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NP_542573.1

Arc-Vir

NC_003345__NP_542573.1__HrrHF2-485__00092

Identity

Accession:
NC_003345 ↗
Protein ID:
NP_542573.1 ↗
Kingdom:
archaea

Quality

76.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 4-40
PDB
Domain cluster: representative
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2wxwA02 3.30.497.10 Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 0.76 63.0 3.99e-01 100.0% 36.7%
5m38C00 3.30.1330.60 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › OmpA-like domain 0.73 60.0 4.39e-01 100.0% 66.7%
1z3eA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.72 59.0 4.22e-01 97.3% 83.2%
1k0mA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.71 59.0 4.55e-01 100.0% 71.7%
3q6oA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.70 57.0 4.03e-01 100.0% 51.5%
3oonA00 3.30.1330.60 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › OmpA-like domain 0.69 54.0 4.04e-01 100.0% 57.5%
1p9lA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.67 54.0 4.08e-01 100.0% 68.2%
3qs2A00 2.60.40.3290 Mainly Beta › Sandwich › Immunoglobulin-like › Fimbrial protein EcpA 0.66 53.0 3.56e-01 100.0% 89.6%
1vm6A02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.65 52.0 4.23e-01 100.0% 57.8%
5zfgA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.65 50.0 4.22e-01 100.0% 76.2%
3a43A01 3.30.2320.50 Alpha Beta › 2-Layer Sandwich › hypothetical protein PF0899 fold › 0.64 53.0 4.31e-01 100.0% 64.6%
3r4vA01 3.40.50.1440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain 0.64 52.0 3.15e-01 100.0% 15.1%
3zbqA00 3.40.50.1440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain 0.63 50.0 3.00e-01 97.3% 13.0%
2hraA01 3.40.30.70 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › 0.63 50.0 3.95e-01 94.6% 56.2%
1senA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.63 52.0 3.64e-01 100.0% 47.8%
5a4uA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.63 50.0 4.04e-01 100.0% 70.9%
1dihA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.63 50.0 3.77e-01 100.0% 67.6%
1ef1A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.63 37.0 2.90e-01 100.0% 22.8%
2rflH00 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.62 50.0 3.44e-01 100.0% 90.4%
3qavA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.62 47.0 4.00e-01 100.0% 77.2%
5tshA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 41.0 2.47e-01 70.3% 18.1%
2ybdA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.57 39.0 2.70e-01 73.0% 32.6%
2gzaB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 46.0 2.95e-01 100.0% 77.9%
3ewmA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.56 43.0 2.68e-01 100.0% 47.0%
4lq6A00 3.40.630.40 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn-dependent exopeptidases 0.55 39.0 2.69e-01 100.0% 35.2%
2fazA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.55 37.0 3.02e-01 73.0% 96.1%
4mdcD01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.55 38.0 3.11e-01 94.6% 52.7%
3ry7A00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.55 43.0 2.67e-01 100.0% 48.2%
4a4yA01 2.60.200.50 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.54 38.0 3.21e-01 100.0% 37.8%
4a8jB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 45.0 2.82e-01 100.0% 32.3%
1ujcA00 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.52 36.0 2.74e-01 100.0% 88.5%
1wspA00 2.40.240.130 Mainly Beta › Beta Barrel › Ribosomal Protein L25; Chain P › 0.52 35.0 2.73e-01 100.0% 24.1%
7pyvC02 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.51 33.0 2.76e-01 100.0% 27.1%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3801941 1.1.8.0 beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain 0.78 67.0 4.74e-01 100.0% 61.7%
3268145 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.73 61.0 4.48e-01 100.0% 46.4%
4024415 10.32.1.0 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.73 61.0 3.99e-01 100.0% 89.7%
1258823 10.18.1.2 beta sandwiches › jelly-roll › VPA0735-like › VPA0735-like › DUF1254 0.71 57.0 3.67e-01 89.2% 34.7%
5056874 298.4.1.0 a+b two layers › FwdE/GAPDH domain-like › V-type ATPase subunit E › V-type ATPase subunit E 0.71 56.0 4.20e-01 100.0% 34.9%
3213645 267.1.1.0 a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.70 38.0 2.28e-01 100.0% 7.6%
3956155 3268.1.1.1 a+b two layers › N-terminal domain in xanthine dehydrogenase › N-terminal domain in xanthine dehydrogenase › N-terminal domain in xanthine dehydrogenase › XdhC_CoxI 0.69 56.0 4.17e-01 100.0% 34.5%
3243185 4059.1.1.0 a+b complex topology › Serpins › Serpins › Serpins 0.68 55.0 3.19e-01 100.0% 23.9%
4015851 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.68 54.0 3.71e-01 100.0% 29.4%
5011378 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.68 54.0 4.56e-01 97.3% 67.1%
3700956 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.68 55.0 3.96e-01 100.0% 56.0%
3646203 301.13.1.4 a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain › Tubulin 0.68 52.0 4.15e-01 91.9% 71.8%
3291339 2485.1.1.56 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Rng_hyd_C 0.67 55.0 4.19e-01 100.0% 50.0%
4415244 2485.1.1.56 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Rng_hyd_C 0.67 56.0 4.23e-01 100.0% 42.0%
4268188 298.1.1.9 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › DapB_C 0.66 53.0 3.95e-01 100.0% 58.3%
4443992 298.1.1.9 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › DapB_C 0.66 53.0 4.04e-01 100.0% 61.9%
4456886 314.1.1.12 a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › LplA-B_cat 0.65 52.0 3.32e-01 94.6% 17.1%
4646646 301.1.1.0 a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like 0.65 52.0 4.04e-01 97.3% 50.5%
3737955 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 51.0 3.42e-01 100.0% 23.2%
1147865 301.6.1.5 a+b three layers › Bacillus chorismate mutase-like › Tubulin C-terminal domain-like › Tubulin C-terminal domain-like › TubZ_C_2 0.64 51.0 3.67e-01 100.0% 32.4%
4172925 298.1.1.9 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › DapB_C 0.64 51.0 4.09e-01 100.0% 61.1%
4955983 7523.1.1.0 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.64 53.0 3.03e-01 97.3% 15.9%
869080 301.6.1.5 a+b three layers › Bacillus chorismate mutase-like › Tubulin C-terminal domain-like › Tubulin C-terminal domain-like › TubZ_C_2 0.64 50.0 3.58e-01 97.3% 55.0%
5018248 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.62 53.0 3.32e-01 100.0% 39.5%
3351153 2485.1.1.40 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › GST_N_3 0.62 49.0 3.93e-01 100.0% 74.4%
3174289 310.3.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.62 49.0 3.90e-01 97.3% 46.7%
3836457 4.1.1.20 beta barrels › SH3 › SH3 › SH3 › BAH 0.62 48.0 3.24e-01 89.2% 39.3%
4012811 314.1.1.0 a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases 0.61 46.0 2.81e-01 100.0% 80.3%
5062584 3008.1.1.2 a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DUF5915 0.57 44.0 3.63e-01 100.0% 67.1%
3198846 2003.1.1.53 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NmrA 0.56 46.0 2.75e-01 100.0% 13.0%
4458848 2003.1.1.37 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 2-Hacid_dh_C 0.55 40.0 2.62e-01 81.1% 24.9%
3511359 4038.1.1.0 alpha bundles › Alpha-helical domain in upper collar protein › Alpha-helical domain in upper collar protein › Alpha-helical domain in upper collar protein 0.54 40.0 2.49e-01 100.0% 11.7%
3702777 2485.1.1.18 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › SH3BGR 0.53 37.0 3.06e-01 100.0% 90.0%
3772155 73.1.1.6 beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain › IRF-3 0.53 39.0 2.58e-01 100.0% 26.7%
3644593 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 39.0 2.67e-01 94.6% 75.2%
D2 medium residues 51-114
PDB
Domain cluster: representative
CATH (59)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.87 64.0 4.92e-01 76.6% 46.6%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.86 64.0 5.96e-01 78.1% 64.1%
2yevA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.84 60.0 5.72e-01 78.1% 64.9%
3craA02 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.83 62.0 4.83e-01 78.1% 39.8%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.83 62.0 4.23e-01 79.7% 23.9%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.82 62.0 5.07e-01 79.7% 49.1%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 60.0 5.00e-01 76.6% 60.6%
3itfA00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.81 57.0 4.69e-01 78.1% 42.3%
5fhiA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.81 60.0 4.56e-01 78.1% 39.6%
6t0bc01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.80 61.0 5.65e-01 79.7% 67.9%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.79 58.0 5.63e-01 78.1% 90.1%
2guzB00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.79 55.0 5.55e-01 73.4% 73.8%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.79 71.0 5.72e-01 100.0% 55.5%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.77 57.0 6.25e-01 79.7% 98.0%
1wp1B01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.77 57.0 3.52e-01 79.7% 42.9%
3l39A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.74 65.0 4.63e-01 100.0% 44.0%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 66.0 4.35e-01 100.0% 81.7%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.74 65.0 5.36e-01 96.9% 59.8%
2qsbA00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.73 64.0 5.78e-01 100.0% 72.9%
7p5hB03 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.73 60.0 5.35e-01 90.6% 66.3%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.71 60.0 4.89e-01 95.3% 66.4%
2f2gA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.71 63.0 4.35e-01 100.0% 63.3%
1vljA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.70 61.0 4.20e-01 96.9% 32.2%
1s5jA04 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.70 51.0 5.27e-01 78.1% 82.0%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.69 60.0 4.98e-01 100.0% 66.7%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 59.0 4.25e-01 100.0% 82.6%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.68 60.0 3.94e-01 100.0% 77.1%
3rf7A02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.68 57.0 4.22e-01 95.3% 36.6%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.68 56.0 4.16e-01 96.9% 85.3%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.68 58.0 4.71e-01 95.3% 69.7%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 56.0 4.03e-01 100.0% 37.3%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.67 49.0 5.02e-01 79.7% 86.9%
6q9jB02 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.67 52.0 4.77e-01 89.1% 63.6%
8b9zK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 49.0 4.40e-01 79.7% 64.8%
2mabA00 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.66 46.0 3.91e-01 73.4% 46.8%
7k0yA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.66 46.0 2.74e-01 73.4% 10.1%
1y6xA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.66 47.0 4.32e-01 76.6% 56.3%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.65 56.0 3.46e-01 100.0% 72.3%
4cy8A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.65 47.0 3.22e-01 79.7% 20.2%
1tfkB00 1.20.120.650 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Colicin D 0.65 54.0 5.00e-01 95.3% 80.2%
3o39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 48.0 4.23e-01 79.7% 72.9%
1lj2A00 1.20.5.970 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Nonstructural RNA-binding protein 0.64 49.0 4.28e-01 100.0% 52.8%
3ez0C00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 52.0 3.72e-01 95.3% 95.2%
2v6eA01 1.10.287.3180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 44.0 4.30e-01 81.2% 65.3%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.62 52.0 4.28e-01 98.4% 58.4%
4fjvA02 1.20.1300.20 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 0.62 52.0 4.13e-01 100.0% 75.0%
3knwB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 52.0 3.75e-01 93.8% 90.4%
4h8aB01 1.10.1530.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel 0.60 45.0 4.67e-01 90.6% 88.3%
2g3bA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 50.0 3.67e-01 96.9% 51.3%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.59 49.0 4.10e-01 98.4% 59.3%
3i2fA02 1.10.3020.10 Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) 0.57 45.0 4.05e-01 95.3% 61.1%
3uarA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 40.0 3.46e-01 73.4% 43.9%
2qgaB01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.56 48.0 4.06e-01 100.0% 76.3%
3dfzA02 1.10.8.610 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › SirC, precorrin-2 dehydrogenase, C-terminal helical domain-like 0.56 43.0 4.11e-01 96.9% 73.0%
4nqwA01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.54 39.0 3.60e-01 92.2% 58.3%
2kbwA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.54 45.0 3.48e-01 96.9% 70.6%
2ijqA00 1.10.3450.10 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like 0.54 42.0 3.35e-01 90.6% 66.9%
2iw3A02 1.20.1390.20 Mainly Alpha › Up-down Bundle › PWI domain › 0.53 44.0 4.00e-01 93.8% 70.0%
5ts9B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.51 44.0 3.32e-01 98.4% 61.5%
ECOD (75)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3502849 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.89 67.0 5.25e-01 78.1% 41.7%
3631825 109.4.1.1407 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › STAG, SCD, HEAT_SCC3-SA 0.89 66.0 3.55e-01 78.1% 4.7%
5068187 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.88 59.0 5.57e-01 71.9% 59.5%
4569741 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.88 66.0 5.28e-01 78.1% 43.5%
3408508 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.88 66.0 6.04e-01 78.1% 66.3%
4132296 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.88 65.0 6.77e-01 78.1% 88.3%
4378877 3711.1.1.20 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DUF444 0.87 65.0 6.11e-01 78.1% 66.7%
3239510 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.87 65.0 5.56e-01 78.1% 52.6%
4096596 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.87 66.0 3.85e-01 79.7% 11.7%
3905660 603.1.1.164 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SERTA 0.86 64.0 6.45e-01 78.1% 81.5%
4406266 632.7.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.86 62.0 5.45e-01 75.0% 53.3%
4940281 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.86 67.0 6.67e-01 81.2% 87.7%
3942662 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.86 65.0 5.60e-01 79.7% 55.8%
3909017 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.85 64.0 5.59e-01 78.1% 74.4%
3721457 3291.1.1.134 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › MPC 0.85 63.0 5.29e-01 76.6% 49.0%
3631342 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.85 65.0 5.36e-01 79.7% 59.0%
3205582 605.8.1.2 alpha duplicates or obligate multimers › ROP-like › BAS1536-like › BAS1536-like › PF27894 0.84 61.0 6.07e-01 76.6% 73.8%
4945538 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.84 62.0 6.06e-01 78.1% 75.7%
4000262 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.84 62.0 5.48e-01 78.1% 58.9%
3790121 603.1.1.114 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HR1 0.84 62.0 5.27e-01 78.1% 53.0%
3988974 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.84 62.0 5.10e-01 78.1% 46.4%
3189247 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.83 63.0 4.15e-01 79.7% 21.8%
3558280 603.1.1.114 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HR1 0.83 62.0 5.34e-01 78.1% 55.8%
4156067 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.83 62.0 5.07e-01 78.1% 48.2%
3621635 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.83 60.0 4.51e-01 78.1% 32.7%
3977695 3711.1.1.1 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ 0.82 58.0 4.62e-01 78.1% 39.2%
3267886 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.82 62.0 3.98e-01 78.1% 19.2%
3596712 633.1.1.0 alpha bundles › Bromodomain-like › Bromodomain › Bromodomain 0.82 62.0 4.60e-01 79.7% 54.0%
3737161 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.82 61.0 4.99e-01 78.1% 54.5%
3963743 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.82 61.0 5.14e-01 79.7% 48.6%
4156290 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.81 55.0 6.21e-01 73.4% 100.0%
3243599 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.81 60.0 4.85e-01 78.1% 47.0%
3680604 246.3.1.17 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › PF27823 0.81 61.0 3.87e-01 79.7% 18.6%
3656716 3755.3.1.498 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF31016 0.81 61.0 4.58e-01 79.7% 75.9%
3271303 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.81 72.0 4.72e-01 100.0% 70.6%
3762595 604.7.1.13 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › HR1 0.80 59.0 5.26e-01 78.1% 55.6%
4101843 632.7.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.80 57.0 4.81e-01 78.1% 45.7%
3730497 6155.1.1.4 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC 0.80 59.0 4.87e-01 78.1% 46.4%
3203534 192.15.1.139 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Cation_efflux 0.80 71.0 5.08e-01 96.9% 56.6%
3235839 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.78 58.0 4.21e-01 79.7% 29.1%
3719637 192.12.1.0 alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM 0.78 57.0 5.08e-01 78.1% 58.9%
3215718 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.78 57.0 5.30e-01 78.1% 62.5%
3477880 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.77 57.0 3.68e-01 79.7% 18.3%
3475661 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.77 68.0 5.21e-01 100.0% 53.1%
3255232 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.77 69.0 4.58e-01 100.0% 70.0%
3170491 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.77 68.0 4.68e-01 100.0% 81.8%
5018556 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.75 65.0 5.42e-01 98.4% 80.9%
3268765 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.75 67.0 4.48e-01 100.0% 74.6%
2507423 632.2.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › FIVAR 0.74 54.0 5.10e-01 78.1% 65.4%
3488978 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.74 54.0 3.48e-01 78.1% 18.3%
4862444 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.74 65.0 5.08e-01 100.0% 64.0%
3410818 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.74 63.0 5.15e-01 98.4% 66.4%
3595656 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.73 64.0 5.07e-01 100.0% 66.7%
3213281 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.73 63.0 4.12e-01 95.3% 81.1%
3519973 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.72 54.0 3.61e-01 79.7% 57.6%
3720652 4177.1.1.5 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.72 62.0 4.22e-01 100.0% 74.9%
5053481 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.72 62.0 5.69e-01 98.4% 72.9%
3919688 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.70 61.0 4.16e-01 100.0% 69.2%
3437287 5086.1.1.199 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PF31016 0.70 52.0 3.84e-01 81.2% 30.3%
1291200 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.69 59.0 3.81e-01 95.3% 76.6%
3236352 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.69 58.0 4.22e-01 96.9% 85.4%
3358852 3755.4.1.62 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF31016 0.69 51.0 3.87e-01 79.7% 47.1%
3423702 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.69 58.0 4.42e-01 98.4% 71.2%
3576467 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.68 59.0 3.84e-01 100.0% 72.5%
3691337 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.68 56.0 4.00e-01 96.9% 77.7%
3213527 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.67 57.0 3.76e-01 96.9% 76.8%
3707613 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.66 48.0 3.26e-01 79.7% 21.2%
5001960 632.2.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › FIVAR 0.66 54.0 5.20e-01 93.8% 86.7%
3232199 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.65 55.0 3.71e-01 100.0% 74.4%
3908810 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.65 53.0 3.52e-01 95.3% 73.6%
3289802 284.1.1.0 a+b two layers › FKBP-like › FKBP-like › FKBP-like 0.61 51.0 3.01e-01 95.3% 34.0%
3701328 109.4.1.1362 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG5_C 0.61 43.0 3.44e-01 73.4% 38.5%
5021020 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.60 48.0 4.33e-01 98.4% 63.3%
4597483 5058.1.1.1 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st 0.59 49.0 4.05e-01 95.3% 64.2%
4884093 7579.1.1.17 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S15 0.58 46.0 2.95e-01 95.3% 16.5%