Back to structures

N5_271_007G1_scaffold_5_prodigal-single.1__X__X__00115

Bact-Vir

N5_271_007G1_scaffold_5_prodigal-single.1__X__X__00115

Identity

Kingdom:
phage

Quality

85.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-81
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1yy7A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 49.0 4.50e-01 80.2% 81.9%
2hsnA02 1.20.1050.110 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 47.0 4.31e-01 76.5% 65.4%
8agyA01 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.64 46.0 3.32e-01 76.5% 66.4%
2imiB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 52.0 4.37e-01 90.1% 92.9%
4c0eA01 1.25.40.790 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 50.0 3.46e-01 85.2% 27.6%
3zheD01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 45.0 3.40e-01 79.0% 29.8%
3ibhA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 47.0 4.23e-01 81.5% 85.6%
3vhlA02 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.63 48.0 4.25e-01 82.7% 76.7%
7wf8B01 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.61 43.0 3.88e-01 91.4% 51.2%
5xfaA04 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.60 47.0 4.72e-01 88.9% 83.5%
1lshA02 1.25.10.20 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Vitellinogen, superhelical 0.59 44.0 2.98e-01 85.2% 19.7%
1i0zA02 3.90.110.10 Alpha Beta › Alpha-Beta Complex › L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2 › Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal 0.57 40.0 3.15e-01 72.8% 86.3%
3t57A02 1.20.1180.10 Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain 0.56 41.0 4.31e-01 93.8% 84.0%
2n1rA00 1.10.150.90 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17 0.54 41.0 3.51e-01 82.7% 53.7%
3kh1A00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.53 41.0 3.23e-01 87.7% 69.7%
3qa8A04 1.20.1270.250 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.50 39.0 2.78e-01 82.7% 78.1%
4m88A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 40.0 3.02e-01 88.9% 80.2%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3335438 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.58 48.0 4.60e-01 91.4% 98.9%
4464578 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.58 42.0 4.46e-01 76.5% 100.0%
3251141 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.58 40.0 3.72e-01 72.8% 60.0%
3806318 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.57 48.0 4.48e-01 92.6% 96.0%
3959617 4033.1.1.0 alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like 0.57 41.0 3.71e-01 75.3% 63.6%
3261684 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.56 39.0 3.96e-01 72.8% 80.0%
3473295 101.1.1.3 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-binding 0.56 35.0 3.48e-01 70.4% 60.0%
3681983 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 40.0 3.85e-01 79.0% 74.0%
3809039 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.55 42.0 4.24e-01 86.4% 100.0%
3507677 101.35.1.25 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › PF26215 0.54 41.0 3.99e-01 82.7% 75.3%
3673819 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.54 37.0 3.84e-01 71.6% 84.0%
D2 medium residues 82-153
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4cc9B00 1.20.5.4730 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.73 47.0 4.22e-01 91.7% 48.0%
2j82A00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.70 49.0 3.44e-01 88.9% 24.0%
3h6pC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.61 45.0 5.01e-01 88.9% 100.0%
2bg1A01 3.90.1310.40 Alpha Beta › Alpha-Beta Complex › Penicillin-binding protein 2a (Domain 2) › 0.59 43.0 4.28e-01 86.1% 72.7%
4m0mA03 1.20.1270.430 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 41.0 4.02e-01 76.4% 91.1%
1iuqA01 1.10.1200.50 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal 0.57 45.0 4.46e-01 87.5% 98.7%
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.55 43.0 4.30e-01 93.1% 80.8%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.54 37.0 3.91e-01 72.2% 92.4%
2rt6A00 1.20.1270.340 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.53 45.0 4.04e-01 90.3% 92.9%
5xtck00 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.50 44.0 4.03e-01 98.6% 75.3%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1124196 3788.1.1.1 alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › VPR 0.73 47.0 4.22e-01 91.7% 48.0%
4179237 6028.1.1.0 alpha bundles › Ribosome modulation factor › Ribosome modulation factor › Ribosome modulation factor 0.71 41.0 4.34e-01 70.8% 64.6%
1066185 130.1.1.1 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › SAP 0.67 47.0 5.30e-01 83.3% 98.1%
3489683 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.66 52.0 5.22e-01 98.6% 84.0%
3994610 130.1.1.0 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.64 51.0 5.30e-01 91.7% 95.4%
3685214 632.18.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.62 48.0 4.54e-01 81.9% 96.5%
4872161 1131.1.1.1 extended segments › Mitochondrial complex I, B14.5b subunit › Mitochondrial complex I, B14.5b subunit › Mitochondrial complex I, B14.5b subunit › NDUF_C2 0.61 51.0 4.23e-01 88.9% 80.8%
3930571 130.1.1.0 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.61 48.0 4.86e-01 83.3% 88.6%
4025313 3721.1.1.1 alpha bundles › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › VIT1 0.60 44.0 4.48e-01 79.2% 97.1%
4965739 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.59 51.0 4.90e-01 93.1% 91.3%
147067 3276.1.1.1 alpha arrays › N-terminal domain in MogR repressor › N-terminal domain in MogR repressor › N-terminal domain in MogR repressor › MogR_DNAbind 0.58 38.0 4.02e-01 100.0% 76.6%
3868871 213.1.1.1 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.56 49.0 3.56e-01 100.0% 86.3%
3236900 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.55 46.0 4.51e-01 95.8% 88.7%
4104279 2004.1.1.71 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IPPT 0.54 45.0 3.16e-01 95.8% 84.9%
2708987 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.53 43.0 4.24e-01 93.1% 81.3%
4054259 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.51 35.0 3.48e-01 70.8% 88.0%
3204035 1.1.17.4 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_S64 0.51 46.0 2.95e-01 100.0% 29.1%
3583564 130.1.1.1 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › SAP 0.51 39.0 3.98e-01 94.4% 88.6%
D3 medium residues 154-211
PDB
Domain cluster: representative
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3di5A00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.72 63.0 4.70e-01 100.0% 60.4%
3h6pC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 55.0 5.61e-01 84.5% 89.3%
4gzrC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 61.0 6.09e-01 100.0% 96.7%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.69 59.0 5.70e-01 98.3% 84.6%
3k8pC01 1.20.58.1440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 49.0 4.07e-01 98.3% 42.9%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.68 54.0 5.07e-01 100.0% 70.4%
4hhyC01 1.20.142.10 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain 0.68 53.0 4.15e-01 87.9% 52.7%
4mx8C01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.67 43.0 3.02e-01 79.3% 20.1%
5iduC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.66 58.0 4.26e-01 100.0% 54.7%
3gv5B01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.66 45.0 3.47e-01 93.1% 31.1%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 56.0 3.80e-01 100.0% 41.0%
4iggB06 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 55.0 3.72e-01 100.0% 72.1%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.62 51.0 4.75e-01 100.0% 71.4%
2zj2A03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 42.0 3.73e-01 84.5% 51.2%
1csmA00 1.10.590.10 Mainly Alpha › Orthogonal Bundle › Chorismate Mutase, subunit A › Chorismate mutase, AroQ class superfamily, eukaryotic 0.60 52.0 3.42e-01 100.0% 61.1%
1kf6C00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.60 51.0 4.03e-01 100.0% 50.0%
4yk8B00 3.30.900.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain 0.60 51.0 3.56e-01 96.6% 92.3%
2qkdA04 2.60.120.1040 Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain 0.59 50.0 3.89e-01 94.8% 63.8%
1f45B00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.59 53.0 4.02e-01 100.0% 44.4%
1t94B02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.58 48.0 3.94e-01 98.3% 88.2%
4z7fB00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.58 49.0 3.58e-01 96.6% 33.9%
3r4iA02 6.10.140.960 Special › Helix non-globular › Helix Hairpins › 0.57 39.0 3.89e-01 70.7% 70.0%
7dklA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 47.0 3.83e-01 96.6% 93.0%
2fsjA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.56 46.0 3.49e-01 91.4% 46.4%
3qdkA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.55 45.0 2.87e-01 89.7% 66.8%
3fk5A02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.53 47.0 3.56e-01 100.0% 50.7%
3lkdA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 35.0 2.34e-01 72.4% 23.8%
3ll3B02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.52 42.0 2.90e-01 100.0% 43.7%
1go4A00 3.30.900.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain 0.51 44.0 3.09e-01 98.3% 30.1%
1e8cA01 3.40.1390.10 Alpha Beta › 3-Layer(aba) Sandwich › Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 › MurE/MurF, N-terminal domain 0.50 38.0 3.26e-01 84.5% 83.2%
5hvqC02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 37.0 3.25e-01 84.5% 58.2%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5013274 5011.1.1.0 extended segments › Bacterial ba3 type cytochrome c oxidase subunit IIa › Bacterial ba3 type cytochrome c oxidase subunit IIa › Bacterial ba3 type cytochrome c oxidase subunit IIa 0.77 42.0 3.65e-01 70.7% 36.5%
4999891 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.76 55.0 4.43e-01 75.9% 53.3%
3787647 192.2.1.31 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › PRA1 0.71 56.0 4.69e-01 93.1% 50.0%
5028061 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.71 61.0 5.33e-01 100.0% 63.3%
3553628 109.4.1.120 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Kinetochor_Ybp2 0.71 60.0 3.75e-01 100.0% 17.7%
3739470 192.2.1.31 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › PRA1 0.70 55.0 4.13e-01 93.1% 34.5%
4496758 5050.1.1.86 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › LysE 0.70 60.0 4.19e-01 100.0% 62.9%
4940192 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.68 57.0 4.69e-01 100.0% 50.0%
5029847 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.67 52.0 4.86e-01 94.8% 68.0%
4984959 3758.1.1.113 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › Rad50_zn_hook 0.66 55.0 3.50e-01 98.3% 18.8%
5007248 5065.1.1.3 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 0.65 56.0 3.70e-01 100.0% 72.7%
4954786 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.65 56.0 5.01e-01 100.0% 74.1%
5007377 633.6.1.3 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › HpaB 0.64 56.0 3.96e-01 98.3% 32.6%
3943611 601.27.1.2 alpha bundles › Four-helical up-and-down bundle › MW0975(SA0943)-like › MW0975(SA0943)-like › DUF3053 0.64 57.0 3.90e-01 100.0% 59.5%
4933888 5051.1.1.10 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2 0.64 56.0 3.26e-01 98.3% 13.5%
3958437 633.6.1.4 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_2 0.64 55.0 3.98e-01 100.0% 55.5%
3544489 192.1.1.12 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › PH_19 0.64 50.0 5.04e-01 89.7% 86.7%
5073710 633.6.1.3 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › HpaB 0.64 56.0 3.83e-01 100.0% 40.5%
3228937 5054.1.1.2 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.64 56.0 3.61e-01 100.0% 29.3%
4203273 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.63 54.0 3.67e-01 96.6% 92.6%
2637734 109.4.1.165 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Dsl1_C 0.63 54.0 3.45e-01 100.0% 43.1%
3596821 4268.2.1.0 alpha duplicates or obligate multimers › EspA/CesA-like › EspA chaperone CesA › EspA chaperone CesA 0.62 55.0 4.42e-01 100.0% 80.0%
3407715 109.4.1.546 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Ecm29 0.62 49.0 3.02e-01 86.2% 29.3%
4191686 3236.2.1.8 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › Asp-Al_Ex 0.61 48.0 2.91e-01 86.2% 14.0%
4889133 1030.1.1.1 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Csm2_III-A 0.61 50.0 3.98e-01 94.8% 74.6%
3906123 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 52.0 4.22e-01 100.0% 73.0%
3312373 148.1.3.207 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › DUF7751 0.60 46.0 3.82e-01 84.5% 80.0%
5041648 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.60 50.0 3.59e-01 100.0% 55.3%
3702921 148.1.3.10 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_6 0.60 43.0 4.04e-01 87.9% 61.3%
4027404 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.59 50.0 4.38e-01 100.0% 73.7%
4235807 3236.2.1.8 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › Asp-Al_Ex 0.59 48.0 2.90e-01 89.7% 14.9%
5063751 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.58 42.0 4.22e-01 77.6% 75.0%
3550678 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.57 47.0 3.40e-01 93.1% 44.4%
4643781 3236.1.1.16 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Asp-Al_Ex 0.56 47.0 2.91e-01 98.3% 36.3%
5025634 2484.1.1.87 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MreB-like_C 0.56 47.0 3.38e-01 93.1% 41.2%
3214571 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.56 47.0 3.88e-01 100.0% 57.4%
4512738 3236.1.1.16 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Asp-Al_Ex 0.56 44.0 2.68e-01 89.7% 73.0%
4348123 3236.1.1.16 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Asp-Al_Ex 0.55 47.0 2.97e-01 100.0% 39.7%
3925864 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 48.0 3.27e-01 98.3% 44.7%
4067008 3236.2.1.8 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › Asp-Al_Ex 0.55 49.0 2.99e-01 100.0% 58.7%
4287267 3236.2.1.8 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › Asp-Al_Ex 0.55 47.0 2.91e-01 98.3% 86.8%
4077718 3236.1.1.16 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Asp-Al_Ex 0.55 47.0 2.91e-01 100.0% 36.6%
3949649 3646.1.1.1 alpha complex topology › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › CbiQ 0.53 45.0 2.92e-01 94.8% 21.7%
4991135 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.53 48.0 3.91e-01 100.0% 58.1%
3728141 2003.1.1.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N 0.52 39.0 2.70e-01 81.0% 96.1%
3327035 3959.1.1.1 alpha duplicates or obligate multimers › Protein Hikeshi dimerization domain › Protein Hikeshi dimerization domain › Protein Hikeshi dimerization domain › Hikeshi-like_C 0.51 39.0 4.00e-01 84.5% 89.1%
3607656 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.50 39.0 3.43e-01 87.9% 95.8%
D4 medium residues 259-299_366-388_409-457
PDB
Domain cluster: representative
CATH (41)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3jzmA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.77 73.0 5.48e-01 100.0% 63.3%
2b8tA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 67.0 6.23e-01 100.0% 97.1%
2orwB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 65.0 6.29e-01 100.0% 96.9%
5kwaA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 65.0 5.60e-01 100.0% 72.2%
8alzB05 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 60.0 4.90e-01 98.2% 81.5%
7jgsG01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 61.0 5.34e-01 100.0% 87.3%
5agaA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 61.0 4.94e-01 100.0% 84.2%
5jajA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 60.0 4.53e-01 99.1% 69.0%
5dcaA09 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 60.0 4.82e-01 99.1% 80.5%
8jx6B01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 60.0 4.90e-01 100.0% 84.5%
1yksA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 58.0 4.83e-01 94.7% 92.2%
2xgjB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 58.0 4.74e-01 99.1% 73.8%
2pjuC01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.64 33.0 3.47e-01 100.0% 54.0%
6znpA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 57.0 4.61e-01 98.2% 81.1%
7nadx02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 56.0 4.34e-01 99.1% 66.7%
1xdwA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 51.0 4.21e-01 90.3% 94.9%
6vsxA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 55.0 4.87e-01 100.0% 97.5%
3kxqA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.58 45.0 3.53e-01 82.3% 78.9%
7e7gA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.57 48.0 3.78e-01 93.8% 81.8%
4azsA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 47.0 3.86e-01 91.2% 72.1%
4xcxA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 48.0 3.90e-01 92.0% 77.8%
3bgvD00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 47.0 3.61e-01 91.2% 79.1%
2nxcA03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 47.0 4.26e-01 90.3% 88.2%
3jwhA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 45.0 3.82e-01 86.7% 94.8%
3cc8A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 45.0 3.70e-01 87.6% 75.4%
3l8dA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 44.0 3.72e-01 86.7% 93.6%
1xxlA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 46.0 3.65e-01 90.3% 70.1%
2ykgA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 46.0 4.75e-01 90.3% 99.1%
2yogA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 49.0 4.11e-01 100.0% 81.2%
2pz0B00 3.20.20.190 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphatidylinositol (PI) phosphodiesterase 0.54 47.0 3.73e-01 98.2% 92.6%
1eepA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 48.0 3.51e-01 100.0% 66.2%
3r2gA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 46.0 3.43e-01 99.1% 83.0%
2og9A02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.52 41.0 3.33e-01 85.0% 68.7%
3n75A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 43.0 4.14e-01 100.0% 79.1%
2xr1B04 3.40.50.10890 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 45.0 3.97e-01 100.0% 89.2%
3egiA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 44.0 3.69e-01 94.7% 84.1%
4qdjA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 41.0 3.39e-01 86.7% 80.3%
4c5cA01 3.40.50.20 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 36.0 4.05e-01 100.0% 97.6%
1t57A00 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.51 40.0 3.44e-01 85.0% 97.8%
4c6rA00 3.40.50.10140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain 0.51 43.0 3.91e-01 96.5% 81.5%
1i4wA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 42.0 3.32e-01 92.0% 92.3%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4942853 2004.1.1.146 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.79 75.0 5.02e-01 100.0% 80.5%
4980355 2004.1.1.1219 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF7504 0.74 70.0 5.39e-01 100.0% 77.0%
5078444 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.71 67.0 5.21e-01 100.0% 74.2%
4890928 2004.1.1.93 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Dynein_heavy 0.68 63.0 4.49e-01 100.0% 43.8%
3628354 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.66 60.0 4.78e-01 98.2% 74.5%
4948563 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.66 61.0 4.90e-01 99.1% 75.0%
3488779 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.66 60.0 4.61e-01 98.2% 66.5%
4299663 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.66 60.0 4.83e-01 98.2% 76.7%
None 0.65 60.0 3.64e-01 100.0% 23.2%
None 0.64 59.0 4.36e-01 99.1% 76.7%
3721132 2004.1.1.56 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.64 60.0 5.09e-01 100.0% 80.6%
5045954 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.64 58.0 4.69e-01 98.2% 78.1%
4023933 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.64 58.0 4.64e-01 99.1% 83.6%
3668912 2004.1.1.56 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.64 59.0 5.04e-01 100.0% 80.0%
3595556 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.63 58.0 4.69e-01 100.0% 85.7%
3273368 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.63 57.0 4.73e-01 100.0% 82.0%
4950792 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 57.0 4.28e-01 100.0% 94.1%
4797722 2004.1.1.151 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Flavi_DEAD 0.62 52.0 4.96e-01 90.3% 100.0%
4999742 2004.1.1.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.62 57.0 5.27e-01 100.0% 87.1%
3941193 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.62 57.0 4.71e-01 100.0% 83.6%
3458338 2004.1.1.56 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.62 57.0 4.86e-01 100.0% 75.4%
3455774 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 56.0 4.58e-01 100.0% 90.2%
3715963 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.61 56.0 4.56e-01 100.0% 78.5%
3393299 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 55.0 4.78e-01 100.0% 91.2%
4512625 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.57 47.0 3.70e-01 91.2% 72.2%
5002289 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.57 45.0 4.43e-01 91.2% 78.3%
3587086 2003.1.5.79 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.57 47.0 3.76e-01 89.4% 70.9%
4959355 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.57 50.0 3.91e-01 98.2% 53.7%
5046553 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.57 52.0 4.35e-01 99.1% 95.8%
5080913 2003.1.5.20 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MethyltransfD12 0.57 47.0 3.08e-01 90.3% 37.6%
3800790 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.56 46.0 3.97e-01 90.3% 84.9%
3281121 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.56 46.0 3.60e-01 91.2% 67.1%
3386783 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.55 46.0 4.29e-01 92.0% 83.4%
4998190 2003.1.5.82 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.55 43.0 3.44e-01 85.8% 88.6%
5081595 2003.1.5.79 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.54 45.0 3.75e-01 91.2% 83.9%
3710846 2003.1.5.82 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.54 45.0 3.54e-01 91.2% 65.3%
4183675 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.54 44.0 4.31e-01 100.0% 80.8%
5033880 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.54 44.0 3.69e-01 91.2% 93.7%
3938787 7512.1.1.1 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT 0.53 46.0 3.54e-01 100.0% 81.1%
5025437 2002.1.1.29 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DHDPS 0.53 46.0 3.44e-01 96.5% 98.6%
3671327 2007.1.3.28 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Glyco_transf_61 0.53 41.0 3.27e-01 82.3% 61.3%
3952572 7558.1.1.1 a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Acyltransferase 0.52 47.0 3.67e-01 100.0% 82.8%
4130138 2003.1.5.53 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.52 44.0 3.12e-01 94.7% 82.9%
3835401 2007.9.1.1 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR 0.52 42.0 3.89e-01 87.6% 72.4%
4528832 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.52 43.0 3.59e-01 91.2% 76.0%
3666801 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.52 37.0 3.13e-01 76.1% 65.9%
3258501 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.52 39.0 3.68e-01 100.0% 64.1%
4043415 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 46.0 3.10e-01 100.0% 28.7%
3263152 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.51 42.0 3.32e-01 92.0% 64.7%
5048441 2003.1.5.82 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.51 43.0 3.51e-01 91.2% 83.3%
4968562 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.51 46.0 4.10e-01 100.0% 80.0%
4105273 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.51 41.0 3.30e-01 90.3% 91.0%
4998635 7518.1.1.1 a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.51 36.0 3.44e-01 100.0% 63.1%
4972422 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.51 41.0 3.24e-01 91.2% 75.8%
5050006 7518.1.1.1 a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.50 37.0 3.48e-01 100.0% 62.9%
3204758 7579.1.1.13 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DLH 0.50 42.0 3.38e-01 93.8% 78.7%
D5 medium residues 458-513
PDB
Domain cluster: representative
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3netB02 3.40.50.800 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain 0.82 53.0 4.27e-01 80.4% 37.8%
3bh0A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.81 63.0 3.94e-01 83.9% 17.6%
3lxqA01 3.30.1120.80 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.80 55.0 4.52e-01 100.0% 40.4%
2cvhA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.76 54.0 3.59e-01 85.7% 19.6%
4q97A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.71 51.0 4.11e-01 76.8% 70.4%
4a8jB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.67 53.0 3.52e-01 87.5% 30.5%
3fgbA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.67 58.0 3.58e-01 100.0% 41.8%
1nlfA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 56.0 3.69e-01 98.2% 24.0%
1pjxA00 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.66 56.0 3.52e-01 98.2% 32.5%
1a7tA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.63 53.0 3.60e-01 100.0% 89.0%
4ebgA00 3.10.450.560 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.62 52.0 4.46e-01 100.0% 57.7%
2wozA00 2.120.10.80 Mainly Beta › 6 Propeller › Neuraminidase › Kelch-type beta propeller 0.61 51.0 3.27e-01 100.0% 26.7%
4qrlA00 2.40.128.280 Mainly Beta › Beta Barrel › Lipocalin › 0.61 42.0 3.48e-01 85.7% 38.2%
2f86B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 47.0 3.73e-01 91.1% 45.7%
3lygA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 46.0 3.67e-01 89.3% 40.8%
3db0B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.59 47.0 3.73e-01 91.1% 84.7%
2x5gA00 3.30.720.60 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.59 49.0 4.27e-01 100.0% 59.3%
3q9oA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.58 51.0 3.43e-01 100.0% 55.6%
3pg4A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.58 48.0 3.28e-01 100.0% 90.0%
3hx8A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.58 47.0 3.71e-01 96.4% 49.2%
4e72A01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.58 43.0 3.38e-01 82.1% 37.1%
6r2nA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 41.0 3.15e-01 78.6% 92.1%
1a5yA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.57 46.0 2.95e-01 91.1% 22.2%
4kt3B00 3.10.450.170 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › type vi secretion system effector-immunity co pseudomonas protegens 0.57 43.0 3.46e-01 87.5% 68.8%
2x45A00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.57 41.0 3.19e-01 82.1% 32.6%
1qqgA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 48.0 4.01e-01 100.0% 80.6%
5jenA01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.56 41.0 3.29e-01 82.1% 39.6%
1yrtA02 3.90.1760.10 Alpha Beta › Alpha-Beta Complex › Adenylylcyclase toxin fold › Anthrax toxin, edema factor, central domain 0.55 43.0 3.31e-01 91.1% 36.8%
2euiA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.55 43.0 3.32e-01 89.3% 59.3%
1oqwA00 3.30.700.10 Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin › Glycoprotein, Type 4 Pilin 0.54 43.0 3.26e-01 91.1% 43.8%
1vhzA01 3.90.79.10 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase 0.53 39.0 2.85e-01 82.1% 62.9%
3cygA01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.52 39.0 3.12e-01 87.5% 38.7%
8a9nA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.52 42.0 3.24e-01 91.1% 61.8%
1qhlA00 3.40.1140.10 Alpha Beta › 3-Layer(aba) Sandwich › N-terminal domain of mukB › 0.51 40.0 2.91e-01 98.2% 64.5%
1a1aB00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.51 41.0 3.53e-01 100.0% 91.2%
3licA01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.50 36.0 2.65e-01 80.4% 38.2%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3942586 2004.1.1.107 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DnaB_C 0.86 71.0 4.50e-01 91.1% 19.2%
4995772 2004.1.1.107 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DnaB_C 0.83 69.0 4.32e-01 96.4% 18.2%
3274280 2004.1.1.200 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_25 0.79 62.0 3.97e-01 100.0% 17.8%
3807885 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.76 66.0 3.88e-01 96.4% 12.9%
4994819 2004.1.1.162 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad51 0.75 61.0 3.96e-01 100.0% 20.1%
3297023 2004.1.1.200 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_25 0.73 64.0 4.07e-01 98.2% 21.2%
4171287 2004.1.1.162 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad51 0.73 58.0 3.87e-01 100.0% 21.9%
4931272 220.1.1.76 beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_2 0.71 49.0 4.07e-01 78.6% 42.1%
3445610 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.71 62.0 4.20e-01 100.0% 29.8%
3354564 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.68 51.0 5.04e-01 82.1% 93.3%
4930531 243.1.1.0 a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.68 50.0 4.10e-01 80.4% 51.4%
4879161 330.1.1.6 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Staufen_C 0.65 45.0 4.26e-01 80.4% 60.3%
3925971 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 50.0 3.43e-01 91.1% 22.7%
3801858 252.1.1.0 a+b two layers › DNA-binding domain › Methyl-CpG-binding domain, MBD › Methyl-CpG-binding domain, MBD 0.64 49.0 4.83e-01 92.9% 78.3%
3624410 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.64 55.0 3.36e-01 100.0% 39.7%
5035584 375.1.1.31 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Elf1 0.63 47.0 4.21e-01 82.1% 56.2%
3248369 5.1.3.137 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1, Kelch_2, Kelch_KLHDC2_KLHL20_DRC7 0.63 53.0 3.33e-01 100.0% 31.5%
3929694 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.63 55.0 3.20e-01 100.0% 19.0%
4969137 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.63 47.0 4.46e-01 89.3% 67.1%
5052205 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.62 50.0 2.89e-01 100.0% 8.2%
3258701 192.8.1.295 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Spindle_Spc25 0.61 47.0 3.13e-01 91.1% 21.4%
3451388 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 48.0 3.14e-01 92.9% 23.9%
3255969 2004.1.1.174 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Elong_Iki1 0.60 51.0 3.34e-01 98.2% 22.9%
3523657 5.1.4.18 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › EPTP 0.60 49.0 3.07e-01 100.0% 35.3%
3994368 5.1.8.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › putative conserved lipoprotein NT01CX_1156 › APEH_N 0.60 51.0 3.48e-01 100.0% 51.1%
3205306 5.1.3.137 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1, Kelch_2, Kelch_KLHDC2_KLHL20_DRC7 0.60 49.0 3.15e-01 100.0% 33.3%
3320817 2004.1.1.174 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Elong_Iki1 0.60 46.0 3.04e-01 91.1% 22.4%
2441964 11.32.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › Calcium-dependent cell adhesion molecule-1 C-terminal domain › Calcium-dependent cell adhesion molecule-1 C-terminal domain › Membrane_bind 0.60 47.0 3.79e-01 89.3% 61.9%
4949036 375.1.1.21 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-ZPR1 0.59 44.0 4.59e-01 91.1% 92.0%
3192570 5.1.4.35 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Lactonase 0.58 48.0 3.02e-01 100.0% 26.2%
3636168 2484.1.1.32 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FGGY_C 0.58 47.0 2.74e-01 89.3% 12.0%
4346988 214.1.1.6 a+b two layers › SH2 › SH2 › SH2 › SH2_2 0.58 42.0 3.54e-01 82.1% 42.9%
3268229 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 50.0 4.07e-01 100.0% 91.4%
3258377 331.23.1.0 a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain 0.56 42.0 3.68e-01 89.3% 52.2%
5011152 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.56 43.0 4.34e-01 91.1% 87.3%
3866143 5.1.3.2 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Ldl_recept_b 0.53 42.0 2.87e-01 100.0% 35.3%
3917376 4.1.1.239 beta barrels › SH3 › SH3 › SH3 › SH3-B_UBE2O 0.53 45.0 4.27e-01 100.0% 84.3%
3993689 4099.1.1.0 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.52 40.0 3.79e-01 92.9% 69.3%
4522761 3308.1.1.0 beta duplicates or obligate multimers › periplasmic lysozyme inhibitor of I-type lysozyme-like › periplasmic lysozyme inhibitor of I-type lysozyme › periplasmic lysozyme inhibitor of I-type lysozyme 0.50 43.0 3.52e-01 100.0% 90.9%