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NFkB_inhibitor

Euk-Vir

Cotia_virus_SPAn232

NFkB_inhibitor__YP_005296354__Cotia_virus_SPAn232__930275

Identity

Accession:
YP_005296354 ↗
Protein ID:
NFkB_inhibitor
Kingdom:
euk

Quality

91.9 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Oryzopoxvirus› Cotia_virus_SPAn232

TaxID: 930275

Cluster

View cluster (59 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 25-149
PDB
Domain cluster: rep: A52R-like_family_protein__YP_009408101__Eptesipox_virus__1329402__D82-206
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06227.18 best Poxv_Bcl-2-like 94.8 6.90e-27 95.2% 75.6%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2vvyA01 1.10.437.20 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus 0.97 94.0 9.16e-01 100.0% 93.3%
2vvwA00 1.10.437.20 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus 0.83 78.0 7.28e-01 100.0% 84.7%
4lqkA00 1.10.437.20 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus 0.78 69.0 6.77e-01 100.0% 87.9%
2k36A00 1.10.437.20 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus 0.78 72.0 6.70e-01 100.0% 81.2%
2kbwA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.74 68.0 6.35e-01 100.0% 94.8%
2aboA00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.70 64.0 6.37e-01 100.0% 97.7%
1ohuA00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.70 64.0 5.82e-01 100.0% 87.3%
2jbyA00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.69 61.0 6.14e-01 100.0% 95.3%
6tqpA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.68 62.0 6.06e-01 100.0% 96.3%
3ztaA00 1.10.490.130 Mainly Alpha › Orthogonal Bundle › Globin-like › 0.66 46.0 4.49e-01 71.2% 77.7%
1q59A00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.63 55.0 5.04e-01 100.0% 89.0%
3juiA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 42.0 3.82e-01 73.6% 82.2%
1j09A05 1.10.10.350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.59 39.0 4.31e-01 76.0% 84.7%
3qnfA04 1.10.3480.20 Mainly Alpha › Orthogonal Bundle › TorD-like › 0.59 41.0 3.65e-01 71.2% 52.5%
5bz1A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 40.0 2.85e-01 70.4% 39.4%
7ldgA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.56 39.0 3.27e-01 71.2% 40.9%
1b0bA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 39.0 3.80e-01 72.0% 77.3%
2lt3A01 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.56 37.0 4.11e-01 77.6% 85.0%
4fm3A00 1.20.1270.390 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 31.0 3.46e-01 92.0% 70.5%
4l3uA00 1.20.1480.40 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Uncharacterised protein PF16133, DUF4844 0.55 38.0 3.88e-01 71.2% 77.2%
3wctD00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 38.0 3.68e-01 72.8% 74.8%
7qihA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 32.0 3.46e-01 70.4% 69.3%
5ejrA01 1.25.40.530 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain 0.53 47.0 4.02e-01 96.8% 70.6%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 36.0 3.11e-01 71.2% 61.8%
1xo0A01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.52 39.0 4.08e-01 82.4% 89.2%
2wglA00 1.10.4190.10 Mainly Alpha › Orthogonal Bundle › Urease accessory protein UreF › Urease accessory protein UreF 0.52 39.0 3.32e-01 78.4% 61.2%
4yvoA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 36.0 3.69e-01 71.2% 95.8%
4x28A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.51 37.0 3.85e-01 73.6% 84.1%
3hyuA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.50 37.0 3.64e-01 78.4% 79.4%
1beoA00 1.10.239.10 Mainly Alpha › Orthogonal Bundle › Beta-cryptogein › Elicitin domain 0.50 36.0 3.91e-01 84.8% 94.9%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1157195 5000.3.1.3 ↗ alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Poxv_Bcl-2-like 0.97 94.0 8.91e-01 100.0% 88.0%
51371 5000.3.1.0 ↗ alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death 0.73 67.0 6.11e-01 100.0% 90.7%
2464246 5000.3.1.1 ↗ alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 0.72 66.0 6.24e-01 100.0% 93.2%
51373 5000.3.1.0 ↗ alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death 0.72 65.0 6.46e-01 98.4% 97.7%
3231057 5000.3.1.2 ↗ alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2,BH4 0.71 65.0 5.81e-01 100.0% 85.7%
4605105 5000.3.1.1 ↗ alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 0.71 64.0 5.68e-01 100.0% 78.3%
2488153 5000.3.1.1 ↗ alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 0.69 63.0 5.72e-01 100.0% 88.4%
5030376 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.64 45.0 3.80e-01 72.0% 95.7%
3316 5000.3.1.1 ↗ alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 0.63 55.0 5.04e-01 100.0% 89.0%
4997940 186.1.1.0 ↗ alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N 0.60 41.0 4.50e-01 79.2% 88.0%
3744899 5050.1.1.37 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Glucan_synthase 0.59 47.0 3.88e-01 86.4% 90.6%
4566333 186.1.1.1 ↗ alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 0.58 42.0 4.53e-01 81.6% 94.0%
4520087 186.1.1.1 ↗ alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 0.57 40.0 4.40e-01 78.4% 91.0%
3452645 101.35.1.31 ↗ alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › Gliadin 0.57 40.0 4.45e-01 78.4% 93.7%
4033979 5048.1.1.2 ↗ alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › Form_Nir_trans 0.56 41.0 3.33e-01 77.6% 83.8%
4278168 109.4.1.317 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med5 0.56 39.0 3.32e-01 71.2% 59.5%
3973571 601.3.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.55 34.0 3.60e-01 95.2% 67.8%
3973373 601.33.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.53 37.0 4.05e-01 96.8% 89.9%
3652677 601.18.1.13 ↗ alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Vwaint 0.53 35.0 3.64e-01 92.0% 71.3%
3711644 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 35.0 3.56e-01 70.4% 68.3%
4026666 2003.1.9.1 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF 0.52 46.0 3.20e-01 100.0% 36.7%
4439556 601.1.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.51 41.0 3.10e-01 95.2% 34.8%
3729011 601.1.1.90 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF3433 0.51 45.0 4.02e-01 97.6% 92.0%
3204406 601.11.1.2 ↗ alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › DUF3433 0.51 45.0 4.00e-01 97.6% 88.3%