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Metal_dependent_phosphohydrolase
Euk-VirAcanthamoeba_polyphaga_moumouvirus
Metal_dependent_phosphohydrolase__YP_007354777__Acanthamoeba_polyphaga_moumouvirus__1269028
Identity
- Accession:
- YP_007354777 ↗
- Protein ID:
- Metal_dependent_phosphohydrolase
- Kingdom:
- euk
Quality
81.4
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Moumouvirus›
Acanthamoeba_polyphaga_moumouvirus
TaxID: 1269028
Cluster
View cluster (20 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-113
Domain cluster:
rep: MW302330.1__QTJ62991.1__X__00013__D3-108
CATH (32)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3djbA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.86 | 70.0 | 7.60e-01 | 100.0% | 100.0% |
| 2qgsB01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.85 | 64.0 | 7.17e-01 | 100.0% | 100.0% |
| 3u1nB01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.81 | 76.0 | 5.29e-01 | 99.1% | 51.2% |
| 2pq7A00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.78 | 67.0 | 5.77e-01 | 100.0% | 60.1% |
| 2q14B01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.70 | 64.0 | 4.99e-01 | 99.1% | 53.2% |
| 2pkeA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.67 | 44.0 | 5.06e-01 | 85.0% | 94.9% |
| 3vkgA09 | 1.20.920.30 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.67 | 60.0 | 5.53e-01 | 100.0% | 80.6% |
| 3h4cA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.66 | 49.0 | 5.27e-01 | 99.1% | 92.7% |
| 6z4xA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.64 | 45.0 | 4.06e-01 | 100.0% | 52.9% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.63 | 44.0 | 4.97e-01 | 80.5% | 100.0% |
| 7qocA01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.61 | 48.0 | 4.11e-01 | 100.0% | 51.9% |
| 3p5nA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.61 | 46.0 | 4.11e-01 | 82.3% | 63.1% |
| 2w9zA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.60 | 51.0 | 4.88e-01 | 100.0% | 79.7% |
| 4kk2B00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.59 | 45.0 | 3.29e-01 | 81.4% | 87.2% |
| 3wa8B00 | 1.10.520.40 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › CRISPR-associated protein Cse2 | 0.58 | 34.0 | 2.99e-01 | 85.0% | 36.6% |
| 1zcdA00 | 1.20.1530.10 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › Na+/H+ antiporter like domain | 0.57 | 50.0 | 3.55e-01 | 100.0% | 74.2% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.55 | 46.0 | 4.18e-01 | 91.2% | 98.1% |
| 5tprA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.55 | 48.0 | 3.86e-01 | 95.6% | 95.4% |
| 2py6A01 | 1.20.1270.160 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 35.0 | 4.12e-01 | 93.8% | 100.0% |
| 4zvaA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 48.0 | 4.41e-01 | 100.0% | 83.9% |
| 7uzqK01 | 1.10.3430.10 | Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains | 0.53 | 48.0 | 3.38e-01 | 100.0% | 33.9% |
| 2iw3A02 | 1.20.1390.20 | Mainly Alpha › Up-down Bundle › PWI domain › | 0.53 | 39.0 | 4.23e-01 | 82.3% | 96.7% |
| 4gx0A01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 34.0 | 3.59e-01 | 85.8% | 70.9% |
| 1un8A02 | 1.25.40.340 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain | 0.53 | 40.0 | 3.47e-01 | 82.3% | 95.3% |
| 1wgwA00 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.53 | 36.0 | 3.78e-01 | 99.1% | 78.8% |
| 1sqgA01 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.52 | 44.0 | 4.13e-01 | 95.6% | 86.5% |
| 2oebA00 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.51 | 43.0 | 3.98e-01 | 93.8% | 77.6% |
| 3cr3A00 | 1.25.40.340 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain | 0.51 | 40.0 | 3.44e-01 | 85.0% | 95.8% |
| 2lrmA00 | 1.10.890.30 | Mainly Alpha › Orthogonal Bundle › 10k-s Protein, Hypothetical Protein A; Chain A › YmgD protein | 0.50 | 30.0 | 3.29e-01 | 92.0% | 75.0% |
| 2gruA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.50 | 44.0 | 3.72e-01 | 98.2% | 99.0% |
| 1fouA01 | 1.10.246.30 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.50 | 30.0 | 3.48e-01 | 100.0% | 86.5% |
| 7jgsG02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 32.0 | 3.37e-01 | 85.0% | 72.4% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4953492 | 131.1.1.3 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD | 0.80 | 68.0 | 5.95e-01 | 93.8% | 63.9% |
| 3294130 | 5053.1.1.1 ↗ | alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC | 0.66 | 45.0 | 3.10e-01 | 84.1% | 20.0% |
| 3963163 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.63 | 50.0 | 4.57e-01 | 85.8% | 89.0% |
| 4223269 | 101.1.10.50 ↗ | alpha arrays › HTH › HTH › Cyclin-like › PF29928 | 0.63 | 56.0 | 5.01e-01 | 100.0% | 70.0% |
| 4030228 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.60 | 48.0 | 3.67e-01 | 85.8% | 64.6% |
| 4615076 | 377.1.1.11 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › RecO_C | 0.60 | 45.0 | 4.17e-01 | 80.5% | 98.0% |
| 4522412 | 131.2.1.7 ↗ | alpha complex topology › PDEase-like › Poly A polymerase C-terminal region-like › Poly A polymerase C-terminal region-like › HD | 0.59 | 52.0 | 4.01e-01 | 100.0% | 54.4% |
| 4085235 | 377.1.1.11 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › RecO_C | 0.59 | 47.0 | 4.24e-01 | 85.8% | 98.7% |
| 3959657 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.58 | 44.0 | 4.21e-01 | 80.5% | 92.3% |
| 5036896 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.57 | 46.0 | 3.65e-01 | 87.6% | 73.7% |
| 4965582 | 4953.2.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › Lid-like insertion of Propionyl-CoA synthase (PCS) ligase domain › Lid-like insertion of Propionyl-CoA synthase (PCS) ligase domain | 0.57 | 37.0 | 4.11e-01 | 78.8% | 83.3% |
| 3957111 | 225.1.1.6 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_2 | 0.56 | 42.0 | 4.01e-01 | 79.6% | 83.7% |
| 4152848 | 377.1.1.11 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › RecO_C | 0.56 | 44.0 | 4.03e-01 | 85.0% | 100.0% |
| 5017125 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.56 | 42.0 | 3.49e-01 | 79.6% | 49.5% |
| 4380981 | 377.1.1.11 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › RecO_C | 0.56 | 44.0 | 3.98e-01 | 85.0% | 95.5% |
| 3824988 | 109.3.1.339 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Vps35 | 0.55 | 39.0 | 3.39e-01 | 72.6% | 70.3% |
| 3878148 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.54 | 46.0 | 3.88e-01 | 94.7% | 61.0% |
| 3777646 | 101.1.10.13 ↗ | alpha arrays › HTH › HTH › Cyclin-like › DUF3452 | 0.54 | 45.0 | 4.07e-01 | 99.1% | 65.0% |
| 3660568 | 101.1.10.21 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N,Cyclin_C | 0.54 | 47.0 | 3.71e-01 | 100.0% | 90.4% |
| 3970612 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.53 | 36.0 | 3.44e-01 | 92.9% | 56.4% |
| 3370463 | 5069.1.1.49 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › TIC20 | 0.53 | 31.0 | 3.01e-01 | 85.8% | 50.4% |
| 3969457 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.53 | 41.0 | 3.85e-01 | 84.1% | 95.9% |
| 3622936 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.53 | 47.0 | 4.21e-01 | 100.0% | 84.4% |
| 3176026 | 610.2.1.0 ↗ | alpha arrays › ERP29 C domain-like › Helical domain of Sec23/24 › Helical domain of Sec23/24 | 0.53 | 36.0 | 3.64e-01 | 100.0% | 69.6% |
| 4598950 | 613.1.1.0 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 0.52 | 44.0 | 3.80e-01 | 94.7% | 61.1% |
| 4501767 | 1175.1.1.1 ↗ | alpha complex topology › Apolipoprotein N-acyltransferase transmembrane domain › Apolipoprotein N-acyltransferase transmembrane domain › Apolipoprotein N-acyltransferase transmembrane domain › LNT_N | 0.52 | 44.0 | 3.56e-01 | 97.3% | 78.8% |
| 3575711 | 109.4.1.543 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › efThoc1 | 0.52 | 38.0 | 3.36e-01 | 75.2% | 71.9% |
| 3619920 | 613.1.1.1 ↗ | alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c | 0.52 | 44.0 | 3.74e-01 | 97.3% | 60.5% |
| 5043647 | 1075.1.1.67 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › 12TM_1 | 0.51 | 42.0 | 3.49e-01 | 92.9% | 71.1% |
| 4309890 | 4002.1.1.4 ↗ | alpha bundles › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › DHQS_C | 0.51 | 46.0 | 3.93e-01 | 100.0% | 97.8% |
| 3587560 | 633.2.1.1 ↗ | alpha bundles › Bromodomain-like › Carnobacteriocin B2 immunity protein › Carnobacteriocin B2 immunity protein › EntA_Immun | 0.50 | 39.0 | 3.94e-01 | 100.0% | 83.5% |
D2
high
residues 127-236