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NC_049345.1__YP_009874055.1__HYO70_gp63__00063

Bact-Vir

NC_049345.1__YP_009874055.1__HYO70_gp63__00063

Identity

Accession:
NC_049345 ↗
Kingdom:
phage

Quality

63.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 173-344
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07486.18 best Hydrolase_2 77.5 1.70e-21 62.2% 81.7%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
185732 3374.1.1.2 a+b complex topology › spore cortex-lytic enzyme catalytic domain › spore cortex-lytic enzyme catalytic domain › spore cortex-lytic enzyme catalytic domain › Hydrolase_2 0.87 56.0 6.49e-01 80.8% 86.7%
4427237 3374.1.1.2 a+b complex topology › spore cortex-lytic enzyme catalytic domain › spore cortex-lytic enzyme catalytic domain › spore cortex-lytic enzyme catalytic domain › Hydrolase_2 0.76 54.0 6.12e-01 78.5% 91.9%
D2 high residues 349-434
PDB
Domain cluster: representative
CATH (41)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.82 61.0 5.94e-01 77.9% 76.6%
8sppA01 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.75 60.0 3.97e-01 87.2% 39.4%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.74 46.0 4.61e-01 83.7% 61.6%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 54.0 5.07e-01 77.9% 66.7%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 55.0 3.97e-01 83.7% 31.5%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 45.0 4.83e-01 82.6% 78.7%
3gi8C00 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.67 53.0 3.41e-01 87.2% 60.0%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.67 42.0 4.71e-01 72.1% 82.1%
2mx8A01 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.66 47.0 4.31e-01 74.4% 59.3%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 45.0 4.67e-01 76.7% 76.9%
2fgyA01 1.20.120.1310 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Carboxysome Shell Carbonic Anhydrase, N-terminal helical domain 0.66 49.0 4.57e-01 97.7% 63.6%
2no4A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.65 45.0 4.79e-01 73.3% 88.0%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 54.0 4.19e-01 89.5% 92.3%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.65 41.0 4.66e-01 77.9% 84.8%
1oj6A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.64 45.0 3.77e-01 73.3% 93.2%
5fglA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 51.0 3.94e-01 90.7% 56.0%
2c0kB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.62 44.0 3.66e-01 73.3% 91.3%
3ddhA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.62 42.0 4.39e-01 70.9% 85.2%
7p2yd01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.61 46.0 4.48e-01 81.4% 71.7%
3umgA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.61 43.0 4.65e-01 74.4% 100.0%
2vk9A04 1.10.274.80 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › 0.61 47.0 4.45e-01 84.9% 68.3%
1hlbA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.61 43.0 3.56e-01 74.4% 88.5%
1xo0A01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.61 42.0 3.87e-01 72.1% 65.8%
3umcD02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.60 42.0 4.40e-01 73.3% 88.5%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.60 49.0 4.74e-01 87.2% 100.0%
6tqpA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.59 40.0 3.49e-01 70.9% 45.6%
2zcxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 49.0 3.75e-01 93.0% 48.8%
4hkaA01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 50.0 3.43e-01 93.0% 48.6%
2oxlA00 1.20.5.5260 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.58 39.0 4.39e-01 70.9% 96.8%
4c0eA01 1.25.40.790 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.58 42.0 2.94e-01 76.7% 45.9%
1x42A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.58 41.0 4.19e-01 74.4% 77.1%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 46.0 4.28e-01 87.2% 95.5%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.57 45.0 3.97e-01 84.9% 66.1%
3frqB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 47.0 3.65e-01 88.4% 49.5%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.56 42.0 3.69e-01 79.1% 84.4%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.55 40.0 4.03e-01 79.1% 78.8%
1yhuB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 38.0 3.29e-01 74.4% 95.1%
1z21A00 1.10.10.1000 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Type III secretion system virulence factor YopR, core domain 0.54 41.0 4.00e-01 82.6% 81.2%
1zp2A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.54 37.0 3.40e-01 73.3% 54.5%
3sqnA02 1.10.1790.40 Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › 0.53 39.0 3.53e-01 77.9% 99.2%
2jbyA00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.52 36.0 3.25e-01 74.4% 48.8%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5078328 2004.5.1.0 a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain 0.81 61.0 4.62e-01 83.7% 35.8%
5069732 545.1.2.0 alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Sporozoite protein UIS3 soluble domain 0.76 54.0 5.58e-01 74.4% 85.0%
3715373 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.76 61.0 5.18e-01 87.2% 73.6%
2774528 3286.1.1.1 alpha complex topology › Glypican insertion domain › Glypican insertion domain › Glypican insertion domain › Glypican 0.76 53.0 4.34e-01 72.1% 87.0%
5050035 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.75 67.0 5.18e-01 100.0% 66.7%
5020110 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.75 52.0 4.94e-01 79.1% 61.0%
3628013 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.73 58.0 4.21e-01 83.7% 32.7%
3657123 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.72 54.0 5.25e-01 86.0% 70.5%
3839497 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.72 46.0 4.64e-01 83.7% 65.9%
3181110 5086.1.1.110 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HisKA 0.69 50.0 4.90e-01 90.7% 68.4%
3169408 101.1.17.2 alpha arrays › HTH › HTH › FF domain › FF 0.67 48.0 5.27e-01 75.6% 92.9%
4624818 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.67 52.0 5.12e-01 82.6% 96.7%
3510771 610.4.1.0 alpha arrays › ERP29 C domain-like › YqeY domain › YqeY domain 0.67 46.0 4.39e-01 70.9% 74.0%
3798489 164.1.1.0 alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II 0.67 59.0 5.43e-01 96.5% 83.6%
3637653 3755.3.1.481 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF30554 0.67 53.0 4.28e-01 83.7% 70.3%
3958582 101.1.1.282 alpha arrays › HTH › HTH › Three-helical HTH › DUF222 0.66 55.0 4.66e-01 93.0% 53.3%
3791819 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.65 52.0 5.36e-01 84.9% 92.5%
4586684 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 58.0 5.01e-01 97.7% 86.2%
4589611 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.65 51.0 3.98e-01 87.2% 51.3%
1931178 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.65 43.0 3.61e-01 70.9% 39.9%
3782089 1065.1.1.0 alpha bundles › SPX domain › SPX domain › SPX domain 0.64 58.0 4.61e-01 97.7% 76.4%
3286277 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.63 41.0 3.22e-01 74.4% 31.7%
3329178 4953.1.1.24 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › Tim17 0.63 48.0 4.98e-01 81.4% 96.2%
4934479 2006.1.1.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.62 45.0 3.34e-01 74.4% 41.9%
3090483 2006.1.1.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.62 45.0 3.23e-01 75.6% 45.2%
144613 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.62 44.0 3.86e-01 74.4% 92.4%
3523978 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.62 44.0 3.83e-01 72.1% 70.4%
3503474 2006.1.1.44 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase, Hydrolase_like 0.61 43.0 3.16e-01 74.4% 41.6%
3715109 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 55.0 3.81e-01 100.0% 80.4%
4324903 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.59 45.0 3.82e-01 82.6% 84.0%
3589446 2004.1.1.301 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_27 0.59 47.0 2.97e-01 87.2% 15.8%
5036344 2006.1.1.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.58 41.0 3.00e-01 73.3% 31.9%
3737296 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.58 44.0 3.93e-01 83.7% 64.6%
5046548 2006.1.1.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.58 43.0 3.13e-01 79.1% 65.4%
3430097 2006.1.1.44 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase, Hydrolase_like 0.57 42.0 3.07e-01 88.4% 26.7%
4933807 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.57 40.0 4.03e-01 75.6% 74.1%
3583440 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.56 48.0 4.38e-01 97.7% 94.2%
4517375 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.56 45.0 4.19e-01 86.0% 90.9%
3758972 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.56 45.0 4.15e-01 86.0% 91.8%
4565108 109.4.1.1253 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Atp25_C 0.55 37.0 2.46e-01 74.4% 17.8%
3824504 2006.1.1.44 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase, Hydrolase_like 0.52 37.0 2.75e-01 75.6% 40.4%
4461240 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.52 36.0 3.17e-01 74.4% 95.2%
D3 medium residues 43-94
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.70 60.0 4.60e-01 100.0% 74.4%
1qo0D02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 35.0 3.77e-01 73.1% 58.7%
2ptfB02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.66 53.0 5.24e-01 94.2% 100.0%
8gy0A01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.66 56.0 3.57e-01 100.0% 30.6%
5afdA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.64 44.0 2.76e-01 73.1% 21.7%
1qsaA02 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.63 50.0 4.61e-01 94.2% 67.1%
2ofyA01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.63 44.0 3.97e-01 73.1% 95.7%
2da3A01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.62 46.0 4.82e-01 90.4% 91.5%
3ecsC01 1.20.120.1070 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Translation initiation factor eIF-2B, N-terminal domain 0.62 51.0 4.21e-01 96.2% 60.0%
1j78A05 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.62 41.0 3.95e-01 94.2% 60.0%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.61 42.0 3.71e-01 75.0% 50.6%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.60 49.0 4.27e-01 92.3% 77.1%
1axdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 46.0 3.68e-01 96.2% 72.4%
3kfwX03 1.20.58.1460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 48.0 4.36e-01 98.1% 84.2%
1vhnA02 1.10.1200.80 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Putative flavin oxidoreducatase; domain 2 0.58 47.0 4.30e-01 92.3% 84.5%
2p58C00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 47.0 3.74e-01 94.2% 42.9%
7odyC01 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.58 41.0 3.42e-01 82.7% 42.4%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 47.0 4.09e-01 100.0% 79.1%
2dk8A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 48.0 4.55e-01 98.1% 95.4%
4bojA00 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.58 49.0 3.02e-01 100.0% 21.1%
2aleA00 3.30.1330.30 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Ribosomal protein L30/S12 0.57 49.0 3.75e-01 100.0% 65.2%
1zq3P00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.56 44.0 4.07e-01 92.3% 67.6%
3qxyA02 3.90.1420.10 Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain 0.56 44.0 3.06e-01 86.5% 38.3%
3tahA02 1.10.287.1770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 41.0 3.53e-01 82.7% 48.9%
4a8eA01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.55 46.0 3.99e-01 98.1% 78.2%
1dvgA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.55 41.0 2.74e-01 80.8% 19.6%
5fhiA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 45.0 3.44e-01 100.0% 92.1%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.55 38.0 3.54e-01 73.1% 59.1%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 45.0 3.43e-01 94.2% 89.2%
7s0rB01 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.53 47.0 4.17e-01 100.0% 85.5%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 42.0 4.09e-01 100.0% 96.8%
3ihuA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.53 46.0 3.43e-01 100.0% 76.3%
3b9qA01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.52 43.0 3.75e-01 100.0% 62.9%
3mggA02 6.10.140.1580 Special › Helix non-globular › Helix Hairpins › 0.52 39.0 3.46e-01 90.4% 78.7%
1x4pA00 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.52 40.0 3.84e-01 94.2% 84.8%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5027495 192.12.1.0 alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM 0.74 67.0 5.63e-01 100.0% 91.8%
4028663 545.1.2.0 alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Sporozoite protein UIS3 soluble domain 0.74 63.0 4.97e-01 100.0% 61.7%
4937368 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.69 60.0 4.39e-01 96.2% 82.2%
3663500 109.4.1.1256 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 0.68 57.0 4.17e-01 98.1% 34.5%
5073671 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.67 56.0 4.37e-01 96.2% 74.2%
3570499 604.1.1.95 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › KIAA1755_C 0.67 55.0 4.71e-01 100.0% 86.3%
5026348 218.1.1.1 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › MR_MLE_N 0.67 57.0 5.03e-01 100.0% 71.2%
3363652 109.4.1.1365 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2, TPR_24 0.66 56.0 3.79e-01 100.0% 25.6%
5077593 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.66 57.0 4.18e-01 98.1% 77.9%
5017179 604.17.1.1 alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like › DUF447_C 0.65 48.0 4.94e-01 82.7% 100.0%
3588648 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.64 53.0 3.51e-01 96.2% 92.5%
4932863 101.1.2.947 alpha arrays › HTH › HTH › winged helix domain › PF27234 0.63 53.0 4.63e-01 96.2% 68.8%
3356221 4030.1.1.14 alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › ERAP1_C 0.63 49.0 4.30e-01 94.2% 55.3%
4796295 6102.1.1.1 alpha arrays › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › SMC_ScpA 0.63 50.0 4.68e-01 96.2% 87.0%
3869025 4030.1.1.3 alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › Exog_C 0.62 49.0 4.59e-01 92.3% 70.6%
3398024 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.62 52.0 4.39e-01 100.0% 83.2%
3386452 5050.1.1.21 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FTR1 0.62 50.0 3.75e-01 96.2% 84.1%
1268318 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.62 51.0 4.09e-01 100.0% 83.1%
3901765 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.61 45.0 4.03e-01 86.5% 83.5%
3789467 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.61 45.0 3.80e-01 82.7% 67.4%
3895121 4030.1.1.3 alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › Exog_C 0.61 51.0 4.88e-01 100.0% 81.0%
3615667 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 50.0 2.95e-01 100.0% 10.2%
3317418 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.58 47.0 4.29e-01 92.3% 98.6%
3496953 4030.1.1.0 alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.57 42.0 4.07e-01 80.8% 70.0%
3240699 101.1.1.75 alpha arrays › HTH › HTH › Three-helical HTH › HTH_48 0.57 47.0 4.34e-01 96.2% 78.6%
3712892 3676.1.1.4 alpha duplicates or obligate multimers › RNA helicase Hera dimerization domain › RNA helicase Hera dimerization domain › RNA helicase Hera dimerization domain › DD_DDX21-DDX50 0.56 39.0 3.83e-01 73.1% 89.1%
4988832 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.55 48.0 4.51e-01 100.0% 92.3%
3372396 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.54 44.0 4.03e-01 94.2% 72.9%
3588086 101.1.1.45 alpha arrays › HTH › HTH › Three-helical HTH › BrxA 0.54 44.0 4.11e-01 94.2% 83.1%
4008778 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.53 43.0 4.30e-01 96.2% 98.2%
3588719 564.1.1.0 alpha arrays › N-terminal, cytoplasmic domain of anti-sigma factors › N-terminal, cytoplasmic domain of anti-sigma factors › N-terminal, cytoplasmic domain of anti-sigma factors 0.52 44.0 4.17e-01 98.1% 90.8%
4854416 5071.1.1.1 alpha bundles › cytochrome bc1 complex 11 kDa protein-like › Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › UCR_hinge 0.52 36.0 3.46e-01 76.9% 64.1%
3934732 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.50 42.0 4.03e-01 100.0% 100.0%
3953824 628.1.1.1 alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD 0.50 41.0 3.21e-01 100.0% 79.3%
D4 medium residues 477-583
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2a7oA00 1.10.1740.100 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Set2, Rpb1 interacting domain 0.60 43.0 4.45e-01 75.7% 89.0%
3vkgA15 1.10.8.1220 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.56 38.0 3.98e-01 74.8% 78.7%
4hvlA00 3.40.50.200 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain 0.56 45.0 3.09e-01 86.0% 46.9%
4mndA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.55 47.0 3.95e-01 95.3% 91.1%
2vk9A03 1.10.3730.30 Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › 0.55 38.0 3.95e-01 72.0% 79.6%
7px0A01 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.54 37.0 3.59e-01 98.1% 62.5%
4gc0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 44.0 3.45e-01 95.3% 80.3%
2of5H00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.52 34.0 3.49e-01 81.3% 70.0%
4fp4A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.52 42.0 3.30e-01 89.7% 71.2%
2n3eA01 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.51 33.0 3.31e-01 71.0% 60.9%
2qvwC06 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.51 41.0 3.70e-01 88.8% 88.2%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.50 31.0 3.74e-01 70.1% 98.5%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3304703 4957.1.1.0 a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit 0.65 50.0 5.19e-01 81.3% 94.0%
3786619 103.4.1.2 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › TFIIS_M 0.63 49.0 5.14e-01 86.9% 93.7%
3637135 1128.1.1.0 alpha bundles › LYR protein › LYR protein › LYR protein 0.62 48.0 4.64e-01 81.3% 77.5%
3187931 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 48.0 3.21e-01 92.5% 82.1%
3491303 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.58 41.0 4.32e-01 74.8% 83.2%
3706616 2003.1.5.46 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.56 45.0 3.18e-01 86.9% 27.5%
3355967 5031.1.1.4 extended segments › Photosystem II reaction center protein J, PsbJ › Photosystem II reaction center protein J, PsbJ › Photosystem II reaction center protein J, PsbJ › Yip1 0.55 47.0 4.17e-01 96.3% 78.1%
4928737 592.2.1.0 alpha arrays › PWI domain-like › YugE-like › YugE-like 0.54 37.0 3.86e-01 77.6% 77.9%
3205075 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 42.0 3.32e-01 86.0% 40.8%
3941162 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 39.0 3.35e-01 75.7% 84.1%
3674246 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.53 40.0 3.70e-01 81.3% 70.7%
3685502 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 44.0 3.65e-01 95.3% 51.0%
4649431 3524.1.1.2 alpha arrays › Uncharacterized protein encoded by cryptic prophage › Uncharacterized protein encoded by cryptic prophage › Uncharacterized protein encoded by cryptic prophage › PF29794 0.52 37.0 3.80e-01 79.4% 78.8%
5046064 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 44.0 3.76e-01 97.2% 90.0%
4255175 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.51 41.0 3.19e-01 87.9% 64.2%
3920730 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.51 43.0 3.57e-01 95.3% 88.3%
3859773 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 45.0 3.85e-01 100.0% 97.2%
3945231 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 43.0 3.60e-01 96.3% 82.0%
3729604 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 3.60e-01 97.2% 82.9%
4987513 171.1.1.3 alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_2 0.50 43.0 4.14e-01 98.1% 100.0%
D5 medium residues 590-672
PDB