3%
1io1A01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.55 42.0 4.50e-01 100.0% 91.1%
1wp1B01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.54 39.0 3.15e-01 72.9% 96.2%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.54 39.0 3.92e-01 77.1% 72.0%
7nmqA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.52 48.0 3.84e-01 96.4% 86.3%
5ziyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.52 42.0 4.24e-01 100.0% 85.1%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3534741 192.8.1.276 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Rad50_zn_hook 0.67 33.0 2.28e-01 100.0% 14.5%
4979521 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.61 37.0 3.95e-01 93.2% 67.1%
4995044 1076.1.1.0 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related 0.59 44.0 4.27e-01 77.1% 74.5%
4990026 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.59 46.0 4.62e-01 81.2% 86.5%
4992416 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.59 43.0 4.14e-01 97.9% 65.6%
4999398 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.59 45.0 4.12e-01 79.7% 65.9%
4997682 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.58 46.0 4.41e-01 80.7% 79.1%
3916828 3684.1.1.27 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › ApoL 0.58 41.0 3.99e-01 71.4% 98.6%
5028176 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.58 45.0 3.94e-01 79.2% 61.8%
4932476 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.58 46.0 4.50e-01 82.8% 83.8%
4931937 3755.4.1.66 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › MCPsignal 0.58 29.0 2.39e-01 100.0% 27.2%
3212808 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.58 43.0 4.83e-01 100.0% 99.3%
3587915 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.57 44.0 4.30e-01 79.2% 78.1%
3685912 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.57 32.0 3.70e-01 80.2% 72.9%
5019371 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.57 44.0 3.95e-01 79.2% 63.0%
4055484 1075.5.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.57 44.0 3.73e-01 80.2% 57.1%
5043061 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.57 47.0 4.47e-01 87.0% 81.4%
4407105 1075.5.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.55 43.0 3.88e-01 80.2% 68.8%
5064040 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 29.0 2.88e-01 100.0% 47.3%
5058663 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 44.0 4.21e-01 86.5% 81.4%
5081835 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.53 41.0 4.09e-01 79.7% 78.0%
3962919 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.53 48.0 4.09e-01 97.9% 88.7%
5062035 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.53 38.0 3.80e-01 99.5% 70.0%
3477083 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 47.0 3.65e-01 100.0% 84.0%
4992579 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.52 37.0 3.76e-01 73.4% 95.4%
3859555 601.19.1.1 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein 0.51 39.0 4.01e-01 84.9% 82.8%
3403588 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.51 41.0 3.74e-01 84.4% 95.8%
3769992 5001.1.1.9 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TAS2R 0.51 38.0 3.28e-01 77.6% 56.4%
4978786 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 36.0 2.50e-01 70.3% 90.6%
3211056 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.51 30.0 3.18e-01 83.3% 63.5%
D5 medium residues 387-457_589-611
PDB
D6 medium residues 529-588_612-669
PDB
Domain cluster: representative
CATH (79)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.77 71.0 5.73e-01 100.0% 67.7%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.77 58.0 6.25e-01 99.2% 94.0%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.75 70.0 6.62e-01 100.0% 87.6%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 69.0 6.60e-01 100.0% 92.5%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 55.0 5.00e-01 75.4% 94.0%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.74 53.0 5.38e-01 74.6% 85.6%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.74 66.0 5.72e-01 99.2% 74.5%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.73 65.0 6.29e-01 98.3% 86.5%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 65.0 6.53e-01 95.8% 100.0%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 67.0 6.51e-01 100.0% 93.8%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.73 57.0 4.39e-01 83.1% 86.9%
1w33A00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.73 52.0 4.53e-01 74.6% 82.3%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.73 66.0 5.77e-01 100.0% 75.3%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.72 65.0 6.30e-01 97.5% 88.5%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.72 61.0 6.15e-01 100.0% 92.4%
3am6A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.72 66.0 5.31e-01 100.0% 80.8%
4im0A04 1.20.1270.420 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.72 53.0 4.16e-01 76.3% 80.7%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.72 65.0 5.53e-01 100.0% 72.3%
6gyhA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.72 66.0 5.29e-01 100.0% 82.7%
4nqfA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.71 65.0 6.07e-01 100.0% 95.2%
2rfqC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 52.0 4.51e-01 76.3% 68.0%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.70 61.0 6.23e-01 97.5% 98.2%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.70 61.0 6.18e-01 100.0% 95.8%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.69 63.0 6.16e-01 100.0% 90.6%
2lquA01 1.20.1420.40 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein 0.69 53.0 4.84e-01 100.0% 61.7%
1st6A01 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.69 62.0 4.83e-01 100.0% 50.2%
1wolA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 59.0 5.87e-01 93.2% 99.2%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.68 60.0 6.08e-01 99.2% 97.4%
1dowA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 59.0 4.94e-01 96.6% 59.0%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.67 43.0 5.12e-01 75.4% 100.0%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 47.0 4.71e-01 74.6% 70.8%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 59.0 5.83e-01 96.6% 99.2%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.67 47.0 4.78e-01 74.6% 74.6%
1b68A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.66 57.0 5.41e-01 94.9% 100.0%
3rvyA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.66 55.0 5.64e-01 96.6% 94.7%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.66 50.0 5.37e-01 79.7% 99.0%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.65 58.0 5.28e-01 100.0% 73.9%
7tj9A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.65 53.0 5.59e-01 94.9% 99.1%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 47.0 4.06e-01 75.4% 91.5%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 56.0 5.60e-01 94.9% 96.7%
4i1mB01 1.20.120.1700 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.63 53.0 5.15e-01 90.7% 92.2%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.63 54.0 4.02e-01 95.8% 86.2%
2d4xA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.63 57.0 4.70e-01 100.0% 84.1%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.63 57.0 4.91e-01 100.0% 65.2%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 54.0 4.05e-01 91.5% 77.1%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 47.0 4.08e-01 78.8% 76.5%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.62 51.0 4.73e-01 87.3% 77.7%
5ziyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.62 54.0 4.69e-01 100.0% 77.8%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.62 55.0 4.50e-01 100.0% 64.0%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.61 55.0 5.46e-01 97.5% 99.2%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.59 53.0 5.30e-01 100.0% 99.2%
3v5uA02 1.20.1420.30 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › NCX, central ion-binding region 0.58 48.0 3.98e-01 91.5% 59.3%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 40.0 4.27e-01 70.3% 89.2%
3swhA01 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.58 40.0 3.61e-01 70.3% 70.3%
2q24A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 43.0 3.80e-01 78.8% 75.7%
1orsC00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.57 49.0 4.78e-01 98.3% 94.7%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.57 40.0 4.14e-01 72.0% 89.9%
4f4cA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.57 50.0 3.14e-01 100.0% 72.3%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.56 41.0 4.56e-01 81.4% 98.9%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.56 50.0 4.70e-01 100.0% 92.5%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.55 41.0 3.68e-01 77.1% 76.2%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.55 41.0 3.81e-01 78.0% 65.8%
2iakA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 42.0 3.54e-01 78.8% 52.6%
1uddA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.55 46.0 3.93e-01 97.5% 83.7%
4abnA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 40.0 3.08e-01 96.6% 33.0%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.54 38.0 3.94e-01 71.2% 88.8%
4bejB02 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.54 47.0 3.93e-01 100.0% 81.6%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 48.0 3.83e-01 100.0% 78.2%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 40.0 3.85e-01 78.8% 77.2%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 39.0 4.16e-01 75.4% 92.1%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.53 37.0 4.15e-01 83.9% 96.6%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 48.0 4.10e-01 100.0% 91.6%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 42.0 4.39e-01 96.6% 90.2%
4c3eM00 1.20.120.1350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain 0.52 46.0 4.19e-01 95.8% 79.4%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.52 35.0 4.09e-01 79.7% 98.8%
7xk2R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 44.0 3.53e-01 96.6% 55.1%
8sbeA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 46.0 3.95e-01 100.0% 62.2%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 37.0 3.99e-01 89.0% 87.1%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.50 35.0 3.79e-01 78.8% 87.6%
ECOD (76)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4465966 632.11.1.10 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › EzrA 0.79 59.0 5.67e-01 76.3% 81.5%
3763162 601.16.1.0 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.78 72.0 6.59e-01 100.0% 85.3%
3692941 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.77 70.0 5.92e-01 97.5% 64.9%
3884035 611.2.1.0 alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) 0.77 55.0 5.38e-01 72.9% 74.4%
4994051 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.76 67.0 6.87e-01 99.2% 99.1%
4983097 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.76 55.0 5.71e-01 74.6% 80.0%
4987618 632.18.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.76 52.0 5.34e-01 72.9% 73.0%
4388995 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.75 69.0 5.18e-01 100.0% 44.4%
4940100 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.75 40.0 3.62e-01 100.0% 40.0%
3968650 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.75 54.0 5.68e-01 74.6% 89.5%
5076088 5039.1.1.0 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like 0.75 65.0 6.25e-01 94.9% 98.5%
4567743 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.74 68.0 5.86e-01 100.0% 71.1%
3619004 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.73 67.0 6.68e-01 99.2% 100.0%
4028444 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.73 65.0 6.50e-01 99.2% 95.0%
3463158 601.18.1.1 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PsbQ 0.73 65.0 6.51e-01 99.2% 96.6%
4981575 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.73 65.0 6.22e-01 98.3% 87.4%
3396797 601.1.1.43 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Serendipity_A 0.73 62.0 6.45e-01 95.8% 100.0%
5014075 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.72 53.0 5.93e-01 88.1% 98.9%
3272925 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.72 65.0 6.42e-01 100.0% 100.0%
3838201 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.71 63.0 5.51e-01 100.0% 64.6%
3473135 601.16.1.2 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › Focal_AT 0.71 65.0 6.49e-01 100.0% 100.0%
3995987 192.29.1.31 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CRIC_ras_sig 0.71 65.0 6.06e-01 100.0% 84.8%
3241030 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.71 57.0 4.13e-01 85.6% 70.8%
3918141 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.70 49.0 4.80e-01 72.0% 69.2%
3221738 192.29.1.172 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 0.70 60.0 5.73e-01 94.1% 89.3%
3680262 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.70 50.0 4.97e-01 74.6% 77.6%
3734736 3684.1.1.22 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › Opi1 0.70 65.0 5.89e-01 100.0% 83.2%
3711619 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.69 62.0 5.76e-01 99.2% 80.7%
3171827 192.29.1.4 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Opi1 0.69 62.0 6.00e-01 100.0% 92.6%
4966267 632.18.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.69 50.0 4.99e-01 74.6% 73.3%
3973161 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.69 60.0 4.86e-01 92.4% 54.3%
4945588 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.69 62.0 5.50e-01 100.0% 95.3%
3913373 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 61.0 6.14e-01 98.3% 100.0%
3466653 192.29.1.101 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Rx_N 0.68 59.0 5.98e-01 97.5% 97.4%
4377277 601.25.1.1 alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.67 60.0 5.47e-01 100.0% 80.6%
4133341 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.67 60.0 6.03e-01 100.0% 100.0%
5005799 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.66 59.0 4.92e-01 99.2% 69.0%
3220791 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.66 59.0 5.07e-01 99.2% 98.9%
3800481 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.66 50.0 4.61e-01 78.8% 65.3%
4137366 109.3.1.181 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Serinc 0.66 48.0 4.30e-01 74.6% 55.0%
5004597 5069.1.1.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF27518 0.66 59.0 4.79e-01 100.0% 58.5%
3638493 601.16.1.0 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.66 59.0 5.36e-01 100.0% 78.1%
3975942 601.4.1.6 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain 0.65 59.0 5.75e-01 100.0% 96.9%
5039837 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.65 58.0 4.91e-01 100.0% 67.5%
3629032 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.65 58.0 5.20e-01 100.0% 80.6%
4992935 5069.1.1.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF27518 0.65 58.0 4.95e-01 100.0% 69.6%
5069603 601.18.1.30 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Cytochrom_C_asm 0.63 57.0 5.65e-01 100.0% 96.0%
4001372 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.63 55.0 4.06e-01 96.6% 37.5%
4008078 601.4.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH 0.63 56.0 4.95e-01 100.0% 76.0%
4125854 601.25.1.1 alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.63 57.0 5.13e-01 100.0% 86.3%
4879693 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.62 56.0 5.33e-01 100.0% 89.8%
4097522 601.25.1.1 alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.62 56.0 5.15e-01 100.0% 78.1%
3308733 5069.1.1.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF27518 0.62 54.0 4.47e-01 100.0% 56.1%
3614951 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 54.0 4.96e-01 98.3% 75.5%
3499026 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.61 54.0 4.97e-01 100.0% 90.3%
3688401 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.61 44.0 3.32e-01 75.4% 81.4%
3885645 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.60 54.0 4.67e-01 100.0% 64.9%
3899959 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 44.0 4.65e-01 74.6% 98.1%
3465926 109.4.1.359 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.60 42.0 3.27e-01 72.0% 50.2%
4952530 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.59 52.0 5.06e-01 98.3% 100.0%
4952520 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.59 52.0 4.35e-01 100.0% 64.2%
5037184 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.58 53.0 4.44e-01 100.0% 59.5%
4045999 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.58 53.0 4.43e-01 100.0% 59.5%
3323416 3831.1.1.7 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › DUF842 0.57 41.0 4.30e-01 73.7% 95.2%
3453619 601.4.1.12 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B 0.57 50.0 4.63e-01 100.0% 85.8%
5055257 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.56 46.0 3.91e-01 89.0% 80.0%
5013911 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.56 50.0 4.07e-01 100.0% 64.8%
3391705 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.56 41.0 3.00e-01 75.4% 82.8%
3631038 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.56 51.0 4.20e-01 100.0% 58.1%
3641813 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.55 40.0 4.46e-01 76.3% 93.7%
5032080 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 47.0 4.82e-01 100.0% 97.4%
4051999 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.55 48.0 3.96e-01 100.0% 60.4%
3263613 601.1.1.97 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DNA_repr_REX1B 0.53 48.0 4.39e-01 100.0% 79.4%
4474640 604.1.1.150 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF28954 0.53 39.0 3.91e-01 78.8% 96.0%
3567414 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 38.0 3.69e-01 79.7% 85.2%
5044815 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.50 40.0 4.13e-01 85.6% 97.4%