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NODE_14_length_293356_cov_397-335986_prodigal-single.1__X__X__00280
Bact-VirNODE_14_length_293356_cov_397-335986_prodigal-single.1__X__X__00280
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 11-94_206-289
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1mpgA01 | 3.30.310.20 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › DNA-3-methyladenine glycosylase AlkA, N-terminal domain | 0.67 | 29.0 | 3.52e-01 | 98.8% | 58.9% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.65 | 26.0 | 3.27e-01 | 93.5% | 59.8% |
| 7p2yd01 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.62 | 31.0 | 4.01e-01 | 85.7% | 82.8% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.61 | 27.0 | 3.97e-01 | 72.6% | 93.2% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.58 | 26.0 | 3.56e-01 | 96.4% | 81.2% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 26.0 | 3.34e-01 | 94.0% | 75.3% |
| 2wssW01 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.55 | 29.0 | 3.74e-01 | 90.5% | 88.4% |
| 1odhA01 | 2.20.25.670 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › GCM domain, large subdomain | 0.55 | 24.0 | 3.45e-01 | 98.2% | 90.1% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.55 | 26.0 | 3.61e-01 | 72.6% | 87.4% |
| 6m9yA00 | 3.30.1300.40 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.55 | 17.0 | 2.89e-01 | 90.5% | 75.4% |
| 3lmlA01 | 3.10.450.690 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 32.0 | 3.72e-01 | 85.1% | 81.0% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 24.0 | 3.05e-01 | 89.3% | 71.4% |
| 2kr7A02 | 2.40.10.330 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.52 | 20.0 | 3.01e-01 | 100.0% | 89.5% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 28.0 | 3.15e-01 | 94.6% | 65.4% |
| 2xgtB01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.51 | 29.0 | 3.52e-01 | 91.7% | 88.1% |
| 1oqwA00 | 3.30.700.10 | Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin › Glycoprotein, Type 4 Pilin | 0.51 | 36.0 | 3.86e-01 | 91.7% | 83.3% |
| 1vwxg01 | 6.20.370.70 | Special › Other non-globular › Rhinovirus 14, subunit 4 › | 0.50 | 15.0 | 2.55e-01 | 95.8% | 94.6% |
| 2iecD00 | 3.30.1300.20 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 7,8-dihydroneopterin aldolase (MptD) | 0.50 | 33.0 | 3.83e-01 | 92.9% | 94.9% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4961800 | 2.21.1.0 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) | 0.76 | 59.0 | 6.42e-01 | 99.4% | 96.4% |
| 4961788 | 2.21.1.0 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) | 0.74 | 43.0 | 5.51e-01 | 100.0% | 96.0% |
| 5014572 | 2.21.1.3 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605 | 0.71 | 65.0 | 6.55e-01 | 99.4% | 97.0% |
| 5008625 | 632.12.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Vng1086c-like › Vng1086c-like › UPF0058 | 0.66 | 21.0 | 2.95e-01 | 92.9% | 56.5% |
| 4648665 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.65 | 24.0 | 3.36e-01 | 90.5% | 67.1% |
| 3221764 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.64 | 24.0 | 3.48e-01 | 94.0% | 72.5% |
| 3943353 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.62 | 28.0 | 3.80e-01 | 86.3% | 78.9% |
| 4386395 | 563.1.1.1 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP | 0.61 | 33.0 | 4.13e-01 | 88.1% | 86.0% |
| 5044962 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.61 | 25.0 | 3.28e-01 | 94.0% | 66.3% |
| 4976784 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.58 | 28.0 | 3.34e-01 | 94.0% | 67.3% |
| 4072975 | 2.1.1.57 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RecO_N | 0.57 | 28.0 | 3.84e-01 | 90.5% | 95.0% |
| 4082776 | 2.1.1.57 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RecO_N | 0.57 | 28.0 | 3.82e-01 | 90.5% | 95.0% |
| 3596144 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.57 | 28.0 | 4.03e-01 | 73.2% | 100.0% |
| 3229078 | 150.5.1.124 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › Claudin_3 | 0.56 | 28.0 | 3.73e-01 | 92.3% | 85.3% |
| 4105153 | 2.1.1.57 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RecO_N | 0.56 | 28.0 | 3.68e-01 | 89.9% | 90.6% |
| 3248470 | 3468.1.1.0 ↗ | a+b two layers › HLTF protein HIRAN domain › HLTF protein HIRAN domain › HLTF protein HIRAN domain | 0.56 | 37.0 | 4.24e-01 | 100.0% | 93.3% |
| 3883341 | 2.1.1.15 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon | 0.55 | 32.0 | 3.54e-01 | 92.3% | 70.4% |
| 4976409 | 283.1.1.0 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase | 0.54 | 34.0 | 4.12e-01 | 87.5% | 96.4% |
| 3961790 | 150.8.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE | 0.53 | 27.0 | 3.06e-01 | 92.9% | 62.3% |
| 4240811 | 2.1.1.57 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RecO_N | 0.53 | 27.0 | 3.64e-01 | 92.9% | 95.3% |
| 4034454 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.53 | 32.0 | 3.67e-01 | 90.5% | 80.8% |
| 4272096 | 2.1.1.57 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RecO_N | 0.53 | 28.0 | 3.65e-01 | 90.5% | 94.4% |
D2
medium
residues 123-205
Domain cluster:
representative
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3beyD00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.65 | 49.0 | 4.69e-01 | 92.8% | 69.1% |
| 3bulA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.63 | 44.0 | 4.35e-01 | 85.5% | 69.0% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 33.0 | 3.26e-01 | 86.7% | 47.3% |
| 3lpxA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.58 | 43.0 | 4.08e-01 | 79.5% | 93.2% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 41.0 | 3.38e-01 | 73.5% | 91.3% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 35.0 | 3.43e-01 | 89.2% | 55.6% |
| 4nqwB00 | 1.10.10.1320 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Anti-sigma factor, zinc-finger domain | 0.56 | 38.0 | 4.05e-01 | 88.0% | 80.8% |
| 2vixA02 | 1.10.150.630 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.56 | 36.0 | 3.53e-01 | 84.3% | 59.6% |
| 4j7zF00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.56 | 41.0 | 3.96e-01 | 78.3% | 69.1% |
| 2dpmA02 | 1.10.1020.10 | Mainly Alpha › Orthogonal Bundle › Adenine-specific Methyltransferase; domain 2 › Adenine-specific Methyltransferase, Domain 2 | 0.55 | 38.0 | 3.61e-01 | 73.5% | 100.0% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.55 | 43.0 | 3.34e-01 | 86.7% | 80.9% |
| 2c12A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.54 | 37.0 | 3.31e-01 | 73.5% | 66.1% |
| 4dyqA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.53 | 40.0 | 3.74e-01 | 89.2% | 64.1% |
| 5mmjo00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.53 | 31.0 | 3.22e-01 | 83.1% | 60.0% |
| 3pvlA03 | 1.20.80.10 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.53 | 40.0 | 3.65e-01 | 83.1% | 58.5% |
| 1p4wA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 38.0 | 3.83e-01 | 79.5% | 73.6% |
| 1gcvB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 35.0 | 3.06e-01 | 90.4% | 45.6% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3964536 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.67 | 43.0 | 4.14e-01 | 83.1% | 56.8% |
| 3606171 | 109.4.1.414 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MMS19_N | 0.66 | 48.0 | 3.29e-01 | 74.7% | 80.8% |
| 3210 | 173.1.1.1 ↗ | alpha arrays › Uteroglobin-like › Uteroglobin-like › Uteroglobin-like › Uteroglobin | 0.56 | 39.0 | 4.10e-01 | 72.3% | 92.9% |
| 2142296 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.56 | 33.0 | 3.14e-01 | 83.1% | 48.0% |
| 3164037 | 3405.1.1.6 ↗ | alpha duplicates or obligate multimers › FkpA dimerization domain-like › FkpA dimerization domain-like › FkpA dimerization domain-like › PF29764 | 0.56 | 40.0 | 3.51e-01 | 77.1% | 80.0% |
| 3570216 | 197.1.1.1 ↗ | alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › FERM_M | 0.56 | 41.0 | 3.73e-01 | 79.5% | 67.5% |
| 3995159 | 197.1.1.1 ↗ | alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › FERM_M | 0.55 | 43.0 | 3.90e-01 | 85.5% | 61.7% |
| 3481256 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.53 | 42.0 | 3.96e-01 | 89.2% | 80.0% |
| 4882409 | 568.1.1.0 ↗ | few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related | 0.53 | 36.0 | 3.37e-01 | 71.1% | 72.1% |
| None | — | 0.52 | 38.0 | 2.53e-01 | 77.1% | 55.9% |
D3
medium
residues 290-315_425-544
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07282.19 best | Cas12f1-like_TNB | 60.3 | 2.30e-16 | 44.5% | 88.3% |
CATH (2)
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5004517 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.84 | 59.0 | 5.07e-01 | 71.2% | 100.0% |
| 4007799 | 2484.1.1.211 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605, Cas12f1-like_TNB | 0.83 | 58.0 | 5.23e-01 | 71.2% | 100.0% |
| 5003640 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.82 | 58.0 | 5.11e-01 | 71.9% | 98.0% |
| 5005258 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.81 | 58.0 | 5.02e-01 | 72.6% | 100.0% |
| 4961847 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.80 | 56.0 | 4.78e-01 | 70.5% | 92.1% |
| 4946534 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.80 | 58.0 | 4.64e-01 | 73.3% | 96.9% |
| 4941648 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.80 | 56.0 | 5.02e-01 | 71.9% | 100.0% |
| 4979556 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.79 | 56.0 | 4.85e-01 | 72.6% | 100.0% |
| 5011867 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.77 | 53.0 | 5.05e-01 | 70.5% | 99.4% |
| 5000042 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.77 | 55.0 | 4.80e-01 | 73.3% | 98.5% |
| 5051266 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.74 | 52.0 | 4.43e-01 | 71.9% | 89.3% |
| 3603682 | 2484.1.1.211 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605, Cas12f1-like_TNB | 0.73 | 51.0 | 4.34e-01 | 71.2% | 84.4% |
| 4992438 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.71 | 58.0 | 5.58e-01 | 84.9% | 98.2% |
| 5011615 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.70 | 58.0 | 5.04e-01 | 86.3% | 87.6% |
| 4943069 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.68 | 48.0 | 4.92e-01 | 71.9% | 86.4% |
| 4994780 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.66 | 56.0 | 4.78e-01 | 87.0% | 94.4% |
| 4933788 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.66 | 56.0 | 4.87e-01 | 88.4% | 100.0% |
| 5044642 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.64 | 54.0 | 4.39e-01 | 87.7% | 97.6% |
| 4972401 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.63 | 52.0 | 4.48e-01 | 85.6% | 90.2% |
| 4934130 | 2484.1.1.139 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF429 | 0.61 | 44.0 | 3.92e-01 | 72.6% | 95.5% |
| 5024287 | 103.5.1.11 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like › DUF2067 | 0.61 | 33.0 | 4.34e-01 | 88.4% | 100.0% |
| 5013223 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.61 | 50.0 | 4.40e-01 | 85.6% | 95.6% |
| 5055179 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.61 | 54.0 | 4.64e-01 | 91.8% | 99.0% |
| 5075524 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.58 | 48.0 | 4.34e-01 | 87.0% | 96.9% |
| 4982982 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.57 | 47.0 | 4.22e-01 | 86.3% | 98.5% |
| 4483341 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.55 | 26.0 | 2.91e-01 | 89.0% | 54.8% |
| 5042592 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.52 | 42.0 | 3.81e-01 | 83.6% | 100.0% |
D4
medium
residues 316-424
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5mmjo00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.69 | 43.0 | 5.11e-01 | 97.2% | 92.0% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 51.0 | 5.23e-01 | 93.6% | 84.8% |
| 3t5vA00 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 50.0 | 3.57e-01 | 86.2% | 82.6% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 51.0 | 4.04e-01 | 88.1% | 80.6% |
| 1xeqB00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.60 | 39.0 | 4.37e-01 | 80.7% | 84.7% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 47.0 | 4.85e-01 | 94.5% | 87.3% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 53.0 | 4.14e-01 | 96.3% | 85.6% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 43.0 | 4.49e-01 | 89.9% | 82.4% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.58 | 52.0 | 4.27e-01 | 97.2% | 98.5% |
| 7odyC01 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.57 | 36.0 | 3.88e-01 | 85.3% | 73.9% |
| 4hkaA01 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 51.0 | 3.72e-01 | 99.1% | 70.4% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 51.0 | 4.20e-01 | 97.2% | 87.9% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 43.0 | 4.09e-01 | 92.7% | 74.6% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.52 | 43.0 | 3.94e-01 | 89.9% | 82.8% |
| 3r2qA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 41.0 | 4.07e-01 | 97.2% | 81.4% |
| 3geeA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.51 | 44.0 | 3.88e-01 | 96.3% | 82.1% |
| 4hteA03 | 1.10.167.30 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › | 0.51 | 36.0 | 4.15e-01 | 85.3% | 100.0% |
| 7tj9A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.51 | 43.0 | 4.41e-01 | 94.5% | 92.5% |
ECOD (42)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3573801 | 604.1.1.3 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › MAP65_ASE1 | 0.66 | 48.0 | 4.65e-01 | 75.2% | 80.8% |
| 3992995 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.66 | 45.0 | 4.69e-01 | 97.2% | 74.8% |
| 3455464 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.66 | 55.0 | 4.91e-01 | 90.8% | 74.2% |
| 3194153 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.64 | 48.0 | 5.18e-01 | 94.5% | 89.5% |
| 3471023 | 164.1.1.15 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › PPPI_inhib | 0.64 | 56.0 | 4.97e-01 | 97.2% | 84.4% |
| 3596950 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.64 | 51.0 | 4.10e-01 | 85.3% | 81.9% |
| 3735947 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 52.0 | 4.02e-01 | 86.2% | 92.5% |
| 3963952 | 3684.1.1.26 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › SirB | 0.62 | 52.0 | 5.02e-01 | 89.0% | 87.1% |
| 3827181 | 601.51.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin | 0.62 | 55.0 | 4.02e-01 | 95.4% | 62.8% |
| 3789156 | 192.29.1.223 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Syntaxin_2 | 0.61 | 51.0 | 4.33e-01 | 87.2% | 90.6% |
| 3650099 | 5001.1.1.173 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF4220 | 0.61 | 48.0 | 3.69e-01 | 83.5% | 95.9% |
| 3465829 | 109.3.1.31 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF4220 | 0.60 | 49.0 | 3.71e-01 | 86.2% | 83.9% |
| 3500031 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 47.0 | 4.97e-01 | 89.0% | 90.0% |
| 3171689 | 603.1.1.105 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 | 0.60 | 52.0 | 5.04e-01 | 91.7% | 83.3% |
| 4013947 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.59 | 50.0 | 3.81e-01 | 89.0% | 78.8% |
| 3924665 | 604.1.1.136 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_7 | 0.59 | 48.0 | 4.89e-01 | 91.7% | 86.7% |
| 3736924 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.59 | 50.0 | 4.63e-01 | 91.7% | 80.0% |
| 3464741 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.58 | 47.0 | 3.75e-01 | 85.3% | 47.1% |
| 3497641 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.58 | 45.0 | 4.75e-01 | 89.9% | 90.0% |
| 3221932 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 47.0 | 4.78e-01 | 86.2% | 89.5% |
| 3857880 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.57 | 48.0 | 4.39e-01 | 94.5% | 68.3% |
| 4932124 | 5069.1.1.2 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ni_hydr_CYTB | 0.57 | 47.0 | 3.55e-01 | 86.2% | 77.1% |
| 3654456 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.57 | 49.0 | 3.64e-01 | 97.2% | 99.7% |
| 3669425 | 109.4.1.541 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4220 | 0.57 | 53.0 | 3.97e-01 | 100.0% | 69.6% |
| 3884746 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 48.0 | 4.46e-01 | 94.5% | 73.3% |
| 4878251 | 601.7.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › NTase_sub_bind | 0.56 | 49.0 | 4.60e-01 | 93.6% | 91.0% |
| 3713159 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.56 | 43.0 | 4.24e-01 | 91.7% | 74.2% |
| 3940777 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 45.0 | 4.60e-01 | 92.7% | 89.5% |
| 3894911 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 45.0 | 4.49e-01 | 93.6% | 84.5% |
| 5052572 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.55 | 50.0 | 4.41e-01 | 100.0% | 88.6% |
| 3516461 | 603.1.1.103 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF29732 | 0.55 | 41.0 | 4.17e-01 | 91.7% | 78.2% |
| 4025790 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.55 | 49.0 | 4.54e-01 | 95.4% | 78.5% |
| 3704359 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.55 | 43.0 | 3.67e-01 | 91.7% | 51.4% |
| 4053331 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.55 | 47.0 | 3.47e-01 | 95.4% | 95.7% |
| 2774800 | 1114.1.1.0 ↗ | alpha arrays › Serine acetyltransferase N-terminal domain › Serine acetyltransferase N-terminal domain › Serine acetyltransferase N-terminal domain | 0.54 | 46.0 | 3.85e-01 | 96.3% | 69.2% |
| 3459951 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.54 | 47.0 | 4.69e-01 | 92.7% | 97.3% |
| 4977102 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.53 | 46.0 | 4.45e-01 | 94.5% | 97.6% |
| 3642682 | 603.1.1.5 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N | 0.53 | 46.0 | 4.59e-01 | 94.5% | 93.0% |
| 3585439 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.53 | 40.0 | 3.05e-01 | 98.2% | 34.4% |
| 3640330 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 46.0 | 4.29e-01 | 98.2% | 85.7% |
| 3565766 | 603.1.1.103 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF29732 | 0.52 | 46.0 | 4.08e-01 | 97.2% | 82.5% |
| 5032080 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.50 | 40.0 | 4.01e-01 | 87.2% | 86.1% |