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MW749008.1__QYA57401.1__MIFENG_58__00056

Bact-Vir

MW749008.1__QYA57401.1__MIFENG_58__00056

Identity

Accession:
MW749008 ↗
Kingdom:
phage

Quality

87.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-60
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04138.21 best GtrA_DPMS_TM 44.6 2.20e-11 90.0% 46.2%
CATH (63)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2x3mA00 1.25.40.670 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.85 60.0 4.21e-01 75.0% 26.5%
2e62A01 6.10.140.420 Special › Helix non-globular › Helix Hairpins › 0.79 62.0 6.53e-01 85.0% 98.1%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.78 72.0 6.16e-01 100.0% 74.7%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.76 58.0 4.08e-01 81.7% 28.0%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.75 66.0 4.33e-01 100.0% 25.6%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.75 67.0 5.94e-01 100.0% 72.9%
4cc9B00 1.20.5.4730 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.75 60.0 5.07e-01 90.0% 53.1%
3ousA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 61.0 5.46e-01 88.3% 96.3%
5cbgA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 60.0 5.01e-01 90.0% 75.5%
1s8nA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 50.0 5.13e-01 71.7% 82.8%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.72 63.0 4.69e-01 100.0% 38.9%
6wshA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 51.0 5.27e-01 73.3% 89.1%
8ctsB01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 57.0 5.01e-01 85.0% 88.5%
8e9gK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 57.0 5.06e-01 98.3% 59.3%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.72 52.0 4.43e-01 76.7% 49.5%
5i1uA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.71 54.0 3.46e-01 93.3% 16.7%
1ufhA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.70 52.0 3.95e-01 83.3% 34.2%
3lxrF00 1.10.4120.20 Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › 0.70 63.0 4.41e-01 100.0% 60.2%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 60.0 5.33e-01 96.7% 68.2%
6fjxA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.69 54.0 3.53e-01 90.0% 19.2%
5ekcF01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.69 53.0 3.45e-01 90.0% 17.7%
5izdA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.68 53.0 3.43e-01 90.0% 18.3%
5j6bD01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.67 52.0 3.37e-01 90.0% 18.1%
1t90A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.67 54.0 3.50e-01 95.0% 19.3%
2p4vA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.67 48.0 4.44e-01 76.7% 61.8%
5kf6A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.66 53.0 3.49e-01 90.0% 20.8%
1uxtA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.66 49.0 3.17e-01 81.7% 17.6%
3rosA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.65 51.0 3.39e-01 90.0% 19.8%
4i3vA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.65 54.0 3.53e-01 95.0% 20.8%
2hg2A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.65 51.0 3.30e-01 90.0% 18.2%
6adqB01 1.20.810.10 Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C 0.65 55.0 3.35e-01 96.7% 18.2%
2j6lA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.65 51.0 3.26e-01 90.0% 17.3%
4agsB04 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 52.0 3.94e-01 90.0% 38.3%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.64 52.0 4.50e-01 88.3% 57.8%
5vbfA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.64 52.0 3.41e-01 96.7% 19.4%
3pqaB01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.64 55.0 3.63e-01 100.0% 50.4%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 51.0 3.40e-01 88.3% 22.0%
7y9hB01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.64 56.0 3.54e-01 100.0% 80.2%
3r64A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.64 52.0 3.40e-01 96.7% 19.6%
1ez0B01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.64 52.0 3.37e-01 95.0% 18.6%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.64 57.0 4.72e-01 100.0% 65.4%
7w5lA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.63 51.0 3.44e-01 96.7% 22.0%
3vz3A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.63 51.0 3.42e-01 95.0% 21.3%
5b1aC01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 48.0 4.66e-01 96.7% 73.5%
4gzrB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 55.0 5.08e-01 96.7% 75.3%
1euhA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.62 50.0 3.35e-01 95.0% 20.4%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 51.0 4.82e-01 90.0% 75.3%
3rh9A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.62 50.0 3.28e-01 95.0% 19.4%
1jkvA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 51.0 3.49e-01 88.3% 68.0%
4i8qA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.62 51.0 3.29e-01 95.0% 18.9%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 52.0 5.19e-01 95.0% 88.7%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.61 43.0 3.71e-01 78.3% 47.3%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.61 52.0 4.71e-01 96.7% 92.7%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.61 51.0 4.00e-01 95.0% 47.4%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 52.0 4.96e-01 96.7% 85.9%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.60 54.0 5.25e-01 100.0% 97.0%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.60 53.0 3.82e-01 96.7% 37.3%
3frrA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.59 51.0 3.64e-01 98.3% 56.5%
8h6qD01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.58 48.0 3.14e-01 98.3% 69.1%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 47.0 3.32e-01 88.3% 29.2%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.57 52.0 4.48e-01 100.0% 70.3%
4l8eA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 50.0 4.05e-01 96.7% 57.3%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 48.0 3.84e-01 100.0% 83.1%
ECOD (60)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4950752 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.97 93.0 5.48e-01 100.0% 16.4%
4937043 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.96 92.0 5.43e-01 100.0% 16.9%
4974808 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.96 91.0 5.40e-01 100.0% 16.9%
4954814 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.94 87.0 5.21e-01 98.3% 17.2%
4927253 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.93 87.0 5.16e-01 100.0% 16.1%
5043797 3542.1.1.1 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin 0.88 77.0 4.82e-01 93.3% 43.3%
4990358 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.88 78.0 6.96e-01 95.0% 75.0%
3989179 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.86 79.0 5.18e-01 100.0% 97.3%
4963826 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.85 78.0 5.23e-01 100.0% 34.1%
3174987 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.83 75.0 4.69e-01 100.0% 31.9%
4991390 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.83 75.0 6.39e-01 100.0% 73.7%
3806432 1076.1.1.1 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like 0.82 74.0 4.67e-01 100.0% 35.6%
4938848 5069.1.3.131 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF92 0.82 69.0 5.79e-01 91.7% 59.0%
3378999 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.80 71.0 4.61e-01 96.7% 34.3%
3282323 7064.1.1.9 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › GtrA_DPMS_TM 0.80 69.0 5.15e-01 98.3% 39.3%
5065662 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.79 69.0 6.64e-01 98.3% 84.3%
5026366 7064.1.1.1 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.79 67.0 4.74e-01 95.0% 52.8%
3655029 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.78 70.0 4.61e-01 98.3% 37.4%
3663214 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.78 68.0 5.17e-01 95.0% 43.7%
3726035 1076.1.1.1 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like 0.78 69.0 4.48e-01 100.0% 36.9%
3379640 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.78 69.0 4.43e-01 98.3% 31.3%
3973403 5043.1.1.0 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like 0.77 66.0 6.61e-01 95.0% 100.0%
354272 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.77 66.0 5.58e-01 93.3% 85.4%
3341345 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.76 68.0 5.20e-01 98.3% 90.0%
3972086 5067.1.1.1 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ACR_tran 0.75 67.0 4.49e-01 100.0% 33.8%
4927593 136.1.1.0 alpha complex topology › Heme-dependent peroxidases › Heme-dependent peroxidases › Heme-dependent peroxidases 0.74 66.0 4.24e-01 96.7% 41.9%
4937556 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.74 60.0 6.02e-01 100.0% 91.7%
3725609 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.73 62.0 4.34e-01 100.0% 28.8%
5043090 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.73 65.0 5.91e-01 100.0% 80.0%
3215052 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.73 51.0 4.54e-01 76.7% 51.8%
3270860 633.6.1.2 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX 0.71 64.0 4.69e-01 100.0% 71.0%
5065057 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 61.0 4.58e-01 100.0% 87.7%
3737956 601.19.1.18 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Mmc1_C 0.70 61.0 4.29e-01 100.0% 60.0%
3963056 5067.1.1.2 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF 0.69 60.0 4.04e-01 100.0% 26.4%
4189213 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.69 59.0 5.51e-01 98.3% 90.7%
2392956 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.69 54.0 3.57e-01 90.0% 19.8%
3973994 192.4.1.0 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) 0.69 50.0 4.64e-01 76.7% 62.7%
1902479 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.68 53.0 3.53e-01 90.0% 20.5%
4454618 589.1.2.1 alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › TF C-terminus (Pfam 05698) › Trigger_C 0.68 57.0 4.05e-01 93.3% 30.8%
3799156 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.68 53.0 4.97e-01 85.0% 70.3%
4964635 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.68 54.0 3.48e-01 90.0% 18.7%
3487203 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.68 53.0 4.66e-01 83.3% 60.0%
3923696 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.68 53.0 4.61e-01 83.3% 56.7%
3899586 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.67 54.0 3.11e-01 95.0% 8.9%
3617842 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.66 51.0 4.73e-01 96.7% 66.3%
4022741 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.66 57.0 3.77e-01 100.0% 27.7%
4941372 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.65 56.0 5.00e-01 96.7% 96.5%
3963355 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.65 53.0 4.94e-01 88.3% 88.0%
3944665 605.1.1.168 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Aldedh 0.65 50.0 4.10e-01 88.3% 44.3%
4952821 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.64 52.0 3.44e-01 96.7% 20.0%
4018440 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.63 56.0 4.78e-01 96.7% 68.4%
3965195 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.63 51.0 3.53e-01 95.0% 25.0%
1889963 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.63 50.0 3.25e-01 90.0% 19.8%
1903556 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.62 51.0 3.39e-01 96.7% 21.1%
3282601 150.8.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE 0.62 55.0 3.84e-01 100.0% 68.7%
4990946 5058.1.1.102 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › DUF1634 0.61 51.0 4.59e-01 98.3% 78.9%
5059005 5068.1.1.0 alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 0.61 52.0 3.83e-01 100.0% 35.4%
5002748 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.61 54.0 5.02e-01 100.0% 90.7%
4960850 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.57 48.0 4.88e-01 98.3% 98.3%
2890670 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.56 48.0 3.70e-01 100.0% 41.7%
D2 medium residues 61-118
PDB
Domain cluster: representative
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3juiA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.78 57.0 4.07e-01 86.2% 26.4%
2e62A01 6.10.140.420 Special › Helix non-globular › Helix Hairpins › 0.78 61.0 6.41e-01 89.7% 98.1%
3bk2A03 3.10.20.580 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.76 58.0 4.92e-01 89.7% 49.5%
4jd9G00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.74 61.0 4.79e-01 98.3% 43.3%
2id3A01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.73 48.0 5.14e-01 82.8% 79.6%
3of4A00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.73 54.0 3.71e-01 82.8% 22.7%
1kf6D00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.73 63.0 4.98e-01 98.3% 49.6%
1icrA00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.72 63.0 4.24e-01 98.3% 64.8%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.71 61.0 5.71e-01 100.0% 77.0%
4zi3D00 1.20.1520.10 Mainly Alpha › Up-down Bundle › Adp-ribosylation factor-like protein 2-binding protein fold › ADP-ribosylation factor-like 2-binding protein, domain 0.71 63.0 4.85e-01 100.0% 55.5%
4ex8A00 3.40.1790.10 Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain 0.70 56.0 3.50e-01 89.7% 16.6%
1gvnA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.68 57.0 4.93e-01 91.4% 81.6%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.68 60.0 4.25e-01 100.0% 32.4%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.68 45.0 4.21e-01 74.1% 56.3%
2q0yA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.68 48.0 3.74e-01 81.0% 32.6%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.68 48.0 4.47e-01 75.9% 60.6%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.67 54.0 4.83e-01 100.0% 61.5%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.66 50.0 4.92e-01 81.0% 80.6%
1k6yA01 1.10.10.200 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain 0.66 34.0 3.78e-01 94.8% 60.9%
4iw9A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.66 47.0 3.79e-01 75.9% 43.4%
1b48A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 48.0 3.97e-01 81.0% 49.5%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.65 52.0 3.88e-01 87.9% 43.4%
2zb9A01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.65 42.0 4.45e-01 70.7% 78.0%
1cf7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 49.0 4.50e-01 86.2% 75.6%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.64 54.0 5.18e-01 96.6% 80.9%
2a2cA03 1.20.1440.340 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.64 52.0 3.91e-01 96.6% 37.0%
2gsqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 49.0 3.97e-01 82.8% 51.9%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.64 52.0 4.76e-01 96.6% 74.4%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.62 52.0 4.06e-01 96.6% 43.5%
2keyA00 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.62 45.0 3.73e-01 81.0% 42.9%
4x28A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.61 47.0 3.85e-01 86.2% 51.3%
2i53A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.61 48.0 3.94e-01 98.3% 45.9%
3k59A06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.59 44.0 4.80e-01 84.5% 100.0%
6f1eA01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.58 48.0 3.67e-01 100.0% 38.8%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 50.0 4.20e-01 100.0% 59.8%
4dokA01 3.50.70.10 Alpha Beta › 3-Layer(bba) Sandwich › Chalcone isomerase › 0.57 44.0 3.42e-01 93.1% 45.2%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 50.0 4.73e-01 100.0% 87.0%
6ygiB01 1.10.4090.10 Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus 0.54 47.0 3.56e-01 100.0% 63.7%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4515894 5043.1.1.0 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like 0.85 73.0 7.46e-01 100.0% 98.2%
4949603 3718.1.1.34 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › PF26161 0.83 74.0 6.44e-01 100.0% 65.9%
3515411 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.79 66.0 4.50e-01 98.3% 26.3%
3999314 5058.1.1.35 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › EMC6 0.79 70.0 6.45e-01 100.0% 77.3%
3895581 10.12.1.0 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.76 55.0 4.30e-01 79.3% 36.0%
3589830 5043.2.1.8 extended segments › Sensor proteins transmembrane domains › NarQ transmembrane domain › NarQ transmembrane domain › DUF5592 0.76 69.0 6.46e-01 100.0% 87.1%
3192559 148.1.3.216 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › DUF7069 0.76 58.0 5.12e-01 87.9% 56.5%
3718561 3843.1.1.11 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DGF-1_C 0.75 64.0 4.02e-01 98.3% 18.0%
4149728 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.75 67.0 6.00e-01 100.0% 76.2%
5028558 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.74 63.0 5.37e-01 100.0% 58.0%
3993361 622.4.1.41 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › DUF7753 0.73 61.0 6.01e-01 100.0% 95.4%
5055977 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.72 62.0 5.25e-01 100.0% 58.0%
3667014 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.72 57.0 3.34e-01 89.7% 11.0%
3400382 3877.1.1.1 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP 0.72 59.0 3.82e-01 100.0% 19.6%
1147932 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.71 59.0 5.19e-01 96.6% 62.4%
2674763 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.71 61.0 5.66e-01 100.0% 76.0%
3719414 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.69 56.0 5.35e-01 94.8% 75.7%
3952366 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.69 54.0 5.45e-01 100.0% 88.3%
3214934 5001.1.1.54 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srbc 0.68 59.0 3.80e-01 100.0% 20.7%
3539738 10.12.1.1 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › cNMP_binding 0.66 47.0 3.10e-01 74.1% 19.6%
3617842 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.66 52.0 4.80e-01 93.1% 66.3%
3950890 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.66 57.0 5.64e-01 96.6% 100.0%
3392541 104.1.1.1 alpha duplicates or obligate multimers › TFIIA, alpha-helical domain › TFIIA, alpha-helical domain › TFIIA, alpha-helical domain › TFIIA_gamma_N 0.64 45.0 4.65e-01 84.5% 83.6%
4086475 3755.3.1.466 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CC_BshC 0.63 56.0 4.12e-01 100.0% 40.0%
3923696 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.58 47.0 4.21e-01 96.6% 64.4%
3581366 74.1.1.0 beta duplicates or obligate multimers › Transcription factor IIA (TFIIA), beta-barrel domain › Transcription factor IIA (TFIIA), beta-barrel domain › Transcription factor IIA (TFIIA), beta-barrel domain 0.52 43.0 2.62e-01 100.0% 35.1%