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NC_030908.1__YP_009273668.1__BH778_gp43__00043

Bact-Vir

NC_030908.1__YP_009273668.1__BH778_gp43__00043

Identity

Accession:
NC_030908 ↗
Kingdom:
phage

Quality

86.6 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Casadabanvirus› Pseudomonas_phage_JBD69

TaxID: 1777053

Cluster

View cluster (351 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 9-149
PDB
Domain cluster: rep: MT764210__UXF49854.1__7841G1D8-26__00026__D257-398
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF23840.2 best Phage_tail_terminator 133.3 9.20e-39 100.0% 91.2%
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gjvA00 3.30.2000.10 Alpha Beta › 2-Layer Sandwich › STM4215-like › Phage tail protein-like 0.86 74.0 7.59e-01 100.0% 92.6%
4acvA00 3.30.2000.30 Alpha Beta › 2-Layer Sandwich › STM4215-like › 0.84 65.0 7.02e-01 100.0% 93.3%
3fz2A00 3.30.70.1700 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Phage minor tail protein U 0.80 66.0 6.95e-01 100.0% 96.1%
6toaF01 3.30.2000.30 Alpha Beta › 2-Layer Sandwich › STM4215-like › 0.79 69.0 7.16e-01 99.3% 97.7%
4hudA01 3.30.2000.40 Alpha Beta › 2-Layer Sandwich › STM4215-like › Myoviridae tail sheath stabiliser 0.73 68.0 5.89e-01 100.0% 79.0%
2l25A00 3.30.2000.20 Alpha Beta › 2-Layer Sandwich › STM4215-like › 0.70 62.0 6.27e-01 100.0% 95.0%
3pcoB06 3.30.70.380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ferrodoxin-fold anticodon-binding domain 0.70 39.0 4.72e-01 83.7% 83.0%
2rb7A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 39.0 4.36e-01 92.9% 72.0%
1cg2A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 40.0 4.52e-01 87.2% 75.5%
5xoyB02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 38.0 4.35e-01 92.9% 73.8%
2y3uA02 3.30.980.50 Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › 0.67 46.0 5.00e-01 100.0% 86.7%
2x8kA01 2.40.30.200 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.66 44.0 5.02e-01 98.6% 90.5%
3ct9A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 38.0 4.25e-01 86.5% 72.9%
4q7aC02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 38.0 4.30e-01 92.9% 74.1%
2qtpA00 3.30.1330.110 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › BB2672 0.61 44.0 4.37e-01 73.8% 100.0%
2i4lA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.61 55.0 4.16e-01 99.3% 80.9%
5k8mA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 40.0 4.16e-01 91.5% 71.0%
3w1eA02 3.40.50.10610 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ABC-type transport auxiliary lipoprotein component 0.60 43.0 3.96e-01 100.0% 57.6%
1sesA02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.60 54.0 4.15e-01 99.3% 71.4%
3tx8A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 37.0 4.02e-01 86.5% 74.6%
3ialA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.60 54.0 4.31e-01 99.3% 78.6%
3lssA02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.60 53.0 4.09e-01 98.6% 70.9%
3lvtA03 2.60.40.2210 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 37.0 3.90e-01 92.9% 70.5%
6h9xA02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.58 52.0 4.01e-01 100.0% 70.6%
2cjaA02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.57 51.0 3.96e-01 99.3% 78.1%
6h05A00 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.57 42.0 3.51e-01 75.9% 79.7%
2e5aA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.57 47.0 3.92e-01 87.2% 76.3%
4divV01 2.40.30.200 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.57 47.0 4.78e-01 95.7% 91.2%
1httA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.57 51.0 4.13e-01 98.6% 90.3%
3od1A01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.57 51.0 3.93e-01 99.3% 92.2%
2pmeA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.56 50.0 3.89e-01 97.9% 83.8%
3qkbA00 3.30.110.70 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Hypothetical protein apc22750. Chain B 0.56 36.0 4.30e-01 90.1% 96.8%
6pqhA02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.56 50.0 3.67e-01 97.2% 89.7%
3i4hX01 3.30.70.1890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 39.0 4.09e-01 88.7% 79.7%
3l4gC04 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.56 50.0 4.06e-01 100.0% 93.1%
2xgtA02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.55 50.0 3.81e-01 99.3% 88.5%
1yfsA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.55 49.0 4.15e-01 97.9% 97.4%
1vqzA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.55 45.0 3.78e-01 87.9% 80.6%
3netB01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.55 50.0 3.84e-01 100.0% 92.7%
3bf2A00 3.30.160.150 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain 0.54 35.0 3.67e-01 100.0% 71.2%
3gb0A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 37.0 4.03e-01 90.1% 85.7%
4n4rB00 3.30.160.150 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain 0.53 35.0 3.50e-01 100.0% 63.6%
2ddzE00 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.52 42.0 3.88e-01 88.7% 82.1%
4lesA00 2.60.40.1240 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 40.0 4.09e-01 100.0% 83.8%
3byqA00 3.30.1330.110 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › BB2672 0.51 41.0 3.77e-01 87.2% 88.0%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5454 304.124.1.2 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like › Gp37 0.86 74.0 7.64e-01 100.0% 94.0%
3966645 304.124.1.0 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like 0.84 70.0 7.47e-01 97.9% 98.4%
4883824 304.124.1.6 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like › DUF5072 0.83 66.0 6.90e-01 100.0% 89.9%
5004177 304.124.1.3 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like › DUF3168 0.81 68.0 7.22e-01 99.3% 98.4%
4291659 304.124.1.8 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like › Phage_Mu_Gp37 0.80 73.0 7.39e-01 99.3% 95.7%
5083619 304.124.1.0 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like 0.79 73.0 7.30e-01 100.0% 95.8%
364035 304.124.1.1 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like › Phage_tail_U 0.78 66.0 6.82e-01 100.0% 95.5%
4928893 304.124.1.0 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like 0.77 72.0 7.20e-01 100.0% 95.9%
3964886 304.124.1.0 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like 0.77 71.0 7.15e-01 97.9% 97.9%
5078308 304.124.1.0 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like 0.75 66.0 6.82e-01 100.0% 96.3%
5040945 304.124.1.0 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like 0.75 70.0 6.90e-01 100.0% 92.7%
4261744 304.124.1.0 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like 0.74 62.0 6.59e-01 99.3% 99.2%
4954550 310.3.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.73 54.0 5.87e-01 99.3% 93.0%
5083880 304.124.1.0 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like 0.71 66.0 6.59e-01 100.0% 97.9%
3948250 304.124.1.9 ↗ a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like › Phage_tail_terminator_9 0.69 65.0 6.26e-01 100.0% 92.3%
4562028 310.3.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.67 49.0 4.94e-01 99.3% 74.5%
4943141 304.25.1.0 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.64 40.0 4.35e-01 91.5% 73.3%
4970983 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.64 41.0 4.42e-01 91.5% 75.0%
4935602 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.62 39.0 4.22e-01 92.2% 73.3%
3279708 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.61 38.0 4.14e-01 92.2% 73.9%
4163084 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.61 37.0 4.06e-01 92.9% 73.0%
4136515 310.3.1.23 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related › RP854 0.60 49.0 4.71e-01 100.0% 76.2%
4015715 314.1.1.0 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases 0.60 54.0 4.09e-01 98.6% 72.2%
4423196 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.60 54.0 4.04e-01 99.3% 67.8%
3187981 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.60 54.0 3.98e-01 100.0% 71.6%
5049458 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.60 53.0 4.32e-01 96.5% 96.2%
4357473 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.59 54.0 3.96e-01 99.3% 74.9%
3643481 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 39.0 2.86e-01 85.8% 24.2%
4113613 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.59 54.0 4.09e-01 99.3% 71.4%
4973362 314.1.1.0 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases 0.59 54.0 4.06e-01 99.3% 70.9%
4273807 314.1.1.0 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases 0.59 54.0 3.79e-01 100.0% 58.4%
4933257 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.59 54.0 4.09e-01 100.0% 76.1%
4427499 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.59 53.0 4.10e-01 99.3% 72.1%
3592320 304.25.1.0 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.59 41.0 4.20e-01 90.8% 72.9%
5078236 304.51.1.9 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas6_N 0.59 43.0 4.60e-01 87.9% 87.2%
3289660 305.1.1.3 ↗ a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › DUF3000 0.58 41.0 4.35e-01 77.3% 84.2%
5071358 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.58 40.0 4.14e-01 86.5% 76.2%
5000855 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.58 52.0 3.87e-01 100.0% 71.5%
3336425 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 37.0 3.78e-01 90.1% 65.9%
3959045 305.1.1.0 ↗ a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase 0.58 40.0 4.31e-01 77.3% 84.2%
3591994 304.103.1.0 ↗ a+b two layers › Alpha-beta plaits › FMN-dependent nitroreductase-like › FMN-dependent nitroreductase-like 0.57 51.0 4.59e-01 95.7% 93.7%
3387344 7503.1.1.4 ↗ a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › LptE 0.56 36.0 3.61e-01 100.0% 62.8%
3163625 7503.1.1.4 ↗ a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › LptE 0.55 36.0 3.61e-01 100.0% 63.4%
3302845 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 36.0 3.74e-01 89.4% 70.0%
4992019 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.54 42.0 4.23e-01 92.9% 80.0%
3495018 11.12.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like 0.54 40.0 3.50e-01 92.2% 50.0%
3974994 7503.1.1.4 ↗ a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › LptE 0.54 36.0 3.40e-01 100.0% 55.9%
5027995 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.54 41.0 3.50e-01 80.9% 86.8%
2404731 11.12.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD 0.52 39.0 3.39e-01 91.5% 49.3%
3963954 7503.1.1.4 ↗ a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › LptE 0.52 34.0 3.45e-01 100.0% 64.8%
3699878 12.1.1.94 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › DUF4139 0.52 41.0 4.33e-01 89.4% 94.4%
3707804 11.1.5.59 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › DUF4139 0.51 41.0 3.92e-01 89.4% 73.1%
4950751 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.51 38.0 3.82e-01 92.2% 76.4%
3975946 11.1.5.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › Fimbrial 0.51 37.0 3.49e-01 75.9% 90.6%
3965192 1.1.13.67 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › DUF2460 0.51 38.0 4.19e-01 92.9% 99.1%
3208004 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.51 40.0 2.63e-01 85.1% 22.8%
3259575 225.1.1.3 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.50 46.0 4.24e-01 100.0% 97.2%
5018915 225.1.1.3 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.50 45.0 4.39e-01 100.0% 96.9%
3596254 304.25.1.0 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.50 35.0 3.73e-01 87.2% 81.6%