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NS2
Euk-VirRat_bocavirus
NS2__YP_009227290__Rat_bocavirus__1788315
Identity
- Accession:
- YP_009227290 ↗
- Protein ID:
- NS2
- Kingdom:
- euk
Quality
79.6
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Quintoviricetes›
Piccovirales›
Parvoviridae›
Bocaparvovirus›
Rat_bocavirus
TaxID: 1788315
Cluster
View cluster (44 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 313-370
Domain cluster:
rep: non-structural_protein_1__YP_009272913__Mink_bocavirus_1__2259808__D352-409
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01057.24 best | Parvo_NS1 | 21.6 | 1.40e-04 | 100.0% | 18.8% |
D2
high
residues 387-609
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01057.24 best | Parvo_NS1 | 249.6 | 3.90e-74 | 88.8% | 67.2% |
| PF00519.24 | PPV_E1_C | 27.1 | 3.30e-06 | 75.3% | 52.6% |
D3
medium
residues 11-32_109-129_194-216
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2x3gA00 | 3.30.70.1910 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 53.0 | 4.40e-01 | 95.5% | 89.7% |
| 4za1C00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 42.0 | 3.72e-01 | 74.2% | 100.0% |
| 4i6yA02 | 3.30.70.420 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain | 0.54 | 38.0 | 3.19e-01 | 72.7% | 100.0% |
| 1tz0B00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 36.0 | 3.20e-01 | 72.7% | 94.8% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3533042 | 304.5.1.0 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like | 0.57 | 41.0 | 3.66e-01 | 77.3% | 84.2% |
| 4877694 | 304.51.1.3 ↗ | a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR_assoc | 0.54 | 37.0 | 3.08e-01 | 71.2% | 96.6% |
| 3456323 | 11.1.5.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f | 0.54 | 30.0 | 2.59e-01 | 95.5% | 32.4% |
| 4098707 | 304.159.1.1 ↗ | a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB › Lant_dehydr_C | 0.53 | 39.0 | 3.36e-01 | 77.3% | 92.0% |
| 1681454 | 304.166.1.9 ↗ | a+b two layers › Alpha-beta plaits › Nup54 ferredoxin-like domain › Nup54 ferredoxin-like domain › PF29949 | 0.53 | 37.0 | 3.16e-01 | 75.8% | 74.1% |
| 3281255 | 101.1.2.742 ↗ | alpha arrays › HTH › HTH › winged helix domain › DUF7782 | 0.50 | 42.0 | 3.57e-01 | 100.0% | 92.5% |
D4
medium
residues 33-108_130-193
Domain cluster:
rep: NS1__YP_009552695__Rhinolophus_pusillus_bocaparvovirus_1__2053079__D4-183
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4kw3A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.86 | 81.0 | 6.40e-01 | 100.0% | 62.8% |
| 2lt3A01 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.60 | 29.0 | 3.35e-01 | 83.6% | 63.0% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.57 | 30.0 | 3.92e-01 | 85.0% | 93.3% |
| 3k1zA02 | 1.10.150.720 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Haloacid dehalogenase-like hydrolase | 0.56 | 33.0 | 4.10e-01 | 100.0% | 97.6% |
| 2fzfA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 45.0 | 4.43e-01 | 96.4% | 82.7% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 40.0 | 4.12e-01 | 97.1% | 80.7% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.52 | 35.0 | 3.88e-01 | 97.1% | 86.2% |
| 4a25B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 42.0 | 4.06e-01 | 97.1% | 75.2% |
| 5ffdA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 40.0 | 4.06e-01 | 97.1% | 83.2% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 34.0 | 3.88e-01 | 86.4% | 89.5% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 39.0 | 3.85e-01 | 97.1% | 74.0% |
| 7yu4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 44.0 | 3.63e-01 | 95.7% | 79.4% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.50 | 35.0 | 3.88e-01 | 90.7% | 90.8% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3489579 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.59 | 48.0 | 3.35e-01 | 88.6% | 85.9% |
| 3764108 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 49.0 | 3.44e-01 | 89.3% | 76.8% |
| 3288812 | 5050.1.1.55 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr, MFS_1 | 0.56 | 42.0 | 2.93e-01 | 77.9% | 37.9% |
| 3763723 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.55 | 39.0 | 3.98e-01 | 97.1% | 73.6% |
| 3879373 | 621.1.1.1 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › GBP_C | 0.54 | 39.0 | 2.91e-01 | 75.0% | 81.1% |
| 4950677 | 1075.1.1.3 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 | 0.53 | 44.0 | 3.61e-01 | 89.3% | 66.0% |
| 3667525 | 109.4.1.1656 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27769 | 0.53 | 38.0 | 3.20e-01 | 73.6% | 90.6% |
| 3929291 | 1076.1.1.2 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Aph-1 | 0.53 | 43.0 | 3.88e-01 | 87.9% | 80.5% |
| 3786455 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.51 | 45.0 | 3.62e-01 | 100.0% | 93.0% |
| 3271583 | 1075.1.1.25 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › EMP70 | 0.50 | 45.0 | 3.41e-01 | 100.0% | 91.6% |
D5
medium
residues 217-273
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4kw3A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.96 | 90.0 | 5.57e-01 | 100.0% | 21.8% |
| 6bfnB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.56 | 42.0 | 2.99e-01 | 84.2% | 65.3% |
| 1xx1A00 | 3.20.20.190 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphatidylinositol (PI) phosphodiesterase | 0.55 | 46.0 | 3.05e-01 | 100.0% | 92.3% |
| 4qa9A00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.53 | 40.0 | 2.57e-01 | 93.0% | 75.5% |
| 3fj1A02 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.52 | 42.0 | 3.39e-01 | 100.0% | 92.6% |