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NS1

Euk-Vir

Umatilla_virus

NS1__YP_009047261__Umatilla_virus__40060

Identity

Accession:: YP_009047261 ↗
Protein ID:: NS1
Kingdom:: euk

Quality

76.4 mean pLDDT

Taxonomy

Orthornavirae› Duplornaviricota› Resentoviricetes› Reovirales› Sedoreoviridae› Orbivirus› Umatilla_virus

TaxID: 40060

Cluster

View cluster (12 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-96

PDB

Domain cluster: rep: tubule_protein__YP_009158886__Wad_Medani_virus__40067__D1-96

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01718.24 best	Orbi_NS1	98.2	5.40e-28	100.0%	17.2%

D2 high residues 147-272

PDB

Domain cluster: rep: tubule_protein__YP_009163941__Fengkai_orbivirus__1692107__D132-252

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01718.24 best	Orbi_NS1	121.2	6.00e-35	100.0%	24.6%

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1tm0A02	3.10.310.10	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1	0.52	36.0	3.50e-01	72.2%	89.7%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3476436	327.5.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins	0.53	37.0	3.62e-01	73.0%	75.0%
4995790	246.2.1.0 ↗	a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases	0.51	35.0	2.77e-01	71.4%	92.1%

D3 medium residues 97-140_471-514

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01718.24 best	Orbi_NS1	29.6	3.40e-07	61.4%	9.2%

CATH (6)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4ie5A02	1.20.58.1470	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FTO C-terminal domain	0.70	35.0	3.05e-01	95.5%	31.3%
1m62A00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.68	34.0	3.47e-01	100.0%	49.4%
1wj5A01	1.10.10.980	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › CST, Suppressor of Cdc13 homolog, complex subunit STN1, N-terminal domain	0.55	33.0	3.23e-01	80.7%	52.0%
3gi8C00	1.20.1740.10	Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I	0.54	47.0	3.08e-01	100.0%	80.5%
2gmyD00	1.20.1290.10	Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like	0.51	45.0	3.83e-01	100.0%	80.0%
1ji8A02	1.10.10.370	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DsrC protein, C-terminal domain	0.51	28.0	3.11e-01	89.8%	68.8%

ECOD (9)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4610814	185.1.1.1 ↗	alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › Tryp_alpha_amyl	0.59	44.0	4.07e-01	80.7%	91.3%
3962986	4033.1.1.0 ↗	alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like	0.56	32.0	3.08e-01	100.0%	46.7%
4984506	601.7.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain	0.56	41.0	3.67e-01	98.9%	54.5%
3706130	142.1.1.0 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors	0.56	36.0	3.60e-01	85.2%	61.1%
3610875	101.1.10.0 ↗	alpha arrays › HTH › HTH › Cyclin-like	0.56	39.0	3.52e-01	86.4%	52.0%
3737311	192.2.1.17 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Sin3_corepress	0.54	31.0	2.74e-01	100.0%	38.5%
3906127	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.52	30.0	2.77e-01	100.0%	42.6%
3253186	633.6.1.8 ↗	alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX_C_alpha1	0.50	38.0	2.89e-01	79.5%	63.4%
3746763	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.50	35.0	3.01e-01	100.0%	48.5%

D4 medium residues 273-359

PDB

Domain cluster: rep: Nsp1__YP_008719915__Mobuck_virus__1408137__D271-338

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01718.24 best	Orbi_NS1	52.8	3.20e-14	100.0%	15.5%

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5jazA03	1.10.1740.10	Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif	0.57	43.0	4.25e-01	80.5%	96.7%

D5 medium residues 360-470_515-530

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01718.24 best	Orbi_NS1	117.2	9.90e-34	92.9%	21.9%

CATH (26)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3k8pC02	1.10.357.150	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 ›	0.63	48.0	4.19e-01	80.3%	64.7%
3ly7A02	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.62	37.0	3.49e-01	86.6%	46.6%
2a9uA01	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.59	44.0	4.47e-01	98.4%	78.6%
4wp3C00	3.30.70.1230	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain	0.58	42.0	3.69e-01	74.0%	92.0%
2a0uB01	1.20.120.420	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1	0.58	46.0	4.27e-01	84.3%	86.9%
1wfdA00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.57	35.0	3.98e-01	100.0%	82.8%
2nrlA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.57	41.0	3.95e-01	74.8%	77.9%
6gpxB00	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.57	44.0	3.56e-01	84.3%	85.6%
2wzkA02	1.20.1310.10	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats	0.56	42.0	4.21e-01	77.2%	89.8%
4g1tA03	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.56	42.0	3.37e-01	77.2%	49.6%
1cg5B00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.55	40.0	3.89e-01	74.8%	80.9%
6uqjA02	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.55	44.0	3.25e-01	85.0%	81.7%
3fnbA01	1.20.1440.110	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase	0.55	42.0	4.39e-01	78.7%	87.7%
1j1jA02	1.20.58.200	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2	0.55	35.0	4.14e-01	72.4%	95.3%
1fpoC02	1.20.1280.20	Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain	0.55	35.0	4.13e-01	93.7%	91.2%
7sk7A01	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.54	42.0	3.42e-01	83.5%	85.8%
2n3eA01	1.10.274.70	Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain	0.54	39.0	4.06e-01	74.8%	88.7%
3tm8B00	1.10.3210.10	Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432	0.53	43.0	3.31e-01	88.2%	98.0%
4abnA01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.53	44.0	3.35e-01	87.4%	49.1%
1vw4F02	3.90.930.12	Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6	0.53	31.0	3.50e-01	100.0%	78.3%
3ug9A02	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.52	39.0	3.31e-01	80.3%	85.3%
6ljaA01	1.50.10.100	Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase	0.52	42.0	3.09e-01	87.4%	64.2%
1uurA01	1.20.58.240	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1	0.51	37.0	3.92e-01	73.2%	96.4%
1vctA01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.51	36.0	3.92e-01	73.2%	88.1%
2wauA01	1.20.1310.20	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain	0.51	41.0	3.91e-01	87.4%	100.0%
3fflA00	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.51	39.0	3.97e-01	89.0%	81.7%

ECOD (31)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3596608	1134.1.1.0 ↗	alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain	0.73	39.0	4.67e-01	82.7%	77.6%
4937394	633.12.1.1 ↗	alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147	0.68	37.0	4.45e-01	85.0%	81.2%
3720004	604.3.1.0 ↗	alpha bundles › Spectrin repeat-like › BAG domain › BAG domain	0.67	40.0	4.90e-01	71.7%	89.4%
3968965	604.3.1.0 ↗	alpha bundles › Spectrin repeat-like › BAG domain › BAG domain	0.63	36.0	4.23e-01	80.3%	78.9%
3586649	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.61	48.0	4.00e-01	83.5%	55.5%
2814210	109.4.1.1427 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6, TPR_8, TPR_19	0.59	36.0	4.39e-01	83.5%	100.0%
3247756	106.1.1.1 ↗	alpha arrays › Globin-like › Globin-like › Globin-like › Globin	0.58	42.0	3.79e-01	74.8%	72.0%
3390061	5063.1.1.22 ↗	alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › LIN9_C	0.58	40.0	4.26e-01	70.1%	81.8%
5061464	2006.1.2.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH	0.57	45.0	4.02e-01	84.3%	91.4%
3941077	106.1.1.0 ↗	alpha arrays › Globin-like › Globin-like › Globin-like	0.57	41.0	4.01e-01	74.8%	80.0%
3693073	604.12.1.0 ↗	alpha bundles › Spectrin repeat-like › MIT domain › MIT domain	0.56	37.0	4.22e-01	88.2%	89.5%
4948515	2006.1.2.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH	0.56	44.0	3.89e-01	83.5%	94.7%
3901233	5001.1.1.1 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1	0.56	43.0	3.38e-01	80.3%	85.8%
3306315	109.4.1.189 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2	0.56	39.0	4.36e-01	79.5%	95.8%
4460268	310.2.1.1 ↗	a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF	0.56	40.0	3.47e-01	74.8%	91.1%
3789118	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.54	44.0	3.99e-01	86.6%	78.9%
3748911	5001.1.1.1 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1	0.54	42.0	3.08e-01	82.7%	61.1%
3208696	109.4.1.2122 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Zw10_middle, ZW10_C2	0.54	46.0	2.96e-01	92.9%	32.6%
4564281	109.4.1.1253 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Atp25_C	0.53	44.0	3.27e-01	89.8%	34.7%
3837429	109.4.1.585 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF627	0.53	45.0	3.50e-01	90.6%	95.8%
4976199	2006.1.2.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH	0.53	45.0	3.80e-01	92.9%	98.1%
4954843	604.5.1.2 ↗	alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU	0.52	37.0	4.16e-01	72.4%	97.9%
3735509	109.4.1.356 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans	0.52	43.0	2.93e-01	91.3%	46.5%
3743298	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.52	39.0	3.72e-01	78.7%	69.3%
4014527	532.2.1.0 ↗	alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains	0.52	34.0	3.90e-01	74.0%	89.5%
4940312	2006.1.2.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH	0.52	45.0	3.92e-01	93.7%	100.0%
3239827	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.51	43.0	3.68e-01	92.1%	86.7%
3595701	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.51	42.0	3.98e-01	89.8%	92.2%
5075796	2006.1.2.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH	0.51	44.0	3.77e-01	95.3%	98.0%
5017296	2006.1.2.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH	0.51	44.0	3.81e-01	95.3%	99.0%
5036847	2006.1.2.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH	0.51	43.0	3.78e-01	93.7%	99.5%