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MW824375.1QZI90440.1MYOV003v1_p0116__00116

Bact-Vir

MW824375.1__QZI90440.1__MYOV003v1_p0116__00116

Identity

Accession:: MW824375 ↗
Kingdom:: phage

Quality

68.6 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Pantevenvirales› Ackermannviridae› Vibrio_phage_207E48.1

TaxID: 2859310

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 159-230

PDB

Domain cluster: representative

CATH (40)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3cuqA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.75	61.0	5.92e-01	91.7%	79.0%
2w43A02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.71	51.0	5.59e-01	75.0%	98.2%
2ymmA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.71	51.0	5.10e-01	75.0%	79.5%
3umbA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.70	50.0	4.86e-01	75.0%	94.9%
3nbiA01	1.10.8.1020	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain	0.70	43.0	4.70e-01	95.8%	77.6%
6qm7A00	3.60.20.10	Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain	0.69	52.0	3.59e-01	81.9%	62.3%
2no4A02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.68	48.0	4.81e-01	75.0%	98.7%
5xs2B02	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.68	57.0	4.76e-01	95.8%	54.5%
3umgA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.68	49.0	4.93e-01	76.4%	90.1%
1yg2A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	57.0	5.60e-01	94.4%	92.4%
3mwmA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	57.0	5.65e-01	94.4%	94.7%
4ye6A02	1.10.10.2420	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A ›	0.66	49.0	5.24e-01	90.3%	98.3%
3solA00	1.20.58.1630	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chaperone lipoprotein PulS/OutS	0.65	56.0	5.29e-01	100.0%	89.0%
1rypD00	3.60.20.10	Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain	0.65	51.0	3.58e-01	86.1%	59.3%
1rypA00	3.60.20.10	Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain	0.65	52.0	3.61e-01	87.5%	61.3%
2xubA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	54.0	5.05e-01	93.1%	78.3%
7lxuE01	3.60.20.10	Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain	0.65	52.0	3.70e-01	87.5%	66.4%
3unbF00	3.60.20.10	Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain	0.64	51.0	3.54e-01	87.5%	59.4%
1zp2A02	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.64	49.0	4.37e-01	94.4%	56.2%
5fmgG00	3.60.20.10	Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain	0.64	51.0	3.62e-01	87.5%	61.2%
2doeA00	1.10.10.440	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain	0.63	49.0	4.73e-01	94.4%	73.5%
6qm7J00	3.60.20.10	Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain	0.63	47.0	3.44e-01	80.6%	64.7%
1l3eB00	1.20.1020.10	Mainly Alpha › Up-down Bundle › CREB-binding Protein; Chain A › TAZ domain	0.63	38.0	3.42e-01	88.9%	42.6%
1rypL00	3.60.20.10	Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain	0.62	49.0	3.54e-01	87.5%	65.1%
1rypK00	3.60.20.10	Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain	0.62	49.0	3.61e-01	87.5%	95.5%
6muwM00	3.60.20.10	Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain	0.61	48.0	3.46e-01	86.1%	68.1%
3fhnA05	1.10.10.2270	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Dsl1p vesicle tethering complex, Tip20p subunit, domain E	0.61	47.0	4.87e-01	93.1%	89.6%
2hszA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.59	48.0	4.79e-01	91.7%	89.3%
1dp3A00	1.10.10.450	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › TraM protein, DNA-binding	0.57	38.0	4.18e-01	100.0%	89.1%
6aveA01	1.10.287.770	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like	0.57	37.0	3.76e-01	76.4%	66.2%
2be4A02	1.10.238.10	Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand	0.55	48.0	4.33e-01	100.0%	83.2%
1vpdA02	1.10.1040.10	Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	0.55	47.0	3.93e-01	97.2%	87.0%
4y0bA00	1.10.1780.10	Mainly Alpha › Orthogonal Bundle › Double Clp-N motif › Clp, N-terminal domain	0.54	38.0	3.14e-01	75.0%	76.4%
1cukA02	1.10.150.20	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain	0.53	40.0	3.95e-01	97.2%	77.6%
3ckdA02	1.20.58.360	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines	0.53	39.0	3.34e-01	80.6%	85.5%
2vk9A04	1.10.274.80	Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 ›	0.52	39.0	3.54e-01	90.3%	57.7%
4ielA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.51	37.0	3.15e-01	91.7%	47.4%
1oc2A02	3.90.25.10	Alpha Beta › Alpha-Beta Complex › UDP-galactose 4-epimerase; domain 1 › UDP-galactose 4-epimerase, domain 1	0.51	43.0	4.22e-01	95.8%	97.4%
4s3mB02	1.10.1040.10	Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	0.51	44.0	3.93e-01	100.0%	68.9%
2i0mA01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.50	42.0	3.71e-01	91.7%	77.4%

ECOD (68)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3797632	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.77	61.0	6.31e-01	90.3%	95.4%
4032499	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.76	63.0	6.27e-01	91.7%	88.0%
3500575	101.1.1.21 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5	0.76	57.0	6.14e-01	88.9%	98.3%
4946290	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.76	59.0	6.18e-01	93.1%	93.8%
3932319	101.1.1.21 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5	0.74	55.0	5.06e-01	83.3%	61.1%
5027755	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.74	54.0	5.23e-01	91.7%	70.0%
3622919	101.1.1.21 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5	0.73	63.0	6.10e-01	95.8%	88.7%
4976304	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.73	65.0	6.33e-01	100.0%	96.2%
3535212	101.1.1.65 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_4	0.73	61.0	5.69e-01	91.7%	96.7%
3839204	2.21.1.3 ↗	beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605	0.73	65.0	4.83e-01	100.0%	46.7%
2796011	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.73	56.0	5.02e-01	88.9%	60.0%
4010838	7000.1.1.1 ↗	alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › HTH_OrfB_IS605	0.73	63.0	4.98e-01	95.8%	54.5%
3986141	7000.1.1.1 ↗	alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › HTH_OrfB_IS605	0.72	63.0	5.72e-01	95.8%	83.2%
4933807	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	62.0	5.91e-01	95.8%	95.3%
5065106	7000.1.1.1 ↗	alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › HTH_OrfB_IS605	0.72	62.0	6.01e-01	95.8%	96.2%
1699723	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	59.0	5.63e-01	91.7%	77.4%
3255275	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.71	53.0	5.70e-01	86.1%	96.7%
5045083	101.1.10.0 ↗	alpha arrays › HTH › HTH › Cyclin-like	0.71	59.0	4.39e-01	93.1%	40.5%
5002913	2.21.1.3 ↗	beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605	0.71	61.0	4.61e-01	95.8%	48.2%
5003363	7000.1.1.1 ↗	alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › HTH_OrfB_IS605	0.71	61.0	5.66e-01	95.8%	85.6%
3876674	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.70	59.0	5.47e-01	91.7%	94.4%
3250201	101.1.1.21 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5	0.70	55.0	5.78e-01	90.3%	96.9%
3962321	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.70	61.0	5.50e-01	100.0%	94.0%
3709807	2003.1.9.1 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF	0.70	51.0	3.30e-01	79.2%	18.3%
4979742	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.68	54.0	5.25e-01	97.2%	77.5%
5082325	3705.1.1.3 ↗	alpha arrays › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › Phage_holin_6_1	0.68	55.0	5.62e-01	93.1%	98.6%
4238004	102.1.1.0 ↗	alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like	0.67	51.0	5.24e-01	81.9%	87.1%
2075033	3787.1.1.0 ↗	alpha bundles › HAD superfamily helical bundle insertion domain	0.66	50.0	4.92e-01	81.9%	97.5%
4983336	2006.1.1.18 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2	0.65	57.0	4.00e-01	98.6%	76.2%
1322519	101.1.2.188 ↗	alpha arrays › HTH › HTH › winged helix domain › Roquin_1_2-like_ROQ	0.65	52.0	4.76e-01	90.3%	66.3%
3682832	210.1.1.1 ↗	a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome	0.65	51.0	4.01e-01	86.1%	90.3%
3727365	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.65	55.0	3.85e-01	94.4%	72.8%
4556297	210.1.1.1 ↗	a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome	0.64	51.0	3.75e-01	87.5%	69.7%
4092408	102.1.1.119 ↗	alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DUF4332	0.64	51.0	5.07e-01	86.1%	82.7%
4193687	101.1.10.1 ↗	alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N	0.64	56.0	3.75e-01	100.0%	35.2%
4972578	109.23.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › C-terminal domain in vacuolar protein sorting-associated protein 54 › C-terminal domain in vacuolar protein sorting-associated protein 54	0.64	53.0	4.79e-01	91.7%	66.7%
5025666	7000.1.1.4 ↗	alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › PF27234	0.64	55.0	4.34e-01	98.6%	48.4%
3327321	3843.1.1.0 ↗	alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K	0.63	44.0	4.09e-01	72.2%	72.2%
5051738	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.62	50.0	5.09e-01	94.4%	94.3%
3849734	101.1.1.65 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_4	0.62	51.0	4.87e-01	91.7%	95.3%
5005257	2.21.1.0 ↗	beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB)	0.62	53.0	4.10e-01	98.6%	44.1%
3353701	101.1.1.65 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_4	0.62	52.0	4.70e-01	95.8%	86.0%
3684676	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.62	50.0	4.40e-01	95.8%	95.8%
3316706	148.1.3.0 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain	0.61	42.0	3.82e-01	72.2%	65.0%
4934293	4993.1.1.0 ↗	extended segments › Glu-tRNAGln amidotransferase C subunit › Glu-tRNAGln amidotransferase C subunit › Glu-tRNAGln amidotransferase C subunit	0.61	50.0	4.85e-01	93.1%	82.5%
3650360	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.61	50.0	4.36e-01	95.8%	96.7%
3348391	101.1.1.65 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_4	0.60	50.0	4.61e-01	97.2%	85.0%
3857499	101.1.1.65 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_4	0.60	50.0	4.60e-01	97.2%	94.0%
4872217	262.1.1.1 ↗	a+b complex topology › Nitric oxide (NO) synthase oxygenase domain › Nitric oxide (NO) synthase oxygenase domain › Nitric oxide (NO) synthase oxygenase domain › NO_synthase	0.59	43.0	2.92e-01	76.4%	70.7%
1815422	566.1.1.3 ↗	alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Pneumo_ncap	0.59	50.0	3.64e-01	100.0%	82.4%
3798489	164.1.1.0 ↗	alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II	0.59	52.0	4.54e-01	100.0%	74.5%
3477766	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.58	49.0	4.70e-01	94.4%	80.0%
4982078	2008.1.1.59 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1	0.58	47.0	3.19e-01	91.7%	47.2%
3890334	101.1.1.65 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_4	0.58	48.0	4.52e-01	97.2%	95.8%
3777847	149.1.1.1 ↗	alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450	0.58	46.0	2.89e-01	93.1%	66.9%
3620304	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.58	47.0	4.58e-01	93.1%	92.5%
3401673	101.1.1.65 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_4	0.58	48.0	4.44e-01	95.8%	90.5%
3706707	592.2.1.0 ↗	alpha arrays › PWI domain-like › YugE-like › YugE-like	0.57	46.0	4.25e-01	91.7%	77.9%
4411256	2004.1.1.80 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Cytidylate_kin	0.57	48.0	3.41e-01	94.4%	43.6%
3936678	164.1.1.0 ↗	alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II	0.55	46.0	4.46e-01	93.1%	90.0%
5006044	206.1.1.268 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF6206	0.54	44.0	2.97e-01	88.9%	22.4%
3250617	140.1.1.4 ↗	alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2	0.52	43.0	2.97e-01	91.7%	27.2%
3971841	3552.1.1.1 ↗	alpha arrays › Pfam family PF09836 N-terminal domain › Pfam family PF09836 N-terminal domain › Pfam family PF09836 N-terminal domain › DUF2063	0.52	37.0	3.18e-01	76.4%	47.2%
3578694	192.5.1.2 ↗	alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › Tiam_CC_Ex	0.52	41.0	4.07e-01	86.1%	84.0%
5073394	148.1.3.20 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_2	0.51	41.0	3.84e-01	88.9%	83.3%
3597337	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.51	37.0	2.85e-01	93.1%	32.0%
3378485	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.51	44.0	3.04e-01	100.0%	55.8%
5028077	601.7.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain	0.50	46.0	3.95e-01	100.0%	79.1%

D2 high residues 257-343

PDB

Domain cluster: rep: MN718199.1__QGZ16141.1__Kuja_1500__00150__D286-371

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF04545.23 best	Sigma70_r4	59.9	1.90e-16	57.5%	96.0%

CATH (41)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5fgmA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.91	62.0	7.19e-01	70.1%	95.4%
1rp3G02	1.20.140.160	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain	0.89	63.0	5.25e-01	73.6%	45.8%
4nqwA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.88	62.0	7.24e-01	72.4%	98.4%
1s7oB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.85	60.0	5.55e-01	73.6%	60.0%
3hugA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.85	64.0	6.69e-01	78.2%	85.0%
3p7nA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.81	62.0	6.78e-01	86.2%	95.8%
2q0oA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.79	51.0	5.76e-01	72.4%	85.1%
1l3lA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.77	50.0	5.81e-01	75.9%	92.1%
5f64A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	58.0	6.22e-01	86.2%	96.0%
2dbbB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.73	46.0	5.52e-01	77.0%	100.0%
6cc0A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	51.0	5.72e-01	83.9%	91.4%
2ia0A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	45.0	5.40e-01	74.7%	100.0%
1a04A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	55.0	5.71e-01	90.8%	86.3%
5z4zC00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	49.0	4.90e-01	72.4%	75.0%
2esnA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	50.0	4.99e-01	77.0%	77.5%
4gvpA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.66	57.0	4.25e-01	92.0%	51.9%
3onqA03	1.10.10.2840	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain	0.66	56.0	4.87e-01	92.0%	67.2%
1p4wA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	55.0	5.52e-01	93.1%	88.5%
2om6A02	1.10.150.400	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 ›	0.66	34.0	3.54e-01	75.9%	53.2%
1aisB02	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.64	47.0	4.65e-01	77.0%	77.7%
4rocA01	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.64	45.0	4.31e-01	73.6%	72.8%
2e18A00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.64	46.0	3.28e-01	75.9%	89.5%
2mqkA00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.63	37.0	4.16e-01	72.4%	76.9%
4h03A02	3.90.176.10	Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1	0.62	51.0	3.90e-01	90.8%	79.7%
2qwwC00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	42.0	3.69e-01	73.6%	71.7%
4rgxB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.60	52.0	4.60e-01	98.9%	96.3%
2rdpA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	49.0	4.19e-01	89.7%	89.3%
3py8A04	1.10.150.20	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain	0.58	49.0	4.22e-01	94.3%	95.1%
4pxoA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.58	47.0	4.09e-01	87.4%	87.8%
7e4mA01	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.57	45.0	3.21e-01	85.1%	81.2%
1sfxB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.56	39.0	3.74e-01	72.4%	66.3%
2bnmA01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.56	35.0	3.69e-01	78.2%	71.6%
4em2A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.56	49.0	4.14e-01	100.0%	92.0%
2go7A02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.54	37.0	4.15e-01	72.4%	98.5%
3fbzA01	1.20.58.800	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.53	38.0	3.66e-01	88.5%	64.7%
3cecA00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.52	44.0	4.43e-01	98.9%	90.1%
1b0nA00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.52	37.0	3.50e-01	83.9%	63.1%
3bj6B00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.51	43.0	3.74e-01	100.0%	94.0%
3ddlA00	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.51	41.0	3.05e-01	90.8%	81.3%
3emlA01	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.50	37.0	2.67e-01	80.5%	84.7%
2fxaA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.50	41.0	3.49e-01	94.3%	87.2%

ECOD (93)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4146353	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.95	67.0	7.00e-01	72.4%	80.0%
4233279	142.1.1.0 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors	0.93	65.0	4.55e-01	72.4%	27.1%
4497189	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.93	63.0	7.39e-01	70.1%	96.9%
4237551	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.93	66.0	6.41e-01	73.6%	68.4%
4032673	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.92	65.0	4.50e-01	72.4%	26.1%
3291331	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.92	66.0	6.88e-01	73.6%	81.2%
4238054	142.1.1.0 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors	0.92	66.0	4.56e-01	73.6%	26.5%
4663875	142.1.1.0 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors	0.92	66.0	4.57e-01	73.6%	27.1%
None	—		0.92	66.0	4.55e-01	73.6%	26.5%
4388780	101.1.1.30 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4	0.92	63.0	5.19e-01	71.3%	44.1%
3587538	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.92	64.0	7.22e-01	71.3%	91.2%
4577850	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.91	65.0	6.21e-01	73.6%	67.7%
4165188	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.91	65.0	6.64e-01	73.6%	76.5%
3282225	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.91	65.0	6.80e-01	73.6%	83.7%
3284051	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.91	63.0	7.28e-01	71.3%	96.9%
3961841	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.91	62.0	6.92e-01	70.1%	90.0%
4520564	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.91	60.0	6.30e-01	74.7%	73.8%
3587471	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.91	66.0	5.71e-01	74.7%	66.7%
4160122	101.1.1.30 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4	0.90	65.0	5.22e-01	73.6%	43.3%
3288090	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.90	64.0	7.15e-01	73.6%	92.9%
3959929	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.90	64.0	6.71e-01	73.6%	81.2%
4202221	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.90	62.0	7.09e-01	71.3%	94.1%
3163616	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.90	64.0	6.25e-01	73.6%	69.1%
3959252	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.90	60.0	7.24e-01	72.4%	100.0%
4439853	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.90	64.0	7.11e-01	73.6%	92.9%
3587755	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.90	61.0	5.22e-01	70.1%	59.2%
3288971	101.1.1.30 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4	0.90	63.0	5.10e-01	72.4%	43.3%
4303963	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.89	64.0	6.87e-01	73.6%	85.3%
3284469	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.89	64.0	6.86e-01	73.6%	90.7%
4205790	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.89	63.0	6.63e-01	73.6%	81.2%
3971395	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.89	63.0	6.73e-01	72.4%	88.0%
4279016	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.89	63.0	6.64e-01	73.6%	83.7%
3971665	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.89	66.0	7.13e-01	77.0%	93.3%
3908306	101.1.1.101 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_40	0.89	54.0	6.49e-01	72.4%	90.0%
3972638	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.89	63.0	7.28e-01	73.6%	98.5%
3284011	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.89	63.0	7.02e-01	73.6%	92.9%
4372550	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.88	63.0	6.25e-01	73.6%	74.4%
4530655	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.88	62.0	5.89e-01	72.4%	65.0%
3283863	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.88	63.0	6.23e-01	73.6%	72.2%
3284461	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.88	63.0	4.36e-01	73.6%	26.4%
3955987	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.88	62.0	6.02e-01	72.4%	66.3%
3972713	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.88	63.0	6.09e-01	73.6%	68.4%
3967026	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.88	61.0	6.55e-01	71.3%	84.0%
4486973	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.88	63.0	6.40e-01	73.6%	76.5%
3959868	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.88	62.0	6.67e-01	72.4%	86.7%
2817645	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.87	62.0	6.53e-01	73.6%	83.7%
3971149	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.87	62.0	6.51e-01	73.6%	85.0%
3284984	142.1.1.0 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors	0.87	62.0	4.31e-01	73.6%	26.0%
3969325	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.87	62.0	6.89e-01	73.6%	95.7%
3967748	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.87	61.0	6.22e-01	72.4%	75.3%
4043241	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.87	62.0	6.49e-01	73.6%	81.2%
None	—		0.87	61.0	5.67e-01	73.6%	60.0%
3589532	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.87	61.0	5.84e-01	72.4%	78.6%
3973360	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.86	61.0	6.80e-01	73.6%	95.7%
None	—		0.86	62.0	5.72e-01	73.6%	61.0%
4140444	101.1.1.26 ↗	alpha arrays › HTH › HTH › Three-helical HTH › UPF0122	0.86	62.0	5.60e-01	73.6%	58.2%
3289947	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.86	59.0	6.18e-01	77.0%	76.2%
4289285	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.86	64.0	6.36e-01	78.2%	74.4%
None	—		0.86	62.0	5.60e-01	73.6%	58.2%
3951829	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.86	65.0	6.63e-01	78.2%	80.0%
4454772	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.86	59.0	6.71e-01	70.1%	96.9%
3961604	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.86	60.0	5.72e-01	72.4%	64.0%
None	—		0.86	61.0	5.56e-01	73.6%	58.2%
4603338	101.1.1.31 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4	0.85	59.0	6.54e-01	71.3%	92.9%
4470607	101.1.1.26 ↗	alpha arrays › HTH › HTH › Three-helical HTH › UPF0122	0.85	61.0	5.44e-01	73.6%	55.7%
4148347	101.1.1.26 ↗	alpha arrays › HTH › HTH › Three-helical HTH › UPF0122	0.85	61.0	5.69e-01	73.6%	61.5%
2464007	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.85	59.0	6.73e-01	71.3%	95.5%
4336182	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.85	62.0	6.14e-01	75.9%	74.4%
4037682	101.1.1.26 ↗	alpha arrays › HTH › HTH › Three-helical HTH › UPF0122	0.85	60.0	5.73e-01	73.6%	64.0%
4456068	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.85	64.0	6.05e-01	78.2%	69.0%
4304581	101.1.1.26 ↗	alpha arrays › HTH › HTH › Three-helical HTH › UPF0122	0.84	60.0	5.83e-01	73.6%	68.1%
3974736	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.84	63.0	6.43e-01	78.2%	81.2%
5028064	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.84	50.0	4.25e-01	70.1%	40.0%
3959876	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.84	63.0	5.97e-01	78.2%	69.0%
3279596	142.1.1.0 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors	0.83	61.0	4.58e-01	77.0%	34.7%
4175748	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.83	66.0	6.89e-01	82.8%	97.5%
3286778	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.83	59.0	6.55e-01	73.6%	91.4%
3573627	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.83	62.0	5.40e-01	78.2%	56.0%
3279339	142.1.1.0 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors	0.82	60.0	4.58e-01	77.0%	35.7%
4683324	101.1.1.26 ↗	alpha arrays › HTH › HTH › Three-helical HTH › UPF0122	0.82	61.0	5.58e-01	78.2%	60.9%
3616846	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.82	51.0	6.01e-01	77.0%	91.7%
3977260	101.1.1.39 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Phage_antitermQ	0.81	64.0	5.62e-01	81.6%	61.7%
3283374	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.81	61.0	5.97e-01	82.8%	72.6%
None	—		0.81	61.0	5.57e-01	78.2%	62.4%
4683276	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.80	61.0	5.87e-01	78.2%	72.6%
None	—		0.80	60.0	5.85e-01	78.2%	71.6%
149489	101.1.1.95 ↗	alpha arrays › HTH › HTH › Three-helical HTH › PhyR_sigma-like	0.79	54.0	5.62e-01	70.1%	76.2%
4396640	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.78	61.0	5.40e-01	89.7%	59.2%
3284292	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.78	57.0	5.64e-01	81.6%	73.3%
2813289	101.1.1.71 ↗	alpha arrays › HTH › HTH › Three-helical HTH › KORA	0.77	53.0	5.16e-01	71.3%	96.9%
5023952	101.1.2.888 ↗	alpha arrays › HTH › HTH › winged helix domain › Sigma70_r4_2	0.76	56.0	6.18e-01	78.2%	94.3%
3286659	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.74	56.0	6.18e-01	80.5%	97.1%
3998881	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.69	50.0	5.19e-01	80.5%	82.5%

D3 high residues 357-404

PDB

Domain cluster: representative

CATH (96)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2x48A00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.94	69.0	6.60e-01	79.2%	68.5%
6uglB02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.94	75.0	6.99e-01	85.4%	70.7%
6v7xB02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.94	77.0	7.25e-01	87.5%	75.0%
3p7nA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.92	85.0	7.28e-01	100.0%	66.7%
4go1A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.92	77.0	7.37e-01	89.6%	85.2%
5f64A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.91	81.0	6.90e-01	100.0%	62.7%
2q0oA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.91	80.0	7.10e-01	95.8%	68.7%
2o8xA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.91	83.0	7.59e-01	100.0%	78.7%
3ulqB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.91	78.0	7.28e-01	93.8%	77.6%
5fgmA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.90	82.0	7.33e-01	100.0%	73.8%
1gdtB03	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.90	67.0	6.95e-01	79.2%	84.4%
6jqsA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.90	78.0	6.93e-01	95.8%	68.7%
2w48B01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.90	76.0	7.44e-01	91.7%	90.4%
1a04A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.89	82.0	6.77e-01	100.0%	60.0%
1s7oB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.89	82.0	6.20e-01	100.0%	45.7%
4gvpA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.89	78.0	5.03e-01	100.0%	22.8%
4nqwA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.89	80.0	7.25e-01	100.0%	75.0%
3vfzB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.89	80.0	7.31e-01	100.0%	82.5%
2lfwA01	1.20.140.160	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain	0.89	81.0	5.63e-01	100.0%	37.6%
1rp3G02	1.20.140.160	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain	0.89	80.0	5.58e-01	100.0%	33.8%
3hugA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.88	79.0	6.62e-01	100.0%	60.0%
6g1dA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.87	71.0	5.82e-01	87.5%	51.2%
1r71A01	1.10.10.730	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › KorB DNA-binding domain	0.87	67.0	6.38e-01	85.4%	71.4%
3t0yA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.86	77.0	7.17e-01	100.0%	80.0%
1l3lA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.86	74.0	6.74e-01	95.8%	73.0%
2r0qC02	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.86	67.0	6.37e-01	83.3%	87.3%
5xsoA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.86	77.0	6.57e-01	100.0%	63.2%
5y2vC01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.86	69.0	5.65e-01	89.6%	49.4%
6cc0A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.85	77.0	6.75e-01	100.0%	68.6%
3c57B00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.85	69.0	6.92e-01	91.7%	87.8%
1k78A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.85	70.0	6.22e-01	89.6%	65.2%
1tc3C00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.84	67.0	6.58e-01	85.4%	80.4%
3zh9B03	1.20.272.10	Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 ›	0.84	67.0	4.89e-01	87.5%	33.3%
4izzB02	1.10.10.1680	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › HetR, N-terminal DNA-binding domain	0.84	67.0	6.02e-01	89.6%	64.7%
3szpA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.83	69.0	5.61e-01	93.8%	49.4%
3iuoA00	1.10.10.1390	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › ATP-dependent DNA helicase RecQ	0.83	68.0	5.20e-01	91.7%	40.4%
3onqA03	1.10.10.2840	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain	0.83	73.0	5.30e-01	100.0%	41.2%
1p4wA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.82	72.0	5.95e-01	100.0%	57.5%
2elhA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.82	66.0	5.89e-01	89.6%	63.6%
2esnA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.82	70.0	5.69e-01	95.8%	52.8%
5z4zC00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.81	68.0	5.59e-01	93.8%	52.3%
2e7xA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.81	67.0	6.61e-01	91.7%	92.3%
2w7nA00	1.10.10.2690	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A ›	0.81	70.0	5.65e-01	100.0%	56.4%
4ha8A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.80	65.0	5.94e-01	89.6%	74.6%
3hhgE01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.80	66.0	5.46e-01	95.8%	51.1%
4nvsA00	3.10.180.10	Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1	0.79	62.0	4.27e-01	85.4%	52.9%
2lvsA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.79	63.0	6.01e-01	89.6%	76.8%
4pcqA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.79	62.0	6.15e-01	85.4%	90.0%
3fxqB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.79	65.0	5.34e-01	95.8%	50.0%
2dbbB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.77	64.0	6.22e-01	95.8%	87.3%
1s3jA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.77	63.0	5.77e-01	91.7%	71.9%
2ia0A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.77	63.0	6.14e-01	93.8%	87.0%
2llkA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.76	58.0	6.11e-01	85.4%	97.6%
3tgnB02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.76	61.0	5.65e-01	91.7%	71.4%
2e18A00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.76	68.0	4.21e-01	100.0%	43.0%
1r1uB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.75	63.0	5.10e-01	95.8%	52.7%
3dv8A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.75	60.0	5.14e-01	89.6%	64.1%
4ijaA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.75	59.0	5.47e-01	89.6%	71.4%
5dukB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	58.0	5.24e-01	89.6%	62.7%
2m8gX00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.74	57.0	5.05e-01	85.4%	60.0%
3k9tA03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	62.0	5.72e-01	100.0%	84.8%
2x4hA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	59.0	4.37e-01	91.7%	38.8%
6sdkA01	1.10.10.2830	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A ›	0.73	59.0	4.78e-01	91.7%	47.4%
3nrvB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.73	60.0	4.54e-01	97.9%	39.5%
2gxgA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.73	62.0	4.50e-01	97.9%	35.7%
4wcgA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.73	58.0	5.40e-01	89.6%	73.8%
2cfxA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	59.0	5.85e-01	93.8%	94.0%
6az6A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	58.0	5.04e-01	89.6%	88.0%
2cobA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.72	56.0	5.78e-01	89.6%	95.5%
1b9mB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	61.0	4.91e-01	97.9%	54.5%
4o5vA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	58.0	5.12e-01	89.6%	64.8%
2lvsA02	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.71	54.0	5.44e-01	85.4%	83.7%
2a6cA00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.71	55.0	4.77e-01	85.4%	53.9%
1k6yA01	1.10.10.200	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain	0.71	49.0	5.05e-01	72.9%	80.4%
6rnzA00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.71	53.0	4.82e-01	89.6%	59.1%
1sfxB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	57.0	4.57e-01	93.8%	70.2%
2hyjA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.70	49.0	5.04e-01	75.0%	95.7%
2yveB00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.70	54.0	3.79e-01	89.6%	33.1%
2o38A01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.70	54.0	4.93e-01	85.4%	63.1%
2k9qA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.70	52.0	5.64e-01	89.6%	95.0%
3mklA00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.70	53.0	4.15e-01	83.3%	43.3%
3cuqB03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	54.0	4.82e-01	91.7%	60.9%
3ecoB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	57.0	4.30e-01	97.9%	40.3%
3d0sA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	54.0	4.63e-01	89.6%	71.2%
3op9A01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.67	52.0	4.61e-01	85.4%	58.8%
3i71B00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	46.0	4.38e-01	72.9%	60.3%
5cz2G00	1.10.10.200	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain	0.66	45.0	4.76e-01	72.9%	87.8%
3cuoD00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	54.0	4.51e-01	97.9%	53.2%
2y75A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	52.0	3.95e-01	89.6%	37.6%
3mczA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	52.0	4.50e-01	93.8%	56.1%
7vjmB01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.64	50.0	4.61e-01	91.7%	65.6%
3ni7A00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.63	48.0	3.40e-01	89.6%	47.1%
3cecA00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.62	49.0	4.07e-01	91.7%	75.8%
8dtqA01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.61	51.0	4.28e-01	93.8%	84.1%
3bs3A00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.60	50.0	4.65e-01	91.7%	100.0%
3g7dA01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.58	46.0	3.86e-01	89.6%	98.8%

ECOD (100)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3944309	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.95	84.0	8.26e-01	93.8%	90.0%
4031535	101.1.1.275 ↗	alpha arrays › HTH › HTH › Three-helical HTH › GerE	0.94	87.0	8.02e-01	100.0%	80.0%
3974013	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.94	85.0	7.84e-01	100.0%	78.3%
3988145	101.1.6.0 ↗	alpha arrays › HTH › HTH › TrpR	0.94	76.0	7.54e-01	89.6%	82.0%
3968864	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.94	87.0	7.34e-01	100.0%	64.0%
4034200	101.1.1.275 ↗	alpha arrays › HTH › HTH › Three-helical HTH › GerE	0.93	85.0	7.61e-01	100.0%	73.8%
3977009	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.93	81.0	7.02e-01	93.8%	64.3%
4139052	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.93	85.0	7.21e-01	100.0%	64.0%
5028266	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.93	75.0	6.89e-01	85.4%	69.5%
4987653	101.1.2.139 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_23	0.93	75.0	7.71e-01	89.6%	91.1%
3640035	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.93	74.0	5.97e-01	89.6%	48.2%
4510105	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.93	71.0	7.68e-01	81.2%	97.5%
3945377	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.93	82.0	7.31e-01	95.8%	70.8%
4952294	101.1.2.870 ↗	alpha arrays › HTH › HTH › winged helix domain › GerE	0.92	75.0	7.11e-01	89.6%	74.5%
5043241	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.92	69.0	7.50e-01	79.2%	95.0%
3922450	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.92	71.0	7.66e-01	81.2%	97.5%
3942695	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.92	79.0	7.11e-01	93.8%	69.2%
3589359	101.1.1.68 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_38	0.92	67.0	7.31e-01	77.1%	92.5%
3090474	4020.1.1.0 ↗	a+b two layers › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes	0.92	79.0	5.55e-01	93.8%	32.6%
4927434	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.92	72.0	7.47e-01	87.5%	88.9%
4131887	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.92	85.0	7.02e-01	100.0%	60.8%
4960928	101.1.3.16 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › Sigma70_r4	0.92	79.0	7.31e-01	93.8%	75.0%
3943462	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.92	78.0	7.41e-01	91.7%	81.8%
3942478	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.92	79.0	7.58e-01	93.8%	81.8%
3967026	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.92	85.0	7.15e-01	100.0%	69.3%
4947436	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.92	79.0	7.57e-01	93.8%	83.6%
4008322	101.1.1.17 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_7	0.92	73.0	6.96e-01	85.4%	74.5%
4990647	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.91	72.0	6.84e-01	83.3%	72.7%
4008147	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.91	81.0	7.20e-01	95.8%	70.8%
3959252	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.91	83.0	7.67e-01	100.0%	81.7%
4054648	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.91	73.0	6.94e-01	89.6%	74.5%
4174590	101.1.2.61 ↗	alpha arrays › HTH › HTH › winged helix domain › Sigma70_r4	0.91	78.0	6.97e-01	91.7%	72.3%
3477795	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.91	74.0	7.66e-01	87.5%	93.3%
3962903	101.1.2.486 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_58	0.91	68.0	7.30e-01	79.2%	95.0%
4661582	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.91	80.0	5.96e-01	95.8%	43.6%
3590732	101.1.1.364 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_49	0.90	74.0	7.66e-01	87.5%	93.3%
4551350	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.90	83.0	6.46e-01	100.0%	53.7%
5024511	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.90	70.0	6.98e-01	83.3%	80.0%
3283074	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.90	82.0	6.66e-01	100.0%	56.5%
3972272	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.90	79.0	6.72e-01	95.8%	62.7%
3947091	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.90	77.0	7.15e-01	93.8%	75.0%
3991300	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.90	72.0	5.94e-01	89.6%	51.2%
4030763	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.90	78.0	7.03e-01	95.8%	70.8%
5056682	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.90	74.0	6.46e-01	89.6%	61.4%
3286659	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.90	81.0	7.10e-01	100.0%	68.6%
3979166	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.90	81.0	7.08e-01	100.0%	70.0%
3590541	142.1.1.3 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2	0.90	82.0	5.38e-01	100.0%	28.3%
4997092	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.90	74.0	6.46e-01	89.6%	61.4%
3962552	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.89	81.0	6.89e-01	100.0%	64.0%
3946608	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.89	81.0	7.07e-01	100.0%	77.1%
3976103	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.89	78.0	7.06e-01	97.9%	72.3%
4986612	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.89	67.0	6.97e-01	85.4%	86.7%
3980681	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.89	80.0	6.65e-01	100.0%	60.0%
3968151	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.89	80.0	6.55e-01	100.0%	61.2%
5064701	101.1.2.879 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF134	0.89	75.0	6.29e-01	93.8%	57.5%
4929382	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.89	73.0	6.94e-01	89.6%	78.2%
4031756	101.1.2.645 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_40	0.88	77.0	6.28e-01	95.8%	54.1%
4993585	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.88	67.0	6.18e-01	81.2%	65.0%
3879118	101.1.1.60 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_23	0.88	72.0	6.92e-01	89.6%	78.2%
4952807	101.1.1.60 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_23	0.88	71.0	6.03e-01	87.5%	56.0%
4007717	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.88	80.0	6.63e-01	100.0%	62.5%
4946254	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.88	71.0	7.35e-01	87.5%	93.3%
4952035	101.1.1.17 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_7	0.88	66.0	6.14e-01	83.3%	65.0%
4979402	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.87	71.0	6.61e-01	89.6%	71.7%
4159688	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.87	79.0	6.89e-01	100.0%	72.9%
4937081	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.87	78.0	7.04e-01	100.0%	73.8%
4541333	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.87	71.0	7.06e-01	89.6%	88.0%
5043001	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.87	75.0	5.74e-01	95.8%	46.7%
3544647	101.1.1.24 ↗	alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N	0.87	71.0	6.41e-01	89.6%	66.2%
4458444	101.1.1.42 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2	0.87	78.0	6.15e-01	100.0%	52.6%
4031116	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.86	68.0	6.30e-01	85.4%	68.3%
1159643	101.1.1.17 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_7	0.86	67.0	5.79e-01	83.3%	67.6%
5064314	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.86	69.0	6.40e-01	87.5%	70.0%
5006645	101.1.1.63 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_28	0.86	71.0	6.54e-01	89.6%	73.3%
4943227	101.1.1.63 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_28	0.86	69.0	7.07e-01	87.5%	93.3%
3565285	101.1.1.24 ↗	alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N	0.86	71.0	6.36e-01	89.6%	66.2%
4992594	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.86	66.0	6.78e-01	83.3%	88.9%
3753093	101.1.1.24 ↗	alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N	0.85	71.0	6.33e-01	89.6%	66.2%
3981688	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.85	72.0	6.54e-01	95.8%	70.8%
3789627	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.84	69.0	6.21e-01	89.6%	66.2%
3944389	101.1.3.4 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30	0.83	74.0	6.08e-01	100.0%	63.5%
3286340	101.1.3.4 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30	0.83	73.0	5.88e-01	100.0%	60.2%
4560931	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.83	71.0	6.18e-01	100.0%	62.7%
4002185	101.1.1.24 ↗	alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N	0.83	68.0	5.80e-01	89.6%	57.3%
2761	101.1.3.1 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE	0.82	72.0	5.95e-01	100.0%	57.5%
3946793	101.1.1.259 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Terminase_5	0.82	66.0	4.90e-01	87.5%	36.5%
4466704	101.1.3.4 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30	0.81	71.0	5.63e-01	100.0%	56.0%
3954318	101.1.1.300 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_30	0.81	71.0	5.79e-01	100.0%	56.7%
3286796	101.1.3.4 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30	0.81	70.0	5.66e-01	100.0%	57.9%
3404418	101.1.1.24 ↗	alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N	0.81	65.0	5.74e-01	89.6%	62.9%
3282047	101.1.3.4 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30	0.80	71.0	5.56e-01	100.0%	59.0%
3958970	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.80	69.0	5.91e-01	100.0%	63.7%
3955106	101.1.3.4 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30	0.80	70.0	5.69e-01	100.0%	60.0%
4927516	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.79	66.0	6.17e-01	93.8%	78.3%
4964802	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.79	66.0	6.14e-01	93.8%	90.0%
5030780	101.1.3.0 ↗	alpha arrays › HTH › HTH › tetra-helical, LuxR-like	0.78	60.0	6.02e-01	89.6%	88.0%
3983783	101.1.1.13 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_1	0.75	60.0	4.86e-01	91.7%	52.6%
5071227	2005.1.1.18 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › NAD_synthase	0.74	67.0	4.05e-01	100.0%	37.0%
3693312	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.74	58.0	5.52e-01	91.7%	75.0%
3410877	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.72	56.0	5.06e-01	89.6%	62.9%

D4 high residues 430-493

PDB

D5 medium residues 11-80

PDB

Domain cluster: representative

CATH (56)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1zpyA00	6.10.140.1960	Special › Helix non-globular › Helix Hairpins ›	0.79	58.0	5.27e-01	77.1%	67.0%
1wpaA01	6.10.140.340	Special › Helix non-globular › Helix Hairpins ›	0.78	57.0	5.07e-01	77.1%	96.0%
1ma1A01	1.10.287.990	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain	0.78	57.0	5.93e-01	77.1%	89.1%
3bt5A00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.77	58.0	4.50e-01	81.4%	41.7%
4e40A00	1.20.1260.80	Mainly Alpha › Up-down Bundle › Ferritin ›	0.75	56.0	3.82e-01	80.0%	62.0%
4e4eA01	1.10.287.990	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain	0.75	56.0	5.65e-01	80.0%	84.5%
3am6A00	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.75	56.0	3.90e-01	80.0%	30.8%
4e6nA02	6.10.140.1010	Special › Helix non-globular › Helix Hairpins ›	0.75	56.0	5.74e-01	80.0%	93.9%
3cazB00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.74	55.0	3.89e-01	78.6%	52.9%
6yz2A01	1.20.120.350	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C	0.74	57.0	4.81e-01	84.3%	64.2%
3fcnA00	1.20.1220.20	Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Uncharcterised protein PF01724	0.74	59.0	4.53e-01	87.1%	60.8%
2lw1A00	1.10.287.380	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain	0.74	58.0	5.46e-01	85.7%	85.9%
3d36B02	1.10.287.130	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain	0.73	53.0	5.64e-01	75.7%	86.9%
5b1aC01	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.72	52.0	5.33e-01	78.6%	77.9%
1vf7A03	1.10.287.470	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.72	53.0	5.61e-01	78.6%	98.3%
4l8jA04	1.10.287.470	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.72	53.0	5.66e-01	77.1%	94.9%
2e9xA01	1.20.58.1030	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.72	54.0	4.44e-01	81.4%	53.1%
4qhpA05	1.25.50.10	Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain	0.72	51.0	3.26e-01	75.7%	15.9%
4dkcB00	1.20.1250.80	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-34	0.72	51.0	3.94e-01	75.7%	33.1%
2ic6A00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.71	51.0	5.13e-01	77.1%	90.1%
3rc3A05	1.20.58.1080	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.71	51.0	4.35e-01	81.4%	46.9%
3uo2B02	1.20.1280.20	Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain	0.71	52.0	4.91e-01	78.6%	67.9%
1ydxA02	1.10.287.1120	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein	0.71	53.0	4.88e-01	80.0%	70.0%
5ux1D00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.70	54.0	3.91e-01	82.9%	54.8%
1uurA01	1.20.58.240	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1	0.70	52.0	4.54e-01	81.4%	66.4%
1sj8A02	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.70	52.0	4.29e-01	78.6%	59.0%
4iggA01	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.70	52.0	5.33e-01	81.4%	86.6%
1kfdA02	1.20.1060.10	Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4	0.69	52.0	5.24e-01	81.4%	80.3%
5z7qA00	1.20.1330.10	Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain	0.69	51.0	3.85e-01	80.0%	73.3%
7cj3A01	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.68	56.0	3.86e-01	92.9%	29.1%
3pwxA01	1.20.1330.10	Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain	0.68	51.0	3.78e-01	80.0%	36.4%
6xkyA01	1.20.1330.10	Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain	0.68	51.0	3.74e-01	80.0%	47.6%
2rp4A00	6.10.280.60	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain	0.68	47.0	4.69e-01	75.7%	70.4%
1ni3A03	1.10.150.300	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain	0.67	49.0	4.57e-01	80.0%	62.6%
2hh7A00	1.20.58.1000	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer	0.67	48.0	4.52e-01	75.7%	71.8%
3uumA00	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.66	49.0	4.09e-01	78.6%	47.5%
8d7hD01	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.65	47.0	3.60e-01	77.1%	35.3%
1o5hA00	1.20.120.680	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle	0.65	52.0	3.76e-01	87.1%	38.5%
1xwjA01	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.65	55.0	4.51e-01	94.3%	90.0%
1t7sA00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.65	51.0	4.21e-01	85.7%	55.0%
2xzmO02	1.10.287.10	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding	0.64	46.0	4.60e-01	74.3%	77.1%
2zueA03	1.10.730.10	Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1	0.64	48.0	4.05e-01	78.6%	46.2%
3anwA01	1.20.58.1030	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.64	48.0	4.15e-01	81.4%	52.2%
4p9tA01	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.63	52.0	4.46e-01	94.3%	91.7%
2dnxA00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.63	47.0	3.93e-01	81.4%	58.5%
2bdeA03	1.20.58.1160	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.62	47.0	4.57e-01	80.0%	92.2%
1wa8A00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.62	48.0	4.28e-01	82.9%	72.7%
4w4kA00	1.10.287.850	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain	0.62	47.0	4.52e-01	81.4%	74.4%
4mh6A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.61	45.0	3.54e-01	78.6%	35.8%
8d3mA02	1.20.120.920	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain	0.61	44.0	3.09e-01	78.6%	55.0%
3pe0A01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.60	44.0	3.95e-01	80.0%	54.5%
2y39A00	1.20.120.1490	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.59	48.0	4.24e-01	92.9%	72.7%
1xfiA02	1.20.1700.10	Mainly Alpha › Up-down Bundle › AF1104-like › AF1104-like	0.57	42.0	3.91e-01	81.4%	62.2%
3l1nA02	1.20.1280.140	Mainly Alpha › Up-down Bundle › Monooxygenase ›	0.57	42.0	3.90e-01	78.6%	74.7%
1yq1A02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.56	40.0	3.58e-01	80.0%	61.6%
1rw9A01	1.50.10.100	Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase	0.54	45.0	2.88e-01	94.3%	23.0%

ECOD (61)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3680096	174.1.1.0 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain	0.80	59.0	4.67e-01	77.1%	52.6%
4857875	5001.1.1.1 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1	0.79	58.0	5.43e-01	77.1%	72.6%
3377936	3922.1.1.173 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF3493	0.78	59.0	5.52e-01	80.0%	71.8%
3787587	604.6.1.1 ↗	alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT	0.78	61.0	5.41e-01	84.3%	64.0%
3425693	174.1.1.1 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin	0.78	56.0	5.20e-01	77.1%	66.7%
3844040	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.76	57.0	5.93e-01	80.0%	84.6%
3250375	192.1.1.0 ↗	alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain	0.76	56.0	5.49e-01	78.6%	72.0%
4927596	604.5.1.0 ↗	alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895)	0.76	58.0	4.70e-01	81.4%	46.9%
5012651	150.1.1.3 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin	0.76	53.0	5.03e-01	74.3%	69.4%
4964664	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.76	57.0	5.88e-01	80.0%	86.2%
4961492	5055.1.1.0 ↗	extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel	0.76	56.0	5.11e-01	80.0%	63.2%
3531576	192.13.1.0 ↗	alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like	0.75	53.0	5.40e-01	81.4%	75.7%
5038847	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.74	56.0	5.63e-01	80.0%	82.9%
5062243	601.4.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains	0.74	53.0	4.70e-01	75.7%	56.0%
4463756	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.74	56.0	5.68e-01	81.4%	81.4%
3596042	4163.1.1.0 ↗	alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like	0.73	55.0	4.47e-01	81.4%	52.6%
5030936	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.73	55.0	4.01e-01	81.4%	32.8%
3815712	5086.1.1.15 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Mit_KHE1	0.73	59.0	4.08e-01	90.0%	33.8%
3247744	192.4.1.12 ↗	alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › FmiP_Thoc5	0.72	55.0	4.77e-01	81.4%	55.2%
3945517	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.71	53.0	4.80e-01	80.0%	60.0%
3231463	632.8.1.2 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C	0.71	52.0	4.75e-01	78.6%	63.2%
3564754	604.1.1.96 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Bap31	0.71	56.0	4.52e-01	85.7%	72.6%
4329615	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.71	50.0	5.07e-01	74.3%	98.6%
2627929	5068.1.1.1 ↗	alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Cytochrom_B_C	0.70	56.0	4.78e-01	87.1%	55.7%
3592927	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.70	62.0	4.83e-01	100.0%	74.2%
5028289	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.70	51.0	3.34e-01	80.0%	17.7%
4988222	4044.1.1.0 ↗	alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins	0.70	51.0	4.93e-01	78.6%	71.2%
3619957	5055.1.1.0 ↗	extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel	0.70	50.0	4.77e-01	82.9%	63.5%
5072280	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.70	51.0	3.68e-01	80.0%	33.5%
3973900	192.8.1.331 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF4824	0.70	51.0	4.79e-01	77.1%	62.4%
3618523	604.6.1.0 ↗	alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain	0.69	53.0	4.91e-01	82.9%	67.8%
3582885	192.4.1.12 ↗	alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › FmiP_Thoc5	0.69	54.0	4.56e-01	84.3%	53.9%
3264612	5050.1.1.0 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter	0.68	62.0	4.50e-01	100.0%	65.0%
4606152	4163.1.1.1 ↗	alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5	0.68	52.0	3.97e-01	84.3%	53.5%
3611163	2004.1.1.480 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29	0.68	50.0	3.06e-01	80.0%	12.8%
3991480	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.67	50.0	3.94e-01	78.6%	41.4%
3797118	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.67	50.0	4.19e-01	78.6%	56.5%
3921752	5050.1.1.1 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr	0.66	61.0	4.11e-01	100.0%	61.3%
4927007	605.1.1.2 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › H-kinase_dim	0.66	47.0	5.23e-01	78.6%	96.4%
4945528	140.1.1.11 ↗	alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1	0.66	49.0	3.58e-01	78.6%	73.3%
54352	133.2.1.0 ↗	alpha bundles › DH domain-like › Methenyltetrahydrofolate cyclohydrolase-like › Methenyltetrahydrofolate cyclohydrolase-like	0.65	52.0	3.78e-01	87.1%	38.9%
3681	133.2.1.1 ↗	alpha bundles › DH domain-like › Methenyltetrahydrofolate cyclohydrolase-like › Methenyltetrahydrofolate cyclohydrolase-like › FTCD_C	0.65	52.0	3.76e-01	87.1%	38.5%
3718408	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.65	54.0	4.62e-01	90.0%	68.2%
4013484	4121.1.1.0 ↗	a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like	0.65	48.0	3.50e-01	81.4%	43.9%
3517598	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.65	47.0	4.83e-01	75.7%	87.7%
3474564	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.65	50.0	4.41e-01	84.3%	58.1%
3459313	616.1.1.1 ↗	alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Ribosomal_S15	0.65	46.0	4.23e-01	74.3%	65.6%
3720723	5059.1.1.8 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA	0.64	48.0	3.59e-01	81.4%	33.9%
3587056	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.62	47.0	3.65e-01	81.4%	35.6%
1095885	6128.1.1.0 ↗		0.62	46.0	4.78e-01	78.6%	98.4%
3423908	6155.1.1.0 ↗	alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter	0.62	47.0	4.32e-01	84.3%	70.5%
5072084	140.1.1.7 ↗	alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2	0.61	48.0	3.70e-01	85.7%	41.2%
3304770	4163.1.1.1 ↗	alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5	0.60	44.0	3.55e-01	84.3%	52.5%
3234298	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.59	40.0	4.33e-01	75.7%	92.7%
5081330	4163.1.1.0 ↗	alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like	0.58	43.0	3.63e-01	84.3%	44.4%
5069340	4163.1.1.1 ↗	alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5	0.58	43.0	3.76e-01	84.3%	70.8%
3518263	4207.1.2.1 ↗	alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › Med7	0.57	43.0	3.76e-01	84.3%	61.7%
4652999	192.11.1.2 ↗	alpha bundles › Long alpha-hairpin › C-terminal UvrC-binding domain of UvrB › C-terminal UvrC-binding domain of UvrB › CysS_C	0.56	45.0	3.59e-01	92.9%	52.6%
4048104	109.4.1.1151 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HIR3_helical	0.56	47.0	2.77e-01	98.6%	76.4%
3726467	4033.1.1.1 ↗	alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N	0.53	39.0	3.32e-01	80.0%	88.3%
None	—		0.51	42.0	2.92e-01	95.7%	77.4%

D6 medium residues 81-152

PDB

Domain cluster: rep: NC_024788.1__YP_009055966.1__LD11_gp201__00201__D4-94

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF04542.21 best	Sigma70_r2	31.4	1.80e-07	95.8%	78.9%