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NS1

Euk-Vir

Cutavirus

NS1__YP_009508804__Cutavirus__1867125

Identity

Accession:: YP_009508804 ↗
Protein ID:: NS1
Kingdom:: euk

Quality

81.9 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Quintoviricetes› Piccovirales› Parvoviridae› Protoparvovirus› Cutavirus

TaxID: 1867125

Cluster

View cluster (29 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-26_194-263

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF12433.15 best	PV_NSP1	51.1	2.00e-13	69.8%	78.0%

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5ljmA00	1.20.58.2190	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.53	47.0	3.71e-01	100.0%	75.9%
3gudA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.51	31.0	2.95e-01	92.7%	48.7%

ECOD (7)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4980882	304.4.1.0 ↗	a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel	0.58	30.0	3.08e-01	97.9%	48.9%
3414027	3226.1.1.3 ↗	alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › HCO3_cotransp	0.56	46.0	2.88e-01	88.5%	63.1%
4978746	5059.1.1.1 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA	0.55	48.0	3.43e-01	97.9%	93.7%
3709611	5073.1.1.7 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › PhoLip_ATPase_C	0.55	44.0	2.94e-01	100.0%	22.1%
3786023	101.1.2.154 ↗	alpha arrays › HTH › HTH › winged helix domain › CDT1_C	0.54	37.0	2.80e-01	100.0%	27.9%
3595144	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.54	43.0	2.75e-01	100.0%	16.8%
3595242	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.52	35.0	3.76e-01	100.0%	83.7%

D2 medium residues 27-193

PDB

Domain cluster: rep: NS1__YP_009552695__Rhinolophus_pusillus_bocaparvovirus_1__2053079__D4-183

D3 medium residues 288-370

PDB

Domain cluster: rep: Rep_68_protein__YP_680422__adeno-associated_virus_2__10804__D219-282

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01057.24 best	Parvo_NS1	35.4	8.40e-09	100.0%	29.9%

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3pubA01	1.10.10.2400	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Lepidopteran low molecular weight (30 kD) lipoprotein, N-terminal domain	0.69	41.0	4.28e-01	72.3%	64.9%
3ay8A02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.57	41.0	3.47e-01	74.7%	86.0%
4unfA02	1.10.340.30	Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Hypothetical protein; domain 2	0.55	38.0	3.41e-01	71.1%	60.7%
6wh0A01	1.10.437.10	Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like	0.55	43.0	3.56e-01	84.3%	53.3%
4gr2A00	1.10.1200.210	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Chaperonin-like RbcX	0.50	39.0	3.57e-01	83.1%	80.0%

ECOD (11)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4880005	10.2.1.16 ↗	beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Parvo_NS1	0.77	70.0	5.55e-01	97.6%	71.5%
4969516	101.1.15.0 ↗	alpha arrays › HTH › HTH › HAT1, C-terminal domain	0.64	44.0	5.06e-01	73.5%	100.0%
4001540	2007.1.2.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I	0.64	44.0	3.39e-01	72.3%	78.0%
4955688	2.21.1.5 ↗	beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › PF27234	0.62	44.0	3.56e-01	74.7%	38.8%
3785424	5069.1.3.6 ↗	alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › MCP1_TM	0.61	43.0	3.05e-01	78.3%	23.9%
4935262	101.8.1.2 ↗	alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2	0.60	48.0	3.88e-01	86.7%	45.0%
3740294	3826.1.1.0 ↗	alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR)	0.60	45.0	3.73e-01	80.7%	46.7%
4026018	6026.1.1.1 ↗	alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21	0.59	41.0	3.64e-01	71.1%	60.9%
2628027	101.1.11.90 ↗	alpha arrays › HTH › HTH › Ribbon-helix-helix › DotY	0.58	40.0	4.25e-01	74.7%	82.2%
4970801	101.1.4.3 ↗	alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_3	0.54	37.0	3.73e-01	92.8%	69.4%
3437032	4085.1.1.1 ↗	alpha arrays › RbcX-like › RbcX-like › RbcX-like › RbcX	0.51	39.0	3.50e-01	83.1%	70.8%

D4 medium residues 371-391_526-564

PDB

Domain cluster: representative

CATH (7)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3bz6A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	44.0	3.89e-01	83.3%	94.4%
2zt5A02	3.30.40.230	Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 ›	0.55	33.0	2.99e-01	90.0%	41.7%
3onjA00	1.20.58.400	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins	0.52	35.0	3.03e-01	70.0%	86.6%
3sllA02	1.10.12.10	Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2	0.52	38.0	3.85e-01	80.0%	93.4%
2pbiA02	1.10.1240.60	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 ›	0.51	41.0	3.65e-01	98.3%	87.1%
4fcyB02	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.51	37.0	3.65e-01	98.3%	72.3%
1anxA04	1.10.220.10	Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin	0.50	33.0	3.20e-01	70.0%	66.7%

ECOD (6)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3686779	2485.1.1.0 ↗	a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like	0.55	42.0	2.85e-01	83.3%	55.7%
59126	109.1.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C	0.55	40.0	3.19e-01	78.3%	89.0%
5077192	3352.1.1.25 ↗	alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PIG-U	0.54	47.0	2.98e-01	98.3%	77.3%
4993180	183.1.1.1 ↗	alpha duplicates or obligate multimers › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain › Fe_dep_repr_C	0.54	44.0	3.54e-01	95.0%	73.8%
3689499	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.51	42.0	2.82e-01	98.3%	93.8%
1108191	604.17.1.1 ↗	alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like › DUF447_C	0.51	34.0	3.35e-01	70.0%	80.6%

D5 medium residues 392-525

PDB

Domain cluster: rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764

Pfam (3)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01057.24 best	Parvo_NS1	170.4	5.50e-50	100.0%	49.1%
PF00519.24	PPV_E1_C	44.1	2.10e-11	97.8%	36.0%
PF19263.6	DUF5906	40.1	7.40e-10	80.6%	92.0%