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NAD-dependent_DNA_ligase

Euk-Vir

Aureococcus_anophagefferens_virus

NAD-dependent_DNA_ligase__YP_009052200__Aureococcus_anophagefferens_virus__1474867

Identity

Accession:
YP_009052200 ↗
Protein ID:
NAD-dependent_DNA_ligase
Kingdom:
euk

Quality

76.5 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Imitervirales› Schizomimiviridae› Kratosvirus› Aureococcus_anophagefferens_virus

TaxID: 1474867

Cluster

View cluster (18 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 36-102
PDB
D2 high residues 586-651
PDB
Domain cluster: rep: MN095770.1__QFR57709.1__CPT_Slocum_152__00129__D178-251
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00533.34 best BRCT 33.2 6.90e-08 93.9% 68.0%
PF12738.14 PTCB-BRCT 24.2 3.70e-05 87.9% 77.8%
CATH (90)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2nteB01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.87 80.0 6.91e-01 100.0% 75.8%
3oq0J00 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.87 80.0 7.00e-01 100.0% 91.6%
1l0bA01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.85 77.0 6.53e-01 100.0% 72.9%
2azmA01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.85 74.0 6.38e-01 100.0% 62.4%
7p0jA01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.84 76.0 6.86e-01 100.0% 82.2%
3olcX03 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.82 74.0 6.74e-01 100.0% 78.2%
4bu0A02 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.82 75.0 6.85e-01 100.0% 79.8%
3olcX02 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.82 74.0 6.43e-01 100.0% 68.4%
3hufB02 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.81 74.0 6.40e-01 100.0% 66.7%
4bu0A01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.81 73.0 6.37e-01 100.0% 69.4%
4bmdA02 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.79 71.0 6.22e-01 100.0% 73.7%
1cdzA00 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.79 71.0 6.25e-01 100.0% 72.9%
6j0yA01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.79 70.0 6.10e-01 100.0% 72.3%
3jveA00 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.79 70.0 6.22e-01 100.0% 73.7%
2d8mA01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.78 70.0 6.28e-01 100.0% 71.7%
6zpkA01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.78 69.0 6.37e-01 100.0% 81.4%
3gqwB01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.78 70.0 4.21e-01 100.0% 18.8%
1gzhB01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.77 69.0 5.97e-01 100.0% 76.7%
5jc8C00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.77 69.0 4.62e-01 100.0% 86.9%
1wf6A01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.77 69.0 5.68e-01 100.0% 58.5%
1ax4A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.76 69.0 4.53e-01 100.0% 62.6%
3ff4A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.75 66.0 5.43e-01 100.0% 92.6%
4y9dA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.75 67.0 4.53e-01 100.0% 83.4%
4bmdA01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.75 66.0 5.99e-01 100.0% 73.0%
2couA01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.74 66.0 5.99e-01 100.0% 75.3%
4yacA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.74 66.0 4.52e-01 100.0% 90.4%
6qp2A01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.74 66.0 4.46e-01 98.5% 57.7%
3l41A01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.74 65.0 5.71e-01 100.0% 69.3%
2kpoA00 3.40.50.11230 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.74 66.0 5.56e-01 100.0% 82.7%
5f5nA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.74 66.0 4.27e-01 100.0% 64.7%
3phhA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.74 65.0 5.19e-01 98.5% 90.0%
4rk6A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.73 66.0 5.29e-01 100.0% 87.3%
2o1sB03 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.73 64.0 5.18e-01 100.0% 83.5%
2bd0A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.72 63.0 4.36e-01 100.0% 91.9%
1y81A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.72 63.0 5.25e-01 100.0% 95.7%
3fdbA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.71 62.0 4.34e-01 98.5% 59.4%
3shtA02 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.71 58.0 5.26e-01 100.0% 66.7%
5v7nA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.71 62.0 4.98e-01 100.0% 78.9%
2duwA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.71 61.0 4.89e-01 100.0% 84.7%
1q0qA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.71 59.0 4.60e-01 95.5% 98.7%
3tjrA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.70 62.0 4.16e-01 100.0% 80.5%
5gizA01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.70 61.0 4.96e-01 100.0% 85.3%
3eagA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.70 54.0 4.95e-01 87.9% 96.8%
2coeA01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.70 61.0 5.48e-01 100.0% 80.6%
6pexA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.69 61.0 4.93e-01 100.0% 84.4%
4g2nA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.69 61.0 4.92e-01 100.0% 86.8%
4i9fA02 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.69 59.0 4.99e-01 97.0% 84.8%
1zemA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.69 60.0 4.03e-01 100.0% 91.2%
1c4kA01 3.40.50.220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.69 61.0 5.23e-01 100.0% 81.9%
4mamA01 3.40.50.20 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.69 54.0 4.86e-01 87.9% 91.6%
4p4gA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.68 58.0 4.69e-01 100.0% 89.2%
1yqgA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.68 60.0 4.65e-01 100.0% 94.6%
7mjzA01 3.40.50.12160 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Methylthiotransferase, N-terminal domain 0.68 58.0 4.84e-01 100.0% 86.9%
1xdwA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.68 59.0 4.74e-01 100.0% 87.2%
1u2pA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.67 59.0 4.50e-01 100.0% 92.9%
1gdhA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.67 59.0 4.78e-01 100.0% 90.6%
4lpsA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.67 57.0 4.08e-01 100.0% 81.9%
3d6kA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.67 57.0 3.93e-01 98.5% 56.1%
8a57D01 3.40.50.11060 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › GTPase HflX, N-terminal domain 0.65 56.0 4.95e-01 100.0% 99.0%
1h9cA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.65 55.0 4.84e-01 100.0% 82.1%
1yw4B00 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.65 55.0 3.67e-01 100.0% 59.5%
3kb6A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.65 57.0 4.59e-01 100.0% 82.4%
6jdrA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 54.0 4.28e-01 97.0% 74.1%
3ujpA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.63 54.0 4.61e-01 100.0% 87.0%
2jfvA01 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.63 54.0 4.19e-01 100.0% 63.1%
7ntgA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.63 55.0 4.10e-01 100.0% 72.3%
3ojcA01 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.63 53.0 4.54e-01 100.0% 93.2%
3s7zA01 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.63 53.0 4.44e-01 100.0% 87.9%
2dx7A01 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.63 53.0 4.50e-01 100.0% 91.6%
2f8lA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 52.0 3.66e-01 98.5% 84.2%
3i3wA03 3.40.120.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 › Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 0.62 47.0 4.45e-01 83.3% 70.7%
3dnfA02 3.40.50.11270 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.62 48.0 4.56e-01 89.4% 74.7%
1ig3A02 3.40.50.10240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin pyrophosphokinase, catalytic domain 0.61 48.0 3.86e-01 90.9% 94.6%
2h5gB02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.60 52.0 4.08e-01 100.0% 95.9%
3r1iB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.60 51.0 3.56e-01 100.0% 85.4%
4jbeA02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.59 50.0 4.04e-01 100.0% 98.6%
1vq2A00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.58 44.0 3.33e-01 83.3% 88.4%
3frhA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 45.0 3.45e-01 93.9% 69.9%
1fmcA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 48.0 3.33e-01 100.0% 85.5%
2gdqA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.57 43.0 2.95e-01 84.8% 74.4%
2gm3A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.56 44.0 3.53e-01 92.4% 90.8%
2yfqB03 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 45.0 3.67e-01 95.5% 81.4%
3dlcA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 43.0 3.16e-01 92.4% 37.0%
2vz9A05 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 45.0 3.14e-01 98.5% 60.0%
4obxA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 46.0 3.17e-01 95.5% 80.9%
2r6zA01 3.40.1630.10 Alpha Beta › 3-Layer(aba) Sandwich › S-adenosyl-L-methionine-dependent methyltransferases › YhiQ-like domain 0.54 39.0 4.13e-01 92.4% 98.1%
5je6A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 42.0 2.92e-01 100.0% 25.3%
1zymA01 3.50.30.10 Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › Phosphohistidine domain 0.52 45.0 3.74e-01 100.0% 61.2%
1j0aA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 45.0 3.94e-01 100.0% 64.4%
3t05A04 3.50.30.10 Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › Phosphohistidine domain 0.51 45.0 3.83e-01 100.0% 65.5%
ECOD (99)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3963151 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.91 85.0 8.08e-01 100.0% 90.7%
3714816 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.90 84.0 7.20e-01 100.0% 72.0%
3904888 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.89 83.0 7.71e-01 100.0% 83.7%
3537238 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.87 80.0 6.76e-01 100.0% 71.4%
3592941 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.87 80.0 7.29e-01 100.0% 82.4%
4199854 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.87 81.0 7.54e-01 100.0% 91.3%
3230060 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.87 80.0 7.13e-01 100.0% 74.4%
3252479 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.86 79.0 7.19e-01 100.0% 83.5%
3259607 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.85 78.0 6.87e-01 100.0% 70.5%
3616608 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.85 78.0 6.68e-01 100.0% 68.0%
3588273 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.85 78.0 6.71e-01 100.0% 82.8%
3607887 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.85 76.0 6.01e-01 100.0% 50.0%
4001966 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.84 78.0 6.35e-01 100.0% 60.9%
3380599 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.84 76.0 6.71e-01 100.0% 72.6%
4024972 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.84 77.0 6.87e-01 100.0% 91.1%
3233287 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.84 77.0 6.75e-01 100.0% 71.6%
3990358 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.84 77.0 6.12e-01 100.0% 64.0%
4633934 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.84 77.0 7.29e-01 100.0% 87.2%
4520163 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.84 77.0 6.95e-01 100.0% 78.4%
3735484 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.84 77.0 6.75e-01 100.0% 71.6%
4050580 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.84 76.0 7.28e-01 100.0% 93.3%
4151620 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.84 77.0 6.87e-01 100.0% 75.6%
3925665 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.83 77.0 6.58e-01 100.0% 68.0%
4015594 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.83 76.0 6.25e-01 100.0% 60.0%
3791803 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.83 77.0 6.18e-01 100.0% 55.0%
3506892 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.83 76.0 6.69e-01 100.0% 70.5%
3401281 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.83 76.0 6.65e-01 100.0% 70.5%
3616609 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.83 76.0 6.04e-01 100.0% 53.6%
3623593 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.83 75.0 5.82e-01 100.0% 47.9%
3743319 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.83 74.0 6.46e-01 100.0% 74.0%
3708676 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.83 76.0 6.94e-01 100.0% 78.8%
4091629 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.83 76.0 7.09e-01 100.0% 85.0%
3793937 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.83 75.0 6.46e-01 100.0% 69.0%
3366583 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.83 75.0 6.35e-01 100.0% 64.8%
3185673 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.82 74.0 5.97e-01 100.0% 55.2%
3772733 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.82 75.0 5.92e-01 100.0% 50.8%
4049938 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.82 75.0 7.15e-01 100.0% 89.3%
3573818 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.82 75.0 5.89e-01 100.0% 51.5%
3953500 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.82 73.0 6.16e-01 100.0% 62.7%
3694717 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.82 74.0 6.66e-01 100.0% 76.7%
3270246 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.81 74.0 6.63e-01 100.0% 75.6%
4460512 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.81 74.0 6.95e-01 100.0% 86.3%
3210518 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.81 73.0 6.46e-01 100.0% 72.6%
3447755 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.81 73.0 5.80e-01 100.0% 53.1%
3260908 7568.1.1.6 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › RTT107_BRCT_5 0.81 74.0 6.26e-01 100.0% 63.8%
3730526 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.81 74.0 6.63e-01 100.0% 76.7%
3742190 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.81 74.0 6.37e-01 100.0% 73.0%
3278734 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.81 74.0 6.69e-01 100.0% 85.2%
3897282 7568.1.1.4 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT_2 0.81 71.0 6.53e-01 100.0% 75.3%
3739927 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.81 74.0 6.06e-01 100.0% 58.3%
4129749 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.81 73.0 6.86e-01 100.0% 85.0%
3475259 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.81 73.0 6.22e-01 100.0% 70.5%
3183356 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.81 73.0 5.92e-01 100.0% 58.3%
3928785 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.80 72.0 6.33e-01 100.0% 68.4%
3701657 7568.1.1.4 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT_2 0.80 73.0 6.57e-01 100.0% 74.4%
3429241 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.80 72.0 6.17e-01 100.0% 65.7%
4589655 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.80 73.0 6.86e-01 100.0% 83.7%
3607749 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.80 73.0 5.65e-01 100.0% 63.6%
3730516 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.80 72.0 6.38e-01 100.0% 71.6%
3436451 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.80 72.0 6.04e-01 100.0% 64.5%
3697099 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.80 71.0 5.92e-01 100.0% 60.0%
3494414 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.80 72.0 6.22e-01 100.0% 80.0%
3258560 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.80 72.0 6.32e-01 100.0% 73.7%
4260626 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.80 73.0 6.40e-01 100.0% 71.6%
4136176 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.79 72.0 6.63e-01 100.0% 80.0%
3614652 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.79 72.0 6.00e-01 100.0% 60.9%
3410319 7568.1.1.6 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › RTT107_BRCT_5 0.79 71.0 5.83e-01 100.0% 56.5%
3643441 7568.1.1.2 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › PTCB-BRCT 0.79 71.0 6.37e-01 100.0% 74.4%
3314116 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.79 70.0 6.34e-01 100.0% 75.6%
3834258 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.79 70.0 6.02e-01 100.0% 66.7%
3456976 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.78 70.0 6.30e-01 100.0% 75.6%
3301912 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.78 63.0 6.04e-01 89.4% 76.0%
4957650 2003.1.8.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › MurCD/PglD N-terminal domain-like 0.78 64.0 5.70e-01 87.9% 94.4%
4307693 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.78 70.0 6.76e-01 100.0% 90.7%
3443378 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.78 71.0 6.11e-01 100.0% 69.0%
3781702 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.78 69.0 6.03e-01 100.0% 69.0%
4241343 2007.2.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Phosphotyrosine protein phosphatases I-like › PTPase 0.78 70.0 6.57e-01 100.0% 92.5%
3263760 7568.1.1.4 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT_2 0.77 68.0 5.97e-01 100.0% 69.0%
3400469 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.77 68.0 6.18e-01 100.0% 73.3%
143537 7568.1.1.4 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT_2 0.77 68.0 5.94e-01 100.0% 69.3%
3515668 7568.1.1.4 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT_2 0.76 67.0 5.99e-01 100.0% 78.9%
3993706 2003.1.10.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.75 59.0 5.71e-01 87.9% 74.7%
2523980 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.75 67.0 5.18e-01 100.0% 52.1%
3222305 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.75 67.0 6.03e-01 100.0% 84.4%
3527792 2003.1.10.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.75 58.0 5.12e-01 86.4% 57.9%
3646136 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.75 60.0 5.75e-01 87.9% 84.0%
3858741 2003.1.10.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.74 56.0 6.00e-01 86.4% 96.4%
4620379 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.73 65.0 4.89e-01 98.5% 74.1%
3513740 7568.1.1.1 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT 0.73 65.0 5.99e-01 100.0% 78.8%
3586100 206.1.3.12 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL 0.71 63.0 3.76e-01 100.0% 70.8%
2082099 2006.1.1.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.70 60.0 5.04e-01 97.0% 84.3%
3346778 2003.1.1.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N 0.70 62.0 4.37e-01 100.0% 56.7%
3404479 2003.1.10.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.70 55.0 5.77e-01 86.4% 98.3%
3390461 206.1.3.12 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL 0.69 62.0 3.82e-01 100.0% 86.5%
3272160 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.69 60.0 5.50e-01 100.0% 76.7%
4166763 7603.1.1.3 ↗ a/b three-layered sandwiches › Immunomodulating metalloprotease IMPa N-terminal domain › Immunomodulating metalloprotease IMPa N-terminal domain › Immunomodulating metalloprotease IMPa N-terminal domain › PF27016 0.67 54.0 3.84e-01 90.9% 29.0%
3730454 2007.1.5.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › Asp_Glu_race 0.63 53.0 4.49e-01 97.0% 95.7%
4315643 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.62 52.0 4.02e-01 98.5% 70.9%
4044974 2007.1.5.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like 0.55 47.0 3.65e-01 98.5% 83.1%
D3 medium residues 103-140_260-320
PDB
Domain cluster: rep: ON649702__UVF62572.1__X__00095__D231-262_382-434
D4 medium residues 141-259
PDB
Domain cluster: rep: DNA_polymerase_X_NAD-dependent_DNA_ligase_fusion_protein__YP_009173744__Chrysochromulina_ericina_virus__455364__D566-656
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01653.24 best DNA_ligase_aden 29.0 1.10e-06 100.0% 31.2%
D5 medium residues 321-412
PDB
Domain cluster: rep: LC680885.1__BDE75744.1__X__00206__D318-424
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03120.23 best OB_DNA_ligase 50.0 3.20e-13 84.8% 94.9%
D6 medium residues 430-440_479-578
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1dgsA06 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.75 53.0 5.98e-01 72.1% 98.8%
2fq3A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 39.0 4.40e-01 72.1% 97.6%
2dgzA01 1.10.150.80 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain 0.57 40.0 4.41e-01 74.8% 93.3%
4is7A02 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.56 36.0 4.24e-01 76.6% 98.6%
2rrdA00 1.10.150.80 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain 0.56 38.0 3.98e-01 71.2% 77.2%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.55 33.0 3.82e-01 74.8% 80.7%
1g4uS01 1.20.120.260 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Virulence factor YopE uncharacterised domain 0.54 33.0 3.23e-01 89.2% 52.8%
2keyA00 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.54 42.0 4.23e-01 83.8% 84.8%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 37.0 3.84e-01 72.1% 92.2%
4xviA01 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.53 39.0 3.56e-01 75.7% 86.1%
3fblA00 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 29.0 3.31e-01 79.3% 75.6%
5c9iA02 1.10.1400.10 Mainly Alpha › Orthogonal Bundle › Penicillin amidase (Acylase) alpha subunit, N-terminal domain › Aminohydrolase, alpha-helical knob region 0.51 31.0 2.77e-01 72.1% 43.0%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4289465 102.1.1.79 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DNA_ligase_ZBD+HHH_2+HHH_5 0.78 67.0 5.51e-01 92.8% 75.4%
4179566 102.1.1.24 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_2 0.78 65.0 5.47e-01 90.1% 82.7%
4081948 102.1.1.10 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DNA_ligase_ZBD,HHH_2 0.77 67.0 5.43e-01 92.8% 76.5%
4058845 102.1.1.10 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DNA_ligase_ZBD,HHH_2 0.77 64.0 5.20e-01 89.2% 79.0%
4038838 102.1.1.104 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH, HHH_2, HHH_5 0.77 63.0 5.44e-01 87.4% 81.2%
4668711 102.1.1.10 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DNA_ligase_ZBD,HHH_2 0.77 69.0 5.69e-01 97.3% 81.6%
4110087 102.1.1.79 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DNA_ligase_ZBD+HHH_2+HHH_5 0.76 65.0 5.42e-01 91.0% 80.0%
None — 0.76 63.0 5.42e-01 90.1% 80.6%
4679202 102.1.1.79 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DNA_ligase_ZBD+HHH_2+HHH_5 0.75 67.0 5.60e-01 98.2% 81.6%
4128729 102.1.1.96 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH, DNA_ligase_ZBD, HHH_2, HHH_5 0.75 64.0 5.44e-01 92.8% 80.6%
4128948 102.1.1.81 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_2+HHH_5 0.74 64.0 5.49e-01 93.7% 80.0%
4302460 102.1.1.79 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DNA_ligase_ZBD+HHH_2+HHH_5 0.74 62.0 5.33e-01 90.1% 81.8%
4380943 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.69 57.0 5.00e-01 88.3% 82.5%
3569105 102.1.1.2 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HRDC 0.59 43.0 4.61e-01 76.6% 90.5%
3608193 4156.1.1.2 ↗ alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C 0.57 47.0 3.84e-01 89.2% 69.0%
3209343 4156.1.1.4 ↗ alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C 0.53 44.0 3.99e-01 93.7% 81.3%