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M_polyprotein

Euk-Vir

Bunyamwera_virus

M_polyprotein__NP_047212__Bunyamwera_virus__35304

Identity

Accession:: NP_047212 ↗
Protein ID:: M_polyprotein
Kingdom:: euk

Quality

77.1 mean pLDDT

Taxonomy

Orthornavirae› Negarnaviricota› Bunyaviricetes› Elliovirales› Peribunyaviridae› Orthobunyavirus› Bunyamwera_virus

TaxID: 35304

Cluster

View cluster (42 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 114-185

PDB

Domain cluster: rep: polyprotein__YP_009667022__Witwatersrand_virus__1678231__D115-177

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03563.19 best	Bunya_G2	111.3	7.30e-32	100.0%	25.6%

D2 high residues 728-821

PDB

Domain cluster: rep: polyprotein__YP_009117085__Maprik_virus__1590836__D700-782

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03557.22 best	Bunya_G1	68.5	5.60e-19	100.0%	10.5%

D3 high residues 831-903

PDB

Domain cluster: rep: polyprotein__YP_008709777__Murrumbidgee_virus__1406134__D787-850

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03557.22 best	Bunya_G1	67.9	8.60e-19	100.0%	8.3%

D4 medium residues 29-111

PDB

Domain cluster: rep: Glycoprotein_precursor__YP_010086209__Caimito_virus__2572766__D29-112

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03563.19 best	Bunya_G2	83.3	2.40e-23	100.0%	29.2%

D5 medium residues 379-472

PDB

D6 medium residues 473-570

PDB

Domain cluster: rep: polyprotein__YP_010084299__California_encephalitis_virus__35305__D489-574

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03557.22 best	Bunya_G1	31.0	1.20e-07	63.3%	6.6%

CATH (7)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2zopA00	1.10.520.30	Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain	0.58	40.0	3.84e-01	70.4%	71.4%
1tj7A01	1.10.275.10	Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain)	0.57	39.0	3.89e-01	71.4%	100.0%
4i8oA03	1.10.8.1130	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Bacterial toxin RNase RnlA/LsoA, C-terminal Dmd-binding domain	0.53	31.0	3.72e-01	100.0%	86.6%
3qvmB00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.52	40.0	2.94e-01	82.7%	85.7%
3k7dA03	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.51	39.0	3.53e-01	80.6%	97.8%
1vb5A01	1.20.120.420	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1	0.51	38.0	3.88e-01	79.6%	96.8%
1oohA00	1.10.238.20	Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain	0.50	38.0	3.58e-01	82.7%	88.9%

ECOD (14)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2504455	7069.1.1.1 ↗	alpha complex topology › Head domain of SBV glycoprotein Gc › Head domain of SBV glycoprotein Gc › Head domain of SBV glycoprotein Gc › Bunya_G1	0.94	87.0	6.20e-01	94.9%	38.7%
2504456	7069.1.1.1 ↗	alpha complex topology › Head domain of SBV glycoprotein Gc › Head domain of SBV glycoprotein Gc › Head domain of SBV glycoprotein Gc › Bunya_G1	0.91	84.0	6.06e-01	96.9%	39.8%
5009729	1030.1.1.0 ↗	alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2	0.57	39.0	3.73e-01	72.4%	60.0%
3684818	4952.1.1.1 ↗	alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › Lyase_1	0.55	40.0	3.79e-01	76.5%	94.8%
3365581	4952.1.1.1 ↗	alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › Lyase_1	0.54	38.0	3.62e-01	72.4%	91.3%
4073103	4952.1.1.1 ↗	alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › Lyase_1	0.54	38.0	3.62e-01	72.4%	91.3%
4290275	4952.1.1.1 ↗	alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › Lyase_1	0.54	38.0	3.71e-01	74.5%	95.5%
4291782	4952.1.1.0 ↗	alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like	0.53	37.0	3.64e-01	72.4%	95.5%
4114241	4952.1.1.0 ↗	alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like	0.52	36.0	3.64e-01	72.4%	98.0%
4947230	4952.1.1.1 ↗	alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › Lyase_1	0.52	38.0	3.73e-01	76.5%	99.0%
5039992	7579.1.1.44 ↗	a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_6	0.52	39.0	2.92e-01	81.6%	87.5%
4213337	4952.1.1.0 ↗	alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like	0.51	35.0	3.53e-01	71.4%	98.0%
3614072	2484.1.1.0 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like	0.51	39.0	3.10e-01	85.7%	84.8%
4125194	3455.1.1.0 ↗	alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors	0.50	36.0	3.91e-01	96.9%	98.7%

D7 medium residues 916-943_1236-1356

PDB

Domain cluster: rep: polyprotein__YP_009666886__Leanyer_virus__999729__D1233-1338

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03557.22 best	Bunya_G1	135.1	4.00e-39	82.5%	14.0%

D8 medium residues 1006-1020_1083-1097_1120-1175_1199-1235

PDB

Domain cluster: rep: polyprotein__YP_009667022__Witwatersrand_virus__1678231__D1007-1020_1078-1094_1129-1173_1199-1230

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03557.22 best	Bunya_G1	77.6	9.70e-22	54.5%	7.0%

D9 medium residues 1021-1082_1176-1198

PDB

Domain cluster: rep: glycoprotein_precursor__YP_009551599__Avalon_virus__1810950__D843-903_1047-1069

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03557.22 best	Bunya_G1	136.6	1.50e-39	74.1%	7.2%
PF03557.22	Bunya_G1	38.7	5.80e-10	28.2%	2.7%

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1t7vA02	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.62	40.0	3.93e-01	72.9%	61.1%
1fp5A01	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.62	40.0	3.86e-01	72.9%	57.0%
3m86A00	2.60.40.2020	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.56	39.0	3.60e-01	72.9%	70.3%
1k8kD01	3.30.1460.20	Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, ›	0.54	37.0	3.11e-01	70.6%	49.0%
3prbA01	3.10.50.40	Alpha Beta › Roll › Chitinase A; domain 3 ›	0.53	36.0	3.43e-01	70.6%	98.1%
3o4oB03	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.52	36.0	3.36e-01	71.8%	56.0%
4bfiB02	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.52	33.0	3.27e-01	70.6%	58.9%
1yewA01	2.60.120.570	Mainly Beta › Sandwich › Jelly Rolls › Particulate methane monooxygenase, b subunit. Chain: A, domain 1	0.52	36.0	3.06e-01	71.8%	65.8%

ECOD (15)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3503920	5090.1.1.8 ↗	beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › EFF-AFF	0.69	62.0	4.07e-01	100.0%	60.3%
3056811	5090.1.1.2 ↗	beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › Hanta_Gc_N	0.68	58.0	3.98e-01	96.5%	58.0%
4840163	11.1.1.28 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Alpha_E1_glycop	0.65	57.0	3.93e-01	97.6%	63.8%
3027089	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.61	36.0	3.64e-01	70.6%	56.3%
3883234	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.59	37.0	3.61e-01	71.8%	55.8%
3925038	11.1.1.179 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3	0.58	39.0	3.38e-01	70.6%	44.6%
3792375	11.1.1.179 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3	0.55	38.0	3.47e-01	71.8%	53.9%
3897613	11.1.1.653 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_Dlec1_1	0.55	38.0	3.64e-01	71.8%	85.0%
3398996	12.1.1.0 ↗	beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain	0.53	35.0	3.20e-01	70.6%	48.3%
3896079	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.52	29.0	3.11e-01	97.6%	61.3%
3560223	304.102.1.2 ↗	a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruD	0.52	35.0	2.65e-01	70.6%	76.9%
6693	244.1.1.0 ↗	a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C	0.51	44.0	3.54e-01	100.0%	97.2%
3533153	5.1.3.254 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › CATSPERB_Ig-like	0.51	35.0	3.22e-01	71.8%	53.0%
4927084	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.50	34.0	3.49e-01	70.6%	87.1%
3277295	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.50	34.0	3.32e-01	71.8%	80.0%

D10 medium residues 1357-1433

PDB