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NC_004735.1__NP_835679.1__Rm378p092__00092

Bact-Vir

NC_004735.1__NP_835679.1__Rm378p092__00092

Identity

Accession:
NC_004735 ↗
Kingdom:
phage

Quality

85.3 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Rhodothermus_phage_RM378

TaxID: 148943

Cluster

View cluster (8 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 339-478
PDB
Domain cluster: representative
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qexA06 3.40.1820.10 Alpha Beta › 3-Layer(aba) Sandwich › Ribonuclease H-like motif › DnaQ-like 3'-5' exonuclease 0.73 47.0 5.73e-01 100.0% 98.9%
3iayA07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.71 36.0 3.58e-01 100.0% 45.4%
3b0pA02 1.20.120.1460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.59 29.0 3.78e-01 80.0% 85.3%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5037637 101.35.1.0 ↗ alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.74 30.0 4.79e-01 85.0% 98.2%
2036845 3546.1.1.1 ↗ alpha arrays › Peroxisomal biogenesis factor 14 N-terminal domain › Peroxisomal biogenesis factor 14 N-terminal domain › Peroxisomal biogenesis factor 14 N-terminal domain › Pex14_N 0.65 31.0 4.23e-01 77.1% 90.0%
4884450 4969.1.1.1 ↗ alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.63 36.0 3.91e-01 100.0% 66.1%
1122403 3546.1.1.1 ↗ alpha arrays › Peroxisomal biogenesis factor 14 N-terminal domain › Peroxisomal biogenesis factor 14 N-terminal domain › Peroxisomal biogenesis factor 14 N-terminal domain › Pex14_N 0.60 29.0 4.11e-01 86.4% 95.7%
4935886 4969.1.1.0 ↗ alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.54 33.0 3.07e-01 100.0% 46.4%
3448927 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 40.0 4.39e-01 90.7% 95.7%
3382601 109.4.1.27 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › W2 0.51 39.0 3.61e-01 86.4% 63.4%
D2 medium residues 1-33_185-289
PDB
Domain cluster: representative
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qexA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.90 86.0 6.85e-01 98.6% 98.8%
1q8iA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.89 84.0 7.14e-01 98.6% 76.1%
2gv9B04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.84 74.0 6.38e-01 91.3% 99.0%
4fxdA05 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.79 62.0 6.75e-01 91.3% 95.7%
2py5A02 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.77 74.0 6.64e-01 100.0% 83.8%
1d5aA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.76 61.0 5.70e-01 82.6% 93.9%
1s5jA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.75 68.0 6.46e-01 94.2% 98.1%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.72 51.0 5.25e-01 71.7% 86.2%
2w01B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.71 56.0 5.00e-01 84.1% 88.8%
3r5gA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.71 57.0 5.07e-01 85.5% 71.8%
1zpwX00 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 39.0 4.86e-01 84.8% 90.2%
1azsA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.70 56.0 5.04e-01 85.5% 70.0%
4kgmA00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.69 56.0 4.69e-01 85.5% 85.7%
5oyhD00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.69 56.0 5.04e-01 85.5% 71.9%
1vk8A00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 45.0 5.37e-01 84.1% 100.0%
7uinD01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.68 55.0 5.18e-01 86.2% 90.4%
1f5aA01 3.30.70.590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain 0.65 44.0 4.97e-01 70.3% 100.0%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.64 51.0 4.25e-01 84.8% 90.4%
6zxbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 54.0 5.34e-01 89.9% 94.4%
4ol8A01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 49.0 5.00e-01 94.9% 83.7%
3hdiA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.63 49.0 4.34e-01 81.9% 88.9%
2i8eA01 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 35.0 4.51e-01 78.3% 100.0%
3ui3A02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 42.0 4.80e-01 74.6% 94.9%
4makB00 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 32.0 4.07e-01 79.0% 86.8%
2fgeA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.62 49.0 4.07e-01 83.3% 84.5%
4hkqA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 52.0 5.16e-01 98.6% 86.8%
3gv5B01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 48.0 4.90e-01 79.7% 100.0%
4wp3C00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.61 51.0 4.60e-01 89.1% 69.5%
3tviA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.61 49.0 4.67e-01 84.8% 86.2%
3oq2A00 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 42.0 4.80e-01 76.8% 98.0%
1x9mA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 52.0 4.76e-01 94.9% 93.3%
2r7rA04 3.30.70.2480 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 48.0 4.65e-01 93.5% 77.7%
3pm9A03 3.30.70.2190 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 43.0 4.54e-01 85.5% 93.4%
4kr6A01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.53 43.0 4.04e-01 87.0% 89.5%
2lxfA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 36.0 3.77e-01 79.0% 77.7%
3popA02 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.52 39.0 3.27e-01 84.8% 43.3%
2h5eA03 3.30.70.3280 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptide chain release factor 3, domain III 0.51 41.0 4.16e-01 87.0% 86.1%
1reoA01 3.90.660.10 Alpha Beta › Alpha-Beta Complex › Polyamine Oxidase; Chain A, domain 2 › 0.50 36.0 3.38e-01 75.4% 66.7%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4939489 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.91 87.0 7.53e-01 98.6% 96.4%
3968795 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 85.0 6.58e-01 98.6% 89.6%
5040510 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.85 82.0 6.53e-01 100.0% 99.2%
3597965 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.85 79.0 6.25e-01 95.7% 100.0%
5025209 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.85 81.0 6.53e-01 98.6% 97.9%
3684974 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.84 80.0 4.95e-01 98.6% 40.2%
5019480 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.84 80.0 4.85e-01 98.6% 37.2%
4997717 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.84 80.0 5.92e-01 99.3% 89.4%
3466667 2484.1.1.161 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.83 79.0 4.87e-01 97.8% 35.2%
4944522 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.83 78.0 6.23e-01 97.8% 99.2%
4276636 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.83 78.0 5.62e-01 97.1% 77.9%
5005286 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.83 79.0 5.85e-01 99.3% 90.8%
4981193 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.82 78.0 6.11e-01 97.8% 88.2%
5017083 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.82 77.0 5.98e-01 98.6% 88.5%
4942685 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.81 77.0 5.10e-01 99.3% 47.2%
4932480 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.81 77.0 6.37e-01 97.8% 99.5%
4958554 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.81 77.0 6.25e-01 98.6% 98.7%
4956224 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.81 78.0 6.29e-01 99.3% 94.5%
4243736 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.80 72.0 6.65e-01 100.0% 77.6%
4282509 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 75.0 4.79e-01 98.6% 32.6%
3582653 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.79 71.0 6.26e-01 100.0% 67.9%
4977369 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.78 73.0 5.81e-01 97.8% 89.6%
4978605 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.78 74.0 5.65e-01 100.0% 78.9%
4629010 304.48.1.24 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.77 69.0 5.77e-01 94.2% 87.1%
4461958 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.77 75.0 5.99e-01 100.0% 87.1%
3266689 304.48.1.24 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.77 68.0 5.39e-01 92.8% 88.1%
4100823 4970.1.1.1 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.77 72.0 5.77e-01 98.6% 86.4%
3206807 304.48.1.24 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.77 70.0 5.47e-01 95.7% 84.1%
4419306 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.77 70.0 5.92e-01 94.9% 94.8%
4022145 2484.1.1.153 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1744 0.77 69.0 4.38e-01 95.7% 34.7%
4982660 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.77 72.0 6.06e-01 98.6% 94.4%
3578106 304.48.1.24 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.77 72.0 5.57e-01 99.3% 87.3%
4182409 304.48.1.24 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.76 69.0 6.50e-01 95.7% 93.8%
5076614 2484.1.1.328 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B 0.75 70.0 4.39e-01 98.6% 36.3%
4629102 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.75 70.0 4.68e-01 100.0% 29.3%
3598488 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.74 59.0 5.59e-01 81.9% 100.0%
3613455 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.74 59.0 5.89e-01 82.6% 94.2%
4264107 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.74 71.0 5.29e-01 100.0% 74.7%
3591785 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 58.0 5.68e-01 83.3% 92.7%
3608339 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.72 57.0 5.80e-01 82.6% 99.3%
4365778 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.72 69.0 5.25e-01 100.0% 77.1%
3680878 304.48.1.17 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.72 68.0 5.03e-01 100.0% 79.7%
None — 0.71 57.0 4.64e-01 85.5% 65.1%
2803899 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.70 57.0 4.85e-01 86.2% 64.2%
3951840 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.70 57.0 4.72e-01 87.0% 60.8%
4123628 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.70 40.0 5.03e-01 84.8% 96.2%
None — 0.69 57.0 4.72e-01 88.4% 64.9%
3511287 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.69 55.0 4.61e-01 84.8% 61.3%
4983372 304.48.1.20 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1 0.68 56.0 4.50e-01 85.5% 86.4%
3279576 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.67 56.0 4.86e-01 87.7% 70.2%
3934934 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.67 56.0 4.61e-01 88.4% 61.6%
5069565 304.26.1.0 ↗ a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like 0.67 45.0 5.32e-01 84.8% 100.0%
3705667 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.66 53.0 4.53e-01 84.8% 63.3%
4153524 304.48.1.10 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.65 52.0 5.39e-01 82.6% 96.9%
4073171 304.120.1.11 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › UreE_C 0.65 42.0 4.89e-01 76.8% 93.7%
4246202 304.56.1.6 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › UreE_C 0.65 42.0 4.88e-01 76.8% 93.7%
4059719 304.9.1.61 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Thc1_RRM 0.65 37.0 4.68e-01 82.6% 100.0%
3703418 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 53.0 5.33e-01 87.7% 100.0%
4632150 304.56.1.0 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like 0.64 42.0 4.83e-01 76.8% 93.7%
3953647 304.26.1.1 ↗ a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Thiamine_BP 0.64 43.0 5.01e-01 84.1% 100.0%
3593319 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 51.0 4.66e-01 85.5% 87.0%
4016673 304.112.1.0 ↗ a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.63 41.0 4.92e-01 70.3% 100.0%
3211433 304.20.1.1 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP_RNA-bind 0.62 52.0 5.19e-01 88.4% 98.6%
1116853 304.56.1.2 ↗ a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.62 42.0 4.84e-01 74.6% 96.9%
5040616 304.128.1.0 ↗ a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB 0.62 43.0 4.91e-01 82.6% 97.0%
3931565 304.20.1.1 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP_RNA-bind 0.62 51.0 5.08e-01 87.0% 99.3%
3716499 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 49.0 4.18e-01 84.8% 74.2%
3600554 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 47.0 4.20e-01 81.2% 56.5%
3918163 304.20.1.1 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP_RNA-bind 0.61 50.0 5.07e-01 88.4% 100.0%
3699931 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.61 49.0 4.54e-01 87.0% 90.0%
3925602 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.60 54.0 4.41e-01 100.0% 83.8%
3427907 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.60 54.0 4.41e-01 100.0% 83.5%
3927691 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.60 54.0 4.44e-01 99.3% 86.0%
3571315 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.59 54.0 4.53e-01 100.0% 96.6%
3709693 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.59 47.0 4.29e-01 84.1% 82.7%
3643305 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.59 49.0 5.03e-01 89.9% 100.0%
3737895 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.59 53.0 4.34e-01 98.6% 85.6%
4659512 321.1.1.7 ↗ a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › GCS2 0.57 44.0 3.24e-01 81.2% 66.9%
3927365 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.56 51.0 4.21e-01 100.0% 71.0%
3483436 304.110.1.0 ↗ a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like 0.52 41.0 3.79e-01 84.8% 91.4%
1699308 304.6.1.3 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.52 40.0 3.24e-01 86.2% 40.3%
D3 medium residues 34-127
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4aimA03 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.67 37.0 4.17e-01 89.4% 70.4%
2cxaA01 3.30.70.3550 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Leucyl/phenylalanyl-tRNA-protein transferase, N-terminal domain 0.62 30.0 3.64e-01 87.2% 68.3%
2cxiA03 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.59 33.0 3.67e-01 89.4% 70.0%
3pcoB04 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.56 32.0 3.54e-01 88.3% 68.0%
4p72A04 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.56 33.0 3.56e-01 88.3% 68.4%
2mkhA02 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.55 34.0 3.45e-01 94.7% 60.8%
8egxA04 2.60.40.60 Mainly Beta › Sandwich › Immunoglobulin-like › Cadherins 0.55 31.0 3.05e-01 92.6% 49.5%
1b7yB01 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.54 29.0 3.25e-01 83.0% 65.7%
2kx2A00 3.30.780.30 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › 0.54 30.0 2.99e-01 90.4% 51.0%
3euhD01 1.10.10.2250 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.53 30.0 3.33e-01 81.9% 70.0%
4c9yA00 1.10.10.1890 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ska1 microtubule binding domain-like 0.53 31.0 2.88e-01 88.3% 42.3%
2xzn800 3.30.63.20 Alpha Beta › 2-Layer Sandwich › Guanylate Kinase phosphate binding domain › 0.51 29.0 3.01e-01 86.2% 53.8%
2zzzA02 3.30.63.10 Alpha Beta › 2-Layer Sandwich › Guanylate Kinase phosphate binding domain › Guanylate Kinase phosphate binding domain 0.50 28.0 3.29e-01 78.7% 83.3%
1v89A00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.50 34.0 3.17e-01 85.1% 55.1%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4351112 327.11.2.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.69 38.0 4.18e-01 89.4% 66.7%
5047775 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.64 35.0 3.72e-01 90.4% 58.8%
4170959 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.63 31.0 3.72e-01 81.9% 70.0%
4928313 327.11.2.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.62 38.0 3.19e-01 98.9% 35.2%
3182652 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.59 34.0 3.62e-01 87.2% 65.0%
3311334 310.1.1.2 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain › Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain › Arg_tRNA_synt_N 0.55 36.0 3.50e-01 97.9% 57.8%
3601429 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.54 32.0 3.10e-01 90.4% 49.1%
4011754 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.53 34.0 3.44e-01 89.4% 64.2%
3822416 101.1.2.7 ↗ alpha arrays › HTH › HTH › winged helix domain › HSF_DNA-bind 0.51 32.0 3.14e-01 90.4% 55.2%
5025686 101.1.2.135 ↗ alpha arrays › HTH › HTH › winged helix domain › MarR_2 0.51 30.0 3.37e-01 89.4% 75.7%
3917175 328.7.1.1 ↗ a+b two layers › IF3-like › Smr domain › Smr domain › Smr 0.51 29.0 2.80e-01 88.3% 45.1%
3782879 11.2.1.41 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2_TCB1 0.50 37.0 3.40e-01 78.7% 82.3%
D4 medium residues 128-184
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 34.2 1.80e-08 100.0% 13.2%
CATH (66)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fvmA06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.96 69.0 7.57e-01 75.4% 97.9%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.91 67.0 4.76e-01 77.2% 41.4%
2gv9A05 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.91 76.0 7.57e-01 89.5% 91.5%
1hr5A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.91 71.0 7.71e-01 82.5% 97.9%
1o9gA02 1.10.287.540 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.91 63.0 7.13e-01 71.9% 95.3%
3k59A06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.90 70.0 7.64e-01 94.7% 100.0%
2aw6A02 1.25.40.400 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.89 62.0 4.01e-01 71.9% 18.6%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.87 65.0 5.55e-01 78.9% 57.5%
2nr4A02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.86 60.0 6.04e-01 77.2% 72.4%
1aueB00 1.20.120.150 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › FKBP12-rapamycin binding domain 0.86 67.0 5.54e-01 82.5% 50.0%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.84 70.0 6.50e-01 89.5% 90.1%
7eu3E01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.84 70.0 6.05e-01 91.2% 65.5%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.83 71.0 5.36e-01 100.0% 41.4%
8e9gJ01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.82 69.0 4.87e-01 91.2% 76.6%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.81 66.0 5.23e-01 100.0% 44.7%
2qvaA02 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.80 60.0 6.18e-01 78.9% 94.3%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 68.0 6.10e-01 100.0% 68.8%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.79 58.0 4.18e-01 78.9% 78.5%
1cpyA02 1.10.287.410 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.78 59.0 5.56e-01 84.2% 68.1%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.77 63.0 6.07e-01 100.0% 78.5%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.77 69.0 5.77e-01 100.0% 60.4%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.76 62.0 4.93e-01 100.0% 44.8%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.76 62.0 5.14e-01 91.2% 61.8%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 63.0 5.91e-01 100.0% 74.6%
3rkoG00 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 63.0 5.21e-01 100.0% 53.0%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.75 61.0 4.79e-01 100.0% 43.0%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 65.0 4.73e-01 96.5% 74.0%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.74 64.0 4.53e-01 100.0% 32.0%
1p49A02 1.10.287.550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.73 62.0 6.17e-01 100.0% 91.5%
1m56C01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 58.0 5.47e-01 100.0% 72.5%
1luwA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.73 52.0 5.06e-01 77.2% 71.9%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.73 62.0 5.72e-01 100.0% 74.6%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.73 53.0 4.89e-01 82.5% 59.7%
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.72 55.0 5.12e-01 86.0% 64.5%
1rqgA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.72 60.0 4.48e-01 100.0% 36.4%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.71 62.0 4.15e-01 100.0% 25.2%
4u1cA01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.71 51.0 5.31e-01 78.9% 86.5%
2jvgA00 1.10.10.1270 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sbi, C3 binding domain IV 0.71 51.0 4.75e-01 78.9% 61.1%
2b7mA00 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.71 55.0 3.21e-01 98.2% 9.7%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 57.0 4.84e-01 100.0% 54.1%
1ucuA01 6.10.280.190 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 62.0 5.85e-01 100.0% 94.1%
6qs7C01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 60.0 4.55e-01 100.0% 40.2%
1kplA00 1.10.3080.10 Mainly Alpha › Orthogonal Bundle › Clc chloride channel › Clc chloride channel 0.70 58.0 3.43e-01 93.0% 13.5%
2kp8A00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.70 62.0 5.78e-01 100.0% 81.9%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 62.0 4.80e-01 100.0% 45.5%
1vmgA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.70 53.0 4.81e-01 86.0% 61.0%
3etuA01 1.10.287.3290 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 50.0 4.90e-01 78.9% 72.3%
3uo2B02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.70 54.0 4.89e-01 100.0% 60.7%
3nkzA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.69 54.0 4.65e-01 89.5% 56.7%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.69 56.0 4.37e-01 100.0% 40.8%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.69 54.0 5.55e-01 91.2% 100.0%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.69 51.0 4.52e-01 84.2% 97.8%
5b1aC01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 54.0 5.21e-01 100.0% 77.9%
1f7uA02 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.68 50.0 4.05e-01 84.2% 40.0%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.67 58.0 4.30e-01 100.0% 37.9%
3t9jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 60.0 4.44e-01 100.0% 79.2%
2wvxA04 1.20.1610.10 Mainly Alpha › Up-down Bundle › Glycosyl hydrolase family fold › alpha-1,2-mannosidases domains 0.67 57.0 4.12e-01 100.0% 38.2%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.67 56.0 4.49e-01 100.0% 90.3%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 55.0 4.23e-01 100.0% 78.1%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 51.0 4.57e-01 98.2% 60.0%
2jqtA00 1.20.1280.40 Mainly Alpha › Up-down Bundle › Monooxygenase › HHA 0.63 45.0 4.55e-01 87.7% 75.4%
4k08A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.63 55.0 4.13e-01 100.0% 79.2%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 52.0 4.99e-01 100.0% 100.0%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 51.0 4.76e-01 96.5% 82.2%
2ra1A02 1.20.58.780 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 41.0 4.00e-01 86.0% 64.7%
1dd3A01 1.20.5.710 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Single helix bin 0.52 36.0 3.64e-01 89.5% 78.9%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5001984 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.92 76.0 8.13e-01 98.2% 100.0%
4932480 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 83.0 5.41e-01 100.0% 25.9%
3973510 601.4.1.5 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › HBM 0.90 76.0 5.61e-01 100.0% 39.2%
5048408 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.89 76.0 7.72e-01 100.0% 94.5%
5044936 159.1.2.0 ↗ alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related 0.89 67.0 5.52e-01 78.9% 47.4%
1108845 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.89 71.0 7.67e-01 84.2% 100.0%
4994292 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.88 65.0 5.40e-01 77.2% 46.8%
4946791 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.88 74.0 6.74e-01 100.0% 69.3%
5006528 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.87 74.0 6.68e-01 100.0% 69.3%
3360875 7015.1.1.4 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › PLAC8 0.87 75.0 5.81e-01 100.0% 46.1%
3721382 192.29.1.175 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Pkr1 0.86 72.0 6.27e-01 100.0% 61.2%
3228061 1147.1.1.1 ↗ alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL 0.85 74.0 5.59e-01 100.0% 42.2%
3599042 109.1.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.85 67.0 4.37e-01 84.2% 21.8%
5047297 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.85 71.0 7.21e-01 100.0% 94.5%
3280288 5011.1.1.0 ↗ extended segments › Bacterial ba3 type cytochrome c oxidase subunit IIa › Bacterial ba3 type cytochrome c oxidase subunit IIa › Bacterial ba3 type cytochrome c oxidase subunit IIa 0.84 62.0 6.88e-01 78.9% 100.0%
5002089 2004.1.1.144 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2 0.83 73.0 4.44e-01 100.0% 16.8%
4018104 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 69.0 4.29e-01 100.0% 17.6%
4993195 632.6.1.15 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › PF26119 0.83 73.0 6.10e-01 96.5% 70.5%
3271624 2004.1.1.184 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.82 73.0 4.26e-01 100.0% 12.6%
3630657 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.81 69.0 5.87e-01 100.0% 58.9%
3486385 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.81 74.0 5.89e-01 100.0% 53.3%
4201121 192.7.1.0 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.81 74.0 7.30e-01 100.0% 93.3%
3655628 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.81 69.0 4.47e-01 100.0% 22.6%
3901696 192.8.1.240 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › HR1 0.81 71.0 6.03e-01 100.0% 62.4%
4784166 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.80 68.0 6.38e-01 100.0% 75.7%
5032963 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.80 70.0 4.90e-01 100.0% 33.1%
5069780 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.79 67.0 5.62e-01 100.0% 55.8%
3968647 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.79 70.0 6.74e-01 100.0% 86.2%
3672772 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.77 59.0 5.53e-01 82.5% 70.0%
3494796 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.77 65.0 4.13e-01 100.0% 19.6%
4628458 604.1.1.226 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF26877 0.76 62.0 5.35e-01 98.2% 58.8%
3503444 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.76 67.0 5.72e-01 100.0% 62.2%
4965923 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.75 62.0 4.36e-01 100.0% 28.6%
3612915 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.74 67.0 5.40e-01 100.0% 65.7%
4826575 150.1.1.5 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF305 0.73 66.0 6.31e-01 100.0% 93.8%
315449 192.8.1.2 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Hanta_nucleocap 0.73 64.0 5.84e-01 100.0% 73.7%
3878643 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 62.0 5.46e-01 96.5% 63.5%
3916403 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.73 62.0 5.46e-01 96.5% 63.5%
1203190 192.3.1.1 ↗ alpha bundles › Long alpha-hairpin › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Sod_Fe_N 0.73 62.0 5.20e-01 100.0% 57.0%
4955275 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.72 56.0 4.96e-01 100.0% 56.7%
4953503 2008.1.1.107 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD 0.71 63.0 4.27e-01 98.2% 51.0%
4798159 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 62.0 5.66e-01 100.0% 73.7%
4446039 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.60 46.0 4.45e-01 100.0% 74.3%
3596737 604.8.1.0 ↗ alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.54 41.0 3.34e-01 100.0% 40.0%