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NS3-like_protein

Euk-Vir

Wuhan_flea_virus

NS3-like_protein__YP_009179404__Wuhan_flea_virus__1746071

Identity

Accession:
YP_009179404 ↗
Protein ID:
NS3-like_protein
Kingdom:
euk

Quality

66.3 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Flasuviricetes› Amarillovirales› Flaviviridae› Wuhan_flea_virus

TaxID: 1746071

Cluster

View cluster (5 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 150-309
PDB
D2 high residues 323-393
PDB
Domain cluster: representative
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1lvoA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.84 71.0 6.54e-01 100.0% 72.7%
2wv9A01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.82 76.0 5.58e-01 100.0% 41.9%
4m9fA00 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.79 72.0 5.13e-01 100.0% 36.0%
4r8tB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.78 63.0 6.27e-01 100.0% 83.6%
2odpA03 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.77 70.0 5.26e-01 100.0% 67.3%
2w5eA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.76 60.0 5.98e-01 100.0% 83.8%
1wqsA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.76 68.0 6.00e-01 100.0% 85.4%
2aq6A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.75 66.0 5.32e-01 100.0% 81.1%
3u5wA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.75 66.0 5.49e-01 100.0% 77.0%
2fhqA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.73 65.0 5.28e-01 100.0% 74.8%
2fg9A01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.73 65.0 5.00e-01 100.0% 73.6%
3db0B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.73 65.0 5.40e-01 100.0% 80.6%
3cp3A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.73 64.0 5.36e-01 100.0% 76.4%
2hq7B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.73 65.0 5.17e-01 100.0% 72.5%
2hq9B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.73 65.0 5.22e-01 100.0% 78.8%
4ybnB00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.72 64.0 4.62e-01 100.0% 59.0%
2ol5A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.72 63.0 4.69e-01 100.0% 68.9%
2htiA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.71 63.0 5.26e-01 100.0% 77.8%
3ec6A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.71 63.0 5.21e-01 100.0% 77.3%
2htdB00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.71 62.0 5.21e-01 100.0% 75.8%
3in6A02 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.71 61.0 5.28e-01 100.0% 88.9%
2asfA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.70 61.0 5.13e-01 100.0% 80.0%
3r5lA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.69 61.0 5.21e-01 100.0% 89.7%
3cp7B02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 61.0 5.36e-01 100.0% 73.3%
3cp7A01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 59.0 5.21e-01 100.0% 79.3%
5tr9A01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.67 52.0 4.72e-01 84.5% 67.7%
6mv2A02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.67 50.0 4.44e-01 81.7% 72.4%
2bhgA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.66 58.0 5.20e-01 100.0% 71.6%
1ylnA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.66 58.0 5.00e-01 100.0% 73.7%
5hmaA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.65 55.0 5.19e-01 100.0% 79.3%
2eixA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.63 52.0 4.61e-01 94.4% 67.9%
1kkeA02 2.60.90.20 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Virus attachment protein , globular domain 0.60 53.0 4.26e-01 100.0% 91.5%
1im3D00 2.60.40.1200 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 43.0 4.02e-01 83.1% 67.4%
1wruA01 2.30.300.10 Mainly Beta › Roll › Phage tail proteins - horseshoe like beta roll fold › Baseplate protein-like domain - beta roll fold 0.58 49.0 3.79e-01 100.0% 46.9%
3n7lA02 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.57 46.0 3.46e-01 90.1% 86.7%
3cddA01 2.30.300.10 Mainly Beta › Roll › Phage tail proteins - horseshoe like beta roll fold › Baseplate protein-like domain - beta roll fold 0.55 47.0 3.57e-01 100.0% 47.3%
2dhkA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.55 40.0 3.56e-01 77.5% 84.0%
4lrzE02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.55 37.0 3.42e-01 100.0% 53.2%
2eqkA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.52 35.0 3.56e-01 70.4% 69.9%
2l5pA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.52 37.0 2.90e-01 77.5% 70.9%
1dfvA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.51 34.0 2.70e-01 70.4% 83.8%
2f8xC03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 40.0 3.71e-01 87.3% 69.1%
3wnkA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.51 44.0 3.73e-01 100.0% 65.6%
1dn0D02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 38.0 3.51e-01 83.1% 69.1%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
None — 0.84 78.0 5.76e-01 100.0% 43.4%
3225260 1.1.17.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › DUF316 0.77 70.0 4.66e-01 100.0% 28.7%
3960372 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.77 65.0 6.10e-01 100.0% 76.5%
3283546 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.77 68.0 5.42e-01 100.0% 67.1%
3507692 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.76 68.0 5.35e-01 100.0% 60.7%
5051898 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.76 67.0 5.32e-01 100.0% 67.6%
3950388 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.76 67.0 5.29e-01 100.0% 78.4%
4979014 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.76 68.0 5.46e-01 100.0% 76.3%
4961770 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.76 67.0 5.56e-01 100.0% 82.4%
5016426 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.75 67.0 5.15e-01 100.0% 78.0%
3229859 1.1.17.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › DUF316 0.75 67.0 4.55e-01 100.0% 28.2%
3787756 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.74 66.0 5.10e-01 100.0% 77.2%
4998991 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.74 66.0 5.29e-01 100.0% 82.9%
4926888 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.74 66.0 5.41e-01 100.0% 81.5%
4982411 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.74 65.0 5.39e-01 100.0% 79.2%
170199 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.74 66.0 4.66e-01 100.0% 35.6%
4944685 1.1.5.18 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › FMN_bind_2 0.74 65.0 5.13e-01 100.0% 80.7%
5048653 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.73 64.0 5.03e-01 100.0% 78.7%
4947401 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.73 64.0 5.04e-01 100.0% 78.1%
4997723 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.73 65.0 5.06e-01 100.0% 78.1%
3234951 1.1.17.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › DUF316 0.73 66.0 4.47e-01 100.0% 28.8%
3510207 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.73 65.0 4.77e-01 100.0% 41.6%
3514672 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.73 65.0 4.99e-01 100.0% 78.1%
4960378 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.73 64.0 5.12e-01 100.0% 77.9%
4514555 1.1.5.18 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › FMN_bind_2 0.72 64.0 4.68e-01 100.0% 68.7%
4125768 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.72 64.0 5.05e-01 100.0% 78.0%
4962621 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.72 64.0 5.13e-01 100.0% 80.0%
3615659 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.72 49.0 3.57e-01 70.4% 87.4%
5062740 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.72 64.0 4.73e-01 100.0% 65.4%
5004573 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.72 63.0 5.01e-01 100.0% 73.8%
4400460 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.72 63.0 5.09e-01 100.0% 74.3%
163486 1.1.5.18 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › FMN_bind_2 0.72 63.0 4.69e-01 100.0% 68.9%
4981706 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.72 63.0 4.95e-01 100.0% 78.6%
5047862 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.72 63.0 5.01e-01 100.0% 74.3%
5021355 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.71 63.0 4.99e-01 100.0% 74.3%
3953421 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.71 63.0 5.08e-01 100.0% 73.6%
3286417 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.71 62.0 5.21e-01 100.0% 82.4%
5019852 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.71 63.0 4.51e-01 100.0% 37.6%
4129418 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.71 62.0 5.09e-01 100.0% 74.1%
3246847 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.71 60.0 4.37e-01 100.0% 34.4%
4331393 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.70 62.0 4.99e-01 100.0% 75.0%
4521524 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.70 62.0 5.00e-01 100.0% 72.9%
4963864 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.70 60.0 4.97e-01 100.0% 81.5%
3385776 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.69 60.0 4.95e-01 100.0% 74.1%
3518574 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.69 61.0 4.76e-01 100.0% 55.5%
4008655 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.69 59.0 4.80e-01 100.0% 71.7%
3288278 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.69 61.0 4.94e-01 100.0% 73.3%
3066474 1.1.17.2 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_C3 0.68 60.0 4.29e-01 100.0% 36.1%
5039871 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.66 58.0 3.98e-01 100.0% 31.5%
4382401 1.1.7.100 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PGBA_N 0.65 48.0 4.59e-01 81.7% 67.1%
3504760 1.1.8.5 ↗ beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain › tRNA_Me_trans_C 0.65 51.0 4.79e-01 94.4% 68.9%
4656452 1.1.13.63 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Queuosine_synth 0.64 55.0 4.60e-01 100.0% 55.4%
4108039 1.1.8.5 ↗ beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain › tRNA_Me_trans_C 0.61 45.0 4.34e-01 83.1% 68.2%
4152684 1.1.8.5 ↗ beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain › tRNA_Me_trans_C 0.60 46.0 4.50e-01 95.8% 76.9%
3623013 11.1.1.179 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3 0.59 46.0 4.17e-01 84.5% 63.2%
3905148 11.1.1.96 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › C1-set 0.57 42.0 3.96e-01 81.7% 68.9%
3961371 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.57 46.0 4.50e-01 98.6% 81.2%
3642679 220.1.1.78 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_2 0.54 41.0 3.67e-01 85.9% 74.1%
3861569 220.1.1.56 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › ASK_PH 0.52 37.0 3.30e-01 77.5% 77.4%
3224516 11.1.1.214 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Pur_ac_phosph_N 0.51 39.0 3.76e-01 85.9% 74.1%
3284488 331.3.1.11 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 0.51 38.0 3.00e-01 78.9% 62.8%
3980680 3308.2.1.2 ↗ beta duplicates or obligate multimers › periplasmic lysozyme inhibitor of I-type lysozyme-like › XAC2610 protein › XAC2610 protein › PF27031 0.50 39.0 3.02e-01 85.9% 74.1%
D3 high residues 405-534
PDB
Domain cluster: rep: B962L__YP_009703129__African_swine_fever_virus__10497__D53-65_81-193
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF07652.21 best Flavi_DEAD 72.9 3.90e-20 99.2% 78.4%
PF04851.22 ResIII 24.6 3.00e-05 89.2% 66.5%
PF00270.36 DEAD 36.6 5.50e-09 86.2% 64.1%
D4 high residues 549-684
PDB
Domain cluster: rep: B962L__YP_009703129__African_swine_fever_virus__10497__D237-425
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00271.38 best Helicase_C 41.6 1.80e-10 88.2% 90.9%
D5 medium residues 16-115
PDB
D6 medium residues 702-793
PDB