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MW452941.1__QRV71454.1__MEP301_gp26__00026
Bact-VirMW452941.1__QRV71454.1__MEP301_gp26__00026
Identity
- Accession:
- MW452941 ↗
- Kingdom:
- phage
Quality
84.7
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 44-179
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7e5aB02 | 1.20.1000.10 | Mainly Alpha › Up-down Bundle › Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 › Guanylate-binding protein, C-terminal domain | 0.74 | 50.0 | 4.72e-01 | 100.0% | 57.3% |
| 2wzkA02 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.71 | 58.0 | 5.96e-01 | 86.0% | 98.4% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 39.0 | 3.83e-01 | 81.6% | 49.7% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.70 | 53.0 | 5.82e-01 | 85.3% | 100.0% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.69 | 36.0 | 3.51e-01 | 76.5% | 44.5% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.66 | 38.0 | 4.54e-01 | 83.8% | 81.9% |
| 2bvlA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 38.0 | 4.54e-01 | 86.8% | 88.4% |
| 6tqpA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.65 | 39.0 | 3.96e-01 | 80.9% | 58.8% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.64 | 48.0 | 4.55e-01 | 77.9% | 95.1% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 37.0 | 4.47e-01 | 86.8% | 88.2% |
| 2fcwA00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.64 | 38.0 | 4.29e-01 | 82.4% | 75.5% |
| 5d91A02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.64 | 42.0 | 3.74e-01 | 77.2% | 46.0% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.63 | 40.0 | 4.78e-01 | 83.8% | 97.7% |
| 3snhA02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.63 | 37.0 | 3.20e-01 | 79.4% | 37.0% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.62 | 49.0 | 4.27e-01 | 82.4% | 61.6% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.62 | 47.0 | 5.03e-01 | 95.6% | 91.5% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.61 | 37.0 | 4.11e-01 | 80.1% | 77.7% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 48.0 | 4.33e-01 | 89.0% | 61.3% |
| 2w31A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 43.0 | 4.18e-01 | 73.5% | 67.1% |
| 2dw4A03 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.60 | 37.0 | 4.23e-01 | 85.3% | 82.2% |
| 5cqgA05 | 1.10.357.90 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Telomerase reverse transcriptase (TERT), thumb domain | 0.60 | 46.0 | 4.12e-01 | 80.1% | 59.3% |
| 2ibdA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 39.0 | 3.86e-01 | 89.0% | 61.2% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 36.0 | 2.98e-01 | 83.8% | 32.7% |
| 1v9dB00 | 1.20.58.2220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain | 0.60 | 50.0 | 3.79e-01 | 89.7% | 73.5% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.59 | 40.0 | 3.83e-01 | 83.8% | 59.9% |
| 1urvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.58 | 40.0 | 3.89e-01 | 70.6% | 70.8% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 38.0 | 3.94e-01 | 80.9% | 69.2% |
| 3b81A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 46.0 | 4.13e-01 | 84.6% | 61.7% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.56 | 38.0 | 4.26e-01 | 84.6% | 86.9% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.56 | 44.0 | 3.86e-01 | 81.6% | 58.9% |
| 3hyuA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 38.0 | 3.85e-01 | 71.3% | 69.5% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 36.0 | 3.00e-01 | 77.2% | 38.4% |
| 3fhnA01 | 6.10.280.210 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A | 0.55 | 49.0 | 4.41e-01 | 97.1% | 70.7% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.55 | 42.0 | 4.27e-01 | 100.0% | 80.3% |
| 3tejA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.55 | 46.0 | 3.59e-01 | 93.4% | 77.5% |
| 2icwG01 | 1.20.120.390 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hla class ii histocompatibility antigen, dr alpha chain. Chain D, domain 1 | 0.53 | 36.0 | 3.75e-01 | 90.4% | 74.2% |
| 1foeA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.53 | 41.0 | 3.61e-01 | 81.6% | 65.0% |
| 1a00B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 38.0 | 3.71e-01 | 73.5% | 72.6% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 37.0 | 3.67e-01 | 73.5% | 100.0% |
| 1x9fC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 37.0 | 3.59e-01 | 74.3% | 66.4% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.52 | 44.0 | 3.39e-01 | 91.9% | 93.6% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 41.0 | 4.26e-01 | 98.5% | 92.1% |
| 8ipqB01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.51 | 39.0 | 3.08e-01 | 80.9% | 99.3% |
| 4xvxA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 35.0 | 3.40e-01 | 82.4% | 64.6% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.50 | 38.0 | 3.43e-01 | 77.9% | 71.3% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4182059 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.71 | 51.0 | 5.65e-01 | 94.1% | 91.8% |
| 3333216 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.69 | 47.0 | 5.48e-01 | 94.9% | 100.0% |
| 3947741 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.67 | 37.0 | 3.95e-01 | 86.0% | 60.8% |
| 3246540 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.65 | 49.0 | 4.35e-01 | 78.7% | 61.1% |
| 3678146 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.62 | 46.0 | 4.62e-01 | 100.0% | 75.0% |
| 4974185 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.62 | 48.0 | 3.96e-01 | 82.4% | 91.2% |
| 4975177 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.61 | 47.0 | 3.72e-01 | 82.4% | 89.8% |
| 3682340 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.60 | 40.0 | 3.91e-01 | 88.2% | 60.7% |
| 3806463 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.60 | 40.0 | 3.90e-01 | 86.8% | 59.4% |
| 4263879 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.59 | 36.0 | 3.94e-01 | 86.8% | 71.3% |
| 4322534 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.59 | 34.0 | 3.86e-01 | 83.8% | 72.4% |
| 3741889 | 109.4.1.103 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GLE1 | 0.59 | 51.0 | 4.02e-01 | 94.1% | 85.3% |
| 3785556 | 5051.1.1.9 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Transp_cyt_pur | 0.59 | 46.0 | 3.15e-01 | 82.4% | 54.9% |
| 3742628 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 54.0 | 5.22e-01 | 100.0% | 91.6% |
| 3838243 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.56 | 38.0 | 3.89e-01 | 89.7% | 69.6% |
| 3600943 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 42.0 | 3.64e-01 | 80.1% | 52.0% |
| 3767783 | 192.2.1.19 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › FAM186A-B_C | 0.56 | 42.0 | 4.05e-01 | 80.1% | 69.3% |
| 3795653 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.56 | 40.0 | 3.97e-01 | 72.8% | 92.9% |
| 3470751 | 3755.3.1.297 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 | 0.56 | 39.0 | 3.69e-01 | 83.8% | 60.6% |
| 4115372 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.55 | 35.0 | 3.85e-01 | 77.2% | 78.2% |
| 3462375 | 3755.4.1.46 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › NET2A | 0.54 | 43.0 | 3.72e-01 | 83.8% | 81.4% |
| 3827397 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.54 | 33.0 | 3.49e-01 | 75.0% | 68.7% |
| 4989670 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.54 | 42.0 | 3.66e-01 | 82.4% | 56.7% |
| 4469387 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.54 | 34.0 | 3.61e-01 | 88.2% | 70.8% |
| 3778624 | 627.1.1.0 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain | 0.54 | 38.0 | 4.38e-01 | 93.4% | 100.0% |
| 3428852 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.54 | 41.0 | 4.19e-01 | 83.8% | 82.2% |
| 4175809 | 5086.1.1.88 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CyaD | 0.54 | 39.0 | 3.72e-01 | 86.0% | 63.0% |
| 3398185 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.53 | 37.0 | 3.53e-01 | 86.0% | 61.3% |
| 3288790 | 1075.1.1.28 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › PF30402 | 0.52 | 46.0 | 3.74e-01 | 96.3% | 58.0% |
| 3923874 | 109.4.1.37 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 | 0.51 | 45.0 | 3.39e-01 | 99.3% | 61.9% |
| 4143464 | 4177.1.1.102 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Med29 | 0.51 | 37.0 | 3.58e-01 | 82.4% | 65.2% |
| 3591530 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.51 | 32.0 | 3.36e-01 | 74.3% | 66.9% |
D2
high
residues 193-301
Domain cluster:
representative
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3fhnA03 | 1.10.357.100 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Dsl1p vesicle tethering complex, Tip20p subunit, domain C | 0.71 | 58.0 | 4.94e-01 | 87.2% | 64.9% |
| 2jbyA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.67 | 42.0 | 4.01e-01 | 83.5% | 52.8% |
| 2a2fX02 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.66 | 60.0 | 5.69e-01 | 99.1% | 94.6% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.64 | 46.0 | 4.73e-01 | 73.4% | 82.4% |
| 3tdoA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.60 | 52.0 | 4.03e-01 | 97.2% | 77.8% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 42.0 | 4.32e-01 | 73.4% | 91.6% |
| 6nsjA00 | 1.25.40.600 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter | 0.59 | 39.0 | 3.36e-01 | 71.6% | 40.7% |
| 1qqtA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.58 | 50.0 | 4.59e-01 | 98.2% | 72.5% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.58 | 47.0 | 3.86e-01 | 87.2% | 79.8% |
| 1ya0A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 49.0 | 4.06e-01 | 94.5% | 75.2% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.58 | 51.0 | 5.11e-01 | 100.0% | 96.4% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 47.0 | 3.80e-01 | 90.8% | 89.6% |
| 2iakA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 41.0 | 3.40e-01 | 74.3% | 44.3% |
| 3f1xA01 | 1.10.3130.10 | Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 | 0.57 | 39.0 | 3.51e-01 | 78.9% | 50.3% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.57 | 44.0 | 4.42e-01 | 82.6% | 84.4% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 45.0 | 4.11e-01 | 86.2% | 73.1% |
| 3zheC01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 47.0 | 4.00e-01 | 92.7% | 58.2% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 40.0 | 4.08e-01 | 74.3% | 81.0% |
| 2x64A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 43.0 | 4.27e-01 | 82.6% | 80.5% |
| 2epkX03 | 1.20.120.670 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › N-acetyl-b-d-glucoasminidase | 0.55 | 48.0 | 3.89e-01 | 100.0% | 75.9% |
| 1vdyA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 43.0 | 4.01e-01 | 86.2% | 85.0% |
| 1a00B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 41.0 | 3.80e-01 | 83.5% | 67.8% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.53 | 38.0 | 3.84e-01 | 95.4% | 72.6% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 44.0 | 4.03e-01 | 92.7% | 92.6% |
| 3gs3A00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.53 | 45.0 | 3.53e-01 | 96.3% | 48.6% |
| 5mi7A03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.52 | 43.0 | 3.25e-01 | 88.1% | 48.1% |
| 2xpzA04 | 1.25.40.320 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain | 0.52 | 45.0 | 3.93e-01 | 94.5% | 80.6% |
| 1ywfA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.52 | 41.0 | 3.25e-01 | 87.2% | 78.4% |
| 2ctqA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.51 | 37.0 | 3.97e-01 | 93.6% | 89.4% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3934625 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.77 | 54.0 | 5.11e-01 | 71.6% | 64.0% |
| 4943661 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.71 | 58.0 | 4.63e-01 | 86.2% | 81.0% |
| 3929364 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.71 | 50.0 | 4.83e-01 | 73.4% | 64.8% |
| 3378189 | 5076.2.1.9 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › Choline_transpo | 0.69 | 47.0 | 3.51e-01 | 70.6% | 96.7% |
| 3713657 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.67 | 47.0 | 4.08e-01 | 73.4% | 80.6% |
| 3500715 | 633.24.1.2 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › DUF5601 | 0.66 | 46.0 | 5.22e-01 | 78.9% | 96.2% |
| 4941712 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.65 | 46.0 | 4.01e-01 | 85.3% | 47.6% |
| 3644241 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.64 | 45.0 | 4.35e-01 | 72.5% | 81.6% |
| 3582053 | 601.1.2.64 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_VBS2 | 0.62 | 40.0 | 4.14e-01 | 80.7% | 67.6% |
| 3642682 | 603.1.1.5 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N | 0.62 | 43.0 | 4.23e-01 | 70.6% | 96.5% |
| 3267624 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.61 | 44.0 | 4.12e-01 | 82.6% | 60.7% |
| 3615242 | 109.4.1.85 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nop52 | 0.60 | 54.0 | 3.72e-01 | 100.0% | 47.9% |
| 3709727 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 51.0 | 3.72e-01 | 92.7% | 60.0% |
| 3708240 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.60 | 53.0 | 4.19e-01 | 100.0% | 83.0% |
| 5020664 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.60 | 50.0 | 3.94e-01 | 88.1% | 69.5% |
| 2492086 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.59 | 44.0 | 3.96e-01 | 77.1% | 58.5% |
| 3937968 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.59 | 41.0 | 3.57e-01 | 70.6% | 71.5% |
| 3940375 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.58 | 43.0 | 3.65e-01 | 78.9% | 54.4% |
| 3926326 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.57 | 44.0 | 4.12e-01 | 82.6% | 89.6% |
| 3496802 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 50.0 | 3.64e-01 | 97.2% | 47.3% |
| 3194704 | 109.6.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF_N | 0.55 | 46.0 | 4.19e-01 | 95.4% | 71.0% |
| 4025667 | 109.4.1.70 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID | 0.55 | 45.0 | 4.24e-01 | 99.1% | 74.1% |
| 4020813 | 109.6.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF | 0.54 | 48.0 | 3.26e-01 | 100.0% | 36.7% |
| 5000552 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.53 | 43.0 | 4.45e-01 | 88.1% | 95.0% |
D3
medium
residues 315-422
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3t69A02 | 3.30.420.310 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 2-keto-3-deoxy-galactonokinase, C-terminal domain | 0.57 | 42.0 | 3.33e-01 | 91.7% | 37.2% |
| 4mk3A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 31.0 | 3.04e-01 | 88.0% | 50.4% |
| 1w36C06 | 1.10.10.990 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.54 | 31.0 | 3.73e-01 | 88.9% | 86.1% |
| 1v9dA01 | 1.20.58.630 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 32.0 | 3.50e-01 | 88.0% | 74.4% |
| 3vsjD00 | 3.40.830.10 | Alpha Beta › 3-Layer(aba) Sandwich › Protocatechuate 4,5-dioxygenase; Chain B › LigB-like | 0.52 | 45.0 | 3.38e-01 | 99.1% | 98.3% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4132373 | 3860.1.1.0 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm | 0.52 | 31.0 | 3.37e-01 | 84.3% | 71.1% |
| 3957626 | 2004.1.3.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR | 0.51 | 32.0 | 2.94e-01 | 83.3% | 45.3% |
| 2642997 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 43.0 | 3.63e-01 | 95.4% | 94.8% |
D4
medium
residues 423-567
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2w43A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.68 | 27.0 | 4.16e-01 | 86.2% | 91.2% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 26.0 | 3.57e-01 | 78.6% | 73.0% |
| 2no4A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.63 | 31.0 | 4.14e-01 | 93.8% | 89.3% |
| 2gsqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 29.0 | 3.34e-01 | 89.0% | 62.0% |
| 2pvqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 28.0 | 3.18e-01 | 77.2% | 57.5% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 44.0 | 3.89e-01 | 94.5% | 75.2% |
| 1knvB00 | 3.40.91.10 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › | 0.51 | 40.0 | 3.20e-01 | 82.8% | 86.3% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.50 | 37.0 | 4.13e-01 | 87.6% | 98.2% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3206225 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.62 | 56.0 | 4.51e-01 | 100.0% | 83.2% |
| 3962191 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.62 | 31.0 | 3.82e-01 | 93.8% | 76.7% |
| 4011849 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.61 | 55.0 | 4.46e-01 | 100.0% | 89.5% |
| 3388938 | 632.22.1.7 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › Membralin | 0.61 | 40.0 | 3.46e-01 | 78.6% | 42.7% |
| 3992989 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.56 | 45.0 | 4.46e-01 | 84.1% | 93.3% |
| 4530958 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.55 | 43.0 | 3.16e-01 | 80.7% | 33.9% |
| 3507479 | 148.1.3.264 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PHO4 | 0.55 | 29.0 | 3.40e-01 | 93.8% | 72.0% |
| 3879373 | 621.1.1.1 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › GBP_C | 0.55 | 43.0 | 3.18e-01 | 81.4% | 44.0% |
| 4091932 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 39.0 | 4.05e-01 | 90.3% | 77.8% |
| 2075033 | 3787.1.1.0 ↗ | alpha bundles › HAD superfamily helical bundle insertion domain | 0.53 | 27.0 | 3.55e-01 | 92.4% | 88.6% |
| 3233240 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.53 | 47.0 | 3.88e-01 | 99.3% | 92.0% |
| 3941867 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.53 | 47.0 | 4.10e-01 | 94.5% | 89.0% |
| 3929364 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.53 | 39.0 | 4.20e-01 | 95.2% | 90.4% |
| 3870376 | 194.1.1.3 ↗ | alpha complex topology › Serum albumin-like › Serum albumin-like › Serum albumin-like › ECM1 | 0.52 | 37.0 | 3.90e-01 | 93.1% | 79.3% |
| 3596865 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 37.0 | 3.44e-01 | 94.5% | 58.9% |
| 3565626 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.52 | 38.0 | 3.80e-01 | 94.5% | 72.3% |
| 3820263 | 7016.1.1.0 ↗ | extended segments › Palmitoyltransferase DHHC C-terminal domain › Palmitoyltransferase DHHC C-terminal domain › Palmitoyltransferase DHHC C-terminal domain | 0.51 | 40.0 | 4.01e-01 | 89.0% | 80.7% |