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NFkB_inhibitor
Euk-VirMurmansk_poxvirus
NFkB_inhibitor__YP_009408374__Murmansk_poxvirus__2025359
Identity
- Accession:
- YP_009408374 ↗
- Protein ID:
- NFkB_inhibitor
- Kingdom:
- euk
Quality
68.9
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Centapoxvirus›
Murmansk_poxvirus
TaxID: 2025359
Cluster
View cluster (18 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 35-218
Domain cluster:
rep: NFkB_inhibitor__YP_009408124__Eptesipox_virus__1329402__D30-162_189-224
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04887.18 best | Pox_M2 | 217.6 | 1.60e-64 | 100.0% | 94.4% |
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3on9A00 | 2.60.240.20 | Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › | 0.78 | 64.0 | 6.85e-01 | 100.0% | 97.5% |
| 4hkjD00 | 2.60.240.30 | Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › | 0.69 | 60.0 | 6.07e-01 | 100.0% | 91.9% |
| 1cq3A00 | 2.60.240.10 | Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › Major secreted virus protein | 0.66 | 62.0 | 5.81e-01 | 99.5% | 92.4% |
| 2vgaA00 | 2.60.240.10 | Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › Major secreted virus protein | 0.64 | 60.0 | 5.92e-01 | 98.9% | 95.4% |
| 5zceA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.62 | 22.0 | 3.32e-01 | 82.6% | 74.0% |
| 1uokA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.61 | 22.0 | 3.31e-01 | 84.8% | 74.4% |
| 5brqA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.60 | 23.0 | 3.33e-01 | 84.8% | 74.1% |
| 5e1qA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.58 | 26.0 | 3.48e-01 | 76.1% | 77.1% |
| 2qziA00 | 3.40.1720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Streptococcus thermophilus LMG 18311 protein like › Streptococcus thermophilus LMG 18311 protein like | 0.55 | 26.0 | 3.34e-01 | 84.2% | 76.2% |
| 2f0cA02 | 2.60.40.1830 | Mainly Beta › Sandwich › Immunoglobulin-like › Phage tail base-plate Siphoviridae RBP, head domain | 0.53 | 25.0 | 3.22e-01 | 89.7% | 76.0% |
| 3w9kA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.52 | 31.0 | 3.63e-01 | 81.5% | 80.7% |
| 1p32B00 | 3.10.280.10 | Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein | 0.52 | 31.0 | 3.25e-01 | 87.5% | 63.2% |
| 3dxpA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.51 | 26.0 | 3.48e-01 | 85.3% | 93.5% |
| 7zgmA01 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.50 | 42.0 | 3.88e-01 | 90.8% | 96.7% |
| 3kl0D01 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.50 | 28.0 | 3.58e-01 | 88.6% | 93.4% |
| 5e1qB01 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.50 | 42.0 | 3.70e-01 | 89.1% | 96.4% |
| 7jjtA01 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.50 | 25.0 | 3.32e-01 | 86.4% | 93.2% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 146301 | 527.1.1.3 ↗ | beta sandwiches › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › CrmD_SECRET | 0.78 | 64.0 | 6.85e-01 | 100.0% | 97.5% |
| 3399963 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.66 | 36.0 | 4.42e-01 | 82.1% | 81.7% |
| 4855718 | 527.1.1.1 ↗ | beta sandwiches › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › Orthopox_35kD | 0.64 | 60.0 | 5.90e-01 | 98.9% | 94.9% |
| 3957060 | 325.1.6.2 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Duplicated hybrid motif › Peptidase_M23 | 0.61 | 34.0 | 3.78e-01 | 90.2% | 67.6% |
| 3613138 | 12.6.1.1 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Glyco_hydro_65C | 0.60 | 21.0 | 3.36e-01 | 85.9% | 81.4% |
| 3283603 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.59 | 24.0 | 3.33e-01 | 99.5% | 75.3% |
| 4883226 | 5.1.3.21 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Fungal_lectin | 0.58 | 28.0 | 3.71e-01 | 72.3% | 84.9% |
| 4642258 | 12.1.1.24 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Malt_amylase_C | 0.58 | 21.0 | 3.13e-01 | 84.8% | 73.4% |
| 3707402 | 12.6.1.1 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Glyco_hydro_65C | 0.57 | 23.0 | 3.53e-01 | 87.0% | 90.7% |
| 4538358 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.56 | 26.0 | 3.24e-01 | 82.1% | 67.8% |
| 5036807 | 3111.1.1.0 ↗ | beta barrels › STT3/PglB/AglB beta-barrel domain › STT3/PglB/AglB beta-barrel domain › STT3/PglB/AglB beta-barrel domain | 0.55 | 29.0 | 3.83e-01 | 91.8% | 94.7% |
| 3265841 | 216.1.1.20 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › UBC_like | 0.55 | 28.0 | 3.75e-01 | 88.0% | 90.0% |
| 3962450 | 9.27.1.0 ↗ | beta barrels › Lipocalins/Streptavidin › LpqH › LpqH | 0.54 | 32.0 | 4.07e-01 | 97.3% | 100.0% |
| 5041090 | 11.1.1.103 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CARDB | 0.54 | 27.0 | 3.31e-01 | 83.2% | 72.2% |
| 3953943 | 9.27.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › LpqH › LpqH › Myco_19_kDa | 0.52 | 31.0 | 3.90e-01 | 97.8% | 97.3% |
| 4964630 | 331.3.1.11 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 | 0.52 | 34.0 | 3.85e-01 | 82.1% | 84.6% |
| 5012404 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.52 | 32.0 | 3.67e-01 | 85.3% | 83.8% |
| 3266952 | 12.3.1.46 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › ComC_SSD | 0.52 | 42.0 | 3.85e-01 | 84.8% | 98.8% |
| 5013018 | 274.1.1.0 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits | 0.52 | 32.0 | 3.67e-01 | 94.0% | 84.6% |
| 1498747 | 12.6.1.3 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Bac_rhamnosid_C | 0.51 | 24.0 | 3.35e-01 | 85.9% | 89.4% |
| 4021361 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.50 | 25.0 | 3.38e-01 | 85.9% | 94.4% |