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NC_030923.1__YP_009275020.1__BH776_gp02__00002
Bact-VirNC_030923.1__YP_009275020.1__BH776_gp02__00002
Identity
- Accession:
- NC_030923 ↗
- Kingdom:
- phage
Quality
70.7
mean pLDDT
Taxonomy
Heunggongvirae›
Uroviricota›
Caudoviricetes›
Autographivirales›
Autoscriptoviridae›
Kantovirus›
Pseudomonas_phage_YMC11/06/C171_PPU_BP
TaxID: 1777063
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 91-188
Domain cluster:
representative
CATH (56)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.85 | 74.0 | 6.90e-01 | 91.8% | 100.0% |
| 3fblA00 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.81 | 54.0 | 5.86e-01 | 79.6% | 80.5% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.77 | 65.0 | 6.58e-01 | 90.8% | 94.8% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.76 | 61.0 | 5.91e-01 | 86.7% | 76.4% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.76 | 67.0 | 6.01e-01 | 95.9% | 97.7% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.72 | 58.0 | 5.71e-01 | 93.9% | 80.2% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.72 | 57.0 | 5.14e-01 | 85.7% | 77.0% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.69 | 59.0 | 5.08e-01 | 93.9% | 65.2% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.69 | 58.0 | 4.57e-01 | 89.8% | 84.6% |
| 5j1gA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 62.0 | 4.75e-01 | 100.0% | 88.6% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.67 | 53.0 | 4.62e-01 | 84.7% | 94.6% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 58.0 | 5.71e-01 | 95.9% | 98.1% |
| 5nx5B00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.67 | 55.0 | 3.93e-01 | 89.8% | 39.0% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.67 | 57.0 | 4.51e-01 | 92.9% | 49.0% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 54.0 | 5.29e-01 | 87.8% | 84.3% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 57.0 | 4.68e-01 | 92.9% | 76.9% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.66 | 53.0 | 4.46e-01 | 87.8% | 68.7% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 50.0 | 3.77e-01 | 80.6% | 80.5% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.65 | 50.0 | 5.30e-01 | 81.6% | 94.3% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 48.0 | 4.73e-01 | 79.6% | 100.0% |
| 2hytA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 54.0 | 4.40e-01 | 94.9% | 56.5% |
| 4a5dB00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.63 | 53.0 | 4.03e-01 | 90.8% | 80.6% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.63 | 51.0 | 4.97e-01 | 87.8% | 96.3% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.63 | 48.0 | 4.37e-01 | 92.9% | 60.8% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.63 | 51.0 | 4.10e-01 | 88.8% | 78.1% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.63 | 50.0 | 4.06e-01 | 88.8% | 45.2% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.62 | 55.0 | 4.31e-01 | 99.0% | 52.8% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 56.0 | 4.29e-01 | 100.0% | 55.4% |
| 1oj6A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.62 | 50.0 | 4.36e-01 | 86.7% | 96.6% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.62 | 52.0 | 4.13e-01 | 92.9% | 48.3% |
| 2oi8A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 50.0 | 4.00e-01 | 88.8% | 42.9% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.61 | 47.0 | 4.27e-01 | 87.8% | 60.3% |
| 5kbwB00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.61 | 52.0 | 4.33e-01 | 92.9% | 83.0% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 50.0 | 5.11e-01 | 92.9% | 96.9% |
| 1cg5B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 47.0 | 4.18e-01 | 83.7% | 92.9% |
| 3m9vA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.60 | 44.0 | 4.06e-01 | 77.6% | 60.6% |
| 2iakA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 51.0 | 4.17e-01 | 99.0% | 86.5% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.58 | 48.0 | 4.97e-01 | 93.9% | 96.7% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 40.0 | 4.43e-01 | 81.6% | 97.3% |
| 1eq1A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.57 | 48.0 | 4.13e-01 | 94.9% | 59.6% |
| 2f2gA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.57 | 44.0 | 3.45e-01 | 82.7% | 67.9% |
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.57 | 48.0 | 3.19e-01 | 92.9% | 74.3% |
| 2om6A02 | 1.10.150.400 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.57 | 36.0 | 3.96e-01 | 70.4% | 79.7% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.56 | 41.0 | 3.86e-01 | 77.6% | 62.9% |
| 1o82A00 | 1.20.225.10 | Mainly Alpha › Up-down Bundle › Bacteriocin As-48; Chain A › Bacteriocin AS-48 | 0.56 | 33.0 | 3.75e-01 | 77.6% | 80.0% |
| 7smtA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.56 | 46.0 | 3.95e-01 | 94.9% | 86.2% |
| 7lb8B01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.56 | 47.0 | 3.26e-01 | 90.8% | 86.8% |
| 1h2uA01 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 45.0 | 3.31e-01 | 87.8% | 54.2% |
| 1c02A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.55 | 48.0 | 4.06e-01 | 95.9% | 65.1% |
| 8jpdG01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.55 | 37.0 | 3.31e-01 | 78.6% | 47.6% |
| 2rkkA01 | 1.25.40.270 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 | 0.54 | 41.0 | 3.61e-01 | 87.8% | 51.9% |
| 2fm8C01 | 1.10.4150.10 | Mainly Alpha › Orthogonal Bundle › SipA N-terminal domain-like › SipA N-terminal domain-like | 0.54 | 43.0 | 3.48e-01 | 88.8% | 72.7% |
| 6dlzA01 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.53 | 46.0 | 3.83e-01 | 99.0% | 81.8% |
| 1bbhA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.52 | 43.0 | 3.87e-01 | 87.8% | 84.7% |
| 3purA03 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 43.0 | 4.19e-01 | 92.9% | 90.0% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.50 | 41.0 | 3.40e-01 | 89.8% | 90.1% |
ECOD (68)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3257510 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.86 | 70.0 | 6.02e-01 | 90.8% | 57.2% |
| 4399510 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.83 | 77.0 | 5.86e-01 | 100.0% | 52.6% |
| 4624818 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.81 | 67.0 | 7.02e-01 | 88.8% | 100.0% |
| 3656707 | 3236.1.1.1 ↗ | alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger | 0.81 | 66.0 | 4.21e-01 | 90.8% | 19.1% |
| 4018207 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.79 | 72.0 | 5.98e-01 | 98.0% | 86.7% |
| 4530958 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.77 | 70.0 | 4.65e-01 | 100.0% | 26.4% |
| 3289364 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.76 | 66.0 | 5.65e-01 | 92.9% | 96.0% |
| 4565834 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.76 | 63.0 | 5.43e-01 | 88.8% | 95.3% |
| 3291430 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.76 | 63.0 | 5.59e-01 | 89.8% | 100.0% |
| 4026680 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.75 | 68.0 | 5.25e-01 | 100.0% | 50.7% |
| 3279566 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.75 | 68.0 | 5.82e-01 | 98.0% | 96.7% |
| 3289554 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.75 | 61.0 | 5.73e-01 | 87.8% | 100.0% |
| 3955107 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.74 | 64.0 | 5.49e-01 | 93.9% | 96.8% |
| 4323122 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.74 | 67.0 | 4.35e-01 | 100.0% | 22.5% |
| 4080313 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.73 | 66.0 | 5.89e-01 | 100.0% | 100.0% |
| 3297600 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.73 | 65.0 | 6.54e-01 | 98.0% | 100.0% |
| 4988301 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.73 | 62.0 | 5.33e-01 | 90.8% | 100.0% |
| 3580470 | 4044.1.1.15 ↗ | alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › EMC6 | 0.73 | 64.0 | 5.94e-01 | 93.9% | 78.3% |
| 3792754 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.73 | 64.0 | 5.83e-01 | 93.9% | 75.2% |
| 4953680 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.72 | 61.0 | 4.51e-01 | 92.9% | 35.1% |
| 4029940 | 604.5.1.44 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › EMC6 | 0.72 | 62.0 | 6.34e-01 | 95.9% | 100.0% |
| 3442159 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.72 | 46.0 | 4.68e-01 | 100.0% | 66.3% |
| 3283395 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.72 | 64.0 | 5.50e-01 | 98.0% | 96.8% |
| 3850891 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.71 | 57.0 | 5.10e-01 | 87.8% | 82.9% |
| 4554328 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.70 | 56.0 | 5.89e-01 | 87.8% | 95.5% |
| 5079588 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.69 | 56.0 | 5.77e-01 | 87.8% | 100.0% |
| 4929490 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.69 | 55.0 | 5.65e-01 | 88.8% | 100.0% |
| 5014971 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.69 | 58.0 | 4.52e-01 | 91.8% | 52.6% |
| 3479092 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.68 | 56.0 | 5.66e-01 | 89.8% | 93.0% |
| 4984051 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.68 | 61.0 | 4.69e-01 | 98.0% | 80.9% |
| 4983399 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.68 | 55.0 | 4.44e-01 | 88.8% | 49.7% |
| 5083938 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.67 | 55.0 | 4.47e-01 | 89.8% | 57.4% |
| 3725456 | 604.3.1.24 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › PF27980 | 0.67 | 53.0 | 5.66e-01 | 83.7% | 100.0% |
| 3940580 | 604.6.1.14 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › RasGAP_C | 0.67 | 56.0 | 5.28e-01 | 89.8% | 86.1% |
| 4024626 | 545.1.2.2 ↗ | alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Sporozoite protein UIS3 soluble domain › ETRAMP | 0.67 | 54.0 | 4.73e-01 | 88.8% | 58.6% |
| 4592728 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.67 | 54.0 | 5.61e-01 | 87.8% | 97.8% |
| 3812703 | 3758.1.1.7 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › BPS1 | 0.67 | 59.0 | 4.51e-01 | 96.9% | 61.0% |
| 4618102 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.66 | 51.0 | 5.55e-01 | 86.7% | 100.0% |
| 3981661 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 54.0 | 5.58e-01 | 88.8% | 95.6% |
| 3574413 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.66 | 48.0 | 4.98e-01 | 84.7% | 83.3% |
| 5051571 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.66 | 54.0 | 4.27e-01 | 87.8% | 75.9% |
| 3180975 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.65 | 60.0 | 4.77e-01 | 100.0% | 84.7% |
| 5045531 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.65 | 47.0 | 5.00e-01 | 78.6% | 87.1% |
| 4032384 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.65 | 50.0 | 5.39e-01 | 88.8% | 100.0% |
| 5082279 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 52.0 | 4.86e-01 | 86.7% | 79.2% |
| 3579522 | 604.1.1.98 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1 | 0.65 | 53.0 | 5.18e-01 | 87.8% | 93.3% |
| 4927650 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.65 | 50.0 | 3.69e-01 | 82.7% | 70.8% |
| 3393646 | 102.1.3.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain | 0.63 | 49.0 | 4.57e-01 | 81.6% | 75.0% |
| 4236831 | 604.6.1.50 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF2524 | 0.63 | 48.0 | 5.17e-01 | 80.6% | 100.0% |
| 3883670 | 604.1.1.7 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 | 0.63 | 54.0 | 5.03e-01 | 93.9% | 94.2% |
| 5064482 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.62 | 46.0 | 3.80e-01 | 76.5% | 99.4% |
| 3584048 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 45.0 | 4.68e-01 | 81.6% | 83.3% |
| 3228341 | 604.1.1.55 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › RasGAP_C | 0.62 | 52.0 | 4.99e-01 | 92.9% | 84.3% |
| 4963648 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.62 | 42.0 | 2.68e-01 | 70.4% | 15.1% |
| 4370184 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.61 | 52.0 | 4.30e-01 | 94.9% | 90.2% |
| 3692081 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.61 | 48.0 | 4.12e-01 | 82.7% | 100.0% |
| 3336125 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.61 | 47.0 | 3.94e-01 | 81.6% | 56.5% |
| 3578534 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.61 | 55.0 | 5.39e-01 | 99.0% | 95.2% |
| 4013665 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.61 | 53.0 | 4.45e-01 | 99.0% | 65.1% |
| 4019479 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.60 | 54.0 | 3.76e-01 | 100.0% | 88.1% |
| 4981575 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.58 | 46.0 | 4.16e-01 | 84.7% | 68.1% |
| 1144728 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.58 | 44.0 | 4.54e-01 | 85.7% | 86.2% |
| 5028679 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.57 | 44.0 | 4.42e-01 | 82.7% | 81.6% |
| 3316280 | 3718.1.1.13 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › KNOX1, KNOX2 | 0.57 | 50.0 | 4.70e-01 | 92.9% | 84.3% |
| 3734058 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.57 | 47.0 | 4.59e-01 | 87.8% | 85.7% |
| 3348566 | 3291.1.1.106 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Chloroplast_duf | 0.56 | 44.0 | 3.87e-01 | 82.7% | 99.3% |
| 3740842 | 604.12.1.9 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT2 | 0.56 | 46.0 | 4.57e-01 | 90.8% | 86.0% |
| 4993063 | 606.1.1.0 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain | 0.54 | 47.0 | 4.36e-01 | 93.9% | 75.8% |
D2
high
residues 383-520
Domain cluster:
representative
CATH (47)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2b6cA02 | 1.25.40.290 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat domains | 0.68 | 44.0 | 5.14e-01 | 82.6% | 92.8% |
| 4g10A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.65 | 47.0 | 4.75e-01 | 76.1% | 75.0% |
| 4gyoB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 38.0 | 3.86e-01 | 77.5% | 57.6% |
| 3rkvA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.64 | 41.0 | 4.04e-01 | 73.9% | 59.2% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.64 | 43.0 | 4.78e-01 | 78.3% | 87.2% |
| 3lxzB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 46.0 | 4.61e-01 | 78.3% | 74.6% |
| 2ycdA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 42.0 | 4.48e-01 | 79.0% | 78.6% |
| 4hz4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 39.0 | 4.31e-01 | 81.2% | 76.8% |
| 5a4uF02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 45.0 | 4.75e-01 | 76.1% | 84.3% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 40.0 | 4.03e-01 | 77.5% | 62.5% |
| 2mhkA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 37.0 | 3.92e-01 | 83.3% | 64.8% |
| 3c8eA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 46.0 | 4.39e-01 | 78.3% | 67.5% |
| 3k7xA00 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.61 | 46.0 | 3.40e-01 | 89.9% | 30.8% |
| 7fhyB01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.60 | 51.0 | 3.92e-01 | 89.1% | 49.5% |
| 1e2aA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 41.0 | 4.74e-01 | 73.9% | 97.1% |
| 4u72A01 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 49.0 | 4.19e-01 | 89.1% | 81.5% |
| 8carA01 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.59 | 49.0 | 3.56e-01 | 88.4% | 41.8% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.58 | 36.0 | 3.82e-01 | 76.8% | 70.6% |
| 5gxxA01 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.58 | 45.0 | 3.21e-01 | 93.5% | 26.6% |
| 1yz5B00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.57 | 49.0 | 4.19e-01 | 93.5% | 76.4% |
| 3peuB00 | 1.25.40.510 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › GLE1-like | 0.57 | 52.0 | 4.08e-01 | 100.0% | 82.7% |
| 2ahfA00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.57 | 49.0 | 3.53e-01 | 90.6% | 37.9% |
| 3qc1A01 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.57 | 44.0 | 4.34e-01 | 81.9% | 85.4% |
| 5h41A01 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.57 | 46.0 | 3.22e-01 | 84.8% | 47.1% |
| 2csxA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.57 | 44.0 | 4.17e-01 | 84.1% | 68.7% |
| 1yw0A00 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 45.0 | 3.78e-01 | 86.2% | 75.7% |
| 3rk6A00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 50.0 | 4.32e-01 | 97.8% | 74.7% |
| 4flbA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 49.0 | 5.01e-01 | 95.7% | 100.0% |
| 8fnyA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 33.0 | 2.95e-01 | 83.3% | 39.3% |
| 3renA00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.56 | 45.0 | 3.41e-01 | 91.3% | 35.6% |
| 2okxA05 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.56 | 46.0 | 3.49e-01 | 89.9% | 42.2% |
| 5zigA00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.55 | 46.0 | 3.31e-01 | 89.9% | 36.9% |
| 7ae2A01 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.55 | 39.0 | 3.99e-01 | 73.9% | 85.4% |
| 1wzzA00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.55 | 45.0 | 3.42e-01 | 87.7% | 39.2% |
| 4jgwA02 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.54 | 44.0 | 3.73e-01 | 87.7% | 82.5% |
| 2eabA02 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.54 | 49.0 | 3.32e-01 | 100.0% | 46.4% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.54 | 30.0 | 3.74e-01 | 76.8% | 90.4% |
| 1qqtA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.53 | 41.0 | 4.14e-01 | 83.3% | 80.4% |
| 3bqoA00 | 1.25.40.210 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain | 0.53 | 42.0 | 3.67e-01 | 82.6% | 60.4% |
| 3ejnA01 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 42.0 | 3.71e-01 | 82.6% | 71.6% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.53 | 38.0 | 3.91e-01 | 79.0% | 78.5% |
| 3fhnA04 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.52 | 37.0 | 3.79e-01 | 73.2% | 94.7% |
| 3aqtA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 44.0 | 4.00e-01 | 97.8% | 89.7% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.50 | 36.0 | 3.95e-01 | 76.1% | 93.5% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.50 | 36.0 | 3.89e-01 | 74.6% | 89.1% |
| 3cqcA00 | 1.20.190.50 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › | 0.50 | 43.0 | 3.61e-01 | 94.9% | 96.8% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.50 | 36.0 | 3.76e-01 | 75.4% | 85.5% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3709066 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 41.0 | 4.18e-01 | 78.3% | 67.1% |
| 3722615 | 3924.1.1.0 ↗ | alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 | 0.60 | 50.0 | 4.48e-01 | 87.0% | 85.9% |
| 1196766 | 109.1.1.6 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_2 | 0.60 | 44.0 | 4.47e-01 | 76.1% | 76.6% |
| 4976763 | 109.2.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid | 0.59 | 47.0 | 3.45e-01 | 86.2% | 48.9% |
| 5013136 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 48.0 | 3.90e-01 | 87.7% | 65.1% |
| 3731666 | 109.4.1.292 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF3a_PCI_TPR-like | 0.58 | 50.0 | 3.58e-01 | 95.7% | 56.6% |
| 4056054 | 604.10.1.1 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA | 0.58 | 42.0 | 4.66e-01 | 77.5% | 94.5% |
| 3187659 | 622.1.1.2 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HsbA | 0.58 | 45.0 | 4.34e-01 | 81.2% | 82.6% |
| 5021529 | 604.39.1.9 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › Vut_1 | 0.58 | 47.0 | 4.10e-01 | 87.0% | 81.0% |
| 3403606 | 109.4.1.2420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28853, PF28855 | 0.57 | 47.0 | 3.37e-01 | 87.0% | 52.2% |
| 3613544 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 43.0 | 3.71e-01 | 84.1% | 50.2% |
| 4504902 | 3222.1.1.1 ↗ | a+b complex topology › Regulatory domain of isocitrate dehydrogenase kinase/phosphatase › Regulatory domain of isocitrate dehydrogenase kinase/phosphatase › Regulatory domain of isocitrate dehydrogenase kinase/phosphatase › AceK_regulatory | 0.57 | 40.0 | 3.09e-01 | 71.0% | 98.4% |
| 4143412 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 51.0 | 3.75e-01 | 100.0% | 76.6% |
| 3406149 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 45.0 | 3.69e-01 | 84.8% | 81.2% |
| 4864598 | 109.4.1.223 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Aquarius_N_1st | 0.56 | 51.0 | 3.77e-01 | 100.0% | 95.3% |
| 4015821 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 49.0 | 3.83e-01 | 94.9% | 75.9% |
| 3268439 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 41.0 | 3.73e-01 | 83.3% | 55.8% |
| 3788590 | 109.4.1.464 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exportin-T | 0.55 | 47.0 | 3.88e-01 | 94.2% | 72.3% |
| 4547093 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 49.0 | 3.36e-01 | 97.8% | 56.7% |
| 3631635 | 109.24.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 › DHR-2_Lobe_A | 0.54 | 40.0 | 4.18e-01 | 93.5% | 83.8% |
| 3608905 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 46.0 | 3.48e-01 | 91.3% | 47.5% |
| 4017705 | 109.24.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 | 0.53 | 42.0 | 4.25e-01 | 97.8% | 84.3% |
| 3683441 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 44.0 | 3.73e-01 | 90.6% | 91.9% |
| 3925864 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 48.0 | 4.13e-01 | 100.0% | 92.6% |
| 3671005 | 611.3.1.0 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.52 | 40.0 | 4.12e-01 | 81.2% | 88.1% |
| 3318639 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 46.0 | 3.95e-01 | 100.0% | 84.4% |
D3
medium
residues 214-305
Domain cluster:
representative
CATH (49)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3l0mA02 | 1.20.1280.280 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.86 | 60.0 | 6.43e-01 | 71.7% | 100.0% |
| 2jpnA00 | 1.20.1280.210 | Mainly Alpha › Up-down Bundle › Monooxygenase › Uncharacterised protein UvsW.1 | 0.78 | 59.0 | 6.30e-01 | 78.3% | 92.4% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 52.0 | 5.21e-01 | 71.7% | 100.0% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.74 | 54.0 | 5.08e-01 | 77.2% | 100.0% |
| 2k0nA00 | 1.10.246.20 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain | 0.73 | 40.0 | 4.20e-01 | 94.6% | 58.8% |
| 2qsbA00 | 1.20.1440.50 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like | 0.72 | 48.0 | 4.97e-01 | 71.7% | 72.9% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.72 | 52.0 | 5.02e-01 | 76.1% | 77.4% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.71 | 53.0 | 4.71e-01 | 79.3% | 82.2% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 51.0 | 4.99e-01 | 77.2% | 96.0% |
| 2vtyA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.69 | 47.0 | 4.03e-01 | 71.7% | 44.4% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.68 | 52.0 | 4.03e-01 | 80.4% | 88.5% |
| 6fu4A01 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.67 | 57.0 | 4.65e-01 | 90.2% | 55.2% |
| 6tqpA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.67 | 57.0 | 5.02e-01 | 93.5% | 63.2% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.67 | 47.0 | 4.47e-01 | 73.9% | 90.9% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.66 | 53.0 | 4.84e-01 | 84.8% | 93.3% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.66 | 56.0 | 5.10e-01 | 89.1% | 94.0% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.66 | 49.0 | 4.82e-01 | 78.3% | 79.8% |
| 2gomA00 | 1.10.10.1270 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sbi, C3 binding domain IV | 0.66 | 42.0 | 4.93e-01 | 80.4% | 96.7% |
| 1xl3C00 | 1.20.1280.80 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.66 | 58.0 | 5.93e-01 | 98.9% | 97.8% |
| 2a0uB01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.65 | 52.0 | 4.36e-01 | 87.0% | 55.0% |
| 2yvkA01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.65 | 52.0 | 4.46e-01 | 87.0% | 54.7% |
| 4abnA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 48.0 | 3.40e-01 | 78.3% | 89.6% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 53.0 | 5.02e-01 | 88.0% | 99.1% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 47.0 | 4.28e-01 | 76.1% | 78.3% |
| 2vixA03 | 1.20.1280.240 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.64 | 56.0 | 5.24e-01 | 95.7% | 83.2% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.63 | 47.0 | 4.38e-01 | 78.3% | 81.0% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.62 | 47.0 | 5.16e-01 | 92.4% | 100.0% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 49.0 | 4.76e-01 | 84.8% | 100.0% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 51.0 | 4.63e-01 | 88.0% | 87.7% |
| 4e6hA00 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 54.0 | 3.38e-01 | 100.0% | 21.7% |
| 4flbA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 50.0 | 4.47e-01 | 88.0% | 62.6% |
| 4dlqA02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 54.0 | 5.35e-01 | 100.0% | 91.6% |
| 5fhiA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 46.0 | 4.09e-01 | 81.5% | 76.3% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.60 | 50.0 | 4.70e-01 | 90.2% | 97.3% |
| 5c9eB01 | 1.20.1280.80 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.60 | 49.0 | 5.02e-01 | 88.0% | 96.6% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.59 | 48.0 | 4.48e-01 | 85.9% | 80.0% |
| 8j50A01 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.59 | 52.0 | 3.54e-01 | 96.7% | 36.3% |
| 7ar7E01 | 1.10.10.1590 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E | 0.58 | 37.0 | 4.45e-01 | 72.8% | 96.8% |
| 3h20A04 | 1.10.1240.50 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › | 0.57 | 46.0 | 4.71e-01 | 96.7% | 94.4% |
| 4rv1F00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.56 | 44.0 | 2.89e-01 | 84.8% | 27.7% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 42.0 | 4.03e-01 | 82.6% | 93.8% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.56 | 47.0 | 3.92e-01 | 89.1% | 61.3% |
| 2i2xB01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.55 | 46.0 | 4.56e-01 | 94.6% | 85.0% |
| 1h97A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 42.0 | 3.68e-01 | 83.7% | 78.9% |
| 7dvqK01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.55 | 44.0 | 3.66e-01 | 89.1% | 64.7% |
| 2ygwA01 | 1.20.140.90 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain | 0.54 | 44.0 | 3.76e-01 | 89.1% | 77.1% |
| 3aqbB00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 47.0 | 3.31e-01 | 98.9% | 72.3% |
| 1wvtA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.52 | 45.0 | 3.90e-01 | 97.8% | 89.9% |
| 2lt3A01 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.51 | 38.0 | 3.76e-01 | 84.8% | 75.0% |
ECOD (55)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3591850 | 4030.1.1.0 ↗ | alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz | 0.87 | 59.0 | 6.98e-01 | 79.3% | 98.5% |
| 5045348 | 604.34.1.0 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase | 0.84 | 58.0 | 6.04e-01 | 70.7% | 82.4% |
| 3530124 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.82 | 66.0 | 6.99e-01 | 91.3% | 97.5% |
| 3304958 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.80 | 54.0 | 3.61e-01 | 71.7% | 19.7% |
| 184670 | 6068.1.1.1 ↗ | alpha arrays › T4 Bacteriophage Helicase Uvsw.1 › T4 Bacteriophage Helicase Uvsw.1 › T4 Bacteriophage Helicase Uvsw.1 › UvsW-1 | 0.78 | 59.0 | 6.30e-01 | 78.3% | 92.4% |
| 3789100 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.78 | 65.0 | 4.01e-01 | 100.0% | 16.1% |
| 3451615 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.75 | 54.0 | 3.57e-01 | 75.0% | 62.0% |
| 3930367 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.73 | 40.0 | 4.37e-01 | 91.3% | 65.3% |
| 4189563 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.73 | 48.0 | 4.91e-01 | 71.7% | 69.7% |
| 3938534 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.73 | 53.0 | 3.63e-01 | 77.2% | 22.6% |
| 5054723 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.73 | 48.0 | 5.01e-01 | 71.7% | 73.8% |
| 3271711 | 109.6.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF_N | 0.71 | 56.0 | 4.89e-01 | 84.8% | 62.9% |
| 4932900 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.71 | 47.0 | 4.72e-01 | 71.7% | 66.7% |
| 3335074 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.71 | 52.0 | 4.58e-01 | 76.1% | 82.3% |
| 3988856 | 4146.1.1.1 ↗ | alpha bundles › YqgQ-like › YqgQ-like › YqgQ-like › YqgQ-like | 0.71 | 49.0 | 5.44e-01 | 71.7% | 100.0% |
| 4956583 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.71 | 47.0 | 4.67e-01 | 71.7% | 66.0% |
| 4942190 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.70 | 46.0 | 4.72e-01 | 70.7% | 69.3% |
| 5068709 | 633.12.1.0 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like | 0.70 | 46.0 | 4.71e-01 | 71.7% | 69.7% |
| 3591530 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.69 | 37.0 | 3.28e-01 | 94.6% | 36.2% |
| 3237959 | 109.4.1.661 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CNOT11 | 0.69 | 55.0 | 3.64e-01 | 93.5% | 20.8% |
| 5001354 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.68 | 45.0 | 4.59e-01 | 71.7% | 69.7% |
| 3218104 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.68 | 49.0 | 4.45e-01 | 76.1% | 74.4% |
| 3524176 | 109.4.1.884 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_UBP24_USP9X-Y | 0.67 | 54.0 | 3.12e-01 | 93.5% | 8.7% |
| 3408927 | 109.4.1.33 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT | 0.67 | 55.0 | 3.34e-01 | 89.1% | 13.8% |
| 4001252 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 59.0 | 4.02e-01 | 97.8% | 35.6% |
| 3183972 | 109.4.1.70 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID | 0.67 | 58.0 | 4.59e-01 | 98.9% | 52.0% |
| 3583222 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 50.0 | 3.86e-01 | 88.0% | 34.9% |
| 3996807 | 109.4.1.308 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps39_1 | 0.66 | 59.0 | 3.59e-01 | 100.0% | 17.4% |
| 3211763 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.64 | 44.0 | 3.76e-01 | 70.7% | 88.7% |
| 3580104 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 45.0 | 4.46e-01 | 72.8% | 100.0% |
| 5039441 | 633.21.1.47 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › SPW | 0.64 | 46.0 | 4.39e-01 | 76.1% | 80.9% |
| 167231 | 532.2.1.4 ↗ | alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains › MxiC_C | 0.64 | 56.0 | 5.42e-01 | 95.7% | 91.3% |
| 3955184 | 3831.1.1.1 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI | 0.63 | 31.0 | 3.25e-01 | 88.0% | 47.1% |
| 3873855 | 109.4.1.884 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_UBP24_USP9X-Y | 0.63 | 54.0 | 3.28e-01 | 97.8% | 20.0% |
| 4954354 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.63 | 50.0 | 3.45e-01 | 88.0% | 39.4% |
| 4400977 | 604.34.1.0 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase | 0.63 | 43.0 | 4.49e-01 | 70.7% | 84.7% |
| 3614983 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 52.0 | 2.98e-01 | 92.4% | 9.2% |
| 3900047 | 109.25.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN | 0.62 | 56.0 | 4.96e-01 | 100.0% | 84.4% |
| 3594397 | 109.54.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 | 0.62 | 52.0 | 4.56e-01 | 100.0% | 60.0% |
| 4061821 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.61 | 41.0 | 4.34e-01 | 79.3% | 78.8% |
| 3254229 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.61 | 47.0 | 5.21e-01 | 85.9% | 100.0% |
| 3681983 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 49.0 | 4.78e-01 | 87.0% | 88.0% |
| 2394140 | 1203.1.2.1 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 | 0.60 | 46.0 | 3.78e-01 | 81.5% | 72.8% |
| 4014788 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 41.0 | 4.02e-01 | 71.7% | 94.2% |
| 3693385 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.59 | 51.0 | 3.94e-01 | 95.7% | 71.4% |
| 3235909 | 189.1.1.2 ↗ | alpha bundles › GTPase activation domain, GAP › GTPase activation domain, GAP › GTPase activation domain, GAP › RhoGAP | 0.59 | 49.0 | 3.87e-01 | 93.5% | 80.5% |
| 3792888 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 47.0 | 4.06e-01 | 88.0% | 88.6% |
| 4435347 | 6035.1.1.2 ↗ | alpha bundles › Primase helical domain › Primase helical domain › Primase helical domain › RepB_primase_C | 0.57 | 44.0 | 4.32e-01 | 84.8% | 81.0% |
| 4462922 | 109.4.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm | 0.57 | 48.0 | 3.84e-01 | 95.7% | 66.2% |
| 3966922 | 102.1.3.28 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain › PF27805 | 0.57 | 41.0 | 3.70e-01 | 88.0% | 53.4% |
| 2889550 | 4995.1.1.0 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like | 0.56 | 42.0 | 4.42e-01 | 81.5% | 100.0% |
| None | — | 0.56 | 48.0 | 3.01e-01 | 98.9% | 16.8% | |
| 3715165 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 47.0 | 3.25e-01 | 100.0% | 43.8% |
| 3470313 | 197.1.1.0 ↗ | alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like | 0.53 | 41.0 | 4.00e-01 | 87.0% | 74.3% |
| 3833252 | 4106.1.1.0 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack | 0.52 | 44.0 | 3.76e-01 | 92.4% | 77.2% |
D4
medium
residues 312-368
Domain cluster:
representative
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3iylU02 | 1.10.287.1520 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.85 | 65.0 | 6.73e-01 | 87.7% | 88.7% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.82 | 59.0 | 4.57e-01 | 84.2% | 37.1% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.81 | 73.0 | 5.69e-01 | 100.0% | 82.1% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.80 | 72.0 | 5.78e-01 | 100.0% | 82.6% |
| 4hb9A01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.76 | 63.0 | 3.83e-01 | 93.0% | 85.6% |
| 4k08A00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.75 | 57.0 | 4.18e-01 | 86.0% | 31.9% |
| 2yw6B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.75 | 63.0 | 4.67e-01 | 96.5% | 70.7% |
| 3kd3A02 | 1.10.150.210 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Phosphoserine phosphatase; domain 2 | 0.73 | 47.0 | 4.64e-01 | 70.2% | 61.7% |
| 4cgyA02 | 1.10.460.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 2 › Topoisomerase I, domain 2 | 0.73 | 60.0 | 4.20e-01 | 98.2% | 27.9% |
| 6dv2G02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.72 | 63.0 | 4.35e-01 | 96.5% | 55.4% |
| 1yozA00 | 1.10.3200.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like | 0.71 | 62.0 | 4.94e-01 | 98.2% | 72.6% |
| 2nn4A00 | 1.10.287.760 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like | 0.70 | 55.0 | 5.36e-01 | 86.0% | 95.2% |
| 1t7lB01 | 3.20.20.210 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › | 0.69 | 55.0 | 3.33e-01 | 87.7% | 89.7% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.69 | 60.0 | 5.51e-01 | 98.2% | 92.0% |
| 3qnmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.68 | 51.0 | 4.31e-01 | 78.9% | 52.2% |
| 2y1eA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.68 | 48.0 | 4.21e-01 | 78.9% | 49.4% |
| 4cpgA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.68 | 48.0 | 4.52e-01 | 86.0% | 62.3% |
| 3fvvA02 | 1.20.1440.100 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › SG protein - dephosphorylation function | 0.67 | 49.0 | 4.53e-01 | 80.7% | 60.0% |
| 3zdmB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.67 | 48.0 | 5.04e-01 | 87.7% | 88.0% |
| 1osnC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.66 | 54.0 | 3.43e-01 | 94.7% | 18.2% |
| 1xdxA01 | 3.30.1140.40 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 | 0.66 | 44.0 | 3.70e-01 | 70.2% | 41.0% |
| 1grjA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.66 | 57.0 | 5.26e-01 | 98.2% | 82.4% |
| 1l5jA03 | 3.40.1060.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aconitase; Domain 2 › Aconitase, Domain 2 | 0.65 | 51.0 | 3.72e-01 | 91.2% | 40.5% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 55.0 | 5.03e-01 | 98.2% | 74.4% |
| 1mw9X02 | 1.10.460.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 2 › Topoisomerase I, domain 2 | 0.62 | 50.0 | 3.76e-01 | 94.7% | 35.6% |
| 7tj4A01 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 40.0 | 3.20e-01 | 71.9% | 30.8% |
| 2da3A01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.61 | 37.0 | 4.04e-01 | 82.5% | 74.5% |
| 1ailA00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.59 | 46.0 | 4.34e-01 | 87.7% | 70.0% |
| 3lupA01 | 3.40.50.10170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.58 | 43.0 | 3.20e-01 | 80.7% | 90.3% |
| 2go7A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.56 | 46.0 | 4.38e-01 | 93.0% | 100.0% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4203622 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.84 | 77.0 | 5.32e-01 | 100.0% | 91.4% |
| 3809254 | 509.1.1.1 ↗ | alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH | 0.82 | 51.0 | 4.89e-01 | 73.7% | 55.4% |
| 4056285 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.79 | 70.0 | 5.91e-01 | 100.0% | 61.1% |
| 3412555 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.77 | 64.0 | 5.18e-01 | 94.7% | 48.2% |
| 3486312 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.74 | 63.0 | 4.91e-01 | 98.2% | 44.5% |
| 4120236 | 192.29.1.236 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › AKAP95 | 0.74 | 64.0 | 5.97e-01 | 96.5% | 95.7% |
| 5003459 | 101.1.2.19 ↗ | alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac | 0.74 | 64.0 | 4.43e-01 | 96.5% | 29.7% |
| 3317228 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.74 | 62.0 | 5.45e-01 | 94.7% | 63.5% |
| 3386014 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.73 | 63.0 | 4.00e-01 | 98.2% | 19.3% |
| 4996292 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.72 | 60.0 | 5.00e-01 | 100.0% | 53.0% |
| 5055565 | 192.15.1.224 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › SHOCT | 0.72 | 61.0 | 4.76e-01 | 98.2% | 81.5% |
| 3967290 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.72 | 61.0 | 5.70e-01 | 98.2% | 77.1% |
| 4984709 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.70 | 60.0 | 5.45e-01 | 100.0% | 98.8% |
| 5083713 | 101.1.2.19 ↗ | alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac | 0.69 | 58.0 | 4.63e-01 | 96.5% | 45.8% |
| 1812412 | 1054.1.1.1 ↗ | alpha bundles › Arginine decarboxylase C-terminal helical extension › Arginine decarboxylase C-terminal helical extension › Arginine decarboxylase C-terminal helical extension › Arg_decarbox_C | 0.68 | 55.0 | 5.68e-01 | 87.7% | 92.5% |
| 1812419 | 1054.1.1.1 ↗ | alpha bundles › Arginine decarboxylase C-terminal helical extension › Arginine decarboxylase C-terminal helical extension › Arginine decarboxylase C-terminal helical extension › Arg_decarbox_C | 0.68 | 55.0 | 5.67e-01 | 87.7% | 92.5% |
| 3818544 | 109.4.1.1292 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3 | 0.64 | 42.0 | 2.84e-01 | 80.7% | 16.3% |
| 3930836 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 52.0 | 4.16e-01 | 98.2% | 45.8% |
D5
medium
residues 549-721
Domain cluster:
rep: MN061582.1__QFR59036.1__X__00051__D117-259
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3k2tA01 | 3.30.505.50 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain | 0.61 | 16.0 | 2.98e-01 | 70.5% | 76.1% |
| 4qqsB00 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.57 | 43.0 | 3.59e-01 | 78.0% | 90.7% |
| 1jnrB02 | 6.20.260.10 | Special › Other non-globular › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Adenylylsulphate reductase, beta subunit, C-terminal domain | 0.56 | 17.0 | 2.46e-01 | 82.7% | 50.6% |
| 4dm5A00 | 3.30.1450.10 | Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › | 0.55 | 21.0 | 2.86e-01 | 71.1% | 64.4% |
| 1qhwA00 | 3.60.21.10 | Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases | 0.50 | 43.0 | 3.60e-01 | 91.9% | 97.3% |
| 1gydB00 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.50 | 41.0 | 3.39e-01 | 86.7% | 78.7% |
| 4v1ag00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.50 | 27.0 | 2.86e-01 | 92.5% | 56.1% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3936442 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.69 | 24.0 | 3.14e-01 | 77.5% | 54.0% |
| 3080512 | 330.2.1.1 ↗ | a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › Ribosomal_S30AE | 0.58 | 28.0 | 3.58e-01 | 79.2% | 78.4% |
| 3561050 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.58 | 47.0 | 3.08e-01 | 85.5% | 87.8% |
| 3960850 | 244.2.1.0 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain | 0.55 | 21.0 | 3.46e-01 | 99.4% | 100.0% |
| 5061559 | 5.1.4.235 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_IFT140_1st | 0.55 | 42.0 | 3.39e-01 | 79.8% | 60.9% |
| 4410540 | 3321.1.1.1 ↗ | a+b two layers › Meander beta sheet domain in fatty acid synthase subunit beta › Meander beta sheet domain in fatty acid synthase subunit beta › Meander beta sheet domain in fatty acid synthase subunit beta › FAS_meander | 0.54 | 27.0 | 3.66e-01 | 75.1% | 95.3% |
| 4974630 | 220.1.1.76 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_2 | 0.53 | 23.0 | 2.86e-01 | 82.7% | 64.0% |
| 3707477 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.52 | 39.0 | 3.01e-01 | 78.0% | 78.3% |
| 2773986 | 2003.1.2.15 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 | 0.52 | 40.0 | 3.01e-01 | 81.5% | 95.1% |
| 4025955 | 5.1.4.271 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40, PF30361 | 0.51 | 43.0 | 3.25e-01 | 90.8% | 84.9% |
| 3548144 | 2485.1.1.69 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › DUF4174 | 0.51 | 30.0 | 3.23e-01 | 71.7% | 64.7% |
| 4010956 | 5.1.4.332 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PF29748 | 0.50 | 40.0 | 3.19e-01 | 85.0% | 64.8% |
D6
medium
residues 728-907
Domain cluster:
rep: OM362522.1__UPO38812.1__GHSM17_11__00011__D182-363
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1xjuA00 | 1.10.530.40 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.56 | 45.0 | 4.78e-01 | 86.7% | 98.7% |
| 2lm4A01 | 1.10.150.250 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Flavinator of succinate dehydrogenase | 0.54 | 29.0 | 3.79e-01 | 98.3% | 98.9% |