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MW862109.1__QVW29077.1__Medea1_0010__00010

Bact-Vir

MW862109.1__QVW29077.1__Medea1_0010__00010

Identity

Accession:
MW862109 ↗
Kingdom:
phage

Quality

79.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 39-149
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF09669.16 best Phage_pRha 76.5 2.70e-21 76.6% 98.9%
D2 high residues 153-215
PDB
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1k32A03 3.30.750.44 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › 0.67 56.0 5.42e-01 98.4% 81.9%
7wu8B01 1.20.1160.20 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › 0.65 39.0 3.61e-01 76.2% 46.8%
1or7B01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.65 58.0 5.07e-01 100.0% 72.3%
2o7gA00 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.65 57.0 5.13e-01 100.0% 77.3%
7r8bB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 51.0 3.44e-01 95.2% 24.5%
3qkaE02 1.10.287.2460 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 38.0 4.30e-01 73.0% 88.4%
3deeA01 1.10.150.690 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 0.62 51.0 4.62e-01 100.0% 67.4%
2a7oA00 1.10.1740.100 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Set2, Rpb1 interacting domain 0.61 52.0 4.57e-01 100.0% 77.0%
7kfuC02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.61 51.0 3.58e-01 100.0% 47.6%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.60 43.0 4.07e-01 76.2% 69.2%
3ckdA02 1.20.58.360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines 0.59 47.0 3.87e-01 90.5% 53.2%
5kjpA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.58 43.0 4.52e-01 81.0% 100.0%
3t0yA01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.58 48.0 4.82e-01 100.0% 93.9%
7ar7E01 1.10.10.1590 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E 0.57 35.0 3.50e-01 73.0% 58.7%
2zgyA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 40.0 3.13e-01 74.6% 100.0%
3kbbA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.56 37.0 3.65e-01 100.0% 61.4%
2qvwB05 1.10.1740.150 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.56 36.0 3.45e-01 95.2% 55.3%
6ofsA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.55 48.0 3.35e-01 100.0% 42.9%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.55 39.0 3.66e-01 76.2% 63.3%
3o8jA02 1.10.230.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450-Terp; domain 2 › Cytochrome P450-Terp, domain 2 0.55 42.0 3.71e-01 100.0% 55.6%
1jr8A00 1.20.120.310 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain 0.54 39.0 3.33e-01 76.2% 74.3%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.53 42.0 4.23e-01 100.0% 90.9%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 43.0 3.77e-01 98.4% 95.1%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.50 39.0 3.59e-01 85.7% 96.5%
7y8uF01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.50 38.0 2.83e-01 87.3% 50.5%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3589701 632.24.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › GBS CAMP factor C-terminal domain › GBS CAMP factor C-terminal domain › ORF6C 0.87 79.0 7.07e-01 100.0% 83.5%
3387918 207.9.1.3 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pentapeptide repeats › Pentapeptide repeats › Pentapeptide_3 0.74 67.0 4.20e-01 100.0% 20.3%
3853866 558.1.1.14 alpha duplicates or obligate multimers › Lis-homology dimerization domain › Lis-homology dimerization domain › Lis-homology dimerization domain › HRI2_3H 0.74 52.0 5.09e-01 74.6% 68.6%
4364892 101.1.2.309 alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.74 66.0 4.27e-01 100.0% 93.2%
4682562 101.1.2.309 alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.74 67.0 4.70e-01 100.0% 55.1%
4995195 2488.1.1.1 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase 0.73 60.0 4.06e-01 100.0% 24.7%
3596205 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.72 64.0 5.57e-01 100.0% 69.5%
5044325 4125.1.1.0 alpha superhelices › BH3980-like › BH3980-like › BH3980-like 0.71 57.0 5.71e-01 90.5% 86.2%
3328865 3788.1.1.0 alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) 0.71 63.0 6.09e-01 98.4% 98.6%
4394038 148.1.3.3 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PCP_red 0.71 57.0 5.88e-01 98.4% 93.3%
3717011 524.1.1.1 alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC 0.71 55.0 3.98e-01 100.0% 30.3%
3800950 188.1.1.0 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain 0.70 49.0 3.38e-01 74.6% 37.7%
4495994 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.69 59.0 3.88e-01 98.4% 25.2%
5060948 4957.1.1.9 a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit › HAAS 0.66 55.0 5.26e-01 93.7% 88.0%
3951865 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.66 59.0 4.89e-01 100.0% 61.8%
4814 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.66 58.0 4.80e-01 100.0% 60.2%
3951200 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.65 58.0 5.05e-01 100.0% 71.6%
3406381 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.65 56.0 3.96e-01 100.0% 32.4%
3269012 2004.1.1.417 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, AAA_21 0.65 51.0 3.32e-01 88.9% 19.7%
4120292 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.65 48.0 4.43e-01 79.4% 70.0%
4589278 101.1.2.309 alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.64 57.0 4.83e-01 100.0% 95.2%
4034078 5054.1.1.6 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH 0.63 49.0 4.27e-01 85.7% 75.0%
3993765 627.1.1.0 alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain 0.62 42.0 3.91e-01 79.4% 54.1%
4220382 5054.1.1.6 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH 0.61 48.0 4.06e-01 87.3% 69.1%
4031187 632.19.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 0.61 53.0 5.07e-01 98.4% 93.3%
5055153 3290.1.1.0 alpha complex topology › Cytosolic helical domain in ferrous iron transport protein B › Cytosolic helical domain in ferrous iron transport protein B › Cytosolic helical domain in ferrous iron transport protein B 0.61 42.0 3.96e-01 74.6% 83.7%
3594407 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.60 52.0 4.75e-01 100.0% 76.5%
3622208 633.24.1.2 alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › DUF5601 0.59 42.0 3.59e-01 76.2% 54.3%
3719792 4030.1.1.0 alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.58 41.0 4.18e-01 77.8% 73.3%
3465214 103.4.1.5 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX_2 0.57 47.0 4.49e-01 100.0% 87.5%
3955184 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.57 49.0 4.53e-01 100.0% 80.0%
4947266 7583.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in AF1104-like proteins › Rossmann-like domain in AF1104-like proteins › Rossmann-like domain in AF1104-like proteins › ARMT1-like_dom 0.56 46.0 3.28e-01 96.8% 28.6%
4001318 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.56 41.0 3.89e-01 77.8% 77.3%
3243299 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.55 40.0 3.89e-01 77.8% 74.3%
3711247 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.54 44.0 2.80e-01 90.5% 91.4%
4242867 544.1.1.2 alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › SRA1 0.54 46.0 3.78e-01 100.0% 78.4%
5032045 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.53 38.0 3.21e-01 74.6% 56.0%
3315663 601.23.1.0 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.52 45.0 3.05e-01 100.0% 50.6%
3545183 148.1.3.364 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PF28256 0.52 40.0 3.37e-01 88.9% 46.7%
4181805 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.50 34.0 3.25e-01 77.8% 57.7%
D3 high residues 238-299
PDB
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2kgfA00 1.10.375.10 Mainly Alpha › Orthogonal Bundle › Human Immunodeficiency Virus Type 1 Capsid Protein › Human Immunodeficiency Virus Type 1 Capsid Protein 0.71 50.0 3.83e-01 74.2% 38.6%
4wksC02 2.30.120.10 Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region 0.61 34.0 3.18e-01 80.6% 44.0%
2arpF02 3.30.60.30 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.59 31.0 2.95e-01 96.8% 40.3%
7kfuC02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.55 45.0 3.07e-01 90.3% 75.1%
5c9iD01 1.10.439.10 Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Penicillin Amidohydrolase, domain 1 0.55 42.0 3.08e-01 93.5% 31.7%
2v3sA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.50 35.0 3.10e-01 74.2% 56.2%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3444901 4954.1.1.0 a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit 0.67 44.0 3.15e-01 100.0% 24.0%
4011910 633.23.1.9 alpha bundles › Bromodomain-like › Claudin › Claudin › SUR7 0.61 42.0 2.91e-01 72.6% 95.2%
4922053 5093.1.1.4 a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly, Fibritin_C 0.58 39.0 2.35e-01 71.0% 91.2%
3213226 3075.1.1.0 a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA 0.58 41.0 4.06e-01 74.2% 86.2%
3877696 101.1.2.164 alpha arrays › HTH › HTH › winged helix domain › TFA2_Winged_2 0.57 37.0 3.20e-01 100.0% 42.0%
4059525 218.1.1.8 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.55 39.0 3.40e-01 74.2% 54.7%
3743175 630.1.1.0 a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain 0.55 44.0 3.31e-01 100.0% 33.3%
3749416 2007.15.1.11 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › MAP3K_TRAF_bd 0.55 43.0 2.81e-01 93.5% 52.8%
3351840 284.1.3.2 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › OSR1_C 0.54 37.0 3.68e-01 74.2% 78.3%
3994831 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.53 43.0 2.79e-01 90.3% 55.4%
3468880 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 44.0 2.74e-01 93.5% 25.6%
3890428 109.3.1.96 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.51 42.0 3.09e-01 93.5% 78.3%