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NS3

Euk-Vir

Umatilla_virus

NS3__YP_009047250__Umatilla_virus__40060

Identity

Accession:
YP_009047250 ↗
Protein ID:
NS3
Kingdom:
euk

Quality

70.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 94-143
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01616.23 best Orbi_NS3 49.4 5.90e-13 100.0% 27.0%
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7a0hA01 3.30.1140.60 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › F-actin capping protein, alpha subunit 0.71 48.0 3.77e-01 74.0% 34.7%
2kz5A00 1.10.880.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor Skn-1; Chain P › Transcription factor, Skn-1-like, DNA-binding domain 0.64 44.0 3.67e-01 72.0% 40.7%
1sy7A02 1.20.1370.20 Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › Catalase, four-helical domain 0.62 47.0 4.39e-01 86.0% 95.3%
2vx2G02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.58 42.0 4.10e-01 78.0% 69.1%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4433755 109.4.1.1253 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Atp25_C 0.61 44.0 2.87e-01 82.0% 15.3%
D2 medium residues 144-249
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01616.23 best Orbi_NS3 47.0 3.10e-12 100.0% 48.3%
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.89 44.0 4.52e-01 89.6% 50.5%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.87 73.0 5.43e-01 99.1% 39.0%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.87 48.0 5.87e-01 97.2% 83.1%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.83 73.0 6.61e-01 98.1% 71.2%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.82 77.0 6.59e-01 100.0% 87.4%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.81 54.0 6.44e-01 71.7% 97.3%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.80 56.0 6.19e-01 79.2% 88.5%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.78 63.0 6.54e-01 92.5% 91.0%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.78 54.0 6.20e-01 71.7% 98.7%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.78 57.0 6.43e-01 76.4% 97.6%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.77 72.0 5.37e-01 100.0% 43.3%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.76 70.0 5.48e-01 99.1% 49.3%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.76 55.0 5.98e-01 79.2% 88.9%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.76 69.0 6.15e-01 99.1% 91.1%
1fxkC00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 66.0 6.05e-01 92.5% 85.0%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.75 54.0 5.38e-01 75.5% 72.9%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 69.0 5.20e-01 99.1% 44.7%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.74 44.0 4.08e-01 88.7% 47.4%
2ke4A00 6.10.140.470 Special › Helix non-globular › Helix Hairpins › 0.74 57.0 5.89e-01 80.2% 86.7%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 69.0 5.88e-01 100.0% 68.3%
3zbhA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.73 57.0 6.14e-01 83.0% 97.8%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 60.0 4.77e-01 99.1% 45.0%
3qa8A04 1.20.1270.250 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.72 66.0 5.05e-01 100.0% 57.1%
3fb2A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 47.0 4.74e-01 76.4% 66.7%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 42.0 4.94e-01 81.1% 87.3%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.71 54.0 5.71e-01 79.2% 95.8%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 65.0 4.97e-01 100.0% 56.8%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 58.0 5.80e-01 90.6% 86.2%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.70 62.0 4.80e-01 100.0% 92.1%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.69 57.0 4.00e-01 97.2% 28.2%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.68 59.0 4.52e-01 95.3% 44.5%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.67 50.0 4.43e-01 76.4% 57.8%
3t46A00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.67 32.0 3.76e-01 71.7% 62.7%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.67 46.0 4.77e-01 73.6% 74.5%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.67 47.0 4.99e-01 72.6% 100.0%
6bl6B01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.65 54.0 3.86e-01 90.6% 30.7%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.65 57.0 4.08e-01 98.1% 96.6%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.59 52.0 4.96e-01 100.0% 88.0%
2m6bA00 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.52 39.0 3.55e-01 80.2% 93.3%
ECOD (50)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5082443 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.92 77.0 6.75e-01 100.0% 63.4%
3365701 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.90 67.0 6.63e-01 89.6% 73.6%
3744874 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.85 80.0 6.03e-01 100.0% 46.2%
3962893 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.85 62.0 6.59e-01 90.6% 85.3%
5020818 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 80.0 5.01e-01 100.0% 21.9%
4576287 3755.3.1.471 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Paralemmin 0.82 78.0 6.69e-01 100.0% 67.7%
3715884 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.82 78.0 5.88e-01 100.0% 49.1%
4972214 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.82 77.0 4.87e-01 100.0% 43.3%
3615971 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 76.0 6.15e-01 100.0% 59.5%
4031283 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 77.0 6.68e-01 100.0% 72.7%
4957994 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.80 75.0 5.21e-01 100.0% 51.6%
3712648 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.80 76.0 6.08e-01 100.0% 55.8%
2081472 3755.4.1.1 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 0.80 75.0 6.26e-01 100.0% 67.1%
4994979 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.80 69.0 5.48e-01 89.6% 88.4%
3559003 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.80 63.0 6.56e-01 83.0% 88.0%
4992337 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.79 59.0 5.35e-01 77.4% 60.0%
4676422 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.79 70.0 5.83e-01 94.3% 77.1%
3996264 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.78 73.0 6.13e-01 100.0% 62.9%
1495253 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.78 63.0 6.54e-01 92.5% 91.0%
5025381 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.78 73.0 5.01e-01 100.0% 50.0%
5059556 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.77 69.0 5.69e-01 93.4% 85.7%
4983461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.77 64.0 6.13e-01 95.3% 77.5%
3696922 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.77 65.0 5.75e-01 100.0% 63.3%
3471820 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.77 71.0 5.40e-01 98.1% 46.5%
3207569 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.77 70.0 5.54e-01 99.1% 51.5%
1171038 3755.3.1.148 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CT398_CC 0.76 69.0 5.56e-01 96.2% 53.9%
3359919 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.76 56.0 5.61e-01 75.5% 74.1%
3192846 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.76 55.0 5.15e-01 74.5% 63.2%
3923562 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 69.0 4.48e-01 100.0% 24.1%
4315070 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 67.0 5.54e-01 95.3% 57.1%
3824276 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.75 48.0 4.00e-01 89.6% 38.3%
3679787 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.75 59.0 4.28e-01 89.6% 32.2%
5031890 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 68.0 5.08e-01 97.2% 43.3%
4018440 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.75 56.0 5.88e-01 77.4% 86.3%
4809272 3291.1.1.4 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 0.74 63.0 6.01e-01 90.6% 81.8%
5009131 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.73 67.0 5.72e-01 99.1% 64.2%
3788782 2004.1.1.199 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B 0.72 64.0 4.05e-01 96.2% 51.1%
3560590 3755.3.1.142 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › FAM186A-B_C 0.72 59.0 5.21e-01 89.6% 61.3%
5065057 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 65.0 5.66e-01 99.1% 66.5%
3831567 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 65.0 5.51e-01 100.0% 64.1%
4862474 3291.1.1.4 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 0.70 59.0 5.37e-01 90.6% 69.7%
4024105 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 65.0 4.71e-01 100.0% 62.9%
4969096 3926.1.1.0 alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D 0.68 61.0 4.64e-01 99.1% 42.8%
3825161 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.67 62.0 4.60e-01 100.0% 41.2%
2126785 3755.4.1.1 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 0.67 60.0 5.21e-01 100.0% 65.6%
3584613 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.65 54.0 3.91e-01 90.6% 33.7%
3804937 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.65 57.0 5.04e-01 99.1% 80.0%
3404270 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.63 55.0 5.16e-01 100.0% 79.2%
3254136 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.62 51.0 3.67e-01 89.6% 97.5%
3763838 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.61 55.0 3.88e-01 99.1% 91.5%