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NS1

Euk-Vir

Sesavirus_CSL10538

NS1__YP_009116876__Sesavirus_CSL10538__1519097

Identity

Accession:
YP_009116876 ↗
Protein ID:
NS1
Kingdom:
euk

Quality

71.0 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Quintoviricetes› Piccovirales› Parvoviridae› Sesavirus_CSL10538

TaxID: 1519097

Cluster

View cluster (29 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 12-170
PDB
D2 medium residues 201-253
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u0jA01 1.10.10.950 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.81 70.0 6.99e-01 96.2% 92.7%
2gxaE01 1.10.10.510 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain 0.71 66.0 5.87e-01 100.0% 80.8%
1n5uA02 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.70 45.0 3.78e-01 81.1% 37.8%
1ltlA01 3.30.1640.10 Alpha Beta › 2-Layer Sandwich › mini-chromosome maintenance (MCM) complex, chain A, domain 1 › mini-chromosome maintenance (MCM) complex, chain A, domain 1 0.70 61.0 5.13e-01 100.0% 80.0%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.67 52.0 4.21e-01 100.0% 42.7%
2rreA00 1.10.10.2010 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.65 56.0 5.10e-01 100.0% 86.5%
1he8A03 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.65 54.0 4.23e-01 98.1% 44.1%
3h20A04 1.10.1240.50 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.64 56.0 4.79e-01 100.0% 64.0%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.64 56.0 4.85e-01 98.1% 74.7%
6e6qA00 1.10.10.1100 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › BFD-like [2Fe-2S]-binding domain 0.64 54.0 5.34e-01 100.0% 100.0%
5bu9A00 3.20.20.300 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycoside hydrolase, family 3, N-terminal domain 0.62 56.0 3.38e-01 100.0% 25.7%
2oyyA00 6.10.80.10 Special › Helix non-globular › DNA polymerase; domain 1 › Hexameric tyrosine-coordinated heme protein (HTHP) 0.61 42.0 3.87e-01 73.6% 67.6%
1mswD04 1.10.287.280 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 42.0 3.91e-01 100.0% 56.4%
5oklA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.57 44.0 3.66e-01 86.8% 50.5%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.57 42.0 3.67e-01 81.1% 51.2%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 50.0 4.52e-01 100.0% 83.6%
4kwaB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 47.0 3.31e-01 100.0% 51.0%
7ep1B01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.55 47.0 3.12e-01 100.0% 22.3%
4aciA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 44.0 3.25e-01 100.0% 48.9%
2vl7A02 1.10.275.30 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › 0.54 43.0 3.40e-01 86.8% 93.6%
3ddhA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.53 42.0 3.75e-01 90.6% 95.1%
2ia0A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 39.0 3.95e-01 96.2% 85.2%
1bhaA00 1.10.287.170 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 39.0 3.62e-01 83.0% 86.6%
2cu7A01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.50 39.0 4.06e-01 94.3% 94.0%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4995204 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.69 45.0 4.06e-01 75.5% 51.4%
4940562 179.1.1.0 ↗ alpha bundles › CO dehydrogenase ISP C-domain like › CO dehydrogenase ISP C-domain like › CO dehydrogenase ISP C-domain like 0.68 57.0 5.56e-01 94.3% 86.7%
5003639 2.21.1.0 ↗ beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) 0.68 59.0 4.28e-01 100.0% 35.5%
5009771 2.21.1.5 ↗ beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › PF27234 0.67 59.0 4.15e-01 100.0% 33.5%
5016721 6132.1.1.14 ↗ alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › PF29261 0.65 59.0 5.68e-01 100.0% 93.3%
4974313 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.64 48.0 4.80e-01 83.0% 78.2%
5080157 7000.1.1.0 ↗ alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS 0.60 51.0 4.76e-01 100.0% 82.9%
5040698 7000.1.1.0 ↗ alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS 0.59 50.0 4.84e-01 100.0% 88.3%
4243573 184.1.1.1 ↗ alpha arrays › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Nucleoside phosphorylase/phosphoribosyltransferase-N › Glycos_trans_3N 0.56 46.0 4.39e-01 96.2% 78.5%
2628027 101.1.11.90 ↗ alpha arrays › HTH › HTH › Ribbon-helix-helix › DotY 0.56 48.0 4.39e-01 100.0% 74.0%
3868871 213.1.1.1 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.55 48.0 3.26e-01 100.0% 72.7%
4015104 3932.1.1.0 ↗ alpha bundles › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain 0.55 42.0 3.99e-01 100.0% 69.2%
5005176 604.15.1.0 ↗ alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like 0.55 44.0 4.18e-01 92.5% 83.1%
3598908 192.4.1.0 ↗ alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) 0.53 47.0 4.51e-01 100.0% 91.7%
3216704 102.1.1.77 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › TNK-like_SAM 0.53 43.0 4.04e-01 100.0% 73.8%
3489866 210.1.2.0 ↗ a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain 0.51 44.0 4.23e-01 100.0% 92.1%
D3 medium residues 254-379_444-463
PDB
Domain cluster: rep: Rep_78_protein__YP_680423__adeno-associated_virus_2__10804__D308-421_457-489
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF01057.24 best Parvo_NS1 129.9 1.30e-37 91.1% 39.1%
PF00519.24 PPV_E1_C 35.4 9.70e-09 76.0% 30.1%
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u0jA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.86 82.0 7.16e-01 99.3% 94.7%
1tueD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.76 71.0 6.31e-01 99.3% 99.5%
1z1vA00 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.64 27.0 3.79e-01 85.6% 81.4%
2f2cA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.55 26.0 3.05e-01 87.0% 59.4%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4880005 10.2.1.16 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Parvo_NS1 0.87 61.0 5.92e-01 74.7% 65.8%
2704206 2004.1.1.57 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Parvo_NS1 0.83 78.0 6.18e-01 100.0% 74.3%
3474509 2004.1.1.57 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Parvo_NS1 0.80 65.0 6.15e-01 84.2% 72.9%
3479645 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.80 65.0 5.99e-01 84.2% 68.9%
9753 2004.1.1.48 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PPV_E1_C 0.77 72.0 6.38e-01 99.3% 99.5%
4965519 2004.1.1.194 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2 0.51 37.0 3.33e-01 74.7% 88.1%