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YP_009666078.1

Arc-Vir

NC_043427__YP_009666078.1__FK997-gp33__00033

Identity

Accession:
NC_043427 ↗
Protein ID:
YP_009666078.1 ↗
Kingdom:
archaea

Quality

87.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 14-76
PDB
Pfam (5)
AccessionNameScoreE-valueQ covHMM cov
PF01710.23 best HTH_Tnp_IS630 31.0 3.20e-07 95.2% 43.7%
PF01527.27 HTH_Tnp_1 26.5 8.50e-06 95.2% 72.0%
PF13518.13 HTH_28 28.2 2.20e-06 58.7% 59.6%
PF13384.13 HTH_23 34.2 2.20e-08 57.1% 62.0%
PF02796.22 HTH_7 36.5 6.10e-09 55.6% 71.1%
CATH (49)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4gvpA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.76 56.0 3.91e-01 79.4% 26.7%
3oioA00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.76 68.0 5.61e-01 100.0% 91.1%
4fe7A03 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.76 63.0 5.35e-01 95.2% 94.5%
1p4wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 56.0 5.06e-01 81.0% 71.3%
3mklA00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.74 66.0 5.58e-01 100.0% 97.1%
5fo5A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 55.0 4.90e-01 79.4% 70.5%
1a9xA04 1.10.1030.10 Mainly Alpha › Orthogonal Bundle › Carbamoyl Phosphate Synthetase; Chain A, domain 4 › Carbamoyl-phosphate synthetase, large subunit oligomerisation domain 0.74 53.0 3.98e-01 76.2% 44.0%
3ulqB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 55.0 5.77e-01 82.5% 91.4%
2lvsA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.71 49.0 5.16e-01 79.4% 82.1%
1a04A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 55.0 5.08e-01 84.1% 67.5%
6jqsA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 53.0 5.20e-01 79.4% 88.1%
2esnA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 52.0 4.67e-01 79.4% 68.5%
4i2oA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 49.0 4.53e-01 73.0% 75.0%
5y9sC01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 52.0 4.77e-01 79.4% 74.4%
3p7nA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 54.0 5.21e-01 84.1% 77.8%
2ijlB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 52.0 4.32e-01 79.4% 56.0%
6uglB02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 51.0 5.36e-01 79.4% 87.9%
5f64A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 53.0 5.08e-01 84.1% 74.7%
2o3fA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 55.0 5.13e-01 90.5% 73.2%
4dyqA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.69 48.0 4.15e-01 74.6% 50.5%
6cc0A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 50.0 4.90e-01 77.8% 77.1%
1l3lA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 50.0 5.05e-01 77.8% 85.7%
6v7xB02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 53.0 5.53e-01 84.1% 96.4%
1b9mB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 49.0 4.26e-01 77.8% 55.6%
3tgnB02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.67 46.0 4.65e-01 71.4% 93.7%
5y2vC01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 49.0 4.49e-01 79.4% 72.9%
4ev0A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 45.0 4.28e-01 73.0% 72.7%
2dt5B01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 48.0 4.56e-01 77.8% 79.5%
5xsoA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 48.0 4.59e-01 82.5% 69.7%
3s5rB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 55.0 3.93e-01 100.0% 40.3%
3onqA03 1.10.10.2840 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain 0.63 49.0 4.00e-01 88.9% 48.9%
8h4pA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.63 55.0 3.52e-01 96.8% 31.8%
7watB02 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.62 53.0 3.42e-01 96.8% 33.6%
3ni7A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 54.0 3.96e-01 98.4% 42.0%
4xviA01 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.62 47.0 3.70e-01 85.7% 67.4%
1br2A03 1.20.120.720 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Myosin VI head, motor domain, U50 subdomain 0.61 50.0 4.33e-01 87.3% 85.3%
5z4zC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 53.0 4.71e-01 95.2% 97.7%
5d0yA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.61 48.0 3.72e-01 90.5% 82.6%
2ke4A00 6.10.140.470 Special › Helix non-globular › Helix Hairpins › 0.61 50.0 4.39e-01 98.4% 60.2%
3fxqB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 53.0 4.73e-01 98.4% 97.8%
4yifF00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 50.0 4.11e-01 100.0% 62.3%
3ecoB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 46.0 3.69e-01 84.1% 50.4%
3zh9B03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.60 52.0 4.10e-01 96.8% 47.6%
5trdA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 45.0 4.18e-01 85.7% 100.0%
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.59 46.0 3.61e-01 88.9% 80.6%
4x0qA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.56 45.0 3.54e-01 90.5% 80.6%
2uyyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.54 46.0 3.66e-01 92.1% 62.6%
1ailA00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.53 42.0 4.10e-01 90.5% 94.3%
1s7oB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 46.0 3.84e-01 95.2% 77.1%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4010677 101.1.1.58 alpha arrays › HTH › HTH › Three-helical HTH › HTH_18 0.84 73.0 6.15e-01 93.7% 64.0%
3282193 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.83 58.0 6.42e-01 73.0% 100.0%
4471924 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.82 58.0 6.21e-01 74.6% 94.5%
3956134 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.82 58.0 6.20e-01 74.6% 96.4%
3969568 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.82 58.0 6.19e-01 74.6% 94.5%
4131872 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.80 57.0 6.04e-01 74.6% 94.5%
3977556 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.78 56.0 5.96e-01 76.2% 98.2%
3289875 101.1.1.58 alpha arrays › HTH › HTH › Three-helical HTH › HTH_18 0.78 65.0 5.85e-01 93.7% 71.1%
3971154 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.78 58.0 5.62e-01 79.4% 80.0%
3964790 101.1.1.58 alpha arrays › HTH › HTH › Three-helical HTH › HTH_18 0.78 69.0 5.80e-01 98.4% 92.4%
3981688 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.78 61.0 6.12e-01 85.7% 87.7%
4590066 101.1.1.58 alpha arrays › HTH › HTH › Three-helical HTH › HTH_18 0.77 65.0 5.37e-01 93.7% 55.8%
None 0.77 69.0 5.89e-01 100.0% 100.0%
3289244 101.1.1.58 alpha arrays › HTH › HTH › Three-helical HTH › HTH_18 0.77 62.0 6.18e-01 88.9% 92.3%
3285795 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.77 55.0 5.82e-01 74.6% 96.4%
3973662 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.75 63.0 5.45e-01 93.7% 63.0%
3283959 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.75 62.0 5.59e-01 93.7% 72.2%
2761 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.75 56.0 5.06e-01 81.0% 71.3%
3981026 101.1.1.58 alpha arrays › HTH › HTH › Three-helical HTH › HTH_18 0.75 67.0 5.63e-01 100.0% 97.1%
5053441 101.1.1.371 alpha arrays › HTH › HTH › Three-helical HTH › UPF0175 0.75 49.0 5.08e-01 74.6% 71.7%
3288310 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.74 58.0 5.69e-01 87.3% 84.3%
4211867 101.1.1.58 alpha arrays › HTH › HTH › Three-helical HTH › HTH_18 0.74 66.0 5.48e-01 100.0% 93.6%
3953111 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.74 55.0 5.30e-01 79.4% 78.6%
4955851 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.73 54.0 3.80e-01 79.4% 30.0%
4492035 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.73 54.0 5.25e-01 79.4% 78.6%
4404485 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.73 53.0 5.47e-01 77.8% 86.7%
4987653 101.1.2.139 alpha arrays › HTH › HTH › winged helix domain › HTH_23 0.73 47.0 5.34e-01 77.8% 91.1%
4973199 101.1.1.60 alpha arrays › HTH › HTH › Three-helical HTH › HTH_23 0.73 57.0 5.80e-01 92.1% 88.3%
3942695 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.72 56.0 5.59e-01 84.1% 89.2%
3603167 101.1.1.17 alpha arrays › HTH › HTH › Three-helical HTH › HTH_7 0.72 56.0 5.60e-01 92.1% 81.5%
4976803 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.72 53.0 4.76e-01 79.4% 68.5%
4297073 101.1.2.1 alpha arrays › HTH › HTH › winged helix domain › HTH_1 0.72 54.0 4.74e-01 79.4% 68.9%
3619451 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.71 51.0 5.04e-01 74.6% 76.9%
4014219 4156.1.1.0 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like 0.71 54.0 3.84e-01 81.0% 41.1%
4993585 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.71 51.0 5.21e-01 81.0% 80.0%
3975610 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.70 54.0 5.25e-01 84.1% 77.1%
3941460 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.70 52.0 5.19e-01 79.4% 84.6%
3974013 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.70 54.0 5.51e-01 84.1% 86.7%
2440126 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.70 54.0 5.00e-01 84.1% 69.5%
4971448 101.1.11.0 alpha arrays › HTH › HTH › Ribbon-helix-helix 0.70 50.0 4.74e-01 76.2% 65.3%
5041148 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.69 51.0 4.95e-01 87.3% 71.4%
3290024 101.1.3.1 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.69 57.0 5.27e-01 92.1% 73.8%
3972270 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.69 54.0 5.24e-01 85.7% 78.6%
3280379 101.1.3.4 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 0.68 53.0 4.61e-01 85.7% 59.0%
3286796 101.1.3.4 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 0.68 51.0 4.44e-01 79.4% 55.8%
3962552 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.68 54.0 5.14e-01 88.9% 77.3%
5011873 4156.1.1.6 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Helicase_dom4_arc 0.66 52.0 3.84e-01 96.8% 32.7%
4974224 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.66 52.0 5.36e-01 98.4% 96.7%
4998383 101.1.2.1 alpha arrays › HTH › HTH › winged helix domain › HTH_1 0.65 48.0 4.25e-01 79.4% 77.9%
3991300 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.61 54.0 4.98e-01 100.0% 76.2%
4458965 101.1.1.63 alpha arrays › HTH › HTH › Three-helical HTH › HTH_28 0.58 53.0 4.88e-01 100.0% 91.3%
4048446 148.1.3.26 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_9 0.58 49.0 3.34e-01 98.4% 25.7%
3278243 101.1.4.10 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › DUF1870 0.55 45.0 3.61e-01 88.9% 50.0%
2970332 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.55 45.0 3.50e-01 93.7% 58.7%
4848450 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.54 44.0 3.51e-01 93.7% 60.4%
3198767 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.50 42.0 4.38e-01 95.2% 93.3%
D2 high residues 84-176
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1q5nA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.68 41.0 4.33e-01 91.4% 67.9%
2uy1A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 53.0 3.45e-01 90.3% 39.7%
6n2nA01 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.62 52.0 4.26e-01 93.5% 96.1%
2c42A03 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.61 51.0 3.94e-01 92.5% 90.1%
6ks6G01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.57 48.0 3.51e-01 93.5% 86.5%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 43.0 4.02e-01 87.1% 91.0%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 43.0 3.88e-01 87.1% 72.3%
3fblA00 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 42.0 4.40e-01 91.4% 97.6%
2hnlA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 37.0 3.61e-01 76.3% 91.8%
1xd4A03 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.52 42.0 3.28e-01 92.5% 53.5%
4uskA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.51 38.0 3.28e-01 91.4% 48.1%
2mx8A01 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.51 42.0 3.99e-01 93.5% 93.8%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.50 35.0 3.51e-01 72.0% 98.0%
2zs0A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.50 43.0 3.84e-01 97.8% 82.1%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4984686 186.1.1.0 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N 0.85 74.0 7.14e-01 93.5% 88.6%
4998253 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.79 41.0 4.97e-01 87.1% 78.3%
3236092 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.61 48.0 5.11e-01 86.0% 98.8%
3351905 3745.1.1.1 alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex 0.61 46.0 3.60e-01 81.7% 83.3%
3528431 633.21.1.24 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › PF25970 0.61 49.0 4.57e-01 86.0% 96.5%
3943035 639.2.1.0 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.57 38.0 4.35e-01 72.0% 98.5%
4967993 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.57 44.0 4.63e-01 89.2% 92.8%
4946659 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.57 42.0 4.01e-01 79.6% 100.0%
3455585 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.56 46.0 4.54e-01 95.7% 86.0%
3973500 601.1.2.144 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HBM 0.52 41.0 3.85e-01 86.0% 97.4%
4965784 3455.1.1.17 alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors › DUF7853 0.52 41.0 4.27e-01 86.0% 100.0%
4928310 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.51 41.0 4.15e-01 92.5% 90.3%
3488467 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.50 41.0 3.92e-01 94.6% 86.1%
D3 high residues 186-229_285-397
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5jk0B01 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.74 56.0 5.46e-01 78.3% 100.0%
3nkhA00 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.74 62.0 5.47e-01 87.9% 98.2%
1aihA00 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.72 60.0 5.83e-01 86.0% 92.4%
1f44A01 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.71 57.0 5.29e-01 83.4% 100.0%
1iurA01 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.66 27.0 4.09e-01 96.8% 92.1%
2cazE00 1.20.1440.200 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Vps28 N-terminal domain 0.54 29.0 3.52e-01 99.4% 79.2%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4004483 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.76 63.0 5.83e-01 86.0% 96.3%
3498502 627.1.1.2 alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › DUF5601 0.60 29.0 3.66e-01 98.7% 74.7%
4962406 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.60 33.0 3.09e-01 100.0% 41.4%
3743047 604.5.1.28 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TBCC_N 0.55 29.0 3.77e-01 99.4% 91.8%
3714093 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 26.0 3.15e-01 100.0% 68.0%
3940870 3069.1.1.1 alpha arrays › BART › BART › BART › ARL2_Bind_BART 0.52 31.0 3.34e-01 92.4% 66.7%
3233936 627.1.1.2 alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › DUF5601 0.52 31.0 3.96e-01 73.2% 100.0%
5008649 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.50 33.0 3.07e-01 100.0% 51.5%
5043389 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.50 33.0 3.06e-01 100.0% 51.5%
D4 medium residues 230-284
PDB
Domain cluster: representative
CATH (82)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3bwlB00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.74 52.0 4.03e-01 74.5% 34.1%
2k75A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.73 53.0 4.22e-01 100.0% 40.8%
4ywzB00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.71 52.0 3.84e-01 80.0% 82.2%
3volA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.70 50.0 3.71e-01 76.4% 30.4%
1pfsA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.69 51.0 4.65e-01 100.0% 57.7%
1f98A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.69 50.0 3.86e-01 78.2% 94.4%
6zj8D01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.69 48.0 3.84e-01 74.5% 37.7%
4pkcC00 6.20.90.20 Special › Other non-globular › SH3 type barrels. › Benzylsuccinate synthase gamma subunit 0.69 48.0 5.35e-01 78.2% 100.0%
2yh6D00 3.30.530.50 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › 0.68 47.0 3.82e-01 74.5% 40.0%
1ul7A00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.68 48.0 3.95e-01 76.4% 41.2%
2xzhA00 2.130.10.110 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Clathrin heavy-chain terminal domain 0.68 51.0 3.08e-01 80.0% 15.9%
3b33A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.67 46.0 3.81e-01 74.5% 38.5%
3zpeA00 2.60.90.50 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › 0.66 47.0 3.55e-01 78.2% 30.4%
3tfzB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.66 45.0 3.22e-01 76.4% 23.6%
1dq3A03 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.65 56.0 4.87e-01 100.0% 94.3%
2be3B01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.65 48.0 3.59e-01 80.0% 34.8%
1dleB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.64 44.0 3.34e-01 72.7% 47.9%
1qlmA02 3.30.1030.10 Alpha Beta › 2-Layer Sandwich › Methenyltetrahydromethanopterin Cyclohydrolase; Chain A, domain 2 › Methenyltetrahydromethanopterin Cyclohydrolase; Chain A, domain 2 0.64 47.0 3.31e-01 81.8% 42.9%
3obqA00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.64 49.0 3.70e-01 83.6% 36.9%
4d10F01 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.64 49.0 3.47e-01 85.5% 86.6%
4i86A00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.64 43.0 3.55e-01 80.0% 38.2%
4p2iA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.64 54.0 4.34e-01 100.0% 80.3%
3c19A02 3.10.20.300 Alpha Beta › Roll › Ubiquitin-like (UB roll) › mk0293 like domain 0.64 43.0 3.84e-01 72.7% 50.0%
3llcA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.63 45.0 2.92e-01 76.4% 28.4%
4fchA01 2.60.40.3620 Mainly Beta › Sandwich › Immunoglobulin-like › 0.63 46.0 3.79e-01 80.0% 98.2%
4ec6A00 3.10.450.540 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.63 49.0 3.92e-01 85.5% 45.9%
1bf5A04 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.63 50.0 4.07e-01 92.7% 71.7%
7prrB01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.61 51.0 3.66e-01 94.5% 58.0%
1jeyB02 2.40.290.10 Mainly Beta › Beta Barrel › Ku70; Chain: A; Domain 2 › 0.61 46.0 3.17e-01 81.8% 40.8%
3lidA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.61 48.0 3.70e-01 89.1% 41.0%
2i9yA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.61 44.0 3.24e-01 78.2% 29.9%
7vljA01 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.61 44.0 3.78e-01 78.2% 97.8%
2kvtA00 3.30.730.30 Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › YaiA protein 0.61 46.0 4.29e-01 94.5% 66.2%
8aasC01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 39.0 3.22e-01 100.0% 35.3%
4efjA01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.60 48.0 3.74e-01 96.4% 55.0%
2dchX02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.60 51.0 4.17e-01 100.0% 70.3%
2jysA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.60 42.0 3.66e-01 76.4% 70.3%
2zbbA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.60 40.0 3.59e-01 72.7% 46.9%
2k54A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 43.0 3.39e-01 78.2% 38.2%
4l22A01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.59 44.0 2.67e-01 83.6% 39.3%
7oufB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.59 53.0 3.84e-01 100.0% 45.0%
3ub1D02 3.10.450.540 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 50.0 4.00e-01 96.4% 67.5%
4c89C00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 51.0 3.14e-01 96.4% 16.8%
2gk6A02 2.40.30.230 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.59 52.0 4.58e-01 100.0% 89.2%
4ebrA00 3.30.1460.50 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.59 49.0 3.64e-01 96.4% 69.4%
8b4hA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.59 49.0 3.61e-01 100.0% 60.5%
4k08A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.59 43.0 3.21e-01 80.0% 83.3%
4lrzE02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.58 40.0 3.46e-01 74.5% 42.6%
2pgeA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.58 48.0 3.77e-01 96.4% 47.2%
1sr4B00 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.58 46.0 3.01e-01 96.4% 19.0%
3upuA03 2.30.30.780 Mainly Beta › Roll › SH3 type barrels. › 0.58 49.0 3.77e-01 98.2% 93.9%
2d9wA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.58 47.0 3.92e-01 100.0% 49.1%
1tuhA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 40.0 3.19e-01 78.2% 35.9%
1tzzB01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.57 45.0 3.77e-01 100.0% 52.1%
6kmoB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 47.0 2.94e-01 94.5% 16.8%
6gp1A00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.57 39.0 3.76e-01 76.4% 61.5%
1jhnA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.57 47.0 3.14e-01 94.5% 45.3%
7rd0A02 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.56 42.0 2.67e-01 83.6% 72.4%
2k4vA00 3.30.160.370 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Domain of unknown function DUF5064 0.56 47.0 3.66e-01 94.5% 72.0%
1fmbA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.56 40.0 3.38e-01 78.2% 67.3%
5ig0A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 46.0 3.48e-01 89.1% 78.6%
2cy5A00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 45.0 3.61e-01 100.0% 52.7%
2lpuA00 3.30.1460.50 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.56 46.0 3.48e-01 96.4% 68.9%
3bxpB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 45.0 2.96e-01 92.7% 22.5%
1s3rA02 3.30.1040.20 Alpha Beta › 2-Layer Sandwich › Carboxypeptidase Inhibitor; Chain A › 0.56 41.0 4.17e-01 76.4% 84.9%
6f1uK02 3.90.1150.210 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit 0.55 44.0 3.34e-01 90.9% 68.3%
6m9yA00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.55 37.0 3.71e-01 74.5% 68.4%
2qkpD00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.55 41.0 3.18e-01 83.6% 35.8%
2i9wA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 45.0 3.21e-01 96.4% 41.5%
3akoC00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.54 37.0 2.80e-01 76.4% 26.8%
1whqA01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.54 41.0 3.85e-01 87.3% 73.2%
2g2sA00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.54 37.0 3.56e-01 76.4% 62.5%
3htyA00 2.40.128.280 Mainly Beta › Beta Barrel › Lipocalin › 0.53 44.0 3.79e-01 98.2% 60.6%
2eenA00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.53 42.0 3.02e-01 90.9% 31.1%
1tkjA00 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.53 37.0 2.42e-01 76.4% 38.3%
1jt8A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 43.0 3.59e-01 96.4% 75.5%
1cjxB02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.52 37.0 2.63e-01 80.0% 34.7%
3gkmA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.52 40.0 3.07e-01 94.5% 75.2%
4rt0A00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.52 37.0 3.09e-01 85.5% 40.4%
1nf3C00 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.51 40.0 3.34e-01 100.0% 79.7%
4ffeX00 3.30.500.10 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › MHC class I-like antigen recognition-like 0.51 40.0 3.05e-01 94.5% 88.7%
4jgpA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.50 34.0 2.97e-01 74.5% 41.4%
ECOD (94)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4959104 223.1.1.25 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_9 0.80 56.0 4.36e-01 74.5% 36.5%
4958220 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.77 54.0 4.10e-01 74.5% 33.8%
4226251 375.1.1.252 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › PF27302 0.75 52.0 5.07e-01 81.8% 66.7%
4960078 223.1.1.25 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_9 0.75 53.0 3.37e-01 74.5% 16.9%
3942790 4312.1.1.0 a+b two layers › RelE-like › RelE-like › RelE-like 0.75 52.0 4.90e-01 72.7% 61.5%
4930499 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.74 52.0 3.38e-01 74.5% 18.3%
3651210 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.73 52.0 5.08e-01 83.6% 68.3%
5048403 223.1.1.25 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_9 0.73 51.0 4.22e-01 74.5% 43.0%
4405445 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.73 54.0 5.00e-01 83.6% 62.9%
3517350 5.1.5.4 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DPPIV_N 0.72 55.0 3.38e-01 83.6% 15.1%
3577516 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.72 52.0 3.37e-01 76.4% 18.4%
3585516 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.72 50.0 4.51e-01 74.5% 56.4%
3642588 11.1.4.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.71 48.0 3.83e-01 72.7% 36.2%
4950605 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.71 50.0 3.86e-01 74.5% 34.4%
5034773 223.1.1.25 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_9 0.71 53.0 4.20e-01 80.0% 40.0%
3218749 295.1.1.4 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › COMM_domain 0.71 52.0 5.09e-01 78.2% 71.7%
4353676 223.1.1.41 a+b three layers › Profilin-like › sensor domains › sensor domains › HisK_sensor 0.70 52.0 3.94e-01 80.0% 85.9%
4980660 223.1.1.2 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS 0.70 52.0 4.15e-01 80.0% 40.9%
5044346 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.70 50.0 4.02e-01 76.4% 38.2%
4929236 3604.1.1.1 a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Ni_insertion 0.70 51.0 4.66e-01 80.0% 60.0%
4952182 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.70 52.0 4.14e-01 80.0% 40.0%
3212189 214.1.1.0 a+b two layers › SH2 › SH2 › SH2 0.70 60.0 4.77e-01 98.2% 56.5%
4999855 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.70 49.0 3.90e-01 74.5% 38.2%
4963337 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.69 50.0 3.80e-01 76.4% 34.6%
5050898 3604.1.1.1 a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Ni_insertion 0.69 48.0 4.41e-01 72.7% 60.0%
4935912 3604.1.1.1 a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Ni_insertion 0.69 51.0 4.71e-01 83.6% 61.4%
4959068 223.1.1.2 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS 0.69 49.0 3.05e-01 76.4% 14.0%
4043495 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.69 47.0 3.30e-01 74.5% 23.6%
3253359 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.69 56.0 3.47e-01 92.7% 32.1%
3637283 5.1.4.441 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Clathrin-link 0.68 52.0 3.13e-01 81.8% 15.4%
5031967 1.1.1.0 beta barrels › cradle loop barrel › RIFT-related › acid protease 0.68 50.0 4.01e-01 78.2% 40.9%
4951932 223.1.1.3 a+b three layers › Profilin-like › sensor domains › sensor domains › GAF 0.68 48.0 2.98e-01 74.5% 14.7%
3985160 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.67 50.0 4.02e-01 81.8% 40.0%
5002461 223.1.1.25 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_9 0.67 47.0 3.64e-01 72.7% 35.0%
3971053 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.66 49.0 3.95e-01 80.0% 41.8%
4982570 3604.1.1.1 a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Ni_insertion 0.66 47.0 4.40e-01 80.0% 60.0%
3901529 11.1.1.640 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ZP-N 0.66 50.0 4.16e-01 81.8% 68.4%
4346250 4099.1.1.0 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.66 50.0 3.68e-01 81.8% 32.1%
5047293 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.66 46.0 3.54e-01 74.5% 31.5%
5031616 4.26.1.0 beta barrels › SH3 › Chromatin protein Cren7 › Chromatin protein Cren7 0.66 47.0 4.78e-01 80.0% 78.2%
3612689 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.66 58.0 4.62e-01 100.0% 57.3%
5051876 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.66 46.0 3.60e-01 74.5% 34.4%
4045121 243.3.1.3 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.65 49.0 4.45e-01 85.5% 60.0%
4930368 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.65 45.0 3.69e-01 74.5% 37.3%
3954468 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.65 48.0 3.36e-01 80.0% 65.3%
3289119 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 44.0 2.63e-01 70.9% 10.1%
3456692 386.1.1.4 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED 0.65 47.0 4.68e-01 89.1% 72.9%
4984061 2484.1.1.59 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.64 55.0 3.44e-01 98.2% 78.0%
3676628 4.1.1.162 beta barrels › SH3 › SH3 › SH3 › DUF502 0.64 48.0 3.88e-01 98.2% 40.0%
3834362 3832.1.1.2 alpha bundles › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › PF25968 0.63 55.0 3.19e-01 100.0% 86.2%
4983267 2004.1.1.94 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATP_bind_1 0.63 48.0 3.43e-01 85.5% 28.6%
3270992 216.1.1.3 a+b two layers › UBC-like › UBC-like › UBC-like › UEV 0.63 46.0 3.55e-01 81.8% 35.7%
3832543 7516.1.1.41 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glucan_synthase 0.63 55.0 3.01e-01 100.0% 20.0%
5023444 1.1.1.5 beta barrels › cradle loop barrel › RIFT-related › acid protease › Zn_protease 0.63 45.0 3.69e-01 78.2% 68.2%
3645842 4.1.1.162 beta barrels › SH3 › SH3 › SH3 › DUF502 0.62 47.0 4.30e-01 98.2% 60.0%
3588750 243.3.1.3 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.62 46.0 4.29e-01 85.5% 62.7%
3863194 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.61 52.0 4.06e-01 100.0% 70.8%
5055900 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.61 43.0 3.25e-01 74.5% 31.4%
4086554 11.10.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like › Sina_TRAF 0.61 50.0 3.87e-01 96.4% 86.7%
5013672 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.61 51.0 4.92e-01 100.0% 87.7%
4971399 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.61 52.0 4.23e-01 100.0% 89.1%
3345737 5.1.3.65 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › DUF295 0.60 50.0 3.14e-01 92.7% 39.4%
3188394 4.8.1.22 beta barrels › SH3 › Chromo domain-like › Chromo domain-like › DUF7025 0.60 50.0 4.05e-01 98.2% 61.7%
4988723 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.60 44.0 3.54e-01 80.0% 39.1%
1159602 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.60 51.0 4.16e-01 100.0% 69.6%
3710433 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.60 50.0 4.08e-01 98.2% 76.4%
3824181 375.1.1.21 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-ZPR1 0.60 44.0 4.37e-01 81.8% 81.7%
5055280 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.59 41.0 3.11e-01 74.5% 33.1%
4935307 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.59 40.0 3.73e-01 76.4% 52.5%
3581254 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.58 42.0 4.28e-01 85.5% 80.0%
4018089 4099.1.1.0 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.58 48.0 3.81e-01 96.4% 71.7%
2490256 271.1.1.1 beta barrels › GFP-like › GFP-like › GFP-like › GFP 0.57 39.0 3.75e-01 76.4% 60.6%
4137219 2.1.1.6 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SSB 0.57 48.0 4.02e-01 100.0% 54.0%
2494924 295.1.1.4 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › COMM_domain 0.56 46.0 4.25e-01 100.0% 75.6%
5018717 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.56 39.0 3.96e-01 78.2% 74.5%
3771406 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.56 45.0 3.65e-01 100.0% 43.2%
3819309 330.1.1.5 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › DND1_DSRM 0.56 46.0 4.04e-01 92.7% 75.3%
3402087 868.1.1.0 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related 0.56 45.0 3.32e-01 96.4% 32.4%
4511768 5.1.3.117 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1+Kelch_KLHDC2_KLHL20_DRC7 0.55 46.0 2.94e-01 100.0% 92.6%
3258452 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.55 45.0 3.58e-01 92.7% 50.0%
3833240 283.2.1.0 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like 0.55 37.0 3.17e-01 70.9% 40.9%
5055744 5.1.3.40 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Arylsulfotran_2 0.55 47.0 2.88e-01 96.4% 68.7%
4797813 271.1.1.1 beta barrels › GFP-like › GFP-like › GFP-like › GFP 0.55 37.0 3.71e-01 74.5% 68.4%
4021885 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.54 37.0 2.53e-01 74.5% 26.1%
4191459 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.54 47.0 3.70e-01 100.0% 51.7%
4771028 271.1.1.1 beta barrels › GFP-like › GFP-like › GFP-like › GFP 0.54 36.0 3.57e-01 76.4% 63.5%
3179468 330.1.1.18 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › DSRM_DHX29 0.53 43.0 3.26e-01 96.4% 68.8%
3619212 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.53 37.0 2.41e-01 78.2% 18.7%
4106730 264.2.1.1 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac 0.53 45.0 3.47e-01 100.0% 52.6%
None 0.53 36.0 2.98e-01 76.4% 36.0%
3301984 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.52 37.0 3.76e-01 76.4% 83.6%
3692621 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.52 45.0 3.49e-01 100.0% 49.2%
3391411 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.51 34.0 3.80e-01 81.8% 97.5%
865437 241.1.1.2 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › Autophagy_act_C 0.50 42.0 3.11e-01 94.5% 66.9%