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MW749006.1__QXN70599.1__AGENTSMITH_195__00193

Bact-Vir

MW749006.1__QXN70599.1__AGENTSMITH_195__00193

Identity

Accession:
MW749006 ↗
Kingdom:
phage

Quality

82.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 173-295
PDB
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 32.0 3.70e-01 94.3% 60.9%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.66 30.0 4.10e-01 91.1% 82.1%
4jioA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.63 33.0 2.98e-01 97.6% 37.9%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 31.0 3.38e-01 97.6% 56.0%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 33.0 4.28e-01 93.5% 90.1%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.61 34.0 3.22e-01 93.5% 46.6%
4ke2A00 6.10.140.1860 Special › Helix non-globular › Helix Hairpins › 0.59 32.0 2.74e-01 100.0% 33.2%
1mqsA04 1.25.40.60 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.58 42.0 4.53e-01 82.1% 89.3%
1vkeB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.58 41.0 4.43e-01 79.7% 89.1%
3p4tA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 31.0 2.97e-01 97.6% 45.3%
1yq3C02 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.55 32.0 3.41e-01 91.9% 64.8%
1kmiZ02 1.10.287.500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.54 32.0 3.16e-01 96.7% 54.5%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 32.0 3.08e-01 96.7% 51.8%
1hciA03 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 32.0 3.32e-01 94.3% 60.8%
1t33A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 38.0 3.57e-01 73.2% 82.3%
4jgwA02 1.10.840.10 Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain 0.54 39.0 3.23e-01 77.2% 99.6%
2lt3A01 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.53 37.0 4.05e-01 83.7% 89.0%
3njcA00 3.30.1380.20 Alpha Beta › 2-Layer Sandwich › Muramoyl-pentapeptide Carboxypeptidase; domain 2 › Trafficking protein particle complex subunit 3 0.53 42.0 3.93e-01 85.4% 80.4%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.52 31.0 3.59e-01 94.3% 79.6%
1x3kA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 37.0 3.56e-01 76.4% 89.1%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3945031 5086.1.1.86 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG 0.63 30.0 3.01e-01 95.9% 42.3%
3578718 101.1.6.0 alpha arrays › HTH › HTH › TrpR 0.61 42.0 4.62e-01 100.0% 89.5%
5028327 5060.2.1.1 alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF 0.58 34.0 2.98e-01 88.6% 35.4%
5078706 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.56 47.0 3.56e-01 89.4% 40.7%
3489232 109.4.1.543 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › efThoc1 0.56 41.0 3.68e-01 80.5% 54.3%
3245018 109.4.1.543 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › efThoc1 0.55 40.0 3.43e-01 79.7% 44.2%
3744152 551.1.1.1 alpha arrays › Hsp90 co-chaperone CDC37 middle domain › Hsp90 co-chaperone CDC37 middle domain › Hsp90 co-chaperone CDC37 middle domain › CDC37_M 0.53 41.0 4.09e-01 81.3% 100.0%
3499765 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 41.0 3.25e-01 87.0% 67.4%
3836575 601.1.1.40 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PGG 0.51 43.0 4.15e-01 92.7% 94.3%
3735816 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.50 43.0 3.01e-01 97.6% 70.1%
D2 medium residues 1-77
PDB
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2p7vA00 1.20.120.1370 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 0.70 52.0 4.21e-01 80.5% 61.6%
1z23A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.69 53.0 4.18e-01 83.1% 59.5%
1zylA03 1.20.1270.170 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.69 58.0 5.30e-01 94.8% 100.0%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.68 59.0 5.33e-01 98.7% 96.3%
1ad6A00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.68 60.0 4.55e-01 100.0% 69.2%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 51.0 4.29e-01 83.1% 66.4%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 48.0 4.21e-01 79.2% 80.5%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.62 44.0 3.97e-01 76.6% 82.7%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 36.0 3.10e-01 71.4% 39.5%
1u00A02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 46.0 4.36e-01 83.1% 75.0%
4gc0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.61 52.0 3.72e-01 98.7% 77.5%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 46.0 3.98e-01 83.1% 77.4%
3rguB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.60 45.0 4.36e-01 81.8% 93.1%
2pusA05 1.10.1740.80 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.59 40.0 3.97e-01 85.7% 66.3%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.59 47.0 4.50e-01 88.3% 94.5%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.57 41.0 3.75e-01 77.9% 75.0%
7tvcA01 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.57 40.0 3.58e-01 76.6% 64.2%
2z4vA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 44.0 3.00e-01 87.0% 39.8%
1gt0D00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.56 33.0 3.28e-01 100.0% 54.4%
6pmiF01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.54 46.0 4.55e-01 94.8% 96.2%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.53 45.0 4.04e-01 97.4% 81.2%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.53 41.0 3.84e-01 84.4% 77.3%
1xl7A01 1.10.275.20 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Choline/Carnitine o-acyltransferase 0.52 41.0 3.75e-01 85.7% 75.7%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3511403 5050.1.1.11 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 0.73 57.0 4.12e-01 83.1% 78.1%
3471897 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.65 50.0 4.12e-01 83.1% 69.3%
4930668 601.30.1.1 alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.65 50.0 4.14e-01 84.4% 73.8%
3841109 192.29.1.293 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › SHCBP_N 0.64 46.0 4.25e-01 76.6% 100.0%
3534202 3602.1.1.16 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › SHCBP_N 0.64 46.0 4.24e-01 76.6% 100.0%
2323977 1198.1.1.0 alpha bundles › BTA121 › BTA121 › BTA121 0.63 55.0 4.64e-01 100.0% 79.4%
4952828 5038.2.1.0 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like 0.63 55.0 4.50e-01 100.0% 76.0%
4025710 3871.1.1.0 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST 0.63 53.0 4.55e-01 93.5% 92.8%
3295653 4268.2.1.0 alpha duplicates or obligate multimers › EspA/CesA-like › EspA chaperone CesA › EspA chaperone CesA 0.63 47.0 4.09e-01 80.5% 85.8%
3253937 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 49.0 4.24e-01 85.7% 80.0%
3940867 632.22.1.67 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › DUF842 0.61 46.0 4.38e-01 83.1% 98.9%
3961367 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.60 45.0 3.74e-01 80.5% 64.3%
3896686 192.8.1.36 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › M_domain 0.60 49.0 4.54e-01 90.9% 97.0%
3741398 632.1.1.8 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › SOG2 0.60 45.0 3.87e-01 83.1% 70.0%
4991039 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 50.0 3.78e-01 97.4% 81.0%
3396895 3788.1.1.0 alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) 0.58 45.0 4.66e-01 98.7% 100.0%
3704822 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.58 51.0 4.02e-01 100.0% 52.1%
3225544 4006.1.1.0 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.53 38.0 3.60e-01 79.2% 100.0%
D3 medium residues 78-168
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4z4qA04 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.60 39.0 3.99e-01 76.9% 67.4%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.58 41.0 3.69e-01 74.7% 90.1%
7p2yd01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.57 44.0 4.38e-01 85.7% 82.8%
5hayA02 1.25.40.440 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain 0.56 35.0 3.71e-01 82.4% 70.9%
3d2eA06 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 38.0 3.51e-01 75.8% 56.6%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.54 43.0 4.16e-01 91.2% 76.4%
5dsgA01 1.10.530.40 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.53 37.0 3.57e-01 72.5% 97.2%
2hi0A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.52 38.0 3.90e-01 76.9% 87.6%
2vixA03 1.20.1280.240 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.51 40.0 3.74e-01 95.6% 68.1%
5xs2B02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.51 38.0 3.42e-01 80.2% 62.1%
1js8A01 1.10.1280.10 Mainly Alpha › Orthogonal Bundle › di-copper center containing domain from catechol oxidase › Di-copper center containing domain from catechol oxidase 0.51 44.0 3.23e-01 100.0% 65.9%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
433161 628.1.1.1 alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD 0.69 55.0 4.82e-01 87.9% 80.6%
4218225 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.61 40.0 3.34e-01 79.1% 39.4%
5083298 4016.1.1.0 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.60 40.0 3.35e-01 79.1% 40.7%
3959880 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.57 39.0 4.02e-01 83.5% 72.2%
5079588 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.56 43.0 4.40e-01 84.6% 97.8%
4625218 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.56 43.0 3.60e-01 85.7% 47.1%
4386395 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.54 42.0 4.10e-01 85.7% 82.0%
4466183 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.52 43.0 4.19e-01 95.6% 80.0%
3616203 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.52 43.0 4.29e-01 96.7% 90.5%
3883744 1188.1.1.1 alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip 0.52 43.0 3.12e-01 93.4% 33.2%
4353495 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.51 39.0 3.22e-01 85.7% 47.9%