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NS2_protein

Euk-Vir

Rice_hoja_blanca_tenuivirus

NS2_protein__YP_009449441__Rice_hoja_blanca_tenuivirus__12332

Identity

Accession:
YP_009449441 ↗
Protein ID:
NS2_protein
Kingdom:
euk

Quality

77.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-76
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05310.18 best Tenui_NS3 68.2 1.50e-18 100.0% 33.9%
CATH (42)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.78 67.0 5.06e-01 92.8% 46.2%
6ljaA01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.73 63.0 3.93e-01 94.2% 33.9%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 62.0 6.11e-01 94.2% 89.3%
3qmlD00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.71 48.0 3.21e-01 71.0% 27.8%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 63.0 4.78e-01 97.1% 91.0%
1y6xA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.70 49.0 4.52e-01 72.5% 60.9%
6orcB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 49.0 3.96e-01 87.0% 38.8%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.69 57.0 5.02e-01 92.8% 62.9%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 59.0 4.66e-01 97.1% 89.6%
7e9uA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.68 56.0 3.43e-01 92.8% 31.0%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.67 55.0 5.43e-01 94.2% 92.0%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.67 56.0 4.61e-01 95.7% 63.1%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 55.0 4.63e-01 94.2% 90.2%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 55.0 5.68e-01 100.0% 95.4%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.66 58.0 5.15e-01 100.0% 69.1%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.66 47.0 4.14e-01 75.4% 91.2%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.65 52.0 4.38e-01 88.4% 69.2%
2l6jA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 54.0 4.62e-01 100.0% 57.7%
2lseA00 1.20.120.1360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.64 55.0 4.91e-01 100.0% 70.3%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.64 56.0 4.73e-01 98.6% 81.9%
3tahA02 1.10.287.1770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 46.0 4.25e-01 100.0% 60.2%
1tqnA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.63 52.0 3.17e-01 91.3% 24.4%
7nc3F01 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 47.0 4.06e-01 82.6% 70.2%
3eslA01 1.20.58.2070 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 50.0 4.95e-01 98.6% 85.3%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.62 54.0 4.57e-01 100.0% 81.5%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.61 53.0 4.43e-01 100.0% 55.6%
7sf7A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 51.0 3.44e-01 94.2% 72.0%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 45.0 3.93e-01 82.6% 67.3%
1q2lA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.60 42.0 2.94e-01 73.9% 56.7%
6xm1A02 3.90.830.10 Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a 0.60 53.0 4.54e-01 100.0% 65.5%
1v4aA01 1.10.4050.10 Mainly Alpha › Orthogonal Bundle › Nucleotidyltransferase substrate binding subunit/domain fold › Glutamine synthase adenylyltransferase GlnE 0.60 43.0 3.67e-01 75.4% 52.3%
2wzkA01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.60 45.0 3.73e-01 81.2% 78.0%
7ep1B01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.59 45.0 3.22e-01 87.0% 40.1%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.57 51.0 4.84e-01 98.6% 86.7%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.57 47.0 4.27e-01 98.6% 84.3%
2hsnA02 1.20.1050.110 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 48.0 4.22e-01 97.1% 72.0%
7xxiA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 47.0 3.16e-01 100.0% 66.9%
4gx0A01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 44.0 3.87e-01 100.0% 59.2%
6wlvB01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 44.0 3.06e-01 100.0% 25.4%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.54 45.0 4.21e-01 97.1% 88.5%
8ctsB01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 38.0 3.62e-01 100.0% 62.1%
4dvgB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.52 44.0 2.97e-01 100.0% 28.9%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4031537 159.1.2.0 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related 0.77 54.0 4.69e-01 72.5% 61.0%
3710592 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.75 54.0 4.83e-01 75.4% 68.4%
3520105 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.75 68.0 5.18e-01 100.0% 60.6%
3711833 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.73 66.0 4.95e-01 100.0% 55.2%
5053401 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.72 61.0 6.14e-01 92.8% 91.4%
3926402 639.2.1.0 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.72 65.0 6.17e-01 100.0% 83.7%
3880747 109.59.1.21 alpha superhelices › Repetitive alpha hairpins › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Intraflagellar transport protein 80 (IFT80) C-terminal domain › ARM_KNTC1_1st 0.71 55.0 4.12e-01 84.1% 36.5%
4955536 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.70 63.0 4.36e-01 98.6% 87.3%
3507458 109.24.1.0 alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 0.69 60.0 5.48e-01 94.2% 91.1%
3693645 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.68 59.0 4.70e-01 100.0% 76.7%
4331100 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.68 58.0 5.20e-01 92.8% 82.1%
3382017 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 58.0 3.37e-01 91.3% 18.8%
3242490 109.21.1.1 alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleopor_Nup85 0.68 59.0 3.44e-01 95.7% 13.3%
3572645 2484.1.1.198 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Dimer_Tnp_hAT, DUF4371 0.68 59.0 3.61e-01 100.0% 19.6%
4960288 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.66 57.0 4.23e-01 95.7% 47.4%
4272154 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 53.0 4.75e-01 91.3% 64.2%
3189830 109.4.1.507 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3632 0.65 59.0 3.40e-01 100.0% 22.0%
3629379 3599.1.1.1 alpha superhelices › Mitochondrial malonyl-CoA decarboxylase helical domain › Mitochondrial malonyl-CoA decarboxylase helical domain › Mitochondrial malonyl-CoA decarboxylase helical domain › MCD_N 0.64 58.0 4.54e-01 98.6% 100.0%
3374304 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.64 56.0 5.33e-01 97.1% 95.0%
3453205 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.64 56.0 4.49e-01 100.0% 85.7%
3628093 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.63 57.0 4.91e-01 98.6% 76.2%
3309012 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.62 54.0 4.61e-01 98.6% 70.4%
3264732 109.4.1.128 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G_like_2 0.62 54.0 3.74e-01 100.0% 51.6%
3447988 603.1.1.102 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF3537 0.61 55.0 3.96e-01 100.0% 57.9%
3276574 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.61 49.0 3.55e-01 91.3% 40.2%
3669701 603.1.1.160 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 14-3-3 0.60 51.0 4.38e-01 97.1% 83.5%
3579241 192.29.1.50 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PTPLA 0.59 46.0 4.04e-01 89.9% 71.3%
3297453 192.17.1.0 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like 0.56 50.0 4.59e-01 100.0% 92.2%
3812592 109.4.1.1948 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Zw10_middle 0.54 44.0 3.50e-01 100.0% 41.2%
3198235 109.4.1.307 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tho2 0.54 46.0 3.16e-01 98.6% 51.6%
3267295 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.52 43.0 3.10e-01 92.8% 42.9%
D2 high residues 97-191
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05310.18 best Tenui_NS3 116.1 3.00e-33 81.0% 41.4%
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1st0A02 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.69 56.0 4.48e-01 87.4% 57.6%
2ymvA02 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.68 48.0 3.68e-01 74.7% 73.2%
4aqcB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.61 43.0 4.29e-01 72.6% 79.2%
1f94A00 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.57 35.0 4.06e-01 82.1% 90.5%
2yocB05 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.57 41.0 3.88e-01 74.7% 83.9%
7zhdA01 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.57 39.0 3.50e-01 72.6% 87.3%
5eokA04 3.50.4.10 Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor 0.56 40.0 4.22e-01 74.7% 91.6%
1l2mA00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.56 41.0 3.82e-01 76.8% 90.7%
5xbtA01 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.55 39.0 3.43e-01 74.7% 88.4%
2vfrA03 3.30.70.2530 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 32.0 3.38e-01 86.3% 67.8%
2r99A00 2.40.100.10 Mainly Beta › Beta Barrel › Cyclophilin › Cyclophilin-like 0.52 46.0 3.83e-01 97.9% 92.7%
4rudA00 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.51 29.0 3.48e-01 82.1% 89.7%
5jheA01 2.40.100.10 Mainly Beta › Beta Barrel › Cyclophilin › Cyclophilin-like 0.51 45.0 3.54e-01 97.9% 91.0%
1lvoA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.51 33.0 3.45e-01 92.6% 70.5%
1lopA00 2.40.100.10 Mainly Beta › Beta Barrel › Cyclophilin › Cyclophilin-like 0.50 44.0 3.70e-01 97.9% 94.5%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3481720 312.1.1.8 a+b three layers › HIT-like › HIT-related › HIT-related › DcpS_C 0.71 58.0 4.38e-01 87.4% 59.1%
3733772 312.1.1.6 a+b three layers › HIT-like › HIT-related › HIT-related › CwfJ_C_2,CwfJ_C_1 0.63 57.0 4.20e-01 100.0% 83.6%
3966291 886.1.1.0 a+b duplicates or obligate multimers › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain 0.62 43.0 3.61e-01 70.5% 97.5%
3585693 390.1.1.0 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.59 40.0 4.09e-01 70.5% 84.2%
3912756 886.1.1.1 a+b duplicates or obligate multimers › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › SOUL 0.59 41.0 3.35e-01 73.7% 85.8%
3271482 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.58 41.0 3.06e-01 72.6% 96.7%
3934532 390.1.1.1 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 0.58 40.0 4.16e-01 70.5% 95.3%
4991759 886.1.1.2 a+b duplicates or obligate multimers › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › GyrI-like 0.56 42.0 3.92e-01 78.9% 87.5%
3304921 390.1.1.6 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_2 0.55 38.0 3.89e-01 71.6% 75.6%
3622117 12.1.1.35 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Melibiase_C 0.54 39.0 3.84e-01 74.7% 94.0%
3619322 390.1.1.0 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.54 37.0 3.73e-01 71.6% 83.0%
3301800 390.1.1.6 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_2 0.53 37.0 3.83e-01 71.6% 81.2%
3795859 390.1.1.0 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.53 37.0 3.80e-01 72.6% 87.8%
3575159 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 36.0 3.55e-01 71.6% 66.7%
3837237 70.3.1.1 beta barrels › beta-clip › SET domain-like › SET domain-like › SET 0.52 37.0 2.68e-01 74.7% 86.4%
3512295 382.1.1.0 few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like 0.52 41.0 3.80e-01 87.4% 91.1%
3335593 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.50 45.0 2.92e-01 100.0% 29.0%
5054721 210.1.3.3 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.50 36.0 2.76e-01 76.8% 87.9%
3573582 390.1.1.0 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.50 34.0 3.51e-01 70.5% 85.6%