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NS1

Euk-Vir

Rhinolophus_pusillus_bocaparvovirus_2

NS1__YP_009553047__Rhinolophus_pusillus_bocaparvovirus_2__2053080

Identity

Accession:
YP_009553047 ↗
Protein ID:
NS1
Kingdom:
euk

Quality

72.7 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Quintoviricetes› Piccovirales› Parvoviridae› Bocaparvovirus› Rhinolophus_pusillus_bocaparvovirus_2

TaxID: 2053080

Cluster

View cluster (44 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 234-291
PDB
Domain cluster: rep: non-structural_protein_1__YP_009272913__Mink_bocavirus_1__2259808__D352-409
D2 high residues 311-503
PDB
Domain cluster: rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF01057.24 best Parvo_NS1 231.5 1.30e-68 95.9% 65.3%
PF00519.24 PPV_E1_C 28.4 1.30e-06 82.9% 38.1%
D3 medium residues 1-52
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF22419.3 best HBoV_NS1-like_N 32.2 9.60e-08 100.0% 19.5%
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4kw3A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.95 89.0 5.41e-01 100.0% 19.5%
2ql8A00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.79 69.0 5.04e-01 100.0% 46.4%
1lqlA02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.68 58.0 4.75e-01 100.0% 57.3%
2pn2A00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.67 55.0 4.17e-01 98.1% 65.0%
6f1uK02 3.90.1150.210 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit 0.66 57.0 4.20e-01 100.0% 83.4%
4akrA02 3.90.1150.210 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit 0.66 56.0 4.15e-01 100.0% 84.4%
4k3cA01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.62 49.0 4.37e-01 92.3% 58.5%
2mq8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.61 52.0 4.12e-01 100.0% 73.2%
1qlmA02 3.30.1030.10 Alpha Beta › 2-Layer Sandwich › Methenyltetrahydromethanopterin Cyclohydrolase; Chain A, domain 2 › Methenyltetrahydromethanopterin Cyclohydrolase; Chain A, domain 2 0.60 49.0 3.46e-01 100.0% 39.9%
1bdfA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.60 49.0 4.09e-01 100.0% 53.8%
1ti2B01 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 44.0 3.41e-01 84.6% 64.7%
3hm2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 46.0 3.36e-01 92.3% 98.8%
2l2nA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.59 41.0 3.79e-01 75.0% 95.8%
6gdxA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 49.0 3.99e-01 98.1% 50.5%
2n3gA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.59 44.0 4.06e-01 84.6% 97.2%
1whqA01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.58 42.0 3.87e-01 78.8% 95.8%
4fvmA02 3.30.70.2820 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 47.0 3.95e-01 100.0% 56.3%
1j2vA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 48.0 4.01e-01 100.0% 53.5%
3cygA01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.57 46.0 3.66e-01 96.2% 79.8%
3e0jB00 3.90.1030.20 Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain 0.56 38.0 2.88e-01 73.1% 44.8%
2v73A00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.55 36.0 2.51e-01 90.4% 19.1%
3ms6A00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.55 37.0 3.15e-01 84.6% 41.1%
3p9aF00 1.10.132.80 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.55 42.0 3.09e-01 82.7% 38.8%
2vpzB01 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 42.0 3.30e-01 92.3% 57.8%
4pkcC00 6.20.90.20 Special › Other non-globular › SH3 type barrels. › Benzylsuccinate synthase gamma subunit 0.55 38.0 4.05e-01 84.6% 92.7%
2qrdB01 2.20.25.290 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.54 36.0 4.06e-01 88.5% 94.6%
2abyA00 3.30.70.1980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Uncharacterised protein PF09406, DUF2004 0.54 42.0 3.32e-01 90.4% 46.7%
2i0oA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.54 45.0 2.83e-01 94.2% 39.7%
4noiA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.54 41.0 3.57e-01 98.1% 55.3%
2znhA03 6.20.40.10 Special › Other non-globular › Porin MspA ribbon fold › 0.54 37.0 3.91e-01 75.0% 93.6%
4rx6D00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 44.0 3.61e-01 98.1% 50.5%
2qlvB02 2.20.25.290 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.53 37.0 4.06e-01 88.5% 97.4%
2hv2A01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.53 43.0 3.66e-01 98.1% 55.8%
6vfrA01 2.60.40.60 Mainly Beta › Sandwich › Immunoglobulin-like › Cadherins 0.53 42.0 3.49e-01 96.2% 83.8%
6kd0A01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 37.0 2.34e-01 76.9% 87.0%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.52 41.0 3.40e-01 100.0% 44.1%
4lgvD02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.52 40.0 2.77e-01 100.0% 41.9%
2a22B00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.52 42.0 2.88e-01 94.2% 30.0%
1p1lA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 37.0 3.05e-01 76.9% 40.2%
5cm2Z00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 41.0 2.84e-01 92.3% 33.2%
4c89C00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.50 40.0 2.41e-01 84.6% 26.0%
6m9yA00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.50 39.0 3.84e-01 100.0% 84.2%
1cx8A01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.50 43.0 2.73e-01 100.0% 21.5%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1168216 304.55.1.11 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › HBoV_NS1-like_N 0.95 89.0 6.05e-01 100.0% 33.1%
4954522 878.1.1.1 ↗ a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.78 68.0 5.64e-01 100.0% 61.7%
4183868 878.1.1.1 ↗ a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.72 57.0 5.06e-01 100.0% 59.5%
4564327 878.1.1.1 ↗ a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.71 57.0 4.98e-01 98.1% 57.8%
4899007 3121.1.1.0 ↗ a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.68 54.0 4.92e-01 90.4% 65.3%
3255418 2011.1.1.8 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 0.64 50.0 3.02e-01 88.5% 54.5%
4991352 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.64 47.0 2.96e-01 90.4% 14.7%
5050683 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.63 40.0 3.07e-01 88.5% 26.4%
4998648 4312.1.1.0 ↗ a+b two layers › RelE-like › RelE-like › RelE-like 0.62 43.0 3.54e-01 82.7% 40.0%
5878 324.1.1.1 ↗ a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.62 50.0 3.92e-01 100.0% 43.9%
3687618 304.9.1.79 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF28976 0.59 49.0 3.57e-01 98.1% 43.6%
3583548 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 51.0 4.48e-01 100.0% 93.8%
3707891 243.3.1.73 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › DUF7920 0.59 51.0 4.28e-01 100.0% 95.6%
3204836 2492.1.1.32 ↗ a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › OTT_1508_deam 0.59 46.0 3.42e-01 94.2% 31.0%
2485059 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.58 48.0 3.87e-01 98.1% 48.2%
4979212 2011.1.1.0 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases 0.58 49.0 3.12e-01 100.0% 84.4%
4937786 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.57 45.0 3.75e-01 90.4% 74.0%
4629521 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.57 48.0 3.92e-01 98.1% 51.9%
2440709 205.1.1.14 ↗ a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_2 0.57 39.0 3.88e-01 75.0% 75.4%
4944847 304.5.1.0 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.57 47.0 3.87e-01 98.1% 51.0%
3926149 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.56 45.0 3.44e-01 100.0% 40.0%
5082567 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.56 45.0 3.21e-01 98.1% 76.8%
5040667 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.56 46.0 3.79e-01 98.1% 52.4%
4483987 374.1.1.2 ↗ few secondary structure elements › HIPIP (high potential iron protein) › HIPIP (high potential iron protein) › HIPIP (high potential iron protein) › BssC_TutF 0.55 39.0 3.84e-01 82.7% 69.1%
3728856 171.1.1.9 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3, Ribonucleas_3_3 0.55 49.0 3.20e-01 100.0% 76.0%
4518553 223.1.1.2 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains › PAS 0.55 44.0 3.40e-01 90.4% 44.2%
3350925 2004.1.1.19 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.54 36.0 2.32e-01 86.5% 16.4%
3701882 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.54 39.0 3.23e-01 100.0% 42.1%
3404903 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.54 48.0 3.23e-01 100.0% 82.1%
5049862 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.54 41.0 2.92e-01 84.6% 52.0%
3320639 314.1.1.0 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases 0.53 42.0 2.87e-01 90.4% 92.3%
3291254 2004.1.1.286 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TraG-D_C 0.53 44.0 2.57e-01 98.1% 59.1%
4957224 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.53 38.0 3.09e-01 75.0% 39.0%
5038160 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.53 37.0 3.06e-01 75.0% 39.0%
3491344 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.53 35.0 3.11e-01 75.0% 42.9%
1815422 566.1.1.3 ↗ alpha complex topology › P40 nucleoprotein-like › P40 nucleoprotein-related › P40 nucleoprotein-related › Pneumo_ncap 0.52 45.0 2.99e-01 100.0% 43.2%
3725909 284.1.3.1 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › SNF5 0.52 35.0 2.93e-01 80.8% 39.4%
4405445 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.52 42.0 3.92e-01 98.1% 100.0%
3636696 3745.1.1.1 ↗ alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex 0.51 44.0 2.64e-01 100.0% 69.6%
3959362 101.1.1.531 ↗ alpha arrays › HTH › HTH › Three-helical HTH › WS_DGAT_cat 0.51 41.0 2.96e-01 88.5% 36.7%
3689293 284.1.3.1 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › SNF5 0.51 34.0 3.04e-01 78.8% 47.4%
D4 medium residues 53-127
PDB
Domain cluster: representative
CATH (60)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.90 62.0 6.84e-01 70.7% 87.1%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.89 61.0 5.53e-01 70.7% 54.6%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.88 63.0 6.41e-01 73.3% 79.5%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.88 60.0 5.91e-01 70.7% 66.7%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.88 62.0 4.85e-01 72.0% 38.3%
3b2eF00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.88 62.0 6.86e-01 73.3% 90.3%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.87 61.0 6.37e-01 72.0% 82.6%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.87 60.0 6.17e-01 70.7% 74.6%
3sfvB02 6.10.140.2010 Special › Helix non-globular › Helix Hairpins › 0.86 66.0 4.69e-01 80.0% 72.0%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.86 61.0 6.44e-01 73.3% 89.6%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.85 60.0 5.62e-01 73.3% 64.8%
6f1eA01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.85 59.0 4.70e-01 72.0% 39.6%
2gv9A05 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.84 58.0 6.45e-01 73.3% 89.8%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.84 60.0 6.00e-01 73.3% 73.7%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.84 58.0 5.22e-01 72.0% 57.8%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.84 59.0 4.42e-01 73.3% 33.5%
4akgA04 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.84 59.0 4.52e-01 73.3% 40.4%
4q20A01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.83 59.0 5.71e-01 73.3% 70.7%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.83 59.0 5.85e-01 73.3% 77.9%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.83 59.0 4.87e-01 73.3% 79.0%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.83 57.0 5.85e-01 70.7% 74.6%
6gyhA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.82 63.0 4.36e-01 80.0% 90.7%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.82 58.0 5.20e-01 73.3% 73.5%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.82 51.0 5.98e-01 74.7% 92.2%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.81 56.0 3.59e-01 72.0% 16.6%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.80 57.0 5.18e-01 74.7% 56.6%
4kw3A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.80 73.0 4.90e-01 100.0% 28.6%
6umqA01 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.80 59.0 5.09e-01 78.7% 89.6%
1luwA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.79 54.0 5.79e-01 70.7% 92.2%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 57.0 4.34e-01 74.7% 64.0%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.78 55.0 5.76e-01 73.3% 92.6%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.78 56.0 5.01e-01 74.7% 54.9%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 54.0 4.79e-01 72.0% 61.0%
4nwpD00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.78 59.0 4.61e-01 80.0% 75.2%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.77 58.0 4.22e-01 80.0% 77.5%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 53.0 5.12e-01 72.0% 63.9%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.76 66.0 4.62e-01 92.0% 78.8%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 53.0 4.76e-01 73.3% 53.5%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.75 57.0 5.16e-01 81.3% 99.0%
3p42A02 6.10.250.2280 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.75 53.0 5.55e-01 74.7% 100.0%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 51.0 4.61e-01 70.7% 53.5%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.74 52.0 4.97e-01 74.7% 63.2%
2gsqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.73 50.0 4.52e-01 73.3% 50.9%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.72 49.0 4.25e-01 70.7% 65.5%
2b3tB01 6.10.140.1980 Special › Helix non-globular › Helix Hairpins › 0.72 50.0 5.30e-01 72.0% 92.3%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.70 50.0 4.13e-01 74.7% 43.6%
3x3bA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.70 62.0 4.19e-01 98.7% 80.1%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.70 62.0 4.41e-01 97.3% 86.4%
2psmA00 1.20.1250.70 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 0.69 50.0 4.31e-01 76.0% 70.1%
3h6pC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.69 46.0 5.17e-01 70.7% 91.1%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.69 61.0 4.94e-01 93.3% 73.1%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.68 52.0 4.43e-01 82.7% 50.8%
2etnB01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.67 59.0 5.94e-01 96.0% 92.1%
1ucuA01 6.10.280.190 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 46.0 4.77e-01 73.3% 86.8%
1rtwB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.66 60.0 4.31e-01 100.0% 84.6%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 46.0 3.89e-01 74.7% 44.5%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.64 57.0 4.64e-01 94.7% 63.8%
2wwxB00 1.20.1260.70 Mainly Alpha › Up-down Bundle › Ferritin › 0.64 43.0 3.22e-01 74.7% 26.5%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.57 49.0 4.02e-01 93.3% 90.2%
3ayhA00 1.20.1250.40 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › RNA Polymerase II, Rpb4 subunit 0.54 46.0 3.83e-01 96.0% 56.7%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4336724 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.90 64.0 5.49e-01 73.3% 73.6%
3702979 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.90 63.0 3.77e-01 72.0% 12.4%
4039014 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.90 63.0 5.38e-01 73.3% 49.1%
4266268 192.8.1.376 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › RRP36 0.90 63.0 4.80e-01 72.0% 36.0%
3927560 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.90 62.0 6.87e-01 70.7% 88.3%
3469530 3274.1.1.1 ↗ extended segments › N-terminal region in 40S ribosomal protein rpS2 (S5p) › N-terminal region in 40S ribosomal protein rpS2 (S5p) › N-terminal region in 40S ribosomal protein rpS2 (S5p) › Ribosomal_S5 0.90 62.0 4.93e-01 72.0% 38.6%
4405928 5086.1.1.196 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YknX 0.89 63.0 6.59e-01 73.3% 81.4%
3391706 192.5.1.0 ↗ alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.89 63.0 5.09e-01 73.3% 43.8%
3908132 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.89 62.0 4.13e-01 73.3% 21.3%
4572664 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.89 62.0 6.44e-01 73.3% 77.1%
3811563 4207.1.2.0 ↗ alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.89 63.0 5.16e-01 73.3% 45.6%
4952010 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.88 62.0 6.21e-01 72.0% 76.0%
3297534 330.1.1.2 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Ribosomal_S5 0.88 63.0 4.68e-01 73.3% 35.2%
3512620 3755.4.1.1 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 0.88 62.0 4.71e-01 73.3% 36.3%
4941665 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.88 62.0 6.49e-01 73.3% 81.2%
4984327 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.87 62.0 5.42e-01 73.3% 77.1%
3906631 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.87 62.0 5.31e-01 73.3% 75.5%
3608554 3291.1.1.1 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.87 61.0 4.78e-01 73.3% 39.3%
3731974 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.87 60.0 5.20e-01 72.0% 50.9%
5012794 4333.1.1.0 ↗ a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain 0.86 61.0 3.82e-01 73.3% 29.6%
3286299 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.86 62.0 5.36e-01 74.7% 50.9%
4965021 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.86 59.0 6.76e-01 70.7% 96.4%
3794795 603.1.1.3 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.85 60.0 5.41e-01 73.3% 57.0%
4220356 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.85 60.0 3.81e-01 73.3% 17.0%
3838686 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.85 58.0 6.48e-01 70.7% 88.3%
3583890 603.1.1.3 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.85 60.0 4.71e-01 73.3% 37.9%
3636298 5001.1.1.6 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin 0.85 63.0 4.26e-01 77.3% 80.4%
3717206 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.85 60.0 5.09e-01 73.3% 68.7%
3695552 5001.1.1.6 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin 0.84 64.0 4.24e-01 80.0% 78.4%
1685299 6110.1.1.0 ↗ alpha superhelices › Linker domain of cytoplasmic dynein heavy chain › Linker domain of cytoplasmic dynein heavy chain › Linker domain of cytoplasmic dynein heavy chain 0.84 60.0 4.20e-01 73.3% 30.4%
5035167 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.84 59.0 3.63e-01 73.3% 14.3%
3242683 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.84 64.0 5.98e-01 80.0% 77.8%
1821875 4970.1.1.1 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.84 57.0 6.32e-01 73.3% 88.1%
3916825 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 59.0 4.60e-01 73.3% 38.0%
3607135 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.84 59.0 4.77e-01 73.3% 76.3%
1544900 5001.1.1.6 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin 0.84 64.0 4.37e-01 80.0% 86.4%
3614667 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.84 61.0 3.84e-01 76.0% 40.6%
3575178 616.1.1.30 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Neur_chan_memb 0.83 59.0 5.92e-01 73.3% 73.3%
3797638 3456.1.1.0 ↗ extended segments › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A 0.82 58.0 4.97e-01 73.3% 51.3%
3194783 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.82 57.0 4.86e-01 72.0% 51.3%
3353220 4207.1.1.0 ↗ alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.80 57.0 5.02e-01 73.3% 61.9%
3962893 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.80 55.0 5.11e-01 74.7% 56.8%
3399242 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.79 59.0 5.06e-01 78.7% 52.7%
3991274 3291.1.1.137 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Patched 0.78 55.0 4.42e-01 73.3% 39.3%
3183519 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.77 53.0 6.06e-01 74.7% 96.4%
3503536 3711.1.1.38 ↗ alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › Patched 0.76 55.0 5.14e-01 74.7% 76.7%
4154189 3281.1.1.2 ↗ alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M,Proton_antipo_N 0.76 53.0 3.08e-01 73.3% 18.3%
3265040 150.2.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Cobalamin adenosyltransferase › Cobalamin adenosyltransferase › Cob_adeno_trans 0.75 64.0 4.54e-01 93.3% 63.2%
3180974 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.75 52.0 5.84e-01 76.0% 98.2%
3916832 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.72 61.0 5.25e-01 98.7% 59.1%
4954892 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.72 62.0 3.85e-01 90.7% 41.1%
4022294 1025.1.1.0 ↗ alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain 0.72 53.0 4.80e-01 80.0% 85.7%
4942772 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.71 48.0 5.05e-01 70.7% 80.0%
3698212 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.71 64.0 4.02e-01 96.0% 77.9%
3180530 3711.1.1.0 ↗ alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.70 64.0 5.57e-01 100.0% 88.2%
5001442 601.19.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.69 51.0 3.42e-01 77.3% 20.4%
3735658 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.69 63.0 5.42e-01 100.0% 73.0%
4017831 4970.1.1.0 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.65 49.0 3.87e-01 80.0% 51.0%
D5 medium residues 128-220
PDB
Domain cluster: rep: NS2__YP_009227290__Rat_bocavirus__1788315__D217-273