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NFkB_inhibitor

Euk-Vir

Eptesipox_virus

NFkB_inhibitor__YP_009408124__Eptesipox_virus__1329402

Identity

Accession:
YP_009408124 ↗
Protein ID:
NFkB_inhibitor
Kingdom:
euk

Quality

62.8 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Vespertilionpoxvirus› Eptesipox_virus

TaxID: 1329402

Cluster

View cluster (18 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 30-162_189-224
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04887.18 best Pox_M2 52.1 8.40e-14 79.9% 69.9%
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4hkjD00 2.60.240.30 Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › 0.73 63.0 6.13e-01 90.5% 94.1%
1cq3A00 2.60.240.10 Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › Major secreted virus protein 0.72 62.0 5.54e-01 89.3% 98.7%
3on9A00 2.60.240.20 Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › 0.72 61.0 6.27e-01 88.2% 96.9%
2vgaA00 2.60.240.10 Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › Major secreted virus protein 0.69 58.0 5.56e-01 88.2% 96.4%
5t0oA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.65 40.0 5.01e-01 89.9% 100.0%
2cg9X01 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.64 35.0 4.45e-01 73.4% 89.0%
5zceA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.62 24.0 3.39e-01 71.6% 72.7%
5brqA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.61 25.0 3.48e-01 71.6% 75.3%
1wzaA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.59 23.0 3.24e-01 72.8% 72.2%
1m53A03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.59 23.0 3.26e-01 71.0% 74.0%
1uokA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.58 24.0 3.26e-01 74.0% 74.4%
2ze0A03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.57 21.0 3.10e-01 74.0% 72.2%
3uxfA02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.57 39.0 3.96e-01 87.0% 70.5%
1j0hA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.56 23.0 3.09e-01 73.4% 71.1%
4e1sA00 2.40.160.160 Mainly Beta › Beta Barrel › Porin › Inverse autotransporter, beta-domain 0.55 47.0 4.12e-01 89.3% 86.0%
3b5hA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 24.0 3.32e-01 76.9% 84.1%
3kl0D01 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.53 28.0 3.50e-01 76.3% 81.1%
1pzdA01 2.60.40.1480 Mainly Beta › Sandwich › Immunoglobulin-like › Coatomer, gamma subunit, appendage domain 0.53 33.0 3.42e-01 76.9% 66.7%
3dxpA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 27.0 3.50e-01 77.5% 89.2%
7zgmA01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.51 43.0 3.80e-01 89.9% 95.9%
4d6gA03 2.60.220.10 Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal 0.51 34.0 3.82e-01 74.0% 88.5%
3w9kA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.50 35.0 3.88e-01 96.4% 88.1%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
146301 527.1.1.3 ↗ beta sandwiches › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › CrmD_SECRET 0.72 61.0 6.27e-01 88.2% 96.9%
4855718 527.1.1.1 ↗ beta sandwiches › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › Orthopox_35kD 0.69 58.0 5.54e-01 88.2% 95.9%
3399963 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.63 36.0 4.18e-01 78.7% 76.7%
4082072 12.1.1.22 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › GH97_C 0.59 27.0 3.45e-01 78.7% 72.6%
3957060 325.1.6.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Duplicated hybrid motif › Peptidase_M23 0.59 35.0 3.74e-01 77.5% 66.2%
3266952 12.3.1.46 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › ComC_SSD 0.56 40.0 3.58e-01 71.6% 76.2%
3707402 12.6.1.1 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Glyco_hydro_65C 0.56 23.0 3.45e-01 79.9% 86.7%
3252383 12.3.1.46 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › ComC_SSD 0.55 38.0 3.45e-01 70.4% 76.2%
3223598 11.10.1.6 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like › MATH 0.54 31.0 3.37e-01 74.6% 65.0%
4393169 11.31.1.2 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Beta-galactosidase LacA beta-sandwich domain › Beta-galactosidase LacA beta-sandwich domain › GLMA-like_C 0.54 22.0 3.08e-01 78.7% 78.7%
4989818 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.53 45.0 4.11e-01 89.9% 99.5%
2717534 12.3.1.31 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › YgjK_N 0.53 45.0 3.79e-01 90.5% 82.5%
3962450 9.27.1.0 ↗ beta barrels › Lipocalins/Streptavidin › LpqH › LpqH 0.53 33.0 4.07e-01 84.0% 100.0%
3953943 9.27.1.1 ↗ beta barrels › Lipocalins/Streptavidin › LpqH › LpqH › Myco_19_kDa 0.52 33.0 3.97e-01 88.8% 97.3%
4964630 331.3.1.11 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 0.52 36.0 3.95e-01 78.7% 85.3%
5035423 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.51 27.0 3.60e-01 89.9% 100.0%
3223040 12.3.1.13 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C 0.51 38.0 3.32e-01 76.3% 96.9%