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NS3

Euk-Vir

Simian_pegivirus

NS3__YP_009045177__Simian_pegivirus__1454041

Identity

Accession:: YP_009045177 ↗
Protein ID:: NS3
Kingdom:: euk

Quality

86.6 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Flasuviricetes› Amarillovirales› Flaviviridae› Pegivirus› Simian_pegivirus

TaxID: 1454041

Cluster

View cluster (30 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 184-323

PDB

Domain cluster: rep: B962L__YP_009703129__African_swine_fever_virus__10497__D53-65_81-193

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00270.36 best	DEAD	28.4	1.80e-06	86.4%	65.3%

D2 high residues 337-433_447-474

PDB

Domain cluster: rep: B962L__YP_009703129__African_swine_fever_virus__10497__D237-425

D3 high residues 498-618

PDB

Domain cluster: rep: putative_NS3_protein__YP_007905979__Rodent_pegivirus__1321391__D503-601

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF22027.2 best	NS3_helicase_C	35.2	1.80e-08	98.4%	82.3%

D4 medium residues 1-100

PDB

Domain cluster: rep: non-structural_protein_NS3__NP_775507__Tick-borne_encephalitis_virus__11084__D2-87

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02907.22 best	Peptidase_S29	100.1	1.40e-28	72.0%	47.0%

CATH (23)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2o8mB01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.95	62.0	7.67e-01	80.0%	100.0%
4b6eB01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.83	75.0	5.76e-01	94.0%	47.5%
3su0A01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.83	74.0	7.09e-01	93.0%	93.8%
1befA01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.81	61.0	6.38e-01	93.0%	84.8%
2w5eA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.72	46.0	5.62e-01	77.0%	100.0%
1l1jA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.65	52.0	4.89e-01	84.0%	92.4%
4rqyA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.64	53.0	4.93e-01	88.0%	75.6%
4ic6C01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.64	51.0	4.98e-01	85.0%	89.1%
2z9iC01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.64	50.0	5.22e-01	83.0%	93.5%
4ri0A01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.64	54.0	4.25e-01	91.0%	49.5%
5y2dA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.63	52.0	4.91e-01	89.0%	73.3%
5hmaA01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.63	50.0	5.35e-01	84.0%	98.9%
2wv9A01	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.60	54.0	4.45e-01	100.0%	56.4%
4m9fA00	2.40.10.120	Mainly Beta › Beta Barrel › Thrombin, subunit H ›	0.58	53.0	4.21e-01	100.0%	57.5%
3e1tA02	3.30.9.100	Alpha Beta › 2-Layer Sandwich › D-Amino Acid Oxidase; Chain A, domain 2 ›	0.56	42.0	3.58e-01	80.0%	72.3%
2zu2A01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.55	43.0	4.40e-01	85.0%	90.8%
3sz6A00	2.60.40.1850	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.54	40.0	3.85e-01	79.0%	91.4%
2wdtC02	3.30.1490.420	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ubiquitin carboxyl-terminal hydrolase, domain 2	0.52	36.0	3.64e-01	84.0%	70.3%
5lohB01	3.30.200.20	Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1	0.52	33.0	3.73e-01	78.0%	86.5%
2ynaA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.52	39.0	4.14e-01	81.0%	100.0%
1th0B00	3.40.395.10	Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A	0.51	43.0	3.40e-01	94.0%	67.7%
1dobA02	3.30.9.10	Alpha Beta › 2-Layer Sandwich › D-Amino Acid Oxidase; Chain A, domain 2 › D-Amino Acid Oxidase, subunit A, domain 2	0.51	39.0	3.43e-01	81.0%	69.6%
3qugA00	2.60.40.1850	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.51	39.0	3.81e-01	82.0%	92.9%

ECOD (12)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1161323	1.1.5.14 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S29	0.87	75.0	5.97e-01	90.0%	54.7%
None	—		0.73	53.0	4.37e-01	74.0%	46.4%
4974463	1.1.17.0 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2	0.73	52.0	4.36e-01	73.0%	51.5%
5018347	1.1.17.0 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2	0.72	51.0	4.39e-01	73.0%	52.3%
169988	1.1.5.6 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S7	0.68	51.0	4.18e-01	78.0%	46.2%
3637221	1.1.5.33 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2	0.67	61.0	4.43e-01	100.0%	51.3%
3957702	1.1.5.33 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2	0.66	56.0	5.07e-01	92.0%	69.6%
3464866	1.1.5.33 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2	0.64	54.0	4.66e-01	91.0%	73.3%
3443107	1.1.17.3 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2	0.63	55.0	4.16e-01	94.0%	47.1%
1311889	1.1.5.7 ↗	beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel	0.58	53.0	3.96e-01	100.0%	84.6%
3199835	220.1.1.0 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like	0.56	30.0	3.41e-01	78.0%	69.3%
3271417	219.1.1.23 ↗	a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › MINDY_DUB	0.52	39.0	2.99e-01	82.0%	60.8%

D5 medium residues 101-183

PDB

Domain cluster: rep: putative_NS3_peptide__YP_009227300__Human_pegivirus_2__1729141__D102-168

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02907.22 best	Peptidase_S29	92.3	3.60e-26	94.0%	50.3%