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NC_047834.1__YP_009790912.1__HOR85_gp38__00038
Bact-VirNC_047834.1__YP_009790912.1__HOR85_gp38__00038
Identity
- Accession:
- NC_047834 ↗
- Kingdom:
- phage
Quality
78.2
mean pLDDT
Taxonomy
Heunggongvirae›
Uroviricota›
Caudoviricetes›
Autographivirales›
Foturvirus›
Alteromonas_phage_vB_AspP-H4/4
TaxID: 2928692
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 107-196
Domain cluster:
representative
CATH (72)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.76 | 62.0 | 3.96e-01 | 90.0% | 19.3% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.76 | 59.0 | 5.50e-01 | 83.3% | 71.8% |
| 1txuA01 | 1.10.246.120 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.73 | 59.0 | 5.83e-01 | 86.7% | 87.2% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 53.0 | 5.12e-01 | 81.1% | 67.6% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.72 | 61.0 | 5.74e-01 | 92.2% | 100.0% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.71 | 48.0 | 4.96e-01 | 72.2% | 72.4% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.70 | 48.0 | 5.07e-01 | 70.0% | 87.2% |
| 4zvaA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.69 | 53.0 | 4.54e-01 | 83.3% | 89.9% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.68 | 61.0 | 5.35e-01 | 100.0% | 84.4% |
| 4uiqB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.68 | 52.0 | 4.44e-01 | 83.3% | 88.9% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 47.0 | 3.40e-01 | 72.2% | 27.3% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 60.0 | 5.67e-01 | 98.9% | 100.0% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.67 | 40.0 | 4.68e-01 | 72.2% | 84.4% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.67 | 53.0 | 5.64e-01 | 88.9% | 98.7% |
| 5m9dA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.67 | 47.0 | 4.08e-01 | 84.4% | 47.8% |
| 2a0uB01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.67 | 52.0 | 4.32e-01 | 84.4% | 48.1% |
| 4xxiA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.66 | 51.0 | 4.34e-01 | 82.2% | 81.0% |
| 2c0kB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.66 | 52.0 | 4.40e-01 | 84.4% | 97.3% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.66 | 56.0 | 4.26e-01 | 93.3% | 47.2% |
| 3tl4X02 | 1.10.10.2420 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.65 | 48.0 | 5.20e-01 | 86.7% | 95.8% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 58.0 | 4.70e-01 | 98.9% | 79.2% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.65 | 43.0 | 4.75e-01 | 71.1% | 88.2% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.65 | 44.0 | 3.91e-01 | 70.0% | 82.7% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.65 | 50.0 | 5.40e-01 | 90.0% | 97.4% |
| 4mo7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 54.0 | 4.72e-01 | 93.3% | 66.9% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 46.0 | 3.44e-01 | 74.4% | 34.0% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 57.0 | 5.16e-01 | 98.9% | 96.7% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.64 | 51.0 | 4.93e-01 | 93.3% | 77.8% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 45.0 | 3.34e-01 | 74.4% | 29.2% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.64 | 43.0 | 4.08e-01 | 72.2% | 58.3% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.63 | 44.0 | 4.31e-01 | 72.2% | 70.7% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.63 | 56.0 | 4.15e-01 | 100.0% | 89.3% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 56.0 | 4.88e-01 | 98.9% | 83.1% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 45.0 | 3.40e-01 | 74.4% | 44.3% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.63 | 41.0 | 4.33e-01 | 73.3% | 74.1% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.63 | 53.0 | 5.37e-01 | 93.3% | 97.7% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 54.0 | 5.25e-01 | 97.8% | 99.0% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 44.0 | 4.32e-01 | 73.3% | 91.7% |
| 2vs0A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.62 | 43.0 | 4.52e-01 | 73.3% | 79.3% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.62 | 56.0 | 4.59e-01 | 100.0% | 81.0% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.62 | 50.0 | 5.08e-01 | 90.0% | 97.8% |
| 4abnA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 55.0 | 3.90e-01 | 100.0% | 93.9% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.62 | 54.0 | 5.19e-01 | 100.0% | 98.1% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.62 | 42.0 | 4.31e-01 | 70.0% | 78.8% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 54.0 | 4.29e-01 | 98.9% | 66.1% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 43.0 | 4.50e-01 | 74.4% | 80.2% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.61 | 39.0 | 4.27e-01 | 72.2% | 81.7% |
| 6i3mE01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.61 | 50.0 | 4.38e-01 | 91.1% | 75.9% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.60 | 52.0 | 3.57e-01 | 96.7% | 89.2% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.59 | 44.0 | 4.09e-01 | 78.9% | 86.0% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 44.0 | 4.75e-01 | 81.1% | 97.3% |
| 2ke4A00 | 6.10.140.470 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 42.0 | 4.07e-01 | 73.3% | 68.4% |
| 1j77A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.58 | 47.0 | 3.72e-01 | 90.0% | 62.8% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.58 | 46.0 | 4.00e-01 | 86.7% | 81.9% |
| 2yqdA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.58 | 42.0 | 3.82e-01 | 75.6% | 69.2% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.57 | 41.0 | 3.71e-01 | 74.4% | 63.7% |
| 7zdtD01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.57 | 48.0 | 3.35e-01 | 95.6% | 85.0% |
| 4qndA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.57 | 48.0 | 4.70e-01 | 92.2% | 86.6% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.57 | 41.0 | 3.28e-01 | 84.4% | 37.1% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 41.0 | 3.52e-01 | 76.7% | 55.9% |
| 1pw4A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.56 | 47.0 | 3.63e-01 | 93.3% | 80.2% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.56 | 46.0 | 3.99e-01 | 92.2% | 64.6% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 47.0 | 4.72e-01 | 94.4% | 93.4% |
| 1hciA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 48.0 | 4.38e-01 | 98.9% | 92.9% |
| 5x9vA01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.56 | 46.0 | 3.45e-01 | 93.3% | 46.5% |
| 4i4cB00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.55 | 45.0 | 2.98e-01 | 91.1% | 37.2% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 47.0 | 4.67e-01 | 94.4% | 97.8% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.55 | 38.0 | 3.97e-01 | 72.2% | 97.5% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.55 | 39.0 | 4.09e-01 | 84.4% | 81.9% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 35.0 | 3.85e-01 | 73.3% | 83.8% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.53 | 43.0 | 3.99e-01 | 92.2% | 77.1% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.52 | 42.0 | 4.03e-01 | 85.6% | 86.1% |
ECOD (53)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3822 | 604.4.1.1 ↗ | alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP › AHSP | 0.86 | 74.0 | 7.46e-01 | 91.1% | 100.0% |
| 3686422 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.86 | 70.0 | 6.60e-01 | 91.1% | 73.3% |
| 4107263 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.78 | 65.0 | 5.43e-01 | 90.0% | 58.7% |
| 4646569 | 4994.1.1.1 ↗ | alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 | 0.75 | 67.0 | 6.59e-01 | 98.9% | 100.0% |
| 3722363 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.72 | 64.0 | 5.28e-01 | 97.8% | 79.4% |
| 3706056 | 604.22.1.0 ↗ | alpha bundles › Spectrin repeat-like › tubulin binding cofactor C N-terminal domain › tubulin binding cofactor C N-terminal domain | 0.72 | 62.0 | 6.37e-01 | 97.8% | 98.8% |
| 3965542 | 601.1.1.88 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › 6TM_PilS | 0.72 | 62.0 | 4.85e-01 | 95.6% | 76.8% |
| 4438700 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.71 | 58.0 | 5.99e-01 | 90.0% | 100.0% |
| 3789554 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.71 | 58.0 | 5.83e-01 | 92.2% | 87.8% |
| 3929572 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.70 | 59.0 | 6.09e-01 | 90.0% | 100.0% |
| 4290271 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.69 | 58.0 | 5.88e-01 | 98.9% | 90.0% |
| 4790111 | 6110.1.1.1 ↗ | alpha superhelices › Linker domain of cytoplasmic dynein heavy chain › Linker domain of cytoplasmic dynein heavy chain › Linker domain of cytoplasmic dynein heavy chain › DHC_N2 | 0.69 | 59.0 | 4.25e-01 | 93.3% | 59.8% |
| 3832320 | 5050.1.1.26 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UVB_sens_prot | 0.67 | 57.0 | 3.89e-01 | 93.3% | 96.0% |
| 3473769 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.67 | 48.0 | 3.40e-01 | 73.3% | 38.0% |
| 3235045 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.66 | 54.0 | 4.46e-01 | 88.9% | 94.4% |
| 3719058 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.66 | 55.0 | 5.64e-01 | 94.4% | 96.5% |
| 3656716 | 3755.3.1.498 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF31016 | 0.65 | 45.0 | 3.83e-01 | 71.1% | 65.5% |
| 3494742 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.65 | 46.0 | 3.86e-01 | 74.4% | 55.5% |
| 3409714 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.65 | 59.0 | 5.70e-01 | 100.0% | 96.0% |
| 3592663 | 604.22.1.0 ↗ | alpha bundles › Spectrin repeat-like › tubulin binding cofactor C N-terminal domain › tubulin binding cofactor C N-terminal domain | 0.64 | 53.0 | 5.19e-01 | 94.4% | 81.0% |
| 4203309 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.64 | 42.0 | 2.70e-01 | 73.3% | 13.8% |
| 3950977 | 5058.1.1.9 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Colicin_V | 0.64 | 49.0 | 4.12e-01 | 82.2% | 64.5% |
| 5078457 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.64 | 54.0 | 4.19e-01 | 94.4% | 48.3% |
| 4616546 | 6155.1.1.4 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC | 0.63 | 57.0 | 5.42e-01 | 100.0% | 85.7% |
| 4630202 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.63 | 43.0 | 4.33e-01 | 70.0% | 74.2% |
| 3744146 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.63 | 50.0 | 5.07e-01 | 88.9% | 100.0% |
| 3744084 | 563.1.1.1 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP | 0.63 | 45.0 | 3.57e-01 | 81.1% | 38.3% |
| 3839022 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.63 | 52.0 | 3.95e-01 | 90.0% | 69.8% |
| 4949471 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.62 | 46.0 | 3.80e-01 | 80.0% | 86.3% |
| 4311347 | 604.24.1.0 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in putative transcriptional regulator Jann_0659-related proteins › Helical bundle domain in putative transcriptional regulator Jann_0659-related proteins | 0.62 | 49.0 | 5.17e-01 | 93.3% | 97.5% |
| 4883675 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.62 | 41.0 | 4.44e-01 | 71.1% | 84.5% |
| 2799599 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.62 | 43.0 | 4.39e-01 | 73.3% | 75.6% |
| 3560590 | 3755.3.1.142 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › FAM186A-B_C | 0.62 | 43.0 | 3.65e-01 | 72.2% | 52.7% |
| 3584894 | 605.1.1.238 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › CNNM | 0.60 | 42.0 | 4.22e-01 | 72.2% | 93.3% |
| 4109908 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.59 | 41.0 | 4.24e-01 | 73.3% | 76.5% |
| 3396684 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.59 | 44.0 | 3.58e-01 | 80.0% | 82.9% |
| 3327722 | 5050.1.1.26 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UVB_sens_prot | 0.59 | 51.0 | 3.64e-01 | 100.0% | 65.1% |
| 3772767 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.59 | 41.0 | 3.68e-01 | 72.2% | 81.6% |
| 3557114 | 604.1.1.66 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL | 0.58 | 52.0 | 4.86e-01 | 98.9% | 98.2% |
| 3676218 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.58 | 49.0 | 3.92e-01 | 94.4% | 63.2% |
| 4024388 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.58 | 50.0 | 3.78e-01 | 96.7% | 41.8% |
| 3431415 | 6155.1.1.6 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921 | 0.58 | 46.0 | 4.73e-01 | 87.8% | 91.8% |
| 3420431 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.58 | 39.0 | 4.06e-01 | 74.4% | 74.1% |
| 3333417 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.57 | 38.0 | 3.88e-01 | 70.0% | 72.2% |
| 3214392 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.56 | 47.0 | 3.94e-01 | 95.6% | 79.4% |
| 4034406 | 632.15.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › CompInhib_SCIN | 0.56 | 39.0 | 4.01e-01 | 76.7% | 76.5% |
| 4129856 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.55 | 39.0 | 4.01e-01 | 76.7% | 77.6% |
| 4034431 | 632.15.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › CompInhib_SCIN | 0.55 | 39.0 | 4.01e-01 | 76.7% | 77.4% |
| 3407072 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.55 | 44.0 | 4.68e-01 | 92.2% | 100.0% |
| 5048247 | 632.1.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid | 0.52 | 39.0 | 3.83e-01 | 80.0% | 79.0% |
| 3991595 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.52 | 37.0 | 3.65e-01 | 74.4% | 72.6% |
| 3891868 | 5086.1.1.21 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › CARMIL_C | 0.51 | 46.0 | 3.57e-01 | 100.0% | 97.5% |
| 5070523 | 4044.1.1.0 ↗ | alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins | 0.51 | 44.0 | 4.36e-01 | 94.4% | 93.7% |
D2
medium
residues 197-293
Domain cluster:
rep: ON911539.2__UVB03021.1__IVIADoCa2_44__00044__D204-320
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3kfwX03 | 1.20.58.1460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 44.0 | 4.95e-01 | 79.4% | 80.3% |
| 4c0eA01 | 1.25.40.790 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.70 | 63.0 | 4.51e-01 | 100.0% | 43.5% |
| 3k62A00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.65 | 54.0 | 3.57e-01 | 99.0% | 21.8% |
| 4hbdA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.63 | 55.0 | 4.14e-01 | 99.0% | 42.4% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.62 | 56.0 | 4.97e-01 | 100.0% | 85.1% |
| 5m9dA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 56.0 | 4.94e-01 | 99.0% | 68.8% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.61 | 43.0 | 4.50e-01 | 78.4% | 80.5% |
| 2i2oA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 53.0 | 4.20e-01 | 100.0% | 91.9% |
| 2lsgA00 | 1.20.58.1280 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DNA repair protein Rev1, C-terminal domain | 0.60 | 49.0 | 4.95e-01 | 91.8% | 88.7% |
| 4hz4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 53.0 | 5.14e-01 | 100.0% | 92.9% |
| 3zheA02 | 1.25.40.760 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 52.0 | 4.16e-01 | 99.0% | 50.7% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 45.0 | 4.33e-01 | 78.4% | 81.5% |
| 7dvqK01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.59 | 48.0 | 4.05e-01 | 99.0% | 50.3% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 38.0 | 4.00e-01 | 80.4% | 72.9% |
| 3ztaA00 | 1.10.490.130 | Mainly Alpha › Orthogonal Bundle › Globin-like › | 0.59 | 46.0 | 4.14e-01 | 85.6% | 69.1% |
| 3peuB00 | 1.25.40.510 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › GLE1-like | 0.59 | 52.0 | 3.76e-01 | 100.0% | 39.0% |
| 2fonA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 36.0 | 3.32e-01 | 85.6% | 45.7% |
| 3ismC01 | 1.25.40.240 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ku, C-terminal domain | 0.58 | 51.0 | 4.41e-01 | 99.0% | 90.3% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 43.0 | 4.20e-01 | 78.4% | 80.4% |
| 3qwwA03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 48.0 | 3.88e-01 | 99.0% | 47.1% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.57 | 33.0 | 3.93e-01 | 92.8% | 88.5% |
| 2np3A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 44.0 | 3.95e-01 | 85.6% | 69.0% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 43.0 | 3.81e-01 | 79.4% | 66.2% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.56 | 43.0 | 4.62e-01 | 85.6% | 97.6% |
| 3jq0A00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 48.0 | 3.12e-01 | 100.0% | 87.0% |
| 4epzA00 | 1.25.40.810 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ | 0.55 | 48.0 | 4.20e-01 | 100.0% | 74.7% |
| 2cwqA00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.55 | 43.0 | 3.99e-01 | 87.6% | 65.9% |
| 1m4rB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.54 | 38.0 | 3.38e-01 | 73.2% | 79.4% |
| 3s63A00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.54 | 33.0 | 3.47e-01 | 70.1% | 67.0% |
| 6ofsA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.54 | 40.0 | 3.14e-01 | 80.4% | 83.6% |
| 4b94A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 46.0 | 4.17e-01 | 100.0% | 99.3% |
| 3vwaA03 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.53 | 46.0 | 3.34e-01 | 100.0% | 32.2% |
| 1sqgA01 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.53 | 42.0 | 3.68e-01 | 83.5% | 85.8% |
| 3qkxB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 40.0 | 3.36e-01 | 82.5% | 80.1% |
| 3go9A02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.53 | 40.0 | 3.10e-01 | 80.4% | 81.6% |
| 2i2xB01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.52 | 41.0 | 4.16e-01 | 87.6% | 86.0% |
| 7ocsB01 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.52 | 44.0 | 3.77e-01 | 99.0% | 93.1% |
| 3kh1A00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.52 | 44.0 | 3.50e-01 | 92.8% | 86.7% |
| 3he0B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 45.0 | 3.76e-01 | 100.0% | 64.6% |
| 5l0wB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 44.0 | 4.01e-01 | 100.0% | 85.5% |
| 2wauA01 | 1.20.1310.20 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain | 0.51 | 44.0 | 3.88e-01 | 100.0% | 100.0% |
| 2f07B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 39.0 | 3.23e-01 | 84.5% | 77.6% |
| 3tjzB00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.51 | 46.0 | 3.38e-01 | 100.0% | 46.6% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 38.0 | 3.87e-01 | 79.4% | 84.9% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3187773 | 109.4.1.441 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TFCD_C | 0.71 | 63.0 | 4.17e-01 | 100.0% | 30.6% |
| 4027953 | 109.4.1.85 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nop52 | 0.67 | 60.0 | 4.34e-01 | 100.0% | 42.5% |
| 3679487 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 57.0 | 4.31e-01 | 99.0% | 51.6% |
| 3730603 | 109.4.1.2140 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, TPR_30 | 0.62 | 55.0 | 3.25e-01 | 100.0% | 11.8% |
| 3809175 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 54.0 | 3.94e-01 | 99.0% | 40.0% |
| 3361374 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 52.0 | 4.31e-01 | 100.0% | 51.1% |
| 3725615 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.61 | 40.0 | 4.36e-01 | 81.4% | 81.2% |
| 3838401 | 192.10.1.0 ↗ | alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain | 0.61 | 39.0 | 3.91e-01 | 100.0% | 63.0% |
| 3238623 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.60 | 48.0 | 3.41e-01 | 85.6% | 45.8% |
| 3599610 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 54.0 | 3.30e-01 | 99.0% | 23.9% |
| 3601174 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 54.0 | 3.39e-01 | 100.0% | 22.3% |
| 3767517 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 53.0 | 4.50e-01 | 99.0% | 70.0% |
| 5046003 | 4070.1.1.0 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like | 0.60 | 50.0 | 4.04e-01 | 91.8% | 91.6% |
| 4980132 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.60 | 53.0 | 3.34e-01 | 100.0% | 20.2% |
| 3720908 | 109.4.1.22 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N | 0.59 | 52.0 | 3.57e-01 | 95.9% | 37.0% |
| 3608893 | 109.4.1.1201 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RESC6 | 0.59 | 53.0 | 3.62e-01 | 100.0% | 33.4% |
| 3781815 | 109.4.1.1561 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_LAA1_C | 0.58 | 52.0 | 4.42e-01 | 100.0% | 62.5% |
| 3650927 | 109.4.1.170 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CLASP_N | 0.58 | 51.0 | 4.27e-01 | 100.0% | 76.0% |
| 3577836 | 109.4.1.22 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N | 0.58 | 51.0 | 4.12e-01 | 96.9% | 68.1% |
| 4523691 | 109.4.1.337 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Ipi1_N | 0.58 | 52.0 | 3.71e-01 | 100.0% | 45.2% |
| 3986875 | 4254.1.1.1 ↗ | alpha arrays › YoaC-like › YoaC-like › YoaC-like › DUF1889 | 0.58 | 41.0 | 4.53e-01 | 83.5% | 98.6% |
| 3541655 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.58 | 44.0 | 4.08e-01 | 79.4% | 75.8% |
| 4595962 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 51.0 | 3.16e-01 | 100.0% | 20.6% |
| 3741923 | 109.4.1.335 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SEN1_N | 0.58 | 52.0 | 4.17e-01 | 100.0% | 75.8% |
| 3539252 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.57 | 49.0 | 4.10e-01 | 96.9% | 61.1% |
| 3460046 | 109.62.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › AFF4 C-terminal homology domain › AFF4 C-terminal homology domain › THD_CWZF3-5-7 | 0.57 | 50.0 | 3.92e-01 | 100.0% | 72.7% |
| 5075152 | 4033.1.1.1 ↗ | alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N | 0.57 | 44.0 | 4.31e-01 | 85.6% | 77.3% |
| 4027146 | 109.4.1.362 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_8 | 0.57 | 44.0 | 3.66e-01 | 94.8% | 45.8% |
| 3627403 | 109.4.1.1255 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N, Cnd1 | 0.56 | 49.0 | 3.28e-01 | 100.0% | 39.5% |
| 3900969 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.56 | 41.0 | 3.95e-01 | 78.4% | 80.0% |
| 59849 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 43.0 | 3.83e-01 | 94.8% | 54.7% |
| 3806925 | 109.4.1.1255 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N, Cnd1 | 0.56 | 49.0 | 3.01e-01 | 100.0% | 57.7% |
| 4467849 | 109.4.1.3080 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29795 | 0.56 | 50.0 | 4.49e-01 | 100.0% | 89.6% |
| 3530477 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 48.0 | 4.06e-01 | 100.0% | 55.4% |
| 3724504 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 46.0 | 3.69e-01 | 93.8% | 63.5% |
| 4603334 | 7011.1.1.0 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain | 0.55 | 46.0 | 3.40e-01 | 94.8% | 36.1% |
| 3535922 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 41.0 | 3.54e-01 | 79.4% | 60.0% |
| 3729279 | 611.3.1.0 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.54 | 46.0 | 4.52e-01 | 93.8% | 90.5% |
| 3257076 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 46.0 | 4.06e-01 | 95.9% | 63.4% |
| 3707101 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 46.0 | 3.53e-01 | 100.0% | 55.2% |
| 3275510 | 109.4.1.271 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FAN1_TPR | 0.53 | 47.0 | 3.95e-01 | 99.0% | 77.1% |
| 4977418 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.52 | 37.0 | 3.57e-01 | 80.4% | 65.5% |
| 3592993 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.51 | 38.0 | 3.46e-01 | 79.4% | 85.9% |
| 3320986 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.50 | 43.0 | 2.95e-01 | 100.0% | 27.2% |
| 3898385 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.50 | 46.0 | 3.92e-01 | 99.0% | 95.3% |
D3
medium
residues 294-367
Domain cluster:
representative
CATH (64)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.84 | 78.0 | 7.08e-01 | 100.0% | 76.3% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.84 | 56.0 | 5.18e-01 | 70.3% | 56.0% |
| 5tqbB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.82 | 69.0 | 4.41e-01 | 90.5% | 24.1% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.82 | 73.0 | 6.01e-01 | 100.0% | 88.7% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.81 | 73.0 | 5.69e-01 | 98.6% | 63.6% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.81 | 55.0 | 5.96e-01 | 70.3% | 86.9% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.79 | 71.0 | 6.26e-01 | 100.0% | 95.4% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.79 | 57.0 | 5.86e-01 | 87.8% | 78.9% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.79 | 69.0 | 5.88e-01 | 95.9% | 88.9% |
| 1lm3B00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.79 | 70.0 | 6.08e-01 | 94.6% | 76.4% |
| 4r42A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.79 | 72.0 | 5.29e-01 | 100.0% | 83.4% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 68.0 | 6.26e-01 | 97.3% | 99.0% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.79 | 70.0 | 5.50e-01 | 97.3% | 65.3% |
| 3smtA02 | 3.90.1420.10 | Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain | 0.77 | 67.0 | 5.11e-01 | 94.6% | 95.7% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.77 | 67.0 | 5.31e-01 | 94.6% | 49.3% |
| 4abnA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.77 | 70.0 | 4.65e-01 | 100.0% | 90.0% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.76 | 69.0 | 5.98e-01 | 100.0% | 73.5% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.76 | 51.0 | 3.92e-01 | 70.3% | 31.9% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.76 | 69.0 | 5.03e-01 | 100.0% | 56.9% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.76 | 66.0 | 5.69e-01 | 98.6% | 72.5% |
| 4gouA03 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.75 | 65.0 | 4.77e-01 | 95.9% | 61.4% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.75 | 66.0 | 5.70e-01 | 98.6% | 77.6% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.75 | 66.0 | 5.86e-01 | 100.0% | 90.7% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.75 | 66.0 | 6.27e-01 | 100.0% | 89.7% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.74 | 62.0 | 4.58e-01 | 93.2% | 92.3% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.74 | 67.0 | 5.84e-01 | 100.0% | 92.7% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.74 | 65.0 | 5.54e-01 | 100.0% | 95.1% |
| 3fnbA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.73 | 65.0 | 5.59e-01 | 97.3% | 64.9% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.73 | 64.0 | 6.39e-01 | 100.0% | 93.5% |
| 2ehwA00 | 6.10.140.1220 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 62.0 | 5.30e-01 | 91.9% | 86.1% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 50.0 | 5.49e-01 | 71.6% | 98.3% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.72 | 62.0 | 6.21e-01 | 95.9% | 96.0% |
| 2rkkA01 | 1.25.40.270 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 | 0.72 | 65.0 | 5.06e-01 | 100.0% | 50.0% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 64.0 | 5.43e-01 | 100.0% | 82.0% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 61.0 | 4.56e-01 | 95.9% | 71.1% |
| 3efzB00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.71 | 61.0 | 4.37e-01 | 97.3% | 48.0% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.70 | 62.0 | 4.66e-01 | 100.0% | 58.3% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.70 | 60.0 | 5.28e-01 | 97.3% | 78.9% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 61.0 | 5.03e-01 | 95.9% | 64.6% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 60.0 | 5.60e-01 | 95.9% | 96.7% |
| 3n2oA03 | 1.20.58.930 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 60.0 | 5.55e-01 | 97.3% | 76.0% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.70 | 59.0 | 5.20e-01 | 100.0% | 68.9% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 59.0 | 4.37e-01 | 100.0% | 42.4% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 60.0 | 4.97e-01 | 100.0% | 68.7% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 59.0 | 5.09e-01 | 100.0% | 69.4% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.67 | 54.0 | 5.50e-01 | 90.5% | 97.3% |
| 4py6C00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.67 | 54.0 | 4.57e-01 | 89.2% | 71.7% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.67 | 60.0 | 4.53e-01 | 100.0% | 55.3% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.65 | 56.0 | 5.25e-01 | 100.0% | 97.8% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 44.0 | 3.18e-01 | 70.3% | 35.3% |
| 2dg8D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 56.0 | 4.32e-01 | 98.6% | 71.1% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 54.0 | 4.91e-01 | 95.9% | 79.4% |
| 4zvaA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.64 | 54.0 | 4.36e-01 | 94.6% | 86.6% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.64 | 54.0 | 4.30e-01 | 93.2% | 60.7% |
| 4epzA00 | 1.25.40.810 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ | 0.64 | 48.0 | 3.80e-01 | 85.1% | 39.0% |
| 2hjmA01 | 1.20.120.460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like | 0.64 | 57.0 | 5.41e-01 | 97.3% | 83.7% |
| 3pmcA00 | 1.10.490.70 | Mainly Alpha › Orthogonal Bundle › Globin-like › Histidine kinase N-terminal domain | 0.63 | 53.0 | 4.54e-01 | 98.6% | 95.5% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.62 | 53.0 | 3.93e-01 | 97.3% | 80.2% |
| 1c02A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.61 | 54.0 | 4.21e-01 | 100.0% | 67.5% |
| 2w31A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.61 | 50.0 | 4.10e-01 | 94.6% | 84.9% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.61 | 52.0 | 4.22e-01 | 100.0% | 53.2% |
| 1h97A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 47.0 | 3.90e-01 | 97.3% | 94.6% |
| 1cqxA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.56 | 50.0 | 3.92e-01 | 97.3% | 89.3% |
| 7kfuC02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.55 | 49.0 | 3.43e-01 | 98.6% | 47.2% |
ECOD (67)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3935017 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.85 | 79.0 | 7.67e-01 | 100.0% | 93.8% |
| 3926031 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.83 | 74.0 | 6.73e-01 | 95.9% | 77.9% |
| 54287 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.83 | 74.0 | 6.25e-01 | 95.9% | 85.2% |
| 3899960 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.82 | 75.0 | 6.76e-01 | 100.0% | 93.0% |
| 3817383 | 109.4.1.401 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NRDE-2 | 0.82 | 69.0 | 5.85e-01 | 94.6% | 57.4% |
| 5070360 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.82 | 53.0 | 4.06e-01 | 74.3% | 31.6% |
| 3407072 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.81 | 75.0 | 7.30e-01 | 100.0% | 95.0% |
| 3219385 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.81 | 73.0 | 4.71e-01 | 100.0% | 23.2% |
| 4004067 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.80 | 71.0 | 6.75e-01 | 95.9% | 90.6% |
| 3458224 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.80 | 73.0 | 6.34e-01 | 100.0% | 76.4% |
| 3592632 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.80 | 68.0 | 6.19e-01 | 90.5% | 81.1% |
| 4577904 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.80 | 71.0 | 6.92e-01 | 100.0% | 88.7% |
| 3478235 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.79 | 71.0 | 5.86e-01 | 98.6% | 75.0% |
| 3592177 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.78 | 68.0 | 6.99e-01 | 93.2% | 100.0% |
| 3715982 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.77 | 69.0 | 4.25e-01 | 97.3% | 18.5% |
| 4117498 | 4177.1.1.96 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › MSP1_C | 0.77 | 69.0 | 4.39e-01 | 100.0% | 38.4% |
| 4013484 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.77 | 69.0 | 4.98e-01 | 100.0% | 58.0% |
| 3829435 | 109.4.1.67 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RINT1_TIP1 | 0.76 | 68.0 | 3.85e-01 | 100.0% | 14.9% |
| 3676953 | 109.4.1.87 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec6 | 0.76 | 69.0 | 3.95e-01 | 100.0% | 14.6% |
| 3412498 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.75 | 66.0 | 4.57e-01 | 100.0% | 30.4% |
| 3807085 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.75 | 68.0 | 6.49e-01 | 98.6% | 95.3% |
| 4997044 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.75 | 62.0 | 5.49e-01 | 100.0% | 62.9% |
| 3628598 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.75 | 68.0 | 6.65e-01 | 100.0% | 97.5% |
| 3243299 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.75 | 63.0 | 6.43e-01 | 91.9% | 97.1% |
| 3217462 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.74 | 66.0 | 5.96e-01 | 100.0% | 91.0% |
| 4542751 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.74 | 66.0 | 5.14e-01 | 100.0% | 68.8% |
| 3823586 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.74 | 61.0 | 4.66e-01 | 94.6% | 39.4% |
| 3832084 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.74 | 64.0 | 6.43e-01 | 94.6% | 100.0% |
| 4955893 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.73 | 65.0 | 4.72e-01 | 100.0% | 38.5% |
| 3648998 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.73 | 63.0 | 6.02e-01 | 100.0% | 82.2% |
| 3535006 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.73 | 64.0 | 5.75e-01 | 98.6% | 74.3% |
| 3862009 | 3755.3.1.293 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › TBCA_PH | 0.73 | 64.0 | 4.92e-01 | 95.9% | 88.7% |
| 3342748 | 109.4.1.5 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 | 0.72 | 60.0 | 4.30e-01 | 94.6% | 31.9% |
| 3999040 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.71 | 62.0 | 4.79e-01 | 98.6% | 98.8% |
| 3363646 | 109.4.1.728 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 60.0 | 4.24e-01 | 94.6% | 30.9% |
| 3245731 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.71 | 62.0 | 6.12e-01 | 100.0% | 96.2% |
| 3949780 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.70 | 61.0 | 4.61e-01 | 100.0% | 43.2% |
| 4939273 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.69 | 59.0 | 6.04e-01 | 94.6% | 100.0% |
| 3389546 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.69 | 61.0 | 6.00e-01 | 100.0% | 93.8% |
| 3276944 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.69 | 58.0 | 5.79e-01 | 95.9% | 90.7% |
| 3188613 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.68 | 59.0 | 5.32e-01 | 94.6% | 76.0% |
| 3906208 | 604.7.1.12 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA_PH | 0.68 | 59.0 | 4.73e-01 | 95.9% | 98.6% |
| 5075806 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.68 | 56.0 | 5.54e-01 | 93.2% | 88.7% |
| 3497645 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.68 | 57.0 | 5.64e-01 | 94.6% | 91.3% |
| 5038239 | 3843.1.1.31 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q3 | 0.67 | 54.0 | 5.41e-01 | 94.6% | 86.7% |
| 5083949 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.67 | 46.0 | 3.81e-01 | 70.3% | 100.0% |
| 3627942 | 3755.4.1.1 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 | 0.67 | 46.0 | 3.50e-01 | 71.6% | 30.3% |
| 3592316 | 7014.1.1.0 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain | 0.67 | 55.0 | 3.66e-01 | 93.2% | 76.3% |
| 3880244 | 603.2.1.24 ↗ | alpha bundles › STAT-like › STAT › STAT › TBCA_PH | 0.67 | 58.0 | 4.57e-01 | 97.3% | 94.8% |
| 3971927 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.66 | 52.0 | 5.03e-01 | 85.1% | 77.4% |
| 3929572 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.65 | 57.0 | 5.49e-01 | 97.3% | 91.8% |
| 3592927 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.65 | 55.0 | 4.32e-01 | 93.2% | 74.2% |
| 4683274 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.64 | 50.0 | 4.94e-01 | 85.1% | 81.2% |
| 4839189 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.63 | 52.0 | 4.52e-01 | 95.9% | 68.9% |
| 4024570 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.63 | 55.0 | 5.10e-01 | 100.0% | 77.9% |
| 3404886 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.62 | 55.0 | 5.41e-01 | 98.6% | 97.5% |
| 3214140 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.60 | 52.0 | 4.75e-01 | 100.0% | 80.0% |
| 3470962 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.60 | 52.0 | 5.00e-01 | 100.0% | 94.1% |
| 3967813 | 5086.1.1.93 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA | 0.60 | 48.0 | 4.06e-01 | 90.5% | 100.0% |
| 4466220 | 106.1.1.7 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Protoglobin | 0.60 | 50.0 | 3.88e-01 | 100.0% | 88.9% |
| 3987006 | 5086.1.1.93 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA | 0.59 | 47.0 | 3.94e-01 | 90.5% | 100.0% |
| 4024393 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.59 | 51.0 | 5.07e-01 | 100.0% | 96.2% |
| 4010479 | 325.1.7.48 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25885 | 0.59 | 47.0 | 4.01e-01 | 90.5% | 100.0% |
| 3781089 | 3291.1.1.83 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Cmc1 | 0.59 | 40.0 | 3.48e-01 | 70.3% | 46.1% |
| 3166260 | 1.1.7.123 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25885 | 0.59 | 47.0 | 3.99e-01 | 90.5% | 100.0% |
| 3692194 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.57 | 49.0 | 4.87e-01 | 100.0% | 96.2% |
| 4326325 | 3579.1.1.6 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › MbhD+MbhE | 0.51 | 45.0 | 3.35e-01 | 98.6% | 40.0% |
D4
medium
residues 368-419
Domain cluster:
representative
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4hkaA02 | 1.10.287.3810 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.85 | 66.0 | 6.66e-01 | 84.6% | 84.3% |
| 2ii2A04 | 1.10.220.10 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin | 0.83 | 57.0 | 4.84e-01 | 71.2% | 100.0% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.80 | 48.0 | 3.98e-01 | 71.2% | 36.8% |
| 3rx6A00 | 1.20.58.1090 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer | 0.79 | 66.0 | 4.41e-01 | 96.2% | 25.1% |
| 1vw4L01 | 3.90.1030.10 | Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17 | 0.79 | 64.0 | 4.67e-01 | 88.5% | 42.2% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.78 | 61.0 | 4.40e-01 | 86.5% | 31.1% |
| 3e98B00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.77 | 67.0 | 4.66e-01 | 100.0% | 83.9% |
| 1cpqA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.76 | 62.0 | 4.59e-01 | 88.5% | 89.1% |
| 2au3A04 | 1.20.50.30 | Mainly Alpha › Up-down Bundle › Pheromone ER-1 › | 0.76 | 52.0 | 5.14e-01 | 71.2% | 80.0% |
| 1dt9A01 | 3.30.960.10 | Alpha Beta › 2-Layer Sandwich › Translation, Eukaryotic Peptide Chain Release Factor Subunit 1; Chain A › eRF1 domain 1 | 0.76 | 53.0 | 4.16e-01 | 73.1% | 37.1% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.75 | 65.0 | 5.36e-01 | 98.1% | 96.8% |
| 2ovjA00 | 1.10.555.10 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein | 0.73 | 51.0 | 3.39e-01 | 73.1% | 48.8% |
| 4q5rA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.73 | 59.0 | 4.68e-01 | 92.3% | 82.1% |
| 3ub8A00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.72 | 61.0 | 4.37e-01 | 98.1% | 83.4% |
| 2l1lB00 | 1.20.1440.250 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.70 | 50.0 | 3.79e-01 | 76.9% | 47.2% |
| 3vurA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.70 | 57.0 | 4.57e-01 | 96.2% | 78.8% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 55.0 | 4.07e-01 | 88.5% | 81.3% |
| 1rr7A02 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.68 | 48.0 | 4.94e-01 | 78.8% | 79.2% |
| 1d8cA01 | 3.20.20.360 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Malate synthase, domain 3 | 0.67 | 59.0 | 3.43e-01 | 100.0% | 64.3% |
| 1kl9A02 | 1.10.150.190 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 | 0.67 | 57.0 | 4.57e-01 | 90.4% | 97.8% |
| 3ppuB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 49.0 | 3.93e-01 | 90.4% | 82.3% |
| 3j27B00 | 1.10.8.970 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Flavivirus envelope glycoprotein M-like | 0.59 | 42.0 | 3.85e-01 | 76.9% | 73.6% |
| 3qqaA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 44.0 | 3.22e-01 | 88.5% | 73.0% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3550485 | 904.1.1.22 ↗ | few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain › zf-B_box, TRIM_CC | 0.90 | 76.0 | 4.91e-01 | 90.4% | 23.9% |
| 5041226 | 604.16.1.0 ↗ | alpha bundles › Spectrin repeat-like › Hypothetical membrane protein Ta0354, soluble domain › Hypothetical membrane protein Ta0354, soluble domain | 0.86 | 77.0 | 7.13e-01 | 98.1% | 87.7% |
| 3409567 | 3755.3.1.324 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 | 0.84 | 71.0 | 4.83e-01 | 90.4% | 29.1% |
| 3577937 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.80 | 66.0 | 5.06e-01 | 90.4% | 41.7% |
| 3989094 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.80 | 66.0 | 5.99e-01 | 90.4% | 85.7% |
| 3688281 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.80 | 69.0 | 5.70e-01 | 98.1% | 56.8% |
| 3564110 | 5001.1.1.11 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_4 | 0.79 | 64.0 | 3.93e-01 | 88.5% | 15.9% |
| 3183271 | 216.1.1.1 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › UQ_con | 0.79 | 63.0 | 4.19e-01 | 90.4% | 23.1% |
| 4156411 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.79 | 65.0 | 5.90e-01 | 90.4% | 85.7% |
| 3414399 | 5086.1.1.106 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF725 | 0.77 | 61.0 | 4.27e-01 | 88.5% | 27.6% |
| 3478006 | 198.1.1.1 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 | 0.77 | 54.0 | 4.72e-01 | 73.1% | 50.7% |
| 3653793 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.77 | 58.0 | 4.81e-01 | 80.8% | 50.0% |
| 4041347 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.77 | 66.0 | 5.15e-01 | 96.2% | 50.9% |
| 3186617 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.76 | 60.0 | 3.69e-01 | 88.5% | 14.2% |
| 3479094 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.76 | 62.0 | 4.01e-01 | 94.2% | 39.6% |
| 3733319 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.76 | 60.0 | 4.65e-01 | 88.5% | 40.9% |
| 4016578 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.76 | 59.0 | 4.77e-01 | 88.5% | 44.8% |
| 3723053 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.75 | 63.0 | 3.85e-01 | 90.4% | 16.8% |
| 3974197 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.75 | 57.0 | 5.06e-01 | 86.5% | 56.2% |
| 3971315 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.75 | 64.0 | 5.10e-01 | 96.2% | 53.3% |
| 3594304 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.74 | 63.0 | 3.98e-01 | 94.2% | 20.4% |
| 3823586 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.74 | 66.0 | 4.54e-01 | 100.0% | 61.8% |
| 3684136 | 604.1.1.154 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27021 | 0.73 | 58.0 | 4.63e-01 | 90.4% | 43.6% |
| 3447097 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.73 | 57.0 | 4.60e-01 | 90.4% | 43.6% |
| 3570403 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.72 | 57.0 | 4.32e-01 | 86.5% | 36.0% |
| 3276727 | 7558.1.1.1 ↗ | a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Acyltransferase | 0.71 | 60.0 | 3.69e-01 | 98.1% | 38.3% |
| 5077460 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 59.0 | 5.39e-01 | 94.2% | 100.0% |
| 3553580 | 2484.8.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Separase pseudo-protease domain (PPD) › Separase pseudo-protease domain (PPD) › Peptidase_C50 | 0.68 | 59.0 | 3.79e-01 | 100.0% | 30.8% |
| 3606138 | 6132.1.1.0 ↗ | alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain | 0.67 | 52.0 | 5.29e-01 | 84.6% | 98.0% |
| 3264401 | 6132.1.1.0 ↗ | alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain | 0.65 | 54.0 | 4.89e-01 | 98.1% | 90.7% |
| 4095475 | 377.1.1.2 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › Ribosomal_S14 | 0.54 | 38.0 | 3.29e-01 | 78.8% | 44.2% |
D5
medium
residues 420-518
Domain cluster:
representative
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3r2qA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 45.0 | 4.32e-01 | 75.8% | 75.2% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.62 | 44.0 | 4.20e-01 | 73.7% | 81.0% |
| 3ezxA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.61 | 48.0 | 5.09e-01 | 97.0% | 96.5% |
| 3bvoA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.59 | 42.0 | 4.50e-01 | 83.8% | 86.0% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.59 | 41.0 | 4.36e-01 | 71.7% | 83.5% |
| 3zgzA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.57 | 37.0 | 3.10e-01 | 71.7% | 36.7% |
| 6tqpA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.57 | 42.0 | 3.84e-01 | 78.8% | 61.8% |
| 3swhA01 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.57 | 50.0 | 4.28e-01 | 100.0% | 84.8% |
| 2zueA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.57 | 41.0 | 3.88e-01 | 75.8% | 68.9% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 38.0 | 4.20e-01 | 75.8% | 92.0% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 40.0 | 3.87e-01 | 74.7% | 83.9% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.55 | 38.0 | 3.98e-01 | 71.7% | 86.4% |
| 3qkyA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 45.0 | 3.41e-01 | 91.9% | 42.6% |
| 2vvyA01 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.54 | 43.0 | 3.97e-01 | 97.0% | 64.9% |
| 8eupK01 | 3.40.50.790 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Ribosomal protein L1/L10, domain II | 0.54 | 35.0 | 3.54e-01 | 100.0% | 64.1% |
| 2oifB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 39.0 | 3.49e-01 | 78.8% | 60.9% |
| 3n2oA03 | 1.20.58.930 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 41.0 | 4.19e-01 | 84.8% | 89.6% |
| 5ojcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 39.0 | 3.46e-01 | 79.8% | 59.7% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.52 | 31.0 | 3.30e-01 | 97.0% | 65.5% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.51 | 36.0 | 3.45e-01 | 71.7% | 62.1% |
| 2jpnA00 | 1.20.1280.210 | Mainly Alpha › Up-down Bundle › Monooxygenase › Uncharacterised protein UvsW.1 | 0.51 | 35.0 | 3.80e-01 | 74.7% | 88.6% |
| 1x3kA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 42.0 | 3.71e-01 | 91.9% | 68.7% |
| 3smtA02 | 3.90.1420.10 | Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain | 0.50 | 43.0 | 3.72e-01 | 98.0% | 86.6% |
| 3w6bB00 | 1.10.530.10 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.50 | 37.0 | 3.30e-01 | 79.8% | 66.7% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3715372 | 6110.1.1.1 ↗ | alpha superhelices › Linker domain of cytoplasmic dynein heavy chain › Linker domain of cytoplasmic dynein heavy chain › Linker domain of cytoplasmic dynein heavy chain › DHC_N2 | 0.62 | 49.0 | 3.48e-01 | 86.9% | 33.8% |
| 5051767 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.61 | 44.0 | 4.97e-01 | 91.9% | 100.0% |
| 3458224 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 41.0 | 4.04e-01 | 70.7% | 69.1% |
| None | — | 0.59 | 40.0 | 3.36e-01 | 71.7% | 41.1% | |
| 3935017 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.59 | 40.0 | 4.31e-01 | 71.7% | 86.3% |
| 3706306 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 44.0 | 4.21e-01 | 82.8% | 94.2% |
| 4988269 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.58 | 36.0 | 3.74e-01 | 74.7% | 65.3% |
| 5076243 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.58 | 45.0 | 4.72e-01 | 98.0% | 92.2% |
| 3887898 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 49.0 | 4.07e-01 | 96.0% | 95.1% |
| 3513297 | 611.3.1.0 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.57 | 48.0 | 4.85e-01 | 94.9% | 91.0% |
| 3711741 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 46.0 | 3.61e-01 | 88.9% | 81.4% |
| 3898349 | 4121.1.1.2 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like | 0.56 | 42.0 | 3.28e-01 | 80.8% | 61.7% |
| 3721910 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.56 | 48.0 | 3.16e-01 | 96.0% | 49.7% |
| 3394603 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 47.0 | 4.10e-01 | 99.0% | 65.6% |
| 3624728 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.54 | 37.0 | 3.92e-01 | 72.7% | 81.2% |
| 3598958 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 47.0 | 3.64e-01 | 99.0% | 55.7% |
| 4554985 | 3322.1.1.0 ↗ | alpha bundles › N-terminal domain in fatty acid synthase subunit beta › N-terminal domain in fatty acid synthase subunit beta › N-terminal domain in fatty acid synthase subunit beta | 0.54 | 46.0 | 4.30e-01 | 98.0% | 82.3% |
| 3720723 | 5059.1.1.8 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA | 0.52 | 40.0 | 3.40e-01 | 83.8% | 77.8% |
| 3317698 | 4991.1.1.0 ↗ | extended segments › Lag-3 N-terminal region › Lag-3 N-terminal region › Lag-3 N-terminal region | 0.52 | 43.0 | 3.48e-01 | 92.9% | 44.9% |
| 3733195 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.52 | 44.0 | 3.85e-01 | 97.0% | 93.8% |
| 3768053 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.52 | 38.0 | 3.31e-01 | 77.8% | 65.8% |
| 3952752 | 639.2.1.0 ↗ | alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) | 0.52 | 37.0 | 4.20e-01 | 85.9% | 100.0% |
| 3635080 | 109.4.1.1651 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_EMC2 | 0.51 | 43.0 | 3.12e-01 | 96.0% | 38.4% |
| 3471234 | 3832.1.1.1 ↗ | alpha bundles › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › DUF758 | 0.50 | 37.0 | 3.08e-01 | 78.8% | 89.2% |
D6
medium
residues 653-710
Domain cluster:
representative
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3arxA03 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.56 | 41.0 | 3.72e-01 | 82.8% | 100.0% |
| 2iz4A02 | 2.20.25.590 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.56 | 31.0 | 3.50e-01 | 98.3% | 71.4% |
| 1boxA00 | 3.10.450.30 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Microbial ribonucleases | 0.55 | 38.0 | 3.30e-01 | 100.0% | 45.3% |
| 1owqA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.54 | 38.0 | 3.71e-01 | 77.6% | 98.5% |
| 1yqfB00 | 3.10.280.10 | Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein | 0.52 | 31.0 | 2.22e-01 | 100.0% | 18.6% |
| 1ov3A02 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.51 | 34.0 | 3.50e-01 | 98.3% | 74.5% |
| 2mklC00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 37.0 | 3.07e-01 | 79.3% | 88.6% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3739551 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.61 | 33.0 | 3.78e-01 | 100.0% | 72.5% |
| 4174140 | 318.1.1.0 ↗ | a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 | 0.60 | 33.0 | 3.06e-01 | 100.0% | 36.3% |
| 5035450 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.58 | 47.0 | 4.06e-01 | 93.1% | 84.2% |
| 3665481 | 64.1.1.1 ↗ | beta meanders › WW domain-like › WW domain › WW domain › WW | 0.57 | 32.0 | 3.53e-01 | 100.0% | 66.7% |
| 4937515 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.57 | 47.0 | 4.13e-01 | 93.1% | 90.0% |
| 3404585 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.56 | 33.0 | 3.53e-01 | 87.9% | 68.0% |
| 5061180 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.55 | 44.0 | 3.84e-01 | 91.4% | 83.2% |
| 3947154 | 101.1.2.70 ↗ | alpha arrays › HTH › HTH › winged helix domain › PqqD | 0.53 | 31.0 | 2.75e-01 | 91.4% | 36.7% |
| 4202852 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.53 | 41.0 | 3.56e-01 | 93.1% | 81.0% |
| 3939202 | 284.2.1.0 ↗ | a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain | 0.53 | 36.0 | 3.58e-01 | 70.7% | 71.7% |
| 3706303 | 7556.1.1.1 ↗ | a/b three-layered sandwiches › Fe-only hydrogenase › Fe-only hydrogenase › Fe-only hydrogenase › Fe_hyd_lg_C | 0.53 | 43.0 | 2.64e-01 | 100.0% | 13.6% |
| 3028388 | 319.1.1.4 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › ArsA_HSP20 | 0.52 | 35.0 | 3.32e-01 | 98.3% | 58.3% |
| 4166572 | 2004.1.1.86 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › FeoB_N | 0.51 | 35.0 | 2.57e-01 | 84.5% | 24.7% |
| 4025894 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.51 | 43.0 | 3.62e-01 | 100.0% | 84.4% |
| 3824874 | 7541.1.1.1 ↗ | a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth | 0.51 | 39.0 | 2.83e-01 | 86.2% | 54.4% |
| 3522450 | 391.1.2.2 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related › PSP94 | 0.50 | 29.0 | 2.65e-01 | 98.3% | 37.5% |