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MW584212.1__QST90789.1__PROPHIGD13-2_27__00026
Bact-VirMW584212.1__QST90789.1__PROPHIGD13-2_27__00026
Identity
- Accession:
- MW584212 ↗
- Kingdom:
- phage
Quality
65.7
mean pLDDT
Taxonomy
TaxID: 2813241
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 79-165
Domain cluster:
representative
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.74 | 51.0 | 4.56e-01 | 72.4% | 90.3% |
| 1m6nA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.71 | 61.0 | 5.27e-01 | 100.0% | 60.7% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.71 | 58.0 | 5.27e-01 | 100.0% | 65.8% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.69 | 45.0 | 4.03e-01 | 98.9% | 46.8% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.67 | 61.0 | 4.63e-01 | 100.0% | 46.5% |
| 2o36A01 | 1.20.1050.40 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 | 0.67 | 45.0 | 3.99e-01 | 81.6% | 47.7% |
| 5d1rB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.67 | 44.0 | 3.23e-01 | 80.5% | 25.7% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.67 | 45.0 | 4.41e-01 | 77.0% | 62.9% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.67 | 50.0 | 4.36e-01 | 100.0% | 52.7% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 59.0 | 4.19e-01 | 100.0% | 77.9% |
| 2e9xB02 | 1.20.58.1020 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 43.0 | 4.03e-01 | 83.9% | 54.1% |
| 3fcnA00 | 1.20.1220.20 | Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Uncharcterised protein PF01724 | 0.64 | 52.0 | 4.29e-01 | 88.5% | 56.3% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 57.0 | 4.06e-01 | 100.0% | 75.6% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 56.0 | 3.97e-01 | 98.9% | 73.5% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 49.0 | 4.67e-01 | 81.6% | 70.7% |
| 1s7bA00 | 1.10.3730.20 | Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › | 0.64 | 45.0 | 4.22e-01 | 100.0% | 60.4% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.63 | 44.0 | 4.65e-01 | 72.4% | 80.8% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 56.0 | 4.06e-01 | 100.0% | 75.1% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 56.0 | 4.28e-01 | 100.0% | 76.0% |
| 3ripA02 | 1.20.120.1900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain | 0.62 | 55.0 | 3.86e-01 | 100.0% | 51.3% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 53.0 | 4.45e-01 | 100.0% | 56.7% |
| 3ddeB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.60 | 47.0 | 3.45e-01 | 82.8% | 83.1% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.60 | 52.0 | 3.93e-01 | 100.0% | 39.2% |
| 3rm5B02 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.60 | 49.0 | 3.59e-01 | 87.4% | 80.4% |
| 3i2wA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 54.0 | 3.84e-01 | 100.0% | 74.8% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 48.0 | 4.32e-01 | 100.0% | 63.6% |
| 7cfmR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 52.0 | 3.74e-01 | 100.0% | 39.9% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.59 | 52.0 | 3.96e-01 | 100.0% | 78.1% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 47.0 | 4.47e-01 | 89.7% | 81.3% |
| 3anwA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 44.0 | 4.11e-01 | 90.8% | 64.6% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 47.0 | 4.13e-01 | 90.8% | 63.1% |
| 1hqoA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 43.0 | 3.83e-01 | 87.4% | 55.7% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 44.0 | 3.92e-01 | 89.7% | 59.3% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.55 | 49.0 | 3.16e-01 | 98.9% | 71.3% |
| 4hfkB00 | 1.20.120.1620 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 41.0 | 3.99e-01 | 100.0% | 71.4% |
| 1rq0A01 | 6.10.140.160 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 45.0 | 4.64e-01 | 90.8% | 97.6% |
| 2yjkC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 48.0 | 3.94e-01 | 97.7% | 76.4% |
| 6pnjL00 | 1.20.1240.10 | Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI | 0.53 | 45.0 | 3.80e-01 | 96.6% | 57.1% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.53 | 47.0 | 3.85e-01 | 100.0% | 75.8% |
| 3bt5A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 47.0 | 3.93e-01 | 100.0% | 85.4% |
| 4mncA00 | 3.40.190.170 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7 | 0.52 | 41.0 | 2.82e-01 | 85.1% | 62.6% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 46.0 | 3.36e-01 | 100.0% | 66.9% |
| 2ihr101 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.50 | 43.0 | 4.09e-01 | 97.7% | 93.4% |
ECOD (48)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4884522 | 304.28.1.17 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sterol-sensing | 0.81 | 58.0 | 4.66e-01 | 73.6% | 42.0% |
| 4826095 | 5067.1.1.5 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Sterol-sensing | 0.81 | 58.0 | 5.65e-01 | 73.6% | 73.1% |
| 3838383 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.78 | 53.0 | 3.82e-01 | 70.1% | 50.4% |
| 3470992 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.75 | 56.0 | 5.34e-01 | 100.0% | 68.0% |
| 5031101 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.69 | 52.0 | 4.09e-01 | 79.3% | 59.4% |
| 3304304 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.68 | 47.0 | 4.48e-01 | 82.8% | 60.0% |
| 4886424 | 304.116.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in release factor › Ferredoxin-like domain in release factor › PCRF | 0.68 | 47.0 | 4.48e-01 | 71.3% | 99.0% |
| 3808 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.67 | 46.0 | 4.31e-01 | 71.3% | 58.5% |
| 3409452 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.66 | 52.0 | 5.30e-01 | 98.9% | 85.9% |
| 4948369 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.65 | 55.0 | 4.70e-01 | 92.0% | 71.0% |
| 4530342 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.65 | 45.0 | 4.25e-01 | 71.3% | 92.4% |
| 3615064 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.64 | 56.0 | 5.14e-01 | 97.7% | 78.3% |
| 3594378 | 109.5.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › adenylylcyclase associated protein, CAP-N › adenylylcyclase associated protein, CAP-N | 0.64 | 54.0 | 3.92e-01 | 90.8% | 97.8% |
| 3628561 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.64 | 56.0 | 4.97e-01 | 100.0% | 70.8% |
| 3633924 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.63 | 47.0 | 3.54e-01 | 81.6% | 32.1% |
| 3738219 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.63 | 51.0 | 3.81e-01 | 87.4% | 35.3% |
| 4025757 | 603.1.1.6 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 | 0.63 | 48.0 | 3.56e-01 | 81.6% | 35.0% |
| 3298709 | 605.1.1.141 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Rx_N | 0.61 | 54.0 | 4.79e-01 | 98.9% | 77.6% |
| 3712635 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.61 | 54.0 | 5.24e-01 | 100.0% | 90.5% |
| 3367913 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.61 | 46.0 | 3.95e-01 | 81.6% | 57.9% |
| 4274516 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.60 | 44.0 | 4.20e-01 | 78.2% | 90.5% |
| 3797833 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.60 | 54.0 | 4.20e-01 | 100.0% | 53.5% |
| 5059077 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.60 | 53.0 | 4.37e-01 | 100.0% | 83.1% |
| 3260603 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.59 | 52.0 | 4.23e-01 | 98.9% | 68.2% |
| 3606235 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.59 | 48.0 | 3.91e-01 | 89.7% | 85.9% |
| 3830860 | 109.46.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) | 0.59 | 34.0 | 2.93e-01 | 94.3% | 34.8% |
| 3770021 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.58 | 44.0 | 3.38e-01 | 81.6% | 39.0% |
| 3406218 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.58 | 48.0 | 4.49e-01 | 90.8% | 83.6% |
| 5055566 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.57 | 48.0 | 4.42e-01 | 92.0% | 72.2% |
| 3569629 | 109.4.1.33 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT | 0.57 | 44.0 | 2.88e-01 | 94.3% | 19.7% |
| 3807101 | 3684.1.1.20 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF4079 | 0.57 | 47.0 | 4.04e-01 | 100.0% | 54.5% |
| 4013947 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.57 | 47.0 | 3.44e-01 | 90.8% | 60.4% |
| 5062170 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 39.0 | 3.56e-01 | 72.4% | 79.2% |
| 3935107 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.57 | 47.0 | 4.35e-01 | 92.0% | 71.8% |
| 3317090 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.56 | 48.0 | 3.49e-01 | 95.4% | 85.0% |
| 3774553 | 223.2.1.22 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Folliculin | 0.56 | 43.0 | 3.09e-01 | 82.8% | 29.6% |
| 3316949 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.56 | 47.0 | 4.14e-01 | 97.7% | 85.2% |
| 4094257 | 150.3.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 | 0.55 | 49.0 | 4.28e-01 | 97.7% | 76.2% |
| 3863657 | 192.29.1.26 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › BAG6 | 0.55 | 42.0 | 3.83e-01 | 81.6% | 69.6% |
| 3192708 | 109.42.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › E3 ubiquitin-protein ligase SHPRH first helical domain › E3 ubiquitin-protein ligase SHPRH first helical domain | 0.55 | 45.0 | 3.56e-01 | 92.0% | 95.3% |
| 4156596 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.54 | 46.0 | 3.50e-01 | 97.7% | 81.8% |
| 4017831 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.53 | 38.0 | 3.14e-01 | 73.6% | 56.8% |
| 3464245 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.53 | 43.0 | 3.98e-01 | 90.8% | 80.0% |
| 3617771 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.53 | 47.0 | 4.34e-01 | 98.9% | 90.0% |
| 4235156 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.53 | 44.0 | 4.08e-01 | 98.9% | 85.8% |
| 3200543 | 109.4.1.368 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SHNi-TPR | 0.52 | 40.0 | 2.63e-01 | 83.9% | 21.0% |
| 4012748 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.51 | 44.0 | 3.02e-01 | 94.3% | 32.9% |
| 3391536 | 109.4.1.1393 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26715 | 0.50 | 34.0 | 2.23e-01 | 85.1% | 14.1% |
D2
medium
residues 166-261
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.68 | 38.0 | 3.05e-01 | 97.9% | 30.3% |
| 2iw3A02 | 1.20.1390.20 | Mainly Alpha › Up-down Bundle › PWI domain › | 0.67 | 43.0 | 4.49e-01 | 95.8% | 70.0% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.65 | 39.0 | 4.37e-01 | 82.3% | 77.0% |
| 1e3pA02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.65 | 44.0 | 4.65e-01 | 86.5% | 80.7% |
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.64 | 51.0 | 4.23e-01 | 87.5% | 51.7% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.63 | 42.0 | 3.60e-01 | 90.6% | 40.2% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.62 | 37.0 | 3.98e-01 | 82.3% | 69.5% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.62 | 33.0 | 3.56e-01 | 88.5% | 61.7% |
| 1jfaB00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.61 | 51.0 | 3.49e-01 | 91.7% | 31.7% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.60 | 37.0 | 3.84e-01 | 80.2% | 65.2% |
| 2f07B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 42.0 | 3.36e-01 | 81.2% | 36.2% |
| 5kbwB00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.59 | 48.0 | 4.05e-01 | 91.7% | 53.2% |
| 1ivhA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 42.0 | 3.75e-01 | 77.1% | 54.6% |
| 8b9zK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 42.0 | 4.29e-01 | 91.7% | 79.1% |
| 3rlbA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.58 | 47.0 | 3.97e-01 | 91.7% | 64.8% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.57 | 48.0 | 3.50e-01 | 88.5% | 57.0% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 44.0 | 3.66e-01 | 89.6% | 48.4% |
| 3ug9A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 50.0 | 3.74e-01 | 93.8% | 94.2% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 46.0 | 4.26e-01 | 85.4% | 85.8% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.57 | 45.0 | 4.01e-01 | 83.3% | 61.7% |
| 7y3eA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.57 | 47.0 | 3.12e-01 | 91.7% | 65.1% |
| 7w9wA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 44.0 | 3.19e-01 | 82.3% | 79.0% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 42.0 | 4.14e-01 | 78.1% | 77.7% |
| 7eu3E01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 44.0 | 4.61e-01 | 97.9% | 92.0% |
| 6k41R00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 44.0 | 3.29e-01 | 84.4% | 38.7% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 40.0 | 3.59e-01 | 76.0% | 58.0% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 47.0 | 3.87e-01 | 91.7% | 88.1% |
| 3behB01 | 1.20.120.540 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels | 0.55 | 43.0 | 4.02e-01 | 83.3% | 77.8% |
| 1fouA01 | 1.10.246.30 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.55 | 39.0 | 4.33e-01 | 88.5% | 95.9% |
| 3euaA02 | 1.10.10.2240 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.55 | 33.0 | 3.91e-01 | 93.8% | 90.6% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.55 | 41.0 | 3.83e-01 | 79.2% | 92.4% |
| 2yx8A00 | 1.10.150.510 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family | 0.55 | 36.0 | 3.83e-01 | 82.3% | 79.0% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.54 | 46.0 | 3.65e-01 | 94.8% | 91.1% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 46.0 | 3.44e-01 | 90.6% | 47.3% |
| 3g67A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.54 | 45.0 | 3.41e-01 | 88.5% | 70.4% |
| 4bemJ00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.53 | 44.0 | 3.59e-01 | 90.6% | 59.1% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.53 | 40.0 | 4.02e-01 | 87.5% | 77.0% |
| 3ripA02 | 1.20.120.1900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain | 0.53 | 45.0 | 3.27e-01 | 94.8% | 38.7% |
| 2uxwA01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 37.0 | 2.95e-01 | 72.9% | 54.8% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.52 | 39.0 | 3.42e-01 | 87.5% | 52.8% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.51 | 42.0 | 3.62e-01 | 90.6% | 63.5% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.50 | 38.0 | 3.45e-01 | 80.2% | 71.0% |
| 6lumG01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.50 | 42.0 | 4.03e-01 | 94.8% | 89.3% |
| 4dvyP01 | 1.10.357.130 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.50 | 44.0 | 3.49e-01 | 96.9% | 78.2% |
| 1ldjA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.50 | 38.0 | 3.61e-01 | 81.2% | 71.3% |
ECOD (53)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1883344 | 604.39.1.4 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ABC_cobalt | 0.73 | 57.0 | 4.43e-01 | 92.7% | 40.1% |
| 4196356 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.68 | 45.0 | 4.21e-01 | 100.0% | 54.2% |
| 4029863 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.68 | 42.0 | 4.00e-01 | 90.6% | 52.7% |
| 3179413 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.67 | 50.0 | 3.44e-01 | 78.1% | 30.6% |
| 4632513 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.65 | 59.0 | 4.32e-01 | 99.0% | 85.3% |
| 3886622 | 192.29.1.57 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Ninjurin | 0.64 | 42.0 | 3.70e-01 | 92.7% | 47.4% |
| 3250022 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.63 | 58.0 | 4.26e-01 | 100.0% | 88.5% |
| 4659183 | 1079.1.1.13 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Mntp | 0.62 | 47.0 | 4.12e-01 | 81.2% | 72.0% |
| 3368923 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.62 | 50.0 | 4.12e-01 | 91.7% | 47.2% |
| 3623710 | 3277.2.1.1 ↗ | alpha arrays › Thymine dioxygenase JBP1 DNA-binding domain-like › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › CHD1-like_C | 0.61 | 40.0 | 3.95e-01 | 82.3% | 61.0% |
| 3960319 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.61 | 48.0 | 3.97e-01 | 84.4% | 48.2% |
| 3718013 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.61 | 45.0 | 4.52e-01 | 81.2% | 78.9% |
| 4929490 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.60 | 46.0 | 4.70e-01 | 88.5% | 83.2% |
| 4028110 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 55.0 | 4.32e-01 | 100.0% | 84.1% |
| 4264622 | 604.39.1.5 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ECF_trnsprt | 0.60 | 51.0 | 4.20e-01 | 96.9% | 52.5% |
| 3620725 | 5041.1.1.17 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › Periphilin_C | 0.60 | 48.0 | 4.70e-01 | 86.5% | 87.6% |
| 3936772 | 5050.1.1.11 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 | 0.59 | 54.0 | 4.16e-01 | 99.0% | 69.8% |
| 3191997 | 5041.1.1.15 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › Tmemb_170 | 0.58 | 41.0 | 3.92e-01 | 85.4% | 62.7% |
| 3731029 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.58 | 37.0 | 3.28e-01 | 90.6% | 45.9% |
| 4306685 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.58 | 52.0 | 3.97e-01 | 100.0% | 94.6% |
| 4011531 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 43.0 | 3.24e-01 | 79.2% | 93.6% |
| 4952080 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.57 | 49.0 | 3.85e-01 | 94.8% | 95.1% |
| 4443875 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 45.0 | 3.48e-01 | 86.5% | 45.7% |
| 3971686 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.57 | 49.0 | 4.35e-01 | 95.8% | 100.0% |
| 5019967 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.57 | 48.0 | 3.90e-01 | 93.8% | 100.0% |
| 5019542 | 622.4.1.67 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › DUF5518 | 0.57 | 45.0 | 4.48e-01 | 84.4% | 84.8% |
| 3945179 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 43.0 | 3.45e-01 | 83.3% | 54.5% |
| 3442159 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 43.0 | 4.36e-01 | 80.2% | 89.5% |
| 3695830 | 633.24.1.7 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › TMD_POM152 | 0.56 | 43.0 | 4.57e-01 | 90.6% | 94.1% |
| 4456090 | 5086.1.1.94 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HB_LcnD | 0.56 | 46.0 | 3.52e-01 | 89.6% | 40.0% |
| 5002083 | 1076.1.1.4 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › PrsW-protease | 0.56 | 46.0 | 3.99e-01 | 91.7% | 85.8% |
| 4081378 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.55 | 49.0 | 3.79e-01 | 99.0% | 96.8% |
| 4609538 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 42.0 | 3.98e-01 | 86.5% | 67.8% |
| 4946108 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 46.0 | 3.70e-01 | 92.7% | 73.1% |
| 3785416 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 48.0 | 3.85e-01 | 100.0% | 76.0% |
| 5038702 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 44.0 | 3.37e-01 | 85.4% | 67.8% |
| 4958350 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.54 | 45.0 | 3.58e-01 | 91.7% | 93.6% |
| 3961527 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.54 | 44.0 | 3.79e-01 | 86.5% | 74.5% |
| 4997390 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.54 | 44.0 | 4.40e-01 | 87.5% | 89.0% |
| 5046440 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 46.0 | 3.75e-01 | 100.0% | 74.0% |
| 4974383 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.53 | 44.0 | 3.46e-01 | 91.7% | 46.8% |
| 4449404 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 42.0 | 3.25e-01 | 88.5% | 43.8% |
| 5024781 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 42.0 | 3.47e-01 | 86.5% | 61.7% |
| 3407944 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 43.0 | 3.36e-01 | 90.6% | 86.0% |
| 3539318 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 44.0 | 3.55e-01 | 92.7% | 98.4% |
| 5026211 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 43.0 | 3.56e-01 | 90.6% | 58.3% |
| 4846601 | 603.5.1.1 ↗ | alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN | 0.51 | 41.0 | 3.83e-01 | 87.5% | 74.6% |
| 4106751 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 40.0 | 2.98e-01 | 86.5% | 36.3% |
| 3931480 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 40.0 | 4.13e-01 | 95.8% | 92.2% |
| 3910521 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.51 | 41.0 | 4.05e-01 | 88.5% | 81.0% |
| 4014071 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 41.0 | 3.14e-01 | 91.7% | 37.0% |
| 3999712 | 101.11.1.4 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › EMC6 | 0.50 | 43.0 | 4.50e-01 | 97.9% | 100.0% |
| 4324052 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 42.0 | 3.30e-01 | 92.7% | 47.1% |