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MutH_Vsr_archaeal_HJR-like_endonuclease

Euk-Vir

Brazilian_marseillevirus

MutH_Vsr_archaeal_HJR-like_endonuclease__YP_009238811__Brazilian_marseillevirus__1813599

Identity

Accession:
YP_009238811 ↗
Protein ID:
MutH_Vsr_archaeal_HJR-like_endonuclease
Kingdom:
euk

Quality

71.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 44-102
PDB
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3oymA02 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.65 47.0 4.50e-01 78.0% 81.4%
1v2dA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.63 53.0 4.15e-01 96.6% 61.9%
2yrrA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.63 54.0 4.47e-01 100.0% 82.0%
2z61A01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.62 52.0 3.87e-01 96.6% 52.8%
2mamA00 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.61 46.0 3.75e-01 83.1% 91.5%
2qrdA00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.61 53.0 4.34e-01 100.0% 78.1%
3t4nA01 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.61 53.0 4.58e-01 100.0% 77.1%
6cmzA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.60 42.0 3.34e-01 72.9% 80.7%
3b46A01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.59 50.0 3.73e-01 100.0% 64.5%
4emyA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.59 51.0 3.70e-01 100.0% 46.5%
4wh5A00 3.30.460.40 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.59 44.0 3.29e-01 83.1% 48.1%
2iiiA00 3.60.90.10 Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase 0.58 50.0 4.03e-01 98.3% 71.7%
4qnyA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.58 49.0 4.00e-01 98.3% 100.0%
2k5nA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.58 42.0 3.93e-01 78.0% 78.4%
2nyiA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.58 49.0 4.23e-01 93.2% 78.9%
6rjiA03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.58 37.0 3.94e-01 72.9% 75.0%
1svvB02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.57 47.0 4.15e-01 94.9% 88.0%
2qetA02 4.10.470.10 Few Secondary Structures › Irregular › Ricin (A Subunit), domain 2 › Ricin (A Subunit), domain 2 0.57 39.0 3.60e-01 72.9% 86.4%
2kfpA00 3.90.1150.30 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.57 49.0 3.92e-01 100.0% 96.0%
4zm3B01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.57 47.0 3.63e-01 94.9% 67.6%
3kbgA02 2.40.50.740 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Ribosomal protein S4, central domain 0.57 37.0 3.85e-01 79.7% 75.5%
3rheA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.56 38.0 3.21e-01 72.9% 37.7%
7nasX01 3.30.300.70 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › RimP-like superfamily, N-terminal 0.56 44.0 4.10e-01 89.8% 89.9%
2re3A02 2.30.270.10 Mainly Beta › Roll › duf1285 protein fold › duf1285 protein 0.56 40.0 3.84e-01 78.0% 80.0%
2rcnA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 40.0 3.99e-01 76.3% 80.3%
1zq1A01 2.30.30.520 Mainly Beta › Roll › SH3 type barrels. › 0.55 42.0 3.92e-01 86.4% 83.1%
4huzA01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.55 45.0 3.35e-01 93.2% 38.0%
4jpdA00 3.30.920.10 Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY 0.55 43.0 3.74e-01 96.6% 82.6%
1b9mA03 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.55 40.0 3.80e-01 79.7% 91.5%
2auwA01 3.30.2020.10 Alpha Beta › 2-Layer Sandwich › NE0471 N-terminal domain-like › NE0471-like N-terminal domain 0.54 36.0 3.35e-01 71.2% 92.7%
2bwnB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 44.0 3.34e-01 94.9% 54.7%
3ss3C02 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.54 45.0 2.90e-01 98.3% 24.1%
2uz8A01 3.40.30.90 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › 0.54 43.0 4.50e-01 94.9% 100.0%
2pm9A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.54 43.0 2.81e-01 93.2% 24.2%
3e82E02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.54 44.0 3.16e-01 98.3% 74.0%
3ol0B00 6.20.90.30 Special › Other non-globular › SH3 type barrels. › 0.54 30.0 3.51e-01 83.1% 78.0%
4fd0A01 2.60.40.3630 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 37.0 3.42e-01 72.9% 82.3%
4pavB00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.53 45.0 3.59e-01 100.0% 87.0%
4eutB02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.53 40.0 2.82e-01 83.1% 49.0%
6vh5C03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.53 44.0 3.87e-01 93.2% 74.2%
3oajA02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.53 39.0 3.13e-01 84.7% 44.4%
2wfwB02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 39.0 3.74e-01 78.0% 82.1%
4opmA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 47.0 2.98e-01 100.0% 94.0%
3b82A06 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 44.0 3.55e-01 94.9% 51.2%
3jyyA01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.53 43.0 3.35e-01 91.5% 64.2%
3oyyA02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 37.0 3.67e-01 76.3% 84.6%
1cjxA01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.52 42.0 3.23e-01 93.2% 40.7%
3l44A01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.52 43.0 3.19e-01 100.0% 54.6%
4q66D01 6.20.120.50 Special › Other non-globular › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.52 38.0 3.54e-01 78.0% 61.6%
2qpvA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.52 43.0 3.46e-01 100.0% 76.5%
4c5wA01 3.30.2020.30 Alpha Beta › 2-Layer Sandwich › NE0471 N-terminal domain-like › 0.51 38.0 3.32e-01 83.1% 96.9%
5ygqA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 44.0 3.02e-01 100.0% 84.9%
4rs6A01 3.30.1120.30 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › POLO box domain 0.51 43.0 3.53e-01 100.0% 80.5%
3cz8A02 3.10.50.10 Alpha Beta › Roll › Chitinase A; domain 3 › 0.50 34.0 3.52e-01 72.9% 73.7%
4hb9A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.50 43.0 2.67e-01 98.3% 87.7%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5081654 211.1.1.0 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.83 71.0 7.14e-01 98.3% 93.3%
4006548 331.19.1.2 a+b two layers › TBP-like › Toxin RnlA N-terminal domains › Toxin RnlA N-terminal domains › RnlA_toxin_N 0.70 52.0 4.48e-01 81.4% 80.0%
5023339 310.3.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.67 47.0 4.51e-01 74.6% 92.9%
1193916 3016.1.1.1 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 0.65 54.0 4.58e-01 94.9% 90.1%
3287428 211.1.1.11 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase_6 0.65 45.0 3.63e-01 74.6% 37.4%
3245032 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.64 46.0 4.30e-01 78.0% 97.3%
4120629 4.1.1.97 beta barrels › SH3 › SH3 › SH3 › DUF150_C 0.63 47.0 4.37e-01 79.7% 82.7%
5051148 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.63 46.0 4.60e-01 78.0% 96.7%
3264879 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.63 45.0 4.31e-01 76.3% 72.9%
4983311 2003.1.2.29 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › NAD_binding_8 0.63 43.0 2.62e-01 71.2% 35.6%
3533318 4.1.1.33 beta barrels › SH3 › SH3 › SH3 › Myosin_N 0.62 43.0 4.66e-01 72.9% 92.0%
3556601 4.1.1.304 beta barrels › SH3 › SH3 › SH3 › SH3-C_UBE2O 0.62 46.0 4.47e-01 78.0% 92.3%
3286115 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.62 53.0 4.31e-01 98.3% 84.3%
4113970 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.62 54.0 4.52e-01 100.0% 89.4%
3926120 4.1.1.169 beta barrels › SH3 › SH3 › SH3 › DUF4819 0.62 45.0 3.41e-01 78.0% 42.1%
5051419 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.62 46.0 4.73e-01 79.7% 98.2%
5038558 211.1.1.0 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.61 42.0 4.49e-01 72.9% 88.0%
4284398 211.1.1.0 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.61 41.0 4.33e-01 72.9% 84.0%
3420092 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.60 46.0 4.25e-01 86.4% 86.3%
4152624 375.1.1.17 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › tRNA-synt_1f 0.60 39.0 4.46e-01 71.2% 100.0%
3487936 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.60 42.0 3.98e-01 72.9% 77.1%
4026006 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.60 45.0 4.16e-01 84.7% 90.0%
3396594 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.60 42.0 4.21e-01 74.6% 95.0%
3804264 64.1.1.8 beta meanders › WW domain-like › WW domain › WW domain › DUF7028 0.60 46.0 4.15e-01 98.3% 60.0%
5023929 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.60 44.0 3.98e-01 81.4% 71.8%
1759242 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.59 51.0 4.30e-01 100.0% 77.5%
4954702 2008.1.1.114 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF4143 0.58 44.0 3.59e-01 84.7% 76.7%
5012656 330.5.1.0 a+b two layers › dsRBD-like › Bacillus phage protein › Bacillus phage protein 0.58 50.0 4.46e-01 98.3% 80.0%
3256431 4.1.1.360 beta barrels › SH3 › SH3 › SH3 › KOW, G-patch_2 0.58 42.0 3.85e-01 78.0% 62.5%
3687406 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.58 44.0 4.04e-01 86.4% 95.2%
3706181 5.1.4.44 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › RCC1_2 0.58 46.0 2.81e-01 94.9% 13.1%
4661064 252.1.1.1 a+b two layers › DNA-binding domain › Methyl-CpG-binding domain, MBD › Methyl-CpG-binding domain, MBD › MBD 0.58 41.0 4.17e-01 91.5% 76.3%
3387924 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.57 42.0 3.64e-01 79.7% 55.8%
1031172 4.1.1.113 beta barrels › SH3 › SH3 › SH3 › TraI_2B 0.57 44.0 4.20e-01 86.4% 84.7%
3511278 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.57 44.0 4.26e-01 88.1% 81.4%
3966081 211.1.1.1 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase 0.56 38.0 3.52e-01 72.9% 52.5%
4097002 2.1.1.48 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Elong-fact-P_C 0.56 40.0 4.07e-01 76.3% 86.4%
3567156 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.56 38.0 2.68e-01 74.6% 21.3%
4014812 4.8.1.2 beta barrels › SH3 › Chromo domain-like › Chromo domain-like › Chromo_shadow 0.56 38.0 3.83e-01 72.9% 71.7%
5058457 4.17.1.1 beta barrels › SH3 › GatD N-terminal domain-like › GatD N-terminal domain-like › GatD_N 0.55 40.0 3.93e-01 79.7% 90.8%
None 0.55 46.0 2.83e-01 98.3% 38.8%
3563220 4.1.1.220 beta barrels › SH3 › SH3 › SH3 › BAHCC1-like_Tudor 0.55 42.0 3.87e-01 86.4% 78.8%
4060102 2.1.1.48 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Elong-fact-P_C 0.55 40.0 4.03e-01 76.3% 93.1%
3992587 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.54 38.0 2.23e-01 76.3% 8.6%
3388785 109.1.1.11 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › Arc1p_N_like 0.54 45.0 3.35e-01 96.6% 37.0%
3520270 101.35.1.5 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH1 0.54 39.0 3.30e-01 78.0% 44.8%
3275111 5.1.4.304 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR11_2nd 0.54 39.0 2.49e-01 91.5% 13.8%
3701944 331.17.1.1 a+b two layers › TBP-like › Atp11 › Atp11 › ATP11 0.53 36.0 2.65e-01 71.2% 24.6%
5056802 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 45.0 2.94e-01 100.0% 23.7%
3914253 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.53 42.0 2.78e-01 86.4% 38.8%
3576046 211.1.1.0 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.53 36.0 3.81e-01 71.2% 84.0%
3400912 868.1.1.3 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › Med20 0.53 44.0 3.12e-01 100.0% 65.0%
3764706 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.53 38.0 2.64e-01 81.4% 51.6%
224080 2.14.1.2 beta barrels › OB-fold › HupF/HypC-like › HupF/HypC-like › CHS5_N 0.53 37.0 3.42e-01 78.0% 57.9%
4043931 2.1.1.9 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ribosomal_S4e 0.52 35.0 3.58e-01 79.7% 71.7%
3243143 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.52 39.0 3.89e-01 88.1% 92.3%
3197437 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 40.0 2.65e-01 93.2% 24.7%
391151 719.2.1.1 beta barrels › XRCC4, N-terminal domain-like › NE0471 N-terminal domain-like › NE0471 N-terminal domain-like › GBBH-like_N 0.51 38.0 3.24e-01 83.1% 89.5%
3277941 223.1.1.36 a+b three layers › Profilin-like › sensor domains › sensor domains › MLTR_LBD 0.51 40.0 3.03e-01 89.8% 80.6%
5061404 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.51 41.0 2.73e-01 100.0% 72.1%
4028871 2.1.1.10 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EFP 0.51 37.0 3.49e-01 79.7% 71.2%
4617844 7579.1.1.2 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Lipase 0.50 37.0 2.49e-01 89.8% 67.1%
5037511 2004.1.1.293 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 0.50 39.0 2.38e-01 86.4% 17.6%
4072958 2.1.1.9 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ribosomal_S4e 0.50 35.0 3.47e-01 79.7% 69.2%
D2 high residues 247-402
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF24308.2 best DUF7487 130.1 1.50e-37 66.0% 44.1%
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ajvC02 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.84 47.0 6.13e-01 79.5% 95.6%
2zyzC00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.78 43.0 5.47e-01 80.8% 89.6%
1a79A01 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.76 47.0 5.89e-01 80.8% 98.0%
2gw6A01 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.65 47.0 5.39e-01 79.5% 100.0%
4hn3A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.63 51.0 3.97e-01 84.6% 91.6%
1vsrA00 3.40.960.10 Alpha Beta › 3-Layer(aba) Sandwich › Endonuclease; Chain A › VSR Endonuclease 0.63 46.0 5.00e-01 76.3% 96.3%
3ib5A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.62 50.0 3.88e-01 84.6% 76.9%
3ieyB00 3.40.1350.150 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.62 48.0 4.91e-01 80.1% 82.9%
1ob8A00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.61 45.0 5.03e-01 94.9% 100.0%
3k93A00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.59 46.0 4.02e-01 80.1% 59.6%
3h4rA00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.59 46.0 4.12e-01 82.1% 64.8%
7n3yC01 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.59 51.0 3.92e-01 94.9% 81.5%
2eo0B00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.58 44.0 4.89e-01 87.8% 99.2%
2a1iA01 3.40.50.10130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 37.0 4.13e-01 78.2% 84.6%
1xmxA02 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.55 44.0 4.51e-01 86.5% 87.9%
6aikB00 3.40.50.10300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CoaB-like 0.55 45.0 3.60e-01 87.8% 84.4%
1sr4B00 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.54 46.0 3.96e-01 93.6% 83.3%
4bxoA01 3.40.50.10130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 40.0 4.25e-01 87.2% 90.4%
5f5nA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 41.0 3.37e-01 80.1% 92.7%
1j24A00 3.40.50.10130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 39.0 4.23e-01 86.5% 91.7%
1sgvA02 2.30.130.10 Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › PUA domain 0.52 22.0 3.31e-01 71.8% 93.7%
1shuX00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.52 42.0 4.06e-01 85.9% 92.3%
2bgwB01 3.40.50.10130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 39.0 4.24e-01 87.2% 93.9%
2xi5A00 3.40.91.60 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.52 42.0 3.98e-01 85.9% 83.7%
2vptA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.52 42.0 3.86e-01 85.9% 94.5%
2fgyA03 3.30.1330.140 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Carboxysome Shell Carbonic Anhydrase, C-terminal domain 0.51 35.0 3.94e-01 71.8% 94.0%
4esjA01 3.40.210.30 Alpha Beta › 3-Layer(aba) Sandwich › PvuII Endonuclease; Chain A › Dam replacing family, catalytic PD-(D/E)XK domain 0.50 42.0 4.26e-01 89.1% 93.6%
6xzqA01 3.40.91.90 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain 0.50 41.0 4.08e-01 87.2% 86.4%
ECOD (55)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4932500 2008.2.1.1 a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › tRNA_int_endo 0.76 50.0 6.08e-01 80.8% 100.0%
1392754 2008.2.1.1 a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › tRNA_int_endo 0.75 44.0 5.65e-01 80.8% 96.8%
5048373 2008.2.1.1 a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › tRNA_int_endo 0.74 45.0 5.49e-01 80.1% 91.4%
4940595 2008.1.1.14 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Vsr 0.74 45.0 5.59e-01 92.3% 96.0%
4995722 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.73 46.0 5.69e-01 84.0% 99.0%
4940296 2008.1.1.121 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › MTES_1575 0.72 44.0 5.47e-01 82.7% 97.9%
5073529 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.72 46.0 5.54e-01 85.3% 95.2%
4941326 2008.2.1.1 a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › tRNA_int_endo 0.71 45.0 5.46e-01 80.8% 95.2%
4937663 2008.2.1.1 a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › tRNA_int_endo 0.71 46.0 5.65e-01 80.8% 99.0%
4984120 2008.1.1.17 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF559 0.70 46.0 5.46e-01 82.1% 97.1%
4995749 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.70 47.0 5.57e-01 85.9% 97.2%
4935732 2008.1.1.165 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_MjaI 0.70 47.0 5.53e-01 92.3% 97.3%
3673147 2008.1.1.86 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RAP 0.70 44.0 5.07e-01 83.3% 86.1%
3163838 2008.1.1.17 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF559 0.69 45.0 5.17e-01 87.2% 88.7%
5041197 2008.1.1.30 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Tn7_TnsA-like_N 0.68 52.0 5.08e-01 92.3% 71.7%
3808239 2008.1.1.86 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RAP 0.68 43.0 5.25e-01 84.0% 99.0%
3969697 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.65 45.0 4.61e-01 80.1% 71.6%
4927469 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.64 49.0 5.40e-01 80.1% 99.2%
3196217 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.63 54.0 4.41e-01 90.4% 65.2%
3258001 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.63 49.0 5.16e-01 80.8% 94.3%
5056125 2008.1.1.14 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Vsr 0.62 47.0 5.11e-01 94.9% 92.3%
3281852 2008.1.1.14 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Vsr 0.62 45.0 4.74e-01 92.3% 80.7%
4501322 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.62 48.0 4.21e-01 80.8% 77.0%
4315832 2008.1.1.6 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UPF0102 0.62 43.0 4.96e-01 81.4% 97.4%
5062353 7601.1.1.1 a/b three-layered sandwiches › Lactate racemase N-terminal domain › Lactate racemase N-terminal domain › Lactate racemase N-terminal domain › Lar_N 0.62 46.0 4.04e-01 77.6% 82.6%
5021943 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.61 47.0 4.09e-01 81.4% 65.8%
5056974 2008.1.1.159 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Csa1 0.61 47.0 3.71e-01 81.4% 59.1%
4955559 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.61 45.0 5.00e-01 85.9% 100.0%
5022187 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.60 51.0 5.13e-01 95.5% 90.3%
4150493 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.59 50.0 4.47e-01 90.4% 69.9%
5064206 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.59 46.0 3.88e-01 81.4% 61.2%
4010258 2008.1.1.58 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF3799 0.58 45.0 3.85e-01 82.1% 66.8%
3656902 208.1.1.0 beta duplicates or obligate multimers › Single-stranded left-handed beta-helix › Trimeric LpxA-like enzymes › Trimeric LpxA-like enzymes 0.56 36.0 4.28e-01 81.4% 93.5%
5011372 306.6.1.0 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like 0.55 27.0 3.42e-01 74.4% 75.8%
4968040 2008.1.1.235 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF26618 0.55 42.0 4.56e-01 89.7% 97.7%
3988470 2008.1.1.51 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › McrBC 0.55 46.0 4.70e-01 90.4% 96.1%
5014287 327.11.1.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) 0.55 33.0 4.03e-01 76.9% 100.0%
1560740 2008.1.1.65 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › L_protein_N 0.55 43.0 3.56e-01 87.2% 47.9%
3512133 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.54 45.0 3.70e-01 89.1% 91.4%
4954341 2008.1.1.4 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 0.53 39.0 3.51e-01 81.4% 54.4%
4935626 2007.3.1.6 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Ligase_CoA_2 0.53 43.0 4.19e-01 85.9% 94.1%
4927733 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.53 40.0 3.96e-01 78.8% 87.3%
402316 2008.1.1.65 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › L_protein_N 0.52 42.0 3.99e-01 85.9% 84.2%
4936990 5104.1.1.3 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2 0.52 38.0 4.27e-01 94.9% 100.0%
3242288 2008.6.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Acetyl-CoA carboxylase AC4 and AC5 domains › Acetyl-CoA carboxylase AC4 and AC5 domains 0.51 43.0 4.16e-01 91.0% 99.4%
3415033 2008.1.1.27 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RAI1 0.51 40.0 3.05e-01 81.4% 61.9%
3415010 101.1.2.712 alpha arrays › HTH › HTH › winged helix domain › FNIP_C 0.51 45.0 3.79e-01 96.8% 89.4%
3553342 2005.1.1.36 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.51 38.0 3.66e-01 78.2% 84.9%
4078129 1.1.9.0 beta barrels › cradle loop barrel › RIFT-related › PUA domain 0.51 23.0 3.37e-01 72.4% 98.5%
3616535 2484.1.1.26 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi 0.51 36.0 2.99e-01 71.2% 75.4%
4069291 1.1.9.0 beta barrels › cradle loop barrel › RIFT-related › PUA domain 0.51 21.0 3.30e-01 71.8% 100.0%
5051064 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.50 39.0 3.39e-01 80.8% 85.4%
5000785 7502.1.1.0 a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS 0.50 36.0 3.48e-01 87.8% 66.5%
1503110 2008.1.1.21 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DpnI 0.50 44.0 4.28e-01 96.2% 92.4%
3507923 2484.1.1.26 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi 0.50 37.0 3.10e-01 78.2% 67.7%
D3 medium residues 108-179
PDB