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YP_319879.1

Arc-Vir

NC_007409__YP_319879.1__ATV-gp48__00048

Identity

Accession:
NC_007409 ↗
Protein ID:
YP_319879.1 ↗
Kingdom:
archaea

Quality

84.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 329-421
PDB
Domain cluster: representative
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.87 49.0 5.62e-01 72.0% 74.6%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.83 72.0 5.67e-01 93.5% 89.1%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.79 65.0 5.53e-01 87.1% 86.9%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 52.0 4.92e-01 71.0% 57.9%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.78 54.0 5.57e-01 71.0% 95.4%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.77 68.0 5.31e-01 94.6% 87.2%
3vnxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.77 67.0 5.17e-01 93.5% 71.8%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 64.0 4.76e-01 93.5% 84.1%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 64.0 4.75e-01 93.5% 78.8%
4dylA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 67.0 4.94e-01 100.0% 79.6%
2ehwA00 6.10.140.1220 Special › Helix non-globular › Helix Hairpins › 0.74 54.0 4.98e-01 75.3% 84.3%
2hz8A00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.74 68.0 6.30e-01 100.0% 87.8%
3qhbA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.72 64.0 5.19e-01 100.0% 84.9%
3pt1A02 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.71 62.0 5.67e-01 94.6% 95.0%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.70 57.0 5.85e-01 94.6% 93.1%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.69 62.0 4.70e-01 100.0% 69.7%
1bhaA00 1.10.287.170 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 43.0 4.92e-01 71.0% 94.0%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.64 44.0 4.63e-01 72.0% 95.1%
1cm5A00 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.64 56.0 3.32e-01 100.0% 65.5%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.59 51.0 4.73e-01 94.6% 77.3%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.59 40.0 2.93e-01 73.1% 25.2%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.56 49.0 3.41e-01 100.0% 92.8%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3453285 3562.1.1.11 alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG 0.82 71.0 6.24e-01 93.5% 68.1%
3185197 192.5.1.17 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › DUF202 0.82 71.0 6.19e-01 92.5% 67.4%
3170797 605.4.1.4 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › DUF202 0.80 70.0 6.37e-01 93.5% 76.7%
3858356 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.79 54.0 4.62e-01 71.0% 94.5%
4018573 611.7.1.10 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Helo_like_N 0.78 68.0 5.05e-01 93.5% 60.0%
3441543 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.77 65.0 6.17e-01 91.4% 83.6%
3265161 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.74 51.0 5.19e-01 71.0% 76.7%
3817914 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.73 65.0 5.96e-01 100.0% 98.4%
3269731 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 51.0 4.81e-01 73.1% 65.2%
3579239 633.7.1.0 alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like 0.73 62.0 5.30e-01 95.7% 66.5%
3788505 3755.3.1.126 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PEX11 0.73 64.0 5.47e-01 94.6% 97.9%
4014677 3343.1.1.4 alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal, GCP_N_terminal, GCP5-Mod21_C 0.72 65.0 3.93e-01 100.0% 29.9%
3729395 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.72 60.0 5.45e-01 93.5% 67.7%
3469086 3755.4.1.17 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N 0.72 62.0 5.44e-01 95.7% 72.9%
3254077 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.71 62.0 5.20e-01 93.5% 63.9%
3693465 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.68 52.0 4.77e-01 80.6% 90.8%
3471617 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.67 59.0 5.25e-01 100.0% 74.8%
4026387 3403.1.1.6 alpha bundles › Pre-mRNA-splicing factor PRP9 › Pre-mRNA-splicing factor PRP9 › Pre-mRNA-splicing factor PRP9 › SF3a60_bindingd,SF3A3 0.63 58.0 3.94e-01 97.8% 41.7%
4963258 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.61 49.0 5.15e-01 93.5% 96.5%
D2 medium residues 14-113
PDB
Domain cluster: representative
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3i4gA00 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.81 73.0 4.53e-01 97.0% 95.5%
4nq0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.81 73.0 5.30e-01 97.0% 46.9%
3myvA01 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.77 68.0 5.11e-01 96.0% 92.4%
5tqbB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.77 63.0 4.34e-01 88.0% 33.1%
3kezA01 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.76 67.0 5.07e-01 97.0% 91.9%
3bqoA00 1.25.40.210 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain 0.75 68.0 5.36e-01 100.0% 58.9%
3snxA00 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.74 66.0 4.27e-01 99.0% 95.8%
3qkyA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.74 66.0 4.93e-01 100.0% 42.6%
4in3B00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.72 62.0 3.80e-01 94.0% 33.1%
4i9cA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.71 63.0 4.89e-01 98.0% 79.6%
4gyoA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.71 61.0 4.71e-01 94.0% 61.8%
2ijqA00 1.10.3450.10 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like 0.70 58.0 5.16e-01 91.0% 73.1%
1xnfA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.70 56.0 4.14e-01 87.0% 34.4%
3q15B00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 61.0 4.25e-01 98.0% 51.8%
2pziA04 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 57.0 4.74e-01 90.0% 59.9%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 47.0 4.43e-01 70.0% 89.3%
2katA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 60.0 5.73e-01 95.0% 82.6%
3qwwA03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 59.0 4.83e-01 98.0% 73.8%
2pqrA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 48.0 4.95e-01 80.0% 78.5%
2pftA00 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.67 60.0 3.82e-01 100.0% 34.7%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.66 46.0 4.47e-01 73.0% 72.3%
1elrA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 55.0 5.06e-01 91.0% 73.4%
7qihA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 53.0 5.31e-01 91.0% 87.1%
4gyoB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 56.0 5.04e-01 95.0% 100.0%
5ctrA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 55.0 3.95e-01 95.0% 49.2%
1s0pA01 1.25.40.330 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Adenylate cyclase-associated CAP, N-terminal domain 0.64 53.0 4.50e-01 92.0% 80.7%
2dbaA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 51.0 4.87e-01 92.0% 74.6%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 57.0 4.35e-01 97.0% 48.2%
4abnA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 55.0 4.02e-01 98.0% 50.9%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 54.0 4.49e-01 95.0% 93.1%
8fnyA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 54.0 4.28e-01 97.0% 72.3%
3vwaA03 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.62 54.0 3.87e-01 98.0% 48.3%
2ho1B00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 52.0 4.06e-01 95.0% 69.2%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.61 53.0 4.89e-01 97.0% 99.2%
4y6cA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 51.0 4.06e-01 94.0% 69.3%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 47.0 5.01e-01 85.0% 97.6%
3ay5A02 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.60 52.0 4.51e-01 99.0% 97.6%
3k9iA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 44.0 4.36e-01 81.0% 74.8%
3as5A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 51.0 4.23e-01 94.0% 65.7%
1ya0A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 51.0 4.13e-01 100.0% 47.6%
6tblB01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 46.0 4.49e-01 86.0% 89.2%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 52.0 4.00e-01 100.0% 88.2%
2m63A00 1.25.40.780 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.58 45.0 3.93e-01 85.0% 56.7%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.57 46.0 4.05e-01 89.0% 96.1%
2genA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 47.0 3.86e-01 91.0% 72.9%
3iq1B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 49.0 4.19e-01 97.0% 100.0%
7e4mA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.55 43.0 3.28e-01 87.0% 60.5%
2a0uB01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.54 46.0 3.97e-01 94.0% 72.5%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.54 41.0 3.92e-01 78.0% 71.7%
2d6yA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 45.0 3.74e-01 94.0% 69.4%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 48.0 4.86e-01 99.0% 100.0%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.53 43.0 4.25e-01 91.0% 99.1%
3juiA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 43.0 3.66e-01 90.0% 60.3%
1ldjA04 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.53 44.0 4.25e-01 92.0% 91.3%
2pz9A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 43.0 3.55e-01 92.0% 68.2%
ECOD (82)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3168521 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.81 74.0 5.33e-01 98.0% 45.7%
3681643 109.4.1.146 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cohesin_load 0.80 71.0 4.63e-01 93.0% 74.9%
3550455 109.4.1.508 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › KBP_C 0.79 72.0 4.87e-01 100.0% 54.9%
3927844 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.78 68.0 5.05e-01 95.0% 53.5%
3797852 109.4.1.386 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Rapsyn_N 0.77 70.0 4.42e-01 97.0% 30.9%
3509325 109.4.1.235 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 0.75 68.0 4.53e-01 100.0% 46.7%
3387127 109.4.1.206 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › YfiO 0.75 67.0 5.45e-01 99.0% 58.4%
3688535 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.75 62.0 4.12e-01 90.0% 26.8%
3740160 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 64.0 4.88e-01 96.0% 48.9%
3596951 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 64.0 4.22e-01 95.0% 88.0%
5069798 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 64.0 4.33e-01 96.0% 78.1%
3754579 109.4.1.508 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › KBP_C 0.72 63.0 5.27e-01 97.0% 85.1%
1674770 109.4.1.146 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cohesin_load 0.72 57.0 3.45e-01 83.0% 15.2%
3258479 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 62.0 5.31e-01 92.0% 66.5%
4517214 109.4.1.253 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RapH_N 0.72 62.0 5.57e-01 95.0% 82.1%
4022062 109.4.1.1320 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_10, TPR_12 0.72 63.0 4.74e-01 97.0% 61.3%
3715367 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 63.0 4.26e-01 97.0% 41.9%
2140427 109.4.1.206 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › YfiO 0.71 64.0 5.00e-01 100.0% 48.6%
3551590 109.4.1.1647 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28330 0.71 58.0 4.68e-01 89.0% 73.8%
3506555 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 58.0 5.69e-01 90.0% 85.5%
3597190 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 60.0 3.96e-01 93.0% 42.0%
3630542 109.4.1.264 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RMD1-3 0.70 57.0 5.57e-01 88.0% 100.0%
3412260 109.4.1.1581 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29127 0.70 62.0 4.27e-01 100.0% 78.6%
3764056 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 60.0 4.87e-01 95.0% 60.0%
4997238 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.70 60.0 4.88e-01 96.0% 53.3%
3603138 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 61.0 5.60e-01 97.0% 84.6%
3279540 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 58.0 4.79e-01 92.0% 60.5%
3821368 109.4.1.1286 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 0.70 58.0 5.42e-01 91.0% 80.8%
4611956 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 62.0 4.08e-01 98.0% 71.8%
3712280 109.4.1.1774 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_CFAP46_N 0.70 59.0 4.63e-01 94.0% 54.4%
4050251 109.4.1.1627 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12, RapH_N 0.69 61.0 4.15e-01 97.0% 61.6%
3645154 109.4.1.1315 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_8, TPR_10, TPR_12 0.69 61.0 3.99e-01 97.0% 34.0%
3688003 109.4.1.191 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7 0.69 60.0 3.93e-01 95.0% 26.2%
3601742 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 60.0 4.24e-01 97.0% 48.1%
3698487 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 60.0 4.07e-01 97.0% 75.7%
3600392 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 60.0 4.45e-01 97.0% 59.6%
4496821 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 62.0 4.19e-01 97.0% 47.9%
3520433 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 58.0 4.56e-01 93.0% 46.2%
3707418 109.4.1.285 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PSMD12-CSN4_N 0.68 60.0 4.11e-01 97.0% 42.5%
4022159 109.4.1.146 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cohesin_load 0.68 58.0 4.26e-01 95.0% 38.2%
3898993 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 57.0 4.14e-01 92.0% 34.9%
3257076 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 54.0 4.83e-01 88.0% 70.3%
3232478 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 59.0 4.67e-01 98.0% 69.8%
5022183 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.67 57.0 4.75e-01 94.0% 89.7%
3511390 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 56.0 4.63e-01 93.0% 60.6%
3196444 109.4.1.1290 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_19 0.66 58.0 4.76e-01 98.0% 96.8%
3744745 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 55.0 3.91e-01 91.0% 64.7%
3882100 109.4.1.371 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RTP1_C1 0.66 57.0 4.22e-01 96.0% 58.8%
1406322 109.4.1.2096 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6, TPR_19, PF30363, PF30475 0.65 55.0 3.39e-01 93.0% 17.3%
3618284 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 56.0 3.99e-01 97.0% 32.2%
3388439 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.65 60.0 4.38e-01 100.0% 94.6%
3258721 109.4.1.218 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP 0.65 57.0 4.11e-01 96.0% 71.8%
4061592 109.4.1.218 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP 0.65 57.0 4.16e-01 100.0% 71.5%
3625558 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.65 52.0 4.73e-01 86.0% 83.7%
3505926 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 56.0 4.09e-01 98.0% 76.3%
3284763 109.4.1.1418 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_12 0.65 54.0 4.69e-01 91.0% 67.7%
3622849 109.4.1.218 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP 0.64 56.0 4.08e-01 99.0% 49.8%
3997498 109.4.1.146 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cohesin_load 0.64 56.0 4.68e-01 99.0% 81.7%
3372104 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 54.0 4.93e-01 94.0% 71.1%
3999694 109.26.1.12 alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › TPR_Nup160_C, TPR_NUP160_120_M 0.64 52.0 3.78e-01 93.0% 39.7%
4535883 109.4.1.317 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med5 0.64 52.0 4.06e-01 89.0% 71.6%
3490147 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 55.0 4.30e-01 97.0% 45.0%
4527327 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 55.0 4.68e-01 100.0% 90.9%
3369159 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 55.0 3.73e-01 98.0% 49.2%
3461922 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.62 55.0 4.20e-01 98.0% 66.0%
3787724 109.4.1.171 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › U3snoRNP10 0.62 54.0 3.61e-01 98.0% 62.1%
3726855 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.62 54.0 4.79e-01 96.0% 76.2%
3272245 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.62 56.0 4.06e-01 99.0% 93.3%
5016952 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 54.0 3.74e-01 99.0% 68.6%
4336397 109.4.1.15 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VHS 0.61 51.0 4.34e-01 94.0% 61.7%
3217535 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 51.0 4.19e-01 91.0% 97.3%
3657968 109.4.1.1258 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2 0.61 52.0 3.68e-01 94.0% 43.5%
4945270 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 50.0 4.54e-01 91.0% 79.3%
3510805 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 49.0 4.36e-01 89.0% 66.2%
3739261 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 52.0 3.81e-01 98.0% 79.3%
3804928 109.59.1.18 alpha superhelices › Repetitive alpha hairpins › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Intraflagellar transport protein 80 (IFT80) C-terminal domain › RIC1 0.59 51.0 3.60e-01 100.0% 29.4%
3364365 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.58 51.0 3.79e-01 97.0% 61.2%
3527434 6006.1.1.6 extended segments › Voltage gated calcium channel IQ domain › Voltage gated calcium channel IQ domain › Voltage gated calcium channel IQ domain › PF27661 0.57 39.0 3.37e-01 78.0% 45.8%
3534896 109.4.1.371 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RTP1_C1 0.56 48.0 3.09e-01 98.0% 33.4%
3605533 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 46.0 3.51e-01 98.0% 46.9%
3606791 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 45.0 3.29e-01 94.0% 40.0%
3883670 604.1.1.7 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 0.54 47.0 4.44e-01 96.0% 92.5%
D3 medium residues 114-163
PDB
Domain cluster: representative
CATH (54)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.89 67.0 4.67e-01 80.0% 32.2%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.87 64.0 4.29e-01 78.0% 25.7%
8g0lB01 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.86 76.0 4.44e-01 98.0% 13.2%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.86 64.0 5.60e-01 78.0% 63.4%
4i17A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.86 70.0 4.49e-01 90.0% 21.0%
1elrA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.84 71.0 5.22e-01 94.0% 36.7%
1hr5A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.84 63.0 6.41e-01 80.0% 91.7%
7yb9A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.83 72.0 4.68e-01 98.0% 26.1%
2pl2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.83 65.0 4.28e-01 86.0% 22.7%
1o9gA02 1.10.287.540 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.82 58.0 6.18e-01 76.0% 93.0%
3vtxB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.82 67.0 4.54e-01 92.0% 25.7%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.81 60.0 5.36e-01 80.0% 64.8%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.81 60.0 5.53e-01 80.0% 82.8%
2pziB03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.81 66.0 4.68e-01 92.0% 32.0%
2xpiD00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.80 66.0 3.76e-01 92.0% 8.9%
1elwA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.80 65.0 4.99e-01 92.0% 40.2%
4rg9B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.80 67.0 4.58e-01 92.0% 28.1%
5nnpE01 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.79 69.0 3.94e-01 98.0% 18.5%
2kc7A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.79 65.0 5.27e-01 94.0% 48.5%
2nr4A02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.79 56.0 5.36e-01 76.0% 69.0%
2wj9B00 3.30.70.3580 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Antirestriction protein 0.78 69.0 4.89e-01 98.0% 66.2%
6fdpA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.78 63.0 4.83e-01 92.0% 39.2%
4gywA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.78 64.0 4.98e-01 92.0% 42.3%
5djsA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.78 65.0 4.65e-01 92.0% 32.9%
7qihA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.78 64.0 5.11e-01 92.0% 52.5%
4u04B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.78 65.0 5.48e-01 96.0% 55.7%
8h1kA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.78 71.0 4.09e-01 100.0% 34.1%
2lseA00 1.20.120.1360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.78 67.0 5.35e-01 98.0% 57.4%
4gywA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.78 63.0 5.00e-01 92.0% 44.8%
3fflA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.77 62.0 4.69e-01 92.0% 41.3%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.76 63.0 4.48e-01 92.0% 30.7%
1cpyA02 1.10.287.410 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 54.0 4.83e-01 76.0% 55.6%
4lctB00 1.25.40.570 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.76 62.0 3.70e-01 92.0% 14.4%
1ks8A00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.75 64.0 3.71e-01 96.0% 21.2%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.75 68.0 5.61e-01 100.0% 86.0%
4cj0A02 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.75 64.0 3.69e-01 94.0% 20.5%
1dq3A02 3.30.160.90 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.75 57.0 4.92e-01 82.0% 84.2%
4ui9Y03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.74 61.0 5.25e-01 92.0% 63.7%
2afaA00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.74 64.0 3.75e-01 100.0% 23.0%
8carA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.73 66.0 3.88e-01 100.0% 26.7%
5gxxA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.72 61.0 3.58e-01 98.0% 27.1%
6ljaA01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.72 63.0 3.74e-01 100.0% 23.9%
4wu0A00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.68 57.0 3.46e-01 98.0% 23.9%
6z0fA02 1.25.40.680 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain 0.68 56.0 4.01e-01 100.0% 35.5%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.67 55.0 4.53e-01 98.0% 85.3%
4fnvA01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.67 55.0 3.35e-01 98.0% 27.1%
3u4qA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 54.0 3.44e-01 94.0% 40.8%
4k08A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.56 39.0 2.95e-01 78.0% 89.6%
1uouA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.56 43.0 4.03e-01 92.0% 73.5%
3rbtA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 42.0 3.43e-01 96.0% 59.0%
4gtnA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.54 42.0 3.84e-01 92.0% 66.2%
1vquA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.52 41.0 3.83e-01 94.0% 73.1%
4muoA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.52 40.0 3.68e-01 92.0% 73.6%
2elcA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.50 37.0 3.55e-01 90.0% 70.1%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3904046 109.4.1.174 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPPII_C 0.95 83.0 5.12e-01 92.0% 19.7%
4969419 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.94 82.0 4.99e-01 92.0% 17.7%
3479741 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.90 83.0 6.04e-01 100.0% 42.4%
3215082 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.90 67.0 4.72e-01 78.0% 33.3%
3166807 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.89 75.0 4.97e-01 92.0% 24.9%
3488973 109.4.1.2241 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_2, TPR_8, TPR_19 0.89 73.0 4.99e-01 90.0% 27.3%
3525931 109.4.1.1421 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_19 0.89 73.0 4.97e-01 90.0% 27.3%
3175619 109.4.1.161 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › mTOR_dom 0.89 75.0 3.92e-01 92.0% 3.4%
3863036 109.4.1.362 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_8 0.88 73.0 4.89e-01 90.0% 25.7%
3922067 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.88 74.0 4.51e-01 92.0% 16.1%
4201121 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.88 67.0 6.23e-01 80.0% 76.7%
3323491 109.4.1.1979 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP72, SRP_TPR_like 0.88 75.0 4.16e-01 92.0% 8.1%
315449 192.8.1.2 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Hanta_nucleocap 0.88 67.0 5.68e-01 80.0% 78.9%
3341289 109.4.1.2315 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP72, TPR_6, SRP_TPR_like 0.87 73.0 4.09e-01 92.0% 8.2%
3257393 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.87 77.0 5.09e-01 100.0% 28.4%
3387291 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.86 73.0 5.80e-01 92.0% 48.4%
3590183 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.86 72.0 5.36e-01 92.0% 38.3%
3697044 109.4.1.186 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANAPC3 0.86 72.0 4.47e-01 92.0% 17.7%
3691909 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.86 71.0 5.07e-01 90.0% 33.3%
3400811 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.86 74.0 5.76e-01 96.0% 46.7%
3574716 109.4.1.1312 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30475 0.85 73.0 5.89e-01 96.0% 51.6%
3932343 109.4.1.2532 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_6, TPR_8, TPR_16, TPR_19 0.85 76.0 4.47e-01 100.0% 14.9%
3785633 109.4.1.1999 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12, TPR_16 0.85 73.0 4.93e-01 96.0% 27.2%
5002089 2004.1.1.144 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2 0.85 64.0 3.81e-01 80.0% 14.6%
3901696 192.8.1.240 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › HR1 0.85 63.0 5.24e-01 80.0% 54.1%
3271624 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.84 63.0 3.62e-01 80.0% 10.6%
4019794 109.4.1.140 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NatB_MDM20 0.84 70.0 4.22e-01 94.0% 15.1%
3318779 109.4.1.362 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_8 0.84 72.0 5.09e-01 94.0% 33.1%
3680698 109.4.1.1300 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_16, TPR_19 0.84 75.0 4.59e-01 100.0% 16.9%
3411530 109.4.1.2031 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, ANAPC3, TPR_8 0.84 69.0 3.87e-01 92.0% 8.0%
3169810 109.4.1.3091 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_2, ANAPC3, TPR_8, TPR_12 0.84 70.0 3.81e-01 92.0% 6.3%
3368647 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.83 75.0 4.83e-01 100.0% 25.6%
3654538 109.4.1.631 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP72 0.83 69.0 4.19e-01 92.0% 15.1%
3483518 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.83 70.0 5.19e-01 94.0% 37.6%
3739941 109.4.1.8 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_12 0.83 71.0 4.87e-01 96.0% 28.8%
3249202 101.3.1.0 alpha arrays › HTH › XPC-binding domain › XPC-binding domain 0.83 74.0 4.43e-01 100.0% 15.8%
5040468 109.4.1.210 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 0.83 69.0 4.78e-01 92.0% 29.1%
3754465 109.4.1.1286 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 0.82 74.0 4.31e-01 100.0% 15.7%
4901746 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.82 62.0 4.50e-01 80.0% 35.4%
3829881 109.4.1.186 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANAPC3 0.82 69.0 4.54e-01 92.0% 24.1%
3188106 109.4.1.3556 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANAPC3, TPR_8, TPR_10, TPR_16 0.82 68.0 3.74e-01 92.0% 6.9%
3502787 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.81 68.0 5.04e-01 92.0% 36.8%
2875706 109.4.1.1613 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, ANAPC3, TPR_8 0.81 67.0 5.33e-01 92.0% 46.5%
3605707 109.4.1.1264 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_16 0.81 66.0 3.97e-01 92.0% 13.6%
3610731 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.81 67.0 5.08e-01 92.0% 40.0%
3548425 109.4.1.186 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANAPC3 0.80 68.0 4.52e-01 92.0% 25.4%
2814209 109.4.1.1294 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, ANAPC3, TPR_8, TPR_12, TPR_16 0.80 67.0 4.56e-01 92.0% 26.9%
3594073 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.80 69.0 4.11e-01 96.0% 13.3%
3276093 109.4.1.3283 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, ANAPC8, ANAPC3, TPR_8, RMD1-3 0.79 72.0 3.99e-01 100.0% 61.5%
4981019 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.79 64.0 4.55e-01 92.0% 29.7%
3738314 109.4.1.3094 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, ANAPC3, TPR_8, TPR_19 0.78 68.0 3.77e-01 98.0% 62.7%
3652175 109.4.1.2678 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, ANAPC3, TPR_8, TPR_12, TPR_19 0.77 68.0 3.81e-01 98.0% 60.9%
5032313 101.1.2.150 alpha arrays › HTH › HTH › winged helix domain › HTH_45 0.77 63.0 4.95e-01 94.0% 85.5%
3310047 109.4.1.1822 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, ANAPC3, TPR_8, TPR_16, TPR_19 0.77 69.0 3.89e-01 100.0% 58.5%
3585244 109.4.1.2012 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANAPC3, TPR_8, TPR_16 0.76 69.0 3.99e-01 100.0% 80.0%
3875598 109.4.1.1877 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, ANAPC3, TPR_8, TPR_16 0.76 68.0 3.81e-01 100.0% 56.1%
3271432 109.4.1.1933 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_14, TPR_19, HAT_PRP39_N 0.76 61.0 4.41e-01 92.0% 32.0%
3995841 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.75 61.0 3.96e-01 94.0% 20.0%
3220020 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 61.0 3.73e-01 92.0% 20.3%
3876892 375.2.1.0 few secondary structure elements › Rubredoxin-like › YfgJ-like › YfgJ-like 0.73 61.0 5.41e-01 100.0% 62.5%
3577239 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.70 64.0 4.02e-01 100.0% 69.2%
5044963 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 58.0 4.19e-01 92.0% 46.4%
D4 medium residues 164-239
PDB
Domain cluster: representative
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.89 69.0 6.74e-01 80.3% 77.8%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.89 81.0 5.84e-01 96.1% 78.7%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.89 65.0 5.68e-01 76.3% 55.0%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.88 67.0 4.67e-01 78.9% 73.7%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.88 65.0 5.64e-01 77.6% 59.8%
4abxA02 6.10.140.1090 Special › Helix non-globular › Helix Hairpins › 0.88 65.0 6.22e-01 77.6% 72.4%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.87 64.0 5.68e-01 77.6% 59.4%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.86 65.0 4.51e-01 78.9% 29.1%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.84 63.0 4.09e-01 78.9% 55.3%
1aluA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.81 57.0 4.45e-01 73.7% 42.7%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.81 65.0 6.40e-01 85.5% 92.6%
2cazD00 6.10.140.820 Special › Helix non-globular › Helix Hairpins › 0.80 58.0 6.48e-01 76.3% 100.0%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.80 52.0 5.41e-01 72.4% 71.8%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 57.0 6.24e-01 75.0% 95.0%
2incB00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.79 60.0 3.91e-01 81.6% 45.0%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.78 64.0 5.61e-01 88.2% 70.0%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.77 57.0 5.03e-01 77.6% 54.6%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 60.0 5.22e-01 82.9% 70.8%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 52.0 5.78e-01 73.7% 93.2%
3o7pA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.75 60.0 4.27e-01 85.5% 31.7%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.75 67.0 5.50e-01 98.7% 96.3%
5lbmA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.75 60.0 5.89e-01 86.8% 92.8%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 52.0 5.79e-01 75.0% 96.6%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.73 54.0 4.47e-01 78.9% 44.4%
4cmyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.73 59.0 4.65e-01 89.5% 84.7%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.73 67.0 5.33e-01 100.0% 83.4%
3sfvB02 6.10.140.2010 Special › Helix non-globular › Helix Hairpins › 0.72 61.0 4.56e-01 96.1% 94.0%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 55.0 5.09e-01 82.9% 71.1%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 49.0 5.05e-01 71.1% 83.6%
1bhaA00 1.10.287.170 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 55.0 5.89e-01 96.1% 92.5%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.72 53.0 5.45e-01 82.9% 84.5%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 54.0 4.22e-01 81.6% 44.4%
4adzA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.70 57.0 5.40e-01 88.2% 88.9%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.70 53.0 5.05e-01 94.7% 70.1%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.70 48.0 4.03e-01 71.1% 81.4%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 51.0 5.17e-01 77.6% 85.1%
4fb2A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.69 44.0 2.75e-01 90.8% 12.5%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.69 51.0 4.44e-01 78.9% 54.7%
3qf7A02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 52.0 5.61e-01 92.1% 96.8%
2d9dA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.68 48.0 4.57e-01 78.9% 62.9%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.68 50.0 5.06e-01 77.6% 81.1%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 55.0 4.65e-01 92.1% 63.2%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.67 53.0 5.21e-01 88.2% 90.6%
1rqgA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.67 47.0 3.79e-01 73.7% 38.4%
2z1qB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 56.0 4.69e-01 94.7% 55.1%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 56.0 4.57e-01 94.7% 51.4%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.64 50.0 4.80e-01 96.1% 73.6%
5fmnA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.64 54.0 5.23e-01 96.1% 98.8%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 56.0 4.16e-01 98.7% 66.7%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.63 54.0 4.29e-01 96.1% 75.5%
3gs3A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.59 43.0 3.09e-01 78.9% 35.7%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.54 40.0 3.97e-01 80.3% 97.6%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3626316 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.92 72.0 5.84e-01 96.1% 47.7%
3586089 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.90 70.0 5.21e-01 96.1% 36.5%
5007124 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.89 67.0 4.36e-01 78.9% 54.1%
3698336 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.88 63.0 6.09e-01 78.9% 67.1%
3386594 3291.1.1.197 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › MCPsignal 0.87 67.0 5.89e-01 80.3% 63.8%
4171766 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.87 63.0 5.96e-01 76.3% 64.4%
3574626 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.86 65.0 5.23e-01 80.3% 47.1%
4997871 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.85 66.0 5.73e-01 96.1% 56.4%
3788539 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.85 64.0 3.92e-01 78.9% 16.5%
3996346 601.1.1.3 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PDC10_C 0.85 60.0 4.71e-01 75.0% 37.3%
3407613 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.84 71.0 5.74e-01 94.7% 50.0%
3731299 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.83 66.0 4.64e-01 82.9% 65.2%
3694833 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 62.0 5.13e-01 78.9% 87.7%
3258825 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.82 62.0 3.82e-01 78.9% 16.7%
3911582 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.81 69.0 5.48e-01 96.1% 46.7%
4964379 5039.1.1.1 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 0.81 61.0 4.17e-01 80.3% 24.7%
3788505 3755.3.1.126 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PEX11 0.81 74.0 5.89e-01 100.0% 93.1%
3212065 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.80 65.0 5.33e-01 96.1% 48.9%
4954895 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.80 48.0 4.55e-01 75.0% 51.1%
3664049 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.78 54.0 4.24e-01 72.4% 83.9%
4438700 622.1.1.0 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.78 57.0 5.51e-01 77.6% 78.8%
4930182 2498.1.1.10 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.78 65.0 4.72e-01 89.5% 64.6%
3195189 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.77 59.0 4.23e-01 84.2% 62.2%
3574954 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.76 68.0 4.97e-01 100.0% 78.5%
3441543 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.76 66.0 5.78e-01 94.7% 70.0%
3722652 109.46.1.1 alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH 0.75 58.0 4.52e-01 80.3% 48.0%
3758339 5086.1.1.65 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › USHBP1_PDZ-bd 0.75 50.0 4.75e-01 73.7% 57.8%
3650825 3718.1.1.20 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › DUF6490 0.74 61.0 5.18e-01 90.8% 56.8%
227631 3282.1.1.1 a+b complex topology › LidA › LidA › LidA › LidA_Long_CC 0.74 65.0 4.24e-01 98.7% 85.4%
3795144 3615.1.1.9 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › TMEM72 0.74 63.0 5.20e-01 94.7% 53.8%
3518039 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.73 52.0 4.64e-01 77.6% 54.3%
3586382 601.1.2.4 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.72 63.0 5.76e-01 96.1% 77.0%
3631853 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.72 59.0 4.57e-01 90.8% 42.0%
3838968 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.71 51.0 4.22e-01 77.6% 42.2%
3931307 601.1.2.4 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.71 60.0 4.90e-01 94.7% 51.0%
3654589 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.71 61.0 5.76e-01 92.1% 80.0%
5063047 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.71 51.0 4.73e-01 77.6% 65.0%
3949864 632.1.1.37 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › DUF6474 0.70 53.0 5.06e-01 88.2% 68.9%
3593068 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 53.0 3.89e-01 89.5% 31.0%
4998576 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.69 52.0 5.27e-01 86.8% 80.0%
3698361 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.69 58.0 5.43e-01 94.7% 82.1%
5007621 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.67 51.0 4.81e-01 96.1% 66.3%
3276690 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.66 57.0 4.73e-01 96.1% 83.7%
3918068 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.66 50.0 4.39e-01 82.9% 79.1%
3739028 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 49.0 3.17e-01 81.6% 25.3%
2859434 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.64 54.0 3.99e-01 96.1% 45.5%
3884035 611.2.1.0 alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) 0.63 51.0 4.34e-01 88.2% 93.6%
4963832 5069.1.1.107 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Exosortase_EpsH 0.59 52.0 3.57e-01 100.0% 93.0%
D5 medium residues 240-328
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.82 59.0 6.38e-01 74.2% 100.0%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.81 60.0 5.91e-01 76.4% 98.9%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.81 58.0 5.61e-01 74.2% 87.6%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.80 55.0 5.88e-01 70.8% 100.0%
3rauA00 1.25.40.280 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains 0.80 73.0 4.72e-01 97.8% 86.3%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.79 54.0 4.75e-01 70.8% 68.3%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.79 55.0 4.92e-01 71.9% 68.9%
2vkjA00 1.20.58.2030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 53.0 5.01e-01 70.8% 59.4%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.77 56.0 5.44e-01 76.4% 69.0%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.77 59.0 5.67e-01 80.9% 100.0%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.76 55.0 4.92e-01 74.2% 74.6%
4wnfA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.76 53.0 3.79e-01 73.0% 26.3%
6wb9201 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.75 52.0 3.52e-01 70.8% 32.5%
1ya0A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.74 55.0 4.19e-01 78.7% 35.4%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.74 57.0 5.44e-01 80.9% 100.0%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 57.0 5.46e-01 82.0% 99.0%
1hz4A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.73 51.0 3.37e-01 73.0% 67.8%
2vgxB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.73 51.0 4.27e-01 76.4% 44.1%
2a0bA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.71 51.0 4.65e-01 75.3% 59.3%
4lctB00 1.25.40.570 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.70 54.0 3.60e-01 83.1% 21.0%
2wwxB00 1.20.1260.70 Mainly Alpha › Up-down Bundle › Ferritin › 0.69 54.0 4.08e-01 82.0% 86.5%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 60.0 4.23e-01 93.3% 74.9%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 49.0 4.27e-01 74.2% 80.2%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.57 40.0 4.05e-01 71.9% 82.6%
ECOD (51)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3691909 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.90 61.0 5.19e-01 73.0% 45.9%
5057380 109.7.1.0 alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E 0.90 73.0 6.42e-01 85.4% 64.0%
3648386 109.4.1.5 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.89 67.0 5.23e-01 77.5% 44.7%
3616725 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.89 60.0 5.14e-01 71.9% 46.9%
3603137 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.89 66.0 5.19e-01 76.4% 43.6%
3901767 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.89 60.0 4.48e-01 71.9% 31.0%
4524449 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.89 64.0 4.87e-01 94.4% 35.3%
3834437 109.4.1.5 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.88 71.0 4.74e-01 84.3% 26.9%
5062478 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.88 68.0 6.86e-01 80.9% 100.0%
3356163 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.87 71.0 5.10e-01 85.4% 53.9%
3890931 109.4.1.2123 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_17 0.87 67.0 4.89e-01 87.6% 32.7%
3377566 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.86 71.0 4.55e-01 86.5% 23.6%
3569969 109.4.1.202 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 0.85 60.0 4.12e-01 75.3% 24.2%
5022166 109.4.1.922 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_9 0.85 61.0 4.20e-01 74.2% 30.5%
3665244 109.7.1.0 alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E 0.85 61.0 4.96e-01 78.7% 42.6%
5049135 109.7.1.0 alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E 0.84 62.0 7.01e-01 91.0% 97.1%
5055698 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.84 77.0 5.08e-01 100.0% 40.6%
4980458 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.84 62.0 4.39e-01 78.7% 28.3%
3448598 3932.1.1.0 alpha bundles › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain 0.83 55.0 6.67e-01 71.9% 100.0%
3606341 109.4.1.1433 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_8, TPR_12 0.83 57.0 4.46e-01 70.8% 39.4%
3376249 109.4.1.1666 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_10 0.83 64.0 3.89e-01 80.9% 15.4%
5050536 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.82 61.0 6.81e-01 77.5% 100.0%
3621994 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.82 63.0 5.35e-01 79.8% 60.0%
3372240 650.1.1.0 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain 0.82 65.0 3.86e-01 84.3% 13.0%
3870335 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.82 59.0 4.17e-01 75.3% 29.0%
3498003 109.4.1.626 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TRAPPC9-Trs120 0.82 63.0 4.70e-01 80.9% 39.5%
3262215 109.4.1.2075 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_2, TPR_19 0.82 63.0 4.65e-01 94.4% 33.8%
5057382 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.82 76.0 5.60e-01 100.0% 44.7%
5051079 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.81 60.0 4.75e-01 77.5% 41.2%
3504180 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.80 56.0 4.43e-01 71.9% 39.4%
3819648 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.80 57.0 4.06e-01 73.0% 27.7%
3657665 101.3.1.0 alpha arrays › HTH › XPC-binding domain › XPC-binding domain 0.80 63.0 4.47e-01 84.3% 63.9%
5056292 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.80 72.0 6.39e-01 97.8% 93.6%
5033222 375.1.1.26 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 0.79 61.0 5.71e-01 79.8% 89.5%
3975400 109.4.1.1555 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_19 0.79 65.0 4.28e-01 89.9% 22.6%
3940186 226.1.1.0 a+b two layers › POZ domain › POZ domain › POZ domain 0.79 57.0 6.02e-01 75.3% 91.3%
5055770 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 72.0 6.44e-01 97.8% 75.8%
3990218 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.79 60.0 3.72e-01 79.8% 16.3%
3388400 109.4.1.1264 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_16 0.79 61.0 3.55e-01 95.5% 9.9%
5055533 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.78 72.0 6.09e-01 98.9% 84.3%
3255977 109.4.1.1134 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_INTS8_3 0.78 56.0 3.91e-01 75.3% 35.9%
4932747 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.77 55.0 5.26e-01 73.0% 71.0%
3456188 109.7.1.10 alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E › WAV3_C 0.77 56.0 6.03e-01 76.4% 100.0%
3472152 109.4.1.626 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TRAPPC9-Trs120 0.77 64.0 4.35e-01 89.9% 26.6%
5071225 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.77 54.0 4.93e-01 73.0% 60.0%
4998508 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.76 56.0 4.27e-01 76.4% 35.8%
5051493 109.3.1.473 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › TPR_8 0.75 68.0 4.62e-01 95.5% 42.5%
3424395 109.4.1.95 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2 0.74 55.0 5.13e-01 86.5% 62.7%
3758614 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 64.0 3.60e-01 97.8% 60.4%
5050100 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.71 48.0 4.18e-01 70.8% 45.9%
3372695 109.4.1.3015 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_7, TPR_8, TPR_12, TPR_19 0.63 53.0 3.30e-01 95.5% 57.9%
D6 medium residues 442-521
PDB
Domain cluster: representative
CATH (73)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4gzrB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.83 64.0 6.52e-01 88.7% 84.4%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.82 75.0 6.27e-01 100.0% 66.2%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.82 69.0 4.85e-01 91.3% 30.9%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.80 67.0 5.07e-01 91.3% 92.9%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.80 67.0 6.33e-01 91.3% 85.1%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.80 66.0 6.48e-01 88.7% 91.8%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.79 64.0 5.93e-01 91.3% 68.6%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.79 62.0 6.69e-01 86.3% 100.0%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.78 66.0 5.52e-01 91.3% 57.9%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.78 64.0 6.30e-01 91.3% 82.8%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.77 65.0 5.78e-01 91.3% 67.0%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.77 64.0 4.39e-01 91.3% 28.0%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 61.0 6.43e-01 91.3% 97.2%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 57.0 6.21e-01 86.3% 100.0%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 63.0 4.85e-01 91.3% 41.4%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.76 62.0 5.92e-01 100.0% 75.8%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.76 63.0 5.00e-01 91.3% 49.1%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.76 52.0 5.51e-01 88.7% 80.3%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 68.0 5.14e-01 100.0% 94.2%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.75 67.0 5.85e-01 98.8% 76.5%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 61.0 4.49e-01 90.0% 33.6%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.75 63.0 5.95e-01 92.5% 95.8%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.74 46.0 5.45e-01 91.3% 98.0%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.74 63.0 6.29e-01 91.3% 97.6%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 54.0 5.54e-01 82.5% 80.5%
3m9vA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.73 66.0 5.26e-01 100.0% 55.4%
1vx7301 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 50.0 5.24e-01 71.2% 87.8%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.73 61.0 5.14e-01 98.8% 54.9%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.73 57.0 6.10e-01 87.5% 100.0%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.73 67.0 5.59e-01 100.0% 89.4%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.73 57.0 6.06e-01 85.0% 100.0%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.73 46.0 3.96e-01 77.5% 41.1%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.73 58.0 6.09e-01 90.0% 98.6%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.73 59.0 5.95e-01 88.7% 92.5%
3rx6A00 1.20.58.1090 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer 0.72 64.0 4.92e-01 100.0% 82.9%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.72 59.0 5.96e-01 90.0% 100.0%
8cdaB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.72 64.0 5.13e-01 100.0% 56.0%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.72 60.0 6.01e-01 90.0% 92.6%
4q20A01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.72 54.0 5.44e-01 90.0% 79.3%
3b2eF00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.71 52.0 5.66e-01 83.7% 100.0%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 60.0 5.15e-01 93.8% 71.9%
3vbbE01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.71 59.0 5.16e-01 91.3% 70.6%
3tu3B03 1.20.1050.100 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.69 49.0 3.83e-01 100.0% 34.7%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.69 47.0 5.15e-01 72.5% 90.3%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.69 58.0 5.67e-01 93.8% 96.7%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.69 55.0 5.65e-01 91.3% 93.5%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.69 61.0 5.12e-01 100.0% 63.8%
2oauA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 51.0 4.70e-01 78.8% 61.8%
2nr4A02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.68 44.0 5.08e-01 100.0% 91.4%
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.68 51.0 5.50e-01 85.0% 100.0%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.68 57.0 5.14e-01 92.5% 74.3%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 55.0 5.62e-01 88.7% 98.7%
1j30A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 58.0 4.89e-01 97.5% 60.3%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 60.0 5.49e-01 97.5% 89.3%
4rm7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 52.0 4.45e-01 88.7% 49.6%
4l6rA02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.66 56.0 3.88e-01 96.2% 58.6%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 57.0 5.32e-01 100.0% 83.7%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 54.0 5.36e-01 91.3% 88.0%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.65 59.0 5.00e-01 100.0% 61.2%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.64 40.0 4.18e-01 71.2% 67.6%
1luwA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.64 47.0 5.09e-01 86.3% 100.0%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.64 54.0 4.93e-01 96.2% 75.2%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 53.0 5.04e-01 93.8% 82.5%
3au3A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.62 55.0 3.74e-01 100.0% 37.2%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.62 47.0 4.30e-01 82.5% 84.5%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.62 48.0 5.11e-01 88.7% 100.0%
4l8eA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 55.0 4.98e-01 100.0% 92.7%
4ivfA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 54.0 4.84e-01 100.0% 90.5%
2d2sA02 1.20.58.1220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain 0.61 54.0 5.04e-01 100.0% 83.2%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 46.0 3.83e-01 100.0% 44.4%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.60 49.0 5.08e-01 93.8% 100.0%
2gsqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 51.0 4.69e-01 100.0% 94.4%
2om6A02 1.10.150.400 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.53 41.0 4.13e-01 93.8% 82.3%
ECOD (68)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5018636 605.1.1.3 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_2 0.86 64.0 6.79e-01 87.5% 88.6%
3603512 633.5.1.1 alpha bundles › Bromodomain-like › LemA-like › LemA-like › LemA 0.84 76.0 6.10e-01 97.5% 100.0%
3634896 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.83 71.0 6.21e-01 91.3% 63.5%
3487846 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.83 71.0 5.70e-01 91.3% 50.3%
3760483 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.83 70.0 5.20e-01 91.3% 38.9%
3564399 3755.3.1.282 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tmemb_cc2 0.82 69.0 6.08e-01 91.3% 64.3%
3213526 192.5.1.14 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA 0.80 68.0 6.17e-01 91.3% 72.4%
3626769 192.5.1.14 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA 0.80 67.0 6.49e-01 91.3% 85.6%
3997627 1075.4.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 0.80 68.0 4.36e-01 92.5% 36.9%
3801044 1075.4.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.80 68.0 3.99e-01 92.5% 21.9%
3928718 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.80 64.0 5.26e-01 91.3% 49.3%
3453933 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.80 67.0 5.98e-01 91.3% 67.3%
4030412 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.79 67.0 5.13e-01 91.3% 43.4%
3503444 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.79 63.0 6.10e-01 91.3% 76.7%
3563649 148.1.3.254 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › KIF21A_4th 0.79 66.0 4.23e-01 91.3% 22.5%
3167235 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.79 65.0 5.14e-01 90.0% 45.6%
3988260 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.78 59.0 3.82e-01 91.3% 19.4%
2337262 1189.1.1.1 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › Trypan_glycop 0.78 70.0 6.57e-01 98.8% 85.6%
3285714 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.78 62.0 5.68e-01 90.0% 65.7%
3497540 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.78 69.0 4.89e-01 100.0% 46.5%
3649030 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.77 70.0 4.81e-01 100.0% 73.3%
3171374 5041.1.1.13 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATG2_CAD 0.77 63.0 5.17e-01 87.5% 52.1%
3695212 601.19.1.18 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Mmc1_C 0.77 63.0 4.20e-01 88.7% 86.3%
3246869 212.1.1.0 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.77 64.0 4.52e-01 91.3% 30.8%
3486748 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.76 68.0 6.21e-01 97.5% 81.9%
3589835 5069.1.3.26 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF1622 0.76 68.0 6.13e-01 100.0% 79.1%
4174467 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.76 59.0 5.73e-01 91.3% 74.4%
3800823 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.75 61.0 5.63e-01 90.0% 67.6%
3201043 604.1.1.132 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › KAR9 0.75 69.0 5.67e-01 100.0% 65.0%
3902100 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.75 60.0 5.94e-01 91.3% 82.4%
3488979 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.75 63.0 5.46e-01 92.5% 88.8%
3467952 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.75 63.0 5.62e-01 91.3% 67.3%
3432902 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.75 67.0 5.94e-01 100.0% 82.6%
3309329 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.75 67.0 4.87e-01 100.0% 51.8%
3258925 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.75 60.0 6.34e-01 88.7% 100.0%
3793986 604.7.1.7 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › Mitofilin 0.75 67.0 5.62e-01 100.0% 80.7%
3792010 604.1.1.105 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1_2 0.74 62.0 5.64e-01 91.3% 68.6%
3221299 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.74 66.0 5.59e-01 100.0% 75.6%
3729252 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 66.0 5.89e-01 100.0% 95.7%
3642682 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.74 67.0 5.91e-01 100.0% 82.6%
3962893 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.74 60.0 5.73e-01 90.0% 76.8%
3686779 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.74 65.0 4.71e-01 100.0% 47.0%
3716423 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.73 57.0 3.69e-01 83.7% 22.0%
3487862 212.1.1.0 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.73 60.0 4.28e-01 91.3% 30.0%
4116779 603.1.1.174 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HisKA 0.73 59.0 6.03e-01 87.5% 93.3%
3221606 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.73 60.0 5.55e-01 91.3% 70.5%
5078218 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.73 60.0 5.04e-01 91.3% 59.3%
4018811 603.1.1.158 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › KAR9 0.73 64.0 5.51e-01 100.0% 70.8%
4086322 5086.1.1.205 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PF30209 0.72 60.0 4.75e-01 91.3% 86.1%
4026662 4207.1.2.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.72 64.0 5.37e-01 100.0% 92.1%
4888150 1075.4.1.9 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane 0.72 60.0 4.00e-01 93.8% 37.6%
4463756 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.72 56.0 5.95e-01 87.5% 97.1%
3600017 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.72 58.0 5.21e-01 90.0% 72.2%
5019215 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.72 57.0 3.84e-01 91.3% 22.6%
4977468 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.71 53.0 5.07e-01 77.5% 72.2%
4016253 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.71 58.0 5.38e-01 91.3% 69.5%
5050887 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 62.0 5.03e-01 100.0% 70.9%
3600894 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.70 63.0 4.62e-01 100.0% 55.7%
4396660 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.70 59.0 4.21e-01 91.3% 94.3%
3180581 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.70 59.0 5.88e-01 93.8% 100.0%
3389928 5054.1.1.59 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.70 63.0 4.79e-01 98.8% 55.0%
3958870 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.70 57.0 5.40e-01 90.0% 92.6%
4027056 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.69 61.0 5.09e-01 98.8% 91.4%
3689709 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.69 58.0 5.08e-01 92.5% 62.5%
4279265 2004.1.1.481 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29 0.66 55.0 3.58e-01 93.8% 29.0%
3590712 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.65 53.0 3.59e-01 91.3% 46.1%
3773794 6170.1.1.25 alpha bundles › Kv7 proximal C-terminal Domain › Kv7 proximal C-terminal Domain › Kv7 proximal C-terminal Domain › PF30874 0.62 50.0 4.95e-01 93.8% 85.9%
3863104 150.5.1.56 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PF30874 0.60 50.0 4.67e-01 93.8% 83.0%
D7 medium residues 522-657
PDB
Domain cluster: representative
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.84 48.0 6.26e-01 72.1% 100.0%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 60.0 6.71e-01 76.5% 100.0%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.80 50.0 5.47e-01 72.1% 74.6%
2ap3A00 1.20.120.570 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like 0.79 67.0 5.90e-01 89.7% 74.0%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 63.0 6.58e-01 83.8% 100.0%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 66.0 6.86e-01 89.0% 100.0%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.78 55.0 5.12e-01 72.8% 83.9%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.77 71.0 5.30e-01 97.8% 86.9%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.77 48.0 5.82e-01 76.5% 94.5%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.77 61.0 5.13e-01 83.8% 85.2%
3kbtA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 69.0 5.45e-01 100.0% 68.3%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 64.0 6.49e-01 90.4% 95.6%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.76 56.0 5.52e-01 77.2% 72.1%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 58.0 6.36e-01 79.4% 100.0%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 56.0 6.15e-01 77.9% 100.0%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.75 41.0 4.69e-01 76.5% 72.0%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.75 54.0 5.32e-01 83.1% 70.6%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 55.0 6.05e-01 76.5% 100.0%
4d8mA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.74 62.0 5.25e-01 88.2% 59.3%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.74 59.0 6.32e-01 89.0% 98.3%
2hz8A00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.74 48.0 5.23e-01 75.0% 78.3%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 46.0 5.64e-01 70.6% 100.0%
2epkX03 1.20.120.670 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › N-acetyl-b-d-glucoasminidase 0.73 56.0 4.72e-01 80.9% 77.7%
3fb2A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 53.0 5.92e-01 75.7% 100.0%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.72 53.0 5.75e-01 75.7% 100.0%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.71 47.0 5.35e-01 73.5% 90.2%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 50.0 5.60e-01 72.1% 100.0%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.71 56.0 5.93e-01 83.1% 96.6%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.71 52.0 5.80e-01 80.9% 99.1%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.71 56.0 5.66e-01 83.1% 100.0%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.70 49.0 5.62e-01 77.2% 100.0%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 47.0 5.53e-01 77.9% 100.0%
3n2oA03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 39.0 4.57e-01 71.3% 78.1%
1dn1B00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 56.0 4.76e-01 89.0% 59.5%
1cgnA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.67 48.0 5.06e-01 77.2% 81.5%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.66 42.0 4.95e-01 77.9% 98.8%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.65 48.0 4.95e-01 75.7% 80.6%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.65 51.0 4.40e-01 80.9% 84.2%
2ix5A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 48.0 4.62e-01 79.4% 67.1%
2rfqC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 48.0 4.47e-01 77.2% 69.7%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.64 46.0 4.76e-01 72.8% 92.1%
5gj7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 48.0 4.65e-01 77.9% 70.2%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 46.0 4.90e-01 77.2% 98.3%
6lw5A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 47.0 3.65e-01 80.1% 50.0%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.61 45.0 5.00e-01 77.2% 99.1%
4y9jA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 44.0 4.35e-01 75.0% 71.1%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.61 39.0 4.19e-01 72.1% 73.7%
3p4tA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 46.0 4.52e-01 80.9% 73.3%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.60 43.0 4.84e-01 75.7% 99.0%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.60 50.0 4.34e-01 89.0% 95.7%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 44.0 4.75e-01 76.5% 99.1%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 42.0 4.60e-01 74.3% 97.3%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.58 43.0 4.51e-01 81.6% 83.5%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 51.0 4.10e-01 97.8% 91.1%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.57 43.0 4.67e-01 79.4% 100.0%
2e9xD01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 41.0 4.15e-01 75.7% 98.5%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3502658 603.1.1.100 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.81 69.0 6.78e-01 90.4% 100.0%
4024992 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.81 72.0 7.08e-01 95.6% 100.0%
3857880 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 64.0 6.25e-01 82.4% 86.2%
3484907 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.80 65.0 6.93e-01 86.0% 100.0%
3890439 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.79 67.0 6.97e-01 89.0% 100.0%
3569017 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.79 68.0 6.41e-01 91.2% 96.9%
3902164 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.79 66.0 6.88e-01 89.0% 100.0%
3534085 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.79 61.0 6.64e-01 81.6% 100.0%
3940793 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.78 59.0 6.39e-01 79.4% 100.0%
4034363 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.77 58.0 6.32e-01 77.2% 100.0%
3201043 604.1.1.132 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › KAR9 0.77 65.0 6.51e-01 90.4% 92.9%
3849331 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.77 60.0 6.42e-01 81.6% 100.0%
3770420 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 64.0 6.68e-01 89.7% 100.0%
3742744 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.75 60.0 6.21e-01 83.1% 98.4%
3629164 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.75 63.0 6.51e-01 89.0% 100.0%
3919843 604.1.1.124 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 0.74 59.0 6.05e-01 83.8% 100.0%
3513988 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.74 61.0 6.40e-01 86.8% 100.0%
3488291 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.74 54.0 6.00e-01 75.0% 100.0%
3988781 604.6.1.63 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF3169 0.73 56.0 5.71e-01 80.1% 91.1%
3755118 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.73 57.0 6.15e-01 82.4% 100.0%
3923407 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.73 55.0 6.05e-01 78.7% 100.0%
3516673 601.33.1.2 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › PPP1R21_helical 0.73 59.0 5.56e-01 86.0% 75.8%
3347027 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.73 64.0 5.46e-01 94.9% 69.8%
3579767 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.73 54.0 5.93e-01 77.9% 100.0%
3589835 5069.1.3.26 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF1622 0.72 53.0 5.81e-01 76.5% 99.1%
4018811 603.1.1.158 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › KAR9 0.72 59.0 6.08e-01 87.5% 99.2%
3488292 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 52.0 5.72e-01 75.0% 100.0%
3885014 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 59.0 6.18e-01 86.8% 100.0%
3628421 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.71 57.0 5.70e-01 84.6% 99.3%
3518321 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 55.0 5.92e-01 81.6% 100.0%
3386489 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.71 55.0 5.15e-01 82.4% 74.7%
3936516 604.8.1.0 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.71 61.0 5.77e-01 94.1% 93.9%
3996707 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 53.0 5.79e-01 78.7% 100.0%
3900969 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.70 55.0 5.87e-01 81.6% 100.0%
3577242 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.70 52.0 5.69e-01 77.9% 100.0%
3779599 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 64.0 4.33e-01 98.5% 52.8%
3535922 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 56.0 5.39e-01 86.0% 77.4%
3933045 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.69 59.0 5.26e-01 91.9% 72.5%
3978381 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 48.0 4.91e-01 79.4% 73.8%
4074827 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.68 57.0 4.58e-01 91.9% 50.4%
3795763 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 62.0 4.15e-01 98.5% 53.3%
4015415 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 56.0 5.17e-01 89.0% 70.9%
4193109 2004.1.1.429 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 0.67 61.0 3.62e-01 98.5% 26.0%
4026662 4207.1.2.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.67 49.0 4.85e-01 75.0% 81.4%
3559937 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 48.0 5.27e-01 74.3% 100.0%
3875112 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.65 58.0 4.32e-01 97.1% 71.8%
4097174 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 59.0 3.76e-01 98.5% 38.1%
3543876 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.62 45.0 4.94e-01 75.7% 96.4%
3883526 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.61 53.0 4.11e-01 95.6% 80.3%
3536875 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.58 51.0 4.02e-01 95.6% 88.8%
5023098 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.57 46.0 4.81e-01 85.3% 100.0%
4950656 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.56 41.0 4.21e-01 75.7% 79.2%
D8 medium residues 658-767_786-800
PDB
Domain cluster: representative
CATH (72)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.81 50.0 4.93e-01 73.6% 58.5%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.80 49.0 5.78e-01 75.2% 88.4%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.78 53.0 5.48e-01 85.6% 73.5%
2ap3A00 1.20.120.570 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like 0.78 61.0 5.27e-01 88.0% 54.2%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.78 54.0 5.13e-01 71.2% 69.9%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.77 57.0 5.18e-01 76.0% 93.1%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.77 45.0 5.00e-01 72.0% 73.5%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.77 54.0 4.50e-01 72.8% 45.5%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.76 54.0 3.96e-01 72.8% 31.4%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.75 56.0 5.04e-01 77.6% 97.6%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.75 59.0 6.36e-01 87.2% 97.2%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.75 48.0 5.72e-01 70.4% 97.6%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.75 59.0 5.01e-01 82.4% 85.6%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 57.0 5.14e-01 81.6% 69.4%
3ofnY00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.74 51.0 5.34e-01 70.4% 86.1%
2d1lA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 52.0 4.08e-01 72.0% 38.2%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 47.0 5.10e-01 93.6% 76.4%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.73 59.0 6.19e-01 88.8% 93.8%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.73 52.0 4.74e-01 72.8% 65.8%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.73 50.0 5.31e-01 77.6% 79.8%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.73 62.0 4.89e-01 90.4% 77.6%
2qe7G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.72 50.0 5.61e-01 71.2% 92.8%
2e87A01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.72 53.0 4.90e-01 83.2% 60.0%
4cemA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.72 47.0 3.49e-01 80.8% 26.7%
3tc1B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.71 54.0 3.94e-01 96.0% 31.8%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 49.0 5.33e-01 88.0% 84.6%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 50.0 5.37e-01 72.8% 89.0%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 46.0 4.87e-01 72.0% 75.0%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.70 45.0 4.89e-01 90.4% 77.7%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 47.0 4.93e-01 76.8% 76.4%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.69 50.0 4.39e-01 74.4% 51.6%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.69 50.0 4.74e-01 92.0% 62.1%
4xt1A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.69 52.0 3.98e-01 90.4% 34.0%
4nswB01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 56.0 4.48e-01 88.0% 65.2%
4wjg400 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.69 59.0 4.61e-01 92.0% 73.9%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.69 47.0 4.88e-01 74.4% 73.9%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.68 51.0 5.46e-01 84.0% 89.9%
3cqcA00 1.20.190.50 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 0.68 62.0 4.96e-01 100.0% 57.5%
7xv3R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.68 48.0 3.76e-01 80.0% 33.9%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 57.0 4.60e-01 90.4% 75.0%
1f1mA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.67 47.0 4.28e-01 71.2% 98.8%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.67 41.0 5.03e-01 70.4% 100.0%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 43.0 4.63e-01 76.8% 75.7%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.67 57.0 4.92e-01 90.4% 85.2%
4mt0A01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.67 62.0 4.36e-01 100.0% 56.3%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.66 55.0 4.84e-01 90.4% 83.5%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.66 48.0 4.60e-01 100.0% 64.2%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.66 45.0 4.60e-01 96.0% 72.3%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 48.0 4.94e-01 91.2% 80.3%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.66 45.0 4.66e-01 93.6% 75.0%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 54.0 4.67e-01 90.4% 78.5%
1z23A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.65 48.0 4.42e-01 76.8% 85.9%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 45.0 4.74e-01 94.4% 80.4%
3k66A01 1.20.120.770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain 0.65 53.0 4.46e-01 88.0% 68.9%
6kd7A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.64 59.0 4.32e-01 100.0% 86.2%
7zdtD01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.64 58.0 4.22e-01 98.4% 94.5%
4d0nB01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.64 50.0 4.04e-01 95.2% 42.9%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.63 40.0 4.42e-01 73.6% 78.4%
3qa8A04 1.20.1270.250 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 53.0 4.36e-01 92.0% 72.1%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 53.0 4.10e-01 90.4% 72.3%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 45.0 4.36e-01 100.0% 68.1%
5gj7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 48.0 4.52e-01 100.0% 67.5%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.61 43.0 4.25e-01 71.2% 96.2%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.60 52.0 4.79e-01 96.0% 75.0%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.59 43.0 4.66e-01 100.0% 92.2%
2a3qA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.59 37.0 3.84e-01 80.0% 67.3%
7rkxR01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.59 54.0 4.21e-01 100.0% 64.3%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.58 42.0 4.43e-01 74.4% 100.0%
7cj3A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.57 53.0 4.11e-01 100.0% 77.5%
1ux5A03 1.20.58.2220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain 0.57 45.0 3.65e-01 84.0% 55.6%
7c4sB01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 50.0 3.88e-01 100.0% 79.7%
1e7pC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.55 42.0 3.38e-01 89.6% 40.2%
ECOD (84)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3214191 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.86 61.0 6.38e-01 73.6% 79.1%
4324499 3755.1.1.3 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › SPAM 0.84 59.0 5.62e-01 72.0% 89.0%
4974110 3755.4.1.91 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › DUF7121 0.83 59.0 4.72e-01 72.8% 63.9%
3350514 3922.1.1.145 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › KIF21A_4th 0.83 58.0 5.29e-01 71.2% 58.1%
5042955 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.83 59.0 3.70e-01 72.8% 23.2%
4569106 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.82 58.0 3.81e-01 72.8% 44.6%
4178099 632.22.1.176 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF27734 0.82 58.0 5.31e-01 72.0% 63.2%
4940230 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.82 58.0 4.77e-01 72.8% 93.8%
4969098 3926.1.1.0 alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D 0.81 58.0 5.08e-01 72.8% 61.7%
4009677 5086.1.1.220 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › phage_tail_N 0.81 58.0 5.01e-01 73.6% 67.0%
3576275 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.81 55.0 5.47e-01 72.8% 66.9%
3634169 4177.1.1.27 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_4 0.81 57.0 4.32e-01 72.8% 35.6%
3718312 604.1.1.118 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GOSR1_N 0.80 62.0 5.86e-01 80.0% 73.8%
4000187 5069.1.3.66 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › 7TM_GPCR_Srw 0.79 56.0 5.66e-01 90.4% 73.2%
4962698 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 55.0 4.80e-01 72.8% 65.9%
3936581 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.78 54.0 4.66e-01 71.2% 50.0%
5029796 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.77 54.0 5.56e-01 72.0% 87.5%
4016292 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.77 55.0 5.40e-01 73.6% 83.0%
3273401 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.77 59.0 4.96e-01 80.0% 72.7%
3275446 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.77 54.0 5.37e-01 72.0% 78.5%
4660205 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.76 65.0 6.33e-01 89.6% 83.7%
3598781 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.76 53.0 4.01e-01 72.0% 32.4%
4468389 5086.1.1.101 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › SH3BP5 0.76 58.0 5.95e-01 79.2% 95.8%
3341646 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.76 53.0 4.03e-01 72.8% 95.5%
3441289 3684.1.1.19 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF1110 0.75 61.0 5.42e-01 85.6% 66.9%
3258119 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.75 54.0 4.37e-01 73.6% 41.3%
3255232 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.74 63.0 4.96e-01 90.4% 67.6%
3211462 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.74 53.0 4.06e-01 72.8% 38.5%
3337008 192.2.1.60 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › KIF21A_4th 0.74 52.0 4.98e-01 71.2% 78.6%
3911413 148.1.3.13 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 0.74 53.0 3.90e-01 83.2% 29.7%
3797517 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 52.0 3.95e-01 72.0% 50.0%
3836689 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.73 52.0 4.87e-01 100.0% 60.7%
3708240 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 57.0 4.62e-01 83.2% 47.7%
3833909 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.72 50.0 4.84e-01 100.0% 63.8%
3517916 2004.1.1.480 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 0.72 56.0 3.83e-01 81.6% 35.5%
3719904 148.1.3.13 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 0.71 53.0 3.75e-01 86.4% 26.2%
3554294 603.2.1.1 alpha bundles › STAT-like › STAT › STAT › STAT_alpha 0.71 57.0 4.87e-01 85.6% 75.0%
3666122 3562.1.1.0 alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 0.71 66.0 6.06e-01 99.2% 82.5%
3267886 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.71 60.0 4.67e-01 90.4% 77.3%
4028291 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.71 58.0 4.00e-01 87.2% 59.3%
3895743 3615.1.1.7 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › CD20 0.71 51.0 4.41e-01 74.4% 98.9%
3517330 603.2.1.1 alpha bundles › STAT-like › STAT › STAT › STAT_alpha 0.70 55.0 4.60e-01 82.4% 77.6%
3470751 3755.3.1.297 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 0.70 59.0 5.42e-01 89.6% 86.3%
3832912 6155.1.1.6 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921 0.69 47.0 3.68e-01 71.2% 33.7%
3806117 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.69 49.0 4.61e-01 100.0% 59.4%
3740499 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.69 58.0 4.76e-01 90.4% 76.0%
3316910 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.69 50.0 4.69e-01 100.0% 61.3%
5076586 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 42.0 4.68e-01 80.8% 77.6%
3931883 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.68 52.0 5.49e-01 88.0% 89.1%
3677974 3939.1.1.207 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › NET2A 0.68 55.0 4.50e-01 85.6% 77.3%
4955064 5086.1.1.233 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF973 0.68 63.0 5.15e-01 100.0% 56.1%
3664290 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.68 44.0 4.11e-01 100.0% 51.6%
3594129 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.67 57.0 4.70e-01 89.6% 81.9%
3436634 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.67 51.0 4.73e-01 100.0% 63.9%
3761638 109.30.1.1 alpha superhelices › Repetitive alpha hairpins › Nucleoporin Nup84/Nup107 › Nucleoporin Nup84/Nup107 › Nup84_Nup100 0.67 60.0 4.56e-01 98.4% 68.1%
3423837 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.67 49.0 4.51e-01 100.0% 59.4%
3963743 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.67 46.0 4.98e-01 84.0% 83.8%
4082395 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.67 48.0 4.20e-01 73.6% 96.7%
3800481 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.67 52.0 4.91e-01 100.0% 68.7%
2394140 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.67 58.0 5.29e-01 99.2% 71.0%
3805395 3291.1.1.119 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › NET2A 0.66 55.0 4.56e-01 88.0% 88.6%
5016617 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.66 55.0 4.26e-01 90.4% 80.7%
3926798 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.66 50.0 4.56e-01 100.0% 60.6%
3924754 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.66 60.0 4.22e-01 100.0% 67.9%
3760811 109.4.1.25 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DIL 0.65 61.0 4.08e-01 99.2% 47.6%
3169497 4323.1.1.1 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.65 52.0 5.14e-01 85.6% 85.2%
3740053 4177.1.1.27 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_4 0.65 54.0 4.23e-01 90.4% 73.0%
3781350 5041.1.1.20 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › PF26669 0.65 46.0 4.77e-01 76.8% 76.7%
4116939 2004.1.1.525 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23, AAA_27, SbcC_Walker_B 0.64 53.0 3.54e-01 88.8% 49.2%
3455444 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.63 51.0 3.60e-01 86.4% 35.9%
3449605 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.63 45.0 4.80e-01 89.6% 85.5%
5070606 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.62 51.0 4.97e-01 100.0% 80.0%
4300897 5094.1.1.1 a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH 0.62 48.0 4.83e-01 83.2% 83.1%
3443462 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.61 45.0 4.68e-01 95.2% 83.5%
3887929 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.61 46.0 4.77e-01 100.0% 82.5%
4013285 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.60 54.0 4.34e-01 98.4% 87.5%
4600893 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.60 50.0 3.98e-01 91.2% 81.2%
3503770 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.59 54.0 5.15e-01 100.0% 84.8%
3975106 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.59 50.0 3.87e-01 92.8% 75.7%
3928099 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.57 52.0 4.12e-01 100.0% 66.3%
3442007 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.57 44.0 4.11e-01 100.0% 64.2%
4466607 109.4.1.1139 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HIR3_TPR_N 0.56 50.0 3.39e-01 99.2% 28.3%
4977934 1076.1.1.0 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related 0.55 42.0 3.40e-01 80.0% 61.7%
3460046 109.62.1.3 alpha superhelices › Repetitive alpha hairpins › AFF4 C-terminal homology domain › AFF4 C-terminal homology domain › THD_CWZF3-5-7 0.53 47.0 3.85e-01 95.2% 70.5%