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MZ666938.1__UAJ16913.1__CPT_ProddE_033__00042
Bact-VirMZ666938.1__UAJ16913.1__CPT_ProddE_033__00042
Identity
- Accession:
- MZ666938 ↗
- Kingdom:
- phage
Quality
73.8
mean pLDDT
Taxonomy
Heunggongvirae›
Uroviricota›
Caudoviricetes›
Autographivirales›
Proddevirus›
Desulfovibrio_phage_ProddE
TaxID: 2866661
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 223-312
Domain cluster:
representative
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4fcyA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.71 | 41.0 | 4.42e-01 | 72.2% | 66.7% |
| 4v3iA00 | 1.25.40.590 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU | 0.70 | 57.0 | 4.78e-01 | 98.9% | 51.6% |
| 3besR03 | 6.10.140.1480 | Special › Helix non-globular › Helix Hairpins › | 0.69 | 40.0 | 4.83e-01 | 75.6% | 91.1% |
| 2yvkA01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.68 | 58.0 | 4.96e-01 | 95.6% | 60.8% |
| 2np5D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 55.0 | 4.64e-01 | 94.4% | 94.3% |
| 3lynB00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.65 | 45.0 | 4.01e-01 | 71.1% | 93.5% |
| 3himA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 54.0 | 4.28e-01 | 93.3% | 95.8% |
| 3fhnA03 | 1.10.357.100 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Dsl1p vesicle tethering complex, Tip20p subunit, domain C | 0.63 | 54.0 | 4.42e-01 | 96.7% | 85.1% |
| 2np3A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 53.0 | 4.58e-01 | 95.6% | 68.3% |
| 2v6eA01 | 1.10.287.3180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 45.0 | 4.90e-01 | 78.9% | 100.0% |
| 2pbxA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 49.0 | 3.84e-01 | 88.9% | 78.2% |
| 4g1tA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 36.0 | 4.22e-01 | 98.9% | 88.5% |
| 1zcdA00 | 1.20.1530.10 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › Na+/H+ antiporter like domain | 0.58 | 51.0 | 3.42e-01 | 100.0% | 73.7% |
| 3b0pA02 | 1.20.120.1460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 41.0 | 4.37e-01 | 86.7% | 86.7% |
| 5z7qA00 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.57 | 41.0 | 3.37e-01 | 76.7% | 63.1% |
| 3h20A04 | 1.10.1240.50 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › | 0.54 | 42.0 | 4.28e-01 | 92.2% | 88.8% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 39.0 | 3.65e-01 | 76.7% | 80.0% |
| 3ubcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 41.0 | 3.72e-01 | 95.6% | 63.4% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 37.0 | 3.40e-01 | 80.0% | 70.6% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3925909 | 371.1.1.0 ↗ | few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 | 0.72 | 50.0 | 4.82e-01 | 71.1% | 70.0% |
| 3928667 | 3277.2.1.1 ↗ | alpha arrays › Thymine dioxygenase JBP1 DNA-binding domain-like › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › CHD1-like_C | 0.72 | 58.0 | 5.73e-01 | 86.7% | 82.1% |
| 4997587 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.70 | 61.0 | 5.31e-01 | 95.6% | 68.1% |
| 5031466 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.68 | 58.0 | 5.31e-01 | 100.0% | 71.3% |
| 4945181 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.68 | 58.0 | 5.15e-01 | 95.6% | 68.5% |
| 3940560 | 371.1.1.0 ↗ | few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 | 0.67 | 47.0 | 4.49e-01 | 81.1% | 61.9% |
| 3534645 | 627.1.1.6 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › RIN1 | 0.66 | 47.0 | 4.66e-01 | 74.4% | 100.0% |
| 3385836 | 601.1.1.138 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF4118 | 0.66 | 56.0 | 5.30e-01 | 93.3% | 76.4% |
| 3586327 | 101.1.8.5 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topo_C_assoc | 0.65 | 48.0 | 4.71e-01 | 80.0% | 80.0% |
| 3509501 | 109.4.1.17 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin | 0.64 | 56.0 | 3.77e-01 | 98.9% | 36.4% |
| 5067071 | 604.17.1.0 ↗ | alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like | 0.63 | 39.0 | 4.54e-01 | 82.2% | 87.7% |
| 5002351 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.62 | 50.0 | 3.33e-01 | 87.8% | 75.7% |
| 3579325 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 40.0 | 3.82e-01 | 90.0% | 57.1% |
| 3255571 | 109.4.1.27 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › W2 | 0.60 | 51.0 | 4.16e-01 | 100.0% | 48.9% |
| 3590947 | 1141.1.1.0 ↗ | alpha arrays › Glycosyl transferase TarS linker domain › Glycosyl transferase TarS linker domain › Glycosyl transferase TarS linker domain | 0.58 | 51.0 | 4.85e-01 | 100.0% | 80.9% |
| 3427848 | 109.7.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E | 0.57 | 46.0 | 4.62e-01 | 98.9% | 88.8% |
| 3530376 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 42.0 | 4.15e-01 | 80.0% | 95.8% |
| 3311170 | 208.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded left-handed beta-helix › Trimeric LpxA-like enzymes › Trimeric LpxA-like enzymes | 0.55 | 41.0 | 3.16e-01 | 80.0% | 39.0% |
| 3740779 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.54 | 39.0 | 4.21e-01 | 95.6% | 90.7% |
| 3605439 | 192.4.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) | 0.54 | 39.0 | 4.26e-01 | 81.1% | 97.1% |
| 3974601 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.54 | 41.0 | 3.84e-01 | 81.1% | 66.4% |
| 3823532 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.53 | 40.0 | 3.46e-01 | 81.1% | 68.3% |
| 3938318 | 4992.1.1.0 ↗ | extended segments › RelB-like › RelB-like › RelB-like | 0.53 | 40.0 | 3.66e-01 | 81.1% | 83.3% |
| 3620592 | 6155.1.1.15 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF846 | 0.52 | 44.0 | 3.91e-01 | 100.0% | 87.9% |
| 3822132 | 109.4.1.494 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Npa1 | 0.52 | 45.0 | 3.62e-01 | 100.0% | 64.3% |
D2
medium
residues 46-134
D3
medium
residues 135-222
Domain cluster:
representative
CATH (40)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.77 | 57.0 | 5.75e-01 | 86.4% | 77.0% |
| 7m2wE01 | 1.20.120.1900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain | 0.73 | 53.0 | 3.58e-01 | 96.6% | 21.3% |
| 4i0xG00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.73 | 47.0 | 5.24e-01 | 75.0% | 83.8% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.72 | 53.0 | 5.59e-01 | 78.4% | 87.2% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.72 | 53.0 | 5.22e-01 | 95.5% | 72.3% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.70 | 62.0 | 5.78e-01 | 98.9% | 96.4% |
| 3ezhA00 | 1.20.120.960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain | 0.69 | 50.0 | 4.62e-01 | 76.1% | 100.0% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.69 | 48.0 | 4.22e-01 | 86.4% | 48.1% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.69 | 53.0 | 4.02e-01 | 83.0% | 67.3% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 50.0 | 3.66e-01 | 94.3% | 29.3% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.68 | 43.0 | 4.53e-01 | 89.8% | 71.8% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.67 | 46.0 | 4.95e-01 | 71.6% | 85.1% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.66 | 45.0 | 4.24e-01 | 96.6% | 59.8% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 51.0 | 3.69e-01 | 86.4% | 29.3% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 42.0 | 4.97e-01 | 79.5% | 93.5% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.65 | 42.0 | 4.68e-01 | 81.8% | 81.7% |
| 3tixA02 | 6.10.140.1690 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 51.0 | 5.30e-01 | 84.1% | 96.2% |
| 4gzrB00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 46.0 | 4.86e-01 | 86.4% | 85.7% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.64 | 45.0 | 4.89e-01 | 79.5% | 86.7% |
| 6cgaC02 | 1.20.58.860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 48.0 | 5.08e-01 | 89.8% | 89.7% |
| 1lvlA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.63 | 46.0 | 3.44e-01 | 77.3% | 33.2% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 43.0 | 3.93e-01 | 97.7% | 52.5% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 49.0 | 5.14e-01 | 88.6% | 90.1% |
| 1x3kA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.62 | 48.0 | 3.97e-01 | 80.7% | 52.4% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 45.0 | 4.51e-01 | 83.0% | 73.3% |
| 1ulyA02 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.62 | 43.0 | 4.09e-01 | 77.3% | 62.4% |
| 2az0B00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.62 | 45.0 | 4.90e-01 | 80.7% | 94.4% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 50.0 | 4.70e-01 | 89.8% | 88.0% |
| 2gxaE01 | 1.10.10.510 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain | 0.58 | 41.0 | 4.47e-01 | 85.2% | 89.0% |
| 1wteB01 | 1.10.3250.10 | Mainly Alpha › Orthogonal Bundle › type ii restriction endonuclease, domain 1 › type ii restriction endonuclease, domain 1 | 0.58 | 50.0 | 4.23e-01 | 95.5% | 78.9% |
| 5xdcB01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.58 | 42.0 | 3.92e-01 | 76.1% | 60.4% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.58 | 43.0 | 4.20e-01 | 80.7% | 70.7% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.57 | 38.0 | 3.93e-01 | 73.9% | 72.0% |
| 3v1vA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.56 | 49.0 | 3.31e-01 | 94.3% | 36.3% |
| 1n1cA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.55 | 44.0 | 4.57e-01 | 90.9% | 92.7% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 47.0 | 4.60e-01 | 95.5% | 100.0% |
| 4fqgB03 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.53 | 38.0 | 4.24e-01 | 79.5% | 100.0% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.53 | 42.0 | 4.23e-01 | 87.5% | 87.9% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.53 | 39.0 | 3.59e-01 | 80.7% | 62.9% |
| 3pvuA02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.52 | 37.0 | 3.88e-01 | 77.3% | 81.2% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4027540 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.77 | 60.0 | 4.86e-01 | 83.0% | 45.6% |
| 4575614 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.76 | 59.0 | 4.16e-01 | 81.8% | 56.2% |
| 4646569 | 4994.1.1.1 ↗ | alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 | 0.76 | 65.0 | 6.33e-01 | 92.0% | 87.4% |
| 4946275 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.76 | 58.0 | 4.03e-01 | 100.0% | 26.9% |
| 3620725 | 5041.1.1.17 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › Periphilin_C | 0.75 | 58.0 | 5.52e-01 | 83.0% | 73.3% |
| 4964983 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.72 | 53.0 | 5.32e-01 | 80.7% | 75.6% |
| 3776400 | 192.5.1.1 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 | 0.67 | 43.0 | 4.50e-01 | 87.5% | 71.2% |
| 4142346 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.67 | 50.0 | 4.68e-01 | 98.9% | 63.6% |
| 3258488 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 53.0 | 5.10e-01 | 86.4% | 94.0% |
| 4941252 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.66 | 45.0 | 5.04e-01 | 73.9% | 95.4% |
| 4140504 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.64 | 44.0 | 4.37e-01 | 71.6% | 77.9% |
| 3968965 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.64 | 51.0 | 5.06e-01 | 90.9% | 82.2% |
| 3732045 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.61 | 56.0 | 3.99e-01 | 100.0% | 44.7% |
| 3783692 | 632.2.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains | 0.61 | 54.0 | 4.49e-01 | 95.5% | 81.3% |
| 3935107 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.60 | 49.0 | 4.53e-01 | 86.4% | 88.2% |
| 3237980 | 2003.1.2.18 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.59 | 52.0 | 3.19e-01 | 100.0% | 68.7% |
| 3544536 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 49.0 | 4.63e-01 | 90.9% | 100.0% |
| 4295514 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.57 | 47.0 | 4.44e-01 | 87.5% | 80.0% |
| 3792508 | 632.7.1.35 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › TB2_DP1_HVA22 | 0.57 | 40.0 | 4.02e-01 | 78.4% | 72.2% |
| 3609435 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.57 | 45.0 | 4.47e-01 | 85.2% | 85.6% |
| 3229095 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.56 | 47.0 | 4.51e-01 | 90.9% | 83.0% |
| 3262083 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 49.0 | 4.64e-01 | 100.0% | 99.0% |
D4
medium
residues 377-452
Domain cluster:
representative
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6zhiB02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.62 | 42.0 | 4.13e-01 | 71.1% | 94.0% |
| 4rg9B04 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 41.0 | 3.83e-01 | 75.0% | 57.3% |
| 4qndA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.56 | 42.0 | 3.93e-01 | 81.6% | 84.5% |
| 4u2vA02 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.56 | 47.0 | 4.63e-01 | 93.4% | 100.0% |
| 2vklA00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.55 | 42.0 | 4.24e-01 | 84.2% | 97.4% |
| 1e3mB04 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.54 | 37.0 | 3.00e-01 | 72.4% | 65.1% |
| 2hjmA01 | 1.20.120.460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like | 0.52 | 35.0 | 3.46e-01 | 71.1% | 82.6% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5030291 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.72 | 56.0 | 4.94e-01 | 82.9% | 91.7% |
| 4011171 | 192.15.1.126 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF7607 | 0.65 | 53.0 | 4.61e-01 | 89.5% | 95.7% |
| 3205299 | 226.1.1.0 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain | 0.52 | 38.0 | 2.99e-01 | 80.3% | 63.8% |
| 4404513 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.52 | 40.0 | 4.10e-01 | 90.8% | 92.0% |
D5
medium
residues 453-549
Domain cluster:
representative
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2bskE00 | 1.10.287.810 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains | 0.81 | 44.0 | 5.35e-01 | 73.2% | 82.5% |
| 3kb9A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.69 | 46.0 | 3.12e-01 | 96.9% | 19.4% |
| 3lphC00 | 6.10.140.630 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 36.0 | 4.47e-01 | 74.2% | 86.2% |
| 5fmgG00 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.65 | 51.0 | 3.88e-01 | 82.5% | 46.6% |
| 2a2fX01 | 1.10.357.30 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Exocyst complex subunit Sec15 C-terminal domain, N-terminal subdomain | 0.65 | 45.0 | 3.76e-01 | 74.2% | 41.9% |
| 3vkgA11 | 1.20.920.20 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.64 | 45.0 | 4.32e-01 | 72.2% | 85.5% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.63 | 38.0 | 4.12e-01 | 74.2% | 70.7% |
| 4xt1A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 58.0 | 4.07e-01 | 100.0% | 35.7% |
| 4xxiA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.63 | 43.0 | 3.79e-01 | 71.1% | 60.5% |
| 1cpcA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.62 | 43.0 | 3.59e-01 | 70.1% | 64.2% |
| 8itfR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 54.0 | 3.87e-01 | 99.0% | 42.1% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 42.0 | 4.19e-01 | 73.2% | 75.5% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.60 | 43.0 | 3.83e-01 | 75.3% | 87.9% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 46.0 | 4.08e-01 | 93.8% | 58.2% |
| 4ys0A02 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.59 | 54.0 | 4.45e-01 | 100.0% | 98.2% |
| 3hd6A00 | 1.10.3430.10 | Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains | 0.59 | 53.0 | 3.51e-01 | 100.0% | 67.2% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.59 | 40.0 | 3.99e-01 | 70.1% | 88.3% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.59 | 41.0 | 4.28e-01 | 72.2% | 82.2% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 42.0 | 3.14e-01 | 74.2% | 31.6% |
| 2hwjA02 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.58 | 36.0 | 4.24e-01 | 96.9% | 100.0% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 49.0 | 4.18e-01 | 93.8% | 58.7% |
| 4al0A00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.57 | 49.0 | 4.32e-01 | 94.8% | 76.7% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.57 | 49.0 | 4.29e-01 | 93.8% | 64.4% |
| 4wpcA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 47.0 | 3.34e-01 | 87.6% | 67.8% |
| 4didB01 | 1.20.58.450 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cell division control protein 42 homolog | 0.57 | 40.0 | 3.77e-01 | 100.0% | 61.4% |
| 6j8eA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.57 | 40.0 | 3.88e-01 | 72.2% | 98.1% |
| 6lumG01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.57 | 49.0 | 4.65e-01 | 93.8% | 85.7% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 40.0 | 3.39e-01 | 74.2% | 83.9% |
| 3lynB00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.56 | 48.0 | 4.47e-01 | 100.0% | 75.0% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 45.0 | 3.85e-01 | 89.7% | 54.6% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 48.0 | 4.14e-01 | 93.8% | 84.6% |
| 7sf7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 48.0 | 3.59e-01 | 100.0% | 43.9% |
| 3ez0C00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 50.0 | 3.89e-01 | 100.0% | 96.2% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 40.0 | 3.74e-01 | 76.3% | 71.7% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.55 | 40.0 | 3.41e-01 | 76.3% | 92.5% |
| 1by1A00 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.55 | 38.0 | 2.99e-01 | 71.1% | 75.1% |
| 3buxB01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.55 | 45.0 | 4.12e-01 | 89.7% | 70.5% |
| 4iu9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.55 | 45.0 | 3.57e-01 | 89.7% | 83.7% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 47.0 | 3.72e-01 | 93.8% | 64.0% |
| 2yjkC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 48.0 | 4.06e-01 | 96.9% | 80.9% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 45.0 | 4.06e-01 | 90.7% | 68.4% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.53 | 42.0 | 3.82e-01 | 99.0% | 63.1% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 41.0 | 3.90e-01 | 91.8% | 69.5% |
| 2xl4A00 | 1.20.120.1420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain | 0.53 | 43.0 | 3.73e-01 | 97.9% | 57.8% |
| 3q9oA02 | 3.90.1350.10 | Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain | 0.52 | 45.0 | 3.80e-01 | 95.9% | 92.8% |
| 1t11A02 | 1.10.3120.10 | Mainly Alpha › Orthogonal Bundle › Trigger factor, domain 2 › Trigger factor, C-terminal domain | 0.52 | 43.0 | 3.68e-01 | 91.8% | 75.3% |
| 1dbhA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.52 | 43.0 | 3.39e-01 | 96.9% | 41.7% |
| 4akfA01 | 3.40.1090.10 | Alpha Beta › 3-Layer(aba) Sandwich › Cytosolic phospholipase A2 catalytic domain › Cytosolic phospholipase A2 catalytic domain | 0.52 | 43.0 | 3.10e-01 | 97.9% | 92.2% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 44.0 | 3.81e-01 | 97.9% | 87.3% |
| 7px0A01 | 3.30.365.10 | Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain | 0.51 | 41.0 | 3.83e-01 | 88.7% | 89.2% |
ECOD (51)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3804317 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.70 | 58.0 | 5.56e-01 | 97.9% | 77.0% |
| 3976839 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.69 | 61.0 | 6.05e-01 | 100.0% | 92.0% |
| 3216411 | 4009.1.1.23 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › C_tripleX | 0.66 | 53.0 | 5.63e-01 | 93.8% | 98.8% |
| 3244841 | 5001.1.1.16 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srt | 0.65 | 59.0 | 4.07e-01 | 99.0% | 36.8% |
| 3394799 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.64 | 48.0 | 3.41e-01 | 79.4% | 53.3% |
| 3389029 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 38.0 | 3.58e-01 | 75.3% | 50.4% |
| 3435434 | 632.1.1.13 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N | 0.62 | 47.0 | 4.62e-01 | 91.8% | 73.3% |
| 4959229 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.62 | 55.0 | 4.40e-01 | 97.9% | 92.1% |
| 5000698 | 604.38.1.0 ↗ | alpha bundles › Spectrin repeat-like › Legionella effector SdeA 3-helical bundle › Legionella effector SdeA 3-helical bundle | 0.61 | 42.0 | 4.09e-01 | 75.3% | 64.8% |
| 4371240 | 632.7.1.55 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › DUF2605 | 0.61 | 43.0 | 4.40e-01 | 89.7% | 74.7% |
| 3193381 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.60 | 54.0 | 3.93e-01 | 97.9% | 93.7% |
| 5044317 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.59 | 49.0 | 3.66e-01 | 90.7% | 41.5% |
| 3182625 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.59 | 42.0 | 3.26e-01 | 73.2% | 97.1% |
| 3464325 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.59 | 44.0 | 4.72e-01 | 95.9% | 90.6% |
| 3660383 | 1075.1.2.12 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › EMP70 | 0.59 | 44.0 | 3.54e-01 | 78.4% | 71.9% |
| 3606080 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.59 | 40.0 | 3.88e-01 | 76.3% | 61.8% |
| 3259409 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.59 | 42.0 | 3.74e-01 | 75.3% | 90.0% |
| 3605990 | 5054.1.1.70 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Yip1 | 0.59 | 52.0 | 4.18e-01 | 99.0% | 96.3% |
| 3206514 | 192.2.1.6 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_3 | 0.59 | 42.0 | 3.78e-01 | 74.2% | 78.5% |
| 3387160 | 3755.1.1.8 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › FliJ | 0.58 | 41.0 | 3.57e-01 | 72.2% | 51.4% |
| 3400926 | 3758.1.1.45 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › Not3 | 0.58 | 49.0 | 4.67e-01 | 95.9% | 77.4% |
| 3248839 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.57 | 50.0 | 4.70e-01 | 100.0% | 79.2% |
| 3612019 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 43.0 | 4.49e-01 | 93.8% | 85.6% |
| 3721451 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.57 | 45.0 | 3.70e-01 | 94.8% | 47.6% |
| 3324034 | 1015.1.1.7 ↗ | alpha complex topology › Insulin-induced gene (Insig) homologs › Insulin-induced gene (Insig) homologs › Insulin-induced gene (Insig) homologs › Yip1 | 0.57 | 51.0 | 4.28e-01 | 100.0% | 97.6% |
| 5075503 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.57 | 45.0 | 4.17e-01 | 92.8% | 67.5% |
| 5059356 | 159.1.2.0 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related | 0.56 | 50.0 | 4.74e-01 | 100.0% | 88.1% |
| 4199161 | 3896.1.1.3 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase › CobS | 0.56 | 50.0 | 3.73e-01 | 99.0% | 42.7% |
| 3491873 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.56 | 47.0 | 4.78e-01 | 89.7% | 94.7% |
| 3471803 | 5038.2.1.1 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG | 0.56 | 48.0 | 4.42e-01 | 93.8% | 78.4% |
| 3655748 | 601.1.2.118 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › CASP_dom | 0.56 | 48.0 | 4.17e-01 | 100.0% | 61.5% |
| 3800517 | 3937.1.1.9 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Piezo_THU9_anchor | 0.56 | 39.0 | 3.34e-01 | 72.2% | 96.0% |
| 3615244 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 41.0 | 3.51e-01 | 79.4% | 49.4% |
| 3279896 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.55 | 49.0 | 4.02e-01 | 100.0% | 94.4% |
| 4027655 | 5069.1.3.23 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DAD | 0.55 | 47.0 | 4.70e-01 | 100.0% | 92.0% |
| 3220742 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.55 | 47.0 | 3.86e-01 | 92.8% | 66.3% |
| 3448189 | 3755.4.1.17 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N | 0.55 | 47.0 | 3.94e-01 | 93.8% | 75.2% |
| 4838076 | 2007.1.19.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › FabD/lysophospholipase-like › Acyl_transf_1 | 0.54 | 48.0 | 4.69e-01 | 100.0% | 89.8% |
| 5059804 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.54 | 39.0 | 3.80e-01 | 90.7% | 68.6% |
| 3713666 | 601.1.2.90 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Not3 | 0.54 | 47.0 | 4.50e-01 | 95.9% | 83.5% |
| 3805085 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.54 | 45.0 | 3.88e-01 | 90.7% | 64.5% |
| 3508496 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 48.0 | 3.70e-01 | 100.0% | 49.8% |
| 3593724 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 36.0 | 3.36e-01 | 76.3% | 55.2% |
| 3731064 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.53 | 44.0 | 4.21e-01 | 91.8% | 80.0% |
| 3382610 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.52 | 44.0 | 3.19e-01 | 90.7% | 65.9% |
| 3589439 | 1179.1.1.1 ↗ | alpha complex topology › TelC toxin domain › TelC toxin domain › TelC toxin domain › YkzU | 0.52 | 47.0 | 3.40e-01 | 99.0% | 61.1% |
| 3410594 | 4177.1.1.6 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg | 0.52 | 44.0 | 3.45e-01 | 91.8% | 81.0% |
| 3789005 | 150.1.1.114 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PF30036 | 0.52 | 43.0 | 3.58e-01 | 95.9% | 50.3% |
| 3248022 | 601.1.2.80 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Yip1 | 0.52 | 44.0 | 3.64e-01 | 94.8% | 84.4% |
| 3229124 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.52 | 36.0 | 3.20e-01 | 73.2% | 78.6% |
| 3400028 | 3843.1.1.30 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF4781 | 0.51 | 41.0 | 4.38e-01 | 94.8% | 100.0% |
D6
medium
residues 596-646
Domain cluster:
representative
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2lpeA02 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.61 | 43.0 | 3.94e-01 | 74.5% | 67.6% |
| 1llaA03 | 1.10.1280.10 | Mainly Alpha › Orthogonal Bundle › di-copper center containing domain from catechol oxidase › Di-copper center containing domain from catechol oxidase | 0.60 | 45.0 | 2.99e-01 | 88.2% | 58.9% |
| 2keoA00 | 3.10.120.10 | Alpha Beta › Roll › Flavocytochrome B2; Chain A, domain 1 › Cytochrome b5-like heme/steroid binding domain | 0.60 | 46.0 | 3.95e-01 | 90.2% | 50.0% |
| 4m0mA03 | 1.20.1270.430 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 42.0 | 3.83e-01 | 82.4% | 93.7% |
| 3nbiA01 | 1.10.8.1020 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain | 0.56 | 38.0 | 3.70e-01 | 70.6% | 91.4% |
| 2x1dA02 | 1.10.10.2120 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.56 | 50.0 | 4.33e-01 | 96.1% | 67.6% |
| 1uj8A00 | 1.10.10.600 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › IscX-like | 0.53 | 40.0 | 3.63e-01 | 84.3% | 67.1% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5054534 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.67 | 54.0 | 4.31e-01 | 92.2% | 50.5% |
| 3596754 | 101.7.1.0 ↗ | alpha arrays › HTH › DEK-C › DEK-C | 0.65 | 42.0 | 3.99e-01 | 100.0% | 53.8% |
| 4951714 | 131.1.1.0 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like | 0.63 | 53.0 | 3.20e-01 | 100.0% | 71.3% |
| 3809782 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.59 | 43.0 | 4.00e-01 | 84.3% | 72.9% |