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NC_048860.1__YP_009857394.1__HWD16_gp11__00011

Bact-Vir

NC_048860.1__YP_009857394.1__HWD16_gp11__00011

Identity

Accession:
NC_048860 ↗
Kingdom:
phage

Quality

93.2 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Burrovirus› Microbacterium_phage_Arete

TaxID: 2713257

Cluster

View cluster (32 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 427-501
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00476.27 best DNA_pol_A 36.5 4.00e-09 96.0% 16.5%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.66 52.0 4.20e-01 85.3% 45.8%
6qpqB00 1.10.10.580 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Structural maintenance of chromosome 1. Chain E 0.65 39.0 3.85e-01 72.0% 55.6%
4x0qA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.63 50.0 4.05e-01 85.3% 45.8%
1l8qA03 1.10.1750.10 Mainly Alpha › Orthogonal Bundle › Chromosomal Replication Initiator Protein Dnaa; Chain: A; › DnaA protein, C-terminal DNA-binding domain 0.52 33.0 2.93e-01 72.0% 44.9%
5xs2B02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.52 44.0 3.71e-01 96.0% 99.2%
2i53A01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.52 44.0 3.61e-01 96.0% 99.3%
1c9bA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.51 37.0 3.45e-01 100.0% 60.8%
3hh0A01 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.51 37.0 3.79e-01 77.3% 88.9%
3e98B00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.50 39.0 3.08e-01 88.0% 48.9%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4975020 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.92 86.0 6.92e-01 100.0% 56.3%
3001792 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.88 73.0 6.16e-01 88.0% 56.8%
4027630 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.87 75.0 6.31e-01 92.0% 57.5%
4456463 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.87 69.0 5.66e-01 92.0% 48.5%
3969341 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.87 65.0 5.38e-01 86.7% 47.2%
4237263 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.86 74.0 6.25e-01 92.0% 57.5%
4169333 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.85 67.0 5.57e-01 92.0% 50.4%
3333780 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.82 71.0 5.69e-01 100.0% 50.0%
3277186 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.81 62.0 5.17e-01 86.7% 48.8%
4876668 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.81 60.0 5.05e-01 85.3% 47.6%
3259994 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.80 70.0 5.78e-01 100.0% 55.4%
3562851 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.79 68.0 5.46e-01 100.0% 49.7%
3595646 4964.1.1.1 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.76 69.0 5.40e-01 100.0% 61.9%
2970332 4964.1.1.0 ↗ alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.73 57.0 4.62e-01 85.3% 46.2%
4848450 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.71 56.0 4.58e-01 85.3% 47.5%
4962468 101.1.2.925 ↗ alpha arrays › HTH › HTH › winged helix domain › DUF7344 0.63 44.0 3.93e-01 72.0% 59.0%
4985569 873.1.1.12 ↗ a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › PF27313 0.55 44.0 3.64e-01 93.3% 48.1%
3846955 198.1.1.10 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2, SapB_1, Saposin 0.55 32.0 3.20e-01 77.3% 53.8%
D2 high residues 518-635
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3zsjA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.51 39.0 3.78e-01 100.0% 69.6%
1w0pA02 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.51 41.0 2.85e-01 83.9% 32.4%
1c1fA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.50 40.0 3.82e-01 100.0% 73.3%
1so7A00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.50 40.0 2.82e-01 83.9% 35.2%
2jkbA02 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.50 40.0 2.80e-01 83.9% 34.8%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5042182 4210.1.1.0 ↗ a+b two layers › WGR domain › WGR domain › WGR domain 0.62 47.0 5.02e-01 95.8% 94.0%
3650186 7579.1.1.6 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.57 42.0 2.85e-01 76.3% 80.9%
3366964 5.1.4.94 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Det1 0.55 43.0 3.20e-01 83.1% 56.5%
4929084 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.55 44.0 3.07e-01 86.4% 46.3%
4078351 247.1.1.34 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › MBL_MAP1B 0.54 39.0 3.08e-01 72.9% 88.5%
3221209 2007.2.3.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.54 46.0 3.33e-01 93.2% 72.1%
3178847 12.3.1.36 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › DUF5127 0.53 41.0 3.07e-01 82.2% 79.3%
4864166 5.1.3.22 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › GSDH 0.53 42.0 3.39e-01 87.3% 54.3%
3385471 4998.1.1.0 ↗ beta sandwiches › Flagellar hook protein flgE D2 domain-like › Flagellar hook protein flgE D2 domain › Flagellar hook protein flgE D2 domain 0.52 47.0 4.39e-01 98.3% 95.9%
3570251 5.1.4.288 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › APEH_N 0.52 41.0 2.81e-01 83.9% 44.3%
3496018 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.52 40.0 2.65e-01 85.6% 20.0%
3937258 220.1.1.159 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_met_RdRP 0.52 41.0 3.40e-01 83.9% 53.7%
3915503 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.52 40.0 2.89e-01 82.2% 94.5%
3715746 213.1.1.0 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) 0.51 41.0 3.37e-01 84.7% 79.5%
3651373 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.51 45.0 3.19e-01 100.0% 86.2%
3634141 511.1.1.1 ↗ beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › HSP70 0.50 38.0 3.46e-01 81.4% 77.6%
2141099 5.1.3.22 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › GSDH 0.50 43.0 2.98e-01 98.3% 83.4%
D3 medium residues 15-153
PDB
Domain cluster: rep: hypothetical_protein_KM727_gp68__YP_010087708__Homarus_gammarus_nudivirus__2509616__D1-16_45-146
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7r0kB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.79 75.0 5.99e-01 100.0% 69.4%
2gv9A03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.76 70.0 5.93e-01 99.3% 87.3%
1d5aA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.76 71.0 6.01e-01 100.0% 76.5%
2f96A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.74 67.0 5.83e-01 95.7% 86.1%
7jw6A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.72 68.0 5.76e-01 100.0% 66.5%
7jw2A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.72 67.0 5.74e-01 99.3% 68.1%
3safB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.71 67.0 5.19e-01 99.3% 55.4%
4nlcA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.71 66.0 5.27e-01 100.0% 59.9%
4okeA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.67 60.0 5.72e-01 95.7% 88.7%
3obyA02 3.30.420.60 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2 0.58 40.0 4.45e-01 87.8% 89.9%
8dkrB01 3.30.420.240 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.55 50.0 4.25e-01 99.3% 86.5%
6a8mA01 3.40.350.10 Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain 0.55 47.0 4.39e-01 90.6% 85.4%
4ktwA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.51 42.0 4.10e-01 91.4% 88.1%
1cpyA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.50 41.0 3.11e-01 88.5% 82.8%
1ax4A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.50 35.0 2.87e-01 70.5% 69.8%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4034473 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.86 80.0 7.10e-01 97.8% 73.2%
5056095 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.80 68.0 5.95e-01 100.0% 61.8%
3313728 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 45.0 5.23e-01 70.5% 78.0%
4821698 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 65.0 6.42e-01 86.3% 82.2%
4992857 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.77 72.0 6.21e-01 100.0% 78.5%
4891100 2484.1.1.161 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.77 72.0 5.66e-01 100.0% 73.1%
3266621 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.77 64.0 6.05e-01 88.5% 86.1%
3585591 896.1.1.0 ↗ a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related 0.76 36.0 4.50e-01 82.0% 71.1%
5068716 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.76 71.0 5.33e-01 100.0% 51.9%
4939488 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.76 71.0 5.44e-01 99.3% 55.5%
5062619 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.75 70.0 6.14e-01 100.0% 76.0%
5028008 2484.1.1.132 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo2 0.75 70.0 6.24e-01 100.0% 85.8%
4355900 2484.1.1.177 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF2779 0.75 70.0 5.73e-01 100.0% 74.6%
5066483 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.74 67.0 6.23e-01 99.3% 78.2%
3598787 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.74 70.0 5.51e-01 100.0% 52.3%
4026151 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.74 66.0 5.66e-01 99.3% 62.4%
3435062 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.73 63.0 5.39e-01 99.3% 58.6%
3604297 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.73 67.0 6.12e-01 100.0% 77.7%
3818775 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.73 63.0 5.37e-01 99.3% 58.6%
3778350 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.72 68.0 5.38e-01 100.0% 53.1%
3922908 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.72 67.0 5.57e-01 99.3% 63.5%
2725515 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.72 67.0 5.66e-01 99.3% 65.3%
3440342 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.71 54.0 5.92e-01 96.4% 94.8%
3742269 2484.1.1.90 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DEDDh_C 0.71 65.0 5.64e-01 96.4% 76.5%
1187764 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.71 66.0 5.28e-01 100.0% 59.9%
4261005 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.71 66.0 5.26e-01 100.0% 59.6%
4486407 2484.1.1.36 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.71 65.0 5.75e-01 100.0% 69.7%
3236261 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.71 65.0 5.29e-01 99.3% 58.0%
3434621 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.70 66.0 5.14e-01 100.0% 54.6%
5041307 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.70 53.0 4.20e-01 78.4% 52.3%
3937354 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.69 64.0 5.32e-01 99.3% 61.3%
3209754 2484.1.1.45 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 0.69 62.0 4.71e-01 96.4% 77.4%
3997031 2484.1.1.20 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.69 63.0 5.33e-01 99.3% 62.2%
3685910 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.69 63.0 5.33e-01 99.3% 62.8%
3798192 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.69 63.0 5.28e-01 99.3% 60.9%
3927943 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.68 62.0 5.10e-01 100.0% 57.6%
3226291 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.56 40.0 4.22e-01 73.4% 85.6%
5069292 2484.1.1.38 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 0.55 42.0 4.52e-01 87.8% 94.8%
3222575 207.1.1.81 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.55 42.0 3.44e-01 79.9% 69.1%
4974007 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 41.0 4.34e-01 87.1% 89.2%
5051832 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 52.0 4.65e-01 100.0% 78.9%
5001282 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 39.0 3.86e-01 72.7% 99.3%
3744435 2484.1.1.104 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 0.53 48.0 3.78e-01 100.0% 90.0%
4933539 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.53 46.0 3.95e-01 94.2% 77.7%
4497431 2484.1.1.38 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 0.52 42.0 4.39e-01 87.8% 93.6%
4948698 2484.1.1.38 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 0.52 40.0 4.40e-01 85.6% 100.0%
4995140 2484.1.1.124 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.51 40.0 3.96e-01 82.0% 100.0%
4934194 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.51 45.0 3.97e-01 95.7% 80.5%
D4 medium residues 154-221
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1lqsL01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.52 40.0 3.49e-01 80.9% 76.0%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3286256 149.1.1.1 ↗ alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.57 48.0 3.21e-01 97.1% 62.0%
3519620 190.1.1.0 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box 0.57 50.0 4.32e-01 100.0% 78.2%
D5 medium residues 407-426_644-726
PDB
Domain cluster: representative
CATH (88)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bgxT05 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.89 72.0 6.77e-01 100.0% 71.3%
7e6gA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.74 68.0 5.98e-01 99.0% 86.6%
2kl8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.74 54.0 5.83e-01 89.3% 91.8%
6d9mA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.74 68.0 5.90e-01 99.0% 86.8%
2re1A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.74 51.0 5.88e-01 91.3% 100.0%
5xgbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.74 67.0 5.53e-01 99.0% 72.6%
6hbzA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.74 67.0 5.77e-01 99.0% 80.5%
6zxbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.73 67.0 5.96e-01 100.0% 91.7%
3hvaA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.73 67.0 5.69e-01 100.0% 80.2%
2ia0B02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.73 53.0 5.41e-01 93.2% 78.8%
2bj3D02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.72 52.0 5.79e-01 90.3% 95.1%
5zneA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 49.0 5.68e-01 89.3% 100.0%
5yppA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.71 53.0 5.60e-01 94.2% 87.8%
3onqA02 3.30.70.2730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 51.0 5.67e-01 94.2% 96.3%
2f1fA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.71 52.0 5.88e-01 92.2% 100.0%
2gqqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.71 51.0 5.60e-01 92.2% 91.8%
1u8sA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.71 55.0 5.96e-01 93.2% 100.0%
3rrkA03 3.30.70.2750 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 49.0 5.66e-01 99.0% 100.0%
3jcmH04 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.71 51.0 5.73e-01 94.2% 100.0%
6ifnA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.71 63.0 5.33e-01 97.1% 80.5%
3i4pA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.71 51.0 5.53e-01 92.2% 91.7%
5wm1A02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.71 61.0 6.02e-01 97.1% 87.2%
7qh2C03 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 51.0 5.75e-01 76.7% 100.0%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.70 59.0 5.51e-01 92.2% 75.4%
4oj3B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 52.0 5.42e-01 92.2% 85.3%
3ofgB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 54.0 5.81e-01 92.2% 96.6%
2lqjA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 57.0 5.94e-01 97.1% 96.8%
3l0gB01 3.90.1170.20 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Quinolinate phosphoribosyl transferase, N-terminal domain 0.69 58.0 5.51e-01 90.3% 78.0%
2nyiA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.69 52.0 5.75e-01 92.2% 100.0%
1q5yC00 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.69 51.0 5.57e-01 91.3% 96.3%
1yz7A02 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.69 55.0 5.81e-01 90.3% 97.8%
4pcqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.69 52.0 5.64e-01 93.2% 96.4%
1lxjA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 50.0 5.01e-01 91.3% 75.7%
3trgA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 51.0 5.28e-01 93.2% 86.2%
2ca9A02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.68 52.0 5.52e-01 90.3% 92.1%
2hhpA03 3.30.70.590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain 0.68 62.0 5.41e-01 100.0% 97.4%
1zr6A03 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.68 51.0 4.06e-01 90.3% 40.4%
2od4B01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 54.0 5.80e-01 90.3% 100.0%
3ewgA00 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.67 48.0 5.28e-01 91.3% 95.0%
2yweA03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.67 48.0 5.27e-01 90.3% 92.7%
3pm9A04 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 53.0 5.71e-01 96.1% 100.0%
2kjwA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.67 52.0 5.36e-01 92.2% 89.6%
1usmA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.66 45.0 5.05e-01 82.5% 93.5%
3p96A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.66 50.0 5.47e-01 96.1% 100.0%
4limA00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.66 58.0 3.96e-01 99.0% 63.0%
1sjrA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.66 51.0 5.06e-01 94.2% 78.7%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.66 57.0 4.86e-01 95.1% 66.5%
1q9jB01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.65 56.0 4.46e-01 95.1% 92.0%
2nn6G03 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.65 43.0 4.65e-01 81.6% 79.5%
1xkpB00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.65 49.0 4.64e-01 78.6% 80.2%
1tuaA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.65 46.0 4.95e-01 75.7% 89.3%
1vx7X00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.65 52.0 5.41e-01 86.4% 92.8%
2pd1A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 54.0 5.58e-01 94.2% 98.9%
2c5sA01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.65 56.0 4.66e-01 92.2% 92.3%
1iujA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 54.0 5.46e-01 90.3% 96.1%
1qd1A01 3.30.990.10 Alpha Beta › 2-Layer Sandwich › Formiminotransferase-cyclodeaminase; Chain B, domain 1 › Formiminotransferase, N-terminal subdomain 0.64 56.0 4.62e-01 94.2% 100.0%
2dgxA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 47.0 5.21e-01 90.3% 100.0%
2xhcA01 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.64 48.0 4.98e-01 97.1% 85.3%
2jvrA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 47.0 5.19e-01 91.3% 100.0%
2ahoB03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.64 50.0 5.33e-01 84.5% 100.0%
4bbyA05 3.30.300.330 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.64 58.0 5.75e-01 100.0% 100.0%
3mwbB03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.64 49.0 5.14e-01 92.2% 89.5%
3tviA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.63 55.0 4.77e-01 95.1% 71.1%
3c1mA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.63 55.0 4.69e-01 95.1% 81.7%
4p6qA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.63 45.0 5.05e-01 88.3% 100.0%
4dn9B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 51.0 5.23e-01 92.2% 91.8%
5t0oA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.62 51.0 5.19e-01 90.3% 92.2%
1q8kA03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.62 53.0 5.12e-01 93.2% 89.7%
2r7rA04 3.30.70.2480 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 57.0 4.90e-01 100.0% 89.2%
3gz7B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 52.0 5.39e-01 92.2% 99.0%
2cg8B02 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.62 53.0 4.85e-01 92.2% 95.5%
2vsqA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.62 52.0 4.11e-01 93.2% 86.3%
4dmzA02 3.30.70.2880 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 55.0 5.04e-01 99.0% 88.3%
1r8gA00 3.30.590.20 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › 0.61 53.0 3.65e-01 95.1% 61.4%
4mt1A02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.61 50.0 5.05e-01 89.3% 92.2%
2qyxB01 3.30.70.1360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › mj0159-like 0.61 46.0 4.59e-01 96.1% 77.1%
1js3A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.60 44.0 4.58e-01 78.6% 100.0%
2atzA00 3.90.920.20 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › HP0184-like 0.60 54.0 4.51e-01 100.0% 86.9%
3oz2A02 3.30.9.10 Alpha Beta › 2-Layer Sandwich › D-Amino Acid Oxidase; Chain A, domain 2 › D-Amino Acid Oxidase, subunit A, domain 2 0.59 46.0 4.04e-01 93.2% 54.4%
5yjlB01 3.30.460.30 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Glutamyl-tRNA reductase, N-terminal domain 0.59 49.0 4.30e-01 93.2% 67.1%
2r4fA03 3.30.70.420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain 0.58 49.0 4.75e-01 95.1% 94.9%
2p92A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.57 43.0 4.42e-01 84.5% 88.4%
1s12A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.56 42.0 4.39e-01 87.4% 89.4%
1x31B02 3.30.9.10 Alpha Beta › 2-Layer Sandwich › D-Amino Acid Oxidase; Chain A, domain 2 › D-Amino Acid Oxidase, subunit A, domain 2 0.54 42.0 3.76e-01 94.2% 56.5%
3pgvA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.53 40.0 4.03e-01 79.6% 94.1%
1sezA02 3.90.660.20 Alpha Beta › Alpha-Beta Complex › Polyamine Oxidase; Chain A, domain 2 › Protoporphyrinogen oxidase, mitochondrial; domain 2 0.52 45.0 3.77e-01 97.1% 95.7%
3dh3A02 3.30.2350.10 Alpha Beta › 2-Layer Sandwich › Pseudouridine synthase › Pseudouridine synthase 0.51 44.0 3.71e-01 97.1% 56.4%
1ct9A01 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.50 40.0 3.28e-01 85.4% 93.2%
ECOD (99)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5036213 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.76 56.0 6.01e-01 91.3% 88.9%
3386929 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 67.0 5.83e-01 100.0% 83.2%
4929139 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.73 54.0 5.77e-01 91.3% 87.8%
5078653 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.73 54.0 5.85e-01 91.3% 92.9%
5000514 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.72 58.0 6.21e-01 87.4% 100.0%
3617015 304.120.1.12 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › PF26955 0.72 56.0 6.13e-01 95.1% 100.0%
4613881 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.72 53.0 5.73e-01 91.3% 89.8%
4048556 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.72 53.0 5.64e-01 91.3% 87.8%
4440255 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.72 53.0 5.67e-01 91.3% 88.8%
4081394 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.72 51.0 5.60e-01 92.2% 90.6%
4154211 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.71 53.0 5.60e-01 91.3% 87.8%
4021490 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.71 52.0 5.78e-01 93.2% 98.8%
5030091 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.71 55.0 6.02e-01 90.3% 100.0%
3948852 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.71 52.0 5.58e-01 91.3% 87.8%
5051000 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.71 51.0 5.61e-01 91.3% 92.8%
5056106 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.71 52.0 5.64e-01 91.3% 89.8%
4934098 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.71 55.0 5.95e-01 87.4% 100.0%
302769 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.70 52.0 5.46e-01 92.2% 84.2%
4223798 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.70 51.0 5.46e-01 90.3% 86.7%
4991207 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.70 52.0 5.55e-01 91.3% 88.9%
5039693 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.70 55.0 5.86e-01 93.2% 95.5%
5001014 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.70 52.0 5.62e-01 91.3% 92.9%
4977318 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.70 55.0 5.82e-01 94.2% 94.4%
5042195 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.70 56.0 5.87e-01 92.2% 95.7%
4985071 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.70 57.0 5.86e-01 95.1% 91.9%
4940108 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.70 55.0 5.88e-01 92.2% 97.8%
148700 304.12.1.2 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › MgtC_SapB_C 0.70 57.0 5.94e-01 97.1% 96.8%
4328360 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.70 51.0 5.47e-01 91.3% 88.9%
3236477 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.69 52.0 4.82e-01 92.2% 62.3%
3232695 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.69 51.0 5.07e-01 92.2% 75.2%
4954911 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.69 53.0 5.81e-01 94.2% 98.8%
330634 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.69 53.0 5.65e-01 93.2% 93.4%
3288914 304.6.1.1 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.69 59.0 4.42e-01 94.2% 40.0%
4669919 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.69 53.0 5.78e-01 89.3% 100.0%
4385553 304.48.1.48 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.69 63.0 5.35e-01 100.0% 77.6%
4926794 304.17.1.2 ↗ a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN 0.68 50.0 5.37e-01 94.2% 91.8%
3310133 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.68 56.0 5.99e-01 97.1% 100.0%
4050880 304.17.1.2 ↗ a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN 0.68 49.0 5.47e-01 95.1% 97.5%
4131480 304.162.1.1 ↗ a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.68 50.0 5.55e-01 89.3% 98.8%
4217144 304.162.1.1 ↗ a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.68 50.0 5.58e-01 88.3% 100.0%
4997522 304.12.1.0 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 0.68 50.0 5.54e-01 90.3% 100.0%
4220559 304.162.1.1 ↗ a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.68 50.0 5.59e-01 88.3% 100.0%
3949119 304.48.1.48 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.68 63.0 5.31e-01 100.0% 72.7%
4613556 304.28.1.13 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL 0.67 58.0 5.26e-01 93.2% 78.5%
3712842 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.67 61.0 5.02e-01 100.0% 68.3%
4994637 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.67 52.0 5.32e-01 97.1% 86.0%
5030195 304.17.1.2 ↗ a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN 0.66 48.0 5.09e-01 93.2% 86.7%
3367924 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.66 58.0 5.49e-01 94.2% 90.0%
3716499 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.66 60.0 4.65e-01 100.0% 52.4%
3445332 304.8.1.21 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.66 51.0 5.26e-01 93.2% 88.4%
3385766 304.28.1.2 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sec_GG 0.66 50.0 5.35e-01 97.1% 92.2%
5016775 304.122.1.1 ↗ a+b two layers › Alpha-beta plaits › Nitrogen repressor-like proteins › Nitrogen repressor-like proteins › NRD1_2 0.66 48.0 4.84e-01 96.1% 75.2%
3660837 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.66 50.0 5.38e-01 81.6% 96.5%
3675774 304.8.1.45 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.66 49.0 5.28e-01 78.6% 94.1%
3191211 304.8.1.21 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.66 51.0 5.49e-01 93.2% 100.0%
3807253 304.8.1.45 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.66 47.0 5.17e-01 76.7% 95.0%
3425342 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.66 46.0 5.30e-01 75.7% 100.0%
3802360 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.66 57.0 5.55e-01 96.1% 89.6%
3937461 304.151.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase 0.65 55.0 5.44e-01 92.2% 95.5%
3302370 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 46.0 5.05e-01 76.7% 90.4%
4988829 304.110.1.1 ↗ a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase 0.65 52.0 5.16e-01 94.2% 81.8%
4930463 304.17.1.2 ↗ a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN 0.65 48.0 5.08e-01 95.1% 88.9%
3832146 304.8.1.68 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › DUF493 0.65 51.0 5.33e-01 89.3% 90.5%
3378122 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.65 56.0 5.23e-01 95.1% 82.3%
3421851 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.65 58.0 5.44e-01 99.0% 93.6%
3290113 304.8.1.13 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_PSP_2 0.65 49.0 5.31e-01 93.2% 98.8%
3434168 304.8.1.45 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.65 45.0 4.55e-01 73.8% 71.4%
4929771 304.151.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase 0.64 49.0 5.29e-01 91.3% 100.0%
3784881 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.64 53.0 5.52e-01 94.2% 97.9%
4154765 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.63 51.0 5.32e-01 88.3% 96.8%
3815555 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.63 57.0 5.18e-01 98.1% 88.9%
3365716 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.63 46.0 4.96e-01 82.5% 92.9%
3482851 304.9.1.23 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_5 0.63 50.0 4.81e-01 95.1% 74.2%
3330441 304.8.1.45 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.63 44.0 5.01e-01 75.7% 100.0%
999861 304.4.1.4 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.63 50.0 5.18e-01 92.2% 90.7%
3958388 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 56.0 5.33e-01 99.0% 86.7%
4341311 304.8.1.45 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.62 46.0 4.84e-01 83.5% 87.8%
3511024 304.28.1.1 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran 0.62 54.0 5.47e-01 96.1% 98.0%
4967469 304.110.1.1 ↗ a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase 0.62 53.0 5.16e-01 94.2% 88.7%
4204243 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.62 47.0 3.11e-01 93.2% 18.7%
3643150 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.62 45.0 4.81e-01 81.6% 91.8%
3838844 304.18.1.1 ↗ a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS › FDX-ACB 0.62 50.0 5.24e-01 88.3% 95.7%
4575908 304.8.1.53 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › GlnD_5th 0.62 47.0 4.45e-01 81.6% 87.2%
3515820 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.61 51.0 5.05e-01 95.1% 86.4%
3365317 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 44.0 4.80e-01 77.7% 96.2%
3584599 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.61 53.0 5.20e-01 96.1% 96.4%
3273510 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 55.0 3.39e-01 100.0% 62.3%
3456962 304.8.1.45 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.60 43.0 4.71e-01 85.4% 92.9%
3680344 304.8.1.9 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_6 0.59 53.0 4.93e-01 96.1% 79.2%
4194812 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.59 45.0 4.35e-01 82.5% 91.7%
5032935 304.8.1.112 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › MazE_antitoxin 0.59 52.0 4.74e-01 97.1% 74.1%
3667160 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 50.0 5.05e-01 93.2% 97.0%
5581 306.8.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › TM1457-like › TM1457-like › Peptidase_Prp 0.58 45.0 4.46e-01 85.4% 87.5%
3399731 3016.1.1.21 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › PDXDC1-like_cen 0.58 44.0 3.90e-01 81.6% 78.7%
3279488 304.48.1.48 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.58 52.0 4.46e-01 100.0% 74.5%
3958967 304.154.1.0 ↗ a+b two layers › Alpha-beta plaits › Regulator of polyketide synthase expression N-terminal domain › Regulator of polyketide synthase expression N-terminal domain 0.57 51.0 4.53e-01 100.0% 76.0%
3959139 304.48.1.48 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.57 50.0 4.46e-01 100.0% 74.0%
3364993 304.5.1.26 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › PF30953 0.50 45.0 4.42e-01 99.0% 95.5%
4943248 4956.1.1.0 ↗ a+b two layers › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.50 44.0 3.50e-01 99.0% 55.0%