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MZ447858.1__UAW01121.1__X__00014

Bact-Vir

MZ447858.1__UAW01121.1__X__00014

Identity

Accession:
MZ447858 ↗
Kingdom:
phage

Quality

90.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-65
PDB
Domain cluster: representative
CATH (94)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ha8A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.94 82.0 8.24e-01 100.0% 92.1%
2qlzA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.88 72.0 7.23e-01 100.0% 87.3%
3cuqA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.84 76.0 6.94e-01 100.0% 90.1%
3gw2A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.83 69.0 6.02e-01 100.0% 61.3%
2l01A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.83 71.0 6.64e-01 100.0% 76.6%
3majA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.83 65.0 6.66e-01 98.4% 88.3%
4nb5B01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.83 75.0 6.70e-01 100.0% 72.9%
2vxzA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.82 68.0 6.71e-01 100.0% 86.4%
1qbjC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.82 71.0 6.98e-01 100.0% 90.9%
4kmfA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.81 66.0 6.71e-01 100.0% 91.9%
5jbrA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.80 70.0 6.30e-01 100.0% 70.9%
1ku9B01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.80 70.0 6.28e-01 100.0% 70.1%
4wcgA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.79 65.0 6.58e-01 100.0% 91.8%
1yyvB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.79 70.0 5.72e-01 100.0% 54.5%
2fa5A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.79 60.0 4.66e-01 100.0% 37.4%
5eriA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.79 69.0 5.13e-01 100.0% 39.9%
1s3jA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.79 69.0 6.87e-01 100.0% 95.3%
3cjnA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.79 66.0 5.03e-01 100.0% 40.4%
2qvoA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 68.0 6.15e-01 100.0% 71.3%
2obpA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 69.0 6.40e-01 100.0% 80.2%
4xrfA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 68.0 5.18e-01 100.0% 43.0%
3k69A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 65.0 4.93e-01 100.0% 39.3%
3bpvA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 67.0 5.19e-01 100.0% 44.5%
3r0aA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 68.0 5.54e-01 100.0% 54.2%
3g3zA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 67.0 6.76e-01 100.0% 95.3%
1ub9A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 67.0 5.73e-01 100.0% 61.0%
2mlgA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 69.0 6.41e-01 100.0% 80.5%
1sfxB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 66.0 5.65e-01 100.0% 58.7%
5f7qC01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 68.0 6.62e-01 98.4% 90.0%
1xmkA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 64.0 5.97e-01 100.0% 73.4%
6oinA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.76 61.0 6.03e-01 100.0% 80.6%
2xubA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.76 64.0 5.99e-01 100.0% 75.6%
1ulyA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.76 66.0 5.91e-01 100.0% 69.7%
6pcoC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.76 65.0 5.14e-01 100.0% 46.2%
3bz6A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 67.0 6.26e-01 100.0% 84.6%
2zkzC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 61.0 5.51e-01 100.0% 65.5%
4hw0C00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 59.0 5.28e-01 100.0% 60.2%
1z6tA04 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 64.0 5.82e-01 100.0% 71.8%
3ke2B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 66.0 5.68e-01 100.0% 63.5%
2jt1A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 66.0 6.37e-01 100.0% 93.0%
1p4xA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 65.0 5.20e-01 100.0% 49.6%
5hs7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 64.0 5.54e-01 100.0% 62.2%
4em2A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 64.0 4.84e-01 100.0% 40.7%
2fbhA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 65.0 5.06e-01 100.0% 45.3%
1ucrB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 65.0 6.17e-01 100.0% 84.0%
2bv6A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 63.0 4.97e-01 100.0% 44.9%
2nyxB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 63.0 4.87e-01 100.0% 43.0%
7dvrA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 63.0 4.94e-01 98.4% 46.8%
1jgsA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 63.0 4.89e-01 100.0% 44.2%
3cuqA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 61.0 5.72e-01 100.0% 73.8%
2b0lC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 63.0 5.61e-01 100.0% 67.0%
1yj7B01 3.30.70.1530 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hypothetical protein rpa1041 0.73 47.0 4.60e-01 79.4% 59.2%
2fbiA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 62.0 4.88e-01 100.0% 44.9%
2hoeA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 59.0 6.15e-01 100.0% 100.0%
2lycA00 1.10.10.1890 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ska1 microtubule binding domain-like 0.72 62.0 4.98e-01 100.0% 76.2%
1u5tA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 58.0 5.69e-01 100.0% 83.1%
3m8eA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 62.0 5.34e-01 100.0% 61.4%
6az1a00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 58.0 5.64e-01 100.0% 81.9%
3eyyA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 62.0 5.72e-01 100.0% 78.0%
6kf9G01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 61.0 5.65e-01 100.0% 78.0%
5e1wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 59.0 4.40e-01 100.0% 36.3%
2vqcA00 1.10.10.1470 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › F-112 protein-like 0.70 60.0 5.89e-01 100.0% 90.0%
4a6dA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 58.0 5.21e-01 100.0% 64.9%
4rayA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 60.0 5.50e-01 100.0% 75.3%
3l7wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 59.0 5.08e-01 100.0% 61.9%
3szpA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 58.0 5.16e-01 100.0% 66.3%
4ejoA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 58.0 4.91e-01 100.0% 58.0%
2pg4A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 57.0 5.20e-01 100.0% 71.4%
2cveA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 42.0 4.17e-01 81.0% 60.6%
4c9yA00 1.10.10.1890 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ska1 microtubule binding domain-like 0.64 55.0 4.51e-01 100.0% 75.6%
5nl9A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 57.0 5.17e-01 100.0% 75.0%
1js3A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.62 48.0 4.23e-01 85.7% 67.0%
2lrrA00 3.30.1370.50 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain 0.62 51.0 5.03e-01 100.0% 87.1%
6i7dB01 6.20.240.20 Special › Other non-globular › Alpha-Beta Plaits › 0.62 44.0 4.56e-01 79.4% 81.4%
5hvqC01 3.90.1150.220 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.62 51.0 4.87e-01 100.0% 91.3%
3hz7A00 3.30.110.40 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › TusA-like domain 0.61 51.0 4.92e-01 100.0% 82.2%
4e1oA03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.61 48.0 4.16e-01 85.7% 66.3%
2mh9A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 53.0 4.26e-01 100.0% 78.0%
2gukA00 3.30.2190.10 Alpha Beta › 2-Layer Sandwich › PG1857-like › PG1857-like 0.60 50.0 4.27e-01 100.0% 55.9%
1dq3A04 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.60 51.0 4.29e-01 100.0% 65.8%
3ez2A01 1.10.1660.30 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.57 43.0 4.20e-01 81.0% 74.3%
3zieD00 3.30.110.150 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › SepF-like protein 0.57 48.0 4.49e-01 100.0% 75.6%
2axyA00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.56 40.0 3.92e-01 79.4% 68.1%
2pcrA02 3.40.190.80 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › 0.56 48.0 3.95e-01 100.0% 53.0%
2anrA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.54 39.0 3.74e-01 81.0% 66.7%
2pt7G02 3.30.1370.180 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.54 43.0 4.34e-01 100.0% 92.5%
3ezjA02 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.53 38.0 3.74e-01 85.7% 72.1%
5i2cB01 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.53 45.0 3.43e-01 95.2% 81.5%
4a5pB01 3.40.30.60 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › FHIPEP family, domain 1 0.52 37.0 3.00e-01 77.8% 97.6%
1s2oA02 3.90.1070.10 Alpha Beta › Alpha-Beta Complex › Hypothetical Protein Ta0175; Chain: A, domain 2 › 0.51 41.0 4.08e-01 98.4% 91.5%
1gkxA01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.51 44.0 3.39e-01 100.0% 85.4%
2g47A03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.50 39.0 2.72e-01 84.1% 33.0%
5idmA00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.50 42.0 3.14e-01 98.4% 66.7%
2ab5A02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.50 43.0 3.42e-01 96.8% 84.3%
ECOD (100)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3288015 101.1.2.92 alpha arrays › HTH › HTH › winged helix domain › HTH_11 0.87 74.0 7.11e-01 100.0% 81.4%
3286661 101.1.2.92 alpha arrays › HTH › HTH › winged helix domain › HTH_11 0.87 75.0 5.81e-01 100.0% 46.4%
4031524 101.1.2.92 alpha arrays › HTH › HTH › winged helix domain › HTH_11 0.87 74.0 7.40e-01 100.0% 89.2%
3587558 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.86 72.0 6.94e-01 100.0% 80.0%
3281272 101.1.2.92 alpha arrays › HTH › HTH › winged helix domain › HTH_11 0.86 74.0 5.77e-01 100.0% 46.4%
5079074 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.84 71.0 5.82e-01 100.0% 52.7%
5043670 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.83 70.0 6.79e-01 100.0% 82.9%
140413 101.1.2.128 alpha arrays › HTH › HTH › winged helix domain › DUF2582 0.83 71.0 6.91e-01 100.0% 85.5%
3961630 101.1.2.456 alpha arrays › HTH › HTH › winged helix domain › HTH_MmpR5 0.82 74.0 5.41e-01 100.0% 38.7%
5010793 101.1.2.15 alpha arrays › HTH › HTH › winged helix domain › MarR 0.82 70.0 6.66e-01 100.0% 80.0%
4965139 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.82 71.0 6.53e-01 100.0% 75.0%
1296342 101.1.2.456 alpha arrays › HTH › HTH › winged helix domain › HTH_MmpR5 0.82 74.0 5.50e-01 100.0% 42.2%
5065234 101.1.2.110 alpha arrays › HTH › HTH › winged helix domain › HTH_IclR 0.81 71.0 6.17e-01 100.0% 64.2%
3510030 101.1.2.678 alpha arrays › HTH › HTH › winged helix domain › PheRS_DBD1, PheRS_DBD3, PheRS_DBD2 0.81 73.0 5.09e-01 100.0% 88.2%
4951142 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.81 71.0 5.53e-01 100.0% 46.9%
5057532 101.1.2.893 alpha arrays › HTH › HTH › winged helix domain › DUF2226 0.81 70.0 4.47e-01 100.0% 21.2%
None 0.81 70.0 4.19e-01 100.0% 14.4%
2583 101.1.2.231 alpha arrays › HTH › HTH › winged helix domain › Staph_reg_Sar_Rot 0.80 72.0 5.87e-01 100.0% 54.8%
3461891 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.80 69.0 5.89e-01 100.0% 60.0%
5067775 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.80 68.0 6.12e-01 100.0% 69.4%
5049143 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.80 69.0 5.70e-01 100.0% 54.5%
5078611 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.80 68.0 6.19e-01 100.0% 70.6%
5082453 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.80 72.0 6.36e-01 100.0% 71.1%
5050479 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.80 70.0 6.27e-01 100.0% 70.0%
5029321 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.80 68.0 4.90e-01 100.0% 34.7%
5029842 101.1.2.645 alpha arrays › HTH › HTH › winged helix domain › HTH_40 0.79 72.0 6.01e-01 100.0% 61.0%
5053163 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.79 68.0 6.61e-01 100.0% 85.7%
5032450 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.79 68.0 5.88e-01 100.0% 61.0%
5008107 101.1.2.15 alpha arrays › HTH › HTH › winged helix domain › MarR 0.79 70.0 5.86e-01 100.0% 59.0%
5058409 101.1.2.110 alpha arrays › HTH › HTH › winged helix domain › HTH_IclR 0.79 69.0 6.22e-01 100.0% 71.8%
4076677 101.1.2.63 alpha arrays › HTH › HTH › winged helix domain › FaeA 0.78 67.0 6.37e-01 100.0% 80.0%
3703137 101.1.2.68 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc34 0.78 70.0 6.78e-01 100.0% 90.0%
5024520 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.78 67.0 5.56e-01 100.0% 54.5%
4946834 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.78 70.0 6.82e-01 100.0% 91.4%
5049144 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.78 67.0 4.44e-01 100.0% 24.6%
5082589 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.78 66.0 6.11e-01 100.0% 73.8%
5040012 101.1.2.135 alpha arrays › HTH › HTH › winged helix domain › MarR_2 0.78 67.0 5.97e-01 100.0% 67.8%
4031479 101.1.2.231 alpha arrays › HTH › HTH › winged helix domain › Staph_reg_Sar_Rot 0.78 69.0 5.67e-01 100.0% 56.5%
5033276 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.78 66.0 4.94e-01 100.0% 39.1%
5073786 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.78 66.0 5.76e-01 100.0% 62.8%
4945701 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.78 68.0 6.16e-01 98.4% 77.6%
4951265 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.78 69.0 6.72e-01 100.0% 91.4%
5080526 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.78 67.0 5.44e-01 100.0% 52.2%
5046546 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.78 65.0 4.41e-01 100.0% 25.7%
4997333 101.1.2.44 alpha arrays › HTH › HTH › winged helix domain › Ribosomal_S25 0.77 65.0 6.16e-01 100.0% 78.7%
5016457 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.77 66.0 6.03e-01 100.0% 71.8%
3944893 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.77 65.0 5.67e-01 100.0% 62.1%
2588 101.1.2.143 alpha arrays › HTH › HTH › winged helix domain › HTH_34 0.77 67.0 5.73e-01 100.0% 61.0%
4927119 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.77 67.0 6.69e-01 98.4% 96.9%
3593500 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.77 69.0 5.84e-01 100.0% 62.0%
4998981 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.77 67.0 6.15e-01 100.0% 74.1%
5058434 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.77 65.0 5.10e-01 100.0% 45.4%
4996260 101.1.2.135 alpha arrays › HTH › HTH › winged helix domain › MarR_2 0.77 69.0 5.12e-01 100.0% 40.6%
3685818 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.76 67.0 6.51e-01 100.0% 94.3%
3781962 101.1.2.68 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc34 0.76 66.0 6.61e-01 100.0% 95.4%
5028550 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.76 64.0 5.17e-01 100.0% 48.0%
3286591 101.1.2.612 alpha arrays › HTH › HTH › winged helix domain › MarR_2, PF27059 0.76 68.0 5.08e-01 100.0% 41.6%
4970012 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.76 67.0 5.80e-01 100.0% 63.0%
5039088 101.1.2.110 alpha arrays › HTH › HTH › winged helix domain › HTH_IclR 0.76 64.0 4.88e-01 100.0% 40.7%
4022243 101.1.2.517 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD 0.76 65.0 3.79e-01 100.0% 11.9%
3194355 101.1.2.517 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD 0.76 65.0 3.75e-01 100.0% 10.9%
4443506 101.1.2.517 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD 0.76 64.0 3.90e-01 100.0% 14.9%
5055904 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.76 67.0 5.50e-01 100.0% 54.8%
3923802 101.1.2.278 alpha arrays › HTH › HTH › winged helix domain › CNDH2_C 0.75 66.0 5.80e-01 100.0% 65.3%
4946715 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.75 63.0 6.28e-01 100.0% 90.8%
4962220 101.1.2.141 alpha arrays › HTH › HTH › winged helix domain › HTH_24 0.75 64.0 5.88e-01 100.0% 73.8%
4975296 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.75 62.0 6.21e-01 100.0% 90.8%
4961776 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.74 64.0 5.55e-01 100.0% 62.0%
3601862 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.74 65.0 3.90e-01 100.0% 14.3%
4954067 101.1.2.92 alpha arrays › HTH › HTH › winged helix domain › HTH_11 0.74 66.0 6.61e-01 100.0% 100.0%
3654518 101.1.2.288 alpha arrays › HTH › HTH › winged helix domain › Stk19 0.74 64.0 5.37e-01 98.4% 65.5%
5079941 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.74 64.0 6.04e-01 100.0% 81.3%
5074186 101.1.2.44 alpha arrays › HTH › HTH › winged helix domain › Ribosomal_S25 0.74 65.0 5.61e-01 100.0% 63.0%
4944823 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.74 62.0 5.99e-01 96.8% 84.3%
5081044 101.1.2.26 alpha arrays › HTH › HTH › winged helix domain › HxlR 0.73 60.0 5.46e-01 100.0% 66.3%
3494294 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.73 63.0 6.01e-01 100.0% 83.6%
3431562 101.1.2.57 alpha arrays › HTH › HTH › winged helix domain › EAP30 0.73 62.0 5.75e-01 100.0% 75.0%
4937481 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.73 61.0 5.11e-01 100.0% 53.6%
4559973 101.1.2.44 alpha arrays › HTH › HTH › winged helix domain › Ribosomal_S25 0.73 64.0 5.55e-01 100.0% 63.0%
4980177 101.1.2.150 alpha arrays › HTH › HTH › winged helix domain › HTH_45 0.73 61.0 4.96e-01 100.0% 49.2%
5043785 101.1.2.44 alpha arrays › HTH › HTH › winged helix domain › Ribosomal_S25 0.73 64.0 6.22e-01 100.0% 90.0%
3848679 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.72 63.0 4.81e-01 100.0% 42.0%
5031411 101.1.2.136 alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.72 61.0 5.72e-01 100.0% 77.5%
5048985 101.1.2.650 alpha arrays › HTH › HTH › winged helix domain › DUF7343 0.72 61.0 6.07e-01 100.0% 92.3%
5046509 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.71 62.0 5.89e-01 100.0% 85.3%
3500170 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.71 62.0 5.54e-01 100.0% 70.0%
4972274 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.71 61.0 5.99e-01 100.0% 92.9%
5016572 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.71 58.0 5.29e-01 100.0% 66.7%
3842720 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.70 58.0 5.39e-01 93.7% 87.5%
4444948 101.1.2.44 alpha arrays › HTH › HTH › winged helix domain › Ribosomal_S25 0.70 61.0 5.66e-01 100.0% 78.8%
5075809 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.70 60.0 3.95e-01 100.0% 22.3%
4946823 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.69 59.0 5.64e-01 98.4% 84.0%
4987328 101.1.2.26 alpha arrays › HTH › HTH › winged helix domain › HxlR 0.69 57.0 5.24e-01 100.0% 69.4%
4945186 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.69 59.0 4.76e-01 100.0% 48.5%
5032271 101.1.2.44 alpha arrays › HTH › HTH › winged helix domain › Ribosomal_S25 0.68 59.0 5.50e-01 100.0% 78.8%
5036782 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 58.0 5.74e-01 100.0% 95.7%
None 0.68 56.0 3.37e-01 96.8% 12.4%
3524337 101.1.2.288 alpha arrays › HTH › HTH › winged helix domain › Stk19 0.67 57.0 5.34e-01 98.4% 87.5%
3642043 101.1.2.245 alpha arrays › HTH › HTH › winged helix domain › PORR 0.67 57.0 4.43e-01 100.0% 42.8%
3671580 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.66 55.0 5.35e-01 96.8% 95.7%
D2 high residues 70-186
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00186.25 best DHFR_1 64.8 1.00e-17 99.2% 78.6%
CATH (67)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ix9A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.93 89.0 7.71e-01 100.0% 79.5%
5eccA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.93 89.0 7.89e-01 100.0% 83.4%
1juvA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.92 87.0 7.18e-01 100.0% 85.0%
1j3jB00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.91 88.0 6.90e-01 100.0% 81.9%
6pf8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.91 87.0 7.36e-01 100.0% 83.5%
3k2hA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.90 86.0 7.18e-01 100.0% 80.7%
2w9hA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.90 87.0 7.68e-01 100.0% 80.9%
1bozA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.90 86.0 7.17e-01 100.0% 80.6%
3nzbX00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.90 85.0 6.86e-01 100.0% 75.2%
1ao8A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.89 84.0 7.35e-01 99.1% 81.5%
4eckA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.88 84.0 7.13e-01 100.0% 85.5%
1dhiA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.88 84.0 7.42e-01 100.0% 81.1%
2aznA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.88 83.0 6.57e-01 100.0% 88.1%
1vdrA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.87 82.0 7.36e-01 100.0% 85.4%
2hxvA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.87 83.0 6.76e-01 100.0% 89.4%
2p4gA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.87 82.0 6.23e-01 100.0% 82.7%
3zpgA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.87 82.0 6.52e-01 100.0% 84.7%
1cz3B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.87 82.0 7.14e-01 100.0% 83.3%
2b3zA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.87 82.0 6.42e-01 100.0% 85.3%
2g6vA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.85 80.0 6.29e-01 100.0% 85.6%
2xw7A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.84 78.0 6.74e-01 100.0% 85.1%
3ky8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.84 79.0 6.77e-01 100.0% 87.9%
3kgyA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.83 78.0 6.19e-01 100.0% 86.7%
4xt6A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.83 78.0 6.01e-01 100.0% 79.7%
3jtwA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.81 75.0 6.50e-01 100.0% 84.7%
2gd9A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.78 72.0 6.33e-01 100.0% 88.0%
2c0cA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.67 50.0 4.36e-01 78.6% 86.6%
3eyeA00 3.40.35.10 Alpha Beta › 3-Layer(aba) Sandwich › Fructose Permease › Phosphotransferase system, sorbose subfamily IIB component 0.61 55.0 5.06e-01 100.0% 86.3%
1bleA00 3.40.35.10 Alpha Beta › 3-Layer(aba) Sandwich › Fructose Permease › Phosphotransferase system, sorbose subfamily IIB component 0.60 53.0 4.85e-01 100.0% 82.0%
1c4kA01 3.40.50.220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 38.0 4.00e-01 70.1% 70.5%
2gzaB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 50.0 4.14e-01 91.5% 70.0%
1t6t200 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.60 49.0 5.09e-01 90.6% 95.5%
5t5dA00 3.40.35.10 Alpha Beta › 3-Layer(aba) Sandwich › Fructose Permease › Phosphotransferase system, sorbose subfamily IIB component 0.59 52.0 4.85e-01 100.0% 84.0%
1euhA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.59 43.0 3.31e-01 76.9% 58.8%
1xr4B01 3.40.1080.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaconate Coenzyme A-transferase › Glutaconate Coenzyme A-transferase 0.58 50.0 4.02e-01 94.9% 75.0%
3nutC01 3.40.1010.10 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › Tetrapyrrole methylase, N-terminal domain 0.58 51.0 5.16e-01 95.7% 98.2%
2xauA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 48.0 3.86e-01 89.7% 69.4%
6c49A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 46.0 4.22e-01 84.6% 74.5%
3e8mA00 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.58 51.0 4.62e-01 100.0% 77.4%
2pl3A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 49.0 3.99e-01 96.6% 66.4%
3h5lA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 46.0 4.15e-01 88.0% 76.4%
3pqaB01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.56 46.0 3.51e-01 87.2% 64.3%
4a8jB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 50.0 4.08e-01 98.3% 78.2%
4bucA03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.56 44.0 4.27e-01 82.9% 93.8%
4ymxA02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.56 39.0 4.28e-01 87.2% 91.3%
1j6uA03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.55 42.0 4.12e-01 82.1% 84.8%
7bmfA01 3.90.1640.30 Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › 0.54 45.0 3.90e-01 90.6% 71.9%
2xryA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.54 43.0 4.06e-01 86.3% 86.5%
3fojA00 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.54 40.0 4.27e-01 94.0% 91.9%
6i6lA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 46.0 3.65e-01 94.0% 82.0%
7lgnB03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.54 42.0 3.99e-01 82.9% 97.1%
1e8cB03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.54 40.0 3.81e-01 79.5% 95.1%
2e6xA00 3.10.20.570 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Protein of unknown function DUF3248 0.54 25.0 3.09e-01 88.9% 69.1%
4myrC00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 36.0 3.59e-01 70.1% 77.0%
4zemA02 3.40.50.10470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2 0.53 47.0 4.18e-01 100.0% 80.4%
5dcaA09 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 44.0 3.71e-01 94.9% 61.0%
2iyeA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.52 44.0 4.07e-01 100.0% 71.3%
3dmyA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 44.0 4.16e-01 93.2% 95.1%
3thxB05 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 45.0 3.51e-01 95.7% 68.1%
5iceA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 44.0 3.50e-01 94.9% 85.7%
3dqpA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 42.0 3.52e-01 90.6% 70.6%
2wq7A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.52 41.0 3.96e-01 88.0% 97.1%
1fp1D02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 43.0 3.50e-01 93.2% 83.0%
3vkhB07 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 42.0 3.60e-01 88.9% 79.4%
4l69A02 3.40.1280.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain 0.51 40.0 3.60e-01 88.0% 86.4%
4i1sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 38.0 3.83e-01 89.7% 80.2%
2y6pB00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.50 41.0 3.37e-01 91.5% 94.8%
ECOD (80)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
137968 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.93 89.0 7.71e-01 100.0% 79.5%
4315799 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.92 88.0 7.50e-01 100.0% 81.1%
4279950 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.92 88.0 7.68e-01 100.0% 80.6%
4392683 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.92 88.0 7.64e-01 100.0% 84.8%
169540 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.92 88.0 7.63e-01 100.0% 78.3%
4624802 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 88.0 7.67e-01 100.0% 81.6%
4183099 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 88.0 7.36e-01 100.0% 82.2%
4667474 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 86.0 7.27e-01 99.1% 82.2%
3963884 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 87.0 7.67e-01 100.0% 81.9%
4563316 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 87.0 7.58e-01 100.0% 80.0%
4276639 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 87.0 7.48e-01 100.0% 78.2%
3263045 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 87.0 7.02e-01 100.0% 78.0%
3900511 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.91 86.0 7.22e-01 100.0% 80.5%
2503171 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 87.0 7.31e-01 100.0% 82.1%
4228699 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 87.0 7.02e-01 100.0% 77.0%
4392834 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 86.0 6.68e-01 100.0% 80.4%
4652224 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 87.0 7.54e-01 100.0% 80.5%
3593841 7501.1.1.0 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.90 86.0 6.73e-01 100.0% 78.2%
3360231 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 86.0 6.73e-01 100.0% 68.6%
4402042 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 86.0 7.14e-01 100.0% 81.1%
4965070 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 85.0 7.28e-01 100.0% 80.0%
10268 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.90 85.0 6.85e-01 100.0% 75.2%
3232633 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.89 85.0 7.12e-01 100.0% 81.1%
4021830 7501.1.1.0 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.89 85.0 6.63e-01 100.0% 81.7%
2831687 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.89 85.0 7.29e-01 100.0% 76.3%
4295510 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.89 85.0 7.48e-01 100.0% 85.0%
3611921 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.88 84.0 6.52e-01 100.0% 77.8%
5015705 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.88 84.0 6.52e-01 100.0% 84.8%
4992215 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.88 84.0 6.65e-01 100.0% 86.5%
5009586 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.88 84.0 6.69e-01 100.0% 87.6%
4816241 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.88 77.0 6.64e-01 92.3% 98.9%
4946280 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.88 84.0 6.58e-01 100.0% 88.2%
2847460 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.88 83.0 7.43e-01 100.0% 80.8%
10273 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.87 83.0 6.76e-01 100.0% 89.4%
5030442 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.87 83.0 7.15e-01 100.0% 87.1%
4123104 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.87 83.0 7.21e-01 100.0% 84.8%
163852 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.87 82.0 6.23e-01 100.0% 82.7%
5063695 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.87 82.0 6.80e-01 100.0% 86.8%
3953555 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.86 81.0 6.78e-01 100.0% 86.8%
3289265 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.86 80.0 6.82e-01 100.0% 86.7%
163314 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.85 80.0 6.32e-01 100.0% 86.8%
1764169 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.84 79.0 6.06e-01 100.0% 78.9%
3289701 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.84 79.0 6.34e-01 100.0% 88.3%
3010946 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.83 77.0 6.64e-01 100.0% 86.9%
3581890 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.82 78.0 6.43e-01 100.0% 82.6%
3282759 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.82 77.0 6.49e-01 100.0% 87.4%
3284365 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.82 77.0 6.37e-01 100.0% 87.0%
4015428 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.82 76.0 6.80e-01 100.0% 98.8%
3278543 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.80 74.0 6.22e-01 100.0% 87.4%
3385448 7501.1.1.0 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.78 74.0 6.54e-01 100.0% 86.3%
3839944 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.78 73.0 6.22e-01 100.0% 82.1%
3740375 7501.1.1.0 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.70 65.0 5.41e-01 100.0% 77.3%
4200076 7550.1.1.0 a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain 0.66 50.0 5.48e-01 85.5% 98.9%
4180794 7550.1.1.1 a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › TP_methylase 0.64 51.0 5.29e-01 95.7% 91.8%
3958059 7550.1.1.0 a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain 0.64 51.0 5.49e-01 87.2% 100.0%
4949229 7550.1.1.5 a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › DUF7839 0.63 51.0 5.41e-01 88.9% 98.1%
3952784 7550.1.1.1 a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › TP_methylase 0.63 51.0 5.42e-01 87.2% 100.0%
4989709 7550.1.1.1 a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › TP_methylase 0.63 50.0 5.39e-01 85.5% 100.0%
4989175 7550.1.1.1 a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › TP_methylase 0.62 49.0 5.22e-01 96.6% 99.0%
4972542 7537.1.1.1 a/b three-layered sandwiches › PTS IIb component › PTS IIb component › PTS IIb component › PTSIIB_sorb 0.61 55.0 4.96e-01 100.0% 82.5%
3589061 7537.1.1.1 a/b three-layered sandwiches › PTS IIb component › PTS IIb component › PTS IIb component › PTSIIB_sorb 0.61 54.0 4.89e-01 100.0% 83.5%
3989685 7537.1.1.1 a/b three-layered sandwiches › PTS IIb component › PTS IIb component › PTS IIb component › PTSIIB_sorb 0.61 54.0 4.97e-01 100.0% 85.8%
5009530 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.61 48.0 3.80e-01 85.5% 92.8%
5021540 7550.1.1.0 a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain 0.60 48.0 5.15e-01 98.3% 100.0%
3279235 2003.1.4.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M 0.59 47.0 4.20e-01 87.2% 73.1%
3945569 7537.1.1.1 a/b three-layered sandwiches › PTS IIb component › PTS IIb component › PTS IIb component › PTSIIB_sorb 0.59 53.0 4.87e-01 100.0% 85.2%
4947304 7515.1.1.0 a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like 0.59 50.0 4.00e-01 91.5% 74.1%
3978457 7537.1.1.1 a/b three-layered sandwiches › PTS IIb component › PTS IIb component › PTS IIb component › PTSIIB_sorb 0.59 52.0 4.76e-01 100.0% 82.5%
4981671 7570.1.1.5 a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › PF31156 0.57 44.0 4.32e-01 81.2% 92.0%
4935979 2004.1.1.90 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CobA_CobO_BtuR 0.56 48.0 4.23e-01 94.0% 93.7%
3778862 2004.1.1.130 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NACHT 0.56 42.0 3.55e-01 80.3% 86.7%
3604469 7515.1.1.14 a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Metalloenzyme, PhosphMutase 0.56 50.0 3.84e-01 99.1% 80.7%
3503467 7512.1.1.1 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT 0.56 48.0 3.25e-01 94.0% 74.8%
3257794 7515.1.1.0 a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like 0.55 48.0 3.76e-01 100.0% 88.0%
4941012 2004.1.1.42 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.55 48.0 3.19e-01 99.1% 33.8%
4286526 7570.1.1.1 a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C 0.55 41.0 3.99e-01 80.3% 90.4%
5045845 7570.1.1.1 a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C 0.54 41.0 3.86e-01 82.1% 91.3%
2842011 7570.1.1.1 a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C 0.53 41.0 3.78e-01 82.1% 87.5%
3744287 7515.1.1.0 a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like 0.51 45.0 3.57e-01 100.0% 85.6%
3670890 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.51 40.0 3.87e-01 87.2% 99.3%