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MW824421.1__QZI92902.1__SIPHO067v1_p0062__00062

Bact-Vir

MW824421.1__QZI92902.1__SIPHO067v1_p0062__00062

Identity

Accession:
MW824421 ↗
Kingdom:
phage

Quality

91.4 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Vibrio_phage_51E28.1

TaxID: 2859334

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 362-604
PDB
Domain cluster: rep: MZ501264.1__QZA70128.1__274BB002_59__00058__D5-186
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6vddD01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.89 66.0 7.60e-01 97.1% 100.0%
1d8yA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.88 76.0 8.09e-01 97.1% 99.1%
1yt3A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.87 68.0 7.61e-01 97.5% 100.0%
4nlcA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.85 69.0 6.69e-01 99.6% 77.1%
1bdp001 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.84 65.0 7.27e-01 97.1% 99.0%
3cymA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.84 67.0 7.27e-01 98.4% 96.6%
3safB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.83 69.0 6.52e-01 99.6% 73.6%
2e6mA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.83 61.0 6.90e-01 88.1% 96.2%
7r0kB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.82 78.0 7.71e-01 97.9% 100.0%
7pbkA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 72.0 7.53e-01 100.0% 100.0%
7sxqA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.79 72.0 7.17e-01 98.8% 92.3%
2gv9A03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.77 56.0 5.94e-01 74.9% 100.0%
7jw2A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.76 64.0 6.87e-01 93.0% 100.0%
3iayA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.74 55.0 5.92e-01 75.7% 100.0%
4qclA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.73 60.0 5.76e-01 84.0% 90.4%
1x9mA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.73 61.0 6.40e-01 86.8% 100.0%
1d5aA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.73 59.0 6.26e-01 83.5% 98.6%
2d5rA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.70 64.0 6.32e-01 95.1% 100.0%
7t2sA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.69 49.0 5.76e-01 78.2% 100.0%
1uocB00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.68 63.0 6.25e-01 96.3% 96.1%
2py5A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.68 50.0 5.78e-01 81.1% 100.0%
1j9aA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.64 47.0 5.40e-01 81.5% 100.0%
3nutB02 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.56 26.0 3.55e-01 86.4% 82.8%
4egvA02 2.40.50.840 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.52 18.0 3.03e-01 78.6% 92.0%
2dq4A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 24.0 3.11e-01 77.8% 77.6%
ECOD (85)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3388110 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.90 76.0 6.69e-01 97.5% 63.3%
4037090 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.89 76.0 8.05e-01 98.4% 96.8%
3163747 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.88 78.0 5.92e-01 99.2% 44.7%
4541130 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.88 68.0 7.66e-01 97.5% 100.0%
4233346 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.88 74.0 6.54e-01 96.7% 63.6%
4165451 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 76.0 7.66e-01 99.2% 89.0%
4677993 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 76.0 8.01e-01 97.5% 98.6%
2469642 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 70.0 7.54e-01 99.6% 95.7%
3980678 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.87 72.0 6.30e-01 92.6% 61.2%
4882445 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 69.0 7.58e-01 98.4% 97.1%
4367091 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 65.0 5.92e-01 96.3% 62.3%
4339694 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 67.0 5.25e-01 99.2% 42.6%
3993770 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.84 69.0 6.50e-01 98.8% 72.5%
4995738 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 73.0 7.72e-01 98.8% 99.1%
4031810 2484.1.1.96 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_polI_exo1 0.84 65.0 7.29e-01 97.1% 99.0%
3908305 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.83 63.0 6.83e-01 88.9% 90.7%
160349 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.82 61.0 6.79e-01 88.1% 93.8%
3434621 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.82 68.0 6.45e-01 99.2% 73.9%
3839957 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.82 66.0 5.85e-01 99.6% 59.7%
3283743 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.82 68.0 6.00e-01 99.2% 62.1%
2579558 2484.1.1.96 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_polI_exo1 0.81 64.0 6.99e-01 94.2% 96.5%
4603831 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 63.0 6.38e-01 89.3% 79.6%
3185973 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 69.0 6.46e-01 100.0% 74.6%
3965745 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 76.0 7.22e-01 100.0% 85.8%
1756776 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 69.0 6.39e-01 99.6% 72.9%
5066483 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.80 55.0 6.62e-01 78.2% 100.0%
3730951 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 69.0 6.71e-01 98.4% 82.3%
3665458 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 60.0 6.62e-01 90.5% 93.1%
4343577 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.79 46.0 4.68e-01 87.7% 57.1%
3261268 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.79 75.0 6.28e-01 98.8% 68.6%
3661219 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 61.0 6.39e-01 92.6% 86.7%
4291004 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.78 60.0 5.52e-01 98.8% 62.6%
3266621 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.77 52.0 6.21e-01 84.8% 98.8%
3600231 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.77 66.0 6.33e-01 88.1% 82.6%
3499910 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 71.0 6.53e-01 97.5% 100.0%
3569539 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.75 53.0 6.14e-01 86.8% 96.1%
3932596 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.75 60.0 6.09e-01 81.5% 100.0%
3922908 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.75 63.0 6.47e-01 92.2% 91.3%
None — 0.75 60.0 5.17e-01 83.1% 66.8%
3256261 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.74 60.0 5.96e-01 83.1% 93.3%
1822623 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.74 60.0 5.78e-01 83.5% 90.1%
None — 0.74 65.0 4.63e-01 90.5% 55.5%
5056578 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.74 60.0 5.58e-01 83.1% 84.1%
3797773 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.74 60.0 5.56e-01 83.1% 85.1%
5005285 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.74 60.0 6.12e-01 83.1% 98.7%
3558197 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.74 62.0 6.26e-01 86.8% 100.0%
3710418 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.74 62.0 5.23e-01 86.0% 94.4%
4874454 2.1.1.25 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 0.74 60.0 5.84e-01 83.5% 90.9%
3606428 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.74 58.0 5.96e-01 81.1% 100.0%
3825992 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.73 59.0 5.89e-01 82.7% 98.4%
4972474 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.73 61.0 4.28e-01 85.2% 36.7%
1790898 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.73 60.0 5.77e-01 84.0% 89.3%
3705562 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 59.0 4.21e-01 83.1% 36.9%
3988496 2484.1.1.13 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.73 55.0 5.86e-01 83.1% 86.5%
3684974 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 59.0 4.18e-01 82.7% 38.6%
3676005 4970.1.1.2 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.73 66.0 5.43e-01 97.5% 56.7%
3496492 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.73 59.0 5.51e-01 82.7% 86.2%
4997716 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.73 59.0 6.16e-01 83.1% 100.0%
3784398 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.73 59.0 5.79e-01 82.7% 98.8%
3168836 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.73 59.0 5.79e-01 82.7% 99.2%
3368695 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.73 64.0 5.31e-01 90.5% 92.1%
4988803 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.73 59.0 4.90e-01 83.1% 84.3%
3214818 304.114.1.0 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.73 59.0 4.98e-01 82.7% 62.9%
3206356 304.114.1.0 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.73 58.0 4.86e-01 82.7% 63.7%
3794217 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.73 60.0 4.51e-01 84.4% 53.6%
4023334 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.72 59.0 5.56e-01 82.7% 91.1%
5019480 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.72 60.0 4.15e-01 85.2% 34.6%
5063605 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.72 59.0 5.10e-01 83.5% 59.4%
4931271 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.72 57.0 6.17e-01 87.2% 94.3%
3607580 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.72 64.0 6.72e-01 97.9% 100.0%
4935884 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.72 58.0 4.78e-01 83.5% 58.8%
3628202 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.72 65.0 4.58e-01 93.8% 56.8%
3456683 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.72 58.0 6.24e-01 84.4% 96.7%
2958185 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.71 58.0 5.49e-01 83.5% 91.1%
3927943 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.71 64.0 6.40e-01 99.2% 92.8%
3192875 304.114.1.0 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.71 58.0 4.54e-01 84.8% 55.3%
3274142 2484.1.1.45 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 0.71 65.0 5.87e-01 96.3% 99.7%
3600515 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.70 66.0 6.47e-01 97.9% 100.0%
4323378 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.69 62.0 5.83e-01 94.2% 94.5%
None — 0.68 62.0 4.41e-01 93.8% 54.8%
3683241 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.68 62.0 5.53e-01 94.2% 85.9%
3466667 2484.1.1.161 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.67 61.0 4.33e-01 94.2% 59.8%
4805117 2484.1.1.161 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.65 44.0 4.64e-01 91.4% 74.5%
4259073 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.65 59.0 5.94e-01 97.1% 95.0%
3759576 2484.1.1.288 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PML_C 0.64 54.0 5.36e-01 88.1% 94.9%
D2 high residues 753-855
PDB
Domain cluster: representative
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ieeA02 1.20.58.820 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 0.61 42.0 4.24e-01 70.9% 98.1%
2kbbA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.60 42.0 3.56e-01 72.8% 56.9%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.56 37.0 4.10e-01 70.9% 83.1%
3hdeC00 1.10.530.40 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.55 38.0 3.29e-01 70.9% 94.5%
4al0A00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.55 37.0 3.30e-01 86.4% 47.9%
2ba0A03 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.54 35.0 3.81e-01 84.5% 80.7%
2oznB01 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.54 36.0 4.01e-01 88.3% 87.5%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.53 38.0 3.35e-01 75.7% 89.8%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 38.0 3.57e-01 74.8% 78.9%
3t9oB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.52 38.0 3.69e-01 78.6% 90.0%
4n4gA01 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.52 42.0 4.12e-01 89.3% 94.6%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.52 36.0 3.20e-01 70.9% 62.7%
6dcjA02 1.25.40.650 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 36.0 3.69e-01 88.3% 75.0%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3589765 601.41.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › C-terminal domain in uncharacterized DUF3829-like protein › C-terminal domain in uncharacterized DUF3829-like protein 0.60 42.0 4.47e-01 72.8% 100.0%
5050736 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.58 48.0 4.02e-01 92.2% 95.7%
3989675 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.55 40.0 3.83e-01 75.7% 75.0%
4010901 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.55 40.0 3.85e-01 76.7% 87.5%
3546062 376.1.2.39 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain › RHG29_45_N 0.55 38.0 3.80e-01 71.8% 80.9%
4997052 601.14.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.55 37.0 4.08e-01 89.3% 85.9%
3683769 206.1.1.70 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.54 42.0 2.75e-01 82.5% 23.8%
3702537 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.53 41.0 2.99e-01 82.5% 92.1%
4032962 601.18.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.52 37.0 3.62e-01 74.8% 73.9%
3283105 191.1.1.48 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_46 0.51 41.0 3.78e-01 87.4% 80.0%
4935178 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 37.0 3.01e-01 76.7% 87.8%
4681325 632.19.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A 0.50 33.0 3.68e-01 86.4% 86.3%
D3 medium residues 17-198_312-361
PDB
Domain cluster: rep: NC_070967.1__YP_010671382.1__PQC17_gp233__00233__D3-158_252-294
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02739.23 best 5_3_exonuc_N 49.4 6.00e-13 66.0% 61.6%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3zdbA01 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.84 55.0 6.72e-01 78.4% 97.5%
1xo1A02 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.80 53.0 6.46e-01 89.2% 98.1%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3942272 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.83 60.0 7.02e-01 76.3% 99.4%
4995752 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.83 58.0 6.88e-01 75.0% 98.8%
3969358 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.82 56.0 6.79e-01 75.9% 100.0%
4031817 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.82 58.0 6.86e-01 78.4% 98.2%
3838776 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.81 56.0 6.65e-01 78.4% 97.6%
3261281 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.81 56.0 6.65e-01 78.4% 97.6%
4031881 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.81 58.0 6.72e-01 76.3% 96.6%
4324598 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.80 59.0 6.69e-01 90.5% 94.1%
4355422 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.80 58.0 6.67e-01 89.7% 97.1%
4125023 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.80 57.0 6.64e-01 78.4% 98.2%
3964138 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.80 59.0 6.70e-01 88.4% 96.7%
4238071 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.80 59.0 6.82e-01 78.4% 99.4%
4157264 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.80 59.0 6.67e-01 76.3% 96.1%
4322588 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.79 59.0 6.70e-01 87.9% 98.3%
4165496 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.78 60.0 6.74e-01 90.5% 98.9%
3831671 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.77 59.0 6.51e-01 78.4% 98.5%
3942445 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.77 59.0 6.63e-01 99.6% 98.4%
3283240 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.77 59.0 6.47e-01 78.4% 93.3%
4299585 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.76 59.0 6.62e-01 100.0% 98.9%
3329169 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.74 52.0 6.00e-01 78.4% 94.3%
4136793 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.74 62.0 6.57e-01 99.1% 96.2%
3293941 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.73 61.0 6.49e-01 88.4% 95.2%
3710018 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.70 60.0 6.27e-01 88.8% 96.7%
3687797 323.1.1.0 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.51 32.0 3.55e-01 91.4% 77.8%
D4 medium residues 199-311
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3zdbA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.79 50.0 5.60e-01 83.2% 80.9%
5hmlA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.75 50.0 5.79e-01 99.1% 97.5%
6yttA01 1.10.8.190 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Carbon monoxide dehydrogenase alpha subunit. Chain M, domain 1 0.58 34.0 3.58e-01 75.2% 64.0%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.58 34.0 3.87e-01 77.9% 78.3%
1v4aA01 1.10.4050.10 Mainly Alpha › Orthogonal Bundle › Nucleotidyltransferase substrate binding subunit/domain fold › Glutamine synthase adenylyltransferase GlnE 0.57 44.0 4.53e-01 98.2% 87.2%
2c0gA02 1.20.1150.12 Mainly Alpha › Up-down Bundle › Endoplasmic reticulum protein erp29 › Endoplasmic reticulum resident protein 29, C-terminal domain 0.54 35.0 3.66e-01 72.6% 69.8%
2o8hA00 1.10.1300.10 Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 0.50 41.0 3.10e-01 92.0% 67.4%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
None — 0.83 55.0 6.12e-01 98.2% 84.4%
4030601 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.80 52.0 5.20e-01 98.2% 64.3%
2168201 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.79 52.0 5.03e-01 83.2% 60.3%
4561919 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.78 51.0 3.88e-01 84.1% 30.2%
3956065 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.78 52.0 6.11e-01 84.1% 96.2%
4364220 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.78 52.0 5.11e-01 84.1% 63.3%
4575153 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.78 50.0 5.18e-01 84.1% 69.5%
4481584 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.77 51.0 5.07e-01 83.2% 65.2%
4030950 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.77 48.0 4.85e-01 83.2% 62.6%
4995753 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.75 50.0 4.91e-01 95.6% 63.9%
3964109 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.74 47.0 5.66e-01 84.1% 97.3%
4299586 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.74 49.0 5.79e-01 81.4% 96.2%
3942250 102.1.1.4 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.69 54.0 5.10e-01 97.3% 69.6%
3283743 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.61 40.0 2.87e-01 82.3% 22.1%
2410023 141.1.1.8 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_syn_C_2 0.52 45.0 3.39e-01 99.1% 59.0%
D5 medium residues 607-640_860-973
PDB
Domain cluster: rep: term1_stool_scaffold_19_prodigal-single.1__X__X__00096__D449-569
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6vddA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.89 64.0 7.24e-01 92.6% 94.8%
1bdp002 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.84 58.0 6.65e-01 92.6% 94.5%
7r0kA01 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.81 58.0 6.73e-01 79.1% 100.0%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 40.0 3.34e-01 89.2% 32.6%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.75 34.0 3.83e-01 84.5% 54.2%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 37.0 4.37e-01 89.9% 69.9%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.70 37.0 4.26e-01 87.2% 68.2%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.70 33.0 3.72e-01 84.5% 57.5%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.69 32.0 3.57e-01 82.4% 53.8%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 38.0 4.24e-01 87.2% 67.8%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.68 32.0 3.78e-01 86.5% 62.3%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 35.0 3.85e-01 91.9% 61.5%
2oexA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.66 39.0 3.55e-01 89.2% 43.7%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.66 34.0 3.90e-01 84.5% 65.8%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.63 40.0 5.04e-01 87.2% 100.0%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.62 37.0 3.57e-01 89.2% 52.4%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 30.0 3.32e-01 93.2% 54.2%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.62 32.0 3.66e-01 85.8% 67.3%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.61 36.0 3.93e-01 89.2% 68.8%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.61 36.0 4.29e-01 89.2% 85.3%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.58 34.0 3.50e-01 91.2% 58.5%
2nnwA02 1.10.287.4070 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 45.0 4.90e-01 89.2% 96.1%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 35.0 3.85e-01 85.1% 74.6%
5dn6G02 3.40.1380.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › ATP synthase, F1 complex, gamma subunit 0.56 45.0 4.12e-01 84.5% 100.0%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 28.0 2.88e-01 82.4% 46.5%
3aonA00 1.10.287.3240 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 46.0 4.22e-01 89.2% 71.8%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 42.0 3.99e-01 85.8% 70.5%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.52 41.0 4.14e-01 89.2% 81.5%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.52 39.0 4.44e-01 85.8% 100.0%
1jb0A00 1.20.1130.10 Mainly Alpha › Up-down Bundle › Photosystem I p700 chlorophyll A apoprotein A1 › Photosystem I PsaA/PsaB 0.52 45.0 2.83e-01 91.9% 18.6%
1bgcA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 41.0 4.02e-01 83.8% 98.1%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4339694 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.88 69.0 4.70e-01 100.0% 25.8%
4622747 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.84 63.0 4.65e-01 100.0% 33.0%
4975019 4970.1.1.0 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.82 66.0 6.67e-01 100.0% 84.1%
3221571 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.79 33.0 3.60e-01 87.8% 46.4%
3810801 632.22.1.139 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › KIF21A_4th 0.79 38.0 3.84e-01 89.2% 46.7%
3932694 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.78 35.0 4.32e-01 87.2% 65.0%
4024559 4970.1.1.2 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.74 64.0 5.99e-01 100.0% 75.3%
3849769 3755.3.1.295 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › WWC1 0.74 39.0 4.14e-01 89.2% 57.0%
3858356 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.73 42.0 4.27e-01 89.2% 58.6%
3781013 3291.1.1.170 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › WWC1 0.72 39.0 4.08e-01 88.5% 57.8%
3809724 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 38.0 3.91e-01 85.8% 55.7%
3999485 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 36.0 3.65e-01 89.2% 51.4%
4025229 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.66 40.0 4.25e-01 89.2% 68.5%
4027257 3871.1.1.1 ↗ alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.66 34.0 3.44e-01 74.3% 49.7%
4086322 5086.1.1.205 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PF30209 0.65 38.0 3.65e-01 89.2% 50.9%
3609510 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.65 43.0 3.90e-01 89.2% 53.5%
3728953 3926.1.1.2 ↗ alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D › Vma22_CCDC115 0.64 48.0 4.91e-01 89.2% 80.7%
3566283 4970.1.1.17 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › CpG_bind_C 0.64 51.0 5.24e-01 89.9% 85.5%
3782160 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.64 37.0 2.89e-01 89.9% 27.9%
3605635 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.62 42.0 4.60e-01 89.2% 82.4%
3605252 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 40.0 3.91e-01 89.2% 60.0%
3708137 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 33.0 3.26e-01 89.9% 49.4%
4945184 606.1.1.1 ↗ alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.59 46.0 5.04e-01 89.2% 97.6%
3299690 1075.5.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.58 32.0 3.01e-01 75.0% 44.0%
4933289 606.1.1.1 ↗ alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.58 46.0 4.88e-01 89.2% 93.1%
4982712 606.1.1.1 ↗ alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.56 45.0 4.72e-01 89.2% 91.9%
3870735 601.25.1.5 ↗ alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › OPA1_C 0.56 44.0 4.80e-01 83.8% 98.4%
4446434 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 41.0 4.29e-01 89.2% 80.7%
3859550 192.2.1.1 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.55 38.0 4.16e-01 89.2% 86.7%
3532021 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 34.0 3.62e-01 89.2% 70.8%
4976497 4163.1.1.0 ↗ alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.54 34.0 3.72e-01 88.5% 75.8%
3305910 604.3.1.37 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF2921 0.54 29.0 3.23e-01 89.2% 63.5%
3657813 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.54 45.0 4.44e-01 89.2% 99.4%
3598174 192.5.1.0 ↗ alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.54 43.0 4.69e-01 89.2% 98.4%
3768459 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.53 45.0 4.15e-01 89.2% 96.2%
3485424 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.52 42.0 4.60e-01 83.1% 100.0%
4116038 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.52 39.0 3.84e-01 89.2% 72.9%
3965537 5067.1.1.2 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF 0.50 42.0 3.59e-01 87.8% 91.7%
3611420 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.50 41.0 4.38e-01 87.2% 95.4%
D6 medium residues 641-752
PDB
Domain cluster: representative
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6pmiF01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.72 35.0 4.10e-01 93.8% 65.0%
3rlbA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.68 41.0 3.50e-01 97.3% 37.5%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.68 33.0 3.80e-01 90.2% 61.2%
3cxbA03 1.10.1740.30 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain 0.67 30.0 3.51e-01 95.5% 59.3%
3bvxA02 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.64 45.0 4.54e-01 72.3% 80.2%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 46.0 4.70e-01 74.1% 86.0%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 45.0 4.20e-01 74.1% 64.3%
1r6bX03 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.63 30.0 3.40e-01 95.5% 56.8%
4a25B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 44.0 3.91e-01 72.3% 88.8%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.63 38.0 4.62e-01 70.5% 100.0%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.62 47.0 4.50e-01 78.6% 77.3%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.61 33.0 3.80e-01 92.0% 70.6%
6ldiF01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 33.0 3.57e-01 92.0% 60.4%
3o7qA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.59 41.0 3.44e-01 71.4% 74.0%
4c3eM00 1.20.120.1350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain 0.58 42.0 3.84e-01 75.9% 62.6%
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.58 30.0 3.06e-01 94.6% 47.8%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 41.0 3.91e-01 76.8% 72.5%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.56 50.0 4.16e-01 97.3% 86.2%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 35.0 3.15e-01 99.1% 44.4%
3jz0A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.56 41.0 3.99e-01 78.6% 75.4%
2oauA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 32.0 3.41e-01 92.9% 61.8%
1cpqA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.56 42.0 4.01e-01 79.5% 82.2%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.55 39.0 4.00e-01 72.3% 80.6%
1at9A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 44.0 3.54e-01 87.5% 79.6%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 34.0 2.63e-01 97.3% 28.7%
1vhnA02 1.10.1200.80 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Putative flavin oxidoreducatase; domain 2 0.55 34.0 4.07e-01 78.6% 98.6%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 32.0 3.51e-01 91.1% 71.0%
2gmyD00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.54 45.0 4.15e-01 92.0% 95.2%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 36.0 2.72e-01 97.3% 29.8%
1tfkB00 1.20.120.650 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Colicin D 0.53 37.0 4.07e-01 70.5% 94.2%
6a95A01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.53 40.0 3.94e-01 82.1% 81.7%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.53 46.0 3.88e-01 95.5% 84.3%
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 30.0 3.50e-01 88.4% 76.2%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 37.0 3.83e-01 72.3% 94.2%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 36.0 3.54e-01 72.3% 94.3%
4bejB02 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.51 46.0 3.66e-01 99.1% 71.7%
3bq9A02 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 40.0 3.00e-01 88.4% 98.8%
2pusA02 1.10.287.540 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.51 26.0 3.42e-01 94.6% 98.1%
2igpA00 1.10.418.30 Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Ncd80 complex, Ncd80 subunit 0.51 39.0 3.97e-01 83.0% 89.5%
1mzgB00 3.90.1010.10 Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › 0.50 36.0 3.37e-01 75.0% 88.1%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4359328 142.1.1.44 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › GerPC 0.78 40.0 4.25e-01 96.4% 56.0%
3266960 611.8.1.1 ↗ alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › Ariadne 0.65 45.0 3.96e-01 71.4% 55.2%
3997336 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.64 47.0 4.56e-01 75.9% 85.6%
3290415 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.64 41.0 3.10e-01 94.6% 29.2%
3573589 632.22.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.63 43.0 4.54e-01 70.5% 98.0%
3360205 632.1.1.3 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid 0.62 44.0 4.76e-01 73.2% 91.6%
3436259 632.15.1.5 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › Rx_N 0.62 43.0 4.28e-01 72.3% 78.3%
3232199 4177.1.1.10 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.61 48.0 3.61e-01 83.0% 81.9%
3932690 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.61 34.0 3.76e-01 90.2% 67.8%
3956966 103.4.1.0 ↗ alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.60 42.0 4.49e-01 71.4% 98.9%
3764064 4009.1.1.0 ↗ alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.60 35.0 3.93e-01 94.6% 75.3%
3485641 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 29.0 3.48e-01 97.3% 69.3%
5011590 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.58 40.0 3.37e-01 71.4% 69.9%
5076868 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 39.0 3.26e-01 70.5% 74.0%
3546458 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.57 46.0 3.57e-01 87.5% 68.6%
3519442 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 43.0 3.89e-01 80.4% 74.8%
3203407 192.15.1.0 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.57 39.0 3.24e-01 70.5% 74.7%
None — 0.56 45.0 3.30e-01 88.4% 79.1%
5070677 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.55 37.0 3.40e-01 96.4% 51.3%
3948924 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 38.0 3.19e-01 70.5% 73.8%
3621548 5079.1.1.1 ↗ alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.55 39.0 3.12e-01 95.5% 38.1%
4983528 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 37.0 3.13e-01 71.4% 71.5%
3718378 5059.1.1.14 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › CRT-like 0.54 46.0 3.31e-01 96.4% 100.0%
4936746 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 37.0 3.17e-01 71.4% 75.4%
5004415 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.54 36.0 3.01e-01 95.5% 38.5%
4944614 1075.3.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.53 46.0 3.38e-01 95.5% 98.7%
3822713 109.22.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Survival of motor neuron protein-interacting protein 1 › Survival of motor neuron protein-interacting protein 1 › SIP1 0.52 37.0 2.96e-01 87.5% 36.1%
3253674 140.1.1.5 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.52 37.0 2.99e-01 73.2% 42.8%
4938757 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 37.0 3.44e-01 74.1% 60.0%
3707613 3877.1.1.0 ↗ alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.51 44.0 3.52e-01 99.1% 79.6%
3595656 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.51 38.0 3.63e-01 79.5% 85.9%
5026844 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.50 38.0 3.62e-01 98.2% 67.7%
3189684 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.50 40.0 2.94e-01 94.6% 32.4%
D7 medium residues 974-1059_1221-1327
PDB
Domain cluster: rep: IMGVR_UViG_3300028564_000083-3300028564-Ga0255344_100350619__D149-204_350-457
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bgxT05 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.87 49.0 6.23e-01 82.9% 89.3%
4x0qA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.79 53.0 6.20e-01 87.0% 91.6%
1jqgA01 3.30.70.340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like 0.71 33.0 4.67e-01 87.0% 92.3%
3im8A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.71 29.0 4.60e-01 81.9% 100.0%
2f1fA02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.70 28.0 4.33e-01 79.8% 91.0%
2fgcA03 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.69 27.0 4.24e-01 79.8% 90.8%
4dezA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.69 36.0 5.00e-01 78.8% 100.0%
7npaA02 3.30.70.3340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 29.0 4.31e-01 72.0% 89.4%
1s7hA02 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 31.0 4.52e-01 82.4% 98.8%
3ofgB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 32.0 4.68e-01 83.9% 100.0%
1mw7A03 3.30.70.980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain 0.66 28.0 4.36e-01 83.9% 100.0%
1vk8A00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 32.0 4.44e-01 84.5% 93.5%
1yqhA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 32.0 4.21e-01 82.9% 85.6%
5wm1A02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 37.0 4.80e-01 77.7% 100.0%
3ungC03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 41.0 4.90e-01 82.9% 93.2%
1x9mA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 51.0 5.32e-01 82.9% 91.0%
1q5yC00 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.63 29.0 4.20e-01 81.9% 100.0%
4wp3C00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.62 48.0 4.88e-01 88.6% 81.3%
1lxjA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 32.0 4.22e-01 84.5% 91.3%
5llwA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 42.0 4.98e-01 87.0% 100.0%
1azsA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.60 47.0 4.78e-01 81.9% 81.1%
5oyhD00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.59 47.0 4.81e-01 91.7% 84.9%
6zxbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.59 43.0 4.94e-01 85.0% 100.0%
6ifnA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.59 45.0 4.87e-01 79.8% 92.9%
3mtkA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.58 46.0 5.01e-01 93.3% 98.8%
1fx2A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.58 46.0 4.26e-01 81.3% 77.9%
2w01B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.58 46.0 4.58e-01 81.9% 80.2%
1y10B02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.57 44.0 4.52e-01 89.1% 82.5%
4urgA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.57 43.0 4.84e-01 84.5% 99.3%
6yiiA02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.57 45.0 4.36e-01 81.3% 79.4%
3c0wA02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.53 24.0 3.11e-01 82.9% 74.8%
3hz7A00 3.30.110.40 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › TusA-like domain 0.52 20.0 3.10e-01 92.7% 87.7%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3601652 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 48.0 6.35e-01 75.1% 100.0%
3962170 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.80 46.0 6.16e-01 71.0% 100.0%
3607581 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.80 51.0 6.42e-01 78.2% 100.0%
5077051 304.24.1.0 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.79 30.0 4.29e-01 78.8% 71.6%
3965497 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.79 39.0 5.74e-01 71.0% 100.0%
3423771 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.79 50.0 6.33e-01 71.0% 100.0%
3766383 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.79 48.0 6.25e-01 71.0% 100.0%
3407163 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.78 48.0 6.16e-01 73.6% 100.0%
3601834 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.76 43.0 5.88e-01 77.7% 100.0%
3613455 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.75 53.0 6.34e-01 78.8% 100.0%
3591785 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.74 54.0 6.12e-01 83.4% 94.7%
3608339 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.74 51.0 6.13e-01 78.8% 100.0%
3706910 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 58.0 5.77e-01 81.9% 100.0%
3405197 304.7.1.1 ↗ a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Propep_M14 0.72 32.0 4.82e-01 85.5% 100.0%
4176322 304.8.1.3 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NapD 0.70 29.0 4.46e-01 83.4% 92.5%
4995741 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.70 52.0 6.00e-01 78.8% 100.0%
3404332 304.7.1.1 ↗ a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Propep_M14 0.70 32.0 4.55e-01 87.0% 91.1%
4658950 304.117.1.1 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.69 29.0 4.54e-01 85.5% 98.7%
3486431 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.69 53.0 4.39e-01 78.2% 99.0%
3783788 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.69 52.0 4.38e-01 77.2% 98.0%
3372265 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.68 41.0 5.33e-01 74.1% 100.0%
4066007 304.11.1.2 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › SAT 0.67 27.0 4.34e-01 80.8% 97.3%
3390426 304.163.1.1 ↗ a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain › R1_ABCA1 0.67 34.0 4.59e-01 86.5% 94.0%
5011278 304.48.1.22 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.66 38.0 5.00e-01 79.3% 100.0%
3598488 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.66 47.0 5.19e-01 71.5% 100.0%
4955154 304.48.1.31 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.65 51.0 4.84e-01 80.8% 100.0%
4944833 304.48.1.31 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.65 47.0 4.90e-01 82.9% 78.9%
3638055 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.65 49.0 4.98e-01 77.7% 95.4%
4931425 304.57.1.1 ↗ a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.65 35.0 4.48e-01 70.5% 90.0%
3939563 304.57.1.0 ↗ a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like 0.65 34.0 4.51e-01 86.0% 92.4%
4335903 304.48.1.22 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.64 37.0 4.79e-01 77.2% 99.1%
4094511 304.48.1.22 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.63 38.0 4.83e-01 81.3% 100.0%
4373656 304.57.1.1 ↗ a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.63 33.0 4.21e-01 70.5% 85.2%
3182879 304.11.1.2 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › SAT 0.61 27.0 4.06e-01 81.3% 98.8%
3485236 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.61 43.0 5.06e-01 80.8% 99.3%
5036793 304.48.1.31 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.60 45.0 4.70e-01 76.7% 97.2%
4473492 304.11.1.2 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › SAT 0.60 27.0 4.01e-01 81.9% 96.5%
3739086 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.59 46.0 4.36e-01 80.8% 72.0%
4886155 304.57.1.1 ↗ a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.59 35.0 3.91e-01 70.5% 74.7%
5079089 304.48.1.31 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.58 47.0 4.77e-01 84.5% 93.8%
3286133 304.48.1.14 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.58 44.0 4.83e-01 86.0% 94.4%
139439 304.48.1.14 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.58 46.0 5.01e-01 93.3% 98.8%
5005971 304.48.1.31 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.58 51.0 3.45e-01 92.2% 62.9%
3288882 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.58 52.0 4.74e-01 94.3% 85.7%
3968679 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.58 27.0 3.76e-01 78.8% 89.5%
5079712 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.57 45.0 3.88e-01 80.3% 91.2%
4513958 304.48.1.31 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.57 44.0 4.25e-01 78.8% 100.0%
2120642 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.57 40.0 4.70e-01 74.1% 100.0%
4652155 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.57 44.0 4.25e-01 81.3% 70.9%
5022760 304.48.1.31 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.56 49.0 3.72e-01 91.2% 83.0%
5022740 304.48.1.31 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.56 45.0 4.41e-01 83.9% 83.8%
3168619 304.8.1.7 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ALS_ss_C 0.53 34.0 3.98e-01 81.9% 90.4%
3960399 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.53 46.0 4.37e-01 91.7% 78.6%
5037904 304.48.1.31 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.52 45.0 4.20e-01 90.7% 91.1%
3413344 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.52 45.0 4.19e-01 91.7% 74.2%
3718665 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.50 20.0 2.83e-01 77.2% 76.5%
D8 medium residues 1060-1217
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00476.27 best DNA_pol_A 50.5 2.10e-13 74.7% 28.1%
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4xviA01 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.85 64.0 6.68e-01 100.0% 84.0%
7pbkB02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.76 52.0 5.65e-01 98.1% 81.5%
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.75 56.0 5.88e-01 100.0% 84.7%
4x0qA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.73 55.0 5.77e-01 100.0% 85.4%
7r0kA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.69 59.0 5.87e-01 98.7% 86.7%
5f64A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 29.0 4.07e-01 100.0% 86.7%
1aisB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.62 30.0 3.77e-01 93.0% 75.5%
5xsoA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 27.0 3.76e-01 100.0% 88.2%
1p4wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 27.0 3.55e-01 98.1% 77.0%
3cdhA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 27.0 2.99e-01 83.5% 55.2%
2p6rA03 1.10.3380.30 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › 0.50 38.0 3.40e-01 97.5% 56.9%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3386797 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 63.0 5.49e-01 100.0% 51.8%
3562851 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.85 60.0 6.26e-01 95.6% 77.9%
4876668 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.85 60.0 6.79e-01 95.6% 92.7%
3711347 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.85 60.0 6.42e-01 96.2% 82.1%
3969341 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.85 60.0 6.70e-01 95.6% 91.2%
4217329 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.84 57.0 6.45e-01 93.7% 89.2%
4169333 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.84 57.0 6.42e-01 94.3% 88.0%
4456463 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.83 60.0 6.53e-01 96.8% 88.5%
3483301 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.83 57.0 5.86e-01 94.3% 73.3%
3595356 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.83 58.0 6.50e-01 94.9% 90.4%
3333780 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.82 58.0 6.15e-01 94.9% 80.7%
3259994 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.81 53.0 5.87e-01 94.3% 80.8%
4024558 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.80 53.0 5.68e-01 96.2% 75.7%
2579554 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.79 55.0 5.73e-01 94.3% 75.7%
3423772 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.78 55.0 6.31e-01 93.7% 97.4%
3704770 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.76 56.0 6.11e-01 94.9% 91.5%
3277186 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.76 53.0 5.89e-01 93.0% 89.6%
4237263 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.75 50.0 5.70e-01 95.6% 88.3%
4617703 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.75 60.0 6.36e-01 95.6% 92.9%
3718521 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.75 57.0 6.10e-01 94.9% 91.9%
3581048 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.74 55.0 5.55e-01 100.0% 77.4%
4848450 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.73 50.0 5.36e-01 92.4% 79.1%
2970332 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.73 52.0 5.44e-01 94.9% 79.7%
4995740 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.69 45.0 5.02e-01 98.1% 84.0%
3654151 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.69 57.0 5.66e-01 94.3% 83.6%
3595646 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.66 52.0 5.28e-01 94.9% 83.9%
3703169 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.65 57.0 5.71e-01 95.6% 91.3%
3601930 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.65 59.0 5.57e-01 97.5% 82.7%
3279610 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.61 41.0 4.72e-01 94.3% 93.0%