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NC_018280.1__YP_006560926.1__B622_gp41__00041

Bact-Vir

NC_018280.1__YP_006560926.1__B622_gp41__00041

Identity

Accession:
NC_018280 ↗
Kingdom:
phage

Quality

72.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 330-485
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4nq0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.71 47.0 3.97e-01 71.2% 40.9%
2xevB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 39.0 4.36e-01 96.8% 73.4%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 48.0 5.41e-01 96.8% 99.1%
4flbA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.65 43.0 4.62e-01 93.6% 77.9%
4me2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 39.0 3.68e-01 98.1% 52.1%
1s0pA01 1.25.40.330 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Adenylate cyclase-associated CAP, N-terminal domain 0.58 43.0 4.22e-01 76.9% 90.6%
1jfaB00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 45.0 3.50e-01 84.0% 83.1%
8el7B01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.56 49.0 3.69e-01 92.3% 48.6%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.56 31.0 3.74e-01 86.5% 79.6%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 39.0 4.10e-01 73.7% 90.3%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.54 41.0 4.44e-01 95.5% 96.1%
3au4A01 1.25.40.530 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain 0.53 46.0 4.28e-01 94.2% 81.6%
5ewpA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.53 47.0 4.01e-01 94.9% 68.9%
2chnB03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.51 46.0 4.46e-01 100.0% 91.7%
5mlc900 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.51 34.0 4.01e-01 99.4% 98.1%
8amzT01 1.25.40.990 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 45.0 3.84e-01 99.4% 68.6%
4a5dB00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.50 39.0 3.40e-01 81.4% 65.5%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3684493 109.4.1.213 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FancD2 0.79 57.0 4.29e-01 73.7% 43.1%
3357089 109.4.1.657 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4042 0.70 51.0 3.53e-01 73.7% 35.4%
3936187 109.4.1.472 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RAI16-like 0.69 51.0 4.57e-01 75.6% 85.2%
3238399 109.4.1.1 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 0.67 47.0 5.25e-01 70.5% 100.0%
3822713 109.22.1.1 alpha superhelices › Repetitive alpha hairpins › Survival of motor neuron protein-interacting protein 1 › Survival of motor neuron protein-interacting protein 1 › SIP1 0.67 52.0 4.51e-01 80.1% 70.0%
3439387 109.4.1.359 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.67 48.0 3.70e-01 75.0% 50.0%
3697835 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.66 52.0 3.61e-01 83.3% 79.6%
3515234 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.66 49.0 5.11e-01 98.1% 83.4%
4344287 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 48.0 4.44e-01 74.4% 81.5%
3823978 109.4.1.1736 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30261 0.65 48.0 4.32e-01 97.4% 55.8%
3815354 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 47.0 4.43e-01 94.9% 62.6%
4947815 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.61 33.0 4.00e-01 95.5% 81.0%
3188371 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.60 52.0 4.19e-01 91.0% 89.0%
3687894 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 55.0 3.81e-01 100.0% 94.6%
3320550 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 41.0 3.76e-01 70.5% 76.1%
3195430 109.5.1.1 alpha superhelices › Repetitive alpha hairpins › adenylylcyclase associated protein, CAP-N › adenylylcyclase associated protein, CAP-N › CAP_N 0.59 44.0 4.11e-01 76.9% 84.7%
3734342 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 54.0 3.49e-01 100.0% 48.6%
4014888 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 51.0 4.14e-01 92.9% 79.6%
3621074 109.4.1.353 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MOR2-PAG1_N 0.57 50.0 3.32e-01 96.2% 24.3%
3712740 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 49.0 4.02e-01 93.6% 76.1%
4945390 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.56 41.0 4.45e-01 77.6% 88.9%
3741889 109.4.1.103 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GLE1 0.54 46.0 3.77e-01 91.7% 65.6%
3471361 109.4.1.500 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › LINES_N 0.53 48.0 3.75e-01 97.4% 50.0%
3701766 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.53 40.0 3.83e-01 98.1% 68.3%
3271017 109.4.1.172 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MMS19_C 0.52 47.0 3.21e-01 98.1% 29.3%
3693577 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 43.0 3.89e-01 90.4% 71.8%
3675187 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.51 41.0 3.89e-01 84.0% 91.9%
3264063 109.4.1.103 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GLE1 0.51 44.0 3.45e-01 92.3% 68.2%
3805313 633.6.1.8 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX_C_alpha1 0.50 35.0 3.33e-01 71.2% 97.8%
4951175 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.50 41.0 3.72e-01 99.4% 64.8%
D2 high residues 487-598
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.56 28.0 3.46e-01 95.5% 78.1%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.55 40.0 4.05e-01 75.9% 97.3%
1ui6A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 36.0 3.01e-01 77.7% 39.6%
3lqhA02 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.51 37.0 3.86e-01 77.7% 88.7%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3219385 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 47.0 3.47e-01 94.6% 91.4%
3650115 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.55 41.0 3.61e-01 78.6% 100.0%
3427223 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.53 40.0 3.63e-01 80.4% 100.0%
3917631 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.53 29.0 2.96e-01 93.8% 50.9%
3710139 604.13.1.0 alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like 0.51 36.0 3.50e-01 72.3% 100.0%
3454489 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.51 39.0 3.54e-01 81.2% 79.4%
4676221 1188.1.1.3 alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp 0.51 37.0 3.19e-01 77.7% 84.0%
5041443 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.50 39.0 3.02e-01 85.7% 83.4%
3512636 3930.1.1.6 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › Dicer_PBD 0.50 40.0 4.04e-01 88.4% 100.0%
D3 high residues 617-677
PDB
D4 medium residues 51-119
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3anpB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.76 66.0 4.70e-01 94.2% 87.6%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.74 63.0 4.95e-01 94.2% 91.0%
4kwaB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.74 65.0 4.74e-01 100.0% 65.6%
1aj3A00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 55.0 4.95e-01 82.6% 92.9%
4mo7A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.72 64.0 5.08e-01 100.0% 81.7%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.72 63.0 5.04e-01 100.0% 81.7%
3ccyA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.71 62.0 4.93e-01 100.0% 81.0%
3lwjA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.71 62.0 4.51e-01 98.6% 64.2%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.68 52.0 4.78e-01 81.2% 84.3%
2e8gA01 1.20.1440.150 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.67 51.0 4.28e-01 84.1% 75.8%
2j9wB00 1.20.120.1130 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain 0.67 56.0 4.95e-01 92.8% 67.7%
3fr3B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.66 53.0 4.58e-01 91.3% 73.0%
5xdcB01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.64 51.0 4.42e-01 89.9% 73.9%
4rm7A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.62 52.0 4.36e-01 94.2% 91.0%
3s63A00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.60 45.0 4.18e-01 81.2% 70.5%
1oj6A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 49.0 3.93e-01 94.2% 62.6%
3cueB00 3.30.1380.20 Alpha Beta › 2-Layer Sandwich › Muramoyl-pentapeptide Carboxypeptidase; domain 2 › Trafficking protein particle complex subunit 3 0.59 49.0 3.87e-01 98.6% 76.6%
3b0pA02 1.20.120.1460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.59 43.0 4.27e-01 79.7% 76.0%
3ly7A02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 46.0 3.69e-01 92.8% 59.0%
3qkxB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 47.0 3.66e-01 100.0% 60.2%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.56 44.0 4.08e-01 84.1% 66.7%
3m9vA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.55 44.0 3.78e-01 94.2% 93.7%
7ar7E01 1.10.10.1590 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E 0.55 41.0 4.26e-01 82.6% 100.0%
1jmoA01 3.30.497.10 Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 0.50 44.0 3.11e-01 100.0% 54.2%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4972595 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.70 48.0 4.17e-01 71.0% 96.2%
3909203 109.24.1.2 alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 › DHR-2_Lobe_C 0.70 57.0 4.72e-01 89.9% 94.4%
5039732 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.69 52.0 4.48e-01 82.6% 88.5%
3625019 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 56.0 4.09e-01 94.2% 45.6%
3785071 109.4.1.17 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin 0.67 54.0 4.84e-01 89.9% 84.0%
3932714 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.65 49.0 4.54e-01 81.2% 71.1%
4489939 101.35.1.4 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH3 0.65 48.0 5.08e-01 78.3% 98.3%
4027942 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 54.0 3.24e-01 94.2% 31.1%
3662533 603.1.1.138 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › BPS1 0.65 51.0 4.74e-01 87.0% 96.7%
3823532 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.64 54.0 4.24e-01 92.8% 60.0%
4105244 101.35.1.4 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH3 0.62 48.0 5.08e-01 84.1% 98.3%
5023303 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.62 51.0 4.35e-01 92.8% 71.3%
3923738 5048.1.1.1 alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP 0.61 49.0 3.40e-01 91.3% 65.4%
4504172 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.60 51.0 4.51e-01 98.6% 91.4%
3712805 129.1.1.16 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11 0.60 48.0 3.75e-01 91.3% 80.6%
3838730 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.59 46.0 3.43e-01 84.1% 37.1%
4940814 3896.1.1.0 alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase 0.59 52.0 3.83e-01 98.6% 87.5%
3725482 601.16.1.0 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.59 47.0 3.96e-01 88.4% 85.0%
3686452 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 47.0 4.01e-01 88.4% 85.2%
3953704 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.58 48.0 3.79e-01 92.8% 52.0%
5079275 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.55 44.0 2.75e-01 89.9% 77.3%
5083350 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.55 45.0 3.68e-01 87.0% 69.7%
D5 medium residues 120-212
PDB
Domain cluster: representative
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1tafB00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.76 52.0 5.91e-01 72.0% 92.9%
3ehfD01 1.20.5.1930 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.71 42.0 4.98e-01 82.8% 87.3%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 48.0 4.63e-01 76.3% 75.7%
3b0bB00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.66 48.0 4.77e-01 76.3% 84.5%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 48.0 4.63e-01 77.4% 76.2%
1fouA01 1.10.246.30 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.62 44.0 4.83e-01 100.0% 94.6%
1f45B00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 50.0 4.47e-01 88.2% 98.5%
1ileA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.61 52.0 4.13e-01 93.5% 75.9%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.61 45.0 4.19e-01 77.4% 66.1%
3kflA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.60 50.0 4.12e-01 93.5% 68.0%
2oceA01 1.10.10.650 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › RuvA domain 2-like 0.59 41.0 3.89e-01 72.0% 86.7%
3s4lA00 1.10.3210.30 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › 0.59 48.0 3.82e-01 90.3% 92.9%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 43.0 4.25e-01 77.4% 79.6%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.58 42.0 3.89e-01 76.3% 72.3%
2jlnA00 1.10.4160.10 Mainly Alpha › Orthogonal Bundle › Hydantoin permease › Hydantoin permease 0.57 46.0 2.93e-01 88.2% 52.5%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.56 42.0 4.20e-01 92.5% 77.9%
3kp9A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.56 48.0 4.01e-01 95.7% 53.7%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 47.0 4.25e-01 90.3% 94.5%
2fi1A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 37.0 4.38e-01 83.9% 100.0%
1ks9A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.55 46.0 4.18e-01 91.4% 70.7%
4dvyP01 1.10.357.130 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.55 42.0 3.33e-01 82.8% 99.0%
2b2hA00 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.55 42.0 2.83e-01 83.9% 89.8%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.54 43.0 4.24e-01 87.1% 97.1%
6tqfA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.54 47.0 3.09e-01 96.8% 33.8%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 42.0 3.76e-01 84.9% 66.4%
1k1wA01 3.20.110.20 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › 0.53 41.0 2.77e-01 82.8% 76.4%
2no4A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.53 40.0 4.34e-01 83.9% 98.7%
16vpA00 1.10.1290.10 Mainly Alpha › Orthogonal Bundle › Conserved core of transcriptional regulatory protein vp16 › Alpha trans-inducing (Alpha-TIF) 0.53 46.0 3.23e-01 96.8% 91.6%
2ew2A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.53 44.0 3.91e-01 91.4% 69.4%
2kjgA00 1.20.120.970 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.52 31.0 3.06e-01 84.9% 52.5%
1kz7A01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.52 47.0 3.72e-01 100.0% 92.2%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.51 43.0 4.11e-01 92.5% 95.3%
1zbpA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 34.0 3.56e-01 100.0% 76.5%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3481731 148.1.1.18 alpha arrays › Histone-like › Histone-related › Histone › CENP-S 0.75 52.0 5.15e-01 71.0% 74.7%
3919329 148.1.1.0 alpha arrays › Histone-like › Histone-related › Histone 0.71 49.0 4.54e-01 71.0% 68.7%
4011410 148.1.1.0 alpha arrays › Histone-like › Histone-related › Histone 0.71 51.0 5.39e-01 75.3% 87.1%
4431778 589.1.1.1 alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › Porin chaperone SurA, peptide-binding domain › SurA_N 0.70 52.0 4.05e-01 77.4% 56.2%
4578235 589.1.1.1 alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › Porin chaperone SurA, peptide-binding domain › SurA_N 0.66 51.0 4.13e-01 81.7% 62.4%
3585777 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.66 50.0 3.92e-01 93.5% 38.5%
4979847 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.65 47.0 3.74e-01 76.3% 41.5%
4937529 103.9.1.0 alpha arrays › RuvA-C › RanGAP2 N-terminal domain › RanGAP2 N-terminal domain 0.65 53.0 5.23e-01 88.2% 98.0%
3972335 589.1.1.0 alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › Porin chaperone SurA, peptide-binding domain 0.64 50.0 4.08e-01 81.7% 64.2%
4366393 589.1.1.1 alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › Porin chaperone SurA, peptide-binding domain › SurA_N 0.64 48.0 3.83e-01 78.5% 60.6%
3511227 601.15.1.2 alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › PA28_C 0.64 46.0 3.64e-01 75.3% 51.1%
4962839 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.64 52.0 3.73e-01 89.2% 95.7%
3862143 148.1.1.7 alpha arrays › Histone-like › Histone-related › Histone › TAF 0.63 52.0 4.84e-01 87.1% 80.9%
4964964 5076.2.1.3 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF4013 0.63 50.0 3.90e-01 87.1% 70.5%
3962973 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.62 45.0 3.95e-01 75.3% 88.9%
4331899 1180.1.1.1 alpha bundles › Flagellar biosynthetic protein FliP periplasmic domain › Flagellar biosynthetic protein FliP periplasmic domain › Flagellar biosynthetic protein FliP periplasmic domain › FliP 0.62 42.0 3.61e-01 71.0% 90.3%
5039989 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.61 49.0 4.13e-01 88.2% 78.2%
3964684 1075.1.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › LptF_LptG 0.61 45.0 3.35e-01 79.6% 87.5%
5064195 5076.2.1.0 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ 0.60 42.0 3.59e-01 74.2% 62.5%
3216411 4009.1.1.23 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › C_tripleX 0.60 44.0 4.64e-01 81.7% 85.9%
4931061 2003.1.1.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ELFV_dehydrog 0.59 44.0 3.29e-01 78.5% 90.6%
4983838 592.2.1.0 alpha arrays › PWI domain-like › YugE-like › YugE-like 0.59 49.0 4.79e-01 90.3% 92.0%
3933351 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.58 47.0 3.49e-01 88.2% 61.2%
5014025 1076.1.1.4 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › PrsW-protease 0.58 52.0 3.96e-01 100.0% 64.0%
3669004 611.9.1.0 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain 0.58 43.0 4.54e-01 92.5% 91.3%
4955246 5073.1.3.0 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Potassium-transporting ATPase subunit KdpB transmembrane domain 0.56 47.0 3.57e-01 100.0% 37.8%
4393414 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.56 40.0 3.68e-01 76.3% 56.5%
3400028 3843.1.1.30 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF4781 0.56 47.0 4.86e-01 96.8% 100.0%
4935077 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.56 37.0 3.98e-01 86.0% 84.0%
4938175 4070.1.1.0 alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like 0.55 43.0 3.48e-01 84.9% 84.7%
3396806 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 43.0 4.45e-01 87.1% 91.1%
4075464 603.1.1.129 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › FliP 0.54 42.0 3.26e-01 84.9% 94.0%
3590491 604.39.1.33 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ThrE 0.54 47.0 4.20e-01 98.9% 94.8%
3325278 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.53 47.0 3.80e-01 100.0% 89.7%
3589024 162.1.1.1 alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PRD 0.53 43.0 4.03e-01 89.2% 79.1%
5064861 2006.1.1.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.52 41.0 3.07e-01 87.1% 32.7%
4024723 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.52 46.0 3.60e-01 100.0% 83.4%
3283711 192.29.1.152 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › ABA4-like 0.51 41.0 3.60e-01 83.9% 85.9%
4464634 632.19.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A 0.50 39.0 4.02e-01 86.0% 86.7%
D6 medium residues 213-312
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3o6xA02 1.20.120.1560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.77 56.0 4.86e-01 76.0% 73.6%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.70 51.0 4.66e-01 77.0% 64.2%
1lq7A00 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.67 38.0 4.54e-01 73.0% 83.6%
4ciuA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.67 49.0 3.97e-01 77.0% 81.2%
5d91A02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.66 55.0 4.42e-01 91.0% 60.6%
4akgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.65 53.0 4.51e-01 90.0% 76.2%
3vr4B04 1.10.1140.10 Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 0.57 50.0 4.42e-01 100.0% 84.8%
2ee7A01 1.10.418.10 Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Calponin-like domain 0.56 32.0 3.13e-01 75.0% 47.8%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5068349 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.79 58.0 5.39e-01 75.0% 70.0%
3283711 192.29.1.152 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › ABA4-like 0.74 62.0 5.61e-01 90.0% 83.0%
3493827 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.74 54.0 4.92e-01 76.0% 65.4%
3579981 632.11.1.14 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › TMEM107 0.72 52.0 5.27e-01 76.0% 88.0%
3479952 601.1.2.15 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Frag1 0.71 52.0 4.83e-01 77.0% 80.0%
3606036 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.70 58.0 5.31e-01 90.0% 92.3%
5080179 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.67 55.0 5.41e-01 90.0% 97.3%
3997950 5069.1.3.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › GOST_TM 0.66 49.0 5.15e-01 78.0% 93.3%
3471803 5038.2.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG 0.65 52.0 4.90e-01 88.0% 97.6%
4016252 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.62 47.0 3.79e-01 79.0% 65.8%
3973242 5038.2.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG 0.61 50.0 4.59e-01 94.0% 91.4%
3426161 601.1.2.74 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Rx_N 0.60 48.0 4.50e-01 90.0% 98.5%
3819233 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.58 41.0 3.98e-01 75.0% 94.8%
3227793 5001.1.1.27 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Sre 0.58 50.0 3.62e-01 100.0% 72.7%
3400200 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 48.0 4.48e-01 91.0% 89.6%
5016489 604.39.1.9 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › Vut_1 0.56 49.0 3.99e-01 100.0% 69.5%